H. Shim

M. Rojas, H. Shim, K. Brigham, 2008, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

Synthesis and evaluation of 2,5-furan, 2,5-thiophene and 3,4-thiophene-based derivatives as CXCR4 inhibitors.

H. Shim, Y. Oum, Zhongxing Liang, 2019, European journal of medicinal chemistry.

LPA 2 receptor mediates mitogenic signals in human colon cancer cells

Hong Sun, Raluca Rusovici, H. Shim, 2005 .

Lysophosphatidic Acid Facilitates Proliferation of Colon Cancer Cells via Induction of Krüppel-like Factor 5*

V. Yang, Raluca Rusovici, H. Shim, 2007, Journal of Biological Chemistry.

A benzenesulfonamide derivative as a novel PET radioligand for CXCR4.

M. Goodman, H. Shim, Y. Oum, 2019, Bioorganic & medicinal chemistry.

Anti-inflammatory hybrids of secondary amines and amide-sulfamide derivatives.

H. Shim, Y. Oum, Zhongxing Liang, 2018, European journal of medicinal chemistry.

Development of CXCR4 modulators by virtual HTS of a novel amide-sulfamide compound library.

H. Shim, C. Yun, Y. Oum, 2017, European journal of medicinal chemistry.

Benzenesulfonamides: A Unique Class of Chemokine Receptor Type 4 Inhibitors

J. Snyder, H. Shim, Zhongxing Liang, 2013, ChemMedChem.

Mapping early tumor response to radiotherapy using diffusion kurtosis imaging**

A. Maudsley, H. Shim, E. Mellon, 2022, The neuroradiology journal.

Targeting tissue factor-expressing tumor angiogenesis and tumors with EF24 conjugated to factor VIIa.

J. Snyder, W. Kisiel, H. Shim, 2008, Journal of drug targeting.

Metabolic PET Imaging in Cancer Detection and Therapy Response

H. Shim, Aizhi Zhu, Daniel Lee, 2011 .

Final Report on Clinical Outcomes and Tumor Recurrence Patterns of a Pilot Study Assessing Efficacy of Belinostat (PXD-101) with Chemoradiation for Newly Diagnosed Glioblastoma

J. Olson, P. Barker, H. Shu, 2021, Tomography.

Development of CXCR4 modulators based on the lead compound RB-108.

H. Shim, Y. Oum, Zhongxing Liang, 2019, European journal of medicinal chemistry.

Novel anti-inflammatory agents targeting CXCR4: Design, synthesis, biological evaluation and preliminary pharmacokinetic study.

H. Shim, Zhongxing Liang, Y. Yoon, 2017, European journal of medicinal chemistry.

Presentation of treatment effect in glioblastoma after dose-escalation radiation therapy

J. Olson, B. Weinberg, H. Shim, 2019, Oxford medical case reports.

Early prediction of response to Vorinostat in an orthotopic glioma rat model

Scott N. Hwang, J. Olson, H. Shim, 2022 .

MicroRNA-302 Replacement Therapy Sensitizes Breast Cancer Cells to Ionizing Radiation

J. Votaw, H. Shim, Zhongxing Liang, 2013, Pharmaceutical Research.

Magnetic resonance spectroscopic imaging in the era of pseudoprogression and pseudoresponse in glioblastoma patient management.

J. Olson, C. Holder, H. Shim, 2013, CNS oncology.

Discovery of novel aminopiperidinyl amide CXCR4 modulators through virtual screening and rational drug design.

H. Shim, Y. Oum, Zhongxing Liang, 2020, European journal of medicinal chemistry.

Discovery of small molecule CXCR4 antagonists.

Hyunsuk Shim, James P Snyder, Dennis C Liotta, 2007, Journal of medicinal chemistry.

Eliminating the Heart from the Curcumin Molecule: Monocarbonyl Curcumin Mimics (MACs)

J. Snyder, H. Shim, Dinesh Shetty, 2014, Molecules.

Inhibition of Breast Cancer Metastasis by Selective Synthetic Polypeptide against CXCR4

S. Nie, R. Taichman, H. Shim, 2004, Cancer Research.

Deletion of Na+/H+ exchanger regulatory factor 2 represses colon cancer progress by suppression of Stat3 and CD24.

G. Grigoryan, H. Shim, C. Yun, 2016, American journal of physiology. Gastrointestinal and liver physiology.

Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism.

Hyunsuk Shim, Zhaobin Zhang, Daniel J Brat, 2009, Cancer research.

Regulation of Hypoxia-inducible Factor 1α (HIF-1α) by Lysophosphatidic Acid Is Dependent on Interplay between p53 and Krüppel-like Factor 5*

D. Dang, V. Yang, H. Shim, 2013, The Journal of Biological Chemistry.

The absence of LPA receptor 2 reduces the tumorigenesis by ApcMin mutation in the intestine.

J. Chun, H. Shim, C. Yun, 2010, American journal of physiology. Gastrointestinal and liver physiology.

mutation in the intestine MinApc tumorigenesis by The absence of LPA receptor 2 reduces the

J. Chun, H. Shim, C. Yun, 2010 .

Silencing of CXCR4 blocks breast cancer metastasis.

J. Votaw, M. Goodman, H. Shim, 2005, Cancer research.

CXC chemokine receptor-4 antagonist blocks both growth of primary tumor and metastasis of head and neck cancer in xenograft mouse models.

Z. Chen, D. Shin, M. Goodman, 2007, Cancer research.

Silencing of CXCR 4 Blocks Breast Cancer Metastasis

J. Votaw, M. Goodman, H. Shim, 2005 .

Potential Biomarker of L-type Amino Acid Transporter 1 in Breast Cancer Progression

M. Goodman, K. Liang, H. Shim, 2011, Nuclear medicine and molecular imaging.

The absence of LPA2 attenuates tumor formation in an experimental model of colitis-associated cancer.

J. Chun, V. Yang, A. Ghaleb, 2009, Gastroenterology.

Chemokine receptor CXCR4 as a therapeutic target for neuroectodermal tumors.

H. Shim, N. Fujii, S. Oishi, 2009, Seminars in cancer biology.

Targeting CXCR4 in Brain Tumors

H. Shim, 2009 .

Stroma Targeting Nuclear Imaging and Radiopharmaceuticals

H. Shim, J. Jeong, Dinesh Shetty, 2012, International journal of molecular imaging.

HDAC inhibitor suppresses proliferation and invasion of breast cancer cells through regulation of miR‐200c targeting CRKL

H. Shim, Zhongxing Liang, Xue-Hai Bian, 2018, Biochemical pharmacology.

MicroRNA-30c-regulated HDAC9 mediates chemoresistance of breast cancer

H. Shim, Zhongxing Liang, Amber Feng, 2020, Cancer Chemotherapy and Pharmacology.

Regulation of miR-19 to Breast Cancer Chemoresistance Through Targeting PTEN

Hyunsuk Shim, Ke Huang, Zhongxing Liang, 2011, Pharmaceutical Research.

Regulation of Hypoxia-inducible Factor 1 alpha (HIF-1 alpha) by Lysophosphatidic Acid Is Dependent on Interplay between p53 and Kruppel-like Factor 5

D. Dang, V. Yang, H. Shim, 2022 .

The Role of Standard and Advanced Imaging for the Management of Brain Malignancies From a Radiation Oncology Standpoint.

H. Shu, B. Weinberg, H. Shim, 2018, Neurosurgery.

A Systematic Pipeline for the Objective Comparison of Whole-Brain Spectroscopic MRI with Histology in Biopsy Specimens from Grade 3 Glioma

Eduard Schreibmann, Lee A. D. Cooper, Hyunsuk Shim, 2016, Tomography.

Semi-Automated Volumetric and Morphological Assessment of Glioblastoma Resection with Fluorescence-Guided Surgery

Eduard Schreibmann, Hyunsuk Shim, Ying Guo, 2016, Molecular Imaging and Biology.

Development of a Unique Small Molecule Modulator of CXCR4

J. Snyder, H. Grossniklaus, M. Goodman, 2012, PloS one.

Use of high-resolution volumetric MR spectroscopic imaging in assessing treatment response of glioblastoma to an HDAC inhibitor.

Hyunsuk Shim, Ying Guo, Chad A Holder, 2014, AJR. American journal of roentgenology.

Cancer scene investigation: how a cold virus became a tumor killer.

Hyunsuk Shim, Erwin G. Van Meir, H. Shim, 2005, Future oncology.

A Novel Approach to Determining Tumor Progression Using a Three-Site Pilot Clinical Trial of Spectroscopic MRI-Guided Radiation Dose Escalation in Glioblastoma

P. Barker, H. Shu, E. Schreibmann, 2023, Tomography.

A multi-institutional pilot clinical trial of spectroscopic MRI-guided radiation dose escalation for newly diagnosed glioblastoma

P. Barker, A. Maudsley, H. Shu, 2022, Neuro-oncology advances.

Spectroscopic MRI for Brain Tumor Imaging

H. Shim, 2021, Molecular Imaging.

The Brain Imaging Collaboration Suite (BrICS): A Cloud Platform for Integrating Whole-Brain Spectroscopic MRI into the Radiation Therapy Planning Workflow

Eduard Schreibmann, Andrew Maudsley, Hui-Kuo Shu, 2019, Tomography.

Assessing Treatment Response of Glioblastoma to an HDAC Inhibitor Using Whole-Brain Spectroscopic MRI

J. Olson, José E. Velázquez Vega, H. Shu, 2019, Tomography.

The role of erlotinib and the Optune device in a patient with an epidermal growth factor receptor viii amplified glioblastoma

J. Olson, H. Shu, H. Shim, 2018, Oxford medical case reports.

Whole-brain spectroscopic MRI biomarkers identify infiltrating margins in glioblastoma patients.

Eduard Schreibmann, Hyunsuk Shim, James S Cordova, 2016, Neuro-oncology.

Quantitative tumor segmentation for evaluation of extent of glioblastoma resection to facilitate multisite clinical trials.

Eduard Schreibmann, Hyunsuk Shim, James S Cordova, 2014, Translational oncology.

Spectroscopic MRI-Guided Proton Therapy in Non-Enhancing Pediatric High-Grade Glioma

Abinand C. Rejimon, H. Shim, B. Eaton, 2023, Tomography.

MRI-based attenuation correction for brain PET/MRI based on anatomic signature and machine learning

Yang Lei, Walter J Curran, Xiaofeng Yang, 2019, Physics in medicine and biology.

High-resolution CT image retrieval using sparse convolutional neural network

Tian Liu, Dong Xu, Yang Lei, 2018, Medical Imaging.

MicroRNA-302 Replacement Therapy Sensitizes Breast Cancer Cells to Ionizing Radiation

J. Votaw, H. Shim, Zhongxing Liang, 2012, Pharmaceutical Research.

Current Molecular Imaging Positron Emitting Radiotracers in Oncology

H. Shim, Aizhi Zhu, 2011, Nuclear medicine and molecular imaging.

Dipyrimidine amines: a novel class of chemokine receptor type 4 antagonists with high specificity.

J. Snyder, H. Grossniklaus, H. Shim, 2010, Journal of medicinal chemistry.

Clinical Applications of Magnetic Resonance Spectroscopy in Brain Tumors: From Diagnosis to Treatment.

M. Mullins, B. Weinberg, H. Shim, 2021, Radiologic clinics of North America.

Alimentary Tract

H. Shim, C. Yun, Sei-Jung Lee, 2022 .

Synthesis and evaluation of 2,5-diamino and 2,5-dianilinomethyl pyridine analogues as potential CXCR4 antagonists.

H. Shim, Zhongxing Liang, Y. Yoon, 2019, Bioorganic & medicinal chemistry letters.

Inhibition of breast cancer metastasis with microRNA-302a by downregulation of CXCR4 expression

H. Shim, Zhongxing Liang, Xue-Hai Bian, 2014, Breast Cancer Research and Treatment.

Magnetic Resonance Spectroscopic Imaging of Tumor Metabolic Markers for Cancer Diagnosis, Metabolic Phenotyping, and Characterization of Tumor Microenvironment

Hyunsuk Shim, Douglas L. Rothman, Dikoma C. Shungu, 2004, Disease markers.

Magnetic resonance imaging-based pseudo computed tomography using anatomic signature and joint dictionary learning

Tian Liu, Yang Lei, Sibo Tian, 2018, Journal of medical imaging.

HDAC9 overexpression confers invasive and angiogenic potential to triple negative breast cancer cells via modulating microRNA-206.

H. Shim, Zhongxing Liang, Xue-Hai Bian, 2018, Biochemical and biophysical research communications.

LPA2 receptor mediates mitogenic signals in human colon cancer cells.

Hyunsuk Shim, Hong Sun, Raluca Rusovici, 2005, American journal of physiology. Cell physiology.

MRI-based pseudo CT synthesis using anatomical signature and alternating random forest with iterative refinement model

Tian Liu, Yang Lei, Sibo Tian, 2018, Journal of medical imaging.

3D whole-brain metabolite imaging to improve characterization of low-to-intermediate grade gliomas

J. Olson, H. Shu, E. Schreibmann, 2021, Journal of Neuro-Oncology.

Synthesis of pyridine derivatives as potential antagonists of chemokine receptor type 4

H. Shim, Zhongxing Liang, S. Mooring, 2014, Heterocyclic communications.

Letter to cancer center directors: Progress in quantitative imaging as a means to predict and/or measure tumor response in cancer therapy trials.

Paul E Kinahan, Thomas E Yankeelov, John M Buatti, 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

MRI-based synthetic CT generation using deep convolutional neural network

Yang Lei, Sibo Tian, Tian Liu, 2019, Medical Imaging: Image Processing.

Attenuation and Scatter Correction for Whole-body PET Using 3D Generative Adversarial Networks

Yang Lei, Xiaofeng Yang, Hui Mao, 2019 .

Incorporation of a spectral model in a convolutional neural network for accelerated spectral fitting

Andrew A Maudsley, Hyunsuk Shim, Sulaiman Sheriff, 2019, Magnetic resonance in medicine.

Amide-sulfamide modulators as effective anti-tumor metastatic agents targeting CXCR4/CXCL12 axis.

H. Shim, Zhongxing Liang, Y. Yoon, 2019, European journal of medicinal chemistry.

Mutant Isocitrate Dehydrogenase 1 Expression Enhances Response of Gliomas to the Histone Deacetylase Inhibitor Belinostat

B. Weinberg, H. Shim, H. Shu, 2023, Tomography.

Remarkable response of a patient with secondary glioblastoma to a histone deacetylase inhibitor

J. Olson, José E. Velázquez Vega, H. Shu, 2020, Oxford medical case reports.

Simulating the Effect of Spectroscopic MRI as a Metric for Radiation Therapy Planning in Patients with Glioblastoma

Eduard Schreibmann, Hui-Kuo Shu, Hyunsuk Shim, 2016, Tomography.

Spectroscopic MRI-Based Biomarkers Predict Survival for Newly Diagnosed Glioblastoma in a Clinical Trial

P. Barker, H. Shu, B. Weinberg, 2023, Cancers.

Applying a Radiation Therapy Volume Analysis Pipeline to Determine the Utility of Spectroscopic MRI-Guided Adaptive Radiation Therapy for Glioblastoma

P. Barker, H. Shu, E. Schreibmann, 2023, Tomography.

Radiosensitization of glioma cells with the curcumin analogs EF24 and EF31

J. Snyder, H. Shu, H. Shim, 2008 .

Blockade of invasion and metastasis of breast cancer cells via targeting CXCR4 with an artificial microRNA.

H. Shim, Zhongxing Liang, Y. Yoon, 2007, Biochemical and biophysical research communications.

A Fully Automated Post-Surgical Brain Tumor Segmentation Model for Radiation Treatment Planning and Longitudinal Tracking

H. Shu, B. Weinberg, H. Shim, 2023, Cancers.

Pseudo CT estimation from MRI using patch-based random forest

Yang Lei, Tian Liu, Xiaofeng Yang, 2017, Medical Imaging.

NIMG-23. BRAIN TUMOR REPORTING AND DATA SYSTEM (BT-RADS) AND QUANTITATIVE TOOLS TO GUIDE ITS IMPLEMENTATION

H. Shu, E. Schreibmann, B. Weinberg, 2019, Neuro-Oncology.

A convolutional neural network to filter artifacts in spectroscopic MRI

Eduard Schreibmann, Peter B Barker, Andrew A Maudsley, 2018, Magnetic resonance in medicine.

MAGI-3 competes with NHERF-2 to negatively regulate LPA2 receptor signaling in colon cancer cells

H. Shim, C. Yun, Sei-Jung Lee, 2022 .

The Use of Quantitative Imaging in Radiation Oncology: A Quantitative Imaging Network (QIN) Perspective.

Paul Kinahan, P. Lambin, D. Mankoff, 2018, International journal of radiation oncology, biology, physics.

Chemokine receptor CXCR4 as a therapeutic target for neuroectodermal tumors.

H. Shim, N. Fujii, S. Oishi, 2009, Seminars in cancer biology.

Simulating the Effect of Spectroscopic MRI as a Metric for Radiation Therapy Planning in Patients with Glioblastoma

C. Holder, H. Shu, E. Schreibmann, 2016, Tomography.

Deletion of Na+/H+ exchanger regulatory factor 2 represses colon cancer progress by suppression of Stat3 and CD24.

G. Grigoryan, H. Shim, C. Yun, 2016, American journal of physiology. Gastrointestinal and liver physiology.

Attenuation of obliterative bronchiolitis by a CXCR4 antagonist in the murine heterotopic tracheal transplant model.

M. Rojas, H. Shim, K. Brigham, 2008, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

Improving image quality of cone-beam CT using alternating regression forest

Tian Liu, Yang Lei, Xiaofeng Yang, 2018, Medical Imaging.

Letter to cancer center directors: Progress in quantitative imaging as a means to predict and/or measure tumor response in cancer therapy trials.

Paul Kinahan, T. Yankeelov, D. Mankoff, 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.