H. Nakano

发表

UCN-01 and UCN-02, new selective inhibitors of protein kinase C. I. Screening, producing organism and fermentation.

I. Takahashi, K. Asano, I. Kawamoto, 1989, The Journal of antibiotics.

How Does the FMO Method Help in Studying Viruses and Their Binding to Receptors

Tohru Suzuki, H. Nakano, M. Kiso, 2009 .

Ab initio fragment molecular orbital studies of influenza virus hemagglutinin–sialosaccharide complexes toward chemical clarification about the virus host range determination

Tohru Suzuki, H. Nakano, M. Kiso, 2008, Glycoconjugate Journal.

Ab initio base fragment molecular orbital studies of influenza viral hemagglutinin HA1 full-domains in complex with sialoside receptors

Tohru Suzuki, H. Nakano, M. Kiso, 2008, Journal of molecular and genetic medicine : an international journal of biomedical research.

Influenza viral hemagglutinin complicated shape is advantageous to its binding affinity for sialosaccharide receptor.

Yoshihiro Kawaoka, Hirofumi Nakano, Tomohiro Hashimoto, 2007, Biochemical and biophysical research communications.

Why does avian influenza A virus hemagglutinin bind to avian receptor stronger than to human receptor? Ab initio fragment molecular orbital studies.

Hirofumi Nakano, Tomohiro Hashimoto, Tohru Suzuki, 2006, Biochemical and biophysical research communications.

Sertraline, chlorprothixene, and chlorpromazine characteristically interact with the REST-binding site of the corepressor mSin3, showing medulloblastoma cell growth inhibitory activities

Y. Fukunishi, H. Nakano, Y. Nishimura, 2018, Scientific Reports.

Potent and Specific Inhibitors of Protein Kinase C of Microbial Origin

T. Tamaoki, H. Nakano, 1990, Bio/Technology.

Identification of Ras farnesyltransferase inhibitors by microbial screening.

F. Tamanoi, S. Akinaga, H. Nakano, 1993, Proceedings of the National Academy of Sciences of the United States of America.

In vitro tyrosine phosphorylation studies on RAS proteins and calmodulin suggest that polylysine-like basic peptides or domains may be involved in interactions between insulin receptor kinase and its substrate.

H. Nakano, Y. Fujita-Yamaguchi, J. McDonald, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Identification and Characterization of a Novel NADPH Oxidase 1 (Nox1) Inhibitor That Suppresses Proliferation of Colon and Stomach Cancer Cells.

Y. Urano, H. Nakano, T. Kamata, 2018, Biological & pharmaceutical bulletin.

Calphostins (UCN-1028), novel and specific inhibitors of protein kinase C. I. Fermentation, isolation, physico-chemical properties and biological activities.

T. Tamaoki, H. Nakano, M. Morimoto, 1989, The Journal of antibiotics.

Calphostin (UCN1028) and calphostin related compounds, a new class of specific and potent inhibitors of protein kinase C.

S. Akinaga, I. Takahashi, T. Tamaoki, 1990, Advances in second messenger and phosphoprotein research.

Potent selective inhibition of 7-O-methyl UCN-01 against protein kinase C.

I. Takahashi, T. Tamaoki, H. Nakano, 1990, The Journal of pharmacology and experimental therapeutics.

Inhibition of protein kinase C by calphostin C is light-dependent.

J. Howbert, I. Takahashi, T. Tamaoki, 1991, Biochemical and biophysical research communications.

Production of structured lipid containing docosahexaenoic and caprylic acids using immobilized Rhizopus delemar lipase

Y. Shimada, A. Sugihara, Y. Tominaga, 1996 .

Interconversion and stability of duocarmycins, a new family of antitumor antibiotics: correlation to their cytotoxic and antimicrobial activities in vitro.

H. Nakano, K. Takahashi, M. Ichimura, 1993, Oncology research.

Duocarmycin SA, a new antitumor antibiotic from Streptomyces sp.

I. Kawamoto, H. Nakano, K. Takahashi, 1990, The Journal of antibiotics.

Characterization of a duocarmycin-DNA adduct-recognizing protein in cancer cells.

K. Yano, T. Mizukami, A. Asai, 1999, Cancer research.

Interaction of radicicol with members of the heat shock protein 90 family of molecular chaperones.

Sreenath V. Sharma, L. Neckers, S. Akinaga, 1999, Molecular endocrinology.

UCS15A, a non-kinase inhibitor of Src signal transduction

Sreenath V. Sharma, T. Tamaoki, H. Nakano, 2001, Oncogene.

Mouse N-acetylgalactosamine 4-sulfotransferases-1 and -2. Molecular cloning, expression, chromosomal mapping and detection of their activity with GalNAcbeta1-4GlcNAcbeta1-octyl.

Y. Matsuda, H. Nakano, Toshihiko Sawada, 2003, Journal of biochemistry.

Synthesis of sulfated phenyl 2-acetamido-2-deoxy-D-galactopyranosides. 4-O-Sulfated phenyl 2-acetamido-2-deoxy-beta-D-galactopyranoside is a competitive acceptor that decreases sulfation of chondroitin sulfate by N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase.

H. Nakano, Toshihiko Sawada, K. Kimata, 2005, Carbohydrate research.

Conformational Study of α‐N‐Acetyl‐D‐Neuraminic Acid by Density Functional Theory

H. Nakano, M. Kiso, Toshihiko Sawada, 2006 .

In vitro biosynthesis of galactans by membrane-bound galactosyltransferase from radish (Raphanus sativus L.) seedlings

H. Nakano, P. Kováč, Y. Hashimoto, 2003, Planta.

Purification and Characterization of a Novel α-Glucuronidase from Aspergillus niger Specific for O-α-D-Glucosyluronic Acid α-D-Glucosiduronic Acid

H. Nakano, T. Kiryu, T. Kiso, 2005 .

Radicicol inhibits tyrosine phosphorylation of the mitotic Src substrate Sam68 and retards subsequent exit from mitosis of Src-transformed cells.

H. Nakano, S. Sharma, I. Pillay, 1996, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Induction of mammalian topoisomerase II dependent DNA cleavage by nonintercalative flavonoids, genistein and orobol.

H. Nakano, Y. Yamashita, S. Kawada, 1990, Biochemical pharmacology.

Molecular Cloning and Characterization of GalNAc 4-Sulfotransferase Expressed in Human Pituitary Gland*

H. Nakano, Toshihiko Sawada, T. Okuda, 2000, The Journal of Biological Chemistry.

Oxidative coupling reaction of arbutin and gentisate catalyzed by horseradish peroxidase

H. Nakano, M. Shizuma, T. Terai, 2007 .

One-pot synthesis of glycosyl poly(arbutin) by enzymatic glycosylation followed by polymerization with peroxidase

H. Nakano, M. Shizuma, T. Kiryu, 2005 .

GILVOCARCINS, NEW ANTITUMOR ANTIBIOTICS

H. Nakano, M. Morimoto, F. Tomita, 1981 .

Gilvocarcins, new antitumor antibiotics. 1. Taxonomy, fermentation, isolation and biological activities.

H. Nakano, M. Morimoto, F. Tomita, 1981, The Journal of antibiotics.

hnRNP L enhances sensitivity of the cells to KW‐2189

K. Yano, H. Kato, N. Saijo, 2004, International journal of cancer.

An effect of the ionic radii of lanthanide(III) ions on the structure and catalytic properties of chiral Schiff base-lanthanide(III) complexes

H. Nakano, S. Kano, N. Baba, 2003 .

Senacarcin A, a new antitumor antibiotic produced by Streptomyces endus subsp. aureus.

H. Nakano, M. Morimoto, F. Tomita, 1982, The Journal of antibiotics.

Optimization of Lactobionic Acid Production by Acetobacter orientalis Isolated from Caucasian Fermented Milk, “Caspian Sea Yogurt”

H. Nakano, Takashi Kimura, A. Masuyama, 2012, Bioscience, biotechnology, and biochemistry.

Purification and properties of urease from Brevibacterium ammoniagenes

H. Nakano, Yasuto Watanabe, S. Takenishi, 1984 .

Different Modes of Cell‐killing Action between DNA Topoisomerase I and II Inhibitors Revealed by Kinetic Analysis

H. Nakano, J. Mitsuhashi, M. Inaba, 1994, Japanese journal of cancer research : Gann.

Suppression of RAS and MOS transformation by radicicol.

H. Nakano, S. Sharma, J. Zhao, 1995, Oncogene.

Synthesis of Novel Heterobranched β-Cyclodextrins Having β-D-N-Acetylglucosaminyl-Maltotriose on the Side Chain

H. Nakano, A. Ikuta, Y. Nishi, 2005 .

Friedel-Crafts reactionin fluorous fluids

H. Nakano, T. Kitazume, 1999 .

Organic reactions without an organic medium. Utilization of perfluorotriethylamine as a reaction medium

H. Nakano, T. Kitazume, 1999 .

Targeting AMAP 1 and cortactin binding bearing an atypical src homology 3 proline interface for prevention of breast cancer invasion and metastasis

H. Hosaka, T. Ikegami, H. Wada, 2006 .

Purification and Characterization of a Carbohydrate:Acceptor Oxidoreductase from Paraconiothyrium sp. That Produces Lactobionic Acid Efficiently

H. Nakano, T. Kiryu, T. Kiso, 2008, Bioscience, biotechnology, and biochemistry.

Purification and characterization of a novel β-glucosidase from Clavibacter michiganense that hydrolyzes glucosyl ester linkage in steviol glycosides

H. Nakano, S. Kitahata, T. Kiso, 1998 .

Purification and characterization of an exo-1,4-beta-galactanase from a strain of Bacillus subtilis.

H. Nakano, S. Kitahata, Y. Watanabe, 1990, European journal of biochemistry.

Purification and Properties of Two Galactanases from Penicillium citrinum

H. Nakano, Yasuto Watanabe, S. Takenishi, 1985 .

Constituents of a fern, Davallia mariesii Moore. I. Isolation and structures of davallialactone and a new flavanone glucuronide.

J. H. Park, T. Tamaoki, H. Nakano, 1990, Chemical & pharmaceutical bulletin.

Development of a potent and selective FLT3 kinase inhibitor by systematic expansion of a non-selective fragment-screening hit.

H. Nakano, T. Nagano, H. Kojima, 2016, Bioorganic & medicinal chemistry letters.

UCE6, a new antitumor antibiotic with topoisomerase I-mediated DNA cleavage activity produced by actinomycetes: producing organism, fermentation, isolation and biological activity.

T. Ashizawa, H. Nakano, Y. Yamashita, 1997, The Journal of antibiotics.

Induction of topoisomerase II-mediated DNA cleavage by the plant naphthoquinones plumbagin and shikonin

H. Nakano, Y. Yamashita, M. Nagashima, 1992, Antimicrobial Agents and Chemotherapy.

UCT4B, a new antitumor antibiotic with topoisomerase II mediated DNA cleavage activity, from Streptomyces sp.

H. Nakano, K. Gomi, Y. Yamashita, 1992, The Journal of antibiotics.

Antitumor quinolones with mammalian topoisomerase II mediated DNA cleavage activity.

T. Ashizawa, H. Nakano, M. Morimoto, 1992, Cancer research.

Induction of mammalian DNA topoisomerase I and II mediated DNA cleavage by saintopin, a new antitumor agent from fungus.

H. Nakano, Y. Yamashita, S. Kawada, 1991, Biochemistry.

Induction of a heat-stable topoisomerase II-DNA cleavable complex by nonintercalative terpenoides, terpentecin and clerocidin.

H. Nakano, Y. Yamashita, S. Kawada, 1991, Cancer research.

Saintopin, a new antitumor antibiotic with topoisomerase II dependent DNA cleavage activity, from Paecilomyces.

H. Nakano, Y. Yamashita, K. Takahashi, 1990, The Journal of antibiotics.

Biosynthesis of Corynecins by Corynebacterium hydrocarboclastus: On the Origin of the N-Acyl Group

H. Nakano, F. Tomita, Takeo Suzuki, 1976 .

Expression of intact Ki-ras p21 protein in Escherichia coli.

T. Mizukami, M. Perucho, T. Tamaoki, 1985, Biochemical and biophysical research communications.

DNA strand scission by the novel antitumor antibiotic leinamycin.

H. Nakano, M. Hara, Y. Saitoh, 1990, Biochemistry.

Leinamycin, a new antitumor antibiotic from Streptomyces: producing organism, fermentation and isolation.

K. Asano, I. Kawamoto, H. Nakano, 1989, The Journal of antibiotics.

Purification of docosahexaenoic acid by selective esterification of fatty acids from tuna oil with Rhizopus delemar lipase

Y. Shimada, A. Sugihara, Y. Tominaga, 1997 .

The rhodium(II) acetate-catalyzed reaction of diacyldiazomethanes with isothiocyanates : formation of 2-thioxo-2H-1,3-oxazin-4(3H)-one

H. Nakano, T. Ibata, 1993 .

Purification and Some Properties of a β-Glucosidase from Flavobacterium johnsonae

H. Nakano, S. Kitahata, T. Kiso, 2000, Bioscience, biotechnology, and biochemistry.

Formation of Transfer Products from Soybean Arabinogalactan and Glycerol by Galactanase from Penicillium citrinum

H. Nakano, Yasuto Watanabe, S. Takenishi, 1988 .

Action of Galactanase from Penicillium citrinum on o-Nitrophenyl-β-D-galactopyranoside(Biological Chemistry)

H. Nakano, Yasuto Watanabe, S. Takenishi, 1986 .

Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C.

T. Tamaoki, H. Nakano, M. Morimoto, 1989, Biochemical and biophysical research communications.

The Lewis acid-promoted reactions of o-phthaladehyde with trialkyl phosphites: Formation of 1-dialkoxyphosphorylisobenzofuran

H. Nakano, K. Yamana, 1996 .

Duocarmycins, new antitumor antibiotics produced by Streptomyces; producing organisms and improved production.

H. Nakano, K Takahashi, K. Takahashi, 1991, The Journal of antibiotics.

Duocarmycin A, a new antitumor antibiotic from Streptomyces.

K. Asano, I. Kawamoto, H. Nakano, 1988, The Journal of antibiotics.

DC89-A1, a new antitumor antibiotic from Streptomyces.

K. Asano, I. Kawamoto, H. Nakano, 1988, The Journal of antibiotics.

Synthesis of polycyclic phosphonates via an intramolecular Diels-Alder reaction of 2-benzoylbenzalaldehyde and alkenyl phosphites

H. Nakano, K. Yamana, 2019, Heterocyclic Communications.

UCN-01, a selective inhibitor of protein kinase C from Streptomyces.

I. Takahashi, K. Asano, H. Nakano, 1987, The Journal of antibiotics.

DC 107, a novel antitumor antibiotic produced by a Streptomyces sp.

K. Asano, I. Kawamoto, H. Nakano, 1989, The Journal of antibiotics.

Rational evolution of a novel type of potent and selective proviral integration site in Moloney murine leukemia virus kinase 1 (PIM1) inhibitor from a screening-hit compound.

S. Yokoyama, H. Nakano, T. Nagano, 2012, Journal of medicinal chemistry.

The Rhodium(II) Acetate-Catalyzed Reaction of Alkenyl and Alkynyl α-Diazoacetates with Thioketene

H. Nakano, T. Ibata, 1995 .

Formation of 2-Imino-1,3-oxathioles and 2(3H)-Oxazolethione by the Rhodium(II) Acetate-Catalyzed Reaction of α-Diazocarbonyl Compounds with Isothiocyanates

H. Nakano, T. Ibata, 1992 .

Stereoselective synthesis of trifluoromethylated compounds via Johnson-Claisen and Eshenmoser-Claisen rearrangements

H. Nakano, T. Kitazume, T. Konno, 1997 .

UCH9, a new antitumor antibiotic produced by Streptomyces. II. Structure elucidation of UCH9 by mass and NMR spectroscopy.

H. Nakano, Y. Yamashita, H. Ogawa, 1998, The Journal of antibiotics.

UCH9, a new antitumor antibiotic produced by Streptomyces: I. Producing organism, fermentation, isolation and biological activities.

T. Ashizawa, H. Nakano, Y. Yamashita, 1998, The Journal of antibiotics.

Pyrronamycin A and B, novel antitumor antibiotics containing pyrrole-amide repeating unit, produced by Streptomyces sp.

K. Ochiai, T. Ashizawa, T. Mizukami, 2000, The Journal of antibiotics.

Hydrolysis of β-glucosyl ester linkage of p-hydroxybenzoyl β-d-glucose, a chemically synthesized glucoside, by β-glucosidases

H. Nakano, S. Kitahata, S. Miyoshi, 2000 .

Formation and Reaction of Carbonyl Ylides. Reactions of 1-Methoxy-2-benzopyrylium-4-olate with Isothiocyanates.

H. Nakano, T. Ibata, H. Tamura, 1992 .

Syntheses and properties of tertiary peptide bond-containing polypeptides.

H. Nakano, K. Ishikawa, M. Narita, 2009 .

Creation of Customized Bioactivity within a 14-Membered Macrolide Scaffold: Design, Synthesis, and Biological Evaluation Using a Family-18 Chitinase.

Satoshi Omura, Shuichi Hirono, Yoshifumi Saito, 2015, Journal of medicinal chemistry.

Preparation of branched cyclomaltoheptaose with 3-O-α-L-fucopyranosyl-α-D-mannopyranose and changes in fucosylation of HCT116 cells treated with the fucose-modified cyclomaltoheptaose.

Yuko Shirai, H. Nakano, E. Miyoshi, 2013, Carbohydrate research.

Purification of γ-linolenic acid from borage oil by a two-step enzymatic method

Y. Shimada, A. Sugihara, Y. Tominaga, 1997 .

Acceptor Specificity of Cyclodextrin Glycosyltransferase from Bacillus stearothermophilus and Synthesis of α-D-Glucosyl O-β-D-galactosyl-(1→4)-β-D-glucoside

H. Nakano, K. Fujita, K. Koizumi, 1992 .

Constituents of a Fern, Davallia mariesii MOORE. II. Identification and 1H- and 13C-Nuclear Magnetic Resonance Spectra of Procyanidin B-5, Epicatechin-(4β→8)-epicatechin-(4β→6)-epicatechin, and Epicatechin-(4β→6)-epicatechin-(4β→8)-epicatechin-(4β→6)-epicatechin

T. Tamaoki, H. Nakano, Y. Tezuka, 1992 .

Hypericin and pseudohypericin specifically inhibit protein kinase C: possible relation to their antiretroviral activity.

I. Takahashi, T. Tamaoki, H. Nakano, 1989, Biochemical and biophysical research communications.

Constituents of a Fern, Davallia mariesii MOORE. V.Isolation and Structures of Davallin, a New Tetrameric Proanthocyanidin, and Two New Phenolic Glycosides

T. Tamaoki, H. Nakano, Y. Tezuka, 1993 .

Purification and Characterization of a New Type of α-Glucosidase from Paecilomyces lilacinus That Has Transglucosylation Activity to Produce α-1,3-and α-1,2-Linked Oligosaccharides

H. Nakano, S. Kitahata, T. Konda, 2003 .

Purification and Characterization of a New Type of α-Glucosidase from Paecilomyces lilacinus That Has Transglucosylation Activity to Produce α-1,3- and α-1,2-Linked…

H. Nakano, S. Kitahata, T. Konda, 2003 .

4-アミノ安息香酸エチルエステル標識化法を用いたα-グルコオリゴ糖結合位置異性体の分析

H. Nakano, K. Ikura, S. Kitahata, 2002 .

Constituents of a Fern, Davallia mariesii MOORE. III. Revised Structure and Absolute Configuration of Davallialactone

T. Tamaoki, H. Nakano, Y. Tezuka, 1992 .

Inhibitors of DNA topoisomerase I and II isolated from the Coptis rhizomes.

T. Mizukami, H. Nakano, Y. Yamashita, 1995, Planta medica.

UCE1022, a new antitumor antibiotic with topoisomerase I mediated DNA cleavage activity, from Paecilomyces.

H. Nakano, K. Gomi, Y. Yamashita, 1993, The Journal of antibiotics.

Biological Production of Lactobionic Acid for Food

H. Nakano, D. Koma, Shigemitsu Tanaka, 2016 .

Biocatalytic Production of Lactobionic Acid

H. Nakano, T. Kiryu, T. Kiso, 2010 .

Production of Calcium Lactobionate by a Lactose-oxidizing Enzyme from Paraconiothyrium sp . KD3

H. Nakano, T. Kiryu, T. Kiso, 2008 .

Microbial Conversion of Lactose to Lactobionic Acid by Resting Cells of Burkholderia cepacia No . 24

Y. Shimada, H. Nakano, S. Kitahata, 2006 .

Microbial production of lactobionic acid by Burkholderia cepacia

H. Nakano, S. Kitahata, H. Murakami, 2004 .

Screening of Lactobionic Acid Producing Microorganisms

H. Nakano, H. Yoshizumi, S. Kitahata, 2002 .

Formation of Trehalose and Its 2-Deoxy Analogs through Condensation by a Trehalase from Lobosphaera sp.

H. Nakano, M. Moriwaki, S. Kitahata, 1994 .

Enzymatic Synthesis of (+)Catechin-α-glucoside and Its Effect on Tyrosinase Activity

H. Nakano, S. Murao, A. Hirota, 1993 .

Davallioside A and B, novel flavan-3-ol derivatives with a γ-lactam, from the rhizomes of Davallia mariesii Moore.

H. Nakano, Y. Tezuka, C. Cui, 1990 .

Transglycosylation of hydroquinone and epicatechin by beta-fructofuranosidase from Arthrobacter sp

H. Nakano, K. Fujita, S. Kitahata, 2002 .

Lipase-catalyzed esterification of mono- and oligoglycosides with various fatty acids

Y. Tominaga, H. Nakano, S. Kitahata, 1994 .

Syntheses of glucosides with trimethylolpropane and two related polyol moieties by cyclodextrin glucanotransferase and their esterification by lipase

Y. Tominaga, H. Nakano, S. Kitahata, 1992 .

The reversible DNA-alkylating activity of duocarmycin and its analogues

Hirofumi Nakano, Akira Asai, Satoru Nagamura, 1994, Nucleic Acids Res..

Covalent modification and single-strand scission of DNA by a new antitumor antibiotic kapurimycin A3.

H. Nakano, M. Hara, M. Yoshida, 1990, Biochemistry.

Flexibility of Glycosidases in Substrate Specificity?-Their Possible Application to the Synthesis of UnusualOligosaccharides and Glycosides-

H. Nakano, S. Kitahata, T. Kiso, 2000 .

Galactosylation of Thiol Group by β-Galactosidase

H. Nakano, S. Kitahata, M. Shizuma, 2000 .

Application of cyclodextrin glucanotransferase to the synthesis of useful oligosaccharides and glycosides.

H. Nakano, C. Hou, S. Kitahata, 2005 .

Synthesis of glycosyl glycerol by cyclodextrin glucanotransferases.

H. Nakano, M. A. Manan, T. Tomita, 2003, Journal of bioscience and bioengineering.

Inhibition of β-Fructofuranosidases and α-Glucosidases by Synthetic Thio-fructofuranoside

H. Nakano, K. Fujita, S. Kitahata, 2003 .

Synthesis of 2-deoxy-glucooligosaccharides through condensation of 2-deoxy-D-glucose by glucoamylase and alpha-glucosidase.

H. Nakano, H. Yoshizumi, K. Fujita, 1995, Bioscience, biotechnology and biochemistry.

Chemical synthesis of 4-azido-β-galactosamine derivatives for inhibitors of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase

H. Nakano, K. Hidari, K. Yamana, 2018, Glycoconjugate Journal.

FERMENTATION , ISOLATION , PHYSICO-CHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITIES

T. Tamaoki, H. Nakano, T. Iida, 2006 .

Purification and some properties of cell-bound α-galactosidase from Candida guilliermondii H-404

H. Nakano, H. Yoshizumi, K. Ikura, 1996 .

Substrate Specificity of Several β-Galactosidases toward a Series of β-1, 4-Linked Galactooligosaccharides

H. Nakano, Yasuto Watanabe, S. Takenishi, 1987 .

Transglycosylation of Mogroside V, a Triterpene Glycoside in Siraitia grosvenori, by Cyclodextrin Glucanotransferase and Improvement of the Qualities of Sweetness

H. Nakano, S. Kitahata, M. Shizuma, 2005 .

Hydrolysis of β-Galactosyl Ester Linkage by β-Galactosidases

H. Nakano, S. Kitahata, T. Terai, 2000 .

Synthesis of Useful Glycosides by Cyclodextrin Glucanotransferases and Glycosidases

H. Nakano, T. Kiso, 2009 .

Formation and Molecular Structure of the 2 : 1-Adducts of 1-Alkoxy-2-benzopyrylium-4-olates with Carbon Disulfide

H. Nakano, T. Ibata, H. Tamura, 1991 .

Sapurimycin, new antitumor antibiotic produced by Streptomyces. Producing organism, fermentation, isolation and biological properties.

T. Ashizawa, H. Nakano, K. Gomi, 1991, The Journal of antibiotics.

The kapurimycins, new antitumor antibiotics produced by Streptomyces. Producing organism, fermentation, isolation and biological activities.

H. Nakano, K. Gomi, M. Hara, 1990, The Journal of antibiotics.

Formation of 2-Methylene-1,3-oxathiole Derivatives in the Rhodium(II) Acetate-Catalyzed Reaction of α -Diazocarbonyl Compounds with Carbon Disulfide

H. Nakano, T. Ibata, 2009 .

Formation of 1,3-Oxathiole-2-thione and 1,2,4-Trithiolane Derivatives by the Catalytic Reaction of α-Diazocarbonyl Compounds with Carbon Disulfide

H. Nakano, T. Ibata, 1990 .

Targeting of the protein chaperone, HSP90, by the transformation suppressing agent, radicicol

Sreenath V. Sharma, H. Nakano, T. Agatsuma, 1998, Oncogene.

DC92-B, a new antitumor antibiotic from Actinomadura.

T. Ashizawa, K. Asano, I. Kawamoto, 1988, The Journal of antibiotics.

ANTIBIOTICS PRODUCED BY STREPTOMYCES PRODUCING ORGANISM , FERMENTATION , ISOLATION AND BIOLOGICAL ACTIVITIES

H. Nakano, K. Gomi, M. Hara, 2006 .

Induction of mammalian DNA topoisomerase I-mediated DNA cleavage and DNA winding by bulgarein.

H. Nakano, Y. Yamashita, Y. Saitoh, 1993, The Journal of biological chemistry.

Induction of mammalian DNA topoisomerase I mediated DNA cleavage by antitumor indolocarbazole derivatives.

T. Ashizawa, H. Nakano, M. Okabe, 1992, Biochemistry.

6-Deoxyilludin M, a new antitumor antibiotic: fermentation, isolation and structural identification.

H. Nakano, M. Morimoto, M. Hara, 1987, The Journal of antibiotics.

The clecarmycins, new antitumor antibiotics produced by Streptomyces: fermentation, isolation and biological properties.

H. Nakano, M. Hara, E. Kobayashi, 1995, The Journal of antibiotics.

Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis.

H. Hosaka, T. Ikegami, H. Wada, 2006, Proceedings of the National Academy of Sciences of the United States of America.

GTP-binding proteins and adenylate cyclase activity in v-Ki-ras transformed NIH/3T3 fibroblast cells.

Y. Nomura, H. Nakano, M. Noda, 1988, Biochemical and biophysical research communications.

UCS15A, a novel small molecule, SH3 domain-mediated protein–protein interaction blocking drug

Sreenath V. Sharma, H. Nakano, C. Oneyama, 2002, Oncogene.

Synthetic inhibitors of proline-rich ligand-mediated protein-protein interaction: potent analogs of UCS15A.

Sreenath V. Sharma, H. Nakano, C. Oneyama, 2003, Chemistry & biology.

Chemical biology of natural indolocarbazole products: 30 years since the discovery of staurosporine

S. Ōmura, H. Nakano, 2009, The Journal of Antibiotics.

Enzymatic synthesis of N-acetylglucosaminyl-cyclodextrin by the reverse reaction of N-acetylhexosaminidase from jack bean.

H. Nakano, K. Fujita, K. Koizumi, 1999, Bioscience, biotechnology, and biochemistry.

Esterification of glycosides by a mono- and diacylglycerol lipase from Penicillium camembertii and comparison of the products with Candida cylindracea lipase

Y. Shimada, Y. Tominaga, H. Nakano, 1995 .

Saintopin, a dual inhibitor of DNA topoisomerases I and II, as a probe for drug-enzyme interactions.

Y. Pommier, H. Nakano, G. Kohlhagen, 1994, The Journal of biological chemistry.

Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties

K. Matsushima, M. Ohira, H. Nagase, 2020, Nature Communications.

Sugar oxidation profiles of membrane-bound dehydrogenase from Acetobacter orientalis

H. Nakano, Takashi Kimura, T. Kiryu, 2012 .

Lactobionic and cellobionic acid production profiles of the resting cells of acetic acid bacteria

H. Nakano, T. Kiryu, T. Kiso, 2015, Bioscience, biotechnology, and biochemistry.

Fermentative Production of Lactobionic Acid by Burkholderia cepacia

H. Nakano, H. Yoshizumi, S. Kitahata, 2003 .

Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor

S. Ōmura, S. Hirono, H. Nakano, 2013, Proceedings of the National Academy of Sciences.

Short peptide tags increase the yield of C-terminally labeled protein

M. Shirai, H. Nakano, D. Naka, 2007, Biotechnology Letters.

Correlation between the formation of cleavable complex with topoisomerase I and growth-inhibitory activity for saintopin-type antibiotics.

T. Mizukami, H. Nakano, Y. Yamashita, 1997, Molecular pharmacology.

UCE6, a new antitumor antibiotic with topoisomerase I mediated DNA cleavage activity, from actinomycetes.

H. Nakano, Y. Yamashita, Y. Saitoh, 1993, Journal of antibiotics (Tokyo. 1968).

Induction of protein-DNA complexes in HeLa S3 cells by KW-2149, a new derivative of mitomycin C.

H. Nakano, H. Saito, M. Kasai, 1993, Cancer research.

Induction of mammalian DNA topoisomerase II dependent DNA cleavage by antitumor antibiotic streptonigrin.

H. Nakano, Y. Yamashita, S. Kawada, 1990, Cancer research.

Terpentecin and ECT4B, new family of topoisomerase II targeting antitumor antibiotics produced by Streptomyces: producing organism, fermentation and large scale purification.

K. Ochiai, H. Nakano, Y. Yamashita, 1995, The Journal of antibiotics.

UCT4B, a new antitumor antibiotic with topoisomerase II mediated DNA cleavage activity. Structure determination.

H. Nakano, H. Sano, Y. Saitoh, 1993, The Journal of antibiotics.

UCT1072s, new antitumor antibiotics with topoisomerase II mediated DNA cleavage activity, from Aspergillus sp.

T. Ashizawa, T. Mizukami, A. Asai, 1999, The Journal of antibiotics.

UCN-01 and UCN-02, new selective inhibitors of protein kinase C. II. Purification, physico-chemical properties, structural determination and biological activities.

I. Takahashi, T. Tamaoki, H. Nakano, 1989, The Journal of antibiotics.

Tertiary peptide bond containing‐oligo(Leu)s

H. Nakano, K. Ishikawa, M. Narita, 2009 .

Staurosporine inhibits tyrosine-specific protein kinase activity of Rous sarcoma virus transforming protein p60.

H. Iba, Y. Kuzuu, I. Takahashi, 1987, The Journal of antibiotics.

Sertraline, chlorprothixene, and chlorpromazine characteristically interact with the REST-binding site of the corepressor mSin3, showing medulloblastoma cell growth inhibitory activities

Y. Fukunishi, H. Nakano, Y. Nishimura, 2018, Scientific Reports.

Design and synthesis of an in vivo-efficacious PIM3 kinase inhibitor as a candidate anti-pancreatic cancer agent.

N. Mukaida, H. Nakano, T. Nagano, 2015, Bioorganic & medicinal chemistry letters.

Narrow-spectrum inhibitors targeting an alternative menaquinone biosynthetic pathway of Helicobacter pylori.

S. Ōmura, H. Nakano, H. Matsui, 2016, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Inhibition of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase by ß-D-4-O-sulfo-N-acetylgalactosaminides bearing various hydrophobic aglycons

H. Nakano, O. Habuchi, Shiori Ohtake-Niimi, 2010, Glycoconjugate Journal.

Design and Synthesis of Potent and Selective PIM Kinase Inhibitors by Targeting Unique Structure of ATP-Binding Pocket.

H. Nakano, T. Nagano, H. Kojima, 2017, ACS medicinal chemistry letters.

A mimetic of the mSin3-binding helix of NRSF/REST ameliorates abnormal pain behavior in chronic pain models.

H. Kouji, H. Ueda, H. Nakano, 2017, Bioorganic & medicinal chemistry letters.

Hydrolysis of beta-galactosyl ester linkage by beta-galactosidases.

H. Nakano, S. Kitahata, T. Terai, 2000, Bioscience, biotechnology and biochemistry.

Structure dependence of intramolecular electron transfer reactions of simple dyads of a zinc(ii) porphyrin complex bearing a peripheral bipyridine moiety.

H. Nakano, Takeyoshi Yagyu, M. Inamo, 2017, Dalton transactions.

Purification and Some Properties of a Levanase from Streptomyces sp. No. 7–3

H. Nakano, Y. Tamura, K. Mizutani, 1990 .

Purification and Properties of Urease fromBrevibacterium ammoniagenes

H. Nakano, Yasuto Watanabe, S. Takenishi, 1984 .

Transfructosylation of Thiol Group by β-Fructofuranosidases

H. Nakano, S. Kitahata, M. Shizuma, 2000 .

Transfructosylation of thiol group by beta-fructofuranosidases.

H. Nakano, S. Kitahata, M. Shizuma, 2000, Bioscience, biotechnology, and biochemistry.

Purification and Some Properties of a New Levanase from Bacillus sp. No. 71.

H. Nakano, K. Mizutani, S. Kitahata, 1992, Bioscience, biotechnology, and biochemistry.

Enzymatic Synthesis of IV-Acetylglucosaminyl-cyclodextrin by the Reverse Reaction of IV-Acetylhexosaminidase fromJack Bean

H. Nakano, A. Hara, K. Koizumi, 2017 .

Drug-target identification from total cellular lysate by drug-induced conformational changes.

K. Yano, Sreenath V. Sharma, H. Nakano, 2009, Analytical biochemistry.

Inexpensive High-Throughput Screening of Kinase Inhibitors Using One-Step Enzyme-Coupled Fluorescence Assay for ADP Detection

H. Nakano, T. Nagano, H. Kojima, 2018, SLAS discovery : advancing life sciences R & D.

Synthesis of N-Acetylglucosaminyl-Maltosyl-Cyclodextrin by Lysozyme

H. Nakano, K. Fujita, K. Koizumi, 1999 .

Production of structured lipids containing essential fatty acids by immobilizedRhizopus delemar lipase

Y. Shimada, A. Sugihara, Y. Tominaga, 1996 .

Fatty acid specificity of Rhizopus delemar lipase in acidolysis

Y. Shimada, A. Sugihara, Y. Tominaga, 1997 .

Enrichment of arachidonic acid: Selective hydrolysis of a single-cell oil fromMortierella withCandida cylindracea lipase

Y. Shimada, A. Sugihara, Y. Tominaga, 1995 .

Esterification of Glycosides with Glycerol and Trimethylolpropane Moieties by Candida cylidracea Lipase

Y. Tominaga, H. Nakano, S. Kitahata, 1991 .

Chemical synthesis of 4-azido-β-galactosamine derivatives for inhibitors of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase

H. Nakano, K. Hidari, K. Yamana, 2018, Glycoconjugate Journal.

Corynecin (chloramphenicol analogs) fermentation studies: Selective production of Corynecin I by Corynebacterium hydrocarboclastus grown on acetate

H. Nakano, F. Tomita, Takeo Suzuki, 1977, Biotechnology and bioengineering.

Theoretical Analysis of Activity Cliffs among Benzofuranone-Class Pim1 Inhibitors Using the Fragment Molecular Orbital Method with Molecular Mechanics Poisson-Boltzmann Surface Area (FMO+MM-PBSA) Approach

Kaori Fukuzawa, Shigeyuki Yokoyama, Shigenori Tanaka, 2017, J. Chem. Inf. Model..

UCN-1028A, a novel and specific inhibitor of protein kinase C, from Cladosporium.

T. Tamaoki, H. Nakano, K. Ando, 1989, The Journal of antibiotics.

SYNTHESES AND PROPERTIES OF TERTIARY PEPTIDE BOND-CONTAINING POLYPEPTIDES. I. YNTHESES AND PROPERTIES OF OLIGO(L-LEUCINE)S CONTAINING PROLINE R GLYCYL-N-(2,4-DIMETHOXYBENZYL)-L-LEUCINE RESIDUES

H. Nakano, K. Ishikawa, M. Narita, 1984 .

Structure dependence of intramolecular electron transfer reactions of simple dyads of a zinc(ii) porphyrin complex bearing a peripheral bipyridine moiety.

H. Nakano, Takeyoshi Yagyu, M. Inamo, 2017, Dalton transactions.

Rational evolution of a novel type of potent and selective proviral integration site in Moloney murine leukemia virus kinase 1 (PIM1) inhibitor from a screening-hit compound.

S. Yokoyama, H. Nakano, T. Nagano, 2012, Journal of medicinal chemistry.

Binding of ras p21 to bands 4.2 and 6 of human erythrocyte membranes

H. Nakano, Y. Takai, M. Kawata, 1988, FEBS letters.

Constituents of a Fern, Davallia mariesii Moore. IV. Isolation and Structures of a Novel Norcarotane Sesquiterpene Glycoside, a Chromone Glucuronide, and Two Epicatechin Glycosides.

T. Tamaoki, H. Nakano, Y. Tezuka, 1992 .