J. Lorenz

发表

Expression of active protein phosphatase 1 inhibitor-1 attenuates chronic beta-agonist-induced cardiac apoptosis

R. Hajjar, G. Fan, Guoli Chen, 2010, Basic Research in Cardiology.

MEK1-ERK2 Signaling Pathway Protects Myocardium From Ischemic Injury In Vivo

P. Doevendans, J. Pouysségur, S. Meloche, 2004, Circulation.

Physiological role of the α1- and α2-isoforms of the Na+-K+-ATPase and biological significance of their cardiac glycoside binding site

J. Lingrel, J. Lorenz, A. Moseley, 2006 .

Physiological role of the alpha1- and alpha2-isoforms of the Na+-K+-ATPase and biological significance of their cardiac glycoside binding site.

J. Lingrel, J. Lorenz, A. Moseley, 2006, American journal of physiology. Regulatory, integrative and comparative physiology.

Synergistic effects of angiotensin and adenosine in the renal microvasculature.

J. Lorenz, J. Schnermann, J. Briggs, 1994, The American journal of physiology.

Sustained in vivo cardiac protection by a rationally designed peptide that causes ɛ protein kinase C translocation

G. Dorn, Guangyu Wu, J. Lorenz, 1999 .

Norepinephrine-mediated calcium signaling is altered in vascular smooth muscle of diabetic rat.

J. Lorenz, R. Cohen, E. Tam, 1997, Cell calcium.

The alpha2-isoform of Na-K-ATPase mediates ouabain-induced hypertension in mice and increased vascular contractility in vitro.

J. Lingrel, J. Lorenz, R. Paul, 2005, American journal of physiology. Heart and circulatory physiology.

A Thrombospondin-Dependent Pathway for a Protective ER Stress Response

B. Aronow, K. Mori, J. Lawler, 2012, Cell.

Ablation of the calpain-targeted site in cardiac myosin binding protein-C is cardioprotective during ischemia-reperfusion injury.

Erik N. Taylor, D. Kass, R. Gilbert, 2019, Journal of molecular and cellular cardiology.

GDF15/MIC-1 Functions As a Protective and Antihypertrophic Factor Released From the Myocardium in Association With SMAD Protein Activation

T. Hewett, J. Molkentin, J. Lorenz, 2006, Circulation research.

Impaired Cardiac Contractility in Mice Lacking Both the AE3 \batchmode \documentclass[fleqn,10pt,legalpaper]{article} \usepackage{amssymb} \usepackage{amsfonts} \usepackage{amsmath} \pagestyle{empty} \begin{document} \(\mathrm{Cl}^{-}{/}\mathrm{HCO}_{3}^{-}\) \end{document} Exchanger and the NKCC1 N

T. Doetschman, M. Ashraf, Yigang Wang, 2008, Journal of Biological Chemistry.

Decreased blood pressure and vascular smooth muscle tone in mice lacking basolateral Na(+)-K(+)-2Cl(-) cotransporter.

J. Lorenz, G. Shull, R. Paul, 2002, American journal of physiology. Heart and circulatory physiology.

Renal effects of uroguanylin and guanylin in vivo.

L. Forte, J. Lorenz, E. Mann, 1999, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Printed in U.S.A. Copyright © 1999 by The Endocrine Society Reduced Blood Pressure and Increased Sensitivity of the Vasculature to Parathyroid Hormone-Related Protein (PTHrP) in Transgenic Mice Overexpressing the PTH/ PTHrP Receptor in Vascular Smooth Mus

T. Clemens, J. Fagin, J. Lorenz, 2022 .

alpha1G-dependent T-type Ca2+ current antagonizes cardiac hypertrophy through a NOS3-dependent mechanism in mice.

S. Houser, H. Nakayama, J. Molkentin, 2009, The Journal of clinical investigation.

Impaired cardiac hypertrophic response in Calcineurin Aβ-deficient mice

J. Molkentin, J. Lorenz, O. Bueno, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Accelerated onset of heart failure in mice during pressure overload with chronically decreased SERCA2 calcium pump activity.

J. Lorenz, G. Shull, T. Kimball, 2004, American journal of physiology. Heart and circulatory physiology.

Physiological Functions of Plasma Membrane and Intracellular Ca2+ Pumps Revealed by Analysis of Null Mutants

J. Lorenz, V. Prasad, G. Shull, 2003, Annals of the New York Academy of Sciences.

Altered dose response to beta-agonists in SERCA1a-expressing hearts ex vivo and in vivo.

S. Huke, I. Grupp, J. Lorenz, 2002, American journal of physiology. Heart and circulatory physiology.

Impaired Cardiac Performance in Heterozygous Mice with a Null Mutation in the Sarco(endo)plasmic Reticulum Ca2+-ATPase Isoform 2 (SERCA2) Gene*

T. Doetschman, J. Lorenz, G. Shull, 1999, The Journal of Biological Chemistry.

Aquaporin 5-deficient mouse lungs are hyperresponsive to cholinergic stimulation

Carissa M Krane, J. Whitsett, J. Lorenz, 2001, Proceedings of the National Academy of Sciences of the United States of America.

In Vivo and in Vitro Analysis of Cardiac Troponin I Phosphorylation*

P. Rosevear, J. Lorenz, J. Robbins, 2005, Journal of Biological Chemistry.

Rescue of cardiac alpha-actin-deficient mice by enteric smooth muscle gamma-actin.

S. Pawlowski, G. Boivin, T. Doetschman, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Rescue of cardiac α-actin-deficient mice by enteric smooth muscle γ-actin

S. Pawlowski, G. Boivin, T. Doetschman, 1997 .

Transgenic Galphaq overexpression induces cardiac contractile failure in mice.

G. Dorn, G. Boivin, S. Liggett, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Low- and high-level transgenic expression of beta2-adrenergic receptors differentially affect cardiac hypertrophy and function in Galphaq-overexpressing mice.

G. Dorn, S. Liggett, W. Koch, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Cardiotrophic Effects of Protein Kinase C ε Analysis by In Vivo Modulation of PKCε Translocation

G. Dorn, Guangyu Wu, J. Lorenz, 2000 .

Cardiotrophic effects of protein kinase C epsilon: analysis by in vivo modulation of PKCepsilon translocation.

G. Dorn, J. Lorenz, D. Mochly‐Rosen, 2000, Circulation research.

Inducible and myocyte-specific inhibition of PKCalpha enhances cardiac contractility and protects against infarction-induced heart failure.

J. Molkentin, J. Lorenz, R. A. Kaiser, 2007, American journal of physiology. Heart and circulatory physiology.

Pharmacologic Inhibition of Pain Response to Incomplete Vascular Occlusion Blunts Cardiovascular Preconditioning Response.

Nathan Robbins, Jack Rubinstein, J. Lorenz, 2021, Cardiovascular toxicology.

Peripheral Nociception Associated With Surgical Incision Elicits Remote Nonischemic Cardioprotection Via Neurogenic Activation of Protein Kinase C Signaling

G. Fan, J. Lorenz, E. Kranias, 2009, Circulation.

Mice Lacking the Basolateral Na-K-2Cl Cotransporter Have Impaired Epithelial Chloride Secretion and Are Profoundly Deaf*

T. Doetschman, J. Lorenz, G. Shull, 1999, The Journal of Biological Chemistry.

Regulatory effects of phospholamban on cardiac function in intact mice.

J. Lorenz, E. Kranias, 1997, American journal of physiology. Heart and circulatory physiology.

Intracellular ATP can regulate afferent arteriolar tone via ATP-sensitive K+ channels in the rabbit.

J. Lorenz, J. Schnermann, J. Briggs, 1992, The Journal of clinical investigation.

End-systolic stress-velocity and pressure-dimension relationships by transthoracic echocardiography in mice.

J. Lorenz, Richard V. Williams, T. Kimball, 1998, American journal of physiology. Heart and circulatory physiology.

Interactions Between Phospholamban and &bgr;-Adrenergic Drive May Lead to Cardiomyopathy and Early Mortality

G. Dorn, S. Liggett, B. Hoit, 2001, Circulation.

Renal and intestinal transport defects in Slc26a6-null mice.

J. Lorenz, P. Aronson, Tong Wang, 2005, American journal of physiology. Cell physiology.

Kidney and Intestine Transport Defects in Slc 26 a 6 Null Mice

J. Lorenz, P. Aronson, Tong Wang, 2004 .

Renal salt wasting in mice lacking NHE3 Na+/H+ exchanger but not in mice lacking NHE2.

J. Lorenz, G. Shull, P. Schultheis, 2001, American journal of physiology. Renal physiology.

The afferent arteriole--the target for macula densa-generated signals.

J. Lorenz, J. Schnermann, J. Briggs, 1991, Kidney international. Supplement.

hypertension using a modified two-kidney , one-clip approach in mice is not dependent on the 1 or 2 NaK-ATPase ouabain-binding site

J. Lingrel, J. Lorenz, V. Prasad, 2011 .

Renovascular hypertension using a modified two-kidney, one-clip approach in mice is not dependent on the α1 or α2 Na-K-ATPase ouabain-binding site.

J. Lingrel, J. Lorenz, V. Prasad, 2011, American journal of physiology. Renal physiology.

The non-diuretic hypotensive effects of thiazides are enhanced during volume depletion states

Jack Rubinstein, J. Lorenz, Min Jiang, 2017, PloS one.

Pharmacological and Activated Fibroblast Targeting of Gβγ-GRK2 After Myocardial Ischemia Attenuates Heart Failure Progression.

J. Molkentin, J. Lorenz, Íñigo Valiente-Alandí, 2017, Journal of the American College of Cardiology.

Direct vasoconstriction as a possible cause for amphotericin B-induced nephrotoxicity in rats.

W. R. Campbell, J. Lorenz, J. Schnermann, 1991, The Journal of clinical investigation.

Mice expressing ouabain‐sensitive α1 Na,K‐ATPase have increased susceptibility to pressure overload‐induced cardiac hypertrophy

J. Lingrel, J. Lorenz, A. Wansapura, 2009, American journal of physiology. Heart and circulatory physiology.

Fibroblast growth factor-2 mediates pressure-induced hypertrophic response.

S. Pawlowski, T. Doetschman, J. Lorenz, 1999, The Journal of clinical investigation.

Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts: critical role for expression level.

G. Dorn, S. Liggett, J. Lorenz, 2000, Circulation.

Hearts : Critical Role for Expression Level-Adrenergic Receptor Overexpression in Mouse 2 β Early and Delayed Consequences of Print

G. Dorn, S. Liggett, J. Lorenz, 2000 .

Protein Kinase C (cid:1) , but Not PKC (cid:2) or PKC (cid:3) , Regulates Contractility and Heart Failure Susceptibility Implications for Ruboxistaurin as a Novel Therapeutic Approach

S. Houser, J. Molkentin, J. Lorenz, 2009 .

Probenecid: novel use as a non-injurious positive inotrope acting via cardiac TRPV2 stimulation.

Sheryl E. Koch, Nathan Robbins, Jack Rubinstein, 2012, Journal of molecular and cellular cardiology.

Myocardial signaling defects and impaired cardiac function of a human beta 2-adrenergic receptor polymorphism expressed in transgenic mice.

S. Green, S. Liggett, Jamal Adel Turki, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Extracellular Signal-Regulated Kinases 1 and 2 Regulate the Balance Between Eccentric and Concentric Cardiac Growth

S. Meloche, J. Molkentin, W. Zimmermann, 2011, Circulation research.

Sustained in vivo cardiac protection by a rationally designed peptide that causes epsilon protein kinase C translocation.

G. Dorn, J. Lorenz, D. Mochly‐Rosen, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Fast skeletal myosin-binding protein-C regulates fast skeletal muscle contraction

T. Irving, J. Lorenz, S. Sadayappan, 2021, Proceedings of the National Academy of Sciences.

Expression of R120G–αB-Crystallin Causes Aberrant Desmin and αB-Crystallin Aggregation and Cardiomyopathy in Mice

T. Hewett, J. Lorenz, A. Gerdes, 2001 .

Expression of R120G-alphaB-crystallin causes aberrant desmin and alphaB-crystallin aggregation and cardiomyopathy in mice.

T. Hewett, J. Lorenz, A. Gerdes, 2001, Circulation research.

Loss of the AE3 anion exchanger in a hypertrophic cardiomyopathy model causes rapid decompensation and heart failure.

S. Alper, J. Lorenz, V. Prasad, 2011, Journal of molecular and cellular cardiology.

Transient receptor potential vanilloid 2 function regulates cardiac hypertrophy via stretch-induced activation

Sheryl E. Koch, Nathan Robbins, Jack Rubinstein, 2017, Journal of hypertension.

Overexpression of α1B-adrenergic receptor induces left ventricular dysfunction in the absence of hypertrophy.

G. Boivin, R. Walsh, I. Grupp, 1998, American journal of physiology. Heart and circulatory physiology.

Overexpression of alpha1B-adrenergic receptor induces left ventricular dysfunction in the absence of hypertrophy.

G. Boivin, R. Walsh, I. Grupp, 1998, The American journal of physiology.

Cardiac Specific Overexpression of Transglutaminase II (Gh) Results in a Unique Hypertrophy Phenotype Independent of Phospholipase C Activation*

G. Dorn, S. Liggett, K. Small, 1999, The Journal of Biological Chemistry.

Effect of adenosine1-receptor blockade on renin release from rabbit isolated perfused juxtaglomerular apparatus.

J. Lorenz, J. Schnermann, J. Briggs, 1990, The Journal of clinical investigation.

Placental Growth Factor Regulates Cardiac Adaptation and Hypertrophy Through a Paracrine Mechanism

P. Carmeliet, J. Molkentin, J. Lorenz, 2011, Circulation research.

Cardiac myosin binding protein c phosphorylation is cardioprotective

J. Seidman, C. Seidman, J. Lorenz, 2006, Proceedings of the National Academy of Sciences.

Cardiac Myosin Binding Protein-C Phosphorylation in a &bgr;-Myosin Heavy Chain Background

J. Molkentin, J. Lorenz, S. Sadayappan, 2009, Circulation.

Role of the acidic N′ region of cardiac troponin I in regulating myocardial function

P. Rosevear, J. Lorenz, S. Sadayappan, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Knockout of the Na,K-ATPase α2-isoform in cardiac myocytes delays pressure overload-induced cardiac dysfunction.

J. Lingrel, J. Lorenz, M. Nieman, 2013, American journal of physiology. Heart and circulatory physiology.

End-systolic stress-velocity and pressure-dimension relationships by transthoracic echocardiography in mice.

J. Lorenz, T. Kimball, P. Khoury, 1998, The American journal of physiology.

Heart-specific Deletion of CnB1 Reveals Multiple Mechanisms Whereby Calcineurin Regulates Cardiac Growth and Function*♦

J. Molkentin, J. Lorenz, M. Maillet, 2009, The Journal of Biological Chemistry.

Altering the receptor-effector ratio by transgenic overexpression of type V adenylyl cyclase: enhanced basal catalytic activity and function without increased cardiomyocyte beta-adrenergic signalling.

G. Dorn, S. Liggett, J. Lorenz, 1999, Biochemistry.

Analysis of Myosin Heavy Chain Functionality in the Heart*

T. Hewett, N. Alpert, S. Helmke, 2003, The Journal of Biological Chemistry.

Tranilast Blunts the Hypertrophic and Fibrotic Response to Increased Afterload Independent of Cardiomyocyte Transient Receptor Potential Vanilloid 2 Channels

Sheryl E. Koch, Nathan Robbins, Jack Rubinstein, 2018, Journal of cardiovascular pharmacology.

Renal tubular chloride and renin release.

W. Welch, J. Lorenz, T. Kotchen, 1987, The Journal of laboratory and clinical medicine.

Functional dissection of myosin binding protein C phosphorylation.

J. Lorenz, M. Gupta, J. Robbins, 2013, Journal of molecular and cellular cardiology.

Micropuncture analysis of single-nephron function in NHE3-deficient mice.

J. Lorenz, J. Schnermann, G. Shull, 1999, American journal of physiology. Renal physiology.

Profiling of renal tubule Na+ transporter abundances in NHE3 and NCC null mice using targeted proteomics

M. Knepper, J. Lorenz, H. Brooks, 2001, The Journal of physiology.

Dependence of Ca2+ channel currents on endogenous and exogenous sources of ATP in portal vein smooth muscle.

J. Lorenz, R. Paul, 1997, The American journal of physiology.

Hypotension in NKCC1 null mice: role of the kidneys.

M. Knepper, J. Lorenz, G. Shull, 2006, American journal of physiology. Renal physiology.

Increased sensitivity to K+ deprivation in colonic H,K-ATPase-deficient mice.

T. Doetschman, P. Meneton, J. Lorenz, 1998, The Journal of clinical investigation.

Smooth muscle-targeted overexpression of insulin-like growth factor I results in enhanced vascular contractility.

J. Fagin, J. Lorenz, R. Paul, 2001, Endocrinology.

Chronic renal failure in a mouse model of human adenine phosphoribosyltransferase deficiency.

G. Boivin, J. Tischfield, J. Lorenz, 1998, American journal of physiology. Renal physiology.

Considerations for the evaluation of renal function in genetically engineered mice

J. Lorenz, 2001, Current opinion in nephrology and hypertension.

Renal function in NHE3-deficient mice with transgenic rescue of small intestinal absorptive defect.

J. Lorenz, G. Shull, J. Neumann, 2003, American journal of physiology. Renal physiology.

Measurement of intraventricular pressure and cardiac performance in the intact closed-chest anesthetized mouse.

J. Lorenz, J. Robbins, 1997, The American journal of physiology.

Unrestrained p38 MAPK Activation in Dusp1/4 Double-Null Mice Induces Cardiomyopathy

R. Willette, J. Molkentin, J. Lorenz, 2013, Circulation research.

A simple, nonradioactive method for evaluating single-nephron filtration rate using FITC-inulin.

E. Gruenstein, J. Lorenz, 1999, American journal of physiology. Renal physiology.

Effects of chlorpropamide on loop of Henle function and plasma renin.

W. Welch, J. Lorenz, T. Kotchen, 1986, Kidney international.

Transgenic overexpression of cardiac actin in the mouse heart suggests coregulation of cardiac, skeletal and vascular actin expression

J. Lorenz, K. Bove, J. Lessard, 2004, Transgenic Research.

Mouse Model of Desmin-Related Cardiomyopathy

G. Dorn, J. Lorenz, A. Gerdes, 2001, Circulation.

Clearance studies in genetically altered mice.

J. Lorenz, W. Noonan, 2003, Methods in molecular medicine.

An internal domain of beta-tropomyosin increases myofilament Ca(2+) sensitivity.

G. Boivin, S. Liggett, M. Ashraf, 2009, American journal of physiology. Heart and circulatory physiology.

Micropuncture of the kidney: a primer on techniques.

J. Lorenz, 2012, Comprehensive Physiology.

Phenotype Resembling Gitelman’s Syndrome in Mice Lacking the Apical Na+-Cl− Cotransporter of the Distal Convoluted Tubule*

T. Doetschman, P. Meneton, J. Lorenz, 1998, The Journal of Biological Chemistry.

The highly conserved cardiac glycoside binding site of Na,K-ATPase plays a role in blood pressure regulation.

J. Lingrel, J. Lorenz, Iva Dostanic-Larson, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Targeted overexpression of parathyroid hormone-related protein (PTHrP) to vascular smooth muscle in transgenic mice lowers blood pressure and alters vascular contractility.

T. Clemens, D. Witte, J. Fagin, 1999, Endocrinology.

Cardiac Myosin Binding Protein-C Phosphorylation in a (cid:1) -Myosin Heavy Chain Background Molecular Cardiology

J. Molkentin, J. Lorenz, S. Sadayappan, 2009 .

Genetic Profiling Reveals Global Changes in Multiple Biological Pathways in the Hearts of Na, K-ATPase Alpha 1 Isoform Haploinsufficient Mice

B. Aronow, J. Lingrel, J. Lorenz, 2005, Cellular Physiology and Biochemistry.

The α2 Isoform of Na,K-ATPase Mediates Ouabain-induced Cardiac Inotropy in Mice*

I. Grupp, J. Lingrel, J. Lorenz, 2003, Journal of Biological Chemistry.

Renin release from isolated juxtaglomerular apparatus depends on macula densa chloride transport.

J. Lorenz, J. Schnermann, J. Briggs, 1991, The American journal of physiology.

Role of the acidic N (cid:1) region of cardiac troponin I in regulating myocardial function

P. Rosevear, J. Lorenz, S. Sadayappan, 2008 .

Transgenic mice expressing Na+-K+-ATPase in smooth muscle decreases blood pressure.

Tracy J. Pritchard, J. Lorenz, R. Paul, 2007, American journal of physiology. Heart and circulatory physiology.

Vascular dysfunction in S1P2 sphingosine 1-phosphate receptor knockout mice.

J. Lorenz, R. Paul, L. Arend, 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

Altered renal hemodynamics in mice overexpressing the parathyroid hormone (PTH)/PTH-related peptide type 1 receptor in smooth muscle.

T. Clemens, J. Lorenz, W. Noonan, 2003, Endocrinology.

ACTH-induced hypertension is dependent on the ouabain-binding site of the alpha2-Na+-K+-ATPase subunit.

J. Lingrel, J. Lorenz, J. Schnetzer, 2008, American journal of physiology. Heart and circulatory physiology.

Knockout of the Na,K-ATPase α₂-isoform in the cardiovascular system does not alter basal blood pressure but prevents ACTH-induced hypertension.

J. Lingrel, J. Lorenz, J. Neumann, 2011, American journal of physiology. Heart and circulatory physiology.

Ouabain-Sensitive alpha1 Na,K-ATPase enhances natriuretic response to saline load.

J. Lingrel, J. Lorenz, B. Kaul, 2008, Journal of the American Society of Nephrology : JASN.

Ouabain-Sensitive (cid:1) 1 Na,K-ATPase Enhances Natriuretic Response to Saline Load

J. Lingrel, J. Lorenz, B. Kaul, 2008 .

Ouabain inhibits tubuloglomerular feedback in mutant mice with ouabain-sensitive alpha1 Na,K-ATPase.

J. Lingrel, J. Lorenz, G. Shull, 2006, Journal of the American Society of Nephrology : JASN.

Tropomyosin 3 expression leads to hypercontractility and attenuates myofilament length-dependent Ca(2+) activation.

G. Boivin, T. Irving, I. Grupp, 2002, American journal of physiology. Heart and circulatory physiology.

Evolution of the mdx mouse cardiomyopathy: physiological and morphological findings

B. Wong, J. Lorenz, H. Hahn, 2004, Neuromuscular Disorders.

SERCA2 Haploinsufficiency in a Mouse Model of Darier Disease Causes a Selective Predisposition to Heart Failure

Wei Huang, Yigang Wang, J. Lorenz, 2015, BioMed research international.

Ablation of plasma membrane Ca(2+)-ATPase isoform 4 prevents development of hypertrophy in a model of hypertrophic cardiomyopathy.

Jack Rubinstein, J. Lorenz, V. Prasad, 2014, Journal of molecular and cellular cardiology.

Vascular dysfunction in S 1 P 2 sphingosine 1-phosphate receptor knockout mice

J. Lorenz, L. Arend, A. MacLennan, 2006 .

Induction of water diuresis by endothelin in rats.

J. Keiser, J. Lorenz, J. Schnermann, 1992, The American journal of physiology.

Impaired Renal NaCl Absorption in Mice Lacking the ROMK Potassium Channel, a Model for Type II Bartter's Syndrome*

T. Doetschman, J. Lorenz, G. Shull, 2002, The Journal of Biological Chemistry.

Transgenic mice with cardiac-specific over-expression of MLK7 have increased mortality when exposed to chronic beta-adrenergic stimulation.

P. Iversen, Xiaohong Yu, J. Lorenz, 2004, Journal of molecular and cellular cardiology.

Increased renal renin content in mice lacking the Na+/H+ exchanger NHE2.

Elliott J. Meer, J. Lorenz, R. Chambrey, 2008, American journal of physiology. Renal physiology.

The macula densa mechanism for control of renin secretion.

J. Lorenz, J. Briggs, S. Greenberg, 1993, Seminars in nephrology.

Blood pressure maintenance in NHE3-deficient mice with transgenic expression of NHE3 in small intestine.

J. Lorenz, V. Prasad, G. Shull, 2005, American journal of physiology. Regulatory, integrative and comparative physiology.

The alpha2 isoform of Na,K-ATPase mediates ouabain-induced cardiac inotropy in mice.

I. Grupp, J. Lingrel, J. Lorenz, 2003, The Journal of biological chemistry.

Colonic anion secretory defects and metabolic acidosis in mice lacking the NBC1 Na+/HCO3- cotransporter.

T. Doetschman, J. Lorenz, V. Prasad, 2007, The Journal of biological chemistry.

An internal domain of -tropomyosin increases myofilament Ca sensitivity

G. Boivin, S. Liggett, M. Ashraf, 2009 .

Marinobufagenin enhances cardiac contractility in mice with ouabain-sensitive alpha1 Na+-K+-ATPase.

J. Lingrel, J. Lorenz, Zijian Xie, 2008, American journal of physiology. Heart and circulatory physiology.

Marinobufagenin enhances cardiac contractility in mice with ouabain-sensitive (cid:1) Na -ATPase

J. Lingrel, J. Lorenz, Zijian Xie, 2009 .

Renal and intestinal absorptive defects in mice lacking the NHE3 Na +/H+ exchanger

G. Giebisch, T. Doetschman, P. Meneton, 1998, Nature Genetics.

Regulation of Ca2+ Channels in Vascular Smooth Muscle Cells by Cyclic Nucleotides and by G-Protein Gating

J. Lorenz, N. Sperelakis, Z. Xiong, 1994 .

Fast Na+ Current and Ca2+ Currents in Smooth Muscles

J. Lorenz, N. Sperelakis, Y. Ohya, 1993 .

The α1 Isoform of Na,K-ATPase Regulates Cardiac Contractility and Functionally Interacts and Co-localizes with the Na/Ca Exchanger in Heart*

J. Lingrel, J. Lorenz, I. Dostanic, 2004, Journal of Biological Chemistry.

glycoside binding site -ATPase and biological significance of their cardiac + -K

J. Lingrel, J. Lorenz, J. Neumann, 2016 .

Contribution of the basolateral isoform of the Na-K-2Cl- cotransporter (NKCC1/BSC2) to renin secretion.

J. Lorenz, J. Schnermann, J. Briggs, 2005, American journal of physiology. Renal physiology.

Chloride channel function is linked to epithelium-dependent airway relaxation.

J. Lorenz, R. Paul, C. Fortner, 2001, American journal of physiology. Lung cellular and molecular physiology.

Novel role of transient receptor potential vanilloid 2 in the regulation of cardiac performance.

Nathan Robbins, Jack Rubinstein, J. Lorenz, 2014, American journal of physiology. Heart and circulatory physiology.

PKC-α regulates cardiac contractility and propensity toward heart failure

T. Hewett, A. Nairn, J. Bibb, 2004, Nature Medicine.

CLIC5 mutant mice are resistant to diet-induced obesity and exhibit gastric hemorrhaging and increased susceptibility to torpor.

Vikram Prasad, P. Tso, J. Lorenz, 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

Interaction between transcellular and paracellular water transport pathways through Aquaporin 5 and the tight junction complex

G. Boivin, J. Lorenz, A. Hand, 2007, Proceedings of the National Academy of Sciences.

Biochemical and Mechanical Dysfunction in a Mouse Model of Desmin-Related Myopathy

Richard T. Lee, D. Kass, J. Lammerding, 2009, Circulation research.

Cardiac Dysfunction in the Sigma 1 Receptor Knockout Mouse Associated With Impaired Mitochondrial Dynamics and Bioenergetics

M. Bhuiyan, J. Lorenz, S. Alam, 2018, Journal of the American Heart Association.

The IP3 Receptor Regulates Cardiac Hypertrophy in Response to Select Stimuli

K. Mikoshiba, D. Bers, L. Blatter, 2010, Circulation research.

Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy

G. Dorn, B. Aronow, Guangyu Wu, 2002, Nature Medicine.

Defective Endothelium-dependent Relaxation of Vascular Smooth Muscle and Endothelial Cell Ca2+ Signaling in Mice Lacking Sarco(endo)plasmic Reticulum Ca2+-ATPase Isoform 3*

T. Doetschman, J. Lorenz, G. Shull, 1997, The Journal of Biological Chemistry.

Fibroblast growth factor 2 control of vascular tone

S. Pawlowski, M. Yin, G. Boivin, 1998, Nature Medicine.

A role for Smad6 in development and homeostasis of the cardiovascular system

M. Gimbrone, J. Lorenz, D. Huszar, 2000, Nature Genetics.

Inhibiting Fibronectin Attenuates Fibrosis and Improves Cardiac Function in a Model of Heart Failure

J. Molkentin, J. Lorenz, S. Potter, 2018, Circulation.

Abnormal Cardiac Structure and Function in Mice Expressing Nonphosphorylatable Cardiac Regulatory Myosin Light Chain 2*

J. Lorenz, J. Fewell, J. Robbins, 1999, The Journal of Biological Chemistry.

RNA SEQ Analysis Indicates that the AE3 Cl−/HCO3− Exchanger Contributes to Active Transport-Mediated CO2 Disposal in Heart

M. Medvedovic, J. Lorenz, G. Shull, 2017, Scientific Reports.

NBCe1 Na+-HCO3- cotransporter ablation causes reduced apoptosis following cardiac ischemia-reperfusion injury in vivo

M. Medvedovic, Wei Huang, Yigang Wang, 2018, World journal of cardiology.

Loss of the AE3 Cl−/HCO−3 exchanger in mice affects rate-dependent inotropy and stress-related AKT signaling in heart

J. Lorenz, V. Prasad, G. Shull, 2013, Front. Physiol..

Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins.

C. Berul, H. Wakimoto, M. Donoghue, 2003, Journal of molecular and cellular cardiology.

Vasomotor effects of purinergic agonists in isolated rabbit afferent arterioles.

J. Lorenz, J. Schnermann, J. Briggs, 1992, The American journal of physiology.

Effect of Na and Cl infusion on loop function and plasma renin activity in rats.

J. Lorenz, T. Kotchen, C. Ott, 1990, The American journal of physiology.

Autonomic dysfunction following traumatic brain injury: translational insights.

J. Lorenz, J. McGuire, Laura B. Ngwenya, 2019, Neurosurgical focus.

Effect of salt deprivation on blood pressure in rats.

W. Welch, J. Lorenz, T. Kotchen, 1989, The American journal of physiology.

Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy.

V. Schmithorst, S. Holland, P. Rakic, 2006, The American journal of pathology.

A Critical Function for Ser-282 in Cardiac Myosin Binding Protein-C Phosphorylation and Cardiac Function

D. Bers, J. Molkentin, J. Lorenz, 2011, Circulation research.

Nix-Mediated Apoptosis Links Myocardial Fibrosis, Cardiac Remodeling, and Hypertrophy Decompensation

G. Dorn, J. Wansapura, J. Lorenz, 2008, Circulation.

In vivo definition of cardiac myosin-binding protein C’s critical interactions with myosin

M. Bhuiyan, J. Lorenz, Patrick M. McLendon, 2016, Pflügers Archiv - European Journal of Physiology.

Mice without myoglobin

Daniel J. Garry, Robert W. Grange, R. Grange, 1998, Nature.

Dioxin exposure is an environmental risk factor for ischemic heart disease

Bin Wang, Alvaro Puga, D. Nebert, 2007, Cardiovascular Toxicology.

A practical guide to evaluating cardiovascular, renal, and pulmonary function in mice.

J. Lorenz, John N Lorenz, 2002, American journal of physiology. Regulatory, integrative and comparative physiology.

Macula densa control of renin secretion.

J. Lorenz, J. Schnermann, J. Briggs, 1991, Renal physiology and biochemistry.

Micropuncture analysis of single-nephron function in NHE3-deficient mice.

J. Lorenz, J. Schnermann, G. Shull, 1999, American Journal of Physiology.

Characterization of the macula densa stimulus for renin secretion.

J. Lorenz, J. Schnermann, J. Briggs, 1990, The American journal of physiology.

Chronic renal failure in a mouse model of human adenine phosphoribosyltransferase deficiency.

G. Boivin, J. Tischfield, J. Lorenz, 1998, The American journal of physiology.

Uroguanylin knockout mice have increased blood pressure and impaired natriuretic response to enteral NaCl load.

J. Lorenz, L. Gawenis, Mitchell Cohen, 2003, The Journal of clinical investigation.

Low- and high-level transgenic expression of β2-adrenergic receptors differentially affect cardiac hypertrophy and function in Gαq-overexpressing mice

G. Dorn, S. Liggett, W. Koch, 1999 .

Enhancement of Cardiac Function and Suppression of Heart Failure Progression By Inhibition of Protein Phosphatase 1

Andrew N. Carr, E. Heist, J. Guerrero, 2005, Circulation research.

PKC-alpha regulates cardiac contractility and propensity toward heart failure.

T. Hewett, A. Nairn, J. Bibb, 2004, Nature medicine.

Effects of adenosine and angiotensin on macula densa-stimulated renin secretion.

J. Lorenz, J. Schnermann, J. Briggs, 1993, The American journal of physiology.

Sickle cell anemia mice develop a unique cardiomyopathy with restrictive physiology

B. Aronow, J. Towbin, J. Wansapura, 2016, Proceedings of the National Academy of Sciences.

Human antigen R as a therapeutic target in pathological cardiac hypertrophy.

Nathan Robbins, Jack Rubinstein, J. Lorenz, 2019, JCI insight.

Transgenic Gαq overexpression induces cardiac contractile failure in mice

G. Dorn, G. Boivin, S. Liggett, 1997 .

Faculty Opinions recommendation of Na,K-ATPase activity modulates Src activation: a role for ATP/ADP ratio.

J. Lorenz, 2012 .

Cardiac compartment-specific overexpression of a modified retinoic acid receptor produces dilated cardiomyopathy and congestive heart failure in transgenic mice.

T. Hewett, M. Kirby, J. Lorenz, 1997, The Journal of clinical investigation.

Effect of prostaglandin synthesis inhibition on macula densa-stimulated renin secretion.

J. Lorenz, J. Schnermann, J. Briggs, 1993, The American journal of physiology.

Regulation of calcium channel current in A7r5 vascular smooth muscle cells by cyclic nucleotides.

J. Lorenz, N. Sperelakis, D. Bielefeld, 1994, The American journal of physiology.

Constitutive phosphorylation of inhibitor-1 at Ser67 and Thr75 depresses calcium cycling in cardiomyocytes and leads to remodeling upon aging

Jack Rubinstein, J. Qian, Wen-Feng Cai, 2012, Basic Research in Cardiology.

Protein Kinase Cα, but Not PKCβ or PKCγ, Regulates Contractility and Heart Failure Susceptibility: Implications for Ruboxistaurin as a Novel Therapeutic Approach

S. Houser, J. Molkentin, J. Lorenz, 2009, Circulation research.

In vivo definition of cardiac myosin-binding protein C’s critical interactions with myosin

M. Bhuiyan, J. Lorenz, Patrick M. McLendon, 2016, Pflügers Archiv - European Journal of Physiology.

Regulatory effects of phospholamban on cardiac function in intact mice.

J. Lorenz, E. Kranias, 1997, The American journal of physiology.

Targeted Inhibition of Ca2+/Calmodulin-dependent Protein Kinase II in Cardiac Longitudinal Sarcoplasmic Reticulum Results in Decreased Phospholamban Phosphorylation at Threonine 17*

J. Lorenz, M. Kaetzel, J. Dedman, 2003, Journal of Biological Chemistry.

Dissociation between plasma renin and plasma aldosterone induced by dietary glycine hydrochloride.

J. Lorenz, T. Kotchen, C. Ott, 1988, The American journal of physiology.

Loss of NHE1 activity leads to reduced oxidative stress in heart and mitigates high-fat diet-induced myocardial stress.

Yigang Wang, J. Lorenz, V. Prasad, 2013, Journal of molecular and cellular cardiology.

DOCA-salt hypertension does not require the ouabain-sensitive binding site of the α2 Na,K-ATPase.

J. Lingrel, J. Lorenz, Elizabeth L. Loreaux, 2012, American journal of hypertension.

Abnormal Calcium Cycling and Cardiac Arrhythmias Associated With the Human Ser96Ala Genetic Variant of Histidine‐Rich Calcium‐Binding Protein

D. H. Kim, K. Jones, C. Cho, 2013, Journal of the American Heart Association.

Structural and functional implications of the phospholamban hinge domain: impaired SR Ca2+ uptake as a primary cause of heart failure.

Andrew N. Carr, A. Annila, B. Hoit, 2002, Cardiovascular research.

Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility.

M. Zilliox, T. Irving, R. Gilbert, 2021, Journal of molecular and cellular cardiology.

Chymase: the other ACE?

J. Lorenz, 2010, American journal of physiology. Renal physiology.

Overexpression of miR-223 Tips the Balance of Pro- and Anti-hypertrophic Signaling Cascades toward Physiologic Cardiac Hypertrophy*

Xiaohong Wang, Yutian Li, Wei Huang, 2016, The Journal of Biological Chemistry.

Marinobufagenin enhances cardiac contractility in mice with ouabain‐sensitive α1 Na,K‐ATPase (NKA)

J. Lingrel, J. Lorenz, O. Fedorova, 2008 .