C. Rinker-Schaeffer

发表

In vitro evaluation of flavopiridol, a novel cell cycle inhibitor, in bladder cancer

W. Stadler, M. Chien, Mary Astumian, 1999, Cancer Chemotherapy and Pharmacology.

Up‐regulation of MKK4, MKK6 and MKK7 during prostate cancer progression: an important role for SAPK signalling in prostatic neoplasia

B. Foster, C. Brendler, D. Huo, 2007, The Journal of pathology.

SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancer.

Kevin P. White, Jing Zhang, Yong Tian, 2014, Cancer cell.

Metastasis Suppressor Proteins: Discovery, Molecular Mechanisms, and Clinical Application

D. Theodorescu, C. Rinker-Schaeffer, D. Welch, 2006, Clinical Cancer Research.

Chromosome 17-mediated dormancy of AT6.1 prostate cancer micrometastases.

W. Stadler, C. Rinker-Schaeffer, H. Kim, 1998, Cancer research.

Mitogen-activated protein kinase kinase 4/stress-activated protein/Erk kinase 1 (MKK4/SEK1), a prostate cancer metastasis suppressor gene encoded by human chromosome 17.

W. Stadler, C. Rinker-Schaeffer, Z. Dubauskas, 1999, Cancer research.

Differential suppression of mammary and prostate cancer metastasis by human chromosomes 17 and 11.

J. Barrett, J. Isaacs, C. Griffin, 1994, Cancer research.

Suppression of metastasis--a new function for known proteins.

C. Rinker-Schaeffer, D. V. Vander Griend, Donald J. Vander Griend, 2004, Journal of the National Cancer Institute.

Using MKK4’s metastasis suppressor function to identify and dissect cancer cell–microenvironment interactions during metastatic colonization

C. Rinker-Schaeffer, Shaheen Khan, A. Drew, 2012, Cancer and Metastasis Reviews.

Defining the biologic role of genes that regulate prostate cancer metastasis

C. Rinker-Schaeffer, D. Welch, M. Sokoloff, 2000, Current opinion in urology.

Tumor-Host Interactions at the Metastatic Site: MKK4, Signal Transduction and the Stress Response

V. Robinson, C. Rinker-Schaeffer, Jonathan C. Berger, 2005 .

Inhibition of prostate cancer metastatic colonization by ∼4.2 Mb of human chromosome 12

E. Jaeger, C. Rinker-Schaeffer, M. Sokoloff, 2004 .

Localization of prostate cancer metastasis‐suppressor activity on human chromosome 17

E. Davis, C. Rinker-Schaeffer, Robert C. Smith, 1997, The Prostate.

Mechanism of action and regulation of protein synthesis initiation factor 4E: effects on mRNA discrimination, cellular growth rate, and oncogenesis.

R. Rhoads, S. Joshi‐Barve, C. Rinker-Schaeffer, 1993, Progress in nucleic acid research and molecular biology.

Decreasing the level of translation initiation factor 4E with antisense rna causes reversal of ras‐mediated transformation and tumorigenesis of cloned rat embryo fibroblasts

A. De Benedetti, R. Rhoads, S. Zimmer, 1993, International journal of cancer.

Metastasis-suppressor genes: a review and perspective on an emerging field.

C. Rinker-Schaeffer, D. Welch, M. Sokoloff, 2000, Journal of the National Cancer Institute.

Development of markers of prostate cancer metastasis

C. Rinker-Schaeffer, M. Sokoloff, Z. Dubauskas, 2000 .

Metastasis suppression: the evolving role of metastasis suppressor genes for regulating cancer cell growth at the secondary site.

V. Robinson, W. Stadler, C. Rinker-Schaeffer, 2003, The Journal of urology.

Differentiation of nonmetastatic and metastatic rodent prostate tumors with high spectral and spatial resolution MRI

C. Rinker-Schaeffer, Xiaobing Fan, M. Zamora, 2001, Magnetic resonance in medicine.

Expression of antisense RNA against initiation factor eIF-4E mRNA in HeLa cells results in lengthened cell division times, diminished translation rates, and reduced levels of both eIF-4E and the p220 component of eIF-4F

A. De Benedetti, R. Rhoads, S. Joshi‐Barve, 1991, Molecular and cellular biology.

Metastasis suppressor genes for prostate cancer

M. Oshimura, J. Barrett, J. Isaacs, 1996, The Prostate. Supplement.

Effects of polyamine analogues on prostatic adenocarcinoma cells in vitro and in vivo

L. Marton, C. Rinker-Schaeffer, M. Dolan, 1998, Cancer Chemotherapy and Pharmacology.

Mitogen-activated Protein Kinase Kinase 4 ( MKK 4 ) Acts as a Metastasis Suppressor Gene in Human Ovarian Carcinoma 1

A. Montag, D. Huo, C. Rinker-Schaeffer, 2002 .

Human chromosome 16 suppresses metastasis but not tumorigenesis in rat prostatic tumor cells.

T. Mashimo, M. Watabe, K. Watabe, 1998, Cancer research.

Award Number: DAMD17-01-1-0700 TITLE: Evaluation of the role of the metastasis-suppressor gene MKK4/SEK1 in transgenic models of prostate cancer

Principal Investigator, C. Rinker-Schaeffer, 2007 .

Identification of a novel metastasis-suppressor region on human chromosome 12.

M. L. Le Beau, Shann-Ching Chen, K. Watabe, 1998, Cancer research.

Development of a high‐efficiency method for gene marking of Dunning prostate cancer cell lines with the enzyme β‐galactosidase

J. Simons, J. Isaacs, C. Rinker-Schaeffer, 1996 .

Stopping cancer before it colonizes

C. Rinker-Schaeffer, J. Hickson, 2006, Nature Medicine.

What defines a useful marker of metastasis in human cancer?

C. Rinker-Schaeffer, D. Welch, 1999, Journal of the National Cancer Institute.

Activated calphostin C cytotoxicity is independent of p53 status and in vivo metastatic potential.

W. Stadler, C. Rinker-Schaeffer, T. Chung, 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.

Molecular biology of breast cancer metastasis: Genetic regulation of human breast carcinoma metastasis

P. Steeg, C. Rinker-Schaeffer, D. Welch, 2000, Breast Cancer Research.

Murine Models of Prostate Cancer

C. Rinker-Schaeffer, E. Kauffman, C. Ng, 2013 .

The Dunning model

M. Sokoloff, C. Rinker-Schaeffer, Hyung Kim, 2000, The Prostate.

Using MKK4’s metastasis suppressor function to identify and dissect cancer cell–microenvironment interactions during metastatic colonization

C. Rinker-Schaeffer, Shaheen Khan, A. Drew, 2012, Cancer and Metastasis Reviews.

Molecular and cellular changes associated with the acquisition of metastatic ability by prostatic cancer cells

A. Partin, W. Isaacs, D. S. Coffey, 1994, The Prostate.

Mitogen-activated protein kinase kinase 4 (MKK4) acts as a metastasis suppressor gene in human ovarian carcinoma.

A. Montag, D. Huo, C. Rinker-Schaeffer, 2002, Cancer research.

Mitogen-activated protein kinase kinase 4 metastasis suppressor gene expression is inversely related to histological pattern in advancing human prostatic cancers.

Ximing J. Yang, M. Rubin, A. Lin, 2001, Cancer research.

Omental macrophages secrete chemokine ligands that promote ovarian cancer colonization of the omentum via CCR1

B. Schaar, E. Rankin, Yue Zhang, 2020, Communications Biology.

Omental macrophages secrete chemokine ligands that promote ovarian cancer colonization of the omentum via CCR1

B. Schaar, E. Rankin, C. Rinker-Schaeffer, 2020, Communications biology.

KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2.

J. Barrett, J. Isaacs, C. Rinker-Schaeffer, 1995, Science.

Localization and physical mapping of the prostate-specific membrane antigen (PSM) gene to human chromosome 11.

J. Isaacs, C. Griffin, C. Rinker-Schaeffer, 1995, Genomics.

New paradigms for the function of JNKK1/MKK4 in controlling growth of disseminated cancer cells.

C. Rinker-Schaeffer, S. Yamada, K. Macleod, 2008, Cancer letters.

Mitogen-Activated Protein Kinase Kinase 4/c-Jun NH2-Terminal Kinase Kinase 1 Protein Expression Is Subject to Translational Regulation in Prostate Cancer Cell Lines

M. Gorospe, V. Robinson, T. Kawai, 2008, Molecular Cancer Research.

Mitogen-Activated Protein Kinase Kinase 4 / c-Jun NH 2-Terminal Kinase Kinase 1 Protein Expression Is Subject to Translational Regulation in Prostate Cancer Cell Lines

M. Gorospe, V. Robinson, T. Kawai, 2008 .

Suppression of metastatic colonization by the context-dependent activation of the c-Jun NH2-terminal kinase kinases JNKK1/MKK4 and MKK7.

A. Lin, W. Stadler, C. Rinker-Schaeffer, 2005, Cancer research.

Metastasis suppressor genes: signal transduction, cross-talk and the potential for modulating the behavior of metastatic cells

W. Stadler, C. Rinker-Schaeffer, Jonathan C. Berger, 2004, Anti-cancer drugs.

MKK4 and metastasis suppression: A marriage of signal transduction and metastasis research

V. Robinson, C. Rinker-Schaeffer, D. V. Vander Griend, 2004, Clinical & Experimental Metastasis.

Building on the foundation of daring hypotheses: Using the MKK4 metastasis suppressor to develop models of dormancy and metastatic colonization

J. Shear, C. Rinker-Schaeffer, D. V. Vander Griend, 2011, FEBS letters.

Increased MKK4 Abundance with Replicative Senescence Is Linked to the Joint Reduction of Multiple MicroRNAs

S. Srikantan, M. Gorospe, Xiaoling Yang, 2009, Science Signaling.

The p38 kinases MKK4 and MKK6 suppress metastatic colonization in human ovarian carcinoma.

D. Huo, A. Lin, C. Rinker-Schaeffer, 2006, Cancer research.

From Prostate to Bone: Key Players in Prostate Cancer Bone Metastasis

C. Rinker-Schaeffer, S. Prasad, Robert Clark, 2011, Cancers.

Workgroup I: Rodent models of prostate cancer

D. Bostwick, M. Lucia, I. Leav, 1998, The Prostate.

FYN is overexpressed in human prostate cancer

Ravi Salgia, Javed Siddiqui, Walter M Stadler, 2009, BJU international.

An Orthotopic Model of Human Osteosarcoma Growth and Spontaneous Pulmonary Metastasis

A. Montag, T. He, C. Rinker-Schaeffer, 2005, Clinical & Experimental Metastasis.

Localization of metastasis suppressor gene(s) for rat prostatic cancer to the long arm of human chromosome 10

M. Oshimura, J. Barrett, J. Isaacs, 1995, Genes, chromosomes & cancer.

Prostate cancer — biology of metastasis and its clinical implications

J. Barrett, J. Isaacs, C. Rinker-Schaeffer, 2004, World Journal of Urology.

c-Jun NH2-terminal kinase activating kinase 1/mitogen-activated protein kinase kinase 4-mediated inhibition of SKOV3ip.1 ovarian cancer metastasis involves growth arrest and p21 up-regulation.

D. Huo, C. Rinker-Schaeffer, S. Yamada, 2008, Cancer research.

Societal interactions in ovarian cancer metastasis: a quorum-sensing hypothesis

B. Bassler, C. Rinker-Schaeffer, Carrie Rinker-Schaeffer, 2008, Clinical & Experimental Metastasis.

Highlights of the Society of Urologic Oncology meeting, June 2, 2001.

C. Brendler, G. Steinberg, C. Rinker-Schaeffer, 2002, The Journal of urology.

Metastasis-suppressor genes in clinical practice: lost in translation?

A. Shoushtari, C. Rinker-Schaeffer, R. Szmulewitz, 2011, Nature Reviews Clinical Oncology.

Using metastasis suppressor proteins to dissect interactions among cancer cells and their microenvironment

C. Rinker-Schaeffer, T. Lotan, Jennifer Taylor, 2008, Cancer and Metastasis Reviews.

Metastasis Suppression in Prostate Cancer

E. Jaeger, C. Rinker-Schaeffer, R. Samant, 2004, Cancer and Metastasis Reviews.

Joint Reduction of Multiple MicroRNAs Increased MKK4 Abundance with Replicative Senescence Is Linked to the

S. Srikantan, Xiaoling Yang, K. Masuda, 2010 .

Disrupting Ovarian Cancer Metastatic Colonization: Insights from Metastasis Suppressor Studies

C. Rinker-Schaeffer, Shaheen Khan, Jennifer Taylor, 2010, Journal of oncology.

TITLE: Societal Interactions in Ovarian Cancer Metastases: A Quorum Sensing Hypothesis

Principal Investigator, C. Rinker-Schaeffer, 2008 .

The p 38 Kinases MKK 4 and MKK 6 Suppress Metastatic Colonization in Human Ovarian Carcinoma

D. Huo, A. Lin, C. Rinker-Schaeffer, 2006 .

Metastasis suppressor genes: From gene identification to protein function and regulation

V. Robinson, C. Rinker-Schaeffer, D. V. Vander Griend, 2005, Cancer biology & therapy.

A New Look at an Old Problem: The Survival and Organ-Specific Growth of Metastases

C. Rinker-Schaeffer, D. V. Vander Griend, Donald J. Vander Griend, 2004, Science's STKE.

Thinking outside the box: using metastasis suppressors as molecular tools.

C. Rinker-Schaeffer, Sophie Thiolloy, 2011, Seminars in cancer biology.

The basic biology of metastasis.

V. Robinson, C. Rinker-Schaeffer, M. Sokoloff, 2004, Cancer treatment and research.

The Role of the Omental Microenvironment in Ovarian Cancer Metastatic Colonization

C. Rinker-Schaeffer, V. Krishnan, Robert Clark, 2010 .

In vitro metastatic colonization of human ovarian cancer cells to the omentum

G. Prins, C. Rinker-Schaeffer, T. Lotan, 2010, Clinical and Experimental Metastasis.

Milky spots promote ovarian cancer metastatic colonization of peritoneal adipose in experimental models.

C. Rinker-Schaeffer, Michael Schoof, V. Krishnan, 2013, The American journal of pathology.

The Role of Motility Proteins and Metastasis‐Suppressor Genes in Prostate Cancer Progression

J. Mohler, C. Rinker-Schaeffer, M. Chekmareva, 1996, Stem cells.

Molecular and cellular markers for metastatic prostate cancer

W. Isaacs, J. Isaacs, C. Rinker-Schaeffer, 1993, Cancer Metastasis Review.

Time-dependent transcriptional profiling links gene expression to mitogen-activated protein kinase kinase 4 (MKK4)-mediated suppression of omental metastatic colonization

Y. Gilad, A. Montag, M. Lingen, 2012, Clinical & Experimental Metastasis.

MKK4 suppresses metastatic colonization by multiple highly metastatic prostate cancer cell lines through a transient impairment in cell cycle progression

C. Rinker-Schaeffer, K. Macleod, T. Lotan, 2012, International journal of cancer.

Prostate cancer metastasis-suppressor genes: a current perspective.

J. Nelson, K. Watabe, W. Stadler, 1998, In vivo.

Adjunctive therapy for men with high risk localized and locally advanced prostate cancer: targeting disseminated tumor cells.

C. Brendler, L. Chung, C. Rinker-Schaeffer, 2004, The Journal of urology.

In vitro evaluation of calphostin C as a novel agent for photodynamic therapy of bladder cancer.

W. Stadler, C. Rinker-Schaeffer, T. Chung, 1999, Urology.

Flexible peritoneal windows for quantitative fluorescence and bioluminescence preclinical imaging.

Chin-Tu Chen, C. Rinker-Schaeffer, J. Souris, 2013, Molecular imaging.

Functional and anatomic imaging of tumor vasculature: high-resolution MR spectroscopic imaging combined with a superparamagnetic contrast agent.

Gregory S Karczmar, Marta Zamora, H. Al-Hallaq, 2002, Academic radiology.

Mapping of metastasis suppressor genes for prostate cancer by microcell-mediated chromosome transfer.

M. Oshimura, J. Barrett, H. Suzuki, 2000, Asian journal of andrology.

Ras transformation of cloned rat embryo fibroblasts results in increased rates of protein synthesis and phosphorylation of eukaryotic initiation factor 4E.

R. Rhoads, S. Zimmer, C. Rinker-Schaeffer, 1992, The Journal of biological chemistry.

SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancer.

K. White, S. Karmakar, S. Eggener, 2014, Cancer cell.

Increased MKK4 Abundance with Replicative Senescence Is Linked to the Joint Reduction of Multiple MicroRNAs

S. Srikantan, M. Gorospe, Xiaoling Yang, 2009, Science Signaling.

c-Jun NH2-terminal kinase activating kinase 1/mitogen-activated protein kinase kinase 4-mediated inhibition of SKOV3ip.1 ovarian cancer metastasis involves growth arrest and p21 up-regulation.

D. Huo, C. Rinker-Schaeffer, S. Yamada, 2008, Cancer research.

A G2/M growth arrest response to low-dose intermittent H2O2 in normal uroepithelial cells.

W. Stadler, M. Chien, C. Rinker-Schaeffer, 2000, International journal of oncology.