D. Ito

发表

Activation of ERK 1 2 is associated with Neuronal Survival after Focal Cerebral Ischemia in the Rat

E. Nagata, Kortaro Tanaka, A. Kosakai, 2004 .

Phosphorylation of Cyclic Adenosine Monophosphate Response Element Binding Protein in Oligodendrocytes in the Corpus Callosum after Focal Cerebral Ischemia in the Rat

Kortaro Tanaka, Y. Fukuuchi, A. Kosakai, 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Cyclic AMP Response Element Binding Protein Phosphorylation May Be Closely Associated with Neuroprotective Mechanisms After Focal Ischemia in Rat Brain

Y. Fukuuchi, A. Kosakai, S. Nogawa, 2001 .

Activated phosphorylation of cyclic AMP response element binding protein is associated with preservation of striatal neurons after focal cerebral ischemia in the rat

Kortaro Tanaka, Y. Fukuuchi, A. Kosakai, 2000, Neuroscience.

Characterization of seipin/BSCL2, a protein associated with spastic paraplegia 17

D. Ito, N. Suzuki, T. Fujisawa, 2008, Neurobiology of Disease.

Evidence of TRK-Fused Gene (TFG1) function in the ubiquitin–proteasome system

D. Ito, N. Suzuki, T. Yagi, 2014, Neurobiology of Disease.

D. Ito, N. Suzuki, T. Yagi, 2016, Journal of neuropathology and experimental neurology.

The human lipodystrophy protein seipin is an ER membrane adaptor for the adipogenic PA phosphatase lipin 1.

S. O’Rahilly, V. Saudek, D. Ito, 2013, Molecular metabolism.

Randomized double‐blind placebo‐controlled multicenter trial of Yokukansan for neuropsychiatric symptoms in Alzheimer's disease

N. Araki, Satoshi Takahashi, H. Yonezawa, 2017, Geriatrics & gerontology international.

RNA binding proteins and the pathological cascade in ALS/FTD neurodegeneration

D. Ito, N. Suzuki, M. Hatano, 2017, Science Translational Medicine.

Roles of Ataxin-2 in Pathological Cascades Mediated by TAR DNA-binding Protein 43 (TDP-43) and Fused in Sarcoma (FUS)*

D. Ito, N. Suzuki, Y. Nihei, 2012, The Journal of Biological Chemistry.

[Conjoint pathological cascades mediated by RNA-binding proteins, TDP-43, FUS and ataxin-2].

D. Ito, 2012, Rinsho shinkeigaku = Clinical neurology.

The DNA damage response (DDR) is induced by the C9orf72 repeat expansion in amyotrophic lateral sclerosis

D. Ito, A. Konopka, J. Atkin, 2017, Human molecular genetics.

Impact of a combination of quantitative indices representing uptake intensity, shape, and asymmetry in DAT SPECT using machine learning: comparison of different volume of interest settings

M. Jinzaki, M. Kameyama, D. Ito, 2019, EJNMMI Research.

Stanniocalcin 2 Is a Negative Modulator of Store-Operated Calcium Entry

D. Ito, M. Oh‐hora, M. Villereal, 2011, Molecular and Cellular Biology.

Molecular pathogenesis of seipin/BSCL2‐related motor neuron diseases

D. Ito, N. Suzuki, 2007, Annals of neurology.

C242T polymorphism of NADPH oxidase p22 PHOX gene and ischemic cerebrovascular disease in the Japanese population.

Y. Fukuuchi, D. Ito, M. Murata, 2000, Stroke.

Polymorphism of NADPH Oxidase p 22 PHOX Gene and Ischemic Cerebrovascular Disease in the Japanese Population

Y. Fukuuchi, D. Ito, M. Murata, 2000 .

Postischemic Hyperperfusion Does Not Necessarily Indicate Good Recovery of Brain Tissue. From the Viewpoint of PKA-Mediated Intracellular Signal Transduction

E. Nagata, Kortaro Tanaka, Y. Fukuuchi, 2001 .

Nuclear transport impairment of amyotrophic lateral sclerosis‐linked mutations in FUS/TLS

D. Ito, N. Suzuki, M. Seki, 2011, Annals of neurology.

Degeneration of mesencephalic dopaminergic neurons in klotho mouse related to vitamin D exposure

Y. Okada, A. Kosakai, D. Ito, 2011, Brain Research.

N88S seipin mutant transgenic mice develop features of seipinopathy/BSCL2-related motor neuron disease via endoplasmic reticulum stress.

D. Ito, N. Suzuki, T. Yagi, 2011, Human molecular genetics.

N 88 S seipin mutant transgenic mice develop features of seipinopathy / BSCL 2-related motor neuron disease via endoplasmic reticulum stress

D. Ito, N. Suzuki, T. Yagi, 2011 .

Up-regulation of the Ire1-mediated signaling molecule, Bip, in ischemic rat brain

Kortaro Tanaka, Y. Fukuuchi, A. Kosakai, 2001, Neuroreport.

Can we predict amyloid deposition by objective cognition and regional cerebral blood flow in patients with subjective cognitive decline?

M. Jinzaki, M. Mimura, M. Kameyama, 2019, Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society.

Polymorphism in the Promoter of Lipopolysaccharide Receptor CD14 and Ischemic Cerebrovascular Disease

Y. Fukuuchi, D. Ito, M. Murata, 2000, Stroke.

Extremely Low Prevalence of Amyloid Positron Emission Tomography Positivity in Parkinson's Disease without Dementia

M. Jinzaki, M. Kameyama, D. Ito, 2017, European Neurology.

Association between platelet glycoprotein Ibalpha genotype and ischemic cerebrovascular disease.

Masahiro Yamamoto, Y. Fukuuchi, D. Ito, 2000, Stroke.

Findings of 18F‐PI‐2620 tau PET imaging in patients with Alzheimer’s disease and healthy controls in relation to the plasma P‐tau181 levels in a Japanese sample

R. Ueda, S. Nakajima, Masaru Mimura, 2022, Neuropsychopharmacology reports.

Alteration of Control Mechanisms of Endoplasmic Reticulum Calcium Pools in Focal Cerebral Ischemia

A. Futatsugi, E. Nagata, D. Ito, 1999 .

[Modeling familial Alzheimer's disease with induced pluripotent stem cells].

H. Okano, D. Ito, N. Suzuki, 2012, Rinsho shinkeigaku = Clinical neurology.

Extensive splicing changes in an ALS/FTD transgenic mouse model overexpressing cytoplasmic fused in sarcoma

D. Ito, Ryota Taguchi, E. Inoue, 2020, Scientific Reports.

De novo design of RNA-binding proteins with a prion-like domain related to ALS/FTD proteinopathies

D. Ito, N. Suzuki, K. Mashima, 2017, Scientific Reports.

A novel voltage-sensitive Na+ and Ca2+ channel blocker, NS-7, prevents suppression of cyclic AMP-dependent protein kinase and reduces infarct area in the acute phase of cerebral ischemia in rat

Kortaro Tanaka, Y. Fukuuchi, A. Kosakai, 2002, Brain Research.

Characterization of inclusion bodies with cytoprotective properties formed by seipinopathy-linked mutant seipin.

M. Ikawa, D. Ito, N. Suzuki, 2012, Human molecular genetics.

Ropinirole hydrochloride for amyotrophic lateral sclerosis: A single-center, randomized feasibility, double-blind, placebo-controlled trial

M. Jinzaki, D. Ito, N. Suzuki, 2021, medRxiv.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Activation of NG2-positive oligodendrocyte progenitor cells during post-ischemic reperfusion in the rat brain

Kortaro Tanaka, Y. Fukuuchi, A. Kosakai, 2001, Neuroreport.

D. Ito, N. Suzuki, T. Yagi, 2011, Rinsho shinkeigaku = Clinical neurology.

Slow-progressive ataxia with a methionine-to-arginine point mutation in codon 232 in the prion protein gene (PRNP)

D. Ito, Shigeaki Suzuki, N. Suzuki, 2011, Clinical Neurology and Neurosurgery.

Promise of Nucleic Acid Therapeutics for Amyotrophic Lateral Sclerosis

D. Ito, 2021, Annals of neurology.

A561C polymorphism of E-selectin is associated with ischemic cerebrovascular disease in the Japanese population without diabetes mellitus and hypercholesterolemia

H. Hattori, D. Ito, N. Suzuki, 2006, Brain Research.

Progressive multifocal leukoencephalopathy developed in incomplete Heerfordt syndrome, a rare manifestation of sarcoidosis, without steroid therapy responding to cidofovir

H. Hattori, M. Saijo, D. Ito, 2010, Clinical Neurology and Neurosurgery.

Activation of NG2-Positive Oligodendrocyte Progenitor Cells after Focal Ischemia in Rat Brain

A. Kosakai, S. Nogawa, D. Ito, 2004 .

Activation and proliferation of oligodendrocyte progenitor cells after brain ischemia in the rat

Kortaro Tanaka, A. Kosakai, S. Nogawa, 2003 .

Evaluation of [18F]PI-2620, a second-generation selective tau tracer, for assessing four-repeat tauopathies

M. Jinzaki, M. Mimura, R. Ueda, 2021, Brain communications.

A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer

Takashi Sasaki, T. Kondo, D. Ito, 2022, Cell reports methods.

Establishment of KEIOi005-A iPSC line from urine-derived cells (UDCs) of a mild Alzheimer's disease (AD) donor with multiple risk SNPs for sporadic Alzheimer's disease (sAD).

S. Maeda, H. Okano, M. Mimura, 2022, Stem cell research.

T280M and V249I polymorphisms of fractalkine receptor CX3CR1 and ischemic cerebrovascular disease

H. Hattori, D. Ito, N. Suzuki, 2005, Neuroscience Letters.

Impact of Amyloid and Tau PET on Changes in Diagnosis and Patient Management

M. Jinzaki, M. Mimura, R. Ueda, 2022, Neurology.

Diagnostic accuracy of neuropsychological tests for classification of dementia

M. Mimura, D. Ito, N. Suzuki, 2016 .

Modeling familial Alzheimer's disease with induced pluripotent stem cells.

H. Okano, S. Yamanaka, D. Ito, 2011, Human molecular genetics.

Alpha‐synuclein dynamics in induced pluripotent stem cell‐derived dopaminergic neurons from a Parkinson’s disease patient (PARK4) with SNCA triplication

H. Okano, T. Shofuda, Y. Kanemura, 2020, FEBS open bio.

Establishment of Induced Pluripotent Stem Cells from Centenarians for Neurodegenerative Disease Research

H. Okano, F. Ishikawa, A. Nabetani, 2012, PloS one.

Enhanced Aggregation of Androgen Receptor in Induced Pluripotent Stem Cell-derived Neurons from Spinal and Bulbar Muscular Atrophy*

H. Okano, D. Ito, N. Suzuki, 2013, The Journal of Biological Chemistry.

Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue

H. Okano, Tetsuro Kobayashi, N. Hattori, 2012, Molecular Brain.

Accelerating progress in induced pluripotent stem cell research for neurological diseases

H. Okano, D. Ito, N. Suzuki, 2012, Annals of neurology.

[Advances in induced pluripotent stem cell research for neurological diseases].

D. Ito, N. Suzuki, T. Yagi, 2010, Rinsho shinkeigaku = Clinical neurology.

Dendritic Homeostasis Disruption in a Novel Frontotemporal Dementia Mouse Model Expressing Cytoplasmic Fused in Sarcoma

S. Itohara, M. Yuzaki, D. Ito, 2017, EBioMedicine.

Mislocated FUS is sufficient for gain-of-toxic-function amyotrophic lateral sclerosis phenotypes in mice.

Norihiro Suzuki, D. Ito, N. Suzuki, 2016, Brain : a journal of neurology.

FUS is Phosphorylated by DNA-PK and Accumulates in the Cytoplasm after DNA Damage

N. Seyfried, M. Murray, D. Dickson, 2014, The Journal of Neuroscience.

Conjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUS

D. Ito, N. Suzuki, 2011, Neurology.

Notch3 gene polymorphism and ischaemic cerebrovascular disease

Y. Fukuuchi, D. Ito, M. Murata, 2002, Journal of neurology, neurosurgery, and psychiatry.

Temporal Profile and Cellular Localization of Interleukin-6 Protein after Focal Cerebral Ischemia in Rats

E. Nagata, Kortaro Tanaka, Y. Fukuuchi, 1999, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Cerebral neurons express interleukin-6 after transient forebrain ischemia in gerbils

E. Nagata, Kortaro Tanaka, Y. Fukuuchi, 1999, Neuroscience Letters.

Multiple sclerosis associated with interferon‐alpha therapy for chronic myelogenous leukemia

M. Harada, D. Ito, R. Watanabe, 2002, American journal of hematology.

Immunohistochemical Detection of Leukemia Inhibitory Factor After Focal Cerebral Ischemia in Rats

Kortaro Tanaka, Y. Fukuuchi, A. Kosakai, 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Swift transformation and locomotion of polymorphonuclear leukocytes and microglia as observed by VEC-DIC microscopy (video microscopy).

S. Terakawa, Y. Fukuuchi, D. Ito, 1996, The Keio journal of medicine.

Enhanced Expression of Iba1, Ionized Calcium-Binding Adapter Molecule 1, After Transient Focal Cerebral Ischemia In Rat Brain

Kortaro Tanaka, Y. Fukuuchi, D. Ito, 2001, Stroke.

Meningoencephalopathy as a clinical manifestation of Epstein–Barr virus‐associated hemophagocytic syndrome

D. Ito, N. Suzuki, S. Momoshima, 2013 .

Characterization of the dipeptide repeat protein in the molecular pathogenesis of c9FTD/ALS.

D. Ito, N. Suzuki, K. Nakajima, 2015, Human molecular genetics.

Genotype Distribution of the 46C/T Polymorphism of Coagulation Factor XII in the Japanese Population: Absence of Its Association with Ischemic Cerebrovascular Disease

Y. Fukuuchi, D. Ito, M. Murata, 2000, Thrombosis and Haemostasis.

Molecular Cloning and Characterization of Annexin V‐Binding Proteins with Highly Hydrophilic Peptide Structure

Y. Imai, D. Ito, S. Kohsaka, 1996, Journal of neurochemistry.

Paroxysmal hypertensive crises induced by selegiline in a patient with Parkinson's disease

Y. Fukuuchi, D. Ito, T. Amano, 2001, Journal of Neurology.

Sjögren's syndrome with paresis of the internal branch of the superior laryngeal nerve

S. Nogawa, D. Ito, N. Suzuki, 2014 .

Comprehensive and long-term surveys of COVID-19 sequelae in Japan, an ambidirectional multicentre cohort study: study protocol

M. Mimura, K. Tsubota, Yusuke Suzuki, 2021, BMJ Open Respiratory Research.

The psychological impact of disclosing amyloid status to Japanese elderly: a preliminary study on asymptomatic patients with subjective cognitive decline

M. Jinzaki, M. Mimura, M. Kameyama, 2017, International Psychogeriatrics.

Effect of different parietal hypoperfusion on neuropsychological characteristics in mild cognitive impairment

M. Mimura, B. Yamagata, D. Ito, 2021, Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society.

[The cutting-edge of medicine: progress and prospects: induced pluripotent stem cell research for neurological diseases].

D. Ito, N. Suzuki, 2013, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine.

The utility of simple questions to evaluate cognitive impairment

M. Mimura, D. Ito, Yoko Eguchi, 2020, PloS one.

Persistent CREB Phosphorylation with Protection of Hippocampal CA1 Pyramidal Neurons Following Temporary Occlusion of the Middle Cerebral Artery in the Rat

E. Nagata, Kortaro Tanaka, Y. Fukuuchi, 2000, Experimental Neurology.

Chronic ethanol consumption enhances endotoxin induced hepatic sinusoidal leukocyte adhesion.

H. Ishii, D. Ito, I. Kurose, 1996, Alcoholism, clinical and experimental research.

Extensive splicing changes in an ALS/FTD transgenic mouse model overexpressing cytoplasmic fused in sarcoma

D. Ito, Ryota Taguchi, E. Inoue, 2020, Scientific Reports.

Evidence of a link between ubiquilin 2 and optineurin in amyotrophic lateral sclerosis.

D. Ito, N. Suzuki, T. Yagi, 2015, Human molecular genetics.

Characterization of Alternative Isoforms and Inclusion Body of the TAR DNA-binding Protein-43*

D. Ito, N. Suzuki, T. Yagi, 2009, The Journal of Biological Chemistry.

A diagnostic strategy for Parkinsonian syndromes using quantitative indices of DAT SPECT and MIBG scintigraphy: an investigation using the classification and regression tree analysis

M. Jinzaki, M. Kameyama, D. Ito, 2021, European Journal of Nuclear Medicine and Molecular Imaging.

Disturbance of proteasomal and autophagic protein degradation pathways by amyotrophic lateral sclerosis-linked mutations in ubiquilin 2.

D. Ito, N. Suzuki, Mayuko Osaka, 2016, Biochemical and biophysical research communications.

Disclosure of Amyloid Status for Risk of Alzheimer Disease to Cognitively Normal Research Participants With Subjective Cognitive Decline: A Longitudinal Study

M. Jinzaki, M. Mimura, B. Yamagata, 2020, American journal of Alzheimer's disease and other dementias.

Seipinopathy: a novel endoplasmic reticulum stress-associated disease.

D. Ito, N. Suzuki, 2009, Brain : a journal of neurology.

Corneal endothelial degeneration in dentatorubral-pallidoluysian atrophy.

Y. Fukuuchi, D. Ito, M. Kawai, 2002, Archives of neurology.

Differential toxicity and localization of arginine-rich C9ORF72 dipeptide repeat proteins depend on de-clustering of positive charges

Koji Ueda, M. Sugimoto, H. Uji‐i, 2023, iScience.

A novel compound heterozygous dysferlin mutation in Miyoshi myopathy siblings responding to dantrolene

H. Hattori, D. Ito, N. Suzuki, 2007, European journal of neurology.

Retinopathy: an overlooked adverse effect of interferon-beta treatment of multiple sclerosis.

M. Shibata, D. Ito, N. Suzuki, 2009, The Keio journal of medicine.

Phase 1/2a clinical trial in ALS with ropinirole, a drug candidate identified by iPSC drug discovery.

H. Okano, M. Jinzaki, D. Ito, 2023, Cell stem cell.

G501C polymorphism of oxidized LDL receptor gene (OLR1) and ischemic stroke

H. Hattori, D. Ito, N. Suzuki, 2006, Brain Research.

Neuroanatomical Characterisation of the Expression of the Lipodystrophy and Motor-Neuropathy Gene Bscl2 in Adult Mouse Brain

A. Garfield, D. Ito, L. Heisler, 2012, PloS one.

Hydrogen peroxide enhances phagocytic activity of ameboid microglia

Y. Fukuuchi, D. Ito, M. Tomita, 1998, Neuroscience Letters.

A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage.

Y. Imai, D. Ito, S. Kohsaka, 1996, Biochemical and biophysical research communications.

Quantitative evaluation of the tracer distribution in dopamine transporter SPECT for objective interpretation

M. Jinzaki, M. Kameyama, D. Ito, 2018, Annals of Nuclear Medicine.

Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue

H. Okano, Tetsuro Kobayashi, N. Hattori, 2012, Molecular Brain.

[Genetic risk factors for ischemic cerebrovascular disease--analysis on fifteen candidate prothrombotic gene polymorphisms in the Japanese population].

Y. Fukuuchi, D. Ito, M. Murata, 2004, Rinsho byori. The Japanese journal of clinical pathology.

Uncoupling of cerebral blood flow and glucose utilization in the regenerating facial nucleus after axotomy

E. Nagata, Kortaro Tanaka, Y. Fukuuchi, 1999, Neuroscience Research.