Ri-zhen Huang

发表

Anti-proliferative effects of diterpenoids from Sagittaria trifolia L. tubers on colon cancer cells by targeting the NF-κB pathway.

Israa Assani, Ying Du, Chungu Wang, 2020, Food & function.

Three new C-27-carboxylated-lupane-triterpenoid derivatives from Potentilla discolor Bunge and their in vitro antitumor activities

Z. Liao, Ri-zhen Huang, Huifeng Chen, 2017, PloS one.

Dual-targeting antitumor hybrids derived from Pt(IV) species and millepachine analogues.

Ri-zhen Huang, S. Gou, Hengshan Wang, 2018, European journal of medicinal chemistry.

Anticancer Platinum(IV) Prodrugs Containing Monoaminophosphonate Ester as a Targeting Group Inhibit Matrix Metalloproteinases and Reverse Multidrug Resistance.

Ri-zhen Huang, S. Gou, Hengshan Wang, 2017, Bioconjugate chemistry.

Combretastatin A-4 Analogue: A Dual-Targeting and Tubulin Inhibitor Containing Antitumor Pt(IV) Moiety with a Unique Mode of Action.

Ri-zhen Huang, S. Gou, Hengshan Wang, 2016, Bioconjugate chemistry.

Pt(IV) complexes conjugating with chalcone analogue as inhibitors of microtubule polymerization exhibited selective inhibition in human cancer cells.

Ri-zhen Huang, S. Gou, Hengshan Wang, 2018, European journal of medicinal chemistry.

Selagintamarlin A: A Selaginellin Analogue Possessing a 1H-2-Benzopyran Core from Selaginella tamariscina

Chungu Wang, Ri-zhen Huang, Bin Zhang, 2017, ACS omega.

Synthesis and biological evaluation of terminal functionalized thiourea-containing dipeptides as antitumor agents

Z. Liao, Ri-zhen Huang, Bin Zhang, 2017 .

Glycyrrhetinic acid derivatives containing aminophosphonate ester species as multidrug resistance reversers that block the NF-κB pathway and cell proliferation.

Ri-zhen Huang, Bin Zhang, Hengshan Wang, 2018, Bioorganic & medicinal chemistry letters.

Synthesis and pharmacological evaluation of dehydroabietic acid thiourea derivatives containing bisphosphonate moiety as an inducer of apoptosis.

Ri-zhen Huang, S. Gou, Yingming Pan, 2016, European journal of medicinal chemistry.

Design, synthesis and antitumor evaluation of new 1,8-naphthalimide derivatives targeting nuclear DNA.

Ri-zhen Huang, Hong Jiang, Hui-Ling Wang, 2020, European journal of medicinal chemistry.

Chemical composition, in vitro anti-tumor activities and related mechanisms of the essential oil from the roots of Potentilla discolor

Z. Liao, Ri-zhen Huang, Jing Zhang, 2018 .

Design, synthesis and pharmacological evaluation of new 2-oxo-quinoline derivatives containing α-aminophosphonates as potential antitumor agents.

Ri-zhen Huang, Zhenfeng Chen, Xian-li Ma, 2017, MedChemComm.

Antitumor lignanamides from the aerial parts of Corydalis saxicola.

Ri-zhen Huang, Hong Liang, Lumei Dai, 2016, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Synthesis and pharmacological evaluation of novel bisindole derivatives bearing oximes moiety: identification of novel proapoptotic agents.

Ri-zhen Huang, Hengshan Wang, Hongen Qu, 2015, European journal of medicinal chemistry.

Pt(IV) prodrugs containing microtubule inhibitors displayed potent antitumor activity and ability to overcome cisplatin resistance.

Ri-zhen Huang, S. Gou, Hengshan Wang, 2018, European journal of medicinal chemistry.

Glechomanamides A-C, Germacrane Sesquiterpenoids with an Unusual Δ8-7,12-Lactam Moiety from Salvia scapiformis and Their Antiangiogenic Activity.

D. Oh, Donghwa Kim, Sang Kook Lee, 2019, Journal of natural products.

Discovery of 18β-glycyrrhetinic acid conjugated aminobenzothiazole derivatives as Hsp90-Cdc37 interaction disruptors that inhibit cell migration and reverse drug resistance.

Ri-zhen Huang, Bin Zhang, Hengshan Wang, 2018, Bioorganic & medicinal chemistry.

Synthesis, antiproliferative and apoptosis-inducing effects of novel asiatic acid derivatives containing α-aminophosphonates

Ri-zhen Huang, Hengshan Wang, Ying-Ming Pan, 2016 .

Cytisine-type alkaloids and flavonoids from the rhizomes of Sophora tonkinensis

Ri-zhen Huang, Hengshan Wang, Ying-Ming Pan, 2016, Journal of Asian natural products research.

[Studies on chemical constituents of rhizomes of Sophora tonkinensis].

Ri-zhen Huang, Hengshan Wang, Ying-Ming Pan, 2016, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

Synthesis and antitumor activities of novel rhein α-aminophosphonates conjugates.

Z. Liao, Ri-zhen Huang, Hengshan Wang, 2014, Bioorganic & medicinal chemistry letters.

Terminal functionalized thiourea-containing dipeptides as multidrug-resistance reversers that target 20S proteasome and cell proliferation.

Ying-Ming Pan, Z. Liao, Ri-zhen Huang, 2017, European journal of medicinal chemistry.

Synthesis and antitumor activity evaluation of maleopimaric acid N-aryl imide atropisomers.

Z. Liao, Ri-zhen Huang, Hengshan Wang, 2013, Bioorganic & medicinal chemistry letters.

Coumarin-containing aminophosphonates bridged with chiral side chain: synthesis and influence of chirality on cytotoxicity and DNA binding

Z. Liao, Ri-zhen Huang, Hengshan Wang, 2013, Medicinal Chemistry Research.

Cyclic pentapeptide type compounds from Clerodendrum japonicum (Thunb.) Sweet

Ri-zhen Huang, Zhenfeng Chen, Hengshan Wang, 2018, Tetrahedron Letters.

Synthesis, mechanisms of action, and toxicity of novel aminophosphonates derivatives conjugated irinotecan in vitro and in vivo as potent antitumor agents.

Ri-zhen Huang, Haijiang Zhang, Hengshan Wang, 2020, European journal of medicinal chemistry.

Synthesis and discovery of asiatic acid based 1,2,3-triazole derivatives as antitumor agents blocking NF-κB activation and cell migration.

Shifeng Zhao, Z. Liao, Ri-zhen Huang, 2019, MedChemComm.

Synthesis and biological evaluation of novel aniline-derived asiatic acid derivatives as potential anticancer agents.

Ri-zhen Huang, Hengshan Wang, Ying-Ming Pan, 2014, European journal of medicinal chemistry.

Synthesis and antitumor properties of novel alizarin analogs

Z. Liao, Ri-zhen Huang, Hengshan Wang, 2014, Medicinal Chemistry Research.

Synthesis and biological evaluation of novel chalcone derivatives as a new class of microtubule destabilizing agents.

Ri-zhen Huang, S. Gou, Hengshan Wang, 2017, European journal of medicinal chemistry.

A pentacyclic triterpene derivative possessing polyhydroxyl ring A suppresses growth of HeLa cells by reactive oxygen species‐dependent NF‐&kgr;B pathway

Ying Du, Chungu Wang, Z. Liao, 2018, European journal of pharmacology.

A new aromatic glycoside and its anti-proliferative activities from the leaves of Bergenia purpurascens

Z. Liao, Ri-zhen Huang, Chengcheng Gong, 2018, Natural product research.

Chemical Constituents of Tibetan Herbal Medicine Pulicaria insignis and Their in vitro Cytotoxic Activities

Peilei Hou, Shifeng Zhao, Yan Feng, 2020 .

Side chain-functionalized aniline-derived ursolic acid derivatives as multidrug resistance reversers that block the nuclear factor-kappa B (NF-κB) pathway and cell proliferation.

Z. Liao, Ri-zhen Huang, Hengshan Wang, 2017, MedChemComm.

Discovery of antitumor ursolic acid long-chain diamine derivatives as potent inhibitors of NF-κB.

Z. Liao, Ri-zhen Huang, Jing Zhang, 2018, Bioorganic chemistry.

Synthesis and molecular docking study of novel alizarin derivatives containing phosphoryl amino acid moiety as potential antitumor agents

Z. Liao, Ri-zhen Huang, Heng-shan Wang, 2017, Medicinal Chemistry Research.

Synthesis and antitumor properties of novel alizarin analogs

Z. Liao, Ri-zhen Huang, Hengshan Wang, 2014, Medicinal Chemistry Research.

Design, synthesis and pharmacological evaluation of novel 2-chloro-3-(1H-benzo[d]imidazol-2-yl)quinoline derivatives as antitumor agents: in vitro and in vivo antitumor activity, cell cycle arrest and apoptotic response

Ri-zhen Huang, Xian-li Ma, Ye Zhang, 2018, RSC advances.

(±)-Corysaxicolaine A: a pair of antitumor enantiomeric alkaloid dimers from Corydalis saxicola.

Ri-zhen Huang, Hengshan Wang, Dong Liang, 2022, Organic & biomolecular chemistry.

16-O-caffeoyl-16-hydroxylhexadecanoic acid, a medicinal plant-derived phenylpropanoid, induces apoptosis in human hepatocarcinoma cells through ROS-dependent endoplasmic reticulum stress.

Z. Liao, Ri-zhen Huang, Bin Zhang, 2018, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Discovery of 2H-chromone-4-one based sulfonamide derivatives as potent retinoic acid receptor-related orphan receptor γt inverse agonists.

Israa Assani, Lei Chen, Shifeng Zhao, 2021, European journal of medicinal chemistry.

Design, synthesis and pharmacological evaluation of new 3-(1H-benzimidazol-2-yl)quinolin-2(1H)-one derivatives as potential antitumor agents.

Ri-zhen Huang, Qi-Pin Qin, Jiao-Lan Qin, 2018, European journal of medicinal chemistry.

Bifunctional Naphthoquinone Aromatic Amide-Oxime Derivatives Exert Combined Immunotherapeutic and Antitumor Effects through Simultaneous Targeting of Indoleamine-2,3-dioxygenase and Signal Transducer and Activator of Transcription 3.

Z. Liao, Ri-zhen Huang, Zhenfeng Chen, 2020, Journal of medicinal chemistry.

Anti-proliferative Activities of Two Flavonols with Unsubstituted B-ring from the Leaves of Platanus acerifolia

Z. Liao, Ri-zhen Huang, Huifeng Chen, 2017 .

Design, synthesis and in vitro evaluation of novel ursolic acid derivatives as potential anticancer agents.

Ri-zhen Huang, Hengshan Wang, Ying-Ming Pan, 2015, European journal of medicinal chemistry.

NF-κB inhibitory and cytotoxic activities of hexacyclic triterpene acid constituents from Glechoma longituba.

Chungu Wang, Z. Liao, Ri-zhen Huang, 2019, Phytomedicine : international journal of phytotherapy and phytopharmacology.

4-Methylumbelliferones Analogues as Anticancer Agents: Synthesis and in Cell Pharmacological Studies.

Ri-zhen Huang, Zhanling Ding, Hengshan Wang, 2017, Anti-cancer agents in medicinal chemistry.

Discovery of dehydroabietic acid sulfonamide based derivatives as selective matrix metalloproteinases inactivators that inhibit cell migration and proliferation.

Z. Liao, Ri-zhen Huang, Bin Zhang, 2017, European journal of medicinal chemistry.

Three new triterpenoid saponins from the aerial parts of Lysimachia foenum-graecum

Ri-zhen Huang, Bin Zhang, Hengshan Wang, 2017 .

Cytotoxic triterpenoid saponins from Lysimachia foenum-graecum.

Ri-zhen Huang, Bin Zhang, Hengshan Wang, 2017, Phytochemistry.

Novel Indole-Chalcone Derivative-Ligated Platinum(IV) Prodrugs Attenuate Cisplatin Resistance in Lung Cancer through ROS/ER Stress and Mitochondrial Dysfunction.

Ri-zhen Huang, Zhikun Liu, Xiao-chao Huang, 2023, Journal of medicinal chemistry.

Platinum(IV) complexes conjugated with phenstatin analogue as inhibitors of microtubule polymerization and reverser of multidrug resistance.

Ri-zhen Huang, S. Gou, Hengshan Wang, 2017, Bioorganic & medicinal chemistry.

Synthesis and molecular docking study of novel alizarin derivatives containing phosphoryl amino acid moiety as potential antitumor agents

Z. Liao, Ri-zhen Huang, Hengshan Wang, 2017, Medicinal Chemistry Research.

Discovery of novel sulfonamide chromone-oxime derivatives as potent indoleamine 2,3-dioxygenase 1 inhibitors.

Ri-zhen Huang, Xian-li Ma, Qi Wang, 2023, European journal of medicinal chemistry.

Discovery of two biotin-PEG4‑diarylidenyl piperidone prodrugs as potent antitumor agents with good efficacy, limited toxicity, and low resistance.

Ri-zhen Huang, Zhijuan Mao, Hui-Ling Wang, 2022, Bioorganic chemistry.

New inhibitors of matrix metalloproteinases 9 (MMP-9): Lignans from Selaginella moellendorffii.

Chungu Wang, Ri-zhen Huang, Hengshan Wang, 2018, Fitoterapia.

Terminal functionalized thiourea-containing dipeptides as multidrug-resistance reversers that target 20S proteasome and cell proliferation.

Z. Liao, Ri-zhen Huang, Hengshan Wang, 2017, European journal of medicinal chemistry.

Synthesis and discovery of asiatic acid based 1,2,3-triazole derivatives as antitumor agents blocking NF-κB activation and cell migration.

Shifeng Zhao, Z. Liao, Ri-zhen Huang, 2019, MedChemComm.

Targeted isolation, structural characterization and cytotoxicity evaluation of isoquinoline alkaloids from Corydalis saxicola

Ri-zhen Huang, Hengshan Wang, Jinjin Zhu, 2023, Journal of Molecular Structure.