N. Purcell

发表

MEK1-ERK2 Signaling Pathway Protects Myocardium From Ischemic Injury In Vivo

P. Doevendans, J. Pouysségur, S. Meloche, 2004, Circulation.

Inhibition of JNK activation through NF-kappaB target genes.

M. Karin, Y. Minemoto, A. Lin, 2001, Nature.

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

Jeffrey Robbins, Gerald W. Dorn, G. Dorn, 2005, Nature.

Extracellular Signal-Regulated Kinase 2 Interacts with and Is Negatively Regulated by the LIM-Only Protein FHL2 in Cardiomyocytes

R. Schüle, J. Molkentin, O. Bueno, 2004, Molecular and Cellular Biology.

Activation of nuclear factor- B is necessary for myotrophin-induced cardiac hypertrophy

A. Lin, N. Purcell, Sudhiranjan Gupta, 2002 .

Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo

S. Meloche, J. Molkentin, B. Wilkins, 2007, Proceedings of the National Academy of Sciences.

Selective coupling of the S1P3 receptor subtype to S1P-mediated RhoA activation and cardioprotection.

J. Chun, S. Miyamoto, N. Purcell, 2017, Journal of molecular and cellular cardiology.

Sphingosine 1-phosphate receptor 3 and RhoA signaling mediate inflammatory gene expression in astrocytes

J. Chun, N. Purcell, H. Rosen, 2017, Journal of Neuroinflammation.

Ca2+/Calmodulin-Dependent Protein Kinase II &dgr; Mediates Myocardial Ischemia/Reperfusion Injury Through Nuclear Factor-&kgr;B

Yusu Gu, N. Dalton, K. Peterson, 2013, Circulation research.

Phospholipase Cɛ links G protein-coupled receptor activation to inflammatory astrocytic responses

E. Masliah, E. Rockenstein, N. Purcell, 2013, Proceedings of the National Academy of Sciences.

RhoA protects the mouse heart against ischemia/reperfusion injury.

G. Dorn, R. Lang, S. Miyamoto, 2011, The Journal of clinical investigation.

Sphingosine 1-phosphate elicits RhoA-dependent proliferation and MRTF-A mediated gene induction in CPCs.

Mark A Sussman, N. Purcell, J. Brown, 2016, Cellular signalling.

Activation of NF-κB by hepatitis B virus X protein through an IκB kinase-independent mechanism

N. Paran, Y. Shaul, S. Yamaoka, 2001 .

Activation of nuclear factor- (cid:2) B is necessary for myotrophin-induced cardiac hypertrophy

A. Lin, N. Purcell, Sudhiranjan Gupta, 2002 .

Inhibition of JNK activation through NF-κB target genes

M. Karin, Y. Minemoto, A. Lin, 2001, Nature.

Mechanisms and Models for Elucidating the Cardiac Effects of Sphingosine 1‐Phosphate (S1P)

S. Miyamoto, N. Purcell, J. Brown, 2013 .

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

G. Dorn, R. Gottlieb, J. Molkentin, 2022 .

DUSP6 (MKP3) Null Mice Show Enhanced ERK1/2 Phosphorylation at Baseline and Increased Myocyte Proliferation in the Heart Affecting Disease Susceptibility*

J. Molkentin, O. Bueno, N. Purcell, 2008, Journal of Biological Chemistry.

Activation of NF-κB is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes

A. Lin, F. Mercurio, N. Purcell, 2001, Proceedings of the National Academy of Sciences of the United States of America.

mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2

KyeongJin Kim, L. Qiang, M. Hayden, 2016, Nature Communications.

Collagen XIV is important for growth and structural integrity of the myocardium.

N. Purcell, J. Lincoln, M. Koch, 2012, Journal of molecular and cellular cardiology.

APJ ACTS AS A DUAL RECEPTOR IN CARDIAC HYPERTROPHY

E. Ashley, D. Catalucci, R. Bodmer, 2012, Nature.

Is nuclear factor kappaB an attractive therapeutic target for treating cardiac hypertrophy?

J. Molkentin, N. Purcell, Nicole H Purcell, 2003, Circulation.

PHLPP-1 Negatively Regulates Akt Activity and Survival in the Heart

A. Newton, Mark A Sussman, S. Miyamoto, 2010, Circulation research.

Physiological activation of Akt by PHLPP1 deletion protects against pathological hypertrophy.

Xiaoxue Zhang, Å. Gustafsson, N. Purcell, 2015, Cardiovascular research.

UNIVERSITY OF CALIFORNIA, SAN DIEGO Effects of PHLPP1 Removal in the Heart A Thesis submitted in partial satisfaction of the requirements for the degree Master of Science in Biology By Courtney Moc Committee in charge:

N. Purcell, Nicole H. Purcell, 2015 .

PH domain leucine-rich repeat protein phosphatase 2 (PHLPP2) regulates G-protein–coupled receptor kinase 5 (GRK5)-induced cardiac hypertrophy in vitro

W. Koch, N. Purcell, Cristina M Zambrano, 2018, The Journal of Biological Chemistry.

PHLPP1 Gene Deletion Protects the Brain from Ischemic Injury

N. Purcell, P. Lyden, J. Brown, 2013, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

PHLPP2 Negatively Regulates Phenylephrine (PE)- induced Cardiac Hypertrophy

N. Purcell, 2017 .

Decline in cellular function of aged mouse c‐kit+ cardiac progenitor cells

Å. Gustafsson, N. Purcell, Amabel M. Orogo, 2017, The Journal of physiology.

Sphingosine 1-phosphate elicits RhoA-dependent proliferation and MRTF-A mediated gene induction in CPCs.

Mark A Sussman, N. Purcell, J. Brown, 2016, Cellular signalling.

CaMKII δ Mediates Myocardial Ischemia/Reperfusion Injury Through NF-κ B

N. Dalton, N. Purcell, Haiyun Ling, 2013 .