Shao-Cong Sun

发表

Genetic evidence for the essential role of beta-transducin repeat-containing protein in the inducible processing of NF-kappa B2/p100.

A. Fong, Shao-Cong Sun, 2002, The Journal of biological chemistry.

NF-kappaB1/p105 regulates lipopolysaccharide-stimulated MAP kinase signaling by governing the stability and function of the Tpl2 kinase.

Shao-Cong Sun, M. Waterfield, Minying Zhang, 2003, Molecular cell.

Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation.

G. Xiao, A. Fong, Shao-Cong Sun, 2004, The Journal of biological chemistry.

beta-TrCP binding and processing of NF-kappaB2/p100 involve its phosphorylation at serines 866 and 870.

Shao-Cong Sun, Minying Zhang, Chunyang Liang, 2006, Cellular signalling.

Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells.

A. Maitra, S. Leach, Kyle Chang, 2018, Gastroenterology.

NF-κB signaling in inflammation

Shao-Cong Sun, Ting Liu, Lingyun Zhang, 2017, Signal Transduction and Targeted Therapy.

Potentiating the antitumour response of CD8+ T cells by modulating cholesterol metabolism

Wei Yang, Shao-Cong Sun, Chenqi Xu, 2016, Nature.

Activation of NF-κB/Rel by Tax involves degradation of IκBα and is blocked by a proteasome inhibitor

E. Harhaj, Shao-Cong Sun, S. Maggirwar, 1995 .

A20 restricts inflammation via ubiquitin binding

Shao-Cong Sun, 2020, Nature Immunology.

Otud7b controls noncanonical NF-κB activation via deubiquitination of TRAF3

Hongbo Hu, Jae-Hoon Chang, George C. Brittain, 2013, Nature.

Immune dysregulation in SHARPIN-deficient mice is dependent on CYLD-mediated cell death

J. Sundberg, S. Lira, Shao-Cong Sun, 2020, bioRxiv.

PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP

Junying Yuan, Shao-Cong Sun, Ying Li, 2017, Proceedings of the National Academy of Sciences.

Receptors and Adaptors for NF-κB Signaling

E. Harhaj, Shao-Cong Sun, 2006 .

Ubiquitin-Specific Protease 25 Regulates TLR4-Dependent Innate Immune Responses Through Deubiquitination of the Adaptor Protein TRAF3

Shao-Cong Sun, C. Dong, Xin Lin, 2013, Science Signaling.

The Brain Proteome of the Ubiquitin Ligase Peli1 Knock-Out Mouse during Experimental Autoimmune Encephalomyelitis

Eystein Oveland, Frode S Berven, Ragnhild Reehorst Lereim, 2016, Journal of proteomics & bioinformatics.

Regulation of IκB Kinase-related Kinases and Antiviral Responses by Tumor Suppressor CYLD*

Shao-Cong Sun, Minying Zhang, W. Jin, 2008, Journal of Biological Chemistry.

Negative Regulation of JNK Signaling by the Tumor Suppressor CYLD*

Shao-Cong Sun, Minying Zhang, W. Reiley, 2004, Journal of Biological Chemistry.

Preventing abnormal NF-κB activation and autoimmunity by Otub1-mediated p100 stabilization

J. Qin, Shao-Cong Sun, Antrix Jain, 2019, Cell Research.

New insight into the oncogenic mechanism of the retroviral oncoprotein Tax

Shao-Cong Sun, Hua Cheng, Tongwei Ren, 2012, Protein & Cell.

Regulation of hematopoiesis by the K63-specific ubiquitin-conjugating enzyme Ubc13

S. Akira, Masahiro Yamamoto, Shao-Cong Sun, 2009, Proceedings of the National Academy of Sciences.

ZRANB1 Is an EZH2 Deubiquitinase and a Potential Therapeutic Target in Breast Cancer.

Li Ma, M. Hung, A. Sood, 2018, Cell reports.

Calpain Contributes to Silica-Induced IκB-α Degradation and Nuclear Factor-κB Activation

Fei Chen, Xianglin Shi, Xianglin Shi, 1997 .

Somatic mutagenesis studies of NF-κB signaling in human T cells: evidence for an essential role of IKKγ in NF-κB activation by T-cell costimulatory signals and HTLV-I Tax protein

E. Harhaj, G. Xiao, Shao-Cong Sun, 2000, Oncogene.

p 50 by a Putative Nuclear Export Signal and Regulation of RelA Subcellular Localization

E. Harhaj, Shao-Cong Sun, 1999 .

Regulation of RelA Subcellular Localization by a Putative Nuclear Export Signal and p50

E. Harhaj, Shao-Cong Sun, 1999, Molecular and Cellular Biology.

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production

Shao-Cong Sun, W. Jin, Mikyoung Chang, 2009, Nature Immunology.

Bypassing STAT3-mediated inhibition of the transcriptional regulator ID2 improves the antitumor efficacy of dendritic cells

C. Liu, P. Hwu, J. Hu, 2016, Science Signaling.

Controlling the Fate of NIK: A Central Stage in Noncanonical NF-κB Signaling

Shao-Cong Sun, 2010, Science Signaling.

Regulation of T-cell activation and migration by the kinase TBK1 during neuroinflammation

Jae-Hoon Chang, Shao-Cong Sun, W. Cao, 2015, Nature Communications.

Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD.

Shao-Cong Sun, Minying Zhang, W. Jin, 2007, Developmental cell.

Deubiquitinating Enzyme CYLD Regulates the Peripheral Development and Naive Phenotype Maintenance of B Cells*♦

Shao-Cong Sun, Minying Zhang, W. Jin, 2007, Journal of Biological Chemistry.

Regulation of T cell development by the deubiquitinating enzyme CYLD

Shao-Cong Sun, Minying Zhang, W. Jin, 2006, Nature Immunology.

Regulation of the Deubiquitinating Enzyme CYLD by IκB Kinase Gamma-Dependent Phosphorylation

Shao-Cong Sun, Minying Zhang, Xuefeng Wu, 2005, Molecular and Cellular Biology.

USP15 suppresses tumor immunity via deubiquitylation and inactivation of TET2

Matthew D. Smith, Y. Xiong, N. G. Brown, 2020, Science Advances.

Targeting ubiquitination for cancer therapies.

J. Morrow, Shuxing Zhang, Hui-Kuan Lin, 2015, Future medicinal chemistry.

Epigenetic regulation of Il12 and Il23 gene expression and autoimmune inflammation by the deubiquitinase Trabid

Hongbo Hu, Shao-Cong Sun, Qiang Zou, 2015, Nature Immunology.

TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival

Shao-Cong Sun, Xiaofei Zhou, Lingyun Zhang, 2018, Nature Communications.

Phosphorylation of NF-kappaB1/p105 by oncoprotein kinase Tpl2: implications for a novel mechanism of Tpl2 regulation.

Shao-Cong Sun, M. Waterfield, Minying Zhang, 2006, Biochimica et biophysica acta.

Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus

B. Li, J. Xu, Shao-Cong Sun, 2018, Nature Communications.

FKBP51 employs both scaffold and isomerase functions to promote NF-κB activation in melanoma

M. Masullo, Shao-Cong Sun, S. Romano, 2015, Nucleic acids research.

Cell intrinsic role of NF-κB-inducing kinase in regulating T cell-mediated immune and autoimmune responses

Lawren C. Wu, Hongbo Hu, Shao-Cong Sun, 2016, Scientific Reports.

TBK 1 controls IgA class switching by negatively regulating noncanonical NF-κ B signaling

Hongbo Hu, Jae-Hoon Chang, Shao-Cong Sun, 2016 .

NF-κB in inflammation and renal diseases

Shao-Cong Sun, Haisong Zhang, Shaocong Sun, 2015, Cell & Bioscience.

T Cell–Intrinsic Function of the Noncanonical NF-κB Pathway in the Regulation of GM-CSF Expression and Experimental Autoimmune Encephalomyelitis Pathogenesis

Shao-Cong Sun, W. Jin, Xuhong Cheng, 2014, The Journal of Immunology.

Immune receptor signaling: from ubiquitination to NF-κB activation

Shao-Cong Sun, 2012, Cellular and Molecular Immunology.

TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling

Hongbo Hu, Jae-Hoon Chang, George C. Brittain, 2012, Nature Immunology.

Peli 1 negatively regulates T-cell activation and prevents autoimmunity

P. Hwu, Jae-Hoon Chang, George C. Brittain, 2011 .

TRAF2 regulates T cell immunity by maintaining a Tpl2-ERK survival signaling axis in effector and memory CD8 T cells

Jae-Hoon Chang, Shao-Cong Sun, Xuhong Cheng, 2020, Cellular & Molecular Immunology.

CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation

Shao-Cong Sun, Shao-Cong Sun, J. Ran, 2014, Proceedings of the National Academy of Sciences.

Human T-Cell Leukemia Virus Type I Tax Activation of NF-KB/Rel Involves Phosphorylation and Degradation of IKBot and RelA (p65)-Mediated Induction of the c-rel Gene

W. Greene, Shao-Cong Sun, C. Beraud, 2022 .

NF-κB Transcription Factors Are Involved in Normal Erythropoiesis

Shao-Cong Sun, Min Zhang, B. Miller, 1998 .

STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13

J. McMurray, P. Mandal, Hongbo Hu, 2014 .

STAT3 restrains RANK- and TLR4-mediated signaling by suppressing expression of the E2 ubiquitin ligase Ubc13

J. McMurray, P. Mandal, Hongbo Hu, 2014, Nature Communications.

CARMA1 Regulation of Regulatory T Cell Development Involves Modulation of Interleukin-2 Receptor Signaling*

Shao-Cong Sun, Hanyin Cheng, Xiaofei Zhou, 2010, The Journal of Biological Chemistry.

NF-κB1 p105 Regulates T Cell Homeostasis and Prevents Chronic Inflammation1

L. Fitzpatrick, Shao-Cong Sun, Minying Zhang, 2009, The Journal of Immunology.

Human T cell leukemia virus type I Tax activates CD40 gene expression via the NF-kappa B pathway.

E. Harhaj, Shao-Cong Sun, B. Wigdahl, 2005, Virology.

NF-κB inducing kinase maintains T cell metabolic fitness in antitumor immunity

Jie Yang, Jing Wang, Shao-Cong Sun, 2020, Nature Immunology.

The deubiquitinase Otub1 controls the activation of CD8 T cells and NK cells by regulating IL-15-mediated priming

Jing Wang, Shao-Cong Sun, G. Manyam, 2019, Nature Immunology.

FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells

Wei Yang, Lai Wei, Shao-Cong Sun, 2018, Nature.

NF-κB-inducing Kinase and IκB Kinase Participate in Human T-cell Leukemia Virus I Tax-mediated NF-κB Activation*

E. Zandi, M. Karin, E. Harhaj, 1998, The Journal of Biological Chemistry.

IKKγ Serves as a Docking Subunit of the IκB Kinase (IKK) and Mediates Interaction of IKK with the Human T-cell Leukemia Virus Tax Protein*

E. Harhaj, Shao-Cong Sun, 1999, The Journal of Biological Chemistry.

TRIM28 mediates chromatin modifications at the TCRα enhancer and regulates the development of T and natural killer T cells

Shao-Cong Sun, Minying Zhang, Dapeng Zhou, 2012, Proceedings of the National Academy of Sciences.

KAP1 Regulates Regulatory T Cell Function and Proliferation in Both Foxp3-Dependent and -Independent Manners

S. Ziegler, Shigeru Tanaka, Shao-Cong Sun, 2018, Cell reports.

IKB / MAD-3 Masks the Nuclear Localization Signal of NF-KB p 65 and Requires the Transactivation Domain to Inhibit NF-KB p 65 DNA Binding

W. Greene, A. Parham, Shao-Cong Sun, 2022 .

Cell type-specific function of TRAF2 and TRAF3 in regulating type I IFN induction

Shao-Cong Sun, Baoyu Zhao, Pingwei Li, 2019, Cell & Bioscience.

Peli1 Modulates the Subcellular Localization and Activity of Mdmx.

W. Gu, Dawei Li, O. Tavana, 2018, Cancer research.

IKB/MAD-3 MaskstheNuclear Localization Signal of NF-KBp65andRequires theTransactivation Domain toInhibit NF-KBp65DNA Binding

Shao-Cong Sun, 1992 .

Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice.

Shao-Cong Sun, Minying Zhang, W. Jin, 2008, The Journal of clinical investigation.

An Atypical Tumor Necrosis Factor (TNF) Receptor-associated Factor-binding Motif of B Cell-activating Factor Belonging to the TNF Family (BAFF) Receptor Mediates Induction of the Noncanonical NF-κB Signaling Pathway*

Shao-Cong Sun, Minying Zhang, W. Reiley, 2005, Journal of Biological Chemistry.

Kinase Is an Essential Component of the Tpl 2 Signaling Pathway

Shao-Cong Sun, M. Waterfield, Minying Zhang, 2004 .

This information is current as Ligase Cbl Signaling by Inhibiting the E 3 Ubiquitin Plasmacytoid Dendritic Cell Receptor CD 2 AP / SHIP 1 Complex Positively Regulates

Yong‐jun Liu, Shao-Cong Sun, W. Cao, 2012 .

Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination.

Shao-Cong Sun, Ting Liu, Lingyun Zhang, 2021, Cell reports.

Interferon Response Elements by NF-{ kappa } B p 50 The Specificity of Innate Immune Responses Is Enforced by Repression of

A. Hoffmann, J. Ponomarenko, C. Benedict, 2011 .

Activation of the Transcription Factor c-Maf in T Cells Is Dependent on the CARMA1-IKKβ Signaling Cascade

R. Nurieva, P. Chiao, Shao-Cong Sun, 2013, Science Signaling.

TPL2 mediates IL-17R signaling in neuroinflammation

Shao-Cong Sun, Yichuan Xiao, 2015, Oncotarget.

Distinct Signal Codes Generate Dendritic Cell Functional Plasticity

Shao-Cong Sun, S. Hanabuchi, N. Watanabe, 2010, Science Signaling.

The Serine/Threonine Phosphatase Inhibitor Calyculin A Induces Rapid Degradation of IκBβ

E. Harhaj, Shao-Cong Sun, 1997, The Journal of Biological Chemistry.

Human T-Cell Leukemia Virus Type I Tax Associates with and Is Negatively Regulated by the NF-iB2 plOO Gene Product: Implications for Viral Latency

Shao-Cong Sun, D. Ballard, P. Ganchi, 2022 .

Deregulated Activation of Oncoprotein Kinase Tpl2/Cot in HTLV-I-transformed T Cells*

Shao-Cong Sun, M. Waterfield, Xuefeng Wu, 2006, Journal of Biological Chemistry.

Regulation of the Deubiquitinating Enzyme CYLD by I (cid:2) B Kinase Gamma-Dependent Phosphorylation†

Shao-Cong Sun, Minying Zhang, Xuefeng Wu, 2005 .

A special issue on NF-κB signaling and function

Shao-Cong Sun, Zheng-Gang Liu, 2011, Cell Research.

S9, a 19 S Proteasome Subunit Interacting with Ubiquitinated NF-κB2/p100*

A. Fong, Shao-Cong Sun, Minying Zhang, 2002, The Journal of Biological Chemistry.

Microglia promote autoimmune inflammation via the noncanonical NF-κB pathway

Shao-Cong Sun, Xuhong Cheng, Yanchuan Li, 2021, Science advances.

Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination

Hongbo Hu, Jae-Hoon Chang, Shao-Cong Sun, 2016, The Journal of experimental medicine.

Otud 7 b facilitates T cell activation and inflammatory responses by regulating Zap 70 ubiquitination

Hongbo Hu, Jae-Hoon Chang, Shao-Cong Sun, 2016 .

Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation.

Jae-Hoon Chang, Shao-Cong Sun, Xin Lin, 2014, Immunity.

Negative Regulation of the Nuclear Factor κB-inducing Kinase by a cis-Acting Domain*

G. Xiao, Shao-Cong Sun, 2000, The Journal of Biological Chemistry.

NF-κB Signaling Pathway Governs TRAIL Gene Expression and Human T-cell Leukemia Virus-I Tax-induced T-cell Death*

G. Xiao, A. Fong, Shao-Cong Sun, 2001, The Journal of Biological Chemistry.

Tetrandrine Inhibits Signal-Induced NF-κB Activation in Rat Alveolar Macrophages

Xianglin Shi, Fei Chen, Shao-Cong Sun, 1997 .

Regulation of antiviral innate immunity by deubiquitinase CYLD

Shao-Cong Sun, Minying Zhang, Xuefeng Wu, 2011, Cellular and Molecular Immunology.

The E3 ubiquitin ligase GRAIL regulates T cell tolerance and regulatory T cell function by mediating T cell receptor-CD3 degradation.

R. Nurieva, G. Lozano, Shao-Cong Sun, 2010, Immunity.

Lymphatic endothelial cells regulate B-cell homing to lymph nodes via a NIK-dependent mechanism

Shao-Cong Sun, Lingyun Zhang, Xuhong Cheng, 2019, Cellular & Molecular Immunology.

TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling

J. Harper, Jinfang Zhang, Wenyi Wei, 2017, Nature.

Meet Our Editorial Board Member

Shao-Cong Sun, 2019, Current Immunology Reviews.

TSLP production by epithelial cells exposed to immunodeficiency virus triggers DC-mediated mucosal infection of CD4+ T cells

Christopher J. Miller, S. Ziegler, Shao-Cong Sun, 2009, Proceedings of the National Academy of Sciences.

New insights into NF- κ B regulation and function

S. Ley, Shao-Cong Sun, 2018 .

Activation of IKKα and IKKβ through their fusion with HTLV-I Tax protein

G. Xiao, Shao-Cong Sun, 2000, Oncogene.

Non-canonical NF-κB signaling pathway

Shao-Cong Sun, Shao-Cong Sun, 2011, Cell Research.

Regulation of NF-kappaB2/p100 processing by its nuclear shuttling.

Shao-Cong Sun, G. Liao, 2003, Oncogene.

S9, a 19 S proteasome subunit interacting with ubiquitinated NF-kappaB2/p100.

A. Fong, Shao-Cong Sun, Minying Zhang, 2002, The Journal of biological chemistry.

Triad3a induces the degradation of early necrosome to limit RipK1-dependent cytokine production and necroptosis

E. Alnemri, R. Korneluk, S. Sad, 2018, Cell Death & Disease.

SUPPLEMENTAL INFORMATION c-Cbl regulates dendritic cell activation

Payam Shahi, J. Levitt, Hongbo Hu, 2011 .

Crosstalk between STAT3 and RANK signaling pathways during osteoclastogenesis (174.7)

Hongbo Hu, Shao-Cong Sun, S. Watowich, 2012, The Journal of Immunology.

Deregulation of NF-kappaB and its upstream kinases in cancer.

G. Xiao, Shao-Cong Sun, 2003, Cancer metastasis reviews.

The Specificity of Innate Immune Responses Is Enforced by Repression of Interferon Response Elements by NF-κB p50

A. Hoffmann, J. Ponomarenko, C. Benedict, 2011, Science Signaling.

Persistent activation of NF-κB by the Tax transforming protein of HTLV-1: hijacking cellular IκB kinases

Shao-Cong Sun, D. Ballard, 1999, Oncogene.

Regulation of Th17 cell differentiation and EAE induction by MAP3K NIK.

Shao-Cong Sun, W. Jin, Xuhong Cheng, 2009, Blood.

Regulation of Th 17 cell differentiation and EAE induction by MAP 3 K NIK *

Shao-Cong Sun, W. Jin, Xuhong Cheng, 2009 .

Ubiquitin signaling in immune responses

Hongbo Hu, Shao-Cong Sun, Hongbo Hu, 2016, Cell Research.

The non-canonical NF-κB pathway in immunity and inflammation

Shao-Cong Sun, Shao-Cong Sun, 2017, Nature Reviews Immunology.

Regulation of nuclear factor-κB in autoimmunity.

Jae-Hoon Chang, Shao-Cong Sun, Jin Jin, 2013, Trends in immunology.

TCR signaling to NF-κB and mTORC1: Expanding roles of the CARMA1 complex.

Shao-Cong Sun, Jian-Hong Shi, 2015, Molecular immunology.

NF-κB in inflammation and renal diseases

Shao-Cong Sun, Haisong Zhang, 2015, Cell & Bioscience.

Targeting ubiquitin signaling for cancer immunotherapy

Shao-Cong Sun, Xiaofei Zhou, 2021, Signal Transduction and Targeted Therapy.

The E3 ligase c‐Cbl regulates dendritic cell activation

Payam Shahi, J. Levitt, Hongbo Hu, 2011, EMBO reports.

Noncanonical NF-κB pathway controls the production of type I interferons in antiviral innate immunity.

Frédérick A. Mallette, Hongbo Hu, George C. Brittain, 2014, Immunity.

NF-κB as a target for oncogenic viruses.

E. Cesarman, Shao-Cong Sun, 2011, Current topics in microbiology and immunology.

Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses

L. Fitzpatrick, Shao-Cong Sun, Minying Zhang, 2007, The Journal of experimental medicine.

Deubiquitylation and regulation of the immune response

Shao-Cong Sun, 2008, Nature Reviews Immunology.

Deubiquitinases as pivotal regulators of T cell functions

Shao-Cong Sun, Xiao-Dong Yang, 2018, Frontiers of Medicine.

Regulation of the NF-κB-inducing Kinase by Tumor Necrosis Factor Receptor-associated Factor 3-induced Degradation*

E. Harhaj, Shao-Cong Sun, Minying Zhang, 2004, Journal of Biological Chemistry.

The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia.

A. Statnikov, K. Rajewsky, O. Abdel-Wahab, 2010, Cancer cell.

NF-κB-Inducing Kinase Regulates the Processing of NF-κB2 p100

E. Harhaj, G. Xiao, Shao-Cong Sun, 2001 .

Activation by IKKα of a Second, Evolutionary Conserved, NF-κB Signaling Pathway

Michael Karin, M. Karin, G. Bonizzi, 2001, Science.

USP15 stabilizes MDM2 to mediate cancer cell survival and inhibit antitumor T cell responses

Peirong Yang, G. Lozano, Hongbo Hu, 2014, Nature Immunology.

TPL2 mediates autoimmune inflammation through activation of the TAK1 axis of IL-17 signaling

Hongbo Hu, George C. Brittain, Shao-Cong Sun, 2014, The Journal of experimental medicine.

Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation

Xiaodong Wang, Hongbo Hu, Jae-Hoon Chang, 2013, Nature Medicine.

Gene expression profiles in HTLV-I-immortalized T cells: deregulated expression of genes involved in apoptosis regulation

E. Harhaj, G. Xiao, Shao-Cong Sun, 1999, Oncogene.

Involvement of NF-AT in Type I Human T-cell Leukemia Virus Tax-mediated Fas Ligand Promoter Transactivation*

E. Harhaj, S. Sun, Shao-Cong Sun, 1998, The Journal of Biological Chemistry.

Activation of NF-κB by HTLV-I and implications for cell transformation

S. Yamaoka, Shao-Cong Sun, 2005, Oncogene.

Induction of p100 Processing by NF-κB-inducing Kinase Involves Docking IκB Kinase α (IKKα) to p100 and IKKα-mediated Phosphorylation*

G. Xiao, A. Fong, Shao-Cong Sun, 2004, Journal of Biological Chemistry.

Retroviral oncoprotein Tax induces processing of NF‐κB2/p100 in T cells: evidence for the involvement of IKKα

E. Harhaj, G. Xiao, A. Fong, 2001 .

IκB Kinase Is an Essential Component of the Tpl2 Signaling Pathway

Shao-Cong Sun, M. Waterfield, Minying Zhang, 2004, Molecular and Cellular Biology.

IκB Kinases Serve as a Target of CD28 Signaling*

E. Harhaj, Shao-Cong Sun, 1998, The Journal of Biological Chemistry.

Activation of NF-κB by Phosphatase Inhibitors Involves the Phosphorylation of IκBα at Phosphatase 2A-sensitive Sites (*)

E. Harhaj, Shao-Cong Sun, S. Maggirwar, 1995, The Journal of Biological Chemistry.

Targeting signaling factors for degradation, an emerging mechanism for TRAF functions

Shao-Cong Sun, Xiao-Dong Yang, 2015, Immunological reviews.

The noncanonical NF‐κB pathway

Shao-Cong Sun, 2012, Immunological reviews.

Defective feedback regulation of NF-κB underlies Sjögren’s syndrome in mice with mutated κB enhancers of the IκBα promoter

Huamin Wang, J. Fleming, P. Chiao, 2010, Proceedings of the National Academy of Sciences.

New insights into NF-kappaB regulation and function.

S. Ley, Shao-Cong Sun, 2008, Trends in immunology.

HTLV-2 Tax Immortalizes Human CD4+ Memory T Lymphocytes by Oncogenic Activation and Dysregulation of Autophagy*

Thomas P. Loughran, Di Xiang, Yoshinori Takahashi, 2012, The Journal of Biological Chemistry.

Deregulation of NF-κB and its upstream kinases in cancer

G. Xiao, Shao-Cong Sun, 2003, Cancer and Metastasis Reviews.

Domain-specific Interaction with the IκB Kinase (IKK) Regulatory Subunit IKKγ Is an Essential Step in Tax-mediated Activation of IKK*

E. Harhaj, G. Xiao, Shao-Cong Sun, 2000, The Journal of Biological Chemistry.

Activation of I-κB kinase by the HTLV type 1 Tax protein: Mechanistic insights into the adaptor function of IKKγ

E. Harhaj, G. Xiao, Shao-Cong Sun, 2000 .

The NF-κB Signaling Pathway Is Not Required for Fas Ligand Gene Induction but Mediates Protection from Activation-induced Cell Death*

G. Xiao, Shao-Cong Sun, M. Cvijic, 2000, The Journal of Biological Chemistry.

Epigenetic activation during T helper 17 cell differentiation is mediated by Tripartite motif containing 28

Shao-Cong Sun, W. Jin, Y. Liu, 2018, Nature Communications.

Deregulation of Tpl2 and NF-kappaB signaling and induction of macrophage apoptosis by the anti-depressant drug lithium.

Shao-Cong Sun, Minying Zhang, W. Jin, 2009, Cellular signalling.

Bcl-2 Prevents CD95 (Fas/APO-1)-induced Degradation of Lamin B and Poly(ADP-ribose) Polymerase and Restores the NF-κB Signaling Pathway*

M. Mandal, S. Kaufmann, Shao-Cong Sun, 1996, The Journal of Biological Chemistry.

Loss of c‐Kit and bone marrow failure upon conditional removal of the GATA‐2 C‐terminal zinc finger domain in adult mice

Ying Ma, Shao-Cong Sun, S. Ullrich, 2016, European journal of haematology.

TBKBP1 and TBK1 form a growth factor signaling axis mediating immunosuppression and tumorigenesis

Shao-Cong Sun, Xuhong Cheng, Yanchuan Li, 2019, Nature Cell Biology.

The E3 ubiquitin ligase Peli1 regulates the metabolic actions of mTORC1 to suppress antitumor T cell responses

Shao-Cong Sun, Lingyun Zhang, Xuhong Cheng, 2020, The EMBO journal.

TRAF3 regulates the effector function of regulatory T cells and humoral immune responses

Hongbo Hu, Jae-Hoon Chang, Shao-Cong Sun, 2014, The Journal of experimental medicine.

β-TrCP binding and processing of NF-κB2/p100 involve its phosphorylation at serines 866 and 870

Shao-Cong Sun, Minying Zhang, Chunyang Liang, 2006 .

Peli: a family of signal-responsive E3 ubiquitin ligases mediating TLR signaling and T-cell tolerance

Shao-Cong Sun, W. Jin, Mikyoung Chang, 2012, Cellular and Molecular Immunology.

Binding of c-Rel to STAT5 target sequences in HTLV-I-transformed T cells

E. Harhaj, Shao-Cong Sun, M. Uhlik, 1999, Oncogene.

Tumor Necrosis Factor Receptor-Associated Factor Regulation of Nuclear Factor κB and Mitogen-Activated Protein Kinase Pathways

Shao-Cong Sun, Jian-Hong Shi, 2018, Front. Immunol..

Verteporfin Inhibits PD-L1 through Autophagy and the STAT1–IRF1–TRIM28 Signaling Axis, Exerting Antitumor Efficacy

G. Mills, Z. Ding, Yiling Lu, 2020, Cancer Immunology Research.

Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 antiinflammatory activity in hematopoiesis

Erika J. Thompson, Jing Wang, G. Garcia-Manero, 2018, Proceedings of the National Academy of Sciences.

Cell type-specific function of TRAF2 and TRAF3 in regulating type I IFN induction

Shao-Cong Sun, Baoyu Zhao, Pingwei Li, 2019, Cell & Bioscience.

Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells

S. Akira, M. Pasparakis, Hongbo Hu, 2012, Nature Immunology.

Retroviral oncoprotein Tax deregulates NF‐κB by activating Tak1 and mediating the physical association of Tak1–IKK

Shao-Cong Sun, Xuefeng Wu, 2007, EMBO reports.

Noncanonical NF-κB regulates inducible costimulator (ICOS) ligand expression and T follicular helper cell development

Hongbo Hu, Shao-Cong Sun, W. Jin, 2011, Proceedings of the National Academy of Sciences.

Genetic Evidence for the Essential Role of β-Transducin Repeat-containing Protein in the Inducible Processing of NF-κB2/p100*

A. Fong, Shao-Cong Sun, 2002, The Journal of Biological Chemistry.

TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival

Shao-Cong Sun, Lingyun Zhang, Xuhong Cheng, 2018, Nature Communications.

Mutual regulation between deubiquitinase CYLD and retroviral oncoprotein Tax

Shao-Cong Sun, Minying Zhang, Xuefeng Wu, 2011, Cell & Bioscience.

Regulation of NF-κB2/p100 processing by its nuclear shuttling

Shao-Cong Sun, G. Liao, Gongxian Liao, 2003, Oncogene.

Activation of NF-kappaB by HTLV-I and implications for cell transformation.

S. Yamaoka, Shao-Cong Sun, 2005, Oncogene.

TRPM2 is an ion channel that modulates hematopoietic cell death through activation of caspases and PARP cleavage.

J. Cheung, L. Penn, D. Carey, 2006, American journal of physiology. Cell physiology.

Regulation of natural killer T‐cell development by deubiquitinase CYLD

Shao-Cong Sun, Dapeng Zhou, R. H. Bonneau, 2010, The EMBO journal.

HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains

Hong-Gang Wang, Shao-Cong Sun, T. Loughran, 2013, Oncogene.

IkappaB kinase is an essential component of the Tpl2 signaling pathway.

Shao-Cong Sun, M. Waterfield, Minying Zhang, 2004, Molecular and cellular biology.

Constitutive Dephosphorylation and Activation of a Member of the Nuclear Factor of Activated T Cells, NF-AT1, in Tax-expressing and Type I Human T-cell Leukemia Virus-infected Human T Cells*

E. Harhaj, S. Sun, Shao-Cong Sun, 1997, The Journal of Biological Chemistry.

Intestinal Epithelial TBK1 Prevents Differentiation of T-helper 17 Cells and Tumorigenesis in Mice.

Y. Qi, Jing Wang, Shao-Cong Sun, 2020, Gastroenterology.

CD2AP/SHIP1 Complex Positively Regulates Plasmacytoid Dendritic Cell Receptor Signaling by Inhibiting the E3 Ubiquitin Ligase Cbl

J. Qin, Shao-Cong Sun, W. Cao, 2012, The Journal of Immunology.

CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6

Shao-Cong Sun, R. Aneja, J. Ran, 2014, Cell Research.

The kinase TBK1 functions in dendritic cells to regulate T cell homeostasis, autoimmunity, and antitumor immunity

D. Levy, Hongbo Hu, Shao-Cong Sun, 2017, The Journal of experimental medicine.

Study of T-cell signaling by somatic cell mutagenesis and complementation cloning.

G. Xiao, Shao-Cong Sun, M. Cvijic, 2003, Journal of immunological methods.

The deubiquitinase Otub1 controls the activation of CD8 T cells and NK cells by regulating IL-15-mediated priming

Jing Wang, Shao-Cong Sun, G. Manyam, 2019, Nature Immunology.

RKIP inhibits NF‐κB in cancer cells by regulating upstream signaling components of the IκB kinase complex

R. Trumbly, Shao-Cong Sun, K. Yeung, 2010, FEBS letters.

Lymphatic endothelial cells regulate B-cell homing to lymph nodes via a NIK-dependent mechanism

Shao-Cong Sun, Lingyun Zhang, Xuhong Cheng, 2019, Cellular & Molecular Immunology.

T cell development involves TRAF3IP3-mediated ERK signaling in the Golgi

Hongbo Hu, James Y. H. Li, Shao-Cong Sun, 2015, The Journal of experimental medicine.

Activation of NF-κB by the Human T Cell Leukemia Virus Type I Tax Oncoprotein Is Associated with Ubiquitin-dependent Relocalization of IκB Kinase*

E. Harhaj, Shao-Cong Sun, Nicole S. Harhaj, 2006, Journal of Biological Chemistry.

Activation of NF-kappa B by the human T cell leukemia virus type I Tax oncoprotein is associated with ubiquitin-dependent relocalization of I kappa B kinase.

E. Harhaj, Shao-Cong Sun, Nicole S. Harhaj, 2007, The Journal of biological chemistry.

Peli1 negatively regulates type I interferon induction and antiviral immunity in the CNS

Hongbo Hu, Shao-Cong Sun, Qiang Zou, 2015, Cell & Bioscience.

Proinflammatory TLR signaling is regulated by a TRAF2-dependent proteolysis mechanism in macrophages

Hongbo Hu, Shao-Cong Sun, W. Ge, 2014, Nature Communications.

New insight into the oncogenic mechanism of the retroviral oncoprotein Tax

Shao-Cong Sun, Hua Cheng, Tongwei Ren, 2012, Protein & Cell.

A20 restricts inflammation via ubiquitin binding

Shao-Cong Sun, 2020, Nature Immunology.

DYRK1a mediates BAFF-induced noncanonical NF-kB activation to promote autoimmunity and B cell leukemogenesis.

M. Konopleva, S. Jung, Shao-Cong Sun, 2021, Blood.

NIK signaling axis regulates dendritic cell function in intestinal immunity and homeostasis

Shao-Cong Sun, Y. Cong, H. Brightbill, 2018, Nature Immunology.

Differential effects of IκB molecules on tat-mediated transactivation of HIV-1 LTR

E. Harhaj, Shao-Cong Sun, J. Blaney, 1996 .

FGL2 promotes tumor progression in the CNS by suppressing CD103+ dendritic cell differentiation

R. Davis, G. Rao, A. Heimberger, 2019, Nature Communications.

Absence of Grail promotes CD8+ T cell anti-tumour activity

R. Nurieva, Divyendu Singh, L. Kwak, 2017, Nature Communications.

Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus

Shao-Cong Sun, Chaoming Mao, N. Shen, 2018, Nature Communications.

Metabolic control of regulatory T cell stability and function by TRAF3IP3 at the lysosome

Liming Lu, Yuzhou Chang, Lei Chen, 2018, The Journal of experimental medicine.

and PARP cleavage caspases hematopoietic cell death through activation of TRPM2 is an ion channel that modulates

T. Gudermann, J. Cheung, L. Penn, 2010 .

Epigenetic activation during T helper 17 cell differentiation is mediated by Tripartite motif containing 28

Shao-Cong Sun, W. Jin, Y. Liu, 2018, Nature Communications.

TBK1 as a regulator of autoimmunity and antitumor immunity

Shao-Cong Sun, Xiaoping Xie, Jian-Hong Shi, 2018, Cellular & Molecular Immunology.

Survival and maintenance of regulatory T cells require the kinase TAK1

Hongbo Hu, Jae-Hoon Chang, Shao-Cong Sun, 2015, Cellular and Molecular Immunology.

TRAF 3 regulates the effector function of regulatory T cells and humoral immune responses

Hongbo Hu, Jae-Hoon Chang, Shao-Cong Sun, 2013 .

c-Cbl regulates dendritic cell activation

Payam Shahi, J. Levitt, Hongbo Hu, 2011 .

Pellino-1 Regulates Immune Responses to Haemophilus influenzae in Models of Inflammatory Lung Disease

Shao-Cong Sun, A. Condliffe, H. Marriott, 2019, Front. Immunol..

A Molecular Mechanism for Turning Off IRE1α Signaling during Endoplasmic Reticulum Stress

Shao-Cong Sun, M. Mariappan, Xia Li, 2020, bioRxiv.

Multiple Structural Domains within IκBα Are Required for Its Inducible Degradation by both Cytokines and Phosphatase Inhibitors

Shao-Cong Sun, M. Uhlik, S. Maggirwar, 1996 .

Cecropia immunoresponsive factor, an insect immunoresponsive factor with DNA-binding properties similar to nuclear-factor kappa B.

S. Sun, Shao-Cong Sun, I. Faye, 1992, European journal of biochemistry.

The Sec63/BiP complex suppresses higher-order oligomerization and RNase activity of IRE1α during ER stress

Shao-Cong Sun, M. Mariappan, Xia Li, 2020 .

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway.

W C Greene, W. Greene, S. Sun, 1993, Science.

Dependence and reversal of nitric oxide production on NF-kappa B in silica and lipopolysaccharide-induced macrophages.

F. Chen, S. Sun, Shao-Cong Sun, 1995, Biochemical and biophysical research communications.

kappa B-like motifs regulate the induction of immune genes in Drosophila.

D. Hultmark, C. Samakovlis, S. Sun, 1993, Journal of molecular biology.

Human T-cell leukemia virus type I Tax associates with and is negatively regulated by the NF-kappa B2 p100 gene product: implications for viral latency

W. Greene, S. Sun, Shao-Cong Sun, 1994, Molecular and cellular biology.

NF-kappaB transcription factors are involved in normal erythropoiesis.

S. Sun, Shao-Cong Sun, B. Miller, 1998, Blood.