E. Newcomb

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Flavopiridol inhibits the Growth of GL261 Gliomas In Vivo: Implications for Malignant Glioma Therapy

Douglas C. Miller, D. Crișan, D. Zagzag, 2004, Cell cycle.

Flavopiridol Induces Mitochondrial-Mediated Apoptosis in Murine Glioma GL261 Cells via Release of Cytochrome c and Apoptosis Inducing Factor

Douglas C. Miller, D. Crișan, D. Zagzag, 2003, Cell cycle.

CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia

Iannis Aifantis, Michael L. Dustin, Jiri Zavadil, 2009, Nature.

Expression of cell cycle regulators p57(KIP2), cyclin D1, and cyclin E in epithelial ovarian tumors and survival.

H. Yee, A. Zeleniuch‐Jacquotte, E. Newcomb, 2001, Human pathology.

Flavopiridol: pleiotropic biological effects enhance its anti-cancer activity

E. Newcomb, 2004, Anti-cancer drugs.

Geldanamycin inhibits migration of glioma cells in vitro: A potential role for hypoxia‐inducible factor (HIF‐1α) in glioma cell invasion

D. Zagzag, E. Newcomb, D. Friedlander, 2003, Journal of cellular physiology.

Malignant mouse melanoma cells do not form tumors when mixed with cells of a non‐malignant subclone: Relationships between plasminogen activator expression by the tumor cells and the host's immune response

E. Newcomb, S. Silverstein, S. Silagi, 1978, Journal of cellular physiology.

Geldanamycin induces mitotic catastrophe and subsequent apoptosis in human glioma cells

D. Zagzag, E. Newcomb, C. Tamasdan, 2004, Journal of cellular physiology.

p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression

E. Newcomb, R. Silber, M. Potměšil, 1993 .

Expression of the cell cycle inhibitor p27KIP1 is a new prognostic marker associated with survival in epithelial ovarian tumors.

A. Zeleniuch‐Jacquotte, E. Newcomb, R. Demopoulos, 1999, The American journal of pathology.

Noscapine induces apoptosis in human glioma cells by an apoptosis-inducing factor-dependent pathway

D. Zagzag, E. Newcomb, Tona Schnee, 2008, Anti-cancer drugs.

Radiation Sensitivity of GL261 Murine Glioma Model and Enhanced Radiation Response by Flavopiridol

D. Zagzag, S. Formenti, B. Rosenstein, 2006, Cell cycle.

The geldanamycin analogue 17-allylamino-17-demethoxygeldanamycin inhibits the growth of GL261 glioma cells in vitro and in vivo

D. Zagzag, E. Newcomb, Tona Schnee, 2007, Anti-cancer drugs.

Advances in Brief p 53 Mutations in Nonastrocytic Human Brain Tumors '

P. Kleihues, H. Ohgaki, O. Wiestler, 2006 .

Treatment of pediatric brain tumors

Jeffrey C. Allen, E. Newcomb, M. Karajannis, 2008, Journal of cellular physiology.

Expression of p27KIP1 in human gliomas: relationship between tumor grade, proliferation index, and patient survival.

Douglas C. Miller, D. Zagzag, E. Newcomb, 2003, Human pathology.

The Combination of Ionizing Radiation and Peripheral Vaccination Produces Long-term Survival of Mice Bearing Established Invasive GL261 Gliomas

N. Kawashima, S. Demaria, W. McBride, 2006, Clinical Cancer Research.

Immunotherapy of pediatric brain tumor patients should include an immunoprevention strategy: a medical hypothesis paper

E. Newcomb, M. Jadus, N. Hoa, 2009, Journal of Neuro-Oncology.

HGF upregulates CXCR4 expression in gliomas via NF-κB: implications for glioma cell migration

D. Zagzag, E. Newcomb, Mine Esencay, 2010, Journal of Neuro-Oncology.

Geldanamycin induces G2 arrest in U87MG glioblastoma cells through downregulation of Cdc2 and cyclin B1.

D. Zagzag, E. Newcomb, N. Nomura, 2007, Biochemical pharmacology.

Antiangiogenic effects of noscapine enhance radioresponse for GL261 tumors.

W. McBride, D. Zagzag, S. Formenti, 2008, International journal of radiation oncology, biology, physics.

Oncogene activation and surface markers in mouse lymphomas induced by radiation and nitrosomethylurea.

J. J. Steinberg, J. Berman, A. Pellicer, 1986, Leukemia research.

N‐methylnitrosourea—lnduced Ki‐ras codon 12 mutations: Early events in mouse thymic lymphomas

E. Newcomb, W. Bayona, S. Pisharody, 1995, Molecular carcinogenesis.

raÃ Oncogenes and Phenotypic Staging in 7V-Methylnitrosourea- and 7-Irradiation-induced Thymic Lymphomas in C57BL/6J Mice1

J. J. Steinberg, A. Pellicer, E. Newcomb, 2006 .

Differential expression of the normal and mutated K-ras alleles in chemically induced thymic lymphomas.

A. Pellicer, M. Perucho, E. Newcomb, 1991, Cancer research.

p53 mutations in human malignant gliomas: comparison of loss of heterozygosity with mutation frequency.

E. Newcomb, M. Koslow, W. Bayona, 1992, Cancer research.

High frequency of p53 protein accumulation without p53 gene mutation in human juvenile pilocytic, low grade and anaplastic astrocytomas.

D. Miller, F. Lang, E. Newcomb, 1994, Oncogene.

Preferential Inactivation of the p53 Tumor Suppressor Pathway and Lack of EGFR Amplification Distinguish de novo High Grade Pediatric Astrocytomas from de novo Adult Astrocytomas

Douglas C. Miller, D. Miller, H. Yee, 2000, Brain pathology.

Pathogenesis of Burkitt lymphoma: Expression of an activated c-myc oncogene causes the tumorigenic conversion of EBV-infected human B lymphoblasts

E. Newcomb, L. Lombardi, R. Dalla-Favera, 1987, Cell.

p53 mutations in nonastrocytic human brain tumors.

P. Kleihues, H. Ohgaki, O. Wiestler, 1991, Cancer research.

Alterations of multiple tumor suppressor genes (p53 (17p13), p16INK4 (9p21), and DBM (13q14)) in B‐CELL chronic lymphocytic leukemia

E. Newcomb, S. Y. Lee, L. Rao, 1995, Molecular carcinogenesis.

Possible association of p53 codon 72 polymorphism with susceptibility to adult and pediatric high-grade astrocytomas.

Douglas C. Miller, Jeffrey C. Allen, E. Newcomb, 2005, Brain research. Molecular brain research.

Flavopiridol induces apoptosis in glioma cell lines independent of retinoblastoma and p53 tumor suppressor pathway alterations by a caspase-independent pathway.

Douglas C. Miller, M. Alonso, E. Newcomb, 2003, Molecular cancer therapeutics.

Radiotherapy Enhances Antitumor Effect of Anti-CD137 Therapy in a Mouse Glioma Model

N. Kawashima, S. Demaria, D. Zagzag, 2010, Radiation research.

A unique spectrum of p53 mutations in B‐cell chronic lymphocytic leukemia distinct from that of other lymphoid malignancies

E. Newcomb, S. Rouby, Anju Thomas, 1995, Molecular carcinogenesis.

Loss of Heterozygosity with Mutation Frequency p 53 Mutations in Human Malignant Gliomas : Comparison of Updated

E. Newcomb, M. Koslow, W. Bayona, 2006 .

Mutations in Human Malignant Gliomas : Comparison of Loss of Heterozygosity with Mutation Frequency 1

E. Newcomb, M. Koslow, W. Bayona, 2006 .

Green Fluorescent Protein Immunohistochemistry as a Novel Experimental Tool for the Detection of Glioma Cell Invasion In Vivo

Douglas C. Miller, L. Chiriboga, H. Yee, 2003, Brain pathology.

Caspase-dependent Activation of Calpain during Drug-induced Apoptosis*

E. Newcomb, D. Wood, 1999, The Journal of Biological Chemistry.

A comparative analysis of radiation- and virus-induced leukemias in BALB/c mice.

E. Newcomb, R. Binari, E. Fleissner, 1985, Virology.

Relationship of antigenicity of melanoma cells grown in 5-bromodeoxyuridine to reduced tumorigenicity.

E. Newcomb, M. Weksler, S. Silagi, 1974, Cancer research.

Chemosensitivity of lymphocytes from patients with B-cell chronic lymphocytic leukemia to chlorambucil, fludarabine, and camptothecin analogs.

E. Newcomb, M. Mani, R. Silber, 1994, Blood.

P53 gene mutations in lymphoid diseases and their possible relevance to drug resistance.

E. Newcomb, 1995, Leukemia & lymphoma.

p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression.

E. Newcomb, R. Silber, A. Thomas, 1993, Blood.

Drug-induced apoptosis in B-cell chronic lymphocytic leukemia: relationship between p53 gene mutation and bcl-2/bax proteins in drug resistance.

John Calvin Reed, S. Krajewski, E. Newcomb, 1996, Oncogene.

Comparative analysis and anatomic distribution of ras p21, IL-2R, and MEL-14 in malignant and hyperplastic murine thymus.

A. Pellicer, E. Newcomb, C. Cordon, 1990, The American journal of pathology.

Incidence of p14ARF gene deletion in high-grade adult and pediatric astrocytomas.

D. Miller, M. Alonso, E. Newcomb, 2000, Human pathology.

Transformation and plasmacytoid differentiation of EBV-infected human B lymphoblasts by ras oncogenes.

G. Inghirami, G. Dotto, E. Newcomb, 1989, Science.

Neutron radiation can activate K-ras via a point mutation in codon 146 and induces a different spectrum of ras mutations than does gamma radiation

A. Pellicer, E. Newcomb, S. Sloan, 1990, Molecular and cellular biology.

ras oncogenes and phenotypic staging in N-methylnitrosourea- and gamma-irradiation-induced thymic lymphomas in C57BL/6J mice.

J. J. Steinberg, A. Pellicer, E. Newcomb, 1988, Cancer research.

Assignment of the human B-cell-derived (BCD1) proto-oncogene to 10p14-p15.

P. H. Rao, E. Newcomb, S. el Rouby, 1997, Genomics.

p53 mutations in C57BL/6J murine thymic lymphomas induced by gamma-irradiation and N-methylnitrosourea.

E. Newcomb, W. Bayona, O. Brathwaite, 1992, Cancer research.

Co‐cultivation of tumorigenic mouse melanoma cells with cells of a non‐tumorigenic subclone inhibits plasminogen activator expression by the melanoma cells

J. Christman, E. Newcomb, S. Silverstein, 1978, Journal of cellular physiology.

Analysis of alterations of oncogenes and tumor suppressor genes in chronic lymphocytic leukemia.

G. Gaidano, L. Baldini, A. Neri, 1994, The American journal of pathology.

Radiation and chemical activation of ras oncogenes in different mouse strains.

A. Pellicer, E. Newcomb, S. Sloan, 1989, Environmental health perspectives.

Single-base mutations associated with mouse lymphomas.

J. Berman, A. Pellicer, E. Newcomb, 1986, Basic life sciences.

ras activation in human tumors and in animal model systems.

A. Pellicer, J. León, E. Newcomb, 1991, Environmental health perspectives.

Knock down of HIF-1α in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres

Jiri Zavadil, J. Zavadil, D. Zagzag, 2010, Molecular Cancer.

Cleavage of Bax enhances its cell death function.

E. Newcomb, D. Wood, 2000, Experimental cell research.

Suppression of melanoma cell tyrosinase activity and tumorigenicity after incorporation of bromouracil for one or two cell divisions

J. Wrathall, E. Newcomb, S. Silagi, 1975, Journal of cellular physiology.

E. Newcomb, S. Silverstein, J. Christman, 1975, Proceedings of the National Academy of Sciences of the United States of America.

Clonal evolution of N-methylnitrosourea-induced C57BL/6J thymic lymphomas by analysis of multiple genetic alterations.

E. Newcomb, 1997, Leukemia research.

The neuraminidase of measles virus.

E. Newcomb, C. Howe, L. T. Lee, 1969, Biochemical and biophysical research communications.

Angiogenesis in Gliomas: Imaging and Experimental Therapeutics

D. Zagzag, E. Newcomb, M. Law, 2005, Brain pathology.

The Murine GL261 Glioma Experimental Model to Assess Novel Brain Tumor Treatments

D. Zagzag, E. Newcomb, 2009 .

Pathways leading to glioblastoma multiforme: a molecular analysis of genetic alterations in 65 astrocytic tumors.

M Koslow, D. Miller, F. Lang, 1994, Journal of neurosurgery.

radiation.of ras mutations than does gamma mutation in codon 146 and induces a different Neutron radiation can activate K-ras via a point

A. Pellicer, E. Newcomb, S. Sloan, 2013 .

p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia.

G. Gaidano, G. Inghirami, A. Neri, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Tumour-suppressor activity of H19 RNA

Benjamin Tycko, Yue Hao, B. Tycko, 1993, Nature.

Tumor antigen precursor protein profiles of adult and pediatric brain tumors identify potential targets for immunotherapy

J. Wisoff, Jeffrey C. Allen, D. Zagzag, 2008, Journal of Neuro-Oncology.

Correlative Immunohistochemistry and Molecular Genetic Study of the Inactivation of the p16INK4A Genes in Astrocytomas

Douglas C. Miller, E. Newcomb, L. Rao, 1997, Diagnostic molecular pathology : the American journal of surgical pathology, part B.

Microsatellite instability occurs in distinct subtypes of pediatric but not adult central nervous system tumors.

D. Miller, R. Hamelin, M. Alonso, 2001, Cancer research.

Hypoxia- and vascular endothelial growth factor-induced stromal cell-derived factor-1alpha/CXCR4 expression in glioblastomas: one plausible explanation of Scherer's structures.

L. Chiriboga, H. Yee, D. Zagzag, 2008, The American journal of pathology.

Frequent homozygous deletions of D13S218 on 13q14 in B-cell chronic lymphocytic leukemia independent of disease stage and retinoblastoma gene inactivation.

E. Newcomb, A. Thomas, M. Potměšil, 1995, Cancer research.

Bax cleavage is mediated by calpain during drug-induced apoptosis

John Calvin Reed, R. Beavis, E. Newcomb, 1998, Oncogene.

Noscapine inhibits hypoxia-mediated HIF-1alpha expression andangiogenesis in vitro: a novel function for an old drug.

D. Zagzag, E. Newcomb, Tona Schnee, 2006, International journal of oncology.

Identification of a specific marker chromosome early in tumor development in gamma-irradiated C57BL/6J mice.

A. Pellicer, E. Newcomb, L. McMorrow, 1988, Leukemia.

Angiogenesis in Gliomas: Biology and Molecular Pathophysiology

D. Zagzag, E. Newcomb, M. Law, 2005, Brain pathology.

bcl-2 protein expression in astrocytomas in relation to patient survival and p53 gene status

Douglas C. Miller, E. Newcomb, H. Cohen, 1997, Acta Neuropathologica.

Flavopiridol downregulates hypoxia-mediated hypoxia-inducible factor-1alpha expression in human glioma cells by a proteasome-independent pathway: implications for in vivo therapy.

Douglas C. Miller, M. Fowkes, D. Zagzag, 2005, Neuro-oncology.

A Correlative Study of p53 Protein Alteration and p53 Gene Mutation in Glioblastoma Multiforme

Douglas C. Miller, W. Madonia, F. Lang, 1993, Brain pathology.

Therapeutic targets in malignant glioblastoma microenvironment.

Mary Helen Barcellos-Hoff, Ashwatha Narayana, M. Barcellos-Hoff, 2009, Seminars in radiation oncology.

Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion

H. Yee, D. Zagzag, E. Newcomb, 2006, Laboratory Investigation.

Multistage carcinogenesis in murine thymocytes: involvement of oncogenes, chromosomal imbalances and T cell growth factor receptor.

A. Pellicer, E. Newcomb, M. Corominas, 1989, Anticancer research.

Survival of Patients with Glioblastoma Multiforme is not Influenced by Altered Expression of P16, P53, EGFR, MDM2 or Bcl‐2 Genes

Douglas C. Miller, E. Newcomb, H. Cohen, 1998, Brain pathology.

Identification of Glutathione S-transferase (GST) Polymorphisms in Brain Tumors and Association with Susceptibility to Pediatric Astrocytomas

Douglas C. Miller, M. Alonso, Jeffrey C. Allen, 2002, Journal of Neuro-Oncology.

Clonal Analysis of IgM+ CD5+ CLL B Cells a

G. Inghirami, P. Casali, E. Newcomb, 1995, Annals of the New York Academy of Sciences.

HIF-1 Regulation of Chemokine Receptor Expression

D. Zagzag, E. Newcomb, 2009 .

Expression of the Cell Cycle Inhibitor p27 KIP1 Is a New Prognostic Marker Associated with Survival in Epithelial Ovarian Tumors

A. Zeleniuch‐Jacquotte, E. Newcomb, R. Demopoulos, 1998 .

p53 mutations in B-cell chronic lymphocytic leukemia.

E. Newcomb, W. Bayona, S. Pisharody, 1992, Current topics in microbiology and immunology.

Overexpression and activation of epidermal growth factor receptor in hemangioblastomas

D. Zagzag, E. Newcomb, Gregory J. Chen, 2010, Journal of Neuro-Oncology.

Downregulation of major histocompatibility complex antigens in invading glioma cells: stealth invasion of the brain

S. Demaria, L. Chiriboga, H. Yee, 2005, Laboratory Investigation.

Growth studies of parainfluenza virus (type 2)

E. Newcomb, C. Howe, S. Milliken, 2005, Archiv für die gesamte Virusforschung.

Alterations of Multiple Tumor Suppressor Genes @ 53 ( 17 pl 3 ) , pl 6 ‘ Chronic Lymphocytic Leukemia NK 4 ( 9 p 21 ) , and DBM ( 13 q 14 ) ) in B-Cell

E. Newcomb, L. Rao, Seung Y. Lee, 2006 .

REGULATORY INFLUENCE OF THYMOPENTIN ON SPLENIC T CELL SETS OF THYMECTOMIZED AND AGED MICE1,2

E. Newcomb, E. Boyse, G. Goldstein, 1985, Transplantation.

Identification of Bcd, a novel proto-oncogene expressed in B-cells.

E. Newcomb, S. Rouby, 1996, Oncogene.

Hypoxia- and vascular endothelial growth factor-induced stromal cell-derived factor-1alpha/CXCR4 expression in glioblastomas: one plausible explanation of Scherer's structures.

L. Chiriboga, H. Yee, D. Zagzag, 2008, The American journal of pathology.

Flavopiridol downregulates hypoxia-mediated hypoxia-inducible factor-1alpha expression in human glioma cells by a proteasome-independent pathway: implications for in vivo therapy.

M. Fowkes, D. Zagzag, E. Newcomb, 2005, Neuro-oncology.