Chih-Yang Huang

发表

CREB Negatively Regulates IGF2R Gene Expression and Downstream Pathways to Inhibit Hypoxia-Induced H9c2 Cardiomyoblast Cell Death

Wei-Kung Chen, W. Kuo, Dennis Jine-Yuan Hsieh, 2015, International journal of molecular sciences.

Mitotic arrest induced in human DU145 prostate cancer cells in response to KHC‐4 treatment

S. Kuo, Dennis Jine-Yuan Hsieh, Chih-Yang Huang, 2016, Environmental toxicology.

Mir-100-5p Enhanced Cell Cycle-Mediated Chemoresistance Through Modulating Ctdspl/Prb/E2f1 Signaling Pathway in Oxaliplatin-Resistant Colorectal Cancer

T. Shih, W. Kuo, Tsung‐Jung Ho, 2022, SSRN Electronic Journal.

Zanthoxylum avicennae extracts inhibit cell proliferation through protein phosphatase 2A activation in HA22T human hepatocellular carcinoma cells in vitro and in vivo.

F. Tsai, W. Kuo, Chih-Yang Huang, 2012, International journal of molecular medicine.

ZAK re-programs atrial natriuretic factor expression and induces hypertrophic growth in H9c2 cardiomyoblast cells.

W. Kuo, Chih-Yang Huang, P. Chueh, 2004, Biochemical and biophysical research communications.

Inhibition of NF‐κB and metastasis in irinotecan (CPT‐11)‐resistant LoVo colon cancer cells by thymoquinone via JNK and p38

Ray-Jade Chen, W. Kuo, Tsung‐Jung Ho, 2017, Environmental toxicology.

PKCα expression regulated by Elk-1 and MZF-1 in human HCC cells

Y. Hsieh, Chih-Yang Huang, Jer‐Yuh Liu, 2006 .

Lactoferrin Increases Antioxidant Activities and Ameliorates Hepatic Fibrosis in Lupus-Prone Mice Fed with a High-Cholesterol Diet.

B. Tzang, Chih-Yang Huang, Hung-An Chen, 2016, Journal of medicinal food.

Protective effect of Fisetin against angiotensin II-induced apoptosis by activation of IGF-IR-PI3K-Akt signaling in H9c2 cells and spontaneous hypertension rats.

Ray-Jade Chen, V. Viswanadha, Chih-Yang Huang, 2019, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Serum MMP-9 activity as a diagnosing marker for the developing heart failure of post MI patients.

Chieh-Hsi Wu, Shin-Da Lee, W. Kuo, 2006, The Chinese journal of physiology.

Resveratrol enhanced FOXO3 phosphorylation via synergetic activation of SIRT1 and PI3K/Akt signaling to improve the effects of exercise in elderly rat hearts

W. Kuo, P. Pai, Tsung‐Jung Ho, 2014, AGE.

Exercise training enhanced SIRT1 longevity signaling replaces the IGF1 survival pathway to attenuate aging-induced rat heart apoptosis

W. Kuo, P. Pai, Tsung‐Jung Ho, 2014, AGE.

Bloating mechanism of the mixture of thin-film transistor liquid-crystal display waste glass and basic oxygen furnace slag

Chih-Yang Huang, Kung-cheh Li, Chen-Shiuan Fan, 2014 .

Neferine from Nelumbo nucifera modulates oxidative stress and cytokines production during hypoxia in human peripheral blood mononuclear cells.

P. Poornima, Chih-Yang Huang, V. V. Padma, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Arecoline induces heart injure via Fas/Fas ligand apoptotic pathway in heart of Sprague–Dawley rat

Ray-Jade Chen, Chih-Yang Huang, Wen-Yuan Lin, 2021, Environmental toxicology.

Betel Nut Chewing Is Strongly Associated With General and Central Obesity in Chinese Male Middle‐aged Adults

Chih-Yang Huang, F. Pi‐Sunyer, Chia-Ing Li, 2009, Obesity.

Betel nut chewing is associated with increased risk of cardiovascular disease and all-cause mortality in Taiwanese men.

Long‐Teng Lee, Kuo-Chin Huang, Chih-Yang Huang, 2008, The American journal of clinical nutrition.

Acute hypoxic preconditioning prevents palmitic acid‐induced cardiomyocyte apoptosis via switching metabolic GLUT4‐glucose pathway back to CD36‐fatty acid dependent

Ray-Jade Chen, W. Kuo, Tsung‐Jung Ho, 2018, Journal of cellular biochemistry.

E4BP4 is a cardiac survival factor and essential for embryonic heart development

F. Tsai, W. Kuo, Dennis Jine-Yuan Hsieh, 2010, Molecular and Cellular Biochemistry.

TRAF6 Restricts p53 Mitochondrial Translocation, Apoptosis, and Tumor Suppression.

F. Tsai, K. Watabe, Xiaohong Xu, 2016, Molecular cell.

Resistin protects against 6‐hydroxydopamine‐induced cell death in dopaminergic‐like MES23.5 cells

Chih-Yang Huang, T. Tan, W. Yeh, 2013, Journal of cellular physiology.

The profile of cardiac cytochrome c oxidase (COX) expression in an accelerated cardiac-hypertrophy model.

Chieh-Hsi Wu, Shin-Da Lee, W. Kuo, 2005, Journal of biomedical science.

Thymoquinone induces apoptosis in oral cancer cells through p38β inhibition.

Ray-Jade Chen, Chih-Yang Huang, Wei-Jen Ting, 2013, The American journal of Chinese medicine.

HIV-1 Vpr Triggers Mitochondrial Destruction by Impairing Mfn2-Mediated ER-Mitochondria Interaction

S. Chiang, Chih-Yang Huang, Tzei-Yi Lin, 2012, PloS one.

Neferine prevents autophagy induced by hypoxia through activation of Akt/mTOR pathway and Nrf2 in muscle cells.

P. Poornima, Chih-Yang Huang, V. V. Padma, 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Isolation and determination of four potential antimicrobial components from Pseudomonas aeruginosa extracts

Chih-Yang Huang, Wei-Jen Ting, Ziyong Sun, 2017, International journal of medical sciences.

Carthamus tinctorius L. prevents LPS-induced TNFalpha signaling activation and cell apoptosis through JNK1/2-NFkappaB pathway inhibition in H9c2 cardiomyoblast cells.

F. Tsai, Chih-Yang Huang, Chang-Hai Tsai, 2010, Journal of ethnopharmacology.

Akt mediates 17 -estradiol and/or estrogen receptor- inhibition of LPS-induced tumor necresis factor- expression and myocardial cell apoptosis by suppressing the JNK1/2-NF B pathway

F. Tsai, B. Tzang, W. Kuo, 2009 .

Akt mediates 17β-estradiol and/or estrogen receptor-α inhibition of LPS-induced tumor necresis factor-α expression and myocardial cell apoptosis by suppressing the JNK1/2-NFκB pathway

F. Tsai, B. Tzang, W. Kuo, 2009, Journal of cellular and molecular medicine.

Lipopolysaccharide induces cellular hypertrophy through calcineurin/NFAT-3 signaling pathway in H9c2 myocardiac cells

W. Kuo, Chih-Yang Huang, Chung-Jung Liu, 2008, Molecular and Cellular Biochemistry.

Lupeol suppresses migration and invasion via p38/MAPK and PI3K/Akt signaling pathways in human osteosarcoma U-2 OS cells

Jai-Sing Yang, Jing-Gung Chung, F. Tsai, 2019, Bioscience, biotechnology, and biochemistry.

Efficacy of epigallocatechin-3-gallate and Amla (Emblica officinalis) extract for the treatment of diabetic-uremic patients.

F. Tsai, Chih-Yang Huang, Hsi-Chin Wu, 2011, Journal of medicinal food.

Inhibitory effect of alpinate Oxyphyllae fructus extracts on Ang II-induced cardiac pathological remodeling-related pathways in H9c2 cardiomyoblast cells

F. Tsai, W. Kuo, Tsung‐Jung Ho, 2013 .

Oxaliplatin resistance in colorectal cancer cells is mediated via activation of ABCG2 to alleviate ER stress induced apoptosis

W. Kuo, Chih-Yang Huang, Ming-Cheng Chen, 2018, Journal of cellular physiology.

SHSST-cyclodextrin complex inhibits TGF-β/Smad3/CTGF to a greater extent than silymarin in a rat model of carbon tetrachloride-induced liver injury.

Cheng-Hsun Yang, F. Tsai, Chih-Yang Huang, 2015, Molecular medicine reports.

Effects of short-term detraining on measures of obesity and glucose tolerance in elite athletes

Shin-Da Lee, Chih-Yang Huang, Yung-Yang Liu, 2008, Journal of sports sciences.

Cardiac injury protection from mouse bone marrow stromal cells with in utero transplantation followed by secondary postnatal boost.

Chih-Yang Huang, M. Ma, S. Chou, 2011, The Chinese journal of physiology.

Distinct population of highly malignant cells in a head and neck squamous cell carcinoma cell line established by xenograft model

S. Chiou, Chih-Yang Huang, Shu-Chun Lin, 2009, Journal of Biomedical Science.

GABA tea prevents cardiac fibrosis by attenuating TNF-alpha and Fas/FasL-mediated apoptosis in streptozotocin-induced diabetic rats.

F. Tsai, W. Kuo, Chih-Yang Huang, 2014, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Anti-Apoptotic and Pro-Survival Effect of Alpinate Oxyphyllae Fructus (AOF) in a d-Galactose-Induced Aging Heart

Ray-Jade Chen, W. Kuo, Hsin-Nung Chang, 2016, International journal of molecular sciences.

Apicidin-Resistant HA22T Hepatocellular Carcinoma Cells strongly activated the Wnt/β-Catenin Signaling Pathway and MMP-2 Expression via the IGF-IR/PI3K/Akt Signaling Pathway Enhancing Cell Metastatic Effect

F. Tsai, Tsung‐Jung Ho, Chih-Yang Huang, 2013, Bioscience, biotechnology, and biochemistry.

Cataract increases the risk of peripheral artery occlusive disease: A nationwide population-based cohort study with propensity score.

Chih-Yang Huang, Kuan-Cheng Chang, Cheng-Li Lin, 2016, International journal of cardiology.

Exercise training enhances cardiac IGFI-R/PI3K/Akt and Bcl-2 family associated pro-survival pathways in streptozotocin-induced diabetic rats.

H. Ou, Shin-Da Lee, Tsung‐Jung Ho, 2013, International journal of cardiology.

Hepatoprotective Effects of Ixora parviflora Extract against Exhaustive Exercise-Induced Oxidative Stress in Mice

Chih-Yang Huang, M. Hsu, Wen-Ching Huang, 2013, Molecules.

Discipline-specific insulin sensitivity in athletes.

Shin-Da Lee, Chih-Yang Huang, P. Hsieh, 2009, Nutrition.

Treatment with 17β-Estradiol Reduced Body Weight and the Risk of Cardiovascular Disease in a High-Fat Diet-Induced Animal Model of Obesity

P. Pai, Kuan-Ho Lin, V. Viswanadha, 2017, International journal of molecular sciences.

Antiapoptotic effect of exercise training on ovariectomized rat hearts.

Shin-Da Lee, Tsung‐Jung Ho, Chih-Yang Huang, 2016, Journal of applied physiology.

Effects of 17beta‐estradiol on cardiac apoptosis in ovariectomized rats

Shin-Da Lee, Chih-Yang Huang, C. Kuo, 2010, Cell biochemistry and function.

Cardiac Fas-dependent and mitochondria-dependent apoptosis in ovariectomized rats.

Shin-Da Lee, W. Kuo, Chih-Yang Huang, 2008, Maturitas.

Potential phytoestrogen alternatives exert cardio-protective mechanisms via estrogen receptors

W. Kuo, L. Pan, Chih-Yang Huang, 2017, BioMedicine.

Mechanisms governing the protective effect of 17β-estradiol and estrogen receptors against cardiomyocyte injury

F. Tsai, Chih-Yang Huang, Chang-Hai Tsai, 2011 .

ZAKβ antagonizes and ameliorates the cardiac hypertrophic and apoptotic effects induced by ZAKα

W. Kuo, Tsung‐Jung Ho, V. Viswanadha, 2016, Cell biochemistry and function.

High-density lipoprotein ameliorates palmitic acid-induced lipotoxicity and oxidative dysfunction in H9c2 cardiomyoblast cells via ROS suppression

Jai-Sing Yang, Jing-Gung Chung, F. Tsai, 2019, Nutrition & Metabolism.

Cardiac apoptosis induced under high glucose condition involves activation of IGF2R signaling in H9c2 cardiomyoblasts and streptozotocin-induced diabetic rat hearts.

Ray-Jade Chen, V. Viswanadha, Chih-Yang Huang, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Tinospora cordifolia extract attenuates cadmium-induced biochemical and histological alterations in the heart of male Wistar rats.

V. Dhivya, Chih-Yang Huang, V. V. Padma, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Ellagic acid inhibits oxidized low-density lipoprotein (OxLDL)-induced metalloproteinase (MMP) expression by modulating the protein kinase C-α/extracellular signal-regulated kinase/peroxisome proliferator-activated receptor γ/nuclear factor-κB (PKC-α/ERK/PPAR-γ/NF-κB) signaling pathway in endothelia

W. Sheu, H. Ou, Kun-Ling Tsai, 2011, Journal of agricultural and food chemistry.

FOXC1 Regulation of miR-31-5p Confers Oxaliplatin Resistance by Targeting LATS2 in Colorectal Cancer

W. Kuo, V. Viswanadha, Chih-Yang Huang, 2019, Cancers.

CCN6 enhances ICAM‐1 expression and cell motility in human chondrosarcoma cells

F. Tsai, Chih-Yang Huang, Chang-Hai Tsai, 2012, Journal of cellular physiology.

Mesenchymal Stem Cell Insights: Prospects in Hematological Transplantation

F. Tsai, W. Kuo, Dennis Jine-Yuan Hsieh, 2013, Cell transplantation.

Andrographolide mitigates cardiac apoptosis to provide cardio‐protection in high‐fat‐diet‐induced obese mice

W. Kuo, Kuan-Ho Lin, V. Viswanadha, 2020, Environmental toxicology.

Cardiac hypertrophy-related pathways in obesity.

F. Tsai, B. Tzang, Shin-Da Lee, 2014, The Chinese journal of physiology.

Possible pathophysiology of heart failure in obesity: Cardiac apoptosis

Shin-Da Lee, Chih-Yang Huang, 2012 .

The coexistence of nocturnal sustained hypoxia and obesity additively increases cardiac apoptosis.

F. Tsai, Shin-Da Lee, W. Kuo, 2008, Journal of applied physiology.

More Activated Cardiac Mitochondrial‐dependent Apoptotic Pathway in Obese Zucker Rats

B. Tzang, Shin-Da Lee, W. Kuo, 2007, Obesity.

Moderate exercise training attenuates aging-induced cardiac inflammation, hypertrophy and fibrosis injuries of rat hearts

Ray-Jade Chen, W. Kuo, Dennis Jine-Yuan Hsieh, 2015, Oncotarget.

Cystamine ameliorates ventricular hypertrophy associated with modulation of IL-6-mediated signaling in lupus-prone mice.

B. Tzang, Chih-Yang Huang, T. Hsu, 2013, Life sciences.

Hyperphosphate-Induced Myocardial Hypertrophy through the GATA-4/NFAT-3 Signaling Pathway Is Attenuated by ERK Inhibitor Treatment

Shih-Yi Lin, Dennis Jine-Yuan Hsieh, Chih-Yang Huang, 2015, Cardiorenal Medicine.

Effects of lactic acid bacteria on cardiac apoptosis are mediated by activation of the phosphatidylinositol-3 kinase/AKT survival-signalling pathway in rats fed a high-fat diet.

Chih-Yang Huang, Cheng-Chih Tsai, Pei-Pei Lin, 2015, International journal of molecular medicine.

Insulin-like growth factor-induced hypertrophy of cultured adult rat cardiomyocytes is L-type calcium-channel-dependent

Chih-Yang Huang, D. E. Buetow, Ling-Yang Hao, 2002, Molecular and Cellular Biochemistry.

Distinct Subpopulations of Head and Neck Cancer Cells with Differential Intracellular ROS Exhibiting Diverse Chemoresistance , Stemness and Proliferative Activity

Chih-Yang Huang, S. Chou, Cheng-Chieh Yang, 2014 .

Tissue engineering stent model with long fiber-reinforced thermoplastic technique

Chih-Yang Huang, Yueh-Sheng Chen, Mei-Chen Lin, 2020, Journal of Materials Science: Materials in Medicine.

Induction of apoptosis in human DU145 prostate cancer cells by KHC-4 treatment.

S. Kuo, Chih-Yang Huang, Tien-Huang Lin, 2014, The Chinese journal of physiology.

KHC-4 anti-cancer effects on human PC3 prostate cancer cell line.

Po-Yuan Chen, S. Kuo, Chih-Yang Huang, 2012, The American journal of Chinese medicine.

Galangin Reverses H2O2-Induced Dermal Fibroblast Senescence via SIRT1-PGC-1α/Nrf2 Signaling

W. Kuo, Chih-Yang Huang, Jian-Jr Lee, 2022, International journal of molecular sciences.

Taiwanin E Induces Cell Cycle Arrest and Apoptosis in Arecoline/4-NQO-Induced Oral Cancer Cells Through Modulation of the ERK Signaling Pathway

Y. Chao, Y. Kuo, V. Viswanadha, 2019, Front. Oncol..

Iron status and cardiovascular risk factors in patients with haemodialysis versus patients with ischaemic heart disease

Chieh-Hsi Wu, Shin-Da Lee, W. Kuo, 2009, Nephrology.

Pro-inflammatory states and IGF-I level in ischemic heart disease with low or high serum iron.

Shin-Da Lee, W. Kuo, Chih-Yang Huang, 2006, Clinica chimica acta; international journal of clinical chemistry.

Association between frailty and subclinical peripheral vascular disease in a community‐dwelling geriatric population: Taichung Community Health Study for Elders

Chih-Yang Huang, C. Chou, C. Liu, 2015, Geriatrics & gerontology international.

Diallyl Trisulfide Suppresses High-Glucose-Induced Cardiomyocyte Apoptosis by Targeting Reactive Oxygen Species-Mediated Hypoxia-Inducible Factor-1α/Insulin-like Growth Factor Binding Protein 3 Activation.

W. Kuo, Kuan-Ho Lin, V. Viswanadha, 2021, Journal of agricultural and food chemistry.

Angiotensin-(1-7) attenuated long-term hypoxia-stimulated cardiomyocyte apoptosis by inhibiting HIF-1α nuclear translocation via Mas receptor regulation

W. Kuo, Dennis Jine-Yuan Hsieh, Tsung‐Jung Ho, 2016, Growth factors.

Long-term hypoxia exposure enhanced IGFBP-3 protein synthesis and secretion resulting in cell apoptosis in H9c2 myocardial cells

W. Kuo, Dennis Jine-Yuan Hsieh, Tsung‐Jung Ho, 2015, Growth factors.

Differentiation of Embryonic Stem Cells into Cardiomyocytes Used to Investigate the Cardioprotective Effect of Salvianolic Acid B through BNIP3 Involved Pathway

Chih-Yang Huang, Shinn-Zong Lin, W. Shyu, 2015, Cell transplantation.

Hypoxia-induced compensatory effect as related to Shh and HIF-1α in ischemia embryo rat heart

Chieh-Hsi Wu, F. Tsai, W. Kuo, 2008, Molecular and Cellular Biochemistry.

Anion exchanger inhibitor DIDS induces human poorly-differentiated malignant hepatocellular carcinoma HA22T cell apoptosis

Y. Hsieh, Chih-Yang Huang, Hsi-Chin Wu, 2007, Molecular and Cellular Biochemistry.

Protective effect of HDL on NADPH oxidase-derived super oxide anion mediates hypoxia-induced cardiomyocyte apoptosis

Ray-Jade Chen, H. Ou, W. Kuo, 2017, PloS one.

Leptin increases motility and integrin up‐regulation in human prostate cancer cells

F. Tsai, Chih-Yang Huang, Hsi-Chin Wu, 2011, Journal of cellular physiology.

Hypoxia Augments Increased HIF-1α and Reduced Survival Protein p-Akt in Gelsolin (GSN)-Dependent Cardiomyoblast Cell Apoptosis

Chih-Yang Huang, Chia-Yao Shen, Wei-Jen Ting, 2016, Cell Biochemistry and Biophysics.

Hypoxia Augments Increased HIF-1α and Reduced Survival Protein p-Akt in Gelsolin (GSN)-Dependent Cardiomyoblast Cell Apoptosis

Chih-Yang Huang, Chia-Yao Shen, Wei-Jen Ting, 2016, Cell Biochemistry and Biophysics.

Gelsolin (GSN) induces cardiomyocyte hypertrophy and BNP expression via p38 signaling and GATA-4 transcriptional factor activation

F. Tsai, P. Pai, Tsung‐Jung Ho, 2014, Molecular and Cellular Biochemistry.

Hepatocellular Carcinoma Cells Regulated Invasion in Human − α Protein Kinase C p 38 Mitogen-Activated Protein Kinase Pathway Is Involved in

Y. Hsieh, Chih-Yang Huang, Jer‐Yuh Liu, 2007 .

Plasma levels of matrix metalloproteinase-2 and -9 in male and female patients with cirrhosis of different aetiologies

Chih-Yang Huang, Ming-Nan Lin, J. Tsai, 2015, Journal of Clinical Pathology.

Activation of IFN-γ/STAT/IRF-1 in Hepatic Responses to Klebsiella pneumoniae Infection

Y. Lai, Chih-Yang Huang, M. Chiang, 2013, PloS one.

Esculetin Ameliorates Carbon Tetrachloride-Mediated Hepatic Apoptosis in Rats

Chih-Yang Huang, Jung-Chun Liao, Wen-Te Chang, 2011, International journal of molecular sciences.

Diosmin induces cell apoptosis through protein phosphatase 2A activation in HA22T human hepatocellular carcinoma cells and blocks tumour growth in xenografted nude mice

F. Tsai, W. Kuo, Chih-Yang Huang, 2012 .

Anti-apoptotic and Pro-survival Effects of Food Restriction on High-Fat Diet-Induced Obese Hearts

Shin-Da Lee, Chih-Yang Huang, Yu-Jung Cheng, 2017, Cardiovascular Toxicology.

CHIP attenuates lipopolysaccharide‐induced cardiac hypertrophy and apoptosis by promoting NFATc3 proteasomal degradation

Ray-Jade Chen, W. Kuo, V. Viswanadha, 2019, Journal of cellular physiology.

Heat-killed Lactobacillus Reuteri GMNL-263 Prevents Epididymal Fat Accumulation and Cardiac Injury in High-Calorie Diet-Fed Rats

W. Kuo, Dennis Jine-Yuan Hsieh, Chih-Yang Huang, 2016, International journal of medical sciences.

Fisetin mediated apoptotic cell death in parental and Oxaliplatin/irinotecan resistant colorectal cancer cells in vitro and in vivo

L. Jeng, Tsung‐Jung Ho, Chih-Yang Huang, 2018, Journal of cellular physiology.

Cellular apoptosis and cardiac dysfunction in STZ‐induced diabetic rats attenuated by anthocyanins via activation of IGFI‐R/PI3K/Akt survival signaling

M. Fan, Chih-Yang Huang, Guei‐Jane Wang, 2017, Environmental toxicology.

Serum insulin-like growth factor-axis and matrix metalloproteinases in patients with rheumatic arthritis or rheumatic heart disease.

Shin-Da Lee, W. Kuo, Chih-Yang Huang, 2006, Clinica chimica acta; international journal of clinical chemistry.

Novel anti-aging herbal formulation Jing Si displays pleiotropic effects against aging associated disorders.

W. Kuo, Tsung‐Jung Ho, Chih-Yang Huang, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Exercise renovates H2S and Nrf2-related antioxidant pathways to suppress apoptosis in the natural ageing process of male rat cortex

Ray-Jade Chen, W. Kuo, Tsung‐Jung Ho, 2021, Biogerontology.

Garlic Oil Alleviates MAPKs- and IL-6-mediated Diabetes-related Cardiac Hypertrophy in STZ-induced DM Rats

F. Tsai, B. Tzang, W. Kuo, 2010, Evidence-based complementary and alternative medicine : eCAM.

Platycodin D Reverses Pathological Cardiac Hypertrophy and Fibrosis in Spontaneously Hypertensive Rats.

Yu Lin, W. Kuo, Chih-Yang Huang, 2018, The American journal of Chinese medicine.

Reduction of TLR 4 mRNA Stability and Protein Expressions through Inhibiting Cytoplasmic Translocation of HuR Transcription Factor by E 2 and / or ER α in LPS-Treated H 9 c 2 Cardiomyoblast Cells

M. Fan, F. Tsai, P. Pai, 2014 .

Growth-Promoting Effects of Quercetin on Peripheral Nerves in Rats

F. Tsai, Chih-Yang Huang, C. Yao, 2011, The International journal of artificial organs.

Diallyl Trisulfide (DATS) Suppresses AGE-Induced Cardiomyocyte Apoptosis by Targeting ROS-Mediated PKCδ Activation

W. Kuo, Dennis Jine-Yuan Hsieh, Chih-Yang Huang, 2020, International journal of molecular sciences.

Deep sea minerals prolong life span of streptozotocin‐induced diabetic rats by compensatory augmentation of the IGF‐I‐survival signaling and inhibition of apoptosis

W. Kuo, P. Pai, Tsung‐Jung Ho, 2016, Environmental toxicology.

Lactobacillus reuteri GMN-32 treatment reduces blood glucose concentrations and promotes cardiac function in rats with streptozotocin-induced diabetes mellitus

F. Tsai, Chih-Yang Huang, M. Shibu, 2014 .

Oral Lactobacillus reuteri GMN-32 treatment reduces blood glucose concentrations and promotes cardiac function in rats with streptozotocin-induced diabetes mellitus

F. Tsai, Chih-Yang Huang, M. Shibu, 2013, British Journal of Nutrition.

Bioactive dipeptide from potato protein hydrolysate combined with swimming exercise prevents high fat diet induced hepatocyte apoptosis by activating PI3K/Akt in SAMP8 mouse

Ray-Jade Chen, Tsung‐Jung Ho, Chih-Yang Huang, 2021, Molecular Biology Reports.

Tanshinone IIA Inhibits β-Catenin Nuclear Translocation and IGF-2R Activation via Estrogen Receptors to Suppress Angiotensin II-Induced H9c2 Cardiomyoblast Cell Apoptosis

Ray-Jade Chen, V. Viswanadha, Chih-Yang Huang, 2017, International journal of medical sciences.

Multi-Strain Probiotics Inhibit Cardiac Myopathies and Autophagy to Prevent Heart Injury in High-Fat Diet-Fed Rats

W. Kuo, P. Pai, Tsung‐Jung Ho, 2016, International journal of medical sciences.

Effect of acute DHEA administration on free testosterone in middle-aged and young men following high-intensity interval training

J. Ivy, Chih-Yang Huang, C. Kuo, 2013, European Journal of Applied Physiology.

E2/ER β inhibit ISO-induced cardiac cellular hypertrophy by suppressing Ca2+-calcineurin signaling

W. Kuo, V. Viswanadha, Chih-Yang Huang, 2017, PloS one.

Leu 27 IGF 2 plays an opposite r ole to IGF 1 to induce H 9 c 2 cardiomyoblast cell apoptosis via G a q signaling

Ray-Jade Chen, F. Tsai, Chih-Yang Huang, 2009 .

Leu27IGF2 plays an opposite role to IGF1 to induce H9c2 cardiomyoblast cell apoptosis via Galphaq signaling.

Ray-Jade Chen, F. Tsai, Chih-Yang Huang, 2009, Journal of molecular endocrinology.

Activation of insulin-like growth factor II receptor induces mitochondrial-dependent apoptosis through G(alpha)q and downstream calcineurin signaling in myocardial cells.

F. Tsai, B. Tzang, W. Kuo, 2009, Endocrinology.

Enhancement of AG1024-induced H9c2 cardiomyoblast cell apoptosis via the interaction of IGF2R with Galpha proteins and its downstream PKA and PLC-beta modulators by IGF-II.

F. Tsai, Chih-Yang Huang, Chang-Hai Tsai, 2009, The Chinese journal of physiology.

IGF-II/mannose-6-phosphate receptor signaling induced cell hypertrophy and atrial natriuretic peptide/BNP expression via Galphaq interaction and protein kinase C-alpha/CaMKII activation in H9c2 cardiomyoblast cells.

F. Tsai, B. Tzang, W. Kuo, 2008, The Journal of endocrinology.

Immunoglobulin E and matrix metalloproteinase-9 in patients with different stages of coronary artery diseases.

F. Tsai, Shin-Da Lee, Dennis Jine-Yuan Hsieh, 2007, The Chinese journal of physiology.

Deep ocean minerals inhibit IL-6 and IGFIIR hypertrophic signalling pathways to attenuate diabetes-induced hypertrophy in rat hearts.

H. Ou, Dennis Jine-Yuan Hsieh, P. Pai, 2019, Journal of applied physiology.

Oral hydroxycitrate supplementation enhances glycogen synthesis in exercised human skeletal muscle

Shin-Da Lee, Chih-Yang Huang, Shih-Wei Huang, 2011, British Journal of Nutrition.

Association of genetic variants in senataxin and Alzheimer's disease in a Chinese Han population in Taiwan.

C. Tsai, Hsin-Ping Liu, Wei-Yong Lin, 2014, The Chinese journal of physiology.

Neferine, a bisbenzylisoquinoline alkaloid, offers protection against cobalt chloride-mediated hypoxia-induced oxidative stress in muscle cells

Chih-Yang Huang, V. V. Padma, P. Kalaiselvi, 2015, Integrative medicine research.

Resveratrol attenuated hydrogen peroxide-induced myocardial apoptosis by autophagic flux

Chih-Yang Huang, Wei-Jen Ting, Jing-yi Yang, 2016, Food & nutrition research.

Anti-Apoptotic Effects of Diosgenin in D-Galactose-Induced Aging Brain.

H. Ou, Shin-Da Lee, Chih-Yang Huang, 2020, The American journal of Chinese medicine.

Neferine ameliorates cardiomyoblast apoptosis induced by doxorubicin: possible role in modulating NADPH oxidase/ROS-mediated NFκB redox signaling cascade

Chih-Yang Huang, V. V. Padma, R. Baskaran, 2017, Scientific Reports.

Synthesis of phenolic amides and evaluation of their antioxidant and anti-inflammatory activity in vitro and in vivo

Chih-Yang Huang, You-Liang Hsieh, Y. Yeh, 2015 .

High-protein supplementation facilitates weight training-induced bone mineralization in baseball players.

Chih-Yang Huang, A. Alkhatib, Hui-Yu Huang, 2020, Nutrition.

Anti-apoptotic and pro-survival effects of exercise training on hypertensive hearts.

F. Tsai, Shin-Da Lee, Chih-Yang Huang, 2012, Journal of applied physiology.

Effects of β‐carotene on antioxidant status in rats with chronic alcohol consumption

Jiun-Rong Chen, Chih-Yang Huang, Chi-Chang Huang, 2009, Cell biochemistry and function.

Protective effects of Cholestin on ethanol induced oxidative stress in rats.

Chih-Yang Huang, You-Liang Hsieh, Y. Yeh, 2015, Journal of the science of food and agriculture.

Anti‐apoptotic effect of San Huang Shel Shin Tang cyclodextrin complex (SHSSTc) on CCl4‐induced hepatotoxicity in rats

Cheng-Hsun Yang, F. Tsai, Chih-Yang Huang, 2016, Environmental toxicology.

Mitochondrial co-chaperone protein Tid1 is required for energy homeostasis during skeletal myogenesis

Chih-Yang Huang, K. Hung, Li-Hao Cheng, 2016, Stem Cell Research & Therapy.

Probiotic-fermented purple sweet potato yogurt activates compensatory IGF‑IR/PI3K/Akt survival pathways and attenuates cardiac apoptosis in the hearts of spontaneously hypertensive rats.

F. Tsai, W. Kuo, Chih-Yang Huang, 2013, International journal of molecular medicine.

Cardiomyoblast apoptosis induced by insulin-like growth factor (IGF)-I resistance is IGF-II dependent and synergistically enhanced by angiotensin II

Chieh-Hsi Wu, Shin-Da Lee, W. Kuo, 2006, Apoptosis.

Anti-Apoptosis and Anti-Fibrosis Effects of Eriobotrya Japonica in Spontaneously Hypertensive Rat Hearts

V. Viswanadha, Chih-Yang Huang, Chia-Yao Shen, 2018, International journal of molecular sciences.

Platycodin D (PD) attenuates myocardial apoptosis mediated by JNK-SIRT1-HSF1-IGF-IIR-Caspase-3 signaling in hypertensive conditions

Yu Lin, W. Kuo, Tsung‐Jung Ho, 2017 .

Second-Hand Smoke–Induced Cardiac Fibrosis Is Related to the Fas Death Receptor Apoptotic Pathway without Mitochondria-Dependent Pathway Involvement in Rats

Chieh-Hsi Wu, Shin-Da Lee, W. Kuo, 2005, Environmental health perspectives.

ERβ targets ZAK and attenuates cellular hypertrophy via SUMO‐1 modification in H9c2 cells

W. Kuo, P. Pai, V. Viswanadha, 2018, Journal of cellular biochemistry.

Swimming exercise stimulates IGF1/ PI3K/Akt and AMPK/SIRT1/PGC1α survival signaling to suppress apoptosis and inflammation in aging hippocampus

W. Kuo, Tsung‐Jung Ho, Chih-Yang Huang, 2020, Aging.

Satellite cells depletion in exercising human skeletal muscle is restored by ginseng component Rg1 supplementation

Chih-Yang Huang, Jørgen Jensen, C. Kao, 2019, Journal of Functional Foods.

The soybean bioactive peptide VHVV alleviates hypertension-induced renal damage in hypertensive rats via the SIRT1-PGC1α/Nrf2 pathway

Ray-Jade Chen, W. Kuo, Dennis Jine-Yuan Hsieh, 2020 .

Palmitic acid interferes with energy metabolism balance by adversely switching the SIRT1-CD36-fatty acid pathway to the PKC zeta-GLUT4-glucose pathway in cardiomyoblasts.

Ray-Jade Chen, W. Kuo, Tsung‐Jung Ho, 2016, The Journal of nutritional biochemistry.

Rab9‐dependent autophagy is required for the IGF‐IIR triggering mitophagy to eliminate damaged mitochondria

S. Chiang, W. Kuo, P. Pai, 2018, Journal of cellular physiology.

New analytical method for investigating the antioxidant power of food extracts on the basis of their electron-donating ability: comparison to the ferric reducing/antioxidant power (FRAP) assay.

F. Tsai, Chih-Yang Huang, Hsi-Chin Wu, 2010, Journal of agricultural and food chemistry.

Anti-apoptotic effects of diosgenin on ovariectomized hearts

Shin-Da Lee, Chih-Yang Huang, M. Shibu, 2022, Steroids.

Bioactive peptides attenuate cardiac apoptosis in spontaneously hypertensive rat hearts through activation of autophagy and mitochondrial biogenesis pathway

Ray-Jade Chen, W. Kuo, Dennis Jine-Yuan Hsieh, 2020, Environmental toxicology.

Lactobacillus reuteri GMNL-263 reduces hyperlipidaemia and the heart failure process in high-calorie diet-fed induced heart dysfunction in rats

Ray-Jade Chen, W. Kuo, Chih-Yang Huang, 2016 .

Effect of superoxide anion scavenger on rat hearts with chronic intermittent hypoxia.

Shin-Da Lee, P. Pai, Chih-Yang Huang, 2016, Journal of applied physiology.

Effect of Superoxide Anion Scavenger on Rat Hearts with Chronic Intermittent 1 Hypoxia 2 3

Shin-Da Lee, P. Pai, Chih-Yang Huang, 2015 .

Protective effect of salidroside on cardiac apoptosis in mice with chronic intermittent hypoxia.

Shin-Da Lee, P. Pai, Chih-Yang Huang, 2014, International journal of cardiology.

Garlic oil attenuates the cardiac apoptosis in hamster-fed with hypercholesterol diet.

F. Tsai, Chih-Yang Huang, Tung-Sheng Chen, 2013, Food chemistry.

Suppression of TLR-4-related inflammatory pathway and anti-fibrosis effects of probiotic-fermented purple sweet potato yogurt in hearts of spontaneously hypertensive rats.

F. Tsai, W. Kuo, Chih-Yang Huang, 2013, The Chinese journal of physiology.

Effects of insulin replacement on cardiac apoptotic and survival pathways in streptozotocin‐induced diabetic rats

F. Tsai, Shin-Da Lee, W. Kuo, 2009, Cell biochemistry and function.

P38 mitogen‐activated protein kinase pathways are involved in the hypertrophy and apoptosis of cardiomyocytes induced by Porphyromonas gingivalis conditioned medium

Shin-Da Lee, W. Kuo, Dennis Jine-Yuan Hsieh, 2008, Cell biochemistry and function.

Short-term versus long-term intermittent hypobaric hypoxia on cardiac fibrosis and Fas death receptor dependent apoptotic pathway in rat hearts.

F. Tsai, Shin-Da Lee, Chih-Yang Huang, 2008, The Chinese journal of physiology.

Effects of long-term intermittent hypoxia on mitochondrial and Fas death receptor dependent apoptotic pathways in rat hearts.

Shin-Da Lee, W. Kuo, Chih-Yang Huang, 2007, International journal of cardiology.

Role of mitogen-activated protein kinase kinase in Porphyromonas gingivalis-induced myocardial cell hypertrophy and apoptosis.

Shin-Da Lee, W. Kuo, Chih-Yang Huang, 2006, European journal of oral sciences.

Porphyromonas gingivalis-related cardiac cell apoptosis was majorly co-activated by p38 and extracellular signal-regulated kinase pathways.

Shin-Da Lee, W. Kuo, Chih-Yang Huang, 2006, Journal of periodontal research.

Effects of short- and long-term hypobaric hypoxia on Bcl2 family in rat heart.

Chieh-Hsi Wu, Shin-Da Lee, W. Kuo, 2006, International journal of cardiology.

Role of calcineurin in Porphyromonas gingivalis-induced myocardial cell hypertrophy and apoptosis.

Shin-Da Lee, W. Kuo, Chih-Yang Huang, 2006, Journal of biomedical science.

Calycosin alleviates H2O2‐induced astrocyte injury by restricting oxidative stress through the Akt/Nrf2/HO‐1 signaling pathway

Ray-Jade Chen, W. Kuo, Tsung‐Jung Ho, 2022, Environmental toxicology.

Luteolin: A Natural Flavonoid Enhances the Survival of HUVECs against Oxidative Stress by Modulating AMPK/PKC Pathway.

H. Ou, W. Kuo, P. Pai, 2019, The American journal of Chinese medicine.

Oral Rg1 supplementation strengthens antioxidant defense system against exercise-induced oxidative stress in rat skeletal muscles

Mallikarjuna Korivi, Shin-Da Lee, Chih-Yang Huang, 2012, Journal of the International Society of Sports Nutrition.

Hypertrophy of cultured adult rat ventricular cardiomyocytes induced by antibodies against the insulin-like growth factor (IGF)-I or the IGF-I receptor is IGF-II-dependent

Chih-Yang Huang, D. E. Buetow, Ling-Yang Hao, 2002, Molecular and Cellular Biochemistry.

INSULIN‐LIKE GROWTH FACTOR‐II INDUCES HYPERTROPHY OF ADULT CARDIOMYOCYTES VIA TWO ALTERNATIVE PATHWAYS

Chih-Yang Huang, D. E. Buetow, Ling-Yang Hao, 2002, Cell biology international.

Pro‐inflammation and pro‐fibrosis factors were highly induction in heart tissues of carotid arteries balloon‐injured animal model

Chieh-Hsi Wu, F. Tsai, W. Kuo, 2012, Cell biochemistry and function.

Effect of dehydroepiandrosterone administration on recovery from mix-type exercise training-induced muscle damage

Shin-Da Lee, J. Ivy, Chih-Yang Huang, 2012, European Journal of Applied Physiology.

Altitude hypoxia increases glucose uptake in human heart.

Chi-Hsien Chen, Shin-Da Lee, Chih-Yang Huang, 2009, High altitude medicine & biology.

Tumorous imaginal disc 1 (TID1) inhibits isoproterenol-induced cardiac hypertrophy and apoptosis by regulating c-terminus of hsc70-interacting protein (CHIP) mediated degradation of Gαs

Ray-Jade Chen, L. Pan, Chih-Yang Huang, 2018, International journal of medical sciences.

EGCG protects against oxidized LDL-induced endothelial dysfunction by inhibiting LOX-1-mediated signaling.

Shun-Fa Yang, H. Ou, Kun-Ling Tsai, 2010, Journal of applied physiology.

17β-Estradiol and/or estrogen receptor alpha signaling blocks protein phosphatase 1 mediated ISO induced cardiac hypertrophy

W. Kuo, Kuan-Ho Lin, V. Viswanadha, 2018, PloS one.

ZAK induces cardiomyocyte hypertrophy and brain natriuretic peptide expression via p38/JNK signaling and GATA4/c-Jun transcriptional factor activation

P. Pai, V. Viswanadha, Chih-Yang Huang, 2015, Molecular and Cellular Biochemistry.

Danshen (Salvia miltiorhiza) inhibits Leu27 IGF‐II‐induced hypertrophy in H9c2 cells

W. Kuo, Tsung‐Jung Ho, Chih-Yang Huang, 2020, Environmental toxicology.

Secondhand Smoke Exposure Enhances Cardiac Fibrosis Effects on the Aging Rat Hearts.

W. Kuo, Tsung‐Jung Ho, V. Viswanadha, 2016, Acta Cardiologica Sinica.

Porphyromonas gingivalis-induced cellular hypertrophy and MMP-9 activity via different signaling pathways in H9c2 cardiomyoblast cells.

Chieh-Hsi Wu, Shin-Da Lee, W. Kuo, 2006, Journal of periodontology.

Protective effect of Co‐enzyme Q10 On doxorubicin‐induced cardiomyopathy of rat hearts

P. Pai, V. Viswanadha, Chih-Yang Huang, 2017, Environmental toxicology.

Bioactive flavone fisetin attenuates hypertension associated cardiac hypertrophy in H9c2 cells and in spontaneously hypertension rats

Ray-Jade Chen, W. Kuo, Kuan-Ho Lin, 2019, Journal of Functional Foods.

Tanshinone-induced ERs suppresses IGFII activation to alleviate Ang II-mediated cardiac hypertrophy

Ray-Jade Chen, W. Kuo, P. Pai, 2017, Journal of receptor and signal transduction research.

Mechanism of Taiwan Mingjian Oolong Tea to Inhibit Isoproterenol-Induced Hypertrophy and Apoptosis in Cardiomyoblasts.

Ray-Jade Chen, P. Pai, Tsung‐Jung Ho, 2016, The American journal of Chinese medicine.

Fasudil, a Rho-kinase inhibitor, protects against excessive endurance exercise training-induced cardiac hypertrophy, apoptosis and fibrosis in rats

Tsung‐Jung Ho, Chih-Yang Huang, Chi-Chang Huang, 2011, European Journal of Applied Physiology.

Bioactive peptides attenuate cardiac hypertrophy and fibrosis in spontaneously hypertensive rat hearts.

Chih-Yang Huang, Wan-Teng Lin, S. Nithiyanantham, 2020, Journal of food and drug analysis.

Effects of garlic oil on interleukin-6 mediated cardiac hypertrophy in hypercholesterol-fed hamsters.

Chieh-Hsi Wu, M. Fan, P. Pai, 2017, The Chinese journal of physiology.

Ameliorate Effects of Li-Fu Formula on IL-6-Mediated Cardiac Hypertrophy in Hamsters Fed with a Hyper-Cholesterol Diet

Chieh-Hsi Wu, F. Tsai, B. Tzang, 2011, Evidence-based complementary and alternative medicine : eCAM.

BNIP3 induces IL6 and calcineurin/NFAT3 hypertrophic-related pathways in H9c2 cardiomyoblast cells

F. Tsai, W. Kuo, Dennis Jine-Yuan Hsieh, 2010, Molecular and Cellular Biochemistry.

Eccentric cardiac hypertrophy was induced by long‐term intermittent hypoxia in rats

F. Tsai, Shin-Da Lee, W. Kuo, 2007, Experimental physiology.

Beneficial effects of taurine on cardiac abnormality in NZB/W F1 mice fed with a high-cholesterol diet.

B. Tzang, W. Kuo, Chih-Yang Huang, 2009, Journal of agricultural and food chemistry.

Adipose derived mesenchymal stem cells along with Alpinia oxyphylla extract alleviate mitochondria-mediated cardiac apoptosis in aging models and cardiac function in aging rats.

W. Kuo, Chih-Yang Huang, M. Shibu, 2020, Journal of ethnopharmacology.

Early Fluid Resuscitation by Lactated Ringer’s Solution Alleviate the Cardiac Apoptosis in Rats with Trauma-Hemorrhagic Shock

Wei-Kung Chen, W. Kuo, Kuan-Ho Lin, 2016, PloS one.

HSF1 phosphorylation by ERK/GSK3 suppresses RNF126 to sustain IGF‐IIR expression for hypertension‐induced cardiomyocyte hypertrophy

Ray-Jade Chen, W. Kuo, Kuan-Ho Lin, 2018, Journal of cellular physiology.

The p38 and NFκB signaling protein activation involved in glycitein protective effects on isoproterenol-treated H9c2 cardiomyoblast cells

F. Tsai, W. Kuo, Chih-Yang Huang, 2013 .

Genistein suppresses the isoproterenol-treated H9c2 cardiomyoblast cell apoptosis associated with P-38, Erk1/2, JNK, and NFκB signaling protein activation.

Ray-Jade Chen, F. Tsai, Tsung‐Jung Ho, 2013, The American journal of Chinese medicine.

Roles of insulin-like growth factor II in cardiomyoblast apoptosis and in hypertensive rat heart with abdominal aorta ligation.

Shin-Da Lee, W. Kuo, Chih-Yang Huang, 2006, American journal of physiology. Endocrinology and metabolism.

E4BP4 inhibits AngII‐induced apoptosis in H9c2 cardiomyoblasts by activating the PI3K‐Akt pathway and promoting calcium uptake

Ray-Jade Chen, Wei-Kung Chen, V. Viswanadha, 2018, Experimental cell research.

ZAK induces MMP-2 activity via JNK/p38 signals and reduces MMP-9 activity by increasing TIMP-1/2 expression in H9c2 cardiomyoblast cells

F. Tsai, W. Kuo, Chih-Yang Huang, 2009, Molecular and Cellular Biochemistry.

Impaired IGF‐I signalling of hypertrophic hearts in the developmental phase of hypertension in genetically hypertensive rats

Chieh-Hsi Wu, Shin-Da Lee, W. Kuo, 2005, Cell biochemistry and function.

Overexpression of IGF‐IIRα regulates cardiac remodeling and aggravates high salt induced apoptosis and fibrosis in transgenic rats

Ray-Jade Chen, W. Kuo, P. Pai, 2018, Environmental toxicology.

Protective Effects of Electroacupuncture at Lr3 on Cardiac Hypertrophy and Apoptosis in Hypertensive Rats

Dennis Jine-Yuan Hsieh, Tsung‐Jung Ho, V. Viswanadha, 2016, Acupuncture in medicine : journal of the British Medical Acupuncture Society.

IGF-II/mannose 6-phosphate receptor activation induces metalloproteinase-9 matrix activity and increases plasminogen activator expression in H9c2 cardiomyoblast cells.

Ray-Jade Chen, F. Tsai, W. Kuo, 2008, Journal of molecular endocrinology.

Mitochondrial ROS‐induced ERK1/2 activation and HSF2‐mediated AT1R upregulation are required for doxorubicin‐induced cardiotoxicity

W. Kuo, P. Pai, Tsung‐Jung Ho, 2018, Journal of cellular physiology.

Increased expression of glucose transporter 3 in gerbil brains following magnesium sulfate treatment and focal cerebral ischemic injury

F. Tsai, P. Pai, Chih-Yang Huang, 2010, Cell biochemistry and function.

Role of ERK signaling in the neuroprotective efficacy of magnesium sulfate treatment during focal cerebral ischemia in the gerbil cortex.

F. Tsai, Chih-Yang Huang, Wen-Yuan Lin, 2010, The Chinese journal of physiology.

Effects of estrogen on glutathione and catalase levels in human erythrocyte during menstrual cycle

Chih-Yang Huang, Jer‐Yuh Liu, Sheng-Huang Chang, 2015 .

Deep Ocean Minerals Minimize Eccentric Exercise-Induced Inflammatory Response of Rat Skeletal Muscle

Chih-Yang Huang, C. Kao, Rungchai Chuanchaiyakul, 2018, Front. Physiol..

Japanese Encephalitis Virus Envelope Protein Mitigates TNF-α mRNA Expression in RAW264.7 Cells

K. Lu, B. Tzang, Chih-Yang Huang, 2008, Inflammation.

Doxorubicin attenuates CHIP-guarded HSF1 nuclear translocation and protein stability to trigger IGF-IIR-dependent cardiomyocyte death

S. Chiang, W. Kuo, P. Pai, 2016, Cell Death & Disease.

Protective effects of galangin against H2O2/UVB-induced dermal fibroblast collagen degradation via hsa-microRNA-4535-mediated TGFβ/Smad signaling

W. Kuo, Chih-Yang Huang, V. V. Padma, 2021, Aging.

Novel target genes responsive to apoptotic activity by Ocimum gratissimum in human osteosarcoma cells.

Chih-Yang Huang, Chia-Yao Shen, Jer‐Yuh Liu, 2014, The American journal of Chinese medicine.

Ginsenoside Rg1 supplementation clears senescence-associated β-galactosidase in exercising human skeletal muscle

Chih-Yang Huang, Tiemin Liu, Shangyu Hong, 2018, Journal of ginseng research.

Homocysteine and other biochemical parameters in Type 2 diabetes mellitus with different diabetic duration or diabetic retinopathy.

B. Tzang, Shin-Da Lee, W. Kuo, 2006, Clinica chimica acta; international journal of clinical chemistry.

Beneficial effects of treatment with cystamine on brain in NZB/W F1 mice.

B. Tzang, Chih-Yang Huang, Yi‐Chen Chen, 2008, European journal of pharmacology.

Ramipril and resveratrol co‐treatment attenuates RhoA/ROCK pathway‐regulated early‐stage diabetic nephropathy‐associated glomerulosclerosis in streptozotocin‐induced diabetic rats

Chih-Yang Huang, Wei-Jen Ting, Xiang-Ping Peng, 2019, Environmental toxicology.

Protective effects of luteolin against oxidative stress and mitochondrial dysfunction in endothelial cells.

Hsiu-I. Chen, H. Ou, W. Kuo, 2020, Nutrition, metabolism, and cardiovascular diseases : NMCD.

Dehydroepiandrosterone sulfate linked to physiologic response against hot spring immersion

Shin-Da Lee, Chih-Yang Huang, C. Hsieh, 2009, Steroids.

Dietary oxidised frying oil causes oxidative damage of pancreatic islets and impairment of insulin secretion, effects associated with vitamin E deficiency.

Chih-Yang Huang, H. Shaw, P. Chao, 2011, The British journal of nutrition.

Inhibition of cell death-inducing p53 target 1 through miR-210-3p overexpression attenuates reactive oxygen species and apoptosis in rat adipose-derived stem cells challenged with Angiotensin II.

Ray-Jade Chen, W. Kuo, Dennis Jine-Yuan Hsieh, 2020, Biochemical and biophysical research communications.

E3 ligase activity of Carboxyl terminus of Hsc70 interacting protein (CHIP) in Wharton's jelly derived mesenchymal stem cells improves their persistence under hyperglycemic stress and promotes the prophylactic effects against diabetic cardiac damages

W. Kuo, Tsung‐Jung Ho, V. Viswanadha, 2021, Bioengineering & translational medicine.

Activation of snail and EMT-like signaling via the IKKαβ/NF-κB pathway in Apicidin-resistant HA22T hepatocellular carcinoma cells.

F. Tsai, Chih-Yang Huang, Ming-Cheng Chen, 2013, The Chinese journal of physiology.

miR-145-5p targets paxillin to attenuate angiotensin II-induced pathological cardiac hypertrophy via downregulation of Rac 1, pJNK, p-c-Jun, NFATc3, ANP and by Sirt-1 upregulation

Ray-Jade Chen, Kuan-Ho Lin, Tsung‐Jung Ho, 2021, Molecular and Cellular Biochemistry.

Anti-apoptotic and pro-survival effect of protocatechuic acid on hypertensive hearts.

M. Fan, F. Tsai, Shin-Da Lee, 2014, Chemico-biological interactions.

Nerolidol improves cardiac function in spontaneously hypertensive rats by inhibiting Cardiac Inflammation and remodelling associated TLR4/ NF-κB signalling cascade.

W. Kuo, Tsung‐Jung Ho, V. Viswanadha, 2020, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Change of serum growth factors in infants with isolated ventricular defect undergoing surgical repair.

Chih-Yang Huang, T. Tsai, Jung-Min Yu, 2002, The Annals of thoracic surgery.

Increased β-catenin accumulation and nuclear translocation are associated with concentric hypertrophy in cardiomyocytes.

Ray-Jade Chen, W. Kuo, P. Pai, 2017, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

Prolactin protects cardiomyocytes against intermittent hypoxia-induced cell damage by the modulation of signaling pathways related to cardiac hypertrophy and proliferation.

W. Kuo, Dennis Jine-Yuan Hsieh, P. Pai, 2015, International journal of cardiology.

β-catenin/LEF1/IGF-IIR Signaling Axis Galvanizes the Angiotensin-II- induced Cardiac Hypertrophy

Ray-Jade Chen, W. Kuo, P. Pai, 2019, International journal of molecular sciences.

Estrogen and/or Estrogen Receptor α Inhibits BNIP3-Induced Apoptosis and Autophagy in H9c2 Cardiomyoblast Cells

Hsin-Yueh Liang, V. Viswanadha, Chih-Yang Huang, 2018, International journal of molecular sciences.

IGF-IIRα is a novel stress-inducible contributor to cardiac damage underpinning doxorubicin-induced oxidative stress and perturbed mitochondrial autophagy.

Ray-Jade Chen, W. Kuo, P. Pai, 2019, American journal of physiology. Cell physiology.

Insulin-like growth factor II receptor- is a novel stress-inducible contributor to cardiac damage underpinning doxorubicin-induced oxidative stress and perturbed mitochondrial autophagy

Ray-Jade Chen, W. Kuo, P. Pai, 2019 .

Neferine modulates IGF‐1R/Nrf2 signaling in doxorubicin treated H9c2 cardiomyoblasts

Chih-Yang Huang, V. Vijaya Padma, R. Baskaran, 2018, Journal of cellular biochemistry.

Diallyl trisulfide protects against high glucose-induced cardiac apoptosis by stimulating the production of cystathionine gamma-lyase-derived hydrogen sulfide.

W. Kuo, Chih-Yang Huang, S. Wen, 2015, International journal of cardiology.

Oral administration of alcalase potato protein hydrolysate‐APPH attenuates high fat diet‐induced cardiac complications via TGF‐β/GSN axis in aging rats

V. Viswanadha, Chih-Yang Huang, Wei-Jen Ting, 2018, Environmental toxicology.

Protective effect of Danggui (Radix Angelicae Sinensis) on angiotensin II-induced apoptosis in H9c2 cardiomyoblast cells

F. Tsai, W. Kuo, Dennis Jine-Yuan Hsieh, 2014, BMC Complementary and Alternative Medicine.

Deep sea minerals ameliorate diabetic‐induced inflammation via inhibition of TNFα signaling pathways

Ray-Jade Chen, Hsiu-I. Chen, H. Ou, 2019, Environmental toxicology.

Outcomes of obese, clozapine-treated inpatients with schizophrenia placed on a six-month diet and physical activity program.

Ya-Mei Bai, Shin-Da Lee, Chih-Yang Huang, 2007, Psychiatric services.

Lactobacillus paracasei GMNL-32 exerts a therapeutic effect on cardiac abnormalities in NZB/W F1 mice

Ray-Jade Chen, B. Tzang, Tsung‐Jung Ho, 2017, PloS one.

Association of cyclooxygenase 2 single-nucleotide polymorphisms and hepatocellular carcinoma in Taiwan.

L. Jeng, Chih-Yang Huang, Wen-Shin Chang, 2012, The Chinese journal of physiology.

Apoptotic and anti-proliferative effects of 17β-estradiol and 17β-estradiol-like compounds in the Hep3B cell line

Shin-Da Lee, W. Kuo, Chih-Yang Huang, 2006, Molecular and Cellular Biochemistry.

Effects of oral Lactobacillus administration on antioxidant activities and CD4+CD25+forkhead box P3 (FoxP3)+ T cells in NZB/W F1 mice

B. Tzang, Chih-Yang Huang, T. Hsu, 2017, British Journal of Nutrition.

Perturbed ER homeostasis by IGF-IIRα promotes cardiac damage under stresses

Ray-Jade Chen, W. Kuo, P. Pai, 2021, Molecular and Cellular Biochemistry.

Fenofibrate induced PPAR alpha expression was attenuated by oestrogen receptor alpha overexpression in Hep3B cells

L. Jeng, Ray-Jade Chen, W. Kuo, 2018, Environmental toxicology.

Endothelin-1 enhances cell migration through COX-2 up-regulation in human chondrosarcoma.

M. Wu, F. Tsai, Chih-Yang Huang, 2013, Biochimica et biophysica acta.

SHSST Cyclodextrin Complex Prevents the Fibrosis Effect on CCl4-Induced Cirrhotic Cardiomyopathy in Rats through TGF-β Pathway Inhibition Effects

Cheng-Hsun Yang, Chih-Yang Huang, Wei-Jen Ting, 2014, International journal of molecular sciences.

Herbal supplement attenuation of cardiac fibrosis in rats with CCl₄-induced liver cirrhosis.

Ray-Jade Chen, F. Tsai, Chih-Yang Huang, 2014, The Chinese journal of physiology.

Herbal Supplement Ameliorates Cardiac Hypertrophy in Rats with CCl4-Induced Liver Cirrhosis

F. Tsai, P. Pai, Chih-Yang Huang, 2012, Evidence-Based Complementary and Alternative Medicine.

Augmented release of matrix metalloproteinase-9 by PKC activation in organotypic cultures of human breast cancer and adjacent normal breast tissue and fibroadenoma.

S. Kuo, Y. Hsieh, Chih-Yang Huang, 2004, The Chinese journal of physiology.

Chinese medicine acupoint herbal patching for allergic rhinitis: a randomized controlled clinical trial.

Chih-Yang Huang, Jaung-Geng Lin, N. Lai, 2010, The American journal of Chinese medicine.

Beneficial Effects of Treatment with Transglutaminase Inhibitor Cystamine on Macrophage Response in NZB/W F1 Mice

B. Tzang, Chih-Yang Huang, Chien-Ning Huang, 2007, Experimental biology and medicine.

Protein kinase C alpha location and the expression of phospho-MEK and MDR1 in hepatitis virus-related hepatocellular carcinoma biopsies.

Chih-Yang Huang, Li-mien Chen, T. Lai, 2010, The Chinese journal of physiology.

Neferine and isoliensinine enhance 'intracellular uptake of cisplatin' and induce 'ROS-mediated apoptosis' in colorectal cancer cells - A comparative study.

Chih-Yang Huang, Narasimha M. Beeraka, V. Vijaya Padma, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Aged cells in human skeletal muscle after resistance exercise

Chih-Yang Huang, J. Jensen, C. Kuo, 2018, Aging.

Calreticulin nuclear translocalization alleviates CaM/CaMKII/CREB signaling pathway to enhance chemosensitivity in HDAC inhibitor-resistant hepatocellular carcinoma cells

W. Kuo, Chih-Yang Huang, Ming-Cheng Chen, 2022, Aging.

The Root Extract of Gentiana macrophylla Pall. Alleviates Cardiac Apoptosis in Lupus Prone Mice

B. Tzang, Shin-Da Lee, W. Kuo, 2015, PloS one.

Carboxyl terminus of HSP70‐interacting protein attenuates advanced glycation end products‐induced cardiac injuries by promoting NFκB proteasomal degradation

W. Kuo, Kuan-Ho Lin, Chih-Yang Huang, 2021, Journal of cellular physiology.

Danshen mediates through estrogen receptors to activate Akt and inhibit apoptosis effect of Leu27IGF-II-induced IGF-II receptor signaling activation in cardiomyoblasts.

F. Tsai, B. Tzang, W. Kuo, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Treatment with taurine attenuates hepatic apoptosis in NZB/W F1 mice fed with a high-cholesterol diet.

B. Tzang, Chih-Yang Huang, Yi‐Chen Chen, 2008, Journal of agricultural and food chemistry.

Overexpression of ZAKβ in human osteosarcoma cells enhances ZAKα expression, resulting in a synergistic apoptotic effect

W. Kuo, V. Viswanadha, Chih-Yang Huang, 2018, Cell biochemistry and function.

RhoGDIβ-induced hypertrophic growth in H9c2 cells is negatively regulated by ZAK

Chih-Yang Huang, Kuan-Yu Liu, M. Chou, 2009, Journal of Biomedical Science.

PKCalpha expression regulated by Elk-1 and MZF-1 in human HCC cells.

Y. Hsieh, Chih-Yang Huang, Jer‐Yuh Liu, 2006, Biochemical and biophysical research communications.

Extracts of Jasminum sambac flowers fermented by Lactobacillus rhamnosus inhibit H2O2‐ and UVB‐induced aging in human dermal fibroblasts

W. Kuo, Chih-Yang Huang, S. Wen, 2020, Environmental toxicology.

Potato protein hydrolysate attenuates high fat diet-induced cardiac apoptosis through SIRT1/ PGC-1á/Akt signalling

P. Pai, Chih-Yang Huang, Wan-Teng Lin, 2015 .

Zanthoxylum avicennae extracts induce cell apoptosis through protein phosphatase 2A activation in HA22T human hepatocellular carcinoma cells and block tumor growth in xenografted nude mice.

F. Tsai, W. Kuo, Chih-Yang Huang, 2011, International journal of molecular medicine.

Secondhand Smoke Exposure Reduced the Compensatory Effects of IGF-I Growth Signaling in the Aging Rat Hearts

W. Kuo, Dennis Jine-Yuan Hsieh, P. Pai, 2015, International journal of medical sciences.

Zanthoxylum avicennae extract enhances GSK‐3β to attenuate β‐catenin via phosphatase 2A to block metastatic effects of HA22T cells and hepatocellular carcinoma xenografted nude mice

L. Jeng, Tsung‐Jung Ho, V. Viswanadha, 2017, Environmental toxicology.

Hormetic Property of Ginseng Steroids on Anti-Oxidant Status against Exercise Challenge in Rat Skeletal Muscle

Mallikarjuna Korivi, Shin-Da Lee, Chih-Yang Huang, 2017, Antioxidants.

Retinoic Acid Induces Apoptosis of Prostate Cancer DU145 Cells through Cdk5 Overactivation

S. Hsu, Chih-Yang Huang, Chuan‐Mu Chen, 2012, Evidence-based complementary and alternative medicine : eCAM.

Expression of protein kinase C alpha in biopsies and surgical specimens of human hepatocellular carcinoma.

Y. Hsieh, Chih-Yang Huang, K. Yeh, 2005, The Chinese journal of physiology.

Significant association of caveolin-1 genotypes with bladder cancer susceptibility in Taiwan.

S. Shyue, Chih-Yang Huang, C. Yao, 2011, The Chinese journal of physiology.

Expression of anti-cardiolipin antibodies and inflammatory associated factors in patients with schizophrenia

B. Tzang, Chih-Yang Huang, Chun-Ching Chiu, 2011, Psychiatry Research.

Oral administration of green tea Epigallocatechin-3-gallate reduces oxidative stress and enhances restoration of cardiac function in diabetic rats receiving autologous transplantation of adipose-derived stem cells

W. Kuo, Kuan-Ho Lin, Chih-Yang Huang, 2019, Archives of physiology and biochemistry.

Therapeutic effects of Dioscorea on post-menopause-induced cardiac apoptosis in rats

Shin-Da Lee, W. Kuo, V. Viswanadha, 2016, Chinese journal of integrative medicine.

Protocatechuic Acid from Alpinia oxyphylla Induces Schwann Cell Migration via ERK1/2, JNK and p38 Activation.

W. Kuo, Tsung‐Jung Ho, V. Viswanadha, 2015, The American journal of Chinese medicine.

Dilong: Role in Peripheral Nerve Regeneration

F. Tsai, W. Kuo, Chih-Yang Huang, 2011, Evidence-based complementary and alternative medicine : eCAM.

Schwann Cell Migration Induced by Earthworm Extract via Activation of PAs and MMP2/9 Mediated through ERK1/2 and p38

F. Tsai, W. Kuo, Chih-Yang Huang, 2011, Evidence-based complementary and alternative medicine : eCAM.

Rhubarb inhibits hepatocellular carcinoma cell metastasis via GSK-3-β activation to enhance protein degradation and attenuate nuclear translocation of β-catenin.

F. Tsai, Chih-Yang Huang, Wei-Jen Ting, 2013, Food chemistry.

Leu27IGF‐II‐induced hypertrophy in H9c2 cardiomyoblasts is ameliorated by saffron by regulation of calcineurin/NFAT and CaMKIIδ signaling

Ray-Jade Chen, W. Kuo, Tsung‐Jung Ho, 2021, Environmental toxicology.

The combined inhibition of the CaMKIIδ and calcineurin signaling cascade attenuates IGF‐IIR‐induced cardiac hypertrophy

W. Kuo, Tsung‐Jung Ho, Chih-Yang Huang, 2020, Journal of cellular physiology.

Secondhand smoke exposure toxicity accelerates age-related cardiac disease in old hamsters

W. Kuo, Tsung‐Jung Ho, Chih-Yang Huang, 2014, BMC Cardiovascular Disorders.

Dung-Shen Downregulates the Synergistic Apoptotic Effects of Angiotensin II Plus Leu 27-IGF II on Cardiomyoblasts.

F. Tsai, W. Kuo, Chih-Yang Huang, 2014, Acta Cardiologica Sinica.

Dung-shen (Codonopsis pilosula) attenuated the cardiac-impaired insulin-like growth factor II receptor pathway on myocardial cells.

F. Tsai, B. Tzang, Chih-Yang Huang, 2013, Food chemistry.

Inhibition of cardiac hypertrophy by probiotic-fermented purple sweet potato yogurt in spontaneously hypertensive rat hearts.

F. Tsai, W. Kuo, Chih-Yang Huang, 2012, International journal of molecular medicine.

Carthamus tinctorius L. extract activates insulin‐like growth factor‐I receptor signaling to inhibit FAS‐death receptor pathway and suppress lipopolysaccharides‐induced H9c2 cardiomyoblast cell apoptosis

Dennis Jine-Yuan Hsieh, Chih-Yang Huang, T. D. Dung, 2019, Environmental toxicology.

Nrf2 Activation as a Protective Feedback to Limit Cell Death in High Glucose‐Exposed Cardiomyocytes

W. Kuo, V. Viswanadha, Chih-Yang Huang, 2017, Journal of cellular biochemistry.

Induction of Autophagy by Vasicinone Protects Neural Cells from Mitochondrial Dysfunction and Attenuates Paraquat-Mediated Parkinson’s Disease Associated α-Synuclein Levels

Ray-Jade Chen, W. Kuo, Tsung‐Jung Ho, 2020, Nutrients.

Cardioprotective potential of amygdalin against angiotensin II induced cardiac hypertrophy, oxidative stress and inflammatory responses through modulation of Nrf2 and NF‐κB activation

Ray-Jade Chen, W. Kuo, Chih-Yang Huang, 2021, Environmental toxicology.

Deep Ocean Mineral Supplementation Enhances the Cerebral Hemodynamic Response during Exercise and Decreases Inflammation Postexercise in Men at Two Age Levels

Chih-Yang Huang, R. Chaunchaiyakul, Yung-Shen Tsai, 2017, Frontiers in Physiology.

Cytoprotective Effect of American Ginseng in a Rat Ethanol Gastric Ulcer Model

Chih-Yang Huang, M. Hsu, C. Chiu, 2013, Molecules.

Ginsenoside-Rg1 Protects the Liver against Exhaustive Exercise-Induced Oxidative Stress in Rats

Mallikarjuna Korivi, Shin-Da Lee, Chih-Yang Huang, 2011, Evidence-based complementary and alternative medicine : eCAM.

Proliferative effects of chishao on injured peripheral neurons.

F. Tsai, Chih-Yang Huang, Chang-Hai Tsai, 2010, The American journal of Chinese medicine.

Dangshen (Codonopsis pilosula) activates IGF-I and FGF-2 pathways to induce proliferation and migration effects in RSC96 Schwann cells.

F. Tsai, B. Tzang, Chih-Yang Huang, 2010, The American journal of Chinese medicine.

Proliferation‐ and migration‐enhancing effects of ginseng and ginsenoside Rg1 through IGF‐I‐ and FGF‐2‐signaling pathways on RSC96 Schwann cells

F. Tsai, W. Kuo, Chih-Yang Huang, 2009, Cell biochemistry and function.

The proliferation and migration effects of huangqi on RSC96 Schwann cells.

F. Tsai, W. Kuo, Chih-Yang Huang, 2009, The American journal of Chinese medicine.

Proliferative effects of Chishao on Schwann cells are FGF-uPA, and ERK- and JNK-dependent.

F. Tsai, H. Ou, W. Kuo, 2009, The American journal of Chinese medicine.

p53-mediated miR-18 repression activates HSF2 for IGF-IIR-dependent myocyte hypertrophy in hypertension-induced heart failure

W. Kuo, P. Pai, Tsung‐Jung Ho, 2017, Cell Death & Disease.

Cardioprotective effects of transplanted adipose‐derived stem cells under Ang II stress with Danggui administration augments cardiac function through upregulation of insulin‐like growth factor 1 receptor in late‐stage hypertension rats

Ray-Jade Chen, W. Kuo, Dennis Jine-Yuan Hsieh, 2021, Environmental toxicology.

Short‐term hypoxia upregulated Mas receptor expression to repress the AT1R signaling pathway and attenuate Ang II‐induced cardiomyocyte apoptosis

Tsung‐Jung Ho, V. Viswanadha, Chih-Yang Huang, 2018, Journal of cellular biochemistry.

Impact of LPS-Induced Cardiomyoblast Cell Apoptosis Inhibited by Earthworm Extracts

W. Kuo, P. Pai, Chih-Yang Huang, 2014, Cardiovascular Toxicology.

Anti‐apoptotic and pro‐survival effects of longan flower extracts on rat hearts with fructose‐induced metabolic syndrome

Shin-Da Lee, Chih-Yang Huang, Liang-Yi Wu, 2021, Environmental toxicology.

Arecoline induces cardiotoxicity by upregulating and activating cardiac hypertrophy-related pathways in Sprague-Dawley rats.

Ray-Jade Chen, W. Kuo, Tsung‐Jung Ho, 2022, Chemico-biological interactions.

Neferine attenuates doxorubicin‐induced fibrosis and hypertrophy in H9c2 cells

V. Viswanadha, Chih-Yang Huang, Baskaran Rathinasamy, 2022, Journal of biochemical and molecular toxicology.

Platycodin D reverses histone deacetylase inhibitor resistance in hepatocellular carcinoma cells by repressing ERK1/2-mediated cofilin-1 phosphorylation.

Ray-Jade Chen, Chih-Yang Huang, Ming-Cheng Chen, 2020, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Hsa-miR-107 regulates chemosensitivity and inhibits tumor growth in hepatocellular carcinoma cells

Chih-Yang Huang, Ming-Cheng Chen, Tso-fu Wang, 2021, Aging.

Improved Inflammatory Balance of Human Skeletal Muscle during Exercise after Supplementations of the Ginseng-Based Steroid Rg1

Shin-Da Lee, J. Ivy, Chih-Yang Huang, 2015, PloS one.

Short‐Term Hypoxia Reverses Ox‐LDL‐Induced CD36 and GLUT4 Switching Metabolic Pathways in H9c2 Cardiomyoblast Cells

W. Kuo, Tsung‐Jung Ho, Chih-Yang Huang, 2017, Journal of cellular biochemistry.

Exercise training augments Sirt1-signaling and attenuates cardiac inflammation in D-galactose induced-aging rats

Ray-Jade Chen, Wei-Kung Chen, W. Kuo, 2018, Aging.

Hyperglycemia and advanced glycation end products (AGEs) suppress the differentiation of 3T3-L1 preadipocytes.

Chih-Yang Huang, G. Chang, Chung‐ho Chang, 2017, Oncotarget.

IGF IIRα-triggered pathological manifestations in the heart aggravate renal inflammation in STZ-induced type-I diabetes rats

Yung-Hsien Chang, Tsung‐Jung Ho, V. Viswanadha, 2021, Aging.

Reduction of TLR4 mRNA stability and protein expressions through inhibiting cytoplasmic translocation of HuR transcription factor by E₂ and/or ERα in LPS-treated H9c2 cardiomyoblast cells.

M. Fan, F. Tsai, P. Pai, 2014, The Chinese journal of physiology.

Edible folic acid and medicinal folinic acid produce cardioprotective effects in late‐stage triple‐transgenic Alzheimer's disease model mice by suppressing cardiac hypertrophy and fibrosis

Ray-Jade Chen, Tsung‐Jung Ho, Chih-Yang Huang, 2022, Environmental toxicology.

Galangin suppresses H2O2‐induced aging in human dermal fibroblasts

W. Kuo, Chih-Yang Huang, S. Wen, 2017, Environmental toxicology.

IGF-II and MMP9 as surgical repair indicators of ventricular septal defects.

F. Tsai, Dennis Jine-Yuan Hsieh, Chih-Yang Huang, 2011, Clinica chimica acta; international journal of clinical chemistry.

Pkcδ Activation is Involved in ROS-Mediated Mitochondrial Dysfunction and Apoptosis in Cardiomyocytes Exposed to Advanced Glycation End Products (Ages)

W. Kuo, Chih-Yang Huang, R. Aneja, 2018, Aging and disease.

Activation of IGF-I Survival Signaling and Its Compensative Inhibition of the Cardiac Apoptosis on Carotid Arteries Balloon-Injured Rat Hearts.

Chieh-Hsi Wu, P. Pai, Tsung‐Jung Ho, 2017, The Chinese journal of physiology.

GABA tea ameliorates cerebral cortex apoptosis and autophagy in streptozotocin-induced diabetic rats

W. Kuo, Chih-Yang Huang, Yueh-min Lin, 2014 .

CHIP Reverses Hyperglycemia-associated PTEN Stability in Wharton's Jelly Derived Mesenchymal Stem Cells and Promotes Its Therapeutic Potential Against Diabetes-induced Cardiac Injury

Ray-Jade Chen, W. Kuo, Tsung‐Jung Ho, 2021 .

Neuron Regeneration and Proliferation Effects of Danshen and Tanshinone IIA

F. Tsai, M. Chou, B. Tzang, 2010, Evidence-based complementary and alternative medicine : eCAM.

Prolactin secretion and intracellular Ca2+ change in rat lactotroph subpopulations stimulated by thyrotropin‐releasing hormone

Y. Hsieh, W. Kuo, Chih-Yang Huang, 2002, Journal of cellular biochemistry.

Functional potato bioactive peptide intensifies Nrf2-dependent antioxidant defense against renal damage in hypertensive rats.

Dennis Jine-Yuan Hsieh, Tsung‐Jung Ho, V. Viswanadha, 2020, Food research international.

Effect of taurine in chronic alcoholic patients.

Chih-Yang Huang, You-Liang Hsieh, Y. Yeh, 2014, Food & function.

Crude extracts of Solanum lyratum protect endothelial cells against oxidized low-density lipoprotein-induced injury by direct antioxidant action.

Jing-Gung Chung, Shun-Fa Yang, H. Ou, 2009, Journal of vascular surgery.

Elevated Phosphate Levels Trigger Autophagy-Mediated Cellular Apoptosis in H9c2 Cardiomyoblasts

Ray-Jade Chen, Wei-Kung Chen, Kuan-Ho Lin, 2017, Cardiorenal Medicine.

Bioactive Peptide Improves Diet-Induced Hepatic Fat Deposition and Hepatocyte Proinflammatory Response in SAMP8 Ageing Mice

W. Kuo, V. Viswanadha, Chih-Yang Huang, 2018, Cellular Physiology and Biochemistry.

Synergistic effect of HIF‐1α and FoxO3a trigger cardiomyocyte apoptosis under hyperglycemic ischemia condition

Ray-Jade Chen, W. Kuo, Tsung‐Jung Ho, 2018, Journal of cellular physiology.

Role of potato protein hydrolysate and exercise in preventing high-fat diet-induced hepatocyte apoptosis in senescence-accelerated mouse.

Ray-Jade Chen, W. Kuo, Tsung‐Jung Ho, 2020, Journal of food biochemistry.

ROS‐ and HIF1α‐dependent IGFBP3 upregulation blocks IGF1 survival signaling and thereby mediates high‐glucose‐induced cardiomyocyte apoptosis

W. Kuo, Chih-Yang Huang, S. Wen, 2019, Journal of cellular physiology.

Heat-Killed Lactobacillus reuteri GMNL-263 Inhibits Systemic Lupus Erythematosus–Induced Cardiomyopathy in NZB/W F1 Mice

B. Tzang, W. Kuo, Chih-Yang Huang, 2020, Probiotics and Antimicrobial Proteins.

Heat Killed Lactobacillus reuteri GMNL-263 Reduces Fibrosis Effects on the Liver and Heart in High Fat Diet-Hamsters via TGF-β Suppression

Ray-Jade Chen, W. Kuo, Dennis Jine-Yuan Hsieh, 2015, International journal of molecular sciences.

Secondhand smoke induces hepatic apoptosis and fibrosis in hamster fetus

B. Tzang, Chih-Yang Huang, C. Horng, 2016, Human & experimental toxicology.

Novel Herbal Formulation Jing Si Exhibits Multiple Functions to Inhibit Replication Activity and Subsides Viral Load of COVID-19 Variants

W. Kuo, Tsung‐Jung Ho, Chih-Yang Huang, 2022 .

Suppression of isoproterenol-induced apoptosis in H9c2 cardiomyoblast cells by daidzein through activation of Akt.

Ray-Jade Chen, W. Kuo, L. Pan, 2016, The Chinese journal of physiology.

Poria cocos (Fuling) targets TGFβ/Smad7 associated collagen accumulation and enhances Nrf2‐antioxidant mechanism to exert anti‐skin aging effects in human dermal fibroblasts

W. Kuo, Dennis Jine-Yuan Hsieh, Tsung‐Jung Ho, 2020, Environmental toxicology.

Lipolysis stimulating peptides of potato protein hydrolysate effectively suppresses high-fat-diet-induced hepatocyte apoptosis and fibrosis in aging rats

Chih-Yang Huang, Wan-Teng Lin, Wen-Dee Chiang, 2016, Food & nutrition research.

Lipolysis-stimulating peptide-VHVV ameliorates high fat diet induced hepatocyte apoptosis and fibrosis

F. Tsai, L. Pan, Chih-Yang Huang, 2014 .

Attenuation of Oxidative Stress-Induced Cell Apoptosis in Schwann RSC96 Cells by Ocimum Gratissimum Aqueous Extract

Chih-Yang Huang, Wei-Jen Ting, Jer‐Yuh Liu, 2017, International journal of medical sciences.

NFIL3 Suppresses Hypoxia‐induced Apoptotic Cell Death by Targeting the Insulin‐like Growth Factor 2 Receptor

Wei-Kung Chen, W. Kuo, P. Pai, 2015, Journal of cellular biochemistry.

Bioactive Peptide VHVV Upregulates the Long-Term Memory-Related Biomarkers in Adult Spontaneously Hypertensive Rats

W. Kuo, Tsung‐Jung Ho, V. Viswanadha, 2019, International journal of molecular sciences.

Pathological and biochemical analysis of dilated cardiomyopathy of broiler chickens--an animal model.

Chih-Yang Huang, C. Shyu, K. Ueng, 2003, The Chinese journal of physiology.

Fisetin activates Hippo pathway and JNK/ERK/AP‐1 signaling to inhibit proliferation and induce apoptosis of human osteosarcoma cells via ZAK overexpression

V. Viswanadha, Chih-Yang Huang, Ming-Cheng Chen, 2019, Environmental toxicology.

Enhancement of beta-catenin in cardiomyocytes suppresses survival protein expression but promotes apoptosis and fibrosis.

Ray-Jade Chen, W. Kuo, Tsung‐Jung Ho, 2017, Cardiology journal.

Taiwanin E inhibits cell migration in human LoVo colon cancer cells by suppressing MMP‐2/9 expression via p38 MAPK pathway

Ray-Jade Chen, Y. Kuo, W. Kuo, 2017, Environmental toxicology.

Protective effects of L-arginine supplementation against exhaustive exercise-induced oxidative stress in young rat tissues.

Chih-Yang Huang, Chi-Chang Huang, Wan-Teng Lin, 2009, The Chinese journal of physiology.

Daidzein Synergizes with Gefitinib to Induce ROS/JNK/c-Jun Activation and Inhibit EGFR-STAT/AKT/ERK Pathways to enhance Lung Adenocarcinoma cells chemosensitivity

T. Shih, Ray-Jade Chen, W. Kuo, 2022, International journal of biological sciences.

RSC96 Schwann Cell Proliferation and Survival Induced by Dilong through PI3K/Akt Signaling Mediated by IGF-I

F. Tsai, W. Kuo, Chih-Yang Huang, 2011, Evidence-based complementary and alternative medicine : eCAM.

Effect of oral administration of Pheretima aspergillum (earthworm) in rats with cerebral infarction induced by middle-cerebral artery occlusion.

Chih-Yang Huang, C. Hsieh, Yi-Wen Lin, 2012, African journal of traditional, complementary, and alternative medicines : AJTCAM.

Soya-cerebroside reduces IL-1β-induced MMP-1 production in chondrocytes and inhibits cartilage degradation: implications for the treatment of osteoarthritis

Jai-Sing Yang, Jing-Gung Chung, F. Tsai, 2019, Food and Agricultural Immunology.

Deep ocean mineral water accelerates recovery from physical fatigue

J. Ivy, Chih-Yang Huang, Yung-Shen Tsai, 2013, Journal of the International Society of Sports Nutrition.

Acute Low-level Chronic Cigarette Smoke Exposure is always Harmful to Left Ventricular Function in older Rats.

Chih-Yang Huang, Jia-Ping Wu, 2014 .

SENP1 participates in Irinotecan resistance in human colon cancer cells

Tsung‐Jung Ho, Chih-Yang Huang, Ming-Cheng Chen, 2021, Journal of cellular biochemistry.

Low‐dose rapamycin prevents Ang‐II‐induced toxicity in Leydig cells and testicular dysfunction in hypertensive SHR model

Ray-Jade Chen, W. Kuo, Tsung‐Jung Ho, 2022, Journal of biochemical and molecular toxicology.

Traditional Chinese medicine formula T33 inhibits the proliferation of human colorectal cancer cells by inducing autophagy

B. Tzang, Chih-Yang Huang, Yi-Hsuan Chiang, 2022, Environmental toxicology.

Pheretima aspergillum extract attenuates high‐KCl‐induced mitochondrial injury and pro‐fibrotic events in cardiomyoblast cells

V. Viswanadha, Chih-Yang Huang, M. Shibu, 2019, Environmental toxicology.

HSP40 co-chaperone protein Tid1 suppresses metastasis of head and neck cancer by inhibiting Galectin-7-TCF3-MMP9 axis signaling

Chih-Yang Huang, Yi-Chen Wu, Te-Chang Lee, 2018, Theranostics.

Earthworms Dilong: Ancient, Inexpensive, Noncontroversial Models May Help Clarify Approaches to Integrated Medicine Emphasizing Neuroimmune Systems

M. Paoletti, Chih-Yang Huang, E. Cooper, 2012, Evidence-based complementary and alternative medicine : eCAM.

Beneficial Effects of Ocimum gratissimum Aqueous Extract on Rats with CCl4-Induced Acute Liver Injury

B. Tzang, Chih-Yang Huang, Jer‐Yuh Liu, 2012, Evidence-based complementary and alternative medicine : eCAM.

Dietary potato peel extract reduces the toxicity of cholesterol oxidation products in rats

Chih-Yang Huang, You-Liang Hsieh, Y. Yeh, 2016 .

Inhibitory effects of isoliquiritigenin on the migration and invasion of human breast cancer cells

F. Chang, Chih-Yang Huang, Kai-Lee Wang, 2013, Expert opinion on therapeutic targets.

Cryptotanshinone (Dsh‐003) from Salvia miltiorrhiza Bunge inhibits prostaglandin E2‐induced survival and invasion effects in HA22T hepatocellular carcinoma cells

V. Viswanadha, Chih-Yang Huang, M. Shibu, 2018, Environmental toxicology.

Effect of Vasicinone against Paraquat-Induced MAPK/p53-Mediated Apoptosis via the IGF-1R/PI3K/AKT Pathway in a Parkinson’s Disease-Associated SH-SY5Y Cell Model

W. Kuo, Tsung‐Jung Ho, V. Viswanadha, 2019, Nutrients.

Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ERα Inhibition

Chih-Yang Huang, Ho Lin, Mei-Chih Chen, 2013, Evidence-based complementary and alternative medicine : eCAM.

Signal transducer and activator of transcription 3 mediates apoptosis inhibition through reducing mitochondrial ROS and activating Bcl‐2 in gemcitabine‐resistant lung cancer A549 cells

W. Kuo, Chih-Yang Huang, S. Wen, 2020, Journal of cellular physiology.

Neferine prevents NF-κB translocation and protects muscle cells from oxidative stress and apoptosis induced by hypoxia.

P. Poornima, Chih-Yang Huang, V. V. Padma, 2016, BioFactors.

Ellagic acid protects endothelial cells from oxidized low-density lipoprotein-induced apoptosis by modulating the PI3K/Akt/eNOS pathway.

W. Sheu, H. Ou, Kun-Ling Tsai, 2010, Toxicology and applied pharmacology.

Calmodulin/CaMKII‐γ mediates prosurvival capability in apicidin‐persistent hepatocellular carcinoma cells via ERK1/2/CREB/c‐fos signaling pathway

W. Kuo, Chih-Yang Huang, Ming-Cheng Chen, 2021, Journal of cellular biochemistry.

Seven traditional Chinese herbal extracts fermented by Lactobacillus rhamnosus provide anti‐pigmentation effects by regulating the CREB/MITF/tyrosinase pathway

W. Kuo, Chih-Yang Huang, S. Wen, 2020, Environmental toxicology.

The application of (-)-epigallocatechin gallate in preparation of an antioxidant dialysate.

F. Tsai, Chih-Yang Huang, Hsi-Chin Wu, 2012, Food chemistry.

Inhibitory effects of Physalis angulata on tumor metastasis and angiogenesis.

Jing-Gung Chung, Hsueh-Wei Chang, Chun-Yin Huang, 2011, Journal of ethnopharmacology.

An updated review on pharmacological properties of neferine-A bisbenzylisoquinoline alkaloid from Nelumbo nucifera.

Chih-Yang Huang, B. Balasubramanian, R. Baskaran, 2021, Journal of food biochemistry.

Inhibition of lipopolysaccharide-induced interleukin-1β and tumor necrosis factor-α production by menthone through nuclear factor-κB signaling pathway in HaCat cells

Chih-Yang Huang, D. Bau, Guang-wei Chen, 2008 .

Neferine suppresses diethylnitrosamine-induced lung carcinogenesis in Wistar rats.

V. Viswanadha, Chih-Yang Huang, V. Amirthalingam, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Tanshinone IIA Prevents Leu27IGF-II-Induced Cardiomyocyte Hypertrophy Mediated by Estrogen Receptor and Subsequent Akt Activation.

W. Kuo, Dennis Jine-Yuan Hsieh, P. Pai, 2015, The American journal of Chinese medicine.

Earthworm extracts facilitate PC12 cell differentiation and promote axonal sprouting in peripheral nerve injury.

T. Lu, F. Tsai, Chih-Yang Huang, 2010, The American journal of Chinese medicine.

Alpinia oxyphylla Miq. fruit extract activates IGFR-PI3K/Akt signaling to induce Schwann cell proliferation and sciatic nerve regeneration

Ray-Jade Chen, Tsung‐Jung Ho, Chih-Yang Huang, 2017, BMC Complementary and Alternative Medicine.

A review on the effects of current chemotherapy drugs and natural agents in treating non–small cell lung cancer

Chih-Yang Huang, D. Ju, B. Velmurugan, 2017, BioMedicine.

Asymmetric chitosan membrane containing collagen I nanospheres for skin tissue engineering.

Chun-Hsu Yao, Fuu-Jen Tsai, Kuo-Yu Chen, 2009, Biomacromolecules.

Textile fabricated biodegradable composite stents with core-shell structure

Chih-Yang Huang, Yueh-Sheng Chen, Mei-Chen Lin, 2020 .

Biocompatibility and Favorable Response of Mesenchymal Stem Cells on Fibronectin-Gold Nanocomposites

S. Hsu, Chih-Yang Huang, Shinn-Zong Lin, 2013, PloS one.

Fraxinus rhynchophylla ethanol extract attenuates carbon tetrachloride-induced liver fibrosis in rats via down-regulating the expressions of uPA, MMP-2, MMP-9 and TIMP-1.

Chao‐Lin Kuo, Chih-Yang Huang, Jung-Chun Liao, 2010, Journal of ethnopharmacology.

Glucocerebroside reduces endothelial progenitor cell-induced angiogenesis

Jai-Sing Yang, Jing-Gung Chung, F. Tsai, 2019, Food and Agricultural Immunology.

Mushrooms: A Wealth of Resource for Prospective Stem Cell-Based Therapies

D. Agrawal, Chih-Yang Huang, M. Shibu, 2019, Medicinal Mushrooms.

Purple rice anthocyanin extract protects cardiac function in STZ-induced diabetes rat hearts by inhibiting cardiac hypertrophy and fibrosis.

M. Fan, W. Kuo, Kuan-Ho Lin, 2016, The Journal of nutritional biochemistry.

Tetramethylpyrazine reverses high-glucose induced hypoxic effects by negatively regulating HIF-1α induced BNIP3 expression to ameliorate H9c2 cardiomyoblast apoptosis

Jai-Sing Yang, Jing-Gung Chung, F. Tsai, 2020, Nutrition & Metabolism.

Aqueous extract of Solanum nigrum attenuates Angiotensin-II induced cardiac hypertrophy and improves cardiac function by repressing protein kinase C-ζ to restore HSF2 deSUMOlyation and Mel-18-IGF-IIR signaling suppression.

Ray-Jade Chen, W. Kuo, Chih-Yang Huang, 2021, Journal of ethnopharmacology.

Plumbagin suppresses endothelial progenitor cell-related angiogenesis in vitro and in vivo

Jai-Sing Yang, Jing-Gung Chung, F. Tsai, 2019, Journal of Functional Foods.

Apicidin-resistant HA22T hepatocellular carcinoma cells massively promote pro-survival capability via IGF-IR/PI3K/Akt signaling pathway activation

F. Tsai, W. Kuo, Tsung‐Jung Ho, 2013, Tumor Biology.

Association of XRCC4 codon 247 polymorphism with oral cancer susceptibility in Taiwan.

M. Tsai, Chih-Yang Huang, D. Bau, 2008, Anticancer research.

Inhibition of Cardiac Hypertrophy Effects in D-Galactose-Induced Senescent Hearts by Alpinate Oxyphyllae Fructus Treatment

Ray-Jade Chen, Hsin-Nung Chang, Chih-Yang Huang, 2017, Evidence-based complementary and alternative medicine : eCAM.

Ganoderma microsporum immunomodulatory protein, GMI, promotes C2C12 myoblast differentiation in vitro via upregulation of Tid1 and STAT3 acetylation

Chih-Yang Huang, W. Teo, Jeng-Fan Lo, 2020, PloS one.

17beta-estradiol reduces cardiac hypertrophy mediated through the up-regulation of PI3K/Akt and the suppression of calcineurin/NF-AT3 signaling pathways in rats.

Chieh-Hsi Wu, Shin-Da Lee, W. Kuo, 2005, Life sciences.

The epithelial-mesenchymal transition mediator S100A4 maintains cancer-initiating cells in head and neck cancers.

Yau-Hua Yu, S. Chiou, Chih-Yang Huang, 2011, Cancer research.

PP2A mediates diosmin p53 activation to block HA22T cell proliferation and tumor growth in xenografted nude mice through PI3K-Akt-MDM2 signaling suppression.

F. Tsai, W. Kuo, Chih-Yang Huang, 2012, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

p38α MAPK mediates 17β‐estradiol inhibition of MMP‐2 and ‐9 expression and cell migration in human lovo colon cancer cells

Ray-Jade Chen, F. Tsai, Chih-Yang Huang, 2012, Journal of cellular physiology.

Lactobacillus paracasei GMNL-32, Lactobacillus reuteri GMNL-89 and L. reuteri GMNL-263 ameliorate hepatic injuries in lupus-prone mice

B. Tzang, Chih-Yang Huang, T. Hsu, 2017, British Journal of Nutrition.

Mesenchymal Stem Cell Insights: Prospects in Cardiovascular Therapy

F. Tsai, W. Kuo, P. Pai, 2014, Cell transplantation.

Downregulated CXCL12 expression in mesenchymal stem cells associated with severe aplastic anemia in children

S. Chiang, Chih-Yang Huang, K. Chow, 2014, Annals of Hematology.

Overexpression of protein kinase C alpha mRNA in human hepatocellular carcinoma: a potential marker of disease prognosis.

Y. Hsieh, Chih-Yang Huang, Jer‐Yuh Liu, 2007, Clinica chimica acta; international journal of clinical chemistry.

Cytotoxic effect of s-petasin and iso-s-petasin on the proliferation of human prostate cancer cells.

Chih-Yang Huang, D. Bau, J. Chou, 2015, Anticancer research.

Cantharidin decreased viable cell number in human osteosarcoma U-2 OS cells through G2/M phase arrest and induction of cell apoptosis

Jai-Sing Yang, Jing-Gung Chung, F. Tsai, 2019, Bioscience, biotechnology, and biochemistry.

Mitochondrial protein ATPase family, AAA domain containing 3A correlates with radioresistance in glioblastoma.

S. Chiang, Chih-Yang Huang, Tzei-Yi Lin, 2013, Neuro-oncology.

Baicalein inhibits the migration and invasive properties of human hepatoma cells.

Chih-Yang Huang, H. Kuo, Wu-Hsien Kuo, 2011, Toxicology and applied pharmacology.

Over-expressed estrogen receptor-α up-regulates hTNF-α gene expression and down-regulates β-catenin signaling activity to induce the apoptosis and inhibit proliferation of LoVo colon cancer cells

Shin-Da Lee, W. Kuo, Chih-Yang Huang, 2006, Molecular and Cellular Biochemistry.

Transforming growth factor-beta induces the expression of ANF and hypertrophic growth in cultured cardiomyoblast cells through ZAK.

W. Kuo, Chih-Yang Huang, P. Chueh, 2004, Biochemical and biophysical research communications.

Tetramethylpyrazine (TMP) switches energy signalling from the PKCζ-GLUT4-glucose pathway back to the SIRT1-CD36-fatty acid pathway similar to resveratrol to ameliorate cardiac myocyte lipotoxicity

W. Kuo, Dennis Jine-Yuan Hsieh, Tsung‐Jung Ho, 2015 .

Casticin inhibits human prostate cancer DU 145 cell migration and invasion via Ras/Akt/NF-κB signaling pathways.

Jai-Sing Yang, Jing-Gung Chung, F. Tsai, 2019, Journal of food biochemistry.

A minireview of E4BP4/NFIL3 in heart failure

W. Kuo, Chih-Yang Huang, Yueh-min Lin, 2018, Journal of cellular physiology.

Lupeol alters ER stress‐signaling pathway by downregulating ABCG2 expression to induce Oxaliplatin‐resistant LoVo colorectal cancer cell apoptosis

Ray-Jade Chen, V. Viswanadha, Chih-Yang Huang, 2018, Environmental toxicology.

Inhibitory effects of Rhenium-188-labeled Herceptin on prostate cancer cell growth: A possible radioimmunotherapy to prostate carcinoma

Chih-Yang Huang, T. Luo, F. Hsu, 2013, International journal of radiation biology.

Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1.

F. Tsai, Y. Ho, C. Wu, 2015, Molecular cell.

Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling

Yau-Hua Yu, Chih-Yang Huang, Shu-Chun Lin, 2010, Molecular Cancer.

Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis

B. Pasche, F. Tsai, Shih-Ying Wu, 2020, Molecular Cell.

The joint effect of hOGG1 single nucleotide polymorphism and smoking habit on lung cancer in Taiwan.

T. Hsia, Chih-Yang Huang, D. Bau, 2010, Anticancer research.

Lipopolysaccharide upregulates uPA, MMP-2 and MMP-9 via ERK1/2 signaling in H9c2 cardiomyoblast cells

F. Tsai, Wei-Kung Chen, W. Kuo, 2009, Molecular and Cellular Biochemistry.

Green tea epigallocatechin gallate enhances cardiac function restoration through survival signaling expression in diabetes mellitus rats with autologous adipose tissue-derived stem cells.

W. Kuo, L. Pan, Chih-Yang Huang, 2017, Journal of applied physiology.

Green tea EGCG enhances cardiac function restoration through survival signaling 1 expression in DM rats with autologous adipose tissue-derived stem cells 2 3 Running head : Cross effect of EGCG and stem cells on diabetic cardiomyopathy 4 5

W. Kuo, L. Pan, Chih-Yang Huang, 2017 .

Helioxanthin suppresses the cross talk of COX‐2/PGE2 and EGFR/ERK pathway to inhibit Arecoline‐induced Oral Cancer Cell (T28) proliferation and blocks tumor growth in xenografted nude mice

W. Kuo, V. Viswanadha, Chih-Yang Huang, 2016, Environmental toxicology.

A putative novel protein, DEPDC1B, is overexpressed in oral cancer patients, and enhanced anchorage-independent growth in oral cancer cells that is mediated by Rac1 and ERK

Chih-Yang Huang, M. Chou, Ming-cheng Lin, 2014, Journal of Biomedical Science.

Opposing Action of Estrogen Receptors α and β on Tumor Necrosis Factor-α Gene Expression and Caspase-8-mediated Apoptotic Effects in HA22T Cells

J. Ko, Shin-Da Lee, W. Kuo, 2006, Molecular and Cellular Biochemistry.

Activation of IGF2R induces Mitochondrial-dependent Apoptosis through Gαq and Downstream Calcineurin Signaling in Myocardial Cells

F. Tsai, B. Tzang, W. Kuo, 2008 .

Down‐regulation of β‐catenin and the associated migration ability by Taiwanin C in arecoline and 4‐NQO‐induced oral cancer cells via GSK‐3β activation

Chih-Yang Huang, Ming-Cheng Chen, M. Shibu, 2017, Molecular carcinogenesis.

MicroRNA‐210 repression facilitates advanced glycation end‐product (AGE)‐induced cardiac mitochondrial dysfunction and apoptosis via JNK activation

W. Kuo, Kuan-Ho Lin, Chih-Yang Huang, 2021, Journal of cellular biochemistry.

E2/ER β Enhances Calcineurin Protein Degradation and PI3K/Akt/MDM2 Signal Transduction to Inhibit ISO-Induced Myocardial Cell Apoptosis

Ray-Jade Chen, W. Kuo, Kuan-Ho Lin, 2017, International journal of molecular sciences.

Erk phosphorylation reduces the thymoquinone toxicity in human hepatocarcinoma

Chih-Yang Huang, Wei-Jen Ting, Z. Kang, 2021, Environmental toxicology.

Small Molecule Compound Nerolidol attenuates Hypertension induced hypertrophy in spontaneously hypertensive rats through modulation of Mel-18-IGF-IIR signalling.

W. Kuo, Kuan-Ho Lin, Tsung‐Jung Ho, 2021, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Overexpression of anion exchanger 2 in human hepatocellular carcinoma.

Y. Hsieh, Chih-Yang Huang, Jer‐Yuh Liu, 2006, The Chinese journal of physiology.

Resistance to irinotecan (CPT-11) activates epidermal growth factor receptor/nuclear factor kappa B and increases cellular metastasis and autophagy in LoVo colon cancer cells.

F. Tsai, W. Kuo, Tsung‐Jung Ho, 2014, Cancer letters.

Chemiluminescence analysis of antioxidant capacity for serum albumin isolated from healthy or uremic volunteers.

W. Kuo, Chih-Yang Huang, Hsi-Chin Wu, 2016, Luminescence : the journal of biological and chemical luminescence.

Estrogen receptor α (ESR1) over-expression mediated apoptosis in Hep3B cells by binding with SP1 proteins.

Ray-Jade Chen, F. Tsai, W. Kuo, 2013, Journal of molecular endocrinology.

AUTHOR COPY ONLY Estrogen receptor a (ESR1) over- expression mediated apoptosis in Hep3BcellsbybindingwithSP1proteins

Ray-Jade Chen, F. Tsai, W. Kuo, 2013 .

Estrogen receptor a ( ESR 1 ) over-expression mediated apoptosis in Hep 3 BcellsbybindingwithSP 1 proteins

Ray-Jade Chen, F. Tsai, W. Kuo, 2013 .

Rhodiola crenulata and Its Bioactive Components, Salidroside and Tyrosol, Reverse the Hypoxia-Induced Reduction of Plasma-Membrane-Associated Na,K-ATPase Expression via Inhibition of ROS-AMPK-PKCξ Pathway

Chih-Yang Huang, Min-Hui Li, Li-Shian Shi, 2013, Evidence-based complementary and alternative medicine : eCAM.

Observation of surface oxidation resistant Shubnikov-de Haas oscillations in Sb2SeTe2 topological insulator

Ching-Hsiang Hsu, L. Tu, Chih-Yang Huang, 2017 .

LD_(50) OF GAMMA RAY IRRADIATION EMPLOYED IN SULAWESI MEDAKA Oryzias woworae

Chih-Yang Huang, K. Chang, S. Sheen, 2016 .

The multifaceted link between inflammation and human diseases

Ray-Jade Chen, W. Kuo, V. Viswanadha, 2018, Journal of cellular physiology.

Regulation of extracellular signal-regulated protein kinase signaling in human osteosarcoma cells stimulated with nicotine.

W. Kuo, Chih-Yang Huang, Jer‐Yuh Liu, 2005, Journal of periodontal research.

Nerve Regeneration Potential of Protocatechuic Acid in RSC96 Schwann Cells by Induction of Cellular Proliferation and Migration through IGF-IR-PI3K-Akt Signaling.

F. Tsai, Tsung‐Jung Ho, Chih-Yang Huang, 2015, The Chinese journal of physiology.

Roles of p38α and p38β mitogen-activated protein kinase isoforms in human malignant melanoma A375 cells

W. Kuo, Chih-Yang Huang, S. Wen, 2019, International journal of molecular medicine.

Tid1 functions as a tumour suppressor in head and neck squamous cell carcinoma

S. Chiou, Chih-Yang Huang, Shu-Chun Lin, 2009, The Journal of pathology.

MZF-1/Elk-1 interaction domain as therapeutic target for protein kinase Cα-based triple-negative breast cancer cells

M. Hung, Chih-Yang Huang, Jer‐Yuh Liu, 2016, Oncotarget.

CXCL2/CXCR2 axis induces cancer stem cell characteristics in CPT‐11‐resistant LoVo colon cancer cells via Gαi‐2 and Gαq/11

W. Kuo, Tsung‐Jung Ho, V. Viswanadha, 2018, Journal of cellular physiology.

Sumoylation of eukaryotic elongation factor 2 is vital for protein stability and anti‐apoptotic activity in lung adenocarcinoma cells

S. Chiang, Chih-Yang Huang, Tzei-Yi Lin, 2011, Cancer science.

Neferine ameliorates cardiomyoblast apoptosis induced by doxorubicin: possible role in modulating NADPH oxidase/ROS-mediated NFκB redox signaling cascade

Chih-Yang Huang, R. Baskaran, L. B. Priya, 2017, Scientific Reports.

Numerical analysis of airflow alteration in central airways following tracheobronchial stent placement

Tzu-Ching Shih, Jeon-Hor Chen, Hsiu-Mei Liao, 2012, Experimental Hematology & Oncology.

Expression of protein kinase C isoforms in cancerous breast tissue and adjacent normal breast tissue.

F. Tsai, Chih-Yang Huang, Chang-Hai Tsai, 2012, The Chinese journal of physiology.

Diabetes-induced cardiomyopathy is ameliorated by heat-killed Lactobacillus reuteri GMNL-263 in diabetic rats via the repression of the toll-like receptor 4 pathway

Y. Chao, W. Kuo, Tsung‐Jung Ho, 2021, European Journal of Nutrition.

Piperine modulates isoproterenol induced myocardial ischemia through antioxidant and anti-dyslipidemic effect in male Wistar rats.

V. Dhivya, Chih-Yang Huang, L. B. Priya, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

p38 mitogen-activated protein kinase pathway is involved in protein kinase Calpha-regulated invasion in human hepatocellular carcinoma cells.

Yi-Hsien Hsieh, Y. Hsieh, Chih-Yang Huang, 2007, Cancer research.

Resveratrol increases stem cell function in the treatment of damaged pancreas

Ray-Jade Chen, L. Pan, Chih-Yang Huang, 2019, Journal of cellular physiology.

Histone acetylation is essential for ANG‐II‐induced IGF‐IIR gene expression in H9c2 cardiomyoblast cells and pathologically hypertensive rat heart

Fuu-Jen Tsai, Chang-Hai Tsai, Ru-Band Lu, 2012, Journal of cellular physiology.

Endothelin‐1 promotes MMP‐13 production and migration in human chondrosarcoma cells through FAK/PI3K/Akt/mTOR pathways

F. Tsai, Chih-Yang Huang, Chang-Hai Tsai, 2012, Journal of cellular physiology.

The protective effect of piperine against isoproterenol-induced inflammation in experimental models of myocardial toxicity.

V. Dhivya, V. Viswanadha, Chih-Yang Huang, 2020, European journal of pharmacology.

The effects of acupuncture on cardiac muscle cells and blood pressure in spontaneous hypertensive rats.

Yung-Hsien Chang, W. Kuo, Chih-Yang Huang, 2004, Acupuncture & electro-therapeutics research.

Lapatinib-Mediated Cyclooxygenase-2 Expression via Epidermal Growth Factor Receptor/HuR Interaction Enhances the Aggressiveness of Triple-Negative Breast Cancer Cells

C. Tu, Tzung-Chi Huang, M. Hung, 2013, Molecular Pharmacology.

Does early onset cataract increase the risk of ischemic stroke? A nationwide retrospective cohort study

Chih-Yang Huang, Cheng-Li Lin, Tung-sheng Chen, 2017, Internal and Emergency Medicine.

Reduced stem cell aging in exercised human skeletal muscle is enhanced by ginsenoside Rg1

Chih-Yang Huang, A. Alkhatib, G. Condello, 2021, Aging.

Whole-life body composition trajectory and longevity: role of insulin

Yu-Hsuan Lin, Chih-Yang Huang, M. B. Harris, 2021, Aging.

Attenuation of cancer-initiating cells stemness properties by abrogating S100A4 calcium binding ability in head and neck cancers

Chih-Yang Huang, K. Hung, Li-Hao Cheng, 2016, Oncotarget.

Decreased Eccentric Exercise-Induced Macrophage Infiltration in Skeletal Muscle after Supplementation with a Class of Ginseng-Derived Steroids

Ray-Yau Wang, Shin-Da Lee, Chih-Yang Huang, 2014, PloS one.

Exercise training restores IGFIR survival signaling in d-galactose induced-aging rats to suppress cardiac apoptosis

W. Kuo, Tsung‐Jung Ho, Chih-Yang Huang, 2020, Journal of advanced research.

Detailed insight on β-adrenoceptors as therapeutic targets.

Chih-Yang Huang, R. Baskaran, B. Velmurugan, 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis

C. Logothetis, F. Tsai, Xiaohong Xu, 2017, Nature Communications.

MZF-1/Elk-1 Complex Binds to Protein Kinase Cα Promoter and Is Involved in Hepatocellular Carcinoma

Chih-Yang Huang, Jer‐Yuh Liu, Chih-Wei Hsu, 2015, PloS one.

Lumbrokinase from earthworm extract ameliorates second‐hand smoke‐induced cardiac fibrosis

F. Tsai, P. Pai, Tsung‐Jung Ho, 2015, Environmental toxicology.

Cytosolic high-mobility group box protein 1 (HMGB1) and/or PD-1+ TILs in the tumor microenvironment may be contributing prognostic biomarkers for patients with locally advanced rectal cancer who have undergone neoadjuvant chemoradiotherapy

S. Chiang, K. Chao, Chih-Yang Huang, 2018, Cancer Immunology, Immunotherapy.

High density lipoprotein (HDL) reverses palmitic acid induced energy metabolism imbalance by switching CD36 and GLUT4 signaling pathways in cardiomyocyte

Ray-Jade Chen, Chih-Yang Huang, S. Wen, 2017, Journal of cellular physiology.

GABA tea attenuates cardiac apoptosis in spontaneously hypertensive rats (SHR) by enhancing PI3K/Akt‐mediated survival pathway and suppressing Bax/Bak dependent apoptotic pathway

Ray-Jade Chen, Kuan-Ho Lin, V. Viswanadha, 2018, Environmental toxicology.

Cardio Protective Effects of Lumbrokinase and Dilong on Second-Hand Smoke-Induced Apoptotic Signaling in the Heart of a Rat Model.

P. Pai, Tsung‐Jung Ho, Chih-Yang Huang, 2015, The Chinese journal of physiology.

Activated apoptotic and anti‐survival effects on rat hearts with fructose induced metabolic syndrome

Shin-Da Lee, Chih-Yang Huang, Yu-Jung Cheng, 2014, Cell biochemistry and function.

An alternative import pathway of AIF to the mitochondria.

S. Chiang, Chih-Yang Huang, Tzei-Yi Lin, 2011, International journal of molecular medicine.

HGF increases cisplatin resistance via down-regulation of AIF in lung cancer cells.

Chih-Yang Huang, Y. Chiang, K. Chow, 2008, American journal of respiratory cell and molecular biology.

San Huang Shel Shin Tang beta-cyclodextrin complex augmented the hepatoprotective effects against carbon tetrachloride-induced acute hepatotoxicity in rats

W. Kuo, Chih-Yang Huang, Wei-Jen Ting, 2016, BMC Complementary and Alternative Medicine.

Anti-apoptosis effects on hearts of SHSST cyclodextrin complex in a carbon tetrachloride-induced cirrhotic cardiomyopathy rat model.

Cheng-Hsun Yang, F. Tsai, P. Pai, 2015, The Chinese journal of physiology.

Dipeptide IF prevents the effects of hypertension‐induced Alzheimer's disease on long‐term memory in the cortex of spontaneously hypertensive rats

Tsung‐Jung Ho, Chih-Yang Huang, Yung-Ming Chang, 2019, Environmental toxicology.

Combinational treatment of all-trans retinoic acid (ATRA) and bisdemethoxycurcumin (BDMC)-induced apoptosis in liver cancer Hep3B cells.

Jai-Sing Yang, Jing-Gung Chung, F. Tsai, 2019, Journal of food biochemistry.

Effect of dehydroepiandrosterone administration on recovery from mix-type exercise training-induced muscle damage

Shin-Da Lee, J. Ivy, Chih-Yang Huang, 2012, European Journal of Applied Physiology.

Effects of human parvovirus B19 on expression of defensins and Toll-like receptors.

B. Tzang, Chih-Yang Huang, Chun-Ching Chiu, 2011, The Chinese journal of physiology.

EFFECTS OF LIGUSTICUM CHUANXIONG ON INJURED PERIPHERAL NERVE IN RATS

T. Lu, Chih-Yang Huang, C. Yao, 2010 .

Relationship between polymorphisms of nucleotide excision repair genes and oral cancer risk in Taiwan: evidence for modification of smoking habit.

F. Tsai, M. Tsai, Chih-Yang Huang, 2007, The Chinese journal of physiology.

Leech extract: a candidate cardioprotective against hypertension-induced cardiac hypertrophy and fibrosis.

Yu-LanYeh, W. Kuo, V. Viswanadha, 2020, Journal of Ethnopharmacology.

Glycyrrhiza uralensis root extract ameliorates high glucose-induced renal proximal tubular fibrosis by attenuating tubular epithelial-myofibroblast transdifferentiation by targeting TGF-β1/Smad/Stat3 pathway.

Tsung‐Jung Ho, Chih-Yang Huang, C. Kuo, 2022, Journal of food biochemistry.

Upregulation of IGF‐IIRα intensifies doxorubicin‐induced cardiac damage

Ray-Jade Chen, W. Kuo, P. Pai, 2019, Journal of cellular biochemistry.

ZAK induces cardiomyocyte hypertrophy and brain natriuretic peptide expression via p38/JNK signaling and GATA4/c-Jun transcriptional factor activation

P. Pai, V. Viswanadha, Chih-Yang Huang, 2015, Molecular and Cellular Biochemistry.

Alpinia oxyphylla Miq extract ameliorates cardiac fibrosis associated with D‐galactose induced aging in rats

W. Kuo, Hsin-Nung Chang, V. Viswanadha, 2018, Environmental toxicology.

RANKL increases migration of human lung cancer cells through intercellular adhesion molecule‐1 up‐regulation

F. Tsai, Chih-Yang Huang, Chang-Hai Tsai, 2011, Journal of cellular biochemistry.

Transglutaminase inhibitor cystamine alleviates the abnormality in liver from NZB/W F1 mice.

B. Tzang, Chih-Yang Huang, Chang-Hai Tsai, 2008, European journal of pharmacology.

17β-Estradiol and/or Estrogen Receptor β Attenuate the Autophagic and Apoptotic Effects Induced by Prolonged Hypoxia Through HIF-1α-Mediated BNIP3 and IGFBP-3 Signaling Blockage

W. Kuo, Dennis Jine-Yuan Hsieh, P. Pai, 2015, Cellular Physiology and Biochemistry.

Cardiac Fas Receptor‐dependent Apoptotic Pathway in Obese Zucker Rats

F. Tsai, B. Tzang, Shin-Da Lee, 2007, Obesity.

Attenuation of the LPS‐induced, ERK‐mediated upregulation of fibrosis‐related factors FGF‐2, uPA, MMP‐2, and MMP‐9 by Carthamus tinctorius L in cardiomyoblasts

Tsung‐Jung Ho, Chih-Yang Huang, H. Hsu, 2017, Environmental toxicology.

17β-Estradiol and/or estrogen receptor alpha blocks isoproterenol-induced calcium accumulation and hypertrophy via GSK3β/PP2A/NFAT3/ANP pathway

P. Pai, Tsung‐Jung Ho, Chih-Yang Huang, 2017, Molecular and Cellular Biochemistry.

Significant association of XPD Asp312Asn polymorphism with breast cancer in Taiwanese patients.

Chih-Yang Huang, D. Bau, Yueh-Sheng Chen, 2010, The Chinese journal of physiology.

CD133/Src Axis Mediates Tumor Initiating Property and Epithelial-Mesenchymal Transition of Head and Neck Cancer

Chih-Yang Huang, Shu-Chun Lin, T. Chuang, 2011, PloS one.

Reversion of glucocorticoid-induced senescence and collagen synthesis decrease by LY294002 is mediated through p38 in skin

W. Kuo, Chih-Yang Huang, S. Wen, 2022, International journal of biological sciences.

Eriobotrya japonica ameliorates cardiac hypertrophy in H9c2 cardiomyoblast and in spontaneously hypertensive rats

W. Kuo, V. Viswanadha, Chih-Yang Huang, 2018, Environmental toxicology.

Hepatoprotective Effects of Traditional Chinese Medicine on Liver Fibrosis from Ethanol Administration following Partial Hepatectomy.

Dennis Jine-Yuan Hsieh, Kuan-Ho Lin, L. Pan, 2015, The Chinese journal of physiology.

Tid1‐S attenuates LPS‐induced cardiac hypertrophy and apoptosis through ER‐a mediated modulation of p‐PI3K/p‐Akt signaling cascade

Ray-Jade Chen, V. Viswanadha, Chih-Yang Huang, 2019, Journal of cellular biochemistry.

Antioxidant Sirt1/Akt axis expression in resveratrol pretreated adipose‐derived stem cells increases regenerative capability in a rat model with cardiomyopathy induced by diabetes mellitus

W. Kuo, Tsung‐Jung Ho, Chih-Yang Huang, 2021, Journal of cellular physiology.

ERK1/2 mediates the lipopolysaccharide-induced upregulation of FGF-2, uPA, MMP-2, MMP-9 and cellular migration in cardiac fibroblasts.

W. Kuo, V. Viswanadha, Chih-Yang Huang, 2019, Chemico-biological interactions.

Protective effects of diallyl trisulfide (DATS) against doxorubicin-induced inflammation and oxidative stress in the brain of rats.

W. Kuo, Tsung‐Jung Ho, Chih-Yang Huang, 2020, Free radical biology & medicine.

Anti-inflammatory effects of probiotic Lactobacillus paracasi on ventricles of BALB/C mice treated with ovalbumin.

Chih-Yang Huang, Chang-Hai Tsai, Mu‐hsin Chang, 2012, The Chinese journal of physiology.

Suppression of tumorigenicity of human hepatocellular carcinoma cells by antisense oligonucleotide MZF-1.

Y. Hsieh, Chih-Yang Huang, Jer‐Yuh Liu, 2007, The Chinese journal of physiology.

Tetramethylpyrazine Ameliorated Hypoxia-Induced Myocardial Cell Apoptosis via HIF-1α/JNK/p38 and IGFBP3/BNIP3 Inhibition to Upregulate PI3K/Akt Survival Signaling

Wei-Kung Chen, W. Kuo, P. Pai, 2015, Cellular Physiology and Biochemistry.

Longevity, tumor, and physical vitality in rats consuming ginsenoside Rg1

Chih-Yang Huang, C. Kuo, Suchada Saovieng, 2021, Journal of ginseng research.

Attenuated Cardiac Mitochondrial-Dependent Apoptotic Effects by Li-Fu Formula in Hamsters Fed with a Hypercholesterol Diet

Chieh-Hsi Wu, F. Tsai, B. Tzang, 2011, Evidence-based complementary and alternative medicine : eCAM.

' s response to reviews Title : Protective effect of Danggui ( Radix Angelicae Sinensis ) on angiotensin II-induced apoptosis in H 9 c 2 cardiomyoblast cells

W. Kuo, Chih-Yang Huang, Peng-Yu Liu, 2014 .

Null effect of ginsenoside Rb1 on improving glycemic status in men during a resistance training recovery

Shin-Da Lee, Chih-Yang Huang, Wei-Hsiang Chang, 2015, Journal of the International Society of Sports Nutrition.

Timing of Applying Electrical Stimulation Is an Important Factor Deciding the Success Rate and Maturity of Regenerating Rat Sciatic Nerves

Chun-Hsu Yao, Fuu-Jen Tsai, Yueh-Sheng Chen, 2010, Neurorehabilitation and neural repair.

Oolong tea prevents cardiomyocyte loss against hypoxia by attenuating p‐JNK mediated hypertrophy and enhancing P‐IGF1R, p‐akt, and p‐Badser136 activity and by fortifying NRF2 antioxidation system

Ray-Jade Chen, W. Kuo, V. Viswanadha, 2018, Environmental toxicology.

LPS‐enhanced IGF‐IIR pathway to induce H9c2 cardiomyoblast cell hypertrophy was attenuated by Carthamus tinctorius extract via IGF‐IR activation

Dennis Jine-Yuan Hsieh, V. Viswanadha, Chih-Yang Huang, 2019, Environmental toxicology.

Epigallocatechin-3-gallate preconditioned Adipose-derived Stem Cells confer Neuroprotection in aging rat brain

W. Kuo, Dennis Jine-Yuan Hsieh, Chih-Yang Huang, 2020, International journal of medical sciences.

Review of Danshen: From its metabolism to possible mechanisms of its biological activities

Shin-Da Lee, Chih-Yang Huang, R. Kiefer, 2021 .

Hypoxia suppresses myocardial survival pathway through HIF-1α-IGFBP-3-dependent signaling and enhances cardiomyocyte autophagic and apoptotic effects mainly via FoxO3a-induced BNIP3 expression

W. Kuo, Kuan-Ho Lin, V. Viswanadha, 2016, Growth factors.

Distinct subpopulations of head and neck cancer cells with different levels of intracellular reactive oxygen species exhibit diverse stemness, proliferation, and chemosensitivity.

Chih-Yang Huang, S. Chou, Cheng-Chieh Yang, 2014, Cancer research.

Tumor and Stem Cell Biology Distinct Subpopulations of Head and Neck Cancer Cells withDifferent Levelsof IntracellularReactiveOxygenSpecies Exhibit Diverse Stemness , Proliferation , and Chemosensitivity

Chih-Yang Huang, S. Chou, Cheng-Chieh Yang, 2014 .

Suppression of Plasminogen Activators and the MMP-2/-9 Pathway by a Zanthoxylum avicennae Extract to Inhibit the HA22T Human Hepatocellular Carcinoma Cell Migration and Invasion Effects in Vitro and in Vivo via Phosphatase 2A Activation

F. Tsai, W. Kuo, P. Pai, 2013, Bioscience, biotechnology, and biochemistry.

Lung Cancer in Taiwan

T. Hsia, Chih-Yang Huang, D. Bau, 2010 .

Protective effects of galangin against H2O2‐induced aging via the IGF‐1 signaling pathway in human dermal fibroblasts

W. Kuo, Chih-Yang Huang, S. Wen, 2020, Environmental toxicology.

Clinical Characteristics Change and the Heart Rate Variability of Subjects with Metabolic Syndrome in the Weight Loss Program

Chih-Yang Huang, Fuu-Jen Tsai, Chang-Hai Tsai, 2011, 2011 IEEE 11th International Conference on Bioinformatics and Bioengineering.

Intracerebral transplantation of autologous adipose‐derived stem cells for chronic ischemic stroke: A phase I study

H. Harn, Chih-Yang Huang, Shinn-Zong Lin, 2021, Journal of tissue engineering and regenerative medicine.

JNK suppression is essential for 17β-Estradiol inhibits prostaglandin E2-Induced uPA and MMP-9 expressions and cell migration in human LoVo colon cancer cells

F. Tsai, Wei-Kung Chen, W. Kuo, 2011, Journal of Biomedical Science.

The Protective Effects of Clams on Hypercholesterolemia in Late-Stage Triple-Transgenic Alzheimer’s Diseased Mice Hearts

Chih-Yang Huang, C. Hsieh, Y. Yeh, 2018, Marine drugs.

Albuminuria is strongly associated with arterial stiffness, especially in diabetic or hypertensive subjects--a population-based study (Taichung Community Health Study, TCHS).

L. Davidson, Chih-Yang Huang, F. Pi‐Sunyer, 2010, Atherosclerosis.

Single-nucleotide polymorphism of the Exo1 gene: association with gastric cancer susceptibility and interaction with smoking in Taiwan.

C. Hsiung, Chih-Yang Huang, D. Bau, 2009, The Chinese journal of physiology.

Diallyl trisulfide suppresses doxorubicin‐induced cardiomyocyte apoptosis by inhibiting MAPK/NF‐κB signaling through attenuation of ROS generation

W. Kuo, P. Pai, Chih-Yang Huang, 2018, Environmental toxicology.

Structure Based Design of N-(3-((1H-Pyrazolo[3,4-b]pyridin-5-yl)ethynyl)benzenesulfonamides as Selective Leucine-Zipper and Sterile-α Motif Kinase (ZAK) Inhibitors.

Yan Zhang, Yong Xu, Chih-Yang Huang, 2017, Journal of medicinal chemistry.

Cell Cycle Regulation in the Estrogen Receptor Beta (ESR2)-Overexpressing Hep3B Hepatocellular Carcinoma Cell Line.

Chih-Yang Huang, S. Wen, Yueh-min Lin, 2015, The Chinese journal of physiology.

17β-Estradiol inhibits prostaglandin E2-induced COX-2 expressions and cell migration by suppressing Akt and ERK1/2 signaling pathways in human LoVo colon cancer cells

B. Tzang, Chih-Yang Huang, Chung-Jung Liu, 2010, Molecular and Cellular Biochemistry.

Thymoquinone induces caspase-independent, autophagic cell death in CPT-11-resistant lovo colon cancer via mitochondrial dysfunction and activation of JNK and p38.

W. Kuo, Dennis Jine-Yuan Hsieh, Tsung‐Jung Ho, 2015, Journal of agricultural and food chemistry.

Alpinate Oxyphyllae Fructus (Alpinia Oxyphylla Miq) Extracts Inhibit Angiotensin-II Induced Cardiac Apoptosis in H9c2 Cardiomyoblast Cells

Ray-Jade Chen, F. Tsai, B. Tzang, 2013, Bioscience, biotechnology, and biochemistry.

Estradiol agonists inhibit human LoVo colorectal-cancer cell proliferation and migration through p53.

W. Kuo, Chih-Yang Huang, H. Hsu, 2014, World journal of gastroenterology.

Ocimum gratissmum aqueous extract reduces plasma lipid in hypercholesterol-fed hamsters

T. Lai, Chih-Yang Huang, Wei-Jen Ting, 2016, International journal of medical sciences.

The preventive effects of edible folic acid on cardiomyocyte apoptosis and survival in early onset triple‐transgenic Alzheimer's disease model mice

Ray-Jade Chen, W. Kuo, Kuan-Ho Lin, 2018, Environmental toxicology.

Resveratrol enhanced FOXO3 phosphorylation via synergetic activation of SIRT1 and PI3K/Akt signaling to improve the effects of exercise in elderly rat hearts

W. Kuo, P. Pai, Tsung‐Jung Ho, 2014, AGE.

Silymarin Accelerates Liver Regeneration after Partial Hepatectomy

L. Pan, Chih-Yang Huang, Yueh-min Lin, 2015, Evidence-based complementary and alternative medicine : eCAM.

The Effect of Elephantopus scaber L. on Liver Regeneration after Partial Hepatectomy

F. Tsai, B. Tzang, Tsung‐Jung Ho, 2013, Evidence-based complementary and alternative medicine : eCAM.

Active Component of Antrodia cinnamomea Mycelia Targeting Head and Neck Cancer Initiating Cells through Exaggerated Autophagic Cell Death

Chih-Yang Huang, Shu-Chun Lin, Chung-Ji Liu, 2013, Evidence-based complementary and alternative medicine : eCAM.

Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy.

Ray-Jade Chen, F. Tsai, W. Kuo, 2017, International journal of cardiology.

Effects of Different Concentrations of Collagenous Peptide from Fish Scales on Osteoblast Proliferation and Osteoclast Resorption.

Chih-Yang Huang, C. Yao, Tzu-Min Chan, 2016, The Chinese journal of physiology.

β-catenin plays a key role in metastasis of human hepatocellular carcinoma.

F. Tsai, W. Kuo, Chih-Yang Huang, 2011, Oncology reports.

Alpinate Oxyphyllae extracts enhance the longevity and homing of mesenchymal stem cells and augment their protection against senescence in H9c2 cells

Ray-Jade Chen, V. Viswanadha, Chih-Yang Huang, 2018, Journal of cellular physiology.

Citrus medica var. sarcodactylis (Foshou) activates fibroblast growth factor-2 signaling to induce migration of RSC96 Schwann cells.

F. Tsai, W. Kuo, L. Pan, 2014, The American journal of Chinese medicine.

The Heart Protection Effect of Alcalase Potato Protein Hydrolysate Is through IGF1R-PI3K-Akt Compensatory Reactivation in Aging Rats on High Fat Diets

P. Pai, Chih-Yang Huang, Wei-Jen Ting, 2015, International journal of molecular sciences.

Hyperglycemia-Induced Cardiac Damage Is Alleviated by Heat-Inactivated Lactobacillus reuteri GMNL-263 via Activation of the IGF1R Survival Pathway

Ray-Jade Chen, W. Kuo, Chih-Yang Huang, 2021, Probiotics and Antimicrobial Proteins.

Identification of an autoantibody against the proliferating cell nuclear antigen from a patient with systemic lupus erythematosus.

B. Tzang, Chih-Yang Huang, J. Lan, 2010, The Chinese journal of physiology.

Clinical significance of programmed death 1 ligand-1 (CD274/PD-L1) and intra-tumoral CD8+ T-cell infiltration in stage II–III colorectal cancer

S. Chiang, K. Chao, Chih-Yang Huang, 2018, Scientific Reports.

Over-expressed estrogen receptor-alpha up-regulates hTNF-alpha gene expression and down-regulates beta-catenin signaling activity to induce the apoptosis and inhibit proliferation of LoVo colon cancer cells.

Shin-Da Lee, W. Kuo, Chih-Yang Huang, 2006, Molecular and cellular biochemistry.

Apoptotic effects of over-expressed estrogen receptor-beta on LoVo colon cancer cell is mediated by p53 signalings in a ligand-dependent manner.

Shin-Da Lee, W. Kuo, Chih-Yang Huang, 2006, The Chinese journal of physiology.

Taohe Chengqi Tang ameliorates acute liver injury induced by carbon tetrachloride in rats.

F. Tsai, W. Kuo, Chih-Yang Huang, 2010, Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine.

Can mesenchymal stem cell lysate reverse aging?

P. Singal, Chih-Yang Huang, C. Kao, 2018, Aging.

AXL is crucial for E1A‐enhanced therapeutic efficiency of EGFR tyrosine kinase inhibitors through NFI in breast cancer

Chih-Yang Huang, Kuan-Chou Chen, S. Sung, 2021, Environmental toxicology.

Estrogen and ERα enhanced β‐catenin degradation and suppressed its downstream target genes to block the metastatic function of HA22T hepatocellular carcinoma cells via modulating GSK‐3β and β‐TrCP expression

Chih-Yang Huang, Ming-Cheng Chen, H. Hsu, 2017, Environmental toxicology.

Upregulation of tumor PD-L1 by neoadjuvant chemoradiotherapy (neoCRT) confers improved survival in patients with lymph node metastasis of locally advanced rectal cancers

S. Chiang, K. Chao, Chih-Yang Huang, 2018, Cancer Immunology, Immunotherapy.

Protective effect of autologous transplantation of resveratrol preconditioned adipose‐derived stem cells in the treatment of diabetic liver dysfunction in rat model

Ray-Jade Chen, V. Viswanadha, Chih-Yang Huang, 2019, Journal of tissue engineering and regenerative medicine.

17β-Estradiol and/or estrogen receptor alpha blocks isoproterenol-induced calcium accumulation and hypertrophy via GSK3β/PP2A/NFAT3/ANP pathway

P. Pai, Tsung‐Jung Ho, Chih-Yang Huang, 2017, Molecular and Cellular Biochemistry.

Neuroprotective Effects of Probiotic Lactobacillus reuteri GMNL-263 in the Hippocampus of Streptozotocin-Induced Diabetic Rats

W. Kuo, Tsung‐Jung Ho, Chih-Yang Huang, 2022, Probiotics and Antimicrobial Proteins.

The molecular mechanisms underlying arecoline-induced cardiac fibrosis in rats

Ray-Jade Chen, H. Ou, Tsung‐Jung Ho, 2021, Open life sciences.

Effect of acute DHEA administration on free testosterone in middle-aged and young men following high-intensity interval training

J. Ivy, Chih-Yang Huang, C. Kuo, 2013, European Journal of Applied Physiology.

Cordycepin Attenuates Palmitic Acid-Induced Inflammation and Apoptosis of Vascular Endothelial Cells through Mediating PI3K/Akt/eNOS Signaling Pathway.

H. Ou, Pei-Ling Hsieh, Tsung‐Jung Ho, 2021, The American journal of Chinese medicine.

ZAK negatively regulates RhoGDIβ-induced Rac1-mediated hypertrophic growth and cell migration

Chih-Yang Huang, Kuan-Yu Liu, M. Chou, 2009, Journal of Biomedical Science.

Design, Synthesis, and Structure-Activity Relationships of 1,2,3-Triazole Benzenesulfonamides as New Selective Leucine-Zipper and Sterile-α Motif Kinase (ZAK) Inhibitors.

Chih-Yang Huang, M. Shibu, C. Yun, 2019, Journal of medicinal chemistry.

Doxorubicin induces ZAKα overexpression with a subsequent enhancement of apoptosis and attenuation of survivability in human osteosarcoma cells

W. Kuo, V. Viswanadha, Chih-Yang Huang, 2018, Environmental toxicology.

Exploring the molecular mechanisms of OSU-03012 on vascular smooth muscle cell proliferation

Chieh-Hsi Wu, S. Tsai, W. Kuo, 2010, Molecular and Cellular Biochemistry.

p38 mitogen-activated protein kinase pathway is involved in protein kinase Calpha-regulated invasion in human hepatocellular carcinoma cells.

Y. Hsieh, Chih-Yang Huang, Jer‐Yuh Liu, 2007, Cancer research.

Caveolin‐1 Secreted from Adipose Tissues and Adipocytes Functions as an Adipogenesis Enhancer

Chih-Yang Huang, M. Hung, Chia-Chu Chang, 2017, Obesity.

Reducing body fat with altitude hypoxia training in swimmers: role of blood perfusion to skeletal muscles.

Shin-Da Lee, Chih-Yang Huang, M. B. Harris, 2013, The Chinese journal of physiology.

Chemoresistance-Associated Silencing of miR-4454 Promotes Colorectal Cancer Aggression through the GNL3L and NF-κB Pathway

W. Kuo, V. Viswanadha, Chih-Yang Huang, 2020, Cancers.

Activation of estrogen receptors with E2 downregulates peroxisome proliferator-activated receptor γ in hepatocellular carcinoma.

F. Tsai, Tsung‐Jung Ho, Chih-Yang Huang, 2013, Oncology reports.

Protein supplementation enhances cerebral oxygenation during exercise in elite basketball players.

Chih‐Yen Chen, Chih-Yang Huang, C. Kuo, 2018, Nutrition.

Lactate dehydrogenase downregulation mediates the inhibitory effect of diallyl trisulfide on proliferation, metastasis, and invasion in triple‐negative breast cancer

K. Ting, W. Kuo, V. Viswanadha, 2017, Environmental toxicology.

Tanshinone IIA inhibits Leu27IGF‐II‐induced insulin‐like growth factor receptor II signaling and myocardial apoptosis via estrogen receptor‐mediated Akt activation

W. Kuo, Dennis Jine-Yuan Hsieh, Tsung‐Jung Ho, 2021, Environmental toxicology.

Normalization effect of sports training on blood pressure in hypertensives

Shin-Da Lee, Chih-Yang Huang, C. Kuo, 2010, Journal of sports sciences.

Taiwanin C elicits apoptosis in arecoline and 4‐nitroquinoline‐1‐oxide‐induced oral squamous cell carcinoma cells and hinders proliferation via epidermal growth factor receptor/PI3K suppression

Chih-Yang Huang, M. Shibu, Yueh-min Lin, 2019, Environmental toxicology.

Attenuated Effects of Deep-Sea Water on Hepatic Apoptosis in STZ-Induced Diabetic Rats.

B. Tzang, Chih-Yang Huang, Chun-Ching Chiu, 2015, The Chinese journal of physiology.

E2/ERβ Inhibits PPARα to Regulate Cell-Proliferation and Enhance Apoptosis in Hep3B-Hepatocellular Carcinoma

W. Kuo, Tsung‐Jung Ho, V. Viswanadha, 2017, Pathology & Oncology Research.

Apoptotic and anti-proliferative effects of 17beta-estradiol and 17beta-estradiol-like compounds in the Hep3B cell line.

Shin-Da Lee, W. Kuo, Chih-Yang Huang, 2006, Molecular and Cellular Biochemistry.

Thymoquinone suppresses migration of LoVo human colon cancer cells by reducing prostaglandin E2 induced COX-2 activation

W. Kuo, Chih-Yang Huang, H. Shih, 2017, World journal of gastroenterology.

Selective Activation of ZAK β Expression by 3-Hydroxy-2-Phenylchromone Inhibits Human Osteosarcoma Cells and Triggers Apoptosis via JNK Activation

W. Kuo, Chih-Yang Huang, Tso-fu Wang, 2020, International journal of molecular sciences.

Paeoniae alba Radix Promotes Peripheral Nerve Regeneration

F. Tsai, Chih-Yang Huang, C. Yao, 2011, Evidence-based complementary and alternative medicine : eCAM.

CHIP-overexpressing Wharton's jelly-derived mesenchymal stem cells attenuate hyperglycemia-induced oxidative stress-mediated kidney injuries in diabetic rats.

Ray-Jade Chen, W. Kuo, Tsung‐Jung Ho, 2021, Free radical biology & medicine.

Impact of LPS-Induced Cardiomyoblast Cell Apoptosis Inhibited by Earthworm Extracts

W. Kuo, P. Pai, Chih-Yang Huang, 2014, Cardiovascular Toxicology.

All-Trans Retinoic Acid Induces DU145 Cell Cycle Arrest through Cdk5 Activation

S. Hsu, Chih-Yang Huang, E. Lin, 2014, Cellular Physiology and Biochemistry.

Taiwanin C selectively inhibits arecoline and 4‐NQO‐induced oral cancer cell proliferation via ERK1/2 inactivation

Y. Kuo, Kuan-Ho Lin, V. Viswanadha, 2017, Environmental toxicology.

EFFECTS OF DEEP-SEA WATER ON CARDIAC ABNORMALITY IN HIGH-CHOLESTEROL DIETARY MICE

F. Tsai, B. Tzang, Chih-Yang Huang, 2012 .

Supplementary heat-killed Lactobacillus reuteri GMNL-263 ameliorates hyperlipidaemic and cardiac apoptosis in high-fat diet-fed hamsters to maintain cardiovascular function

W. Kuo, Tsung‐Jung Ho, V. Viswanadha, 2015, British Journal of Nutrition.

Contrasting actions of ginsenosides Rb1 and Rg1 on glucose tolerance in rats

Chih-Yang Huang, R. Chaunchaiyakul, N. Leelayuwat, 2019, The Chinese journal of physiology.

Cardiac Fas-Dependent and Mitochondria-Dependent Apoptotic Pathways in a Transgenic Mouse Model of Huntington’s Disease

M. Chiang, Shin-Da Lee, Chih-Yang Huang, 2016, Cardiovascular Toxicology.

Down regulation of IGF-I and IGF-IR gene expression in right atria tissue of ventricular septal defect infants with right atria hypoxemia.

F. Tsai, Shin-Da Lee, W. Kuo, 2007, Clinica chimica acta; international journal of clinical chemistry.

Retraction Retracted : Silymarin Accelerates Liver Regeneration after Partial Hepatectomy Evidence-Based Complementary and Alternative Medicine

L. Pan, Chih-Yang Huang, Yueh-min Lin, 2017 .

Retraction Retracted : The Effect of Elephantopus scaber L . on Liver Regeneration after Partial Hepatectomy Evidence-Based Complementary and Alternative Medicine

F. Tsai, B. Tzang, Tsung‐Jung Ho, 2017 .

Environmental tobacco smoke increases autophagic effects but decreases longevity associated with Sirt-1 protein expression in young C57BL mice hearts

W. Kuo, V. Viswanadha, Chih-Yang Huang, 2016, Oncotarget.

Aerobic exercise induces tumor suppressor p16INK4a expression of endothelial progenitor cells in human skeletal muscle

J. Ivy, Chih-Yang Huang, Yung-Yang Liu, 2020, Aging.

Andrographis paniculata extract attenuates pathological cardiac hypertrophy and apoptosis in high-fat diet fed mice.

W. Kuo, Kuan-Ho Lin, V. Viswanadha, 2016, Journal of ethnopharmacology.

Gelsolin (GSN) induces cardiomyocyte hypertrophy and BNP expression via p38 signaling and GATA-4 transcriptional factor activation

F. Tsai, P. Pai, Tsung‐Jung Ho, 2014, Molecular and Cellular Biochemistry.

Does Chinese calligraphy therapy reduce neuropsychiatric symptoms: a systematic review and meta-analysis

Chih-Yang Huang, W. Ouyang, Kuan‐Yu Chu, 2018, BMC Psychiatry.

Hyperglycemia and advanced glycation end products (AGEs) suppress the differentiation of 3T3-L1 preadipocytes

Chih-Yang Huang, G. Chang, Chung‐ho Chang, 2017, Oncotarget.

HSP40 co-chaperone protein Tid1 suppresses metastasis of head and neck cancer by inhibiting Galectin-7-TCF3-MMP9 axis signaling

Chih-Yang Huang, Yi-Chen Wu, Te-Chang Lee, 2018, Theranostics.

Inhibition of Protein Phosphatase 1 Stimulates Noncanonical ER Stress eIF2α Activation to Enhance Fisetin-induced Chemosensitivity in HDAC Inhibitor-resistant Hepatocellular Carcinoma Cells

W. Kuo, V. Viswanadha, Chih-Yang Huang, 2019, Cancers.

Prostaglandin E2-Induced COX-2 Expressions via EP2 and EP4 Signaling Pathways in Human LoVo Colon Cancer Cells

Ray-Jade Chen, V. Viswanadha, Chih-Yang Huang, 2017, International journal of molecular sciences.

Mitochondrial co-chaperone protein Tid1 is required for energy homeostasis during skeletal myogenesis

Chih-Yang Huang, K. Hung, Li-Hao Cheng, 2016, Stem Cell Research & Therapy.

Thymoquinone induces caspase-independent, autophagic cell death in CPT-11-resistant lovo colon cancer via mitochondrial dysfunction and activation of JNK and p38.

W. Kuo, Tsung‐Jung Ho, Chih-Yang Huang, 2015, Journal of agricultural and food chemistry.

Sumoylation of eukaryotic elongation factor 2 is vital for protein stability and anti‐apoptotic activity in lung adenocarcinoma cells

S. Chiang, Chih-Yang Huang, Tzei-Yi Lin, 2011, Cancer science.

Effects of oral Lactobacillus administration on antioxidant activities and CD4+CD25+forkhead box P3 (FoxP3)+ T cells in NZB/W F1 mice

B. Tzang, Chih-Yang Huang, T. Hsu, 2017, British Journal of Nutrition.

Akt mediates 17β-estradiol and/or estrogen receptor-α inhibition of LPS-induced tumor necresis factor-α expression and myocardial cell apoptosis by suppressing the JNK1/2-NFκB pathway

F. Tsai, B. Tzang, W. Kuo, 2009, Journal of cellular and molecular medicine.

Exercise training enhanced SIRT1 longevity signaling replaces the IGF1 survival pathway to attenuate aging-induced rat heart apoptosis

W. Kuo, P. Pai, Tsung‐Jung Ho, 2014, AGE.

Leu27IGF2 plays an opposite role to IGF1 to induce H9c2 cardiomyoblast cell apoptosis via Galphaq signaling.

Ray-Jade Chen, F. Tsai, Chih-Yang Huang, 2009, Journal of molecular endocrinology.

TRAF6 Restricts p53 Mitochondrial Translocation, Apoptosis, and Tumor Suppression.

F. Tsai, K. Watabe, Xiaohong Xu, 2016, Molecular cell.

Tanshinone-induced ERs suppresses IGFII activation to alleviate Ang II-mediated cardiac hypertrophy

Ray-Jade Chen, W. Kuo, P. Pai, 2017, Journal of receptor and signal transduction research.

D‐galactose‐induced toxicity associated senescence mitigated by alpinate oxyphyllae fructus fortified adipose‐derived mesenchymal stem cells

W. Kuo, Chih-Yang Huang, M. Shibu, 2020, Environmental toxicology.

Distinct population of highly malignant cells in a head and neck squamous cell carcinoma cell line established by xenograft model

S. Chiou, Chih-Yang Huang, Shu-Chun Lin, 2009, Journal of Biomedical Science.

Structure Based Design of N-(3-((1H-Pyrazolo[3,4-b]pyridin-5-yl)ethynyl)benzenesulfonamides as Selective Leucine-Zipper and Sterile-α Motif Kinase (ZAK) Inhibitors.

Yan Zhang, Yong Xu, Chih-Yang Huang, 2017, Journal of medicinal chemistry.

Effects of rhodiola crenulata on mice hearts under severe sleep apnea

Shin-Da Lee, P. Pai, Chih-Yang Huang, 2015, BMC Complementary and Alternative Medicine.

CCN6 enhances ICAM‐1 expression and cell motility in human chondrosarcoma cells

F. Tsai, Chih-Yang Huang, Chang-Hai Tsai, 2012, Journal of cellular physiology.

Thymoquinone induces apoptosis in oral cancer cells through p38β inhibition.

Ray-Jade Chen, Chih-Yang Huang, Wei-Jen Ting, 2013, The American journal of Chinese medicine.

Pre-exercise Carbohydrate Drink Adding Protein Improves Post-exercise Fatigue Recovery

Chih-Yang Huang, C. Kuo, S. Hamzah, 2021, Frontiers in Physiology.

Angiotensin II receptor blocker irbesartan attenuates sleep apnea–induced cardiac apoptosis and enhances cardiac survival and Sirtuin 1 upregulation

Shin-Da Lee, P. Pai, Chih-Yang Huang, 2021, Sleep and Breathing.

Effects of garlic oil on interleukin-6 mediated cardiac hypertrophy in hypercholesterol-fed hamsters.

Chieh-Hsi Wu, M. Fan, P. Pai, 2017, The Chinese journal of physiology.

Tid1 functions as a tumour suppressor in head and neck squamous cell carcinoma

S. Chiou, Chih-Yang Huang, Shu-Chun Lin, 2009, The Journal of pathology.

Does ovulation affect performance in tennis players?

Chih-Yang Huang, Yung-Shen Tsai, C. Kuo, 2018, BMJ Open Sport & Exercise Medicine.

Correction for: Swimming exercise stimulates IGF1/PI3K/Akt and AMPK/SIRT1/PGC1α survival signaling to suppress apoptosis and inflammation in aging hippocampus

W. Kuo, Tsung‐Jung Ho, Chih-Yang Huang, 2020, Aging.