D. Price

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Nucleophosmin interacts with HEXIM1 and regulates RNA polymerase II transcription.

T. Lim, D. Lane, Jialing Lee, 2008, Journal of molecular biology.

Flavopiridol Inactivates P-TEFb and Blocks Most RNA Polymerase II Transcription in Vivo *

D. Price, Sheng Chao, David H. Price, 2001, The Journal of Biological Chemistry.

Flavopiridol Inhibits P-TEFb and Blocks HIV-1 Replication*

E. Sausville, B. Peterlin, A. Senderowicz, 2000, The Journal of Biological Chemistry.

Identification of multiple cyclin subunits of human P-TEFb.

J. Milton, Y. Zhu, D. Price, 1998, Genes & development.

Analysis of RNA polymerase II elongation in vitro.

D. Price, T. E. Adamson, Sarah M. Shore, 2003, Methods in enzymology.

RNA polymerase II elongation control.

Y. Zhu, D. Price, J. Peng, 1998, Cold Spring Harbor symposia on quantitative biology.

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

Mathieu Blanchette, Benoit Coulombe, Jack Greenblatt, 2007, Molecular cell.

Drosophila RNA Polymerase II Mutants That Affect Transcription Elongation (*)

A. Greenleaf, D. Price, Y. Chen, 1996, The Journal of Biological Chemistry.

Functional coupling of capping and transcription of mRNA.

D. Price, S. Moteki, 2002, Molecular cell.

Identification of a Cyclin Subunit Required for the Function ofDrosophila P-TEFb*

D. Price, N. Marshall, Junmin Peng, 1998, The Journal of Biological Chemistry.

Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation

A. Spivak, D. Margolis, N. Archin, 2017, Cell reports.

Involvement of transcription termination factor 2 in mitotic repression of transcription elongation.

Yan Jiang, D. Price, C. Spencer, 2004, Molecular cell.

Effect of mimetic CDK9 inhibitors on HIV-1-activated transcription.

Z. Klase, S. Nekhai, F. Kashanchi, 2013, Journal of molecular biology.

Manipulation of P-TEFb control machinery by HIV: recruitment of P-TEFb from the large form by Tat and binding of HEXIM1 to TAR

D. Price, W. Maury, S. Sedore, 2007, Nucleic acids research.

Estrogens in the Environment

O. Bensaude, D. Price, V. T. Nguyen, 1997, Environmental Health Perspectives.

HEXIM 1 is a promiscuous double-stranded RNA-binding protein and interacts with RNAs in addition to 7 SK in cultured cells

M. A. Shea, Qintong Li, D. Price, 2007 .

HEXIM1 is a promiscuous double-stranded RNA-binding protein and interacts with RNAs in addition to 7SK in cultured cells

M. A. Shea, Qintong Li, D. Price, 2007, Nucleic acids research.

Retrovirology BioMed Central

O. Bensaude, D. Price, V. T. Nguyen, 2006 .

Characterization of Cdk9(55) and differential regulation of two Cdk9 isoforms.

P. Dent, D. Price, Sarah M. Shore, 2005, Gene.

The antiproliferative agent MLN944 preferentially inhibits transcription

D. Price, D. Sappal, B. Schafer, 2005, Molecular Cancer Therapeutics.

Dynamic interaction between a Drosophila transcription factor and RNA polymerase II

A. Sluder, A. Greenleaf, D. Price, 1989, Molecular and cellular biology.

Functional Coupling of Cleavage and Polyadenylation with Transcription of mRNA*

D. Shutt, D. Price, T. E. Adamson, 2005, Journal of Biological Chemistry.

Hydrogen peroxide yields mechanistic insights into human mRNA capping enzyme function

D. Price, Nicholas J. Mullen, 2017, PloS one.

Isolation and functional analysis of RNA polymerase II elongation complexes.

D. Price, B. Cheng, 2009, Methods.

Purification of an RNA Polymerase II Transcript Release Factor from Drosophila(*)

D. Price, Z. Xie, Zhi Xie, 1996, The Journal of Biological Chemistry.

Cotranscriptional Processing of Drosophila Histone mRNAs

D. Price, T. E. Adamson, 2003, Molecular and Cellular Biology.

Properties of RNA Polymerase II Elongation Complexes Before and After the P-TEFb-mediated Transition into Productive Elongation*

D. Price, B. Cheng, 2007, Journal of Biological Chemistry.

Cyclin K Functions as a CDK9 Regulatory Subunit and Participates in RNA Polymerase II Transcription*

Junmin Peng, D. Price, T. Fu, 1999, The Journal of Biological Chemistry.

THZ1 Reveals Roles for Cdk7 in Co-transcriptional Capping and Pausing.

D. Price, D. Luse, John E. Brogie, 2015, Molecular cell.

Functional interaction of human Ssu72 with RNA polymerase II complexes

D. Price, Michał Turek, Benjamin M Spector, 2019, PloS one.

Regulation of RNA Polymerase II Termination by Phosphorylation of Gdown1*

D. Price, Michał Turek, Jiannan Guo, 2014, The Journal of Biological Chemistry.

Differential dependencies of human RNA polymerase II promoters on TBP, TAF1, TFIIB and XPB

D. Price, Juan F. Santana, Mrutyunjaya Parida, 2022, Nucleic acids research.

Regulation of MYC Expression and Differential JQ1 Sensitivity in Cancer Cells

James E. Bradner, Cheng-Ming Chiang, Ananda L. Roy, 2014, PloS one.

Correction: Regulation of MYC Expression and Differential JQ1 Sensitivity in Cancer Cells

A. Shilatifard, J. Bradner, R. Conaway, 2015, PLoS ONE.

Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.

Howard Y. Chang, Ryan A. Flynn, R. Young, 2016, Molecular cell.

Human Transcription Release Factor 2 Dissociates RNA Polymerases I and II Stalled at a Cyclobutane Thymine Dimer*

A. Sancar, R. Hara, D. Price, 1999, Journal of Biological Chemistry.

Mechanism of DmS-II-mediated pause suppression by Drosophila RNA polymerase II.

D. Price, H. Guo, David H. Price, 1993, The Journal of biological chemistry.

Unusual Nucleic Acid Binding Properties of Factor 2, an RNA Polymerase II Transcript Release Factor*

D. Price, Zhiyuan Xie, 1998, The Journal of Biological Chemistry.

Drosophila Factor 2, an RNA Polymerase II Transcript Release Factor, Has DNA-dependent ATPase Activity*

D. Price, Zhiyuan Xie, 1997, The Journal of Biological Chemistry.

Rescue of the TTF2 Knockdown Phenotype with an siRNA-Resistant Replacement Vector

Yan Jiang, D. Price, 2004, Cell cycle.

Action of α-Amanitin during Pyrophosphorolysis and Elongation by RNA Polymerase II (*)

D. Price, D. Chafin, Hong-liang Guo, 1995, The Journal of Biological Chemistry.

Elongation by Drosophila RNA polymerase II. Transcription of 3'-extended DNA templates.

A. Sluder, A. Greenleaf, D. Price, 1988, The Journal of biological chemistry.

A unified view of the sequence and functional organization of the human RNA polymerase II promoter

D. Price, Mrutyunjaya Parida, D. Luse, 2020, Nucleic acids research.

Functional analysis of Drosophila factor 5 (TFIIF), a general transcription factor.

D. Price, Z. Burton, B. Wang, 1994, The Journal of biological chemistry.

A Human RNA Polymerase II Transcription Termination Factor Is a SWI2/SNF2 Family Member*

Z. Xie, D. Price, Mingyi Liu, 1998, The Journal of Biological Chemistry.

Fractionation of transcription factors for RNA polymerase II from Drosophila Kc cell nuclear extracts.

A. Sluder, A. Greenleaf, D. Price, 1987, The Journal of biological chemistry.

Properties of a Drosophila RNA polymerase II elongation factor.

A. Sluder, A. Greenleaf, D. Price, 1989, The Journal of biological chemistry.

The 3′ end of Drosophila histone H3 mRNA is produced by a processing activity in vitro

C. S. Parker, D. Price, 1984, Cell.

Human cytomegalovirus IE2 drives transcription initiation from a select subset of late infection viral promoters by host RNA polymerase II

D. Price, J. Meier, D. Luse, 2020, PLoS pathogens.

Human Cytomegalovirus IE2 Both Activates and Represses Initiation and Modulates Elongation in a Context-Dependent Manner

D. Price, J. Meier, Geoffrey S. Collins, 2022, mBio.

Inhibition of HIV-1 replication by P-TEFb inhibitors DRB, seliciclib and flavopiridol correlates with release of free P-TEFb from the large, inactive form of the complex

O. Bensaude, D. Price, V. T. Nguyen, 2007, Retrovirology.

Differences in RNA polymerase II complexes and their interactions with surrounding chromatin on human and cytomegalovirus genomes

D. Price, J. Meier, D. Luse, 2021, Nature Communications.

Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4

T. Tahirov, D. Price, Yoshiaki Suwa, 2014, Cell cycle.

Dynamic regulation of P-TEFb by 7SK snRNP is integral to the DNA damage response to regulate chemotherapy sensitivity

Qintong Li, D. Price, X. Xiao, 2022, iScience.

Functional Interactions of the RNA Polymerase II-interacting Proteins Gdown1 and TFIIF*

D. Price, D. Luse, Jiannan Guo, 2014, The Journal of Biological Chemistry.

Gdown1

D. Price, Tiandao Li, 2012 .

The metallothionein gene of Drosophila.

D. Price, G. Maroni, D. Lastowski-Perry, 1987, Experientia. Supplementum.

7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcription

B. Peterlin, D. Price, John E. Brogie, 2012, Wiley interdisciplinary reviews. RNA.

Reconstitution of a functional 7SK snRNP

D. Price, John E. Brogie, 2017, Nucleic acids research.

RNA polymerase II elongation control.

Qiang Zhou, D. Price, Tiandao Li, 2012, Annual review of biochemistry.

Upregulation of cyclin T1/CDK9 complexes during T cell activation

X. Graña, Junmin Peng, D. Price, 1998, Oncogene.

Guest Editor's Introduction. Controlling which genes are transcriptionally expressed is key to the generation and maintenance of the repertoire of cell types needed to support the mammalian lifestyle.

D. Price, 2009, Methods.

Runaway transcription

D. Price, Tiandao Li, Jiannan Guo, 2013, Genome Biology.

Juglone, an inhibitor of the peptidyl-prolyl isomerase Pin1, also directly blocks transcription.

A. Greenleaf, D. Price, S. Chao, 2001, Nucleic acids research.

The Role of RNA Polymerase II Elongation Control in HIV-1 Gene Expression, Replication, and Latency

D. Price, Kyle A. Nilson, 2011, Genetics research international.

Sequence specificity incompletely defines the genome-wide occupancy of Myc

Raluca Gordân, R. Gordân, D. Price, 2014, Genome Biology.

RNA polymerase II transcription elongation control.

D. Price, Jiannan Guo, 2013, Chemical reviews.

A negative elongation factor for human RNA polymerase II inhibits the anti-arrest transcript-cleavage factor TFIIS.

R. Landick, M. Palangat, D. Price, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structure of HIV-1 Tat complexed with human P-TEFb

T. Tahirov, D. Price, Katayoun Varzavand, 2010, Nature.

Functional association of Gdown1 with RNA polymerase II poised on human genes.

R. Young, A. Gnatt, P. Rahl, 2012, Molecular cell.

Analysis of factor interactions with RNA polymerase II elongation complexes using a new electrophoretic mobility shift assay

D. Price, B. Cheng, 2008, Nucleic acids research.

A Highly Purified RNA Polymerase II Elongation Control System*

H. Handa, D. Price, T. Wada, 2001, The Journal of Biological Chemistry.

Sequence organization of the poly(A) RNA synthesized and accumulated in lampbrush chromosome stage Xenopus laevis oocytes.

R. Britten, D. Price, J. Richter, 1982, Journal of molecular biology.

An alternative D. melanogaster 7SK snRNP

O. Bensaude, N. Buisine, D. Price, 2021, BMC Molecular and Cell Biology.

The Drosophila 7SK snRNP and the essential role of dHEXIM in development

J. Lis, A. Matera, D. Price, 2012, Nucleic acids research.

Transcription Factor IIS Cooperates with the E3 Ligase UBR5 to Ubiquitinate the CDK9 Subunit of the Positive Transcription Elongation Factor B*

B. Coulombe, D. Price, Philippe Cloutier, 2010, The Journal of Biological Chemistry.

The Mechanism of Release of P-TEFb and HEXIM1 from the 7SK snRNP by Viral and Cellular Activators Includes a Conformational Change in 7SK

D. Price, Katayoun Varzavand, Jeffrey J. Cooper, 2010, PloS one.

Poised polymerases: on your mark...get set...go!

D. Price, 2008, Molecular cell.

LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated

B. Coulombe, O. Bensaude, D. Price, 2008, Nucleic acids research.

Controlling the elongation phase of transcription with P-TEFb.

B. Peterlin, D. Price, 2006, Molecular cell.

Interplay between 7SK snRNA and oppositely charged regions in HEXIM1 direct the inhibition of P‐TEFb

Jirí Kohoutek, B. Peterlin, M. Barborič, 2005, The EMBO journal.

Analysis of the Large Inactive P-TEFb Complex Indicates That It Contains One 7SK Molecule, a Dimer of HEXIM1 or HEXIM2, and Two P-TEFb Molecules Containing Cdk9 Phosphorylated at Threonine 186*

Dongmei Cheng, Junmin Peng, Qintong Li, 2005, Journal of Biological Chemistry.

HEXIM2, a HEXIM1-related Protein, Regulates Positive Transcription Elongation Factor b through Association with 7SK*

Qintong Li, D. Price, David H Price, 2005, Journal of Biological Chemistry.

Binding of the 7SK snRNA turns the HEXIM1 protein into a P‐TEFb (CDK9/cyclin T) inhibitor

Van Trung Nguyen, François Bonnet, O. Bensaude, 2004, The EMBO journal.

Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro.

M. Mathews, Y. Zhu, B. Amendt, 1997, Genes & development.

Varicella-Zoster Virus Fc Receptor Component gI Is Phosphorylated on Its Endodomain by a Cyclin-Dependent Kinase

C. Grose, D. Price, K. Duus, 1999, Journal of Virology.

Endodomain by a Cyclin-Dependent Kinase Component gI Is Phosphorylated on Its Varicella-Zoster Virus Fc Receptor

C. Grose, D. Price, K. Duus, 1998 .

Tat Modifies the Activity of CDK9 To Phosphorylate Serine 5 of the RNA Polymerase II Carboxyl-Terminal Domain during Human Immunodeficiency Virus Type 1 Transcription

Junmin Peng, Matthew A. Halanski, F. Kashanchi, 2000, Molecular and Cellular Biology.

P-TEFb, a Cyclin-Dependent Kinase Controlling Elongation by RNA Polymerase II

D. Price, 2000, Molecular and Cellular Biology.

Confirmation of predicted edits and demonstration of unpredicted edits in Acanthamoeba castellanii mitochondrial tRNAs

D. Price, M. Gray, 1999, Current Genetics.

MYC assembles and stimulates topoisomerases 1 and 2 in a "topoisome".

D. Levens, Laura Baranello, Z. Nie, 2021, Molecular cell.

P-TEFb kinase recruitment and function at heat shock loci.

J. Lis, D. Price, J. Peng, 2000, Genes & development.

Control of RNA Polymerase II Elongation Potential by a Novel Carboxyl-terminal Domain Kinase*

D. Price, N. Marshall, Z. Xie, 1996, The Journal of Biological Chemistry.

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro.

D. Hazuda, Percy Luu, J. Tomassini, 1997, Genes & development.

CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1.

J. Lis, K. Adelman, H. Phatnani, 2010, Genes & development.

Purification of P-TEFb, a Transcription Factor Required for the Transition into Productive Elongation (*)

D. Price, N. Marshall, 1995, The Journal of Biological Chemistry.

Stability of Drosophila RNA polymerase II elongation complexes in vitro

D. Price, N. Marshall, D. Kephart, 1992, Molecular and cellular biology.

Control of formation of two distinct classes of RNA polymerase II elongation complexes

D. Price, N. Marshall, D H Price, 1992, Molecular and cellular biology.

Transcriptional Regulation of the GPX1 Gene by TFAP2C and Aberrant CpG Methylation in Human Breast Cancer

P. Spanheimer, A. Cyr, G. Woodfield, 2012, Oncogene.

Cytomegalovirus late transcription factor target sequence diversity orchestrates viral early to late transcription

D. Price, J. Meier, Geoffrey Collins, 2021, PLoS pathogens.

Nuclear export restricts Gdown1 to a mitotic function

D. Price, Juan F. Santana, Benjamin M Spector, 2022, Nucleic acids research.

Interactions between Tat and TAR and human immunodeficiency virus replication are facilitated by human cyclin T1 but not cyclins T2a or T2b.

B. Peterlin, Y. Zhu, D. Price, 1999, Virology.

TFIIH Inhibits CDK9 Phosphorylation during Human Immunodeficiency Virus Type 1 Transcription*

S. Nekhai, J. Brady, D. Price, 2001, The Journal of Biological Chemistry.

An in vitro transcription system that recapitulates equine infectious anemia virus tat-mediated inhibition of human immunodeficiency virus type 1 Tat activity demonstrates a role for positive transcription elongation factor b and associated proteins in the mechanism of Tat activation.

M. Garcia-Blanco, D. Price, J. Peng, 2000, Virology.

Price II Controlling Elongation by RNA Polymerase P-TEFb , a Cyclin-Dependent Kinase

D. Price, 2000 .

The Ability of Positive Transcription Elongation Factor b To Transactivate Human Immunodeficiency Virus Transcription Depends on a Functional Kinase Domain, Cyclin T1, and Tat

B. Peterlin, X. Graña, Junmin Peng, 1998, Journal of Virology.

Formaldehyde‐assisted isolation of regulatory elements

D. Price, P. L. Nagy, 2009, Wiley interdisciplinary reviews. Systems biology and medicine.

Oxidative stress rapidly stabilizes promoter-proximal paused Pol II across the human genome

D. Price, J. Meier, Kyle A. Nilson, 2017, Nucleic acids research.

Use of the nuclear walk-on methodology to determine sites of RNA polymerase II initiation and pausing and quantify nascent RNAs in cells.

D. Price, Kyle A. Nilson, C. B. Ball, 2019, Methods.

Editing of tRNA

Michael W. Gray, D. Price, David H. Price, 1998 .

Human Cytomegalovirus Infection Elicits Global Changes in Host Transcription by RNA Polymerases I, II, and III

D. Price, J. Meier, Benjamin M Spector, 2022, Viruses.

Nucleotide Resolution Comparison of Transcription of Human Cytomegalovirus and Host Genomes Reveals Universal Use of RNA Polymerase II Elongation Control Driven by Dissimilar Core Promoter Elements

D. Price, J. Meier, D. Luse, 2019, mBio.

Release of Positive Transcription Elongation Factor b (P-TEFb) from 7SK Small Nuclear Ribonucleoprotein (snRNP) Activates Hexamethylene Bisacetamide-inducible Protein (HEXIM1) Transcription*

B. Peterlin, D. Price, K. Fujinaga, 2014, The Journal of Biological Chemistry.

PKC phosphorylates HEXIM1 and regulates P-TEFb activity

B. Peterlin, M. Barborič, Qintong Li, 2012, Nucleic acids research.

Identification of a novel isoform of Cdk9.

D. Price, Sarah M. Shore, W. Maury, 2003, Gene.

Transient pausing by RNA polymerase II

D. Price, 2018, Proceedings of the National Academy of Sciences.

Cloning of a Drosophila cDNA with sequence similarity to human transcription factor RAP74.

J. Greenblatt, D. Price, Z. Burton, 1993, Nucleic Acids Research.

An activity necessary for in vitro transcription is a DNase inhibitor.

A. Sluder, A. Greenleaf, D. Price, 1987, Biochimie.

Zhi Xie and David H . Price Transcript Release Factor Unusual Nucleic Acid Binding Properties of Factor 2 , an RNA Polymerase II

D. Price, Zhi Xie, 1998 .

Regulation of RNA Polymerase II Elongation by c-Myc

D. Price, 2010, Cell.

Identification and purification of a yeast protein that affects elongation by RNA polymerase II.

D. Price, D. Chafin, T. J. Claussen, 1991, The Journal of biological chemistry.

Drosophila RNA polymerase II elongation factor DmS-II has homology to mouse S-II and sequence similarity to yeast PPR2.

D. Price, T. Marshall, H. Guo, 1990, Nucleic acids research.

Transcription | RNA Polymerase II Elongation Control in Eukaryotes

Hani S. Zaher, D. Price, 2021, Encyclopedia of Biological Chemistry III.

RNA Polymerase II Elongation Control in Eukaryotes

D. Price, 2004 .

A novel nucleotide incorporation activity implicated in the editing of mitochondrial transfer RNAs in Acanthamoeba castellanii.

D. Price, M. Gray, 1999, RNA.

Sirtuin 6 is required for the integrated stress response and resistance to inhibition of transcriptional cyclin-dependent kinases

Aaron E. Lampano, A. Hsieh, F. Notta, 2023, Science Translational Medicine.

Synthesis of U1 RNA in a DNA-dependent system from sea urchin embryos.

D. Price, W. Marzluff, Gilbert F. Morris, 1986, Proceedings of the National Academy of Sciences of the United States of America.

DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

M. Hollingsworth, D. Price, Pankaj Singh, 2023, bioRxiv.

Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.

Howard Y. Chang, Ryan A. Flynn, R. White, 2016, Molecular cell.

Runaway transcription

D. Price, Tiandao Li, Jiannan Guo, 2013, Genome Biology.