V. Bottero

发表

Enhanced NF-kappaB activation and cellular function in macrophages lacking IkappaB kinase 1 (IKK1).

I. Verma, Qiutang Li, Qingxian Lu, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Enhanced NF-κB activation and cellular function in macrophages lacking IκB kinase 1 (IKK1)

Inder M. Verma, Qingxian Lu, I. Verma, 2005 .

UV-Mediated NF-κB Activation is Abolished in Deficient XPC/D Primary Fibroblasts

A. Muotri, V. Bottero, R. G. Correa, 2006, Cell cycle.

Meta-Analysis of Gene Expression Changes in the Blood of Patients with Mild Cognitive Impairment and Alzheimer’s Disease Dementia

J. Potashkin, V. Bottero, 2019, International journal of molecular sciences.

Dissecting the Molecular Mechanisms of Neurodegenerative Diseases through Network Biology

Jose A. Santiago, J. Potashkin, V. Bottero, 2017, Front. Aging Neurosci..

Bioinformatic Analysis Reveals Phosphodiesterase 4D-Interacting Protein as a Key Frontal Cortex Dementia Switch Gene

Jose A. Santiago, J. Potashkin, V. Bottero, 2020, International journal of molecular sciences.

IFI16 Restricts HSV-1 Replication by Accumulating on the HSV-1 Genome, Repressing HSV-1 Gene Expression, and Directly or Indirectly Modulating Histone Modifications

Karen E. Johnson, S. Dutta, B. Chandran, 2014, PLoS pathogens.

IκB-α, the NF-κB Inhibitory Subunit, Interacts with ANT, the Mitochondrial ATP/ADP Translocator*

J. Peyron, V. Bottero, P. Hofman, 2001, The Journal of Biological Chemistry.

Kaposi ’ s Sarcoma-Associated Herpesvirus Induces Nrf 2 Activation in Latently Infected Endothelial Cells through SQSTM 1 Phosphorylation and Interaction with Polyubiquitinated Keap 1

Karen E. Johnson, O. Gjyshi, B. Chandran, 2015 .

Kaposi's Sarcoma-Associated Herpesvirus Induces Nrf2 Activation in Latently Infected Endothelial Cells through SQSTM1 Phosphorylation and Interaction with Polyubiquitinated Keap1

Karen E. Johnson, O. Gjyshi, B. Chandran, 2014, Journal of Virology.

Gene therapy: Therapeutic gene causing lymphoma

I. Verma, V. Bottero, Manfred Schmidt, 2006, Nature.

Activation of Transcription Factor NF-κB Requires ELKS, an IκB Kinase Regulatory Subunit

A. Shevchenko, I. Verma, V. Bottero, 2004, Science.

Key Disease Mechanisms Linked to Amyotrophic Lateral Sclerosis in Spinal Cord Motor Neurons

Jose A. Santiago, J. Potashkin, V. Bottero, 2022, Frontiers in Molecular Neuroscience.

Kaposi's Sarcoma Associated Herpes Virus (KSHV) Induced COX-2: A Key Factor in Latency, Inflammation, Angiogenesis, Cell Survival and Invasion

B. Chandran, V. Bottero, M. Veettil, 2010, PLoS pathogens.

Transcriptomic and Network Meta-Analysis of Frontotemporal Dementias

Jose A. Santiago, J. Potashkin, V. Bottero, 2021, Frontiers in Molecular Neuroscience.

Essential role of tuberous sclerosis genes TSC1 and TSC2 in NF-kappaB activation and cell survival.

T. Hunter, I. Verma, V. Bottero, 2006, Cancer cell.

Essential role of tuberous sclerosis genes TSC 1 and TSC 2 in NFk B activation and cell survival

T. Hunter, I. Verma, V. Bottero, 2022 .

Evaluation of RNA Blood Biomarkers in the Parkinson’s Disease Biomarkers Program

Jose A. Santiago, J. Potashkin, V. Bottero, 2018, Front. Aging Neurosci..

PTPRC Expression in Blood is Downregulated in Parkinson's and Progressive Supranuclear Palsy Disorders.

Jose A. Santiago, J. Potashkin, V. Bottero, 2018, Journal of Parkinson's disease.

Monitoring NF-κB Transactivation Potential Via Real-Time PCR Quantification of IκB-α Gene Expression

V. Imbert, J. Peyron, V. Bottero, 2012, Molecular Diagnosis.

Reactive Oxygen Species (ROS) are Induced by Kaposi's

B. Chandran, V. Bottero, Sayan Chakraborty, 2012 .

Phosphorylation and Polyubiquitination of Transforming Growth Factor (cid:1) -Activated Kinase 1 Are Necessary for Activation of NF- (cid:2) B by the Kaposi’s Sarcoma-Associated Herpesvirus G Protein-Coupled Receptor (cid:1)

B. Chandran, V. Bottero, N. Sharma-Walia, 2011 .

Kaposi’s Sarcoma-Associated Herpesvirus-Induced Angiogenin Plays Roles in Latency via the Phospholipase C (cid:1) Pathway: Blocking Angiogenin Inhibits Latent Gene Expression and Induces the Lytic Cycle (cid:1) †

B. Chandran, V. Bottero, M. Veettil, 2011 .

Kaposi’s Sarcoma-Associated Herpesvirus Induces Sustained NF- (cid:2) B Activation during De Novo Infection of Primary Human Dermal Microvascular Endothelial Cells That Is Essential for Viral Gene Expression (cid:1)

B. Chandran, V. Bottero, M. Veettil, 2007 .

Computational identification of key genes that may regulate gene expression reprogramming in Alzheimer’s patients

Jose A. Santiago, J. Potashkin, V. Bottero, 2019, PloS one.

NF-kappaB modulation and ionizing radiation: mechanisms and future directions for cancer treatment.

Paul Van Houtte, N. Magné, P. Houtte, 2006, Cancer letters.

Activation of nuclear factor kappaB through the IKK complex by the topoisomerase poisons SN38 and doxorubicin: a brake to apoptosis in HeLa human carcinoma cells.

N. Magné, G. Milano, J. Peyron, 2001, Cancer research.

Kaposi's Sarcoma-Associated Herpesvirus Induces Nrf2 during De Novo Infection of Endothelial Cells to Create a Microenvironment Conducive to Infection

S. Dutta, O. Gjyshi, B. Chandran, 2014, PLoS pathogens.

Glutamate Secretion and Metabotropic Glutamate Receptor 1 Expression during Kaposi's Sarcoma-Associated Herpesvirus Infection Promotes Cell Proliferation

S. Dutta, O. Gjyshi, B. Chandran, 2014, PLoS pathogens.

Kaposi's Sarcoma-Associated Herpesvirus-Positive Primary Effusion Lymphoma Tumor Formation in NOD/SCID Mice Is Inhibited by Neomycin and Neamine Blocking Angiogenin's Nuclear Translocation

Karen E. Johnson, S. Dutta, B. Chandran, 2013, Journal of Virology.

Kaposi ’ s Sarcoma-Associated Herpesvirus Positive Primary Effusion Lymphoma Tumor 3 Formation in NOD / SCID Mice Is Inhibited by Neomycin and Neamine Blocking 4 Angiogenin ’ s Nuclear Translocation 5 6

Karen E. Johnson, S. Dutta, B. Chandran, 2013 .

Kaposi’s sarcoma-associated herpesvirus interacts with EphrinA2 receptor to amplify signaling essential for productive infection

B. Chandran, V. Bottero, M. Veettil, 2012, Proceedings of the National Academy of Sciences.

Kaposi's Sarcoma-Associated Herpesvirus-Induced Angiogenin Plays Roles in Latency via the Phospholipase Cγ Pathway: Blocking Angiogenin Inhibits Latent Gene Expression and Induces the Lytic Cycle

B. Chandran, V. Bottero, Mohanan Valiya Veettil, 2011, Journal of Virology.

Kaposi's Sarcoma-Associated Herpesvirus Induces Sustained NF-κB Activation during De Novo Infection of Primary Human Dermal Microvascular Endothelial Cells That Is Essential for Viral Gene Expression

B. Chandran, V. Bottero, M. Veettil, 2007, Journal of Virology.

Activation of Nuclear Factor κB through the IKK Complex by the Topoisomerase Poisons SN38 and Doxorubicin: A Brake to Apoptosis in HeLa Human Carcinoma Cells

N. Magné, G. Milano, J. Peyron, 2001 .

Kaposi sarcoma-associated herpes virus (KSHV) G protein-coupled receptor (vGPCR) activates the ORF50 lytic switch promoter: a potential positive feedback loop for sustained ORF50 gene expression.

B. Chandran, V. Bottero, M. Cannon, 2009, Virology.

IκB Kinase-Independent IκBα Degradation Pathway: Functional NF-κB Activity and Implications for Cancer Therapy

I. Verma, M. Ikawa, Qiutang Li, 2003, Molecular and Cellular Biology.

Blocking NF-κB activation in Jurkat leukemic T cells converts the survival agent and tumor promoter PMA into an apoptotic effector

P. Auberger, V. Imbert, J. Peyron, 2002, Oncogene.

Phosphorylation and Polyubiquitination of Transforming Growth Factor β-Activated Kinase 1 Are Necessary for Activation of NF-κB by the Kaposi's Sarcoma-Associated Herpesvirus G Protein-Coupled Receptor

B. Chandran, V. Bottero, N. Sharma-Walia, 2010, Journal of Virology.

Inhibition of the NF-κB survival pathway via caspase-dependent cleavage of the IKK complex scaffold protein and NF-κB essential modulator NEMO

G. Courtois, K. Schulze-Osthoff, P. Auberger, 2008, Cell Death and Differentiation.

Biological and Clinical Implications of Comorbidities in Parkinson’s Disease

Jose A. Santiago, J. Potashkin, V. Bottero, 2017, Front. Aging Neurosci..

IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection.

B. Chandran, V. Bottero, M. Veettil, 2011, Cell host & microbe.

Angiogenin functionally interacts with p53 and regulates p53 mediated apoptosis and cell survival

B. Chandran, V. Bottero, M. Veettil, 2011, Oncogene.

Rat liver injury following normothermic ischemia is prevented by a phosphinic matrix metalloproteinase inhibitor

P. Auberger, J. Gugenheim, V. Dive, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Phosphorylation of p53 by IκB kinase 2 promotes its degradation by β-TrCP

I. Verma, V. Bottero, V. Tergaonkar, 2009, Proceedings of the National Academy of Sciences.

Kaposi's sarcoma-associated herpesvirus induces sustained NF-kappaB activation during de novo infection of primary human dermal microvascular endothelial cells that is essential for viral gene expression.

B. Chandran, V. Bottero, M. Veettil, 2007, Journal of virology.

Kaposi's Sarcoma-Associated Herpesvirus Latency in Endothelial and B Cells Activates Gamma Interferon-Inducible Protein 16-Mediated Inflammasomes

M. A. Ansari, S. Dutta, B. Chandran, 2013, Journal of Virology.

NF-kappaB and the regulation of hematopoiesis.

I. Verma, S. Withoff, V. Bottero, 2006, Cell death and differentiation.

Kaposi's Sarcoma-Associated Herpesvirus Induces Sustained Levels of Vascular Endothelial Growth Factors A and C Early during In Vitro Infection of Human Microvascular Dermal Endothelial Cells: Biological Implications

B. Chandran, V. Bottero, M. Veettil, 2007, Journal of Virology.

Reactive Oxygen Species Are Induced by Kaposi's Sarcoma-Associated Herpesvirus Early during Primary Infection of Endothelial Cells To Promote Virus Entry

B. Chandran, V. Bottero, Sayan Chakraborty, 2012, Journal of Virology.

Transcriptomic and Network Analysis Identifies Shared and Unique Pathways across Dementia Spectrum Disorders

Jose A. Santiago, J. Potashkin, V. Bottero, 2020, International journal of molecular sciences.

A Comparison of Gene Expression Changes in the Blood of Individuals Consuming Diets Supplemented with Olives, Nuts or Long-Chain Omega-3 Fatty Acids

J. Potashkin, V. Bottero, 2020, Nutrients.

Angiogenin interacts with the plasminogen activation system at the cell surface of breast cancer cells to regulate plasmin formation and cell migration

Karen E. Johnson, S. Dutta, B. Chandran, 2014, Molecular oncology.

IFI16 Restricts HSV-1 Replication by Accumulating on the HSV-1 Genome, Repressing HSV-1 Gene Expression, and Directly or Indirectly Modulating Histone Modifications

Karen E. Johnson, S. Dutta, B. Chandran, 2014, PLoS pathogens.

NF-κB and the regulation of hematopoiesis

I. Verma, S. Withoff, V. Bottero, 2006, Cell Death and Differentiation.

Characterization of entry and infection of monocytic THP-1 cells by Kaposi's sarcoma associated herpesvirus (KSHV): role of heparan sulfate, DC-SIGN, integrins and signaling.

B. Chandran, V. Bottero, M. Veettil, 2010, Virology.

Lipid Rafts of Primary Endothelial Cells Are Essential for Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8-Induced Phosphatidylinositol 3-Kinase and RhoA-GTPases Critical for Microtubule Dynamics and Nuclear Delivery of Viral DNA but Dispensable for Binding and Entry

B. Chandran, V. Bottero, M. Veettil, 2007, Journal of Virology.

Transcriptomic and Network Analysis Highlight the Association of Diabetes at Different Stages of Alzheimer’s Disease

Jose A. Santiago, J. Potashkin, V. Bottero, 2019, Front. Neurosci..

COX-2/PGE2: molecular ambassadors of Kaposi's sarcoma-associated herpes virus oncoprotein-v-FLIP

V. Bottero, N. Sharma-Walia, N. Kerur, 2012, Oncogenesis.

Human-Induced Neurons from Presenilin 1 Mutant Patients Model Aspects of Alzheimer’s Disease Pathology

C. Briggs, V. Bottero, O. Singer, 2020, International journal of molecular sciences.

Monitoring NF-kappa B transactivation potential via real-time PCR quantification of I kappa B-alpha gene expression.

V. Imbert, J. Peyron, V. Bottero, 2003, Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology.

Key Disease Mechanisms Linked to Alzheimer’s Disease in the Entorhinal Cortex

J. Potashkin, V. Bottero, J. P. Quinn, 2021, International journal of molecular sciences.

Correction: IFI16 Restricts HSV-1 Replication by Accumulating on the HSV-1 Genome, Repressing HSV-1 Gene Expression, and Directly or Indirectly Modulating Histone Modifications

Karen E. Johnson, S. Dutta, B. Chandran, 2018, PLoS pathogens.

Inhibition of the NF-kappaB survival pathway via caspase-dependent cleavage of the IKK complex scaffold protein and NF-kappaB essential modulator NEMO.

G. Courtois, K. Schulze-Osthoff, P. Auberger, 2008, Cell death and differentiation.

Kaposi's Sarcoma-Associated Herpesvirus Upregulates Angiogenin during Infection of Human Dermal Microvascular Endothelial Cells, Which Induces 45S rRNA Synthesis, Antiapoptosis, Cell Proliferation, Migration, and Angiogenesis

B. Chandran, V. Bottero, M. Veettil, 2009, Journal of Virology.

ESCRT-0 Component Hrs Promotes Macropinocytosis of Kaposi's Sarcoma-Associated Herpesvirus in Human Dermal Microvascular Endothelial Cells

M. A. Ansari, O. Gjyshi, B. Chandran, 2016, Journal of Virology.

Activation of Transcription Factor NF-κB Requires ELKS, an IκB Kinase Regulatory Subunit

A. Shevchenko, I. Verma, V. Bottero, 2004, Science.