Chuan-ju Liu

发表

Cytosolic Phospholipase A2 Is Required for Fexofenadine’s Therapeutic Effects against Inflammatory Bowel Disease in Mice

Xiangli Zhao, Ronghan Liu, Yuehong Chen, 2021, International journal of molecular sciences.

Progranulin Facilitates Conversion and Function of Regulatory T Cells under Inflammatory Conditions

Chuan-ju Liu, Yuying Zhang, F. Wei, 2014, PloS one.

Serum interleukin-6 as a marker of periprosthetic infection following total hip and knee arthroplasty.

Chuan-ju Liu, P. D. Di Cesare, Eric Y. Chang, 2005, The Journal of bone and joint surgery. American volume.

Progranulin promotes bone fracture healing via TNFR pathways in mice with type 2 diabetes mellitus

Xin Li, T. Einhorn, A. Hettinghouse, 2021, Annals of the New York Academy of Sciences.

Molecular regulations and therapeutic targets of Gaucher disease.

Yuehong Chen, A. Hettinghouse, Chuan-ju Liu, 2018, Cytokine & growth factor reviews.

p204 Protein Overcomes the Inhibition of the Differentiation of P19 Murine Embryonal Carcinoma Cells to Beating Cardiac Myocytes by Id Proteins*

P. Lengyel, Chuan-ju Liu, Yan Huang, 2006, Journal of Biological Chemistry.

A silencer element in the cartilage oligomeric matrix protein gene regulates chondrocyte‐specific expression

Chuan-ju Liu, P. D. Di Cesare, L. Prazak, 2004, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Leukemia/Lymphoma-related Factor, a POZ Domain-containing Transcriptional Repressor, Interacts with Histone Deacetylase-1 and Inhibits Cartilage Oligomeric Matrix Protein Gene Expression and Chondrogenesis*

Chuan-ju Liu, N. Tyagi, P. D. Di Cesare, 2004, Journal of Biological Chemistry.

Multifunctional molecule ERp57: From cancer to neurodegenerative diseases

Ronghan Liu, A. Hettinghouse, Chuan-ju Liu, 2018, Pharmacology & therapeutics.

Levels of Expression for BMP-7 and Several BMP Antagonists May Play an Integral Role in a Fracture Nonunion: A Pilot Study

Chuan-ju Liu, K. Egol, M. Fajardo, 2009, Clinical orthopaedics and related research.

Granulin epithelin precursor: a bone morphogenic protein 2‐inducible growth factor that activates Erk1/2 signaling and JunB transcription factor in chondrogenesis

Jian Q. Feng, Chuan-ju Liu, S. Frenkel, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

p204, a p200 family protein, as a multifunctional regulator of cell proliferation and differentiation.

P. Lengyel, Yi Luan, Chuan-ju Liu, 2008, Cytokine & growth factor reviews.

Review: Novel Insights Into Tumor Necrosis Factor Receptor, Death Receptor 3, and Progranulin Pathways in Arthritis and Bone Remodeling

Chuan-ju Liu, E. Wang, L. Thurner, 2016, Arthritis & rheumatology.

Progranulin associates with Rab2 and is involved in autophagosome-lysosome fusion in Gaucher disease

Ying Sun, Xiangli Zhao, A. Hettinghouse, 2021, Journal of Molecular Medicine.

Progranulin associates with Rab2 and is involved in autophagosome-lysosome fusion in Gaucher disease.

Xiangli Zhao, A. Hettinghouse, Chuan-ju Liu, 2021, Journal of molecular medicine.

Cartilage Oligomeric Matrix Protein Inhibits Vascular Smooth Muscle Calcification by Interacting With Bone Morphogenetic Protein-2

Qingbo Xu, W. Kong, Xian Wang, 2011, Circulation research.

The role of progranulin in arthritis

A. Hettinghouse, Chuan-ju Liu, Jianlu Wei, 2016, Annals of the New York Academy of Sciences.

Progranulin: A promising therapeutic target for rheumatoid arthritis

Chuan-ju Liu, 2011, FEBS letters.

Chitinase-3-like Protein 1: A Progranulin Downstream Molecule and Potential Biomarker for Gaucher Disease

R. Saunders-Pullman, Yuehong Chen, Chuan-ju Liu, 2018, EBioMedicine.

Progranulin inhibits expression and release of chemokines CXCL9 and CXCL10 in a TNFR1 dependent manner

Chuan-ju Liu, J. Jian, J. Mundra, 2016, Scientific Reports.

GEP constitutes a negative feedback loop with MyoD and acts as a novel mediator in controlling skeletal muscle differentiation

Jian Q. Feng, Chuan-ju Liu, Q. Tian, 2011, Cellular and Molecular Life Sciences.

PGRN protects against colitis progression in mice in an IL-10 and TNFR2 dependent manner

Chuan-ju Liu, Yuying Zhang, Wei Tang, 2014, Scientific Reports.

Targeting tumor necrosis factor receptors in ankylosing spondylitis

A. Hettinghouse, Chuan-ju Liu, Michal Lata, 2018, Annals of the New York Academy of Sciences.

Progranulin: A conductor of receptors orchestra, a chaperone of lysosomal enzymes and a therapeutic target for multiple diseases.

A. Hettinghouse, Chuan-ju Liu, Yazhou Cui, 2019, Cytokine & growth factor reviews.

Repurposing FDA-approved drugs for SARS-CoV-2 through an ELISA-based screening for the inhibition of RBD/ACE2 interaction

Zhe-Sheng Chen, A. Hettinghouse, Chuan-ju Liu, 2020, Protein & Cell.

Extracellular matrix protein 1, a direct targeting molecule of parathyroid hormone‐related peptide, negatively regulates chondrogenesis and endochondral ossification via associating with progranulin growth factor

Jian Q. Feng, Chuan-ju Liu, J. Merregaert, 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Progranulin Knockout Accelerates Intervertebral Disc Degeneration in Aging Mice

Chuan-ju Liu, Q. Tian, T. Jia, 2015, Scientific Reports.

Progranulin protects against osteoarthritis through interacting with TNF-α and β-Catenin signalling

Chuan-ju Liu, Q. Tian, B. Richbourgh, 2014, Annals of the rheumatic diseases.

Establishment of a surgically-induced model in mice to investigate the protective role of progranulin in osteoarthritis.

Chuan-ju Liu, Yun-peng Zhao, Ben Liu, 2014, Journal of visualized experiments : JoVE.

Fexofenadine inhibits TNF signaling through targeting to cytosolic phospholipase A2 and is therapeutic against autoimmune diseases

Zhe-Sheng Chen, Ronghan Liu, Yuehong Chen, 2019, bioRxiv.

TNFR2/14-3-3ε signaling complex instructs macrophage plasticity in inflammation and autoimmunity.

P. Loke, D. Solit, G. Xiao, 2021, The Journal of clinical investigation.

Progranulin Recruits HSP70 to β-Glucocerebrosidase and Is Therapeutic Against Gaucher Disease

Ying Sun, K. Setchell, A. Hettinghouse, 2016, EBioMedicine.

Progranulin derivative Atsttrin protects against early osteoarthritis in mouse and rat models

O. Kennedy, A. Hettinghouse, Chuan-ju Liu, 2017, Arthritis Research & Therapy.

Does progranulin account for the opposite effects of etanercept and infliximab/adalimumab in osteoarthritis?

Chuan-ju Liu, J. Buza, Jian-lu Wei, 2016, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Progranulin: a Conductor of a Receptors Orchestra and a Therapeutic Target for Multiple Diseases

A. Hettinghouse, Chuan-ju Liu, Yazhou Cui, 2019 .

Chapter 264 – ADAMTS7

Chuan-ju Liu, 2013 .

The role of ADAMTSs in arthritis

Chuan-ju Liu, E. Lin, 2010, Protein & Cell.

The emerging roles of ADAMTS-7 and ADAMTS-12 matrix metalloproteinases

Chuan-ju Liu, E. Lin, 2009, Open access rheumatology : research and reviews.

ADAMTS-7, a Direct Target of PTHrP, Adversely Regulates Endochondral Bone Growth by Associating with and Inactivating GEP Growth Factor

Chuan-ju Liu, H. Kronenberg, Xiu-ping Yu, 2009, Molecular and Cellular Biology.

The role of ADAMTS-7 and ADAMTS-12 in the pathogenesis of arthritis

Chuan-ju Liu, 2009, Nature Clinical Practice Rheumatology.

Progranulin deficiency exaggerates, whereas progranulin‐derived Atsttrin attenuates, severity of dermatitis in mice

Chuan-ju Liu, Q. Tian, Yun-peng Zhao, 2013, FEBS letters.

Progranulin associates with hexosaminidase A and ameliorates GM2 ganglioside accumulation and lysosomal storage in Tay-Sachs disease

Ying Sun, K. Setchell, Yuehong Chen, 2018, Journal of Molecular Medicine.

Progranulin acts as a shared chaperone and regulates multiple lysosomal enzymes

A. Hettinghouse, Chuan-ju Liu, J. Jian, 2017, Genes & diseases.

Overexpression of ADAMTS-7 leads to accelerated initiation and progression of collagen-induced arthritis in mice

Chuan-ju Liu, Yuying Zhang, F. Wei, 2015, Molecular and Cellular Biochemistry.

14-3-3 epsilon is an intracellular component of TNFR2 receptor complex and its activation protects against osteoarthritis

Meng Chen, E. Strauss, Ronghan Liu, 2021, Annals of the Rheumatic Diseases.

Pharmacological and Therapeutic Applications of Esculetin

Chuan-ju Liu, J. Gupta, D. Sahu, 2022, International journal of molecular sciences.

SP0143 Progranulin meets TNF in inflammatory arthritis

Chuan-ju Liu, C. Liu, 2013 .

Interaction between cartilage oligomeric matrix protein and extracellular matrix protein 1 mediates endochondral bone growth.

Chuan-ju Liu, P. D. Di Cesare, J. Merregaert, 2010, Matrix biology : journal of the International Society for Matrix Biology.

Cartilage Oligomeric Matrix Protein Associates with Granulin-Epithelin Precursor (GEP) and Potentiates GEP-stimulated Chondrocyte Proliferation*

Jian Q. Feng, Chuan-ju Liu, P. D. Di Cesare, 2007, Journal of Biological Chemistry.

GEP constitutes a negative feedback loop with MyoD and acts as a novel mediator in controlling skeletal muscle differentiation

Jian Q. Feng, Chuan-ju Liu, Q. Tian, 2012, Cellular and Molecular Life Sciences.

Injectable Progranulin-derivative Atsttrin loaded Protein Engineered Gels for Post Traumatic Osteoarthritis

Rajiv G Menon, R. Regatte, A. Hettinghouse, 2021, bioRxiv.

Novel Peptide Inhibitor of Human Tumor Necrosis Factor-α has Antiarthritic Activity

R. Yennamalli, Chuan-ju Liu, A. Panda, 2022, bioRxiv.

ADAMTS‐7: a metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein

W. Kong, Chuan-ju Liu, P. D. Di Cesare, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Matrix Metalloproteinases That Associate With and Cleave Bone Morphogenetic Protein-2 In Vitro Are Elevated in Hypertrophic Fracture Nonunion Tissue

Chuan-ju Liu, K. Egol, M. Fajardo, 2010, Journal of orthopaedic trauma.

GEP, a Local Growth Factor, is Critical for Odontogenesis and Amelogenesis

Jian Q. Feng, Chuan-ju Liu, Baichun Jiang, 2010, International journal of biological sciences.

Progranulin suppresses titanium particle induced inflammatory osteolysis by targeting TNFα signaling

T. Einhorn, Chuan-ju Liu, Q. Tian, 2016, Scientific Reports.

MicroRNAs in skeletogenesis.

Chuan-ju Liu, 2009, Frontiers in bioscience.

Injectable recombinant block polymer gel for sustained delivery of therapeutic protein in post traumatic osteoarthritis.

R. Regatte, A. Hettinghouse, Chuan-ju Liu, 2022, Biomaterials.

miR-199a*, a Bone Morphogenic Protein 2-responsive MicroRNA, Regulates Chondrogenesis via Direct Targeting to Smad1*

Yi Luan, Chuan-ju Liu, X. Bai, 2009, Journal of Biological Chemistry.

Role of ADAMTS‐12 in Protecting Against Inflammatory Arthritis in Mice By Interacting With and Inactivating Proinflammatory Connective Tissue Growth Factor

A. Hettinghouse, Chuan-ju Liu, K. Lipson, 2018, Arthritis & rheumatology.

ADAMTS-18: a metalloproteinase with multiple functions.

Chuan-ju Liu, Zongdong Li, Jianlu Wei, 2014, Frontiers in bioscience.

p204 protein overcomes the inhibition of core binding factor alpha-1-mediated osteogenic differentiation by Id helix-loop-helix proteins.

Yi Luan, Chuan-ju Liu, N. Yang, 2008, Molecular biology of the cell.

The Retinoblastoma Protein Is an Essential Mediator of Osteogenesis That Links the p204 Protein to the Cbfa1 Transcription Factor Thereby Increasing Its Activity*

P. Lengyel, Yi Luan, Chuan-ju Liu, 2007, Journal of Biological Chemistry.

Progranulin: a growth factor, a novel TNFR ligand and a drug target.

Chuan-ju Liu, X. Bosch, 2012, Pharmacology & therapeutics.

ADAMTS-12 Associates with and Degrades Cartilage Oligomeric Matrix Protein*

Yi Luan, W. Kong, Chuan-ju Liu, 2006, Journal of Biological Chemistry.

MyoD-Dependent Induction during Myoblast Differentiation of p204, a Protein Also Inducible by Interferon

B. Roe, S. Deschamps, P. Lengyel, 2000, Molecular and Cellular Biology.

Foxo4‐ and Stat3‐dependent IL‐10 production by progranulin in regulatory T cells restrains inflammatory arthritis

Michael Loran Dustin, G. Xiao, Chuan-ju Liu, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Progranulin directly binds to the CRD2 and CRD3 of TNFR extracellular domains

Chuan-ju Liu, Q. Tian, J. Jian, 2013, FEBS letters.

The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice

Zhinan Yin, Jian Tao, S. Abramson, 2011, Science.

Progranulin deficiency exacerbates spinal cord injury by promoting neuroinflammation and cell apoptosis in mice

Ronghan Liu, A. Hettinghouse, Chuan-ju Liu, 2019, Journal of Neuroinflammation.

The promotion of bone healing by progranulin, a downstream molecule of BMP-2, through interacting with TNF/TNFR signaling.

Chuan-ju Liu, S. Frenkel, Q. Tian, 2013, Biomaterials.

Fexofenadine inhibits TNF signaling through targeting to cytosolic phospholipase A2 and is therapeutic against inflammatory arthritis

Zhe-Sheng Chen, G. Xiao, Xiangli Zhao, 2019, Annals of the rheumatic diseases.

Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism

J. Weiss, Michael Loran Dustin, Chuan-ju Liu, 2014, Proceedings of the National Academy of Sciences.

p204 Is Required for Canonical Lipopolysaccharide-induced TLR4 Signaling in Mice

G. Xiao, Ronghan Liu, A. Hettinghouse, 2018, EBioMedicine.

IFI16 inhibits tumorigenicity and cell proliferation of bone and cartilage tumor cells.

Chuan-ju Liu, Jin Yu, J. Wittig, 2007, Frontiers in bioscience : a journal and virtual library.

Prevention of Atrophic Nonunion by the Systemic Administration of Parathyroid Hormone (PTH 1–34) in an Experimental Animal Model

Chuan-ju Liu, K. Egol, Alexa Monroy, 2012, Journal of orthopaedic trauma.

The Interferon-inducible p204 Protein Acts as a Transcriptional Coactivator of Cbfa1 and Enhances Osteoblast Differentiation*

P. Lengyel, Chuan-ju Liu, L. Prazak, 2005, Journal of Biological Chemistry.

p204 Is Required for the Differentiation of P19 Murine Embryonal Carcinoma Cells to Beating Cardiac Myocytes

P. Lengyel, Chuan-ju Liu, Yan Huang, 2006, Journal of Biological Chemistry.

The MyoD-Inducible p204 Protein Overcomes the Inhibition of Myoblast Differentiation by Id Proteins

P. Lengyel, Hong Wang, Chuan-ju Liu, 2002, Molecular and Cellular Biology.

Transcriptional activation of cartilage oligomeric matrix protein by Sox9, Sox5, and Sox6 transcription factors and CBP/p300 coactivators.

Chuan-ju Liu, P. D. Di Cesare, Ke Xu, 2007, Frontiers in bioscience : a journal and virtual library.

Clinical Application of Teriparatide in Fracture Prevention: A Systematic Review

Ronghan Liu, Yuehong Chen, A. Hettinghouse, 2019, JBJS reviews.

Cartilage Oligomeric Matrix Protein Maintains the Contractile Phenotype of Vascular Smooth Muscle Cells by Interacting With &agr;7&bgr;1 Integrin

Qingbo Xu, W. Kong, Yuan-sheng Gao, 2010, Circulation research.

PGRN deficiency exacerbates, whereas a brain penetrant PGRN derivative protects, GBA1 mutation-associated pathologies and diseases

Ying Sun, Xiangli Zhao, Chuan-ju Liu, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Association Between Progranulin and Gaucher Disease

Ying Sun, Guilin Wang, R. Saunders-Pullman, 2016, EBioMedicine.

Digoxin targets low density lipoprotein receptor-related protein 4 and protects against osteoarthritis

Zhe-Sheng Chen, A. Hettinghouse, Chuan-ju Liu, 2021, Annals of the Rheumatic Diseases.

Pathogenic mechanisms of glucocorticoid-induced osteoporosis.

Chuan-ju Liu, Huiyun Xu, Meng Chen, 2023, Cytokine & growth factor reviews.

ADAMTS-7 Mediates Vascular Smooth Muscle Cell Migration and Neointima Formation in Balloon-Injured Rat Arteries

Bo Liu, Yi Zhu, Qingbo Xu, 2009, Circulation research.

RbAp48 Is a Critical Mediator Controlling the Transforming Activity of Human Papillomavirus Type 16 in Cervical Cancer*

Chuan-ju Liu, X. Bai, Weiming Zhao, 2007, Journal of Biological Chemistry.

ADAMTS-7 forms a positive feedback loop with TNF-α in the pathogenesis of osteoarthritis

Brendan H. Lee, Yuqing Chen, Chuan-ju Liu, 2013, Annals of the rheumatic diseases.

ADAMTS7 cleavage and vascular smooth muscle cell migration is affected by a coronary-artery-disease-associated variant.

M. Caulfield, Qingbo Xu, S. Kiechl, 2013, American journal of human genetics.

Penfluridol targets acid sphingomyelinase to inhibit TNF signaling and is therapeutic against inflammatory autoimmune diseases

A. Hettinghouse, Chuan-ju Liu, Rongqing Liu, 2022, Arthritis Research & Therapy.

In Vitro Physical and Functional Interaction Assays to Examine the Binding of Progranulin Derivative Atsttrin to TNFR2 and Its Anti-TNFα Activity.

A. Hettinghouse, Chuan-ju Liu, W. Fu, 2020, Methods in molecular biology.

Progranulin promotes diabetic fracture healing in mice with type 1 diabetes

Xin Li, T. Einhorn, Ronghan Liu, 2020, Annals of the New York Academy of Sciences.

Progranulin associates with hexosaminidase A and ameliorates GM2 ganglioside accumulation and lysosomal storage in Tay-Sachs disease

Ying Sun, Yuehong Chen, A. Hettinghouse, 2018, Journal of Molecular Medicine.

Modified yeast-two-hybrid system to identify proteins interacting with the growth factor progranulin.

Chuan-ju Liu, Q. Tian, Yun-peng Zhao, 2012, Journal of visualized experiments : JoVE.

Overexpression of ADAMTS-7 leads to accelerated initiation and progression of collagen-induced arthritis in mice

Chuan-ju Liu, Yuying Zhang, F. Wei, 2015, Molecular and Cellular Biochemistry.

310 IRON OVERLOAD AND HEMOCHROMATOSIS (HFE) MUTATION CORRELATE WITH CLINICAL OUTCOMES IN AN OSTEOARTHRITIS COHORT

S. Abramson, Chuan-ju Liu, M. Attur, 2011 .

Establishment of a Modified Collagen-Induced Arthritis Mouse Model to Investigate the Anti-inflammatory Activity of Progranulin in Inflammatory Arthritis.

Chuan-ju Liu, Jian-lu Wei, 2018, Methods in molecular biology.

Monitoring Atsttrin-Mediated Inhibition of TNFα/NF-κβ Activation Through In Vivo Bioluminescence Imaging.

A. Hettinghouse, Chuan-ju Liu, W. Fu, 2020, Methods in molecular biology.

Progranulin inhibition of TNFα

Chuan-ju Liu, Q. Tian, J. Jian, 2014, Immunology and cell biology.

Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin.

S. Abramson, Chuan-ju Liu, P. D. Di Cesare, 2008, Osteoarthritis and cartilage.

Troxerutin-Mediated Complement Pathway Inhibition is a Disease-Modifying Treatment for Inflammatory Arthritis

A. Rastogi, Chuan-ju Liu, R. Arya, 2022, Frontiers in Cell and Developmental Biology.

Unraveling the mechanisms behind joint damage

Chuan-ju Liu, W. Fu, 2023, eLife.

Chondro-protective effects of low intensity pulsed ultrasound.

David E. Komatsu, A. Hettinghouse, Chuan-ju Liu, 2016, Osteoarthritis and cartilage.

Tau deficiency inhibits classically activated macrophage polarization and protects against collagen-induced arthritis in mice

Chuan-ju Liu, Huiyun Xu, Meng Chen, 2023, Arthritis Research & Therapy.