A. Shaw

发表

Structure–activity relationship study of growth inhibitory 2-styrylchromones against carcinoma cells

C. Hulme, Chen Lin, P. Lu, 2013, Medicinal Chemistry Research.

Synthesis of 2-styrylchromones as a novel class of antiproliferative agents targeting carcinoma cells.

P. Lu, Chia-Ning Yang, A. Shaw, 2009, European journal of medicinal chemistry.

MCRs reshaped into a switchable microwave-assisted protocol toward 5-aminoimidazoles and dihydrotriazines.

C. Hulme, A. Shaw, C. E. Bell, 2014, Tetrahedron.

Recent Advances in Multicomponent Reaction Chemistry

C. Hulme, A. Shaw, F. Medda, 2015 .

Ugi/Robinson-Gabriel reactions directed toward the synthesis of 2,4,5-trisubstituted oxazoles.

C. Hulme, A. Shaw, Zhigang Xu, 2012, Tetrahedron letters.

Two step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines.

Justin D Dietrich, C. Hulme, A. Shaw, 2010, Tetrahedron letters.

Synthesis of (E)-5-methoxy-2-styryl-4-pyrones as potent growth-inhibitory agents against hepatocellular carcinoma cells

C. Hulme, P. Lu, A. Shaw, 2014 .

Two step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines.

Justin D Dietrich, C. Hulme, A. Shaw, 2010, Tetrahedron letters.

Selenium dioxide-mediated synthesis of α-ketoamides from arylglyoxals and secondary amines.

C. Hulme, A. Shaw, Christine R. Denning, 2012, Tetrahedron letters.

Synthesis of kojic acid-derived copper-chelating apoptosis inducing agents

C. Hulme, P. Lu, A. Shaw, 2012, Medicinal Chemistry Research.

Synthesis and structure-activity relationship study of 8-hydroxyquinoline-derived Mannich bases as anticancer agents.

P. Lu, Chia-Ning Yang, A. Shaw, 2010, European journal of medicinal chemistry.

Synthesis and pharmacological exploitation of clioquinol-derived copper-binding apoptosis inducers triggering reactive oxygen species generation and MAPK pathway activation.

P. Lu, Chia-Ning Yang, A. Shaw, 2009, Bioorganic & medicinal chemistry.

Facile and rapid route for the synthesis of novel norstatine analogs via PADAM-cyclization methodology

C. Hulme, A. Shaw, F. Medda, 2012 .

Applications of ortho-phenylisonitrile and ortho-N-Boc aniline for the two-step preparation of novel bis-heterocyclic chemotypes

C. Hulme, A. Shaw, G. Nichol, 2012, Molecular Diversity.

Facile, novel two-step syntheses of benzimidazoles, bis-benzimidazoles, and bis-benzimidazole-dihydroquinoxalines

Justin D Dietrich, C. Hulme, A. Shaw, 2012, Molecular Diversity.

Two-Step Route to Diverse N-Functionalized Peptidomimetic-like Isatins through an Oxidation/Intramolecular Oxidative-Amidation Cascade of Ugi Azide and Ugi Three-Component Reaction Products.

C. Hulme, A. Shaw, C. Foley, 2016, Organic letters.

Recent Applications of Multicomponent Reactions Toward Heterocyclic Drug Discovery

C. Hulme, A. Shaw, Alessandra Fistrovich, 2021, Multicomponent Reactions towards Heterocycles.

Aza-Riley Oxidation of Ugi-Azide and Ugi-3CR Products toward Vicinal Tricarbonyl Amides: Two-Step MCR-Oxidation Methodology Accessing Functionalized α,β-Diketoamides and α,β-Diketotetrazoles.

C. Hulme, A. Shaw, C. Foley, 2018, Organic letters.

Synthesis and Antiproliferative Evaluation of 2′‐Arenesulfonyloxy‐5‐benzylidene‐thiazolidine‐2,4‐diones

P. Lu, A. Shaw, EmilyY . Chen, 2012 .

Characterization of Novel Diaryl Oxazole-Based Compounds as Potential Agents to Treat Pancreatic Cancer

Meredith C Henderson, A. Shaw, L. Hurley, 2009, Journal of Pharmacology and Experimental Therapeutics.

Hydrazine-mediated cyclization of Ugi products to synthesize novel 3-hydroxypyrazoles.

C. Hulme, A. Shaw, G. Nichol, 2012, Tetrahedron letters.

3,5-Diaryl-1H-pyrazole as a molecular scaffold for the synthesis of apoptosis-inducing agents.

P. Lu, Chia-Ning Yang, A. Shaw, 2010, Bioorganic & medicinal chemistry.

Oxidative Deaminations and Deisatinylations of Ugi-Azide and Ugi-3CR Products: A Two-Step MCR-Oxidation Protocol toward Functionalized α-Ketoamides and α-Ketotetrazoles.

C. Hulme, A. Shaw, C. Foley, 2017, Organic letters.

Estimation of the Capability of Surfactant in Reducing the Interfacial Tension in Surfactant/Alkali/Crude Oil Systems via Quantification

A. Shaw, W. Qiao, A. Cappelli, 2013 .

Branched Chains of Arylalkyl Surfactants Effects on the Interfacial Tension Between Crude Oil/Surfactant-Alkaline Systems

A. Shaw, W. Qiao, Zongshi Li, 2012 .

Beyond secretases: Kinase inhibitors for the treatment of Alzheimer's disease

T. Dunckley, C. Hulme, A. Shaw, 2013 .

Identification of novel DNA methylation inhibitors via a two-component reporter gene system

A. Shaw, M. Tseng, Chia-Chen Hsu, 2011, Journal of Biomedical Science.

Microwave-Assisted Base-Catalyzed Cyclization and Nucleophilic Substitution of O-Azidobenzanilides to Synthesize 1,2-Disubstituted Indazol-3-ones

A. Shaw, Chia-Hua Tsai, Yi-Ru Chen, 2009 .

Dyrk1 inhibition improves Alzheimer's disease‐like pathology

T. Dunckley, C. Hulme, A. Shaw, 2017, Aging cell.

Synthesis of Di- and Tri-Substituted Imidazole-4-carboxylates via PBu3-Mediated [3 + 2] Cycloaddition

Justin D Dietrich, C. Hulme, A. Shaw, 2013 .

Synthesis of Di‐ and Tri‐Substituted Imidazole‐4‐carboxylates via PBu3‐Mediated [3 + 2] Cycloaddition

Justin D Dietrich, C. Hulme, A. Shaw, 2013 .

Applications of ortho-phenylisonitrile and ortho-N-Boc aniline for the two-step preparation of novel bis-heterocyclic chemotypes

C. Hulme, A. Shaw, Zhigang Xu, 2012, Molecular Diversity.

Facile, novel two-step syntheses of benzimidazoles, bis-benzimidazoles, and bis-benzimidazole-dihydroquinoxalines

Justin D Dietrich, C. Hulme, A. Shaw, 2012, Molecular Diversity.

Structure–activity relationship study of growth inhibitory 2-styrylchromones against carcinoma cells

C. Hulme, Chen Lin, P. Lu, 2013, Medicinal Chemistry Research.

Synthesis of kojic acid-derived copper-chelating apoptosis inducing agents

C. Hulme, Yu-hua Chen, P. Lu, 2013, Medicinal Chemistry Research.

Copper(i) catalyzed oxidative hydrolysis of Ugi 3-component and Ugi-azide reaction products towards 2° α-ketoamides and α-ketotetrazoles.

C. Hulme, A. Shaw, R. Orru, 2017, Organic & biomolecular chemistry.

Chronic Dyrk1 Inhibition Delays the Onset of AD-Like Pathology in 3xTg-AD Mice

T. Dunckley, C. Hulme, A. Shaw, 2019, Molecular Neurobiology.

Chronic Dyrk1 Inhibition Delays the Onset of AD-Like Pathology in 3xTg-AD Mice

T. Dunckley, A. Shaw, A. Ow, 2019, Molecular Neurobiology.