Ming Zhao

发表

Phase 1 and pharmacokinetic study of bolus-infusion flavopiridol followed by cytosine arabinoside and mitoxantrone for acute leukemias.

M. McDevitt, L. Doyle, B. Smith, 2011, Blood.

A rapid and sensitive method for determination of sorafenib in human plasma using a liquid chromatography/tandem mass spectrometry assay.

M. Hidalgo, S. Baker, B. Smith, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer.

J. Herman, S. Baylin, M. Brock, 2011, Cancer discovery.

Determination of the docetaxel vehicle, polysorbate 80, in patient samples by liquid chromatography-tandem mass spectrometry.

J. Verweij, S. Baker, A. Sparreboom, 2002, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Phase I pharmacokinetic and pharmacodynamic study of cetuximab, irinotecan and sorafenib in advanced colorectal cancer

L. Diaz, M. Hidalgo, M. Carducci, 2013, Investigational New Drugs.

A pharmacodynamic study of sorafenib in patients with relapsed and refractory acute leukemias

M. McDevitt, M. Carducci, S. Baker, 2010, Leukemia.

CYP3A phenotyping approach to predict systemic exposure to EGFR tyrosine kinase inhibitors.

Manuel Hidalgo, Ming Zhao, Mats O Karlsson, 2006, Journal of the National Cancer Institute.

CYP 3 A Phenotyping Approach to Predict Systemic Exposure to EGFR Tyrosine Kinase Inhibitors

M. Hidalgo, M. Karlsson, S. Baker, 2022 .

Cancer Therapy: Clinical A Phase I Dose-Finding Study of 5-Azacytidine in Combination with Sodium Phenylbutyrate in Patients with Refractory Solid Tumors

J. Herman, M. Carducci, J. Gilbert, 2009 .

A Phase I Dose-Finding Study of 5-Azacytidine in Combination with Sodium Phenylbutyrate in Patients with Refractory Solid Tumors

J. Herman, M. Carducci, J. Gilbert, 2009, Clinical Cancer Research.

Distribution of paclitaxel in plasma and cerebrospinal fluid

J. Verweij, H. Gelderblom, S. Baker, 2003, Anti-Cancer Drugs.

Local delivery of rapamycin: a toxicity and efficacy study in an experimental malignant glioma model in rats.

I. Siu, G. Gallia, J. Rosenblatt, 2011, Neuro-oncology.

Glutamate carboxypeptidase activity in human skin biopsies as a pharmacodynamic marker for clinical studies

G. Ebenezer, M. Rudek, Ming Zhao, 2011, Journal of Translational Medicine.

Quantitation of sorafenib and its active metabolite sorafenib N-oxide in human plasma by liquid chromatography-tandem mass spectrometry.

S. Baker, M. Rudek, K. Pratz, 2010, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Simultaneous analysis of docetaxel and the formulation vehicle polysorbate 80 in human plasma by liquid chromatography/tandem mass spectrometry.

J. Verweij, M. Carducci, S. Baker, 2004, Analytical Biochemistry.

Differential Metabolism of Gefitinib and Erlotinib by Human Cytochrome P450 Enzymes

M. Hidalgo, S. Baker, Ming Zhao, 2007, Clinical Cancer Research.

Validation and implementation of a liquid chromatography/tandem mass spectrometry assay to quantitate ABT-751, ABT-751 glucuronide, and ABT-751 sulfate in human plasma for clinical pharmacology studies.

S. Baker, M. Rudek, Ming Zhao, 2006, Journal of pharmaceutical and biomedical analysis.

Validation and implementation of a liquid chromatography/tandem mass spectrometry assay to quantitate dimethyl benzoylphenylurea (BPU) and its five metabolites in human plasma and urine for clinical pharmacology studies.

A. Wolff, S. Baker, M. Rudek, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Specific method for determination of gefitinib in human plasma, mouse plasma and tissues using high performance liquid chromatography coupled to tandem mass spectrometry.

A. Jimeno, M. Hidalgo, S. Baker, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Pharmacodynamic-guided modified continuous reassessment method-based, dose-finding study of rapamycin in adult patients with solid tumors.

A. Jimeno, M. Hidalgo, R. Donehower, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Thioridazine lacks bactericidal activity in an animal model of extracellular tuberculosis.

M. Rudek, Ming Zhao, P. Karakousis, 2013, The Journal of antimicrobial chemotherapy.

A polymeric nanoparticle formulation of curcumin (NanoCurc™) ameliorates CCl4-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation

Toby C. Cornish, A. Maitra, A. Maitra, 2011, Laboratory Investigation.

Simultaneous determination of steroid composition of human testicular fluid using liquid chromatography tandem mass spectrometry

S. Baker, Ming Zhao, B. Zirkin, 2004, Steroids.

Quantitative assessment of seminal vesicle and prostate drug concentrations by use of a noninvasive method

B. Caffo, Leena Choi, Ming Zhao, 2006, Clinical pharmacology and therapeutics.

Influence of CYP3A4 Inhibition on the Steady-State Pharmacokinetics of Imatinib

J. Nortier, H. Guchelaar, M. Karlsson, 2007, Clinical Cancer Research.

Phase I study of continuous weekly dosing of dimethylamino benzoylphenylurea (BPU) in patients with solid tumours.

A. Wolff, M. Carducci, R. Donehower, 2007, European Journal of Cancer.

In vitro and In vivo Clinical Pharmacology of Dimethyl Benzoylphenylurea, a Novel Oral Tubulin-Interactive Agent

Manuel Hidalgo, Ming Zhao, Robert W. Robey, 2005, Clinical Cancer Research.

A method for determination of dimethyl benzoylphenyl urea (BPU) in human plasma by using LC/UV.

A. Wolff, S. Baker, M. Rudek, 2004, Biomedical chromatography : BMC.

Synthesis and antitumor evaluation of benzoylphenylurea analogs.

M. Hidalgo, M. Rudek, Ming Zhao, 2004, Bioorganic & medicinal chemistry letters.

A rapid and sensitive method for determination of dimethyl benzoylphenyl urea in human plasma by using LC/MS/MS.

A. Wolff, S. Baker, M. Rudek, 2003, Journal of pharmaceutical and biomedical analysis.

Comparative Pharmacokinetics of Weekly and Every-Three-Weeks Docetaxel

Ming Zhao, Alex Sparreboom, A. Wolff, 2004, Clinical Cancer Research.

Repurposing itraconazole as a treatment for advanced prostate cancer: a noncomparative randomized phase II trial in men with metastatic castration-resistant prostate cancer.

Ming Zhao, David C. Smith, Janet Mendonca, 2013, The oncologist.

Bisphosphonamidate clodronate prodrug exhibits potent anticancer activity in non-small-cell lung cancer cells.

M. Rudek, Ming Zhao, C. Hann, 2011, Journal of medicinal chemistry.

A liquid chromatography/tandem mass spectrometry assay to quantitate MS-275 in human plasma.

S. Baker, M. Rudek, Ming Zhao, 2007, Journal of pharmaceutical and biomedical analysis.

Limited cerebrospinal fluid penetration of docetaxel

J. Verweij, S. Baker, A. Sparreboom, 2004, Anti-cancer drugs.

Specific method for determination of OSI-774 and its metabolite OSI-420 in human plasma by using liquid chromatography-tandem mass spectrometry.

M. Hidalgo, S. Baker, M. Rudek, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Differentiation therapy in poor risk myeloid malignancies: Results of a dose finding study of the combination bryostatin-1 and GM-CSF.

Zhe Zhang, S. Piantadosi, J. Kowalski, 2011, Leukemia research.

Subcutaneous implants for long-acting drug therapy in laboratory animals may generate unintended drug reservoirs

Ming Zhao, B. Tyler, M. Guarnieri, 2014, Journal of pharmacy & bioallied sciences.

Validation and implementation of a method for determination of bryostatin 1 in human plasma by using liquid chromatography/tandem mass spectrometry.

S. Baker, B. Smith, M. Rudek, 2005, Analytical biochemistry.

Quantification of sunitinib in human plasma by high-performance liquid chromatography-tandem mass spectrometry.

H. Gelderblom, S. Baker, Ming Zhao, 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Intraductal administration of a polymeric nanoparticle formulation of curcumin (NanoCurc) significantly attenuates incidence of mammary tumors in a rodent chemical carcinogenesis model: Implications for breast cancer chemoprevention in at-risk populations.

S. Sukumar, A. Maitra, Seung‐Mo Hong, 2012, Carcinogenesis.

Combined DNA methyltransferase and histone deacetylase inhibition in the treatment of myeloid neoplasms.

M. Grever, J. Herman, S. Baylin, 2006, Cancer research.

Integrated preclinical and clinical development of S-trans, trans-farnesylthiosalicylic acid (FTS, Salirasib) in pancreatic cancer

A. Jimeno, M. Hidalgo, R. Donehower, 2012, Investigational New Drugs.

A Polymeric Nanoparticle Encapsulated Small-Molecule Inhibitor of Hedgehog Signaling (NanoHHI) Bypasses Secondary Mutational Resistance to Smoothened Antagonists

C. Rudin, A. Maitra, Seung‐Mo Hong, 2011, Molecular Cancer Therapeutics.

Phase I trial of oxaliplatin, infusional 5-fluorouracil, and leucovorin (FOLFOX4) with erlotinib and bevacizumab in colorectal cancer.

C. Iacobuzio-Donahue, A. Jimeno, M. Hidalgo, 2010, Clinical colorectal cancer.

A bis-benzylidine piperidone targeting proteasome ubiquitin receptor RPN13/ADRM1 as a therapy for cancer.

R. Roden, R. Orlowski, M. Rudek, 2013, Cancer cell.

Interaction of the Multikinase Inhibitors Sorafenib and Sunitinib with Solute Carriers and ATP-Binding Cassette Transporters

S. Baker, R. Franke, A. Sparreboom, 2009, Clinical Cancer Research.

A sensitive method for determination of COL-3, a chemically modified tetracycline, in human plasma using high-performance liquid chromatography and ultraviolet detection.

S. Baker, M. Rudek, Ming Zhao, 2005, Journal of pharmaceutical and biomedical analysis.

Bisphosphonamidate Clodronate Prodrug Exhibits Selective Cytotoxic Activity against Melanoma Cell Lines

A. Weeraratna, M. Rudek, Ming Zhao, 2013, Molecular Cancer Therapeutics.

Pharmacokinetics of 5-azacitidine administered with phenylbutyrate in patients with refractory solid tumors or hematologic malignancies.

M. Carducci, J. Gilbert, S. Baker, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Local delivery of cancer-cell glycolytic inhibitors in high-grade glioma.

H. Bow, M. Rudek, Ming Zhao, 2015, Neuro-oncology.

Effect of Milk Thistle (Silybum marianum) on the Pharmacokinetics of Irinotecan

J. Nortier, H. Guchelaar, H. Gelderblom, 2005, Clinical Cancer Research.

Fixed-dose capecitabine is feasible: results from a pharmacokinetic and pharmacogenetic study in metastatic breast cancer

A. Wolff, H. McLeod, N. Davidson, 2013, Breast Cancer Research and Treatment.

Validation and implementation of a liquid chromatography/tandem mass spectrometry assay to quantitate ON 01910.Na, a mitotic progression modulator, in human plasma.

A. Jimeno, M. Hidalgo, R. Donehower, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Bioanalytical method for evaluating the pharmacokinetics of the GCP-II inhibitor 2-phosphonomethyl pentanedioic acid (2-PMPA).

M. Rudek, Ming Zhao, T. Tsukamoto, 2014, Journal of pharmaceutical and biomedical analysis.

Sertraline slows disease progression and increases neurogenesis in N171-82Q mouse model of Huntington's disease

Erik Tryggestad, Christopher A. Ross, Wenzhen Duan, 2008, Neurobiology of Disease.

The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model

Christopher A. Ross, Wenzhen Duan, Mali Jiang, 2008, Experimental Neurology.

Tiagabine is neuroprotective in the N171-82Q and R6/2 mouse models of Huntington's disease

C. Ross, Ming Zhao, W. Duan, 2008, Neurobiology of Disease.

Quantification of 5-azacytidine in plasma by electrospray tandem mass spectrometry coupled with high-performance liquid chromatography.

M. Carducci, S. Baker, M. Rudek, 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Docetaxel metabolism is not altered by imatinib: findings from an early phase study in metastatic breast cancer

A. Wolff, L. Emens, N. Davidson, 2011, Breast Cancer Research and Treatment.

A rapid and sensitive method for determination of veliparib (ABT-888), in human plasma, bone marrow cells and supernatant by using LC/MS/MS.

J. Karp, M. Rudek, Ming Zhao, 2010, Journal of pharmaceutical and biomedical analysis.

A glutamate receptor antagonist, S-4-carboxyphenylglycine (S-4-CPG), inhibits vasospasm after subarachnoid hemorrhage in haptoglobin 2-2 mice [corrected].

G. Riggins, R. Tamargo, R. Grossman, 2013, Neurosurgery.

Quantitation of unbound sunitinib and its metabolite N-desethyl sunitinib (SU12662) in human plasma by equilibrium dialysis and liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study.

M. Rudek, Ming Zhao, P. He, 2012, Biomedical chromatography : BMC.

cis-3, 4′, 5-Trimethoxy-3′-aminostilbene disrupts tumor vascular perfusion without damaging normal organ perfusion

P. Fatouros, M. Rudek, Ming Zhao, 2008, Cancer Chemotherapy and Pharmacology.

Phase I trial of continuous infusion 5-aza-2′-deoxycytidine

P. Laird, L. Leong, S. Baker, 2003, Cancer Chemotherapy and Pharmacology.

Phase I study of the histone deacetylase inhibitor entinostat in combination with 13-cis retinoic acid in patients with solid tumours

D. Qian, M. Carducci, M. Rudek, 2011, British Journal of Cancer.

Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer.

J. Herman, S. Baylin, M. Brock, 2011, Cancer discovery.

Subcutaneous implants for long-acting drug therapy in laboratory animals may generate unintended drug reservoirs

Ming Zhao, B. Tyler, M. Guarnieri, 2014, Journal of pharmacy & bioallied sciences.