Ying Xu

发表

Curcumin produces neuroprotective effects via activating brain-derived neurotrophic factor/TrkB-dependent MAPK and PI-3K cascades in rodent cortical neurons

Rui Wang, Xue-jun Li, Xueyang Pan, 2010, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Inhibition of Cyclic Nucleotide Phosphodiesterases to Regulate Memory

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2014 .

The antidepressant effects of curcumin in the forced swimming test involve 5-HT1 and 5-HT2 receptors.

Rui Wang, Xue-jun Li, Yu-Hua Li, 2008, European journal of pharmacology.

Antidepressant Drugs and Phosphodiesterases

Ying Xu, Han-Ting Zhang, Zhuoyou Chen, 2016 .

Reduced phosphodiesterase-2 activity in the amygdala results in anxiolytic-like effects on behavior in mice

J. O'Donnell, Qiang Wu, Ying Xu, 2019, Journal of psychopharmacology.

Ferulic acid increases pain threshold and ameliorates depression-like behaviors in reserpine-treated mice: behavioral and neurobiological analyses

J. O'Donnell, Ying Xu, Jianchun Pan, 2013, Metabolic Brain Disease.

Inhibition of Phosphodiesterase-4 Reverses Aβ-Induced Memory Impairment by Regulation of HPA Axis Related cAMP Signaling

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2018, Front. Aging Neurosci..

The Serotonergic System and Neuroplasticity are Implicated in the Effect of Phytochemicals on Mood and Cognitive Disorders

Ying Xu, W. O. Ogle, Chong Zhang, 2012 .

Phosphodiesterase 2 inhibitor Hcyb1 reverses corticosterone-induced neurotoxicity and depression-like behavior

Xiongwei Zhu, J. O'Donnell, Ying Xu, 2020, Psychopharmacology.

The antidepressant- and anxiolytic-like effects of resveratrol: Involvement of phosphodiesterase-4D inhibition

J. O'Donnell, Ying Xu, Xiaoxin Yin, 2019, Neuropharmacology.

The effect of trans-resveratrol on post-stroke depression via regulation of hypothalamus–pituitary–adrenal axis

Ying Xu, Han-Ting Zhang, Jianchun Pan, 2015, Neuropharmacology.

Antidepressant-like effect of flaxseed secoisolariciresinol diglycoside in ovariectomized mice subjected to unpredictable chronic stress

Rui Wang, Ying Xu, Jianchun Pan, 2012, Metabolic Brain Disease.

Inhibition of PDE2 reverses beta amyloid induced memory impairment through regulation of PKA/PKG-dependent neuro-inflammatory and apoptotic pathways

G. Wang, Ying Xu, Gang Wang, 2017, Scientific Reports.

trans-Resveratrol ameliorates anxiety-like behaviors and fear memory deficits in a rat model of post-traumatic stress disorder

Ying Xu, Jianchun Pan, Gang Wang, 2018, Neuropharmacology.

trans-Resveratrol Ameliorates Stress-Induced Irritable Bowel Syndrome-Like Behaviors by Regulation of Brain-Gut Axis

Ying Xu, J. Si, S. Cui, 2018, Front. Pharmacol..

Protective effects of phosphodiesterase 2 inhibitor on depression- and anxiety-like behaviors: Involvement of antioxidant and anti-apoptotic mechanisms

J. O'Donnell, A. Nadeem, Ying Xu, 2014, Behavioural Brain Research.

The effect of curcumin on the brain-gut axis in rat model of irritable bowel syndrome: involvement of 5-HT-dependent signaling

Ying Xu, Jianchun Pan, Xuefeng Yu, 2014, Metabolic Brain Disease.

Resveratrol Improves Brain-Gut Axis by Regulation of 5-HT-Dependent Signaling in the Rat Model of Irritable Bowel Syndrome

Ying Xu, J. Si, Jing Li, 2019, Front. Cell. Neurosci..

Phosphodiesterases: CNS Functions and Diseases

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2017, Advances in Neurobiology.

Design and functional evaluation of an optically active μ-opioid receptor.

Ying Xu, W. O. Ogle, Y. Jarajapu, 2013, European journal of pharmacology.

Curcumin reverses impaired cognition and neuronal plasticity induced by chronic stress

Ying Xu, W. O. Ogle, Jianchun Pan, 2009, Neuropharmacology.

The effects of curcumin on depressive-like behaviors in mice.

Xue-jun Li, Ying Xu, Yong-He Zhang, 2005, European journal of pharmacology.

Phytochemicals as Antidepressants: The Involvement of Serotonin Receptor Function, Stress Resistance and Neurogenesis

Rui Wang, Ying Xu, 2012 .

Curcumin protects against glutamate excitotoxicity in rat cerebral cortical neurons by increasing brain-derived neurotrophic factor level and activating TrkB

Rui Wang, Xue-jun Li, Yu-Hua Li, 2008, Brain Research.

Antidepressant effects of curcumin in the forced swim test and olfactory bulbectomy models of depression in rats

Xue-jun Li, Ying Xu, Yong-He Zhang, 2005, Pharmacology Biochemistry and Behavior.

The effect of resveratrol on beta amyloid-induced memory impairment involves inhibition of phosphodiesterase-4 related signaling

G. Wang, J. O'Donnell, Ying Xu, 2016, Oncotarget.

Phosphodiesterases in the central nervous system: implications in mood and cognitive disorders.

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2011, Handbook of experimental pharmacology.

The antidepressant-like effect of fisetin involves the serotonergic and noradrenergic system

Ying Xu, L. Zhen, Jianchun Pan, 2012, Behavioural Brain Research.

The Role of Phosphodiesterase-2 in Psychiatric and Neurodegenerative Disorders.

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2017, Advances in neurobiology.

The roles of phosphodiesterase 2 in the central nervous and peripheral systems.

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2014, Current pharmaceutical design.

Novel Therapeutic Targets in Depression and Anxiety: Antioxidants as a Candidate Treatment

J. O'Donnell, Ying Xu, Chuang Wang, 2014, Current neuropharmacology.

Frontiers in Clinical Drug Research - Alzheimer Disorders

K. Jellinger, J. O'Donnell, M. Crespo-Alonso, 2015 .

Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders.

R. F. Campbell, M. Gurney, J. O'Donnell, 2019, Journal of medicinal chemistry.

Memory enhancing effects of BPN14770, an allosteric inhibitor of phosphodiesterase-4D, in wild-type and humanized mice

M. Gurney, J. O'Donnell, R. Salvi, 2018, Neuropsychopharmacology.

Chronic curcumin treatment normalizes depression-like behaviors in mice with mononeuropathy: involvement of supraspinal serotonergic system and GABAA receptor

Ying Xu, Wen-hua Zhou, Xin Zhao, 2014, Psychopharmacology.

Inhibition of phosphodiesterase 2 by Bay 60-7550 decreases ethanol intake and preference in mice

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2018, Psychopharmacology.

Attenuation of ethanol abstinence-induced anxiety- and depressive-like behavior by the phosphodiesterase-4 inhibitor rolipram in rodents

Ying Xu, Han-Ting Zhang, Jian-hui Liang, 2017, Psychopharmacology.

Inhibition of phosphodiesterase 2 reverses impaired cognition and neuronal remodeling caused by chronic stress

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2015, Neurobiology of Aging.

Phosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavioural changes via cGMP/PKG dependent pathway.

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2013, The international journal of neuropsychopharmacology.

Phosphodiesterase-4D Knock-down in the Prefrontal Cortex Alleviates Chronic Unpredictable Stress-Induced Depressive-Like Behaviors and Memory Deficits in Mice

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2015, Scientific Reports.

Effect of chronic unpredictable mild stress on brain–pancreas relative protein in rat brain and pancreas

Lu Tie, Ying Xu, He-ming Yu, 2005, Behavioural Brain Research.

Antidepressant-like effect of trans-resveratrol: Involvement of serotonin and noradrenaline system

Ying Xu, W. O. Ogle, Jianchun Pan, 2010, European Neuropsychopharmacology.

Protection from Amyloid β Peptide–Induced Memory, Biochemical, and Morphological Deficits by a Phosphodiesterase-4D Allosteric Inhibitor

M. Gurney, J. O'Donnell, Ying Xu, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Antidepressant-like effect of trans-resveratrol in chronic stress model: behavioral and neurochemical evidences.

J. O'Donnell, Rui Wang, Ying Xu, 2013, Journal of psychiatric research.

Curcumin reverses the effects of chronic stress on behavior, the HPA axis, BDNF expression and phosphorylation of CREB

Xue-jun Li, Lu Tie, Ying Xu, 2006, Brain Research.

Phosphodiesterase-5 inhibitor sildenafil prevents neuroinflammation, lowers beta-amyloid levels and improves cognitive performance in APP/PS1 transgenic mice

Ying Xu, Qinwen Wang, Zhuoyou Chen, 2013, Behavioural Brain Research.

Curcumin reverses impaired hippocampal neurogenesis and increases serotonin receptor 1A mRNA and brain-derived neurotrophic factor expression in chronically stressed rats

T. Foster, Xue-jun Li, Ying Xu, 2007, Brain Research.

Synergistic antidepressant-like effect of ferulic acid in combination with piperine: involvement of monoaminergic system

Ying Xu, Ruijie Chen, M. Reed, 2015, Metabolic Brain Disease.

Antidepressant-like effects of a novel curcumin derivative J147: Involvement of 5-HT1A receptor

Ying Xu, Ruijie Chen, Jianchun Pan, 2018, Neuropharmacology.

EphB2 Deficiency Induces Depression-Like Behaviors and Memory Impairment: Involvement of NMDA 2B Receptor Dependent Signaling

Ying Xu, V. Luria, L. Zhen, 2018, Front. Pharmacol..

Piperine potentiates the antidepressant-like effect of trans-resveratrol: involvement of monoaminergic system

Ying Xu, Zhuoyou Chen, Jianchun Pan, 2013, Metabolic Brain Disease.

Piperine potentiates the effects of trans-resveratrol on stress-induced depressive-like behavior: involvement of monoaminergic system and cAMP-dependent pathway

Ying Xu, Jianchun Pan, Gang Wang, 2016, Metabolic Brain Disease.

Chronic resveratrol treatment exerts antihyperalgesic effect and corrects co-morbid depressive like behaviors in mice with mononeuropathy: Involvement of serotonergic system

Ying Xu, Wen-hua Zhou, Xin Zhao, 2014, Neuropharmacology.

trans-Resveratrol ameliorates anxiety-like behaviors and neuropathic pain in mouse model of post-traumatic stress disorder

Ying Xu, V. Luria, Han-Ting Zhang, 2020, Journal of psychopharmacology.

Curcumin exerts antinociceptive effects in a mouse model of neuropathic pain: Descending monoamine system and opioid receptors are differentially involved

Zhi-Li Huang, Ying Xu, Chang-Rui Chen, 2012, Neuropharmacology.

Antidepressant-like effect of low molecular proanthocyanidin in mice: Involvement of monoaminergic system

Ying Xu, Ruijie Chen, W. O. Ogle, 2010, Pharmacology Biochemistry and Behavior.

Attenuation of ethanol abstinence-induced anxiety- and depressive-like behavior by the phosphodiesterase-4 inhibitor rolipram in rodents

Ying Xu, Han-Ting Zhang, Jian-hui Liang, 2017, Psychopharmacology.

The antinociceptive effects of ferulic acid on neuropathic pain: involvement of descending monoaminergic system and opioid receptors

G. Wang, Ying Xu, Xianfeng Huang, 2016, Oncotarget.

A Novel PDE4D Inhibitor BPN14770 Reverses Scopolamine-Induced Cognitive Deficits via cAMP/SIRT1/Akt/Bcl-2 Pathway

M. Gurney, J. O'Donnell, Ying Xu, 2020, Frontiers in Cell and Developmental Biology.

Protection from Amyloid b Peptide – Induced Memory, Biochemical, and Morphological Deficits by a Phosphodiesterase-4D Allosteric Inhibitor s

Donnell, M. Gurney, Ying Xu, 2019 .

Comparison of the Pharmacological Profiles of Selective PDE4B and PDE4D Inhibitors in the Central Nervous System

M. Gurney, J. O'Donnell, Ying Xu, 2017, Scientific Reports.

Inhibition of phosphodiesterase 2 reverses gp91phox oxidase-mediated depression- and anxiety-like behavior

Xiongwei Zhu, J. O'Donnell, Ying Xu, 2018, Neuropharmacology.

The analgesic effect of trans-resveratrol is regulated by calcium channels in the hippocampus of mice

G. Wang, Ying Xu, L. Zhen, 2017, Metabolic Brain Disease.

Animal models of depression and neuroplasticity: assessing drug action in relation to behavior and neurogenesis.

J. O'Donnell, Ying Xu, W. O. Ogle, 2012, Methods in molecular biology.

Ferulic acid increases pain threshold and ameliorates depression-like behaviors in reserpine-treated mice: behavioral and neurobiological analyses

J. O'Donnell, Ying Xu, Jianchun Pan, 2013, Metabolic Brain Disease.

Down-regulation of brain-pancreas relative protein in diabetic rats and by high glucose in PC12 cells: prevention by calpain inhibitors.

Xue-jun Li, Lu Tie, Yu-Hua Li, 2008, Journal of pharmacological sciences.

Antidepressant-like effects of ferulic acid: involvement of serotonergic and norepinergic systems

Ying Xu, Jianchun Pan, Xuefeng Yu, 2015, Metabolic Brain Disease.

Evidence for Global Reduction in Brain Cyclic Adenosine Monophosphate Signaling in Depression

J. O'Donnell, Ying Xu, 2012, Biological Psychiatry.

Role of brain-derived neurotrophic factor in the molecular neurobiology of major depressive disorder

Ying Xu, Renyu Liu, Jianxin Li, 2017, Translational perioperative and pain medicine.

Sub-Acute Treatment of Curcumin Derivative J147 Ameliorates Depression-Like Behavior Through 5-HT1A-Mediated cAMP Signaling

Ying Xu, V. Luria, Yindi Sun, 2020, Frontiers in Neuroscience.

Effect size of memory deficits in mice with adult-onset P301L tau expression

Ying Xu, D. Weitzner, M. Reed, 2014, Behavioural Brain Research.

Inhibition of PDE2 reverses beta amyloid induced memory impairment through regulation of PKA/PKG-dependent neuro-inflammatory and apoptotic pathways

G. Wang, Ying Xu, Zhuoyou Chen, 2017, Scientific Reports.

The effect of curcumin on the brain-gut axis in rat model of irritable bowel syndrome: involvement of 5-HT-dependent signaling

Ying Xu, Jianchun Pan, Xuefeng Yu, 2015, Metabolic Brain Disease.

Curcumin prevents corticosterone‐induced neurotoxicity and abnormalities of neuroplasticity via 5‐HT receptor pathway

Ying Xu, E. Boykin, W. O. Ogle, 2011, Journal of neurochemistry.

Memory enhancement induced by PDE2 knockdown in an Alzheimer's disease model of mice

J. O'Donnell, Ying Xu, Han-Ting Zhang, 2016 .

Characterization of 2 Novel Phosphodiesterase 2 Inhibitors Hcyb1 and PF-05180999 on Depression- and Anxiety-Like Behavior

Xiongwei Zhu, W. Wang, C. Zhan, 2023, The international journal of neuropsychopharmacology.