H. Kim

Jae Heun Lee, H. Seo, K. Chang, 2009, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

NLRC4, ASC and Caspase-1 Are Inflammasome Components That Are Mediated by P2Y2R Activation in Breast Cancer Cells

H. Kim, Hana Jin, H. J. Kim, 2020, International journal of molecular sciences.

2-methoxycinnamaldehyde from Cinnamomum cassia reduces rat myocardial ischemia and reperfusion injury in vivo due to HO-1 induction.

Jae Heun Lee, Y. M. Kim, K. Chang, 2012, Journal of ethnopharmacology.

YS 49, 1-(alpha-naphtylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, regulates angiotensin II-stimulated ROS production, JNK phosphorylation and vascular smooth muscle cell proliferation via the induction of heme oxygenase-1.

Jae Heun Lee, H. Seo, K. Chang, 2008, Life sciences.

PPARδ promotes wound healing by up-regulating TGF-β1-dependent or -independent expression of extracellular matrix proteins

Jae Heun Lee, Hyun Joon Kim, E. S. Kang, 2009, Journal of cellular and molecular medicine.

Degradation of histone deacetylase 4 via the TLR4/JAK/STAT1 signaling pathway promotes the acetylation of high mobility group box 1 (HMGB1) in lipopolysaccharide‐activated macrophages

E. Park, Y. M. Kim, K. Chang, 2018, FEBS open bio.

Induction of HO-1 through p38 MAPK/Nrf2 signaling pathway by ethanol extract of Inula helenium L. reduces inflammation in LPS-activated RAW 264.7 cells and CLP-induced septic mice.

Jae Heun Lee, E. Park, Y. M. Kim, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Ethyl pyruvate induces heme oxygenase-1 through p38 mitogen-activated protein kinase activation by depletion of glutathione in RAW 264.7 cells and improves survival in septic animals.

Jae Heun Lee, E. Park, K. Tsoyi, 2012, Antioxidants & redox signaling.

Metformin inhibits HMGB1 release in LPS‐treated RAW 264.7 cells and increases survival rate of endotoxaemic mice

Jae Heun Lee, K. Tsoyi, Y. M. Kim, 2011, British journal of pharmacology.

β₁-adrenergic receptor-mediated HO-1 induction, via PI3K and p38 MAPK, by isoproterenol in RAW 264.7 cells leads to inhibition of HMGB1 release in LPS-activated RAW 264.7 cells and increases in survival rate of CLP-induced septic mice.

Jae Heun Lee, Y. M. Kim, H. Seo, 2011, Biochemical pharmacology.

DIRECT EFFECT OF DEXMEDETOMIDINE ON RAT ISOLATED AORTA INVOLVES ENDOTHELIAL NITRIC OXIDE SYNTHESIS AND ACTIVATION OF THE LIPOXYGENASE PATHWAY

K. Chang, H. Kim, Chang-Shin Park, 2009, Clinical and experimental pharmacology & physiology.

Flavonoids from Orostachys japonicus A. Berger Inhibit the Invasion of LnCaP Prostate Carcinoma Cells by Inactivating Akt and Modulating Tight Junctions

Soon-Chan Hong, Yung-Hyun Choi, W. Lee, 2013, International journal of molecular sciences.

ESM-1 Overexpression is Involved in Increased Tumorigenesis of Radiotherapy-Resistant Breast Cancer Cells

H. Kim, S. Park, S. Yun, 2020, Cancers.

Palmatine from Coptidis rhizoma reduces ischemia-reperfusion-mediated acute myocardial injury in the rat.

Jae Heun Lee, Y. M. Kim, H. Seo, 2009, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

p53 Enhances Artemisia annua L. Polyphenols-Induced Cell Death Through Upregulation of p53-Dependent Targets and Cleavage of PARP1 and Lamin A/C in HCT116 Colorectal Cancer Cells

Soon-Chan Hong, E. Jung, W. Lee, 2020, International journal of molecular sciences.

Transcriptional up-regulation of antioxidant genes by PPARδ inhibits angiotensin II-induced premature senescence in vascular smooth muscle cells.

Min Young Kim, Chang Woo Han, Jae Heun Lee, 2011, Biochemical and biophysical research communications.

Akt-dependent heme oxygenase-1 induction by NS-398 in C6 glial cells: A potential role for CO in prevention of oxidative damage from hypoxia

Jae Heun Lee, Y. M. Kim, H. Seo, 2007, Neuropharmacology.

Doxorubicin-Resistant TNBC Cells Exhibit Rapid Growth with Cancer Stem Cell-like Properties and EMT Phenotype, Which Can Be Transferred to Parental Cells through Autocrine Signaling

E. Jung, W. Lee, H. Kim, 2021, International journal of molecular sciences.

Luteolin activates ERK1/2- and Ca2+-dependent HO-1 induction that reduces LPS-induced HMGB1, iNOS/NO, and COX-2 expression in RAW264.7 cells and mitigates acute lung injury of endotoxin mice

E. Park, Y. M. Kim, K. Chang, 2018, Inflammation Research.

Polyphenols Isolated from Allium cepa L. Induces Apoptosis by Induction of p53 and Suppression of Bcl-2 through Inhibiting PI3K/Akt Signaling Pathway in AGS Human Cancer Cells

Soon-Chan Hong, Yung-Hyun Choi, W. Lee, 2014, Journal of cancer prevention.

Polyphenols isolated from Allium cepa L. induces apoptosis by suppressing IAP-1 through inhibiting PI3K/Akt signaling pathways in human leukemic cells.

Soon-Chan Hong, Yung-Hyun Choi, W. Lee, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

P2Y2R activation by nucleotides promotes skin wound‐healing process

Jae Heun Lee, K. Chang, H. Kim, 2014, Experimental dermatology.

IL-1β enhances vascular smooth muscle cell proliferation and migration via P2Y2 receptor-mediated RAGE expression and HMGB1 release.

K. Chang, H. Kim, S. Park, 2015, Vascular pharmacology.

Daidzein administration in vivo reduces myocardial injury in a rat ischemia/reperfusion model by inhibiting NF-kappaB activation.

Jae Heun Lee, Y. M. Kim, H. Seo, 2009, Life sciences.

Morin, a Flavonoid from Moraceae, Inhibits Cancer Cell Adhesion to Endothelial Cells and EMT by Downregulating VCAM1 and Ncadherin.

Soon-Chan Hong, Yung-Hyun Choi, A. Nagappan, 2016, Asian Pacific journal of cancer prevention : APJCP.

Flavonoids from Citrus unshiu Marc. inhibit cancer cell adhesion to endothelial cells by selective inhibition of VCAM-1.

Soon-Chan Hong, Yung-Hyun Choi, W. Lee, 2013, Oncology reports.

Effect of Garcinia cambogia Extract-containing Dip-sauce for Meat on Lipid Accumulation and Body Weight Reduction in Rats Fed High-fat Diet

E. S. Kang, H. Seo, H. Kim, 2013 .

Flavonoids Isolated from Flowers of Lonicera japonica Thunb. Inhibit Inflammatory Responses in BV2 Microglial Cells by Suppressing TNF‐α and IL‐β Through PI3K/Akt/NF‐kb Signaling Pathways

Soon-Chan Hong, Yung-Hyun Choi, A. Nagappan, 2016, Phytotherapy research : PTR.

P2Y2R contributes to the development of diabetic nephropathy by inhibiting autophagy response

S. Kim, E. Park, H. Kim, 2020, Molecular metabolism.

Up-regulation of aldose reductase expression mediated by phosphatidylinositol 3-kinase/Akt and Nrf2 is involved in the protective effect of curcumin against oxidative damage.

Jae Heun Lee, C. Yabe-Nishimura, E. S. Kang, 2007, Free radical biology & medicine.

Nrf2 regulates curcumin-induced aldose reductase expression indirectly via nuclear factor-kappaB.

Min Young Kim, Jae Heun Lee, E. S. Kang, 2008, Pharmacological research.

Magnolia officinalis attenuates free fatty acid-induced lipogenesis via AMPK phosphorylation in hepatocytes.

K. Chang, H. Kim, S. Park, 2014, Journal of ethnopharmacology.

Polyphenol mixtures of Euphorbia supina the inhibit invasion and metastasis of highly metastatic breast cancer MDA-MB-231 cells.

Yung-Hyun Choi, W. Lee, S. Shin, 2015, Oncology reports.

Anthocyanins from soybean seed coat inhibit the expression of TNF‐α‐induced genes associated with ischemia/reperfusion in endothelial cell by NF‐κB‐dependent pathway and reduce rat myocardial damages incurred by ischemia and reperfusion in vivo

S. Shin, J. Chung, K. Chang, 2006, FEBS letters.

Anthocyanins from black soybean seed coats preferentially inhibit TNF-alpha-mediated induction of VCAM-1 over ICAM-1 through the regulation of GATAs and IRF-1.

Jae Heun Lee, S. Shin, Y. M. Kim, 2009, Journal of agricultural and food chemistry.

Farnesyl diphosphate synthase attenuates paclitaxel-induced apoptotic cell death in human glioblastoma U87MG cells

Jae Heun Lee, Soon-Chan Hong, E. S. Kang, 2010, Neuroscience Letters.

Nobiletin ameliorates hepatic ischemia and reperfusion injury through the activation of SIRT-1/FOXO3a-mediated autophagy and mitochondrial biogenesis

S. Kim, H. Kim, S. Park, 2019, Experimental & Molecular Medicine.

Anthocyanins from black soybean seed coats stimulate wound healing in fibroblasts and keratinocytes and prevent inflammation in endothelial cells.

Jae Heun Lee, S. Shin, Y. M. Kim, 2009, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Activation of peroxisome proliferator‐activated receptor‐δ attenuates glutamate‐induced neurotoxicity in HT22 mouse hippocampal cells

G. Roh, E. S. Kang, H. Seo, 2012, Journal of neuroscience research.

P2Y2R Deficiency Ameliorates Hepatic Steatosis by Reducing Lipogenesis and Enhancing Fatty Acid β-Oxidation through AMPK and PGC-1α Induction in High-Fat Diet-Fed Mice

E. Park, H. Kim, S. Park, 2021, International journal of molecular sciences.

Ascorbic acid reduces HMGB1 secretion in lipopolysaccharide-activated RAW 264.7 cells and improves survival rate in septic mice by activation of Nrf2/HO-1 signals.

S. Kim, E. Park, Y. M. Kim, 2015, Biochemical pharmacology.

Heme oxygenase-1 induction by (S)-enantiomer of YS-51 (YS-51S), a synthetic isoquinoline alkaloid, inhibits nitric oxide production and nuclear factor-kappaB translocation in ROS 17/2.8 cells activated with inflammatory stimulants.

Jae Heun Lee, Hyung-Ryong Kim, H. Seo, 2007, International immunopharmacology.

EP2 receptor activation by prostaglandin E2 leads to induction of HO-1 via PKA and PI3K pathways in C6 cells.

Jae Heun Lee, H. Seo, K. Chang, 2009, Biochemical and biophysical research communications.

Indigo carmine enhances phenylephrine-induced contractions in an isolated rat aorta

K. Chang, H. Kim, Y. Ha, 2011, Korean journal of anesthesiology.

Anti‐inflammatory effects of anthocyanins from black soybean seed coat on the keratinocytes and ischemia‐reperfusion injury in rat skin flaps

S. Shin, J. Chung, K. Chang, 2012, Microsurgery.

Anthocyanins Isolated from Vitis coignetiae Pulliat Enhances Cisplatin Sensitivity in MCF-7 Human Breast Cancer Cells through Inhibition of Akt and NF-κB Activation

Min Jeong Kim, Soon-Chan Hong, E. Jung, 2020, Molecules.

Dehydrocostuslactone inhibits LPS-induced inflammation by p38MAPK-dependent induction of hemeoxygenase-1 in vitro and improves survival of mice in CLP-induced sepsis in vivo.

E. Park, K. Chang, H. Kim, 2014, International immunopharmacology.

(+)-Nootkatone and (+)-valencene from rhizomes of Cyperus rotundus increase survival rates in septic mice due to heme oxygenase-1 induction.

Jae Heun Lee, K. Tsoyi, Y. M. Kim, 2011, Journal of ethnopharmacology.

Anti-inflammatory action of methanol extract of Carthamus tinctorius involves in heme oxygenase-1 induction.

Jae Heun Lee, Y. M. Kim, H. Seo, 2011, Journal of ethnopharmacology.

Carbon monoxide (from CORM-2) inhibits high glucose-induced ICAM-1 expression via AMP-activated protein kinase and PPAR-gamma activations in endothelial cells.

Jae Heun Lee, Y. M. Kim, H. Seo, 2009, Atherosclerosis.

Activation of PPAR-γ by Carbon Monoxide from CORM-2 Leads to the Inhibition of iNOS but not COX-2 Expression in LPS-Stimulated Macrophages

Jae Heun Lee, K. Tsoyi, Y. M. Kim, 2009, Inflammation.

Regulation of Lipopolysaccharide-Induced Inducible Nitric-Oxide Synthase Expression through the Nuclear Factor-κB Pathway and Interferon-β/Tyrosine Kinase 2/Janus Tyrosine Kinase 2-Signal Transducer and Activator of Transcription-1 Signaling Cascades by 2-Naphthylethyl-6,7-dihydroxy-1,2,3,4-tetrahyd

Jae Heun Lee, K. Tsoyi, H. Seo, 2007, Journal of Pharmacology and Experimental Therapeutics.

Geniposide Improves Diabetic Nephropathy by Enhancing ULK1-Mediated Autophagy and Reducing Oxidative Stress through AMPK Activation

E. Park, H. Kim, S. Park, 2021, International journal of molecular sciences.

Selective activation of adrenergic β1 receptors induces heme oxygenase 1 production in RAW264.7 cells

Jae Heun Lee, H. Seo, K. Chang, 2005, FEBS letters.

NS398 protects cells from sodium nitroprusside-mediated cytotoxicity through enhancing HO-1 induction independent of COX-2 inhibition

Jae Heun Lee, H. Seo, K. Chang, 2009, Archives of pharmacal research.

Rosmarinic Acid Increases Macrophage Cholesterol Efflux through Regulation of ABCA1 and ABCG1 in Different Mechanisms

H. Kim, S. Park, S. Yun, 2021, International journal of molecular sciences.

Cryptotanshinone, a lipophilic compound of Salvia miltiorrriza root, inhibits TNF-alpha-induced expression of adhesion molecules in HUVEC and attenuates rat myocardial ischemia/reperfusion injury in vivo.

Y. M. Kim, H. Seo, K. Chang, 2009, European journal of pharmacology.

Supplementation of Abelmoschus manihot Ameliorates Diabetic Nephropathy and Hepatic Steatosis by Activating Autophagy in Mice

S. Kim, H. Kim, S. Park, 2018, Nutrients.

Carbon Monoxide From CORM-2 Reduces HMGB1 Release Through Regulation of IFN-&bgr;/JAK2/STAT-1/INOS/NO Signaling But Not COX-2 in TLR-Activated Macrophages

Jae Heun Lee, K. Tsoyi, H. Seo, 2010, Shock.

Sirt1 S-nitrosylation induces acetylation of HMGB1 in LPS-activated RAW264.7 cells and endotoxemic mice.

E. Park, Y. M. Kim, K. Chang, 2018, Biochemical and biophysical research communications.

Ran suppresses paclitaxel-induced apoptosis in human glioblastoma cells

Chang Woo Han, Jae Heun Lee, H. Seo, 2008, Apoptosis.

Ursodeoxycholic Acid Induces Death Receptor-mediated Apoptosis in Prostate Cancer Cells

Soon-Chan Hong, Yung-Hyun Choi, W. Lee, 2017, Journal of cancer prevention.

Protective effect of anthocyanins from black soybean seed coats on UVB-induced apoptotic cell death in vitro and in vivo.

Jae Heun Lee, S. Shin, K. Tsoyi, 2008, Journal of agricultural and food chemistry.

Pharmacological inhibition of AIMP2 aggregation attenuates α-synuclein aggregation and toxicity in Parkinson's disease.

H. Kim, S. Park, S. Yun, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

YS 51, 1-(beta-naphtylmethyl)-6,7-dihydroxy-1,2,3,4,-tetrahydroisoquinoline, protects endothelial cells against hydrogen peroxide-induced injury via carbon monoxide derived from heme oxygenase-1.

Jae Heun Lee, H. Seo, K. Chang, 2007, Biochemical pharmacology.

Pachymic Acid Induces Apoptosis of EJ Bladder Cancer Cells by DR5 Up‐Regulation, ROS Generation, Modulation of Bcl‐2 and IAP Family Members

Su-Jae Lee, Yung-Hyun Choi, A. Nagappan, 2015, Phytotherapy research : PTR.

CKD712, a synthetic isoquinoline alkaloid, enhances the anti-cancer effects of paclitaxel in MDA-MB-231 cells through regulation of PTEN.

E. Park, K. Tsoyi, Y. M. Kim, 2014, Life sciences.

Ethyl Pyruvate Directly Attenuates Active Secretion of HMGB1 in Proximal Tubular Cells via Induction of Heme Oxygenase-1

H. Kim, S. Park, Hwajin Kim, 2019, Journal of clinical medicine.

13-Ethylberberine reduces HMGB1 release through AMPK activation in LPS-activated RAW264.7 cells and protects endotoxemic mice from organ damage.

K. Chang, H. Kim, Y. Ko, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

The inhibitory effect of anthocyanins on Akt on invasion and epithelial-mesenchymal transition is not associated with the anti-EGFR effect of the anthocyanins.

Min Jeong Kim, Yung-Hyun Choi, W. Lee, 2014, International journal of oncology.

Anthocyanins From the Fruit of Vitis coignetiae Pulliat Potentiate the Cisplatin Activity by Inhibiting PI3K/Akt Signaling Pathways in Human Gastric Cancer Cells

Soon-Chan Hong, Yung-Hyun Choi, A. Nagappan, 2015, Journal of cancer prevention.

(S)‐1‐α‐naphthylmethyl‐6,7‐dihydroxy‐1,2,3,4‐tetrahydroisoquinoline (CKD712), promotes wound closure by producing VEGF through HO‐1 induction in human dermal fibroblasts and mouse skin

Jae Heun Lee, K. Tsoyi, Y. M. Kim, 2013, British journal of pharmacology.

Platycodon grandiflorus Fermented Extracts Attenuate Endotoxin-Induced Acute Liver Injury in Mice

S. Kim, E. Park, H. Kim, 2020, Nutrients.

Dexmedetomidine‐induced contraction involves c‐Jun NH2‐terminal kinase phosphorylation through activation of the 5‐lipoxygenase pathway in the isolated endothelium‐denuded rat aorta

H. Kim, H. Byon, S. Ok, 2014, Clinical and experimental pharmacology & physiology.

C-Jun NH2-Terminal Kinase Contributes to Dexmedetomidine-Induced Contraction in Isolated Rat Aortic Smooth Muscle

K. Chang, H. Kim, Seong-chun Kwon, 2011, Yonsei medical journal.

Peroxisome Proliferator-Activated Receptor &dgr; Regulates Extracellular Matrix and Apoptosis of Vascular Smooth Muscle Cells Through the Activation of Transforming Growth Factor-β1/Smad3

Min Young Kim, Jae Heun Lee, Hyun Joon Kim, 2009, Circulation research.

Peroxisome Proliferator-Activated Receptor (cid:1) Regulates Extracellular Matrix and Apoptosis of Vascular Smooth Muscle Cells Through the Activation of Transforming Growth Factor- (cid:2) 1/Smad3

Jae Heun Lee, Hyun Joon Kim, S. Kang, 2009 .

Effect of Renal Ischemia Reperfusion on Brain Neuroinflammation

E. Park, H. Kim, S. Park, 2022, Biomedicines.

Heme oxygenase-1 induction through p 38 MAPK / Nrf 2 activation by ethanol extract of Artemisia capillaries inhibits LPS-activated iNOS , COX-2 , and HMGB 1 in RAW 264 . 7 cells

Jae Heun Lee, E. Park, Y. M. Kim, 2013 .

Propofol limits rat myocardial ischemia and reperfusion injury with an associated reduction in apoptotic cell death in vivo.

H. Seo, K. Chang, H. Kim, 2009, Vascular pharmacology.

Morin, a flavonoid from Moraceae, suppresses growth and invasion of the highly metastatic breast cancer cell line MDA-MB‑231 partly through suppression of the Akt pathway.

Soon-Chan Hong, Yung-Hyun Choi, Hyeon-soo Park, 2014, International journal of oncology.

P2Y2R activation by ATP induces oxLDL‐mediated inflammasome activation through modulation of mitochondrial damage in human endothelial cells

H. Kim, S. Park, Y. Ko, 2019, Free radical biology & medicine.

P2Y(2)R activation by nucleotides released from oxLDL-treated endothelial cells (ECs) mediates the interaction between ECs and immune cells through RAGE expression and reactive oxygen species production.

Jae Heun Lee, K. Chang, H. Kim, 2014, Free radical biology & medicine.

Genipin Selectively Inhibits TNF-α-activated VCAM-1 But Not ICAM-1 Expression by Upregulation of PPAR-γ in Human Endothelial Cells.

Jae Heun Lee, H. Seo, K. Chang, 2011, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.

Polyphenols from Artemisia annua L Inhibit Adhesion and EMT of Highly Metastatic Breast Cancer Cells MDA‐MB‐231

Yung-Hyun Choi, W. Lee, S. Shin, 2016, Phytotherapy research : PTR.

Abstract 1870: Polyphenols from Korean artemisia annua L (pKAL) showed anti-cancer effects by multiple mechanisms on HCT116 human colorectal cancer cells

W. Lee, S. Shin, G. Kim, 2019, Cancer Chemistry.

LPS potentiates nucleotide-induced inflammatory gene expression in macrophages via the upregulation of P2Y2 receptor.

Jae Heun Lee, K. Chang, H. Kim, 2014, International immunopharmacology.

Glycyrrhizin reduces HMGB1 secretion in lipopolysaccharide-activated RAW 264.7 cells and endotoxemic mice by p38/Nrf2-dependent induction of HO-1.

Y. M. Kim, K. Chang, H. Kim, 2015, International immunopharmacology.

Tanshinone I suppresses growth and invasion of human breast cancer cells, MDA-MB-231, through regulation of adhesion molecules.

Jae Heun Lee, Jong Sil Lee, H. Seo, 2008, Carcinogenesis.

231, through regulation of adhesion molecules.

Jae Heun Lee, Jong Sil Lee, H. Seo, 2008 .

Tanshinone I effectively induces apoptosis in estrogen receptor-positive (MCF-7) and estrogen receptor-negative (MDA-MB-231) breast cancer cells.

Jae Heun Lee, H. Seo, K. Chang, 2008, International journal of oncology.

Tanshinone IIA inhibits TNF-α-mediated induction of VCAM-1 but not ICAM-1 through the regulation of GATA-6 and IRF-1.

Jae Heun Lee, Y. M. Kim, K. Chang, 2012, International immunopharmacology.

Anthocyanins from the Fruit of Vitis Coignetiae Pulliat Inhibit TNF-Augmented Cancer Proliferation, Migration, and Invasion in A549 Cells

Soon-Chan Hong, Yung-Hyun Choi, W. Lee, 2017, Asian Pacific journal of cancer prevention : APJCP.

Paeonol and paeoniflorin, the main active principles of Paeonia albiflora, protect the heart from myocardial ischemia/reperfusion injury in rats.

Yong Chun Jin, Jae Heun Lee, H. Seo, 2008, Planta medica.

Hesperidin, hesperidin methyl chalone and phellopterin from Poncirus trifoliata (Rutaceae) differentially regulate the expression of adhesion molecules in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells.

K. Chang, H. Kim, Yeong Shik Kim, 2008, International immunopharmacology.

Radioresistant breast cancer cells exhibit increased resistance to chemotherapy and enhanced invasive properties due to cancer stem cells.

Jong Sil Lee, K. Chang, H. Kim, 2018, Oncology reports.

Identification of a truncated alternative splicing variant of human PPARgamma1 that exhibits dominant negative activity.

Jae Heun Lee, E. S. Kang, H. Seo, 2006, Biochemical and biophysical research communications.

Oleandrin and Its Derivative Odoroside A, Both Cardiac Glycosides, Exhibit Anticancer Effects by Inhibiting Invasion via Suppressing the STAT-3 Signaling Pathway

H. Kim, S. Park, Y. Ko, 2018, International journal of molecular sciences.

Expression of a Peroxisome Proliferator-Activated Receptor γ1 Splice Variant that Was Identified in Human Lung Cancers Suppresses Cell Death Induced by Cisplatin and Oxidative Stress

Jae Heun Lee, W. Choi, C. Yabe-Nishimura, 2007, Clinical Cancer Research.

HO-1 and JAK-2/STAT-1 signals are involved in preferential inhibition of iNOS over COX-2 gene expression by newly synthesized tetrahydroisoquinoline alkaloid, CKD712, in cells activated with lipopolysacchride.

Jae Heun Lee, Hee-Jeong Cho, K. Tsoyi, 2008, Cellular signalling.

Stimulation of alpha7 nicotinic acetylcholine receptor by nicotine attenuates inflammatory response in macrophages and improves survival in experimental model of sepsis through heme oxygenase-1 induction.

Jae Heun Lee, K. Tsoyi, H. Seo, 2011, Antioxidants & redox signaling.

P2Y2R activation by nucleotides released from the highly metastatic breast cancer cell contributes to pre-metastatic niche formation by mediating lysyl oxidase secretion, collagen crosslinking, and monocyte recruitment

K. Chang, H. Kim, S. Park, 2014, Oncotarget.

Honokiol exerts an anticancer effect in T98G human glioblastoma cells through the induction of apoptosis and the regulation of adhesion molecules.

Jae Heun Lee, K. Chang, H. Kim, 2012, International journal of oncology.

Anthocyanins from Vitis coignetiae Pulliat Inhibit Cancer Invasion and Epithelial-Mesenchymal Transition, but These Effects Can Be Attenuated by Tumor Necrosis Factor in Human Uterine Cervical Cancer HeLa Cells

Min Jeong Kim, Yung-Hyun Choi, W. Lee, 2013, Evidence-based complementary and alternative medicine : eCAM.

Radiotherapy-Resistant Breast Cancer Cells Enhance Tumor Progression by Enhancing Premetastatic Niche Formation through the HIF-1α-LOX Axis

H. Kim, Y. Ko, Hana Jin, 2020, International journal of molecular sciences.

NK Cells Lose Their Cytotoxicity Function against Cancer Stem Cell-Rich Radiotherapy-Resistant Breast Cancer Cell Populations

H. Kim, Hana Jin, H. J. Kim, 2021, International journal of molecular sciences.

P2Y2receptor activation by nucleotides released from highly metastatic breast cancer cells increases tumor growth and invasion via crosstalk with endothelial cells

Hana Jin, Jae Heun Lee, Jong Sil Lee, 2014, Breast Cancer Research.

Effect of Two Lipid Emulsions on Reversing High-Dose Levobupivacaine-Induced Reduced Vasoconstriction in the Rat Aortas

Seong Min Yang, H. Kim, Bo-Hwa Choi, 2013, Cardiovascular Toxicology.

Sugammadex reverses vecuronium-mediated inhibition of reactive oxygen species production in endothelial cells and vascular smooth muscle cells

H. Kim, Ji-Yon Kim, Y. Ko, 2020 .

Honokiol inhibits U87MG human glioblastoma cell invasion through endothelial cells by regulating membrane permeability and the epithelial-mesenchymal transition.

Jae Heun Lee, K. Chang, H. Kim, 2014, International journal of oncology.

TMEM14A inhibits N-(4-hydroxyphenyl)retinamide-induced apoptosis through the stabilization of mitochondrial membrane potential.

Hana Jin, Jae Heun Lee, W. Choi, 2011, Cancer letters.

Mepivacaine-induced contraction involves phosphorylation of extracellular signal-regulated kinase through activation of the lipoxygenase pathway in isolated rat aortic smooth muscle.

H. Kim, S. Ok, J. Sohn, 2013, Canadian journal of physiology and pharmacology.

Paeonol suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells by blocking p38, ERK and nuclear factor-kappaB signaling pathways.

K. Chang, H. Kim, Yeong Shik Kim, 2007, International immunopharmacology.

P2Y2R-mediated inflammasome activation is involved in tumor progression in breast cancer cells and in radiotherapy-resistant breast cancer

H. Kim, Y. Ko, Hana Jin, 2018, International journal of oncology.

The proximal tubular α7 nicotinic acetylcholine receptor attenuates ischemic acute kidney injury through Akt/PKC signaling-mediated HO-1 induction

K. Chang, H. Kim, S. Park, 2018, Experimental & Molecular Medicine.

The proximal tubular α7 nicotinic acetylcholine receptor attenuates ischemic acute kidney injury through Akt/PKC signaling-mediated HO-1 induction

K. Chang, H. Kim, S. Park, 2018, Experimental & Molecular Medicine.

Iron Released by Sodium Nitroprusside Contributes to Heme Oxygenase-1 Induction via the cAMP-Protein Kinase A-Mitogen-Activated Protein Kinase Pathway in RAW 264.7 Cells

Jae Heun Lee, H. Seo, K. Chang, 2006, Molecular Pharmacology.

Anticancer Effect of Benzimidazole Derivatives, Especially Mebendazole, on Triple-Negative Breast Cancer (TNBC) and Radiotherapy-Resistant TNBC In Vivo and In Vitro

H. Kim, Haa-Na Song, B. Jeong, 2021, Molecules.

Increased Extracellular Adenosine in Radiotherapy-Resistant Breast Cancer Cells Enhances Tumor Progression through A2AR-Akt-β-Catenin Signaling

H. Kim, Gyeong-Won Lee, Y. Ko, 2021, Cancers.

Polyphenols Extracted from Artemisia annua L. Exhibit Anti-Cancer Effects on Radio-Resistant MDA-MB-231 Human Breast Cancer Cells by Suppressing Stem Cell Phenotype, β-Catenin, and MMP-9

Soon-Chan Hong, E. Jung, W. Lee, 2020, Molecules.

MKP-7, a negative regulator of JNK, regulates VCAM-1 expression through IRF-1.

Jae Heun Lee, Y. M. Kim, K. Chang, 2012, Cellular signalling.

PTEN differentially regulates expressions of ICAM-1 and VCAM-1 through PI3K/Akt/GSK-3β/GATA-6 signaling pathways in TNF-α-activated human endothelial cells.

Jae Heun Lee, K. Tsoyi, Y. M. Kim, 2010, Atherosclerosis.

Bisacurone inhibits adhesion of inflammatory monocytes or cancer cells to endothelial cells through down-regulation of VCAM-1 expression.

Y. M. Kim, K. Chang, H. Kim, 2008, International immunopharmacology.

Protein kinase G-dependent heme oxygenase-1 induction by Agastache rugosa leaf extract protects RAW264.7 cells from hydrogen peroxide-induced injury.

Jae Heun Lee, H. Seo, K. Chang, 2006, Journal of ethnopharmacology.

Compound C independent of AMPK inhibits ICAM-1 and VCAM-1 expression in inflammatory stimulants-activated endothelial cells in vitro and in vivo.

Min Young Kim, Jae Heun Lee, G. Roh, 2011, Atherosclerosis.

P2Y2R has a significant correlation with Notch-4 in patients with breast cancer

Jong Sil Lee, H. Kim, Gyeong-Won Lee, 2020, Oncology letters.

Higenamine reduces apoptotic cell death by induction of heme oxygenase-1 in rat myocardial ischemia-reperfusion injury

Jae Heun Lee, H. Seo, K. Chang, 2006, Apoptosis.

Ethyl pyruvate inhibits the acetylation and release of HMGB1 via effects on SIRT1/STAT signaling in LPS-activated RAW264.7 cells and peritoneal macrophages.

E. Park, Y. M. Kim, K. Chang, 2016, International immunopharmacology.

The obligatory role of COX-2 expression for induction of HO-1 in ischemic preconditioned rat brain.

Jae Heun Lee, H. Seo, K. Chang, 2008, Biochemical and biophysical research communications.

Apoptotic Effects of Anthocyanins from Vitis coignetiae Pulliat Are Enhanced by Augmented Enhancer of the Rudimentary Homolog (ERH) in Human Gastric Carcinoma MKN28 Cells

Sangho Jeong, Young-Joon Lee, Soon-Chan Hong, 2021, International journal of molecular sciences.

Paroxetine Induces Apoptosis of Human Breast Cancer MCF-7 Cells through Ca2+-and p38 MAP Kinase-Dependent ROS Generation

K. Kang, H. Kim, Gyeong-Won Lee, 2019, Cancers.

DHA and EPA Down-regulate COX-2 Expression through Suppression of NF-kappaB Activity in LPS-treated Human Umbilical Vein Endothelial Cells.

W. Choi, W. Paik, K. Chang, 2009, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.

Aldose reductase in keratinocytes attenuates cellular apoptosis and senescence induced by UV radiation.

Jae Heun Lee, C. Yabe-Nishimura, E. S. Kang, 2011, Free radical biology & medicine.

Higenamine reduces HMGB1 during hypoxia-induced brain injury by induction of heme oxygenase-1 through PI3K/Akt/Nrf-2 signal pathways

Min Young Kim, Jae Heun Lee, Y. M. Kim, 2012, Apoptosis.

7,8-didehydrocimigenol from Cimicifugae rhizoma inhibits TNF-α-induced VCAM-1 but not ICAM-1expression through upregulation of PPAR-γ in human endothelial cells.

Jae Heun Lee, Y. M. Kim, H. Seo, 2011, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Honokiol activates the LKB1-AMPK signaling pathway and attenuates the lipid accumulation in hepatocytes.

K. Chang, H. Kim, S. Park, 2015, Toxicology and applied pharmacology.

Nobiletin ameliorates hepatic ischemia and reperfusion injury through the activation of SIRT-1/FOXO3a-mediated autophagy and mitochondrial biogenesis

S. Kim, H. Kim, S. Park, 2019, Experimental & Molecular Medicine.

Abscopal Effect of Radiotherapy Enhanced with Immune Checkpoint Inhibitors of Triple Negative Breast Cancer in 4T1 Mammary Carcinoma Model

H. Kim, Haa-Na Song, B. Jeong, 2021, International journal of molecular sciences.

13-Ethylberberine Induces Apoptosis through the Mitochondria-Related Apoptotic Pathway in Radiotherapy-Resistant Breast Cancer Cells

K. Chang, H. Kim, S. Park, 2019, Molecules.

Valsartan independent of AT1 receptor inhibits tissue factor, TLR-2 and-4 expression by regulation of Egr-1 through activation of AMPK in diabetic conditions

E. Park, K. Chang, H. Kim, 2014, Journal of cellular and molecular medicine.

Isoimperatorin, cimiside E and 23-O-acetylshengmanol-3-xyloside from Cimicifugae rhizome inhibit TNF-α-induced VCAM-1 expression in human endothelial cells: involvement of PPAR-γ upregulation and PI3K, ERK1/2, and PKC signal pathways.

Jae Heun Lee, Y. M. Kim, H. Seo, 2011, Journal of ethnopharmacology.

Fermentation of Sprouted Ginseng (Panax ginseng) Increases Flavonoid and Phenolic Contents to Attenuate Alcoholic Hangover and Acute Liver Injury in Mice.

S. Kim, E. Park, H. Kim, 2020, The American journal of Chinese medicine.

Ethanol Extract of Prunella vulgaris var. lilacina Inhibits HMGB1 Release by Induction of Heme Oxygenase‐1 in LPS‐activated RAW 264.7 Cells and CLP‐induced Septic Mice

Jae Heun Lee, E. Park, Y. M. Kim, 2012, Phytotherapy research : PTR.

Phorbol ester potentiates the growth inhibitory effects of troglitazone via up-regulation of PPARgamma in A549 cells.

Jae Heun Lee, E. S. Kang, H. Seo, 2006, Biochemical and biophysical research communications.

P2Y2 nucleotide receptor-mediated extracellular signal-regulated kinases and protein kinase C activation induces the invasion of highly metastatic breast cancer cells.

K. Chang, H. Kim, S. Park, 2015, Oncology reports.

P 2 Y 2 nucleotide receptor-mediated extracellular signal-regulated kinases and protein kinase C activation induces the invasion of highly metastatic breast cancer cells

K. Chang, H. Kim, S. Park, 2015 .

The Uremic Toxin Homocysteine Exacerbates the Brain Inflammation Induced by Renal Ischemia-Reperfusion in Mice

E. Park, H. Kim, S. Park, 2022, Biomedicines.

Kinetic Changes of COX-2 Expression during Reperfusion Period after Ischemic Preconditioning Play a Role in Protection Against Ischemic Damage in Rat Brain.

Jae Heun Lee, H. Seo, K. Chang, 2008, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.

Upregulation of PTEN by CKD712, a synthetic tetrahydroisoquinoline alkaloid, selectively inhibits lipopolysaccharide-induced VCAM-1 but not ICAM-1 expression in human endothelial cells.

Jae Heun Lee, K. Tsoyi, Y. M. Kim, 2009, Atherosclerosis.

P2Y2receptor activation by nucleotides released from highly metastatic breast cancer cells increases tumor growth and invasion via crosstalk with endothelial cells

Jae Heun Lee, K. Chang, H. Kim, 2014, Breast Cancer Research.

High concentrations of ascorbic acid induces apoptosis of human gastric cancer cell by p38-MAP kinase-dependent up-regulation of transferrin receptor.

Jae Heun Lee, H. Seo, K. Chang, 2009, Cancer letters.

Identification of Growth Factors, Cytokines and Mediators Regulated by Artemisia annua L. Polyphenols (pKAL) in HCT116 Colorectal Cancer Cells: TGF-β1 and NGF-β Attenuate pKAL-Induced Anticancer Effects via NF-κB p65 Upregulation

Soon-Chan Hong, E. Jung, W. Lee, 2022, International Journal of Molecular Sciences.

Polyphenols from Korean prostrate spurge Euphorbia supina induce apoptosis through the Fas-associated extrinsic pathway and activation of ERK in human leukemic U937 cells

Yung-Hyun Choi, A. Nagappan, W. Lee, 2016, Oncology reports.

Agastache rugosa leaf extract inhibits the iNOS expression in ROS 17/2.8 cells activated with TNF-α and IL-1β

Jae Heun Lee, E. S. Kang, H. Seo, 2005 .