R. A. Kaiser

发表

MEK1-ERK2 Signaling Pathway Protects Myocardium From Ischemic Injury In Vivo

P. Doevendans, J. Pouysségur, S. Meloche, 2004, Circulation.

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

Jeffrey Robbins, Gerald W. Dorn, G. Dorn, 2005, Nature.

Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc.

P. Caroni, H. Drexler, J. Molkentin, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of p38 reduces myocardial infarction injury in the mouse but not pig after ischemia-reperfusion.

J. Molkentin, R. A. Kaiser, J. Pearl, 2005, American journal of physiology. Heart and circulatory physiology.

Genetic Manipulation of Periostin Expression Reveals a Role in Cardiac Hypertrophy and Ventricular Remodeling

G. Dorn, B. Aronow, J. Molkentin, 2007, Circulation research.

Inducible and myocyte-specific inhibition of PKCalpha enhances cardiac contractility and protects against infarction-induced heart failure.

J. Molkentin, J. Lorenz, R. A. Kaiser, 2007, American journal of physiology. Heart and circulatory physiology.

Genetic Manipulation of Periostin Expression Reveals a Role in Cardiac Hypertrophy and Ventricular Remodeling

G. Dorn, B. Aronow, J. Molkentin, 2007 .

Functional Compartmentation of Endothelial P2Y Receptor Signaling

R. A. Kaiser, B. C. Oxhorn, I. Buxton, 2002, Circulation research.

Targeted Inhibition of p38 Mitogen-activated Protein Kinase Antagonizes Cardiac Injury and Cell Death Following Ischemia-Reperfusion in Vivo*

P. Doevendans, D. Lips, J. Molkentin, 2004, Journal of Biological Chemistry.

Genetic Inhibition or Activation of JNK1/2 Protects the Myocardium from Ischemia-Reperfusion-induced Cell Death in Vivo*

T. Hewett, J. Molkentin, O. Bueno, 2005, Journal of Biological Chemistry.

Nucleotides in the blood stream.

R. A. Kaiser, I. Buxton, 2004, Proceedings of the Western Pharmacology Society.

Inhibition of p 38 reduces myocardial infarction injury in the mouse but not pig after ischemia-reperfusion

J. Molkentin, R. A. Kaiser, J. Pearl, 2005 .

Comparison of BNT162b2 (Pfizer–BioNtech) and mRNA-1273 (Moderna) SARS-CoV-2 mRNA vaccine immunogenicity in dialysis patients

R. A. Kaiser, M. Haller, P. Apfalter, 2021, Kidney International.

Evidence supporting the Nucleotide Axis Hypothesis: ATP release and metabolism by coronary endothelium.

R. A. Kaiser, B. C. Oxhorn, I. Buxton, 2001, American journal of physiology. Heart and circulatory physiology.

Nucleotide‐mediated relaxation in guinea‐pig aorta: selective inhibition by MRS2179

R. A. Kaiser, I. Buxton, 2002, British journal of pharmacology.

Use of an adeno‐associated virus serotype Anc80 to provide durable cure of phenylketonuria in a mouse model

R. A. Kaiser, A. Douar, G. González-Aseguinolaza, 2021, Journal of inherited metabolic disease.

Use of an AAV serotype Anc80 to provide durable cure of phenylketonuria in a mouse model

R. A. Kaiser, A. Douar, L. Trigueros-Motos, 2021 .

The future of gene-targeted therapy for hereditary tyrosinemia type 1 as a lead indication among the inborn errors of metabolism

R. A. Kaiser, J. Lillegard, Gourish Mondal, 2020, Expert opinion on orphan drugs.

Development of a porcine model of phenylketonuria with a humanized R408W mutation for gene editing

D. F. Carlson, A. Watson, R. A. Kaiser, 2021, PloS one.

Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death

W. Craigen, J. Molkentin, R. A. Kaiser, 2007, Nature Cell Biology.

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

G. Dorn, R. Gottlieb, J. Molkentin, 2022 .

In vivo lentiviral vector gene therapy to cure hereditary tyrosinemia type 1 and prevent development of precancerous and cancerous lesions

J. Kocher, D. O'Brien, S. Russell, 2021, Nature Communications.

Ex Vivo Hepatocyte Reprograming Promotes Homology‐Directed DNA Repair to Correct Metabolic Disease in Mice After Transplantation

S. Nyberg, R. A. Kaiser, Yuanhang Liu, 2019, Hepatology communications.

Autologous Gene and Cell Therapy Provides Safe and Long-Term Curative Therapy in A Large Pig Model of Hereditary Tyrosinemia Type 1

S. Nyberg, R. A. Kaiser, C. Harding, 2018, Cell transplantation.

Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo.

P. Pfluger, E. van Rooij, J. Molkentin, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Activation of homology-directed DNA repair plays key role in CRISPR-mediated genome correction

J. Kocher, R. A. Kaiser, W. Cao, 2022, Gene Therapy.

Calcineurin A &bgr; Gene Targeting Predisposes the Myocardium to Acute Ischemia-Induced Apoptosis and Dysfunction

T. Hewett, P. Doevendans, B. Aronow, 2004, Circulation research.

Comparison of mRNA-1273 and BNT162b2 SARS-CoV-2 mRNA Vaccine Immunogenicity in Kidney Transplant Recipients

R. A. Kaiser, M. Haller, P. Apfalter, 2022, Transplant International.

Ex Vivo Cell Therapy by Ectopic Hepatocyte Transplantation Treats the Porcine Tyrosinemia Model of Acute Liver Failure

V. Lowe, J. Kocher, S. Nyberg, 2020, Molecular therapy. Methods & clinical development.

Ectopic hepatocyte transplantation cures the pig model of tyrosinemia

V. Lowe, J. Kocher, S. Nyberg, 2019, bioRxiv.

Hepatotoxicity and Toxicology of In Vivo Lentiviral Vector Administration in Healthy and Liver-Injury Mouse Models.

R. A. Kaiser, J. Lillegard, Clara T. Nicolas, 2019, Human gene therapy. Clinical development.

Hepatocyte spheroids as an alternative to single cells for transplantation after ex vivo gene therapy in mice and pig models

S. Nyberg, Aditya Bansal, M. Pandey, 2018, Surgery.