P. Hurn

发表

Cyclic Adenosine Monophosphate Response Element-Binding Protein Phosphorylation and Neuroprotection by 4-Phenyl-1-(4-Phenylbutyl) Piperidine (PPBP)

Sufang Yang, N. Alkayed, P. Hurn, 2009, Anesthesia and analgesia.

Sex, Sex Steroids, and Brain Injury

P. Hurn, P. Herson, I. Koerner, 2009, Seminars in reproductive medicine.

Aromatase Cytochrome P450 and Extragonadal Estrogen Play a Role in Ischemic Neuroprotection

L. McCullough, P. Hurn, E. Simpson, 2003, The Journal of Neuroscience.

Estradiol and G1 Reduce Infarct Size and Improve Immunosuppression after Experimental Stroke

Bing Zhang, P. Hurn, K. Akiyoshi, 2010, The Journal of Immunology.

Stroke in Estrogen Receptor-α–Deficient Mice

Randy J. Nelson, Shozo Goto, Nabil J. Alkayed, 2000 .

Rapid three‐dimensional diffusion MRI facilitates the study of acute stroke in mice

P. V. van Zijl, R. Traystman, P. Hurn, 2001, Magnetic resonance in medicine.

Inhalational Anesthetics as Neuroprotectants or Chemical Preconditioning Agents in Ischemic Brain

P. Hurn, J. Kirsch, S. Murphy, 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Postischemic recovery rate of cerebral ATP, phosphocreatine, pH, and evoked potentials.

R. Koehler, R. Traystman, P. Hurn, 1989, The American journal of physiology.

Estrogen and selective estrogen receptor modulators

Stephanie Murphy, Louise McCullough, L. McCullough, 2003, Endocrine.

An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain

Ole Petter Ottersen, Peter Agre, Richard J Traystman, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Exploring a need for improved preclinical models of post-stroke depression

T. Schallert, P. Hurn, N. Mittal, 2016, Neural regeneration research.

Gender and the injured brain.

P. Hurn, P. Herson, 2010, Progress in brain research.

Estradiol Attenuates Neuroprotective Benefits of Isoflurane Preconditioning in Ischemic Mouse Brain

P. Hurn, S. Murphy, Lan-hui Wang, 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Gender-Specific Response to Isoflurane Preconditioning in Focal Cerebral Ischemia

P. Hurn, Jian Cheng, S. Murphy, 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Postischemic Angiogenic Factor Expression in Stroke-Prone Rats

R. Traystman, Michael M. Wang, P. Hurn, 2002, Experimental Neurology.

Hypothermic cerebral reperfusion and recovery from ischemia.

R. Traystman, P. Hurn, J. Kirsch, 1991, The American journal of physiology.

Effects of Androgens on Early Post-ischemic Neurogenesis in Mice

A. Brambrink, M. Grafe, P. Hurn, 2013, Translational Stroke Research.

Splenic Atrophy in Experimental Stroke Is Accompanied by Increased Regulatory T Cells and Circulating Macrophages1

P. Hurn, A. Vandenbark, H. Offner, 2006, The Journal of Immunology.

Preeclampsia: Association With Posterior Reversible Encephalopathy Syndrome and Stroke

T. Rundek, C. Bushnell, P. Hurn, 2018, Stroke.

Regulatory B Cells Limit CNS Inflammation and Neurologic Deficits in Murine Experimental Stroke

P. Hurn, K. Akiyoshi, A. Vandenbark, 2011, The Journal of Neuroscience.

Chronic behavioral testing after focal ischemia in the mouse: functional recovery and the effects of gender

L. McCullough, P. Hurn, A. Devries, 2004, Experimental Neurology.

Effect of experimental stroke on peripheral immunity: CNS ischemia induces profound immunosuppression

P. Hurn, A. Vandenbark, H. Offner, 2009, Neuroscience.

A Novel Hypothesis: Regulatory B Lymphocytes Shape Outcome from Experimental Stroke

P. Hurn, H. Offner, 2012, Translational Stroke Research.

Role of P450 Aromatase in Sex-Specific Astrocytic Cell Death

N. Alkayed, P. Hurn, C. Roselli, 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Poly(ADP-ribose) (PAR) polymer is a death signal

R. Koehler, T. Dawson, V. Dawson, 2006, Proceedings of the National Academy of Sciences.

17beta-estradiol reduces stroke injury in estrogen-deficient female animals.

B. Crain, R. Traystman, E. London, 1999, Stroke.

Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injury

F. Tortella, R. Traystman, M. Yudkoff, 1999, Nature Medicine.

Mechanisms of gender-linked ischemic brain injury.

N. Alkayed, P. Hurn, S. Dziennis, 2009, Restorative neurology and neuroscience.

Future Perspectives in Stroke Management

C. Anderson, G. Kwakkel, M. Dichgans, 2015 .

Estradiol after Cardiac Arrest and Cardiopulmonary Resuscitation is Neuroprotective and Mediated through Estrogen Receptor-β

R. Traystman, R. Noppens, M. Grafe, 2009, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Therapy with recombinant T-cell receptor ligand reduces infarct size and infiltrating inflammatory cells in brain after middle cerebral artery occlusion in mice

P. Hurn, K. Akiyoshi, A. Vandenbark, 2011, Metabolic Brain Disease.

sigma(1)-receptor ligand 4-phenyl-1-(4-phenylbutyl)-piperidine affords neuroprotection from focal ischemia with prolonged reperfusion.

R. Traystman, E. London, P. Hurn, 2000, Stroke.

Cognitive deficits after focal cerebral ischemia in mice.

B. Crain, R. Traystman, P. Hurn, 2000, Stroke.

Focal Ischemia With Prolonged Reperfusion-Receptor Ligand 4-Phenyl-1-( 4-Phenylbutyl )-Piperidine Affords Neuroprotection From 1 σ

R. Traystman, E. London, P. Hurn, 2000 .

Recombinant T Cell Receptor Ligand Treats Experimental Stroke

Bing Zhang, M. Grafe, P. Hurn, 2009, Stroke.

Isolation of Cells From the Spleen , Thymus , and Blood

Bing Zhang, M. Grafe, P. Hurn, 2009 .

Hypertonic Saline Ameliorates Cerebral Edema Associated With Experimental Brain Tumor

R. Traystman, P. Hurn, H. Brem, 2002, Journal of neurosurgical anesthesiology.

Global brain water increases after experimental focal cerebral ischemia: effect of hypertonic saline.

R. Traystman, P. Hurn, A. Bhardwaj, 2002, Critical care medicine.

Estradiol Regulates Angiopoietin-1 mRNA Expression Through Estrogen Receptor-&agr; in a Rodent Experimental Stroke Model

L. McCullough, K. Korach, A. Ardelt, 2005, Stroke.

Effects of Combined Estrogen and Progesterone on Brain Infarction in Reproductively Senescent Female Rats

P. Hurn, S. Murphy, M. Littleton-Kearney, 2004, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Effects of Combined Oral Conjugated Estrogens and Medroxyprogesterone Acetate on Brain Infarction Size after Experimental Stroke in Rat

P. Hurn, M. Littleton-Kearney, J. Klaus, 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Effects of Estrogen on Platelet Reactivity After Transient Forebrain Ischemia in Rats

P. Hurn, S. Murphy, M. Littleton-Kearney, 2005, Biological research for nursing.

Lack of Sex-Linked Differences in Cerebral Edema and Aquaporin-4 Expression after Experimental Stroke

O. Ottersen, N. Alkayed, P. Hurn, 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Stroke in estrogen receptor-alpha-deficient mice.

B. Crain, R. Traystman, K. Korach, 2000, Stroke.

Low molecular weight iron in cerebral ischemic acidosis in vivo.

R. Traystman, P. Hurn, D. Lipscomb, 1998, Stroke.

Deferoxamine reduces early metabolic failure associated with severe cerebral ischemic acidosis in dogs.

R. Koehler, R. Traystman, P. Hurn, 1995, Stroke.

Membrane restraint of estrogen receptor alpha enhances estrogen-dependent nuclear localization and genomic function.

R. Traystman, Michael M. Wang, P. Hurn, 2004, Molecular endocrinology.

Neurite‐localized estrogen receptor‐α mediates rapid signaling by estrogen

R. Traystman, Michael M. Wang, P. Hurn, 2003 .

Gender and the Injured Brain

P. Hurn, I. Koerner, K. Vágnerová, 2008, Anesthesia and analgesia.

Experimental Stroke in the Female Diabetic, db/db, Mouse

S. Vannucci, T. Wood, I. Simpson, 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Incomplete global cerebral ischemia alters platelet biology in neonatal and adult sheep.

R. Traystman, P. Hurn, M. Littleton-Kearney, 1998, The American journal of physiology.

Incomplete global cerebral ischemia alters platelet biology in neonatal and adult sheep.

R. Traystman, P. Hurn, M. Littleton-Kearney, 1998, American journal of physiology. Heart and circulatory physiology.

Estrogen and Stroke

L. Brass, P. Hurn, 2003 .

Sex shapes experimental ischemic brain injury

P. Hurn, Jian Cheng, 2010, Steroids.

Gender differences in pediatric stroke: Is elevated testosterone a risk factor for boys?

S. Vannucci, P. Hurn, 2009, Annals of neurology.

Programmed Death-1 Pathway Limits Central Nervous System Inflammation and Neurologic Deficits in Murine Experimental Stroke

P. Hurn, K. Akiyoshi, A. Vandenbark, 2011, Stroke.

Sigma Receptor Agonists Provide Neuroprotection In Vitro by Preserving bcl-2

Sufang Yang, N. Alkayed, P. Hurn, 2007, Anesthesia and analgesia.

Social Stress Exacerbates Focal Cerebral Ischemia in Mice

R. Traystman, N. Sugo, P. Hurn, 2002, Stroke.

Dependence of cerebral energy phosphate and evoked potential recovery on end-ischemic pH.

R. Koehler, R. Traystman, P. Hurn, 1991, The American journal of physiology.

Testosterone exacerbates neuronal damage following cardiac arrest and cardiopulmonary resuscitation in mouse

R. Traystman, P. Hurn, P. Herson, 2010, Brain Research.

Testosterone as a Modulator of Vascular Behavior

P. Hurn, M. Littleton-Kearney, 2004, Biological research for nursing.

Middle-Age Male Mice Have Increased Severity of Experimental Autoimmune Encephalomyelitis and Are Unresponsive to Testosterone Therapy1

P. Hurn, A. Vandenbark, H. Offner, 2005, The Journal of Immunology.

Encephalomyelitis and Are Unresponsive to Severity of Experimental Autoimmune Middle-Age Male Mice Have Increased

P. Hurn, A. Vandenbark, H. Offner, 2005 .

Systemic Immune Responses after Experimental Stroke

P. Hurn, H. Offner, 2014 .

Amelioration of impaired cerebral metabolism after severe acidotic ischemia by tirilazad posttreatment in dogs.

E. Hall, R. Koehler, R. Traystman, 1996, Stroke.

Estrogen restores postischemic pial microvascular dilation.

R. Traystman, P. Hurn, Y. Watanabe, 2001, American journal of physiology. Heart and circulatory physiology.

Estradiol abolishes reduction in cell death by the opioid agonist Met5-enkephalin after oxygen glucose deprivation in isolated cardiomyocytes from both sexes.

P. Hurn, W. Packwood, M. Merkel, 2008, American journal of physiology. Heart and circulatory physiology.

Differential Effect of PARP-2 Deletion on Brain Injury after Focal and Global Cerebral Ischemia

R. Traystman, R. Noppens, M. Grafe, 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Soluble epoxide hydrolase gene deletion reduces survival after cardiac arrest and cardiopulmonary resuscitation.

R. Traystman, N. Alkayed, P. Hurn, 2008, Resuscitation.

Histopathological and behavioral characterization of a novel model of cardiac arrest and cardiopulmonary resuscitation in mice

R. Traystman, L. Martin, P. Hurn, 2004, Journal of Neuroscience Methods.

Dietary soy may not confound acute experimental stroke infarct volume outcomes in ovariectomized female rats

P. Hurn, K. Prongay, S. Murphy, 2010, Laboratory animals.

Dose-dependent neuroprotection by 17β-estradiol after cardiac arrest and cardiopulmonary resuscitation

R. Traystman, R. Noppens, P. Hurn, 2005, Critical care medicine.

Estrogen Receptor Antagonist ICI182,780 Exacerbates Ischemic Injury in Female Mouse

B. Crain, R. Traystman, N. Alkayed, 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

High-dose ibuprofen for reduction of striatal infarcts during middle cerebral artery occlusion in rats.

R. Tamargo, R. Traystman, R. Clatterbuck, 2003, Journal of neurosurgery.

Effect of postischemic hypoperfusion on vasodilatory mechanisms in cats.

R. Traystman, P. Hurn, J. Kirsch, 1994, The American journal of physiology.

Neuroprotective Effect of s 1 -Receptor Ligand 4-Phenyl-1-(4-Phenylbutyl) Piperidine (PPBP) Is Linked to Reduced Neuronal Nitric Oxide Production

V. Dawson, P. Hurn, J. Kirsch, 2001 .

Neuroprotection and P450 2C11 Upregulation After Experimental Transient Ischemic Attack

R. Traystman, N. Alkayed, P. Hurn, 2002, Stroke.

Neuroprotection and P 450 2 C 11 Upregulation After Experimental Transient Ischemic Attack

R. Traystman, N. Alkayed, P. Hurn, 2002 .

Cells and Circulating Macrophages Accompanied by Increased Regulatory T Splenic Atrophy in Experimental Stroke Is

P. Hurn, A. Vandenbark, H. Offner, 2006 .

Pial microvascular hemodynamics in anemia.

A. Shoukas, R. Traystman, P. Hurn, 1993, The American journal of physiology.

Estradiol and G1 Reduce Infarct Size and Improve Immunosuppression after Experimental Stroke

Bing Zhang, P. Hurn, K. Akiyoshi, 2010, The Journal of Immunology.

Progesterone Administration during Reperfusion, but not Preischemia Alone, Reduces Injury in Ovariectomized Rats

P. Hurn, S. Murphy, M. Littleton-Kearney, 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Estrogen Restores Postischemic Sensitivity to the Thromboxane Mimetic U46619 in Rat Pial Artery

P. Hurn, M. Littleton-Kearney, Xinyue Qin, 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

A novel method for assessing sex-specific and genotype-specific response to injury in astrocyte culture

P. Hurn, S. Murphy, E. Oyarzabal, 2008, Journal of Neuroscience Methods.

Gender, sex steroids, and cerebral ischemic pathobiology

P. Hurn, S. Murphy, I. Koerner, 2007 .

Soluble epoxide hydrolase: regulation by estrogen and role in the inflammatory response to cerebral ischemia.

N. Alkayed, P. Hurn, Jian Cheng, 2008, Frontiers in bioscience : a journal and virtual library.

Estradiol Alters Only GAD67 mRNA Levels in Ischemic Rat Brain with No Consequent Effects on GABA

R. Koehler, N. Alkayed, P. Hurn, 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Cerebral Ischemia: Pathophysiology and Neuroprotection

R. Traystman, P. Hurn, A. Bhardwaj, 2002 .

Reproductive Hormones as Neuroprotectants in Brain Injury

Michael M. Wang, N. Alkayed, P. Hurn, 2001 .

Estrogen Decreases Infarct Size After Temporary Focal Ischemia in a Genetic Model of Type 1 Diabetes Mellitus

R. Traystman, P. Hurn, F. Sieber, 2000, Stroke.

Sigma 1 Receptor Agonists Act as Neuroprotective Drugs Through Inhibition of Inducible Nitric Oxide Synthase

P. Hurn, J. Kirsch, A. Bhardwaj, 2006, Anesthesia and analgesia.

Non-classical regulation of estrogen receptor-α by ICI182,780

R. Traystman, Michael M. Wang, P. Hurn, 2004, The Journal of Steroid Biochemistry and Molecular Biology.

Sex Differences in Neuroprotection Provided by Inhibition of TRPM2 Channels following Experimental Stroke

M. Grafe, P. Hurn, P. Herson, 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Sex differences in the mechanism of Met5-enkephalin-induced cardioprotection: role of PI3K/Akt.

P. Hurn, W. Packwood, M. Merkel, 2008, American journal of physiology. Heart and circulatory physiology.

Lack of correlation of vaginal impedance measurements with hormone levels in the rat.

J. Watson, D. Huso, P. Hurn, 2005, Contemporary topics in laboratory animal science.

Deleterious effect of beta-estradiol in a rat model of transient forebrain ischemia.

B. Crain, P. Hurn, I. Harukuni, 2001, Brain research.

Postischemic cerebral blood flow recovery in the female: effect of 17 beta-estradiol.

R. Traystman, P. Hurn, J. Kirsch, 1995, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

SOD1 Overexpression and Female Sex Exhibit Region-Specific Neuroprotection after Global Cerebral Ischemia Due to Cardiac Arrest

R. Traystman, P. Hurn, J. Kofler, 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

LY353381.HCl, a Selective Estrogen Receptor Modulator, and Experimental Stroke

R. Traystman, P. Hurn, S. Murphy, 2000, Stroke.

17 (cid:98) -Estradiol Reduces Stroke Injury in Estrogen-Deficient Female Animals

R. Traystman, E. London, N. Alkayed, 1999 .

Ischemic Neuroprotection With Selective &kgr;-Opioid Receptor Agonist Is Gender Specific

R. Koehler, P. Hurn, A. Bhardwaj, 2005, Stroke.

Anish-Opioid Receptor Agonist Is Gender Specific κ Ischemic Neuroprotection With Selective

R. Koehler, P. Hurn, A. Bhardwaj, 2005 .

Kappa-Opioid Receptor Selectivity for Ischemic Neuroprotection with BRL 52537 in Rats

R. Koehler, R. Traystman, P. Hurn, 2003, Anesthesia and analgesia.

Sex, Steroids, and Stroke: Introduction

R. Sacco, P. Hurn, 2004 .

Myelin specific cells infiltrate MCAO lesions and exacerbate stroke severity

M. Grafe, P. Hurn, K. Akiyoshi, 2011, Metabolic Brain Disease.

The effect of brief halothane anesthesia during daily gavage on complications and body weight in rats.

P. Hurn, S. Murphy, A. Shaivitz, 2001, Contemporary topics in laboratory animal science.

Neuroprotective effect of sigma(1)-receptor ligand 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) is linked to reduced neuronal nitric oxide production.

V. Dawson, P. Hurn, J. Kirsch, 2001, Stroke.

Gender-linked brain injury in experimental stroke.

R. Traystman, E. London, N. Alkayed, 1998, Stroke.

Progesterone and allopregnanolone as neuroprotectants in ischemic ovariectomized mouse brain

P. Hurn, S. Murphy, S. Parker, 2005 .

Soluble epoxide hydrolase gene deletion reduces inflammation after stroke

N. Alkayed, P. Hurn, D. Koop, 2005 .

Treatment with the competitive NMDA antagonist GPI 3000 does not improve outcome after cardiac arrest in dogs.

R. Ichord, R. Traystman, M. Helfaer, 1998, Stroke.

Poly (ADP-ribose) polymerase and brain ischemia

R. Traystman, L. Martin, V. Dawson, 2003 .

Local Anesthetic Schwann Cell Toxicity Is Time and Concentration Dependent

M. Grafe, Sufang Yang, P. Hurn, 2011, Regional Anesthesia & Pain Medicine.

Impaired Limb Reaction to Displacement of Center of Gravity in Rats with Unilateral Striatal Ischemic Injury

D. Adkins, T. Schallert, J. Kane, 2014, Translational Stroke Research.

Tirilazad Mesylate Does Not Improve Early Cerebral Metabolic Recovery Following Compression Ischemia in Dogs

R. Koehler, R. Traystman, M. Helfaer, 1992, Stroke.

CD4+FoxP3+ regulatory T-cells in cerebral ischemic stroke

P. Hurn, K. Akiyoshi, A. Vandenbark, 2011, Metabolic Brain Disease.

Role of dihydrotestosterone in post-stroke peripheral immunosuppression after cerebral ischemia

P. Hurn, K. Akiyoshi, H. Offner, 2011, Brain, Behavior, and Immunity.

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia

S. Snyder, R. Traystman, Zhao-Qi Wang, 1997, Nature Medicine.

Neuroprotective &kgr;-Opioid Receptor Agonist BRL 52537 Attenuates Ischemia-Evoked Nitric Oxide Production In Vivo in Rats

R. Koehler, R. Traystman, P. Hurn, 2003, Stroke.

Effects of Sex Steroids on Damaged Neural Systems

D. Stein, P. Hurn, 2009 .

Neuroprotective effect of σ1-receptor ligand 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) is linked to reduced neuronal nitric oxide production

V. Dawson, P. Hurn, J. Kirsch, 2001 .

Nitric Oxide and Cerebral Ischemia

R. Traystman, P. Hurn, J. Kirsch, 2000 .

Nitro-L-arginine analogues. Dose- and time-related nitric oxide synthase inhibition in brain.

R. Traystman, M. Helfaer, P. Hurn, 1995, Stroke.

Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations

Marc Fisher, Thomas A. Kent, David W. Howells, 2009, Stroke.

Considering sex as a biological variable in preclinical research

Cora Lee Wetherington, A. Arnold, J. Clayton, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Renal Ischemia: Does Sex Matter?

P. Hurn, M. Hutchens, J. Dunlap, 2008, Anesthesia and analgesia.

Experimental Stroke Induces Massive, Rapid Activation of the Peripheral Immune System

P. Hurn, A. Vandenbark, H. Offner, 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Sex differences in stroke: Challenges and opportunities

L. McCullough, M. Jimenez, M. Reeves, 2018, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Cognitive and behavioral assessment in experimental stroke research: will it prove useful?

R. Traystman, R. Nelson, P. Hurn, 2001, Neuroscience & Biobehavioral Reviews.

Biological Sex and Mechanisms of Ischemic Brain Injury

P. Hurn, P. Herson, J. Palmateer, 2013, Translational Stroke Research.

Impaired Limb Reaction to Displacement of Center of Gravity in Rats with Unilateral Striatal Ischemic Injury

D. Adkins, T. Schallert, J. Kane, 2014, Translational Stroke Research.

Progesterone exacerbates striatal stroke injury in progesterone-deficient female animals

R. Traystman, P. Hurn, S. Murphy, 2000, Stroke.

A Novel Hypothesis: Regulatory B Lymphocytes Shape Outcome from Experimental Stroke

P. Hurn, H. Offner, 2012, Translational Stroke Research.

Ischemic Nitric Oxide and Poly (ADP-Ribose) Polymerase-1 in Cerebral Ischemia: Male Toxicity, Female Protection

L. McCullough, P. Hurn, K. Blizzard, 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Role of Soluble Epoxide Hydrolase in the Sex-Specific Vascular Response to Cerebral Ischemia

Ruikang K. Wang, J. Iliff, N. Alkayed, 2009, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Role of Signal Transducer and Activator of Transcription-3 in Estradiol-Mediated Neuroprotection

O. Rønnekleiv, N. Alkayed, P. Hurn, 2007, The Journal of Neuroscience.

Role of cocaine- and amphetamine-regulated transcript in estradiol-mediated neuroprotection

F. Martínez-Murillo, N. Alkayed, P. Hurn, 2006, Proceedings of the National Academy of Sciences.

Novel Humanized Recombinant T Cell Receptor Ligands Protect the Female Brain After Experimental Stroke

T. Schallert, P. Hurn, Jie Pan, 2014, Translational Stroke Research.

Estrogen Enhances Neurogenesis and Behavioral Recovery after Stroke

L. McCullough, P. Hurn, Jun Li, 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Postischemic Estrogen Reduces Hypoperfusion and Secondary Ischemia After Experimental Stroke

L. McCullough, R. Traystman, N. Alkayed, 2001, Stroke.

Stroke Outcome in Double-Mutant Antioxidant Transgenic Mice

R. Traystman, T. Dawson, V. Dawson, 2000, Stroke.

Estrogen-mediated neuroprotection after experimental stroke in male rats.

R. Traystman, P. Hurn, T. Toung, 1998, Stroke.

Effects of Androgens on Early Post-ischemic Neurogenesis in Mice

A. Brambrink, M. Grafe, P. Hurn, 2013, Translational Stroke Research.

Effects of estrogen on cerebral blood flow and pial microvasculature in rabbits.

R. Traystman, P. Hurn, M. Littleton-Kearney, 2000, American journal of physiology. Heart and circulatory physiology.

Treatment modalities for hypertensive patients with intracranial pathology: options and risks.

J. Ulatowski, P. Hurn, J. Kirsch, 1996, Critical care medicine.

Treating hypertensive patients with intracranial pathology [2]

J. Ulatowski, M. Malbrain, P. Hurn, 1996 .

Anesthetic Choice of Halothane Versus Propofol: Impact on Experimental Perioperative Stroke

N. Alkayed, P. Hurn, J. Kirsch, 2001, Stroke.

Estrogen and ischemic neuroprotection: an integrated view

L. McCullough, P. Hurn, 2003, Trends in Endocrinology & Metabolism.

Poly(ADP-Ribose) Polymerase Impairs Early and Long-Term Experimental Stroke Recovery

S. Mori, B. Crain, R. Xue, 2002, Stroke.

Postischemic Cerebral Blood Flow Recovery in the Female: Effect of 17β-Estradiol

R. Traystman, P. Hurn, J. Kirsch, 1995 .

Biological Sex and Mechanisms of Ischemic Brain Injury

P. Hurn, P. Herson, J. Palmateer, 2012, Translational Stroke Research.

Role of Salt-Induced Kinase 1 in Androgen Neuroprotection against Cerebral Ischemia

M. Grafe, P. Hurn, Jian Cheng, 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Adult or Perinatal Brain Injury: Does Sex Matter?

S. Vannucci, H. Hagberg, P. Hurn, 2005, Stroke.

Evidence of the peripheral inflammatory response in patients with transient ischemic attack.

N. Perrin, P. Hurn, K. Potempa, 2007, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

Androgen Receptor Overexpression Is Neuroprotective in Experimental Stroke

O. Rønnekleiv, P. Hurn, Jian Cheng, 2011, Translational Stroke Research.

Estrogen as a Neuroprotectant in Stroke

P. Hurn, I. Macrae, I. Macrae, 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Hypertonic saline worsens infarct volume after transient focal ischemia in rats.

B. Crain, R. Koehler, R. Traystman, 2000, Stroke.

Neuroprotective Effect of Selective Kappa Opioid Receptor Agonist is Gender Specific and Linked to Reduced Neuronal Nitric Oxide

R. Koehler, M. Nemoto, P. Hurn, 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Age-Dependent Effects of Testosterone in Experimental Stroke

T. Toung, P. Hurn, Jian Cheng, 2009, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Non-classical regulation of estrogen receptor-alpha by ICI182,780.

R. Traystman, Michael M. Wang, P. Hurn, 2004, The Journal of steroid biochemistry and molecular biology.

Estrogen and Stroke: A Balanced Analysis

L. Brass, P. Hurn, 2003, Stroke.

Advancing the Study of Stroke in Women: Summary and Recommendations for Future Research From an NINDS-Sponsored Multidisciplinary Working Group

L. Newby, P. Gorelick, L. Goldstein, 2006, Stroke.

Deleterious effect of β-estradiol in a rat model of transient forebrain ischemia

Izumi Harukuni, B. Crain, P. Hurn, 2001, Brain Research.

Neonatal factors influence adult stroke outcome

P. Hurn, A. Devries, E. Glasper, 2006, Psychoneuroendocrinology.

Social stress exacerbates stroke outcome by suppressing Bcl-2 expression

R. Traystman, O. Bernard, N. Alkayed, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Developmental Exposure to Polychlorinated Biphenyls Influences Stroke Outcome in Adult Rats

N. Alkayed, P. Hurn, P. Lein, 2008, Environmental health perspectives.

2014 Thomas Willis Award Lecture: sex, stroke, and innovation.

P. Hurn, 2014, Stroke.

Evaluating Behavioral Outcomes from Ischemic Brain Injury

P. Hurn, A. Devries, P. Herson, 2011 .

Effects of gender and sex steroids on ischemic injury.

L. McCullough, P. Hurn, I. Koerner, 2009, Handbook of clinical neurology.

Risk Factors: Gender and Sex

F. Sohrabji, P. Hurn, 2017 .

Deleterious Effects of Dihydrotestosterone on Cerebral Ischemic Injury

N. Alkayed, P. Hurn, Jian Cheng, 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Research Spanning Animal and Human Models: The Role of Serendipity, Competition, and Strategic Actions in Advancing Stroke Research

R. Traystman, P. Hurn, 2019, Strategies for Team Science Success.

Gender-based Differences in Na+–K+ Adenosine Triphosphatase Activity Occur in the Microcirculation of the Diabetic Rat Brain

R. Traystman, N. Alkayed, P. Hurn, 2001, Anesthesiology.

Sex, hormones and the endothelium

L. McCullough, P. Hurn, S. Murphy, 2004 .

Potent sigma 1-receptor ligand 4-phenyl-1-(4-phenylbutyl) piperidine provides ischemic neuroprotection without altering dopamine accumulation in vivo in rats.

R. Koehler, R. Traystman, P. Hurn, 2003, Anesthesia and analgesia.

Prolonged Opportunity for Ischemic Neuroprotection with Selective κ-Opioid Receptor Agonist in Rats

R. Koehler, P. Hurn, J. Kirsch, 2004, Stroke.

Agonist in Rats-Opioid Receptor κ Prolonged Opportunity for Ischemic Neuroprotection with Selective

R. Koehler, P. Hurn, J. Kirsch, 2004 .

improved myocardial function in female hearts following acute ischemia Estrogen receptor {beta} mediates increased activation of PI3K/Akt signaling and

Jun Ren, D. Meldrum, J. Duan, 2009 .

Selective estrogen receptor modulators: tissue actions and potential for CNS protection.

P. Hurn, D. Cox, M. Littleton-Kearney, 2006, CNS drug reviews.

Estrogen Is Renoprotective via a Nonreceptor-dependent Mechanism after Cardiac Arrest In Vivo

S. Anderson, P. Hurn, S. Murphy, 2010, Anesthesiology.

Brain Aromatization: Classic Roles and New Perspectives

P. Hurn, C. Roselli, Patricia D Hurn, 2009, Seminars in reproductive medicine.

Ultrasonic vocalization in murine experimental stroke: A mechanistic model of aphasia.

T. Jones, T. Schallert, A. Gore, 2016, Restorative neurology and neuroscience.

Myelin specific cells infiltrate MCAO lesions and exacerbate stroke severity

M. Grafe, P. Hurn, K. Akiyoshi, 2012, Metabolic Brain Disease.

Thrombin Mutant W215A/E217A Treatment Improves Neurological Outcome and Reduces Cerebral Infarct Size in a Mouse Model of Ischemic Stroke

Ruikang K. Wang, M. Berny-Lang, O. McCarty, 2011, Stroke.

Nitric Oxide Production In Vivo in Rats-Opioid Receptor Agonist BRL 52537 Attenuates Ischemia-Evoked κ Neuroprotective

R. Koehler, R. Traystman, P. Hurn, 2003 .

Dose-Dependent Effects of Androgens on Outcome after Focal Cerebral Ischemia in Adult Male Mice

Jian Cheng, P. Hurn, Jian Cheng, 2009, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Estrogen Increases cGMP in Selected Brain Regions and in Cerebral Microvessels

R. Traystman, P. Hurn, D. Kosk-Kosicka, 1998, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Recombinant T Cell Receptor Ligands Improve Outcome After Experimental Cerebral Ischemia

P. Hurn, K. Akiyoshi, A. Vandenbark, 2011, Translational Stroke Research.

Lone Star Stroke Consortium

J. Grotta, T. Kent, S. Warach, 2020, Stroke.

Social Interaction Improves Experimental Stroke Outcome

L. McCullough, Ning Zhang, N. Sugo, 2005, Stroke.

Ischemic insult to cerebellar Purkinje cells causes diminished GABAA receptor function and allopregnanolone neuroprotection is associated with GABAA receptor stabilization

Richard J Traystman, Ardalan Ardeshiri, R. Traystman, 2008, Journal of neurochemistry.

Estrogen and Bcl-2: Gene Induction and Effect of Transgene in Experimental Stroke

R. Traystman, O. Bernard, N. Alkayed, 2001, The Journal of Neuroscience.

Neuronal overexpression of cyclooxygenase‐2 increases cerebral infarction

R. Traystman, S. Doré, P. Hurn, 2003, Annals of neurology.

Neuroprotective FK506 does not alter in vivo nitric oxide production during ischemia and early reperfusion in rats.

R. Traystman, T. Dawson, V. Dawson, 1999, Stroke.

Cerebral blood flow is reduced by N omega-nitro-L-arginine methyl ester during delayed hypoperfusion in cats.

R. Traystman, P. Hurn, J. Kirsch, 1994, American Journal of Physiology.

Mitochondrial mechanism of neuroprotection by CART

Sufang Yang, N. Alkayed, P. Hurn, 2007, The European journal of neuroscience.

Mechanisms of ischemic brain damage

N. Alkayed, P. Hurn, J. Kirsch, 2003, Current cardiology reports.

Catecholaminergic Control of Mitogen-Activated Protein Kinase Signaling in Paraventricular Neuroendocrine Neurons In Vivo and In Vitro: A Proposed Role during Glycemic Challenges

Alan G. Watts, Glenn I. Hatton, A. Thomson, 2007, The Journal of Neuroscience.

Poly (ADP-ribose) polymerase-1 initiated neuronal cell death pathway—do androgens matter?

P. Hurn, Jian Cheng, S. Murphy, 2010, Neuroscience.

Parallel antioxidant and antiexcitotoxic therapy improves outcome after incomplete global cerebral ischemia in dogs.

R. Traystman, M. Helfaer, P. Hurn, 1997, Stroke.

Cytochrome P450 in neurological disease.

N. Alkayed, P. Hurn, M. Liu, 2004, Current drug metabolism.

Cyclic Adenosine Monophosphate Response Element-Binding Protein Phosphorylation and Neuroprotection by 4-Phenyl-1-(4-Phenylbutyl) Piperidine (PPBP)

Sufang Yang, N. Alkayed, P. Hurn, 2009 .

Neuroprotection of sex steroids.

P. Hurn, P. Herson, P. Hurn, 2010, Minerva endocrinologica.

Heme Oxygenase-2 Is Neuroprotective in Cerebral Ischemia

S. Snyder, D. Guastella, R. Koehler, 1999, Molecular medicine.

Estrogen Is Renoprotective via a Nonreceptor-dependent Mechanism after Cardiac Arrest In Vivo

S. Anderson, P. Hurn, S. Murphy, 2010, Anesthesiology.

Anticonvulsant Lamotrigine Administered on Reperfusion Fails To Improve Experimental Stroke Outcomes

R. Traystman, P. Hurn, A. Devries, 2001, Stroke.

Mechanism of progesterone neuroprotection of rat cerebellar Purkinje cells following oxygen–glucose deprivation

P. Hurn, P. Herson, P. Hurn, 2006, The European journal of neuroscience.

Experimental Stroke Improve Immunosuppression after Estradiol and G1 Reduce Infarct Size And

P. Hurn, K. Akiyoshi, A. Vandenbark, 2022 .

Traystman and Patricia D. Hurn Neuroprotection and P450 2c11 Upregulation after Experimental Transient Ischemic Neuroprotection and P450 2c11 Upregulation after Experimental Transient Ischemic Attack

R. Traystman, P. Hurn, D. Harder, 2022 .

Administration of Selective Endothelin Receptor Type a Antagonist Ro 61-1790 Does Not Improve Outcome in Focal Cerebral Ischemia in Cat

R. Traystman, P. Hurn, J. Kirsch, 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Female gender exacerbates respiratory depression in leptin-deficient obesity.

P. L. Smith, P. Hurn, V. Polotsky, 2001, American journal of respiratory and critical care medicine.