N. Ikegaki

J. Maris, H. Shimada, S. Asgharzadeh, 2018, Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.

Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression

A. Eggert, N. Ikegaki, G. Brodeur, 2000, Oncogene.

Combined application of Indocyanine green (ICG) and laser lead to targeted tumor cell destruction.

B. Chiu, N. Ikegaki, Liaohai Chen, 2018, Journal of pediatric surgery.

High levels of N-myc protein in a neuroblastoma cell line lacking N-myc amplification.

R. Kennett, N. Ikegaki, S. Cohn, 1991, Progress in clinical and biological research.

Down-regulation of MYCN protein by CX-5461 leads to neuroblastoma tumor growth suppression.

H. Shimada, B. Chiu, N. Ikegaki, 2019, Journal of pediatric surgery.

Prognostic significance of EPHB6, EFNB2, and EFNB3 expressions in neuroblastoma.

M. E. Robinson, A. Cnaan, N. Cheung, 2000, Medical and pediatric oncology.

Glutaraldehyde fixation of the primary antibody-antigen complex on nitrocellulose paper increases the overall sensitivity of immunoblot assay.

R. Kennett, N. Ikegaki, Roger H. Kennett, 1989, Journal of immunological methods.

In vitro and in vivo evaluation of etoposide ‐ silk wafers for neuroblastoma treatment

D. Kaplan, B. Chiu, N. Ikegaki, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Coexpression of transcripts encoding EPHB receptor protein tyrosine kinases and their ephrin-B ligands in human small cell lung carcinoma.

N. Ikegaki, G. Brodeur, B. Campling, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Expression of N‐methyl‐D‐aspartate (NMDA) and non‐NMDA glutamate receptor genes in neuroblastoma, medulloblastoma, and other cell lines

D. Pleasure, N. Ikegaki, A. Yoshioka, 1996, Journal of neuroscience research.

cDNA cloning, molecular characterization, and chromosomal localization of NET(EPHT2), a human EPH-related receptor protein-tyrosine kinase gene preferentially expressed in brain.

J. Biegel, D. Pleasure, N. Ikegaki, 1995, Genomics.

TrkA signal transduction pathways in neuroblastoma.

A. Eggert, N. Ikegaki, G. Brodeur, 2001, Medical and pediatric oncology.

Design, Synthesis, and Biological Evaluation of Tetrahydroisoquinoline-Based Histone Deacetylase 8 Selective Inhibitors.

G. Thatcher, N. Ikegaki, P. Petukhov, 2017, ACS medicinal chemistry letters.

Clinical Relevance of CD4 Cytotoxic T Cells in High-Risk Neuroblastoma

H. Shimada, N. Ikegaki, Xao X. Tang, 2021, Frontiers in Immunology.

Implantable chemotherapy‐loaded silk protein materials for neuroblastoma treatment

D. Kaplan, D. Kaplan, H. Shimada, 2017, International journal of cancer.

3,4-Dihydroxyphenylalanine (DOPA) metabolism and retinoic acid induced differentiation in human neuroblastoma

David F Wilson, R. Kennett, A. Pastuszko, 1994, Neurochemical Research.

Molecular genetic characterization of epitope-specific monoclonal antibodies against the myc family proteins.

R. Kennett, N. Ikegaki, 1990, Oncogene.

Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression.

R. Ho, A. Eggert, N. Ikegaki, 2001, Cancer research.

Cloning and chromosomal localization of the human TRK-B tyrosine kinase receptor gene (NTRK2).

J. Biegel, A. Nakagawara, P. White, 1995, Genomics.

An alternative view of T-cell receptor-MHC interaction: T-cell receptor binds transversally to the alpha-helices of the MHC molecule.

J. Danska, N. Ikegaki, E. Heber-Katz, 1995, Molecular immunology.

Expression of neurotrophin receptor TrkA inhibits angiogenesis in neuroblastoma.

A. Eggert, N. Ikegaki, A. Evans, 2000, Medical and pediatric oncology.

Destabilization of MYC/MYCN by the mitochondrial inhibitors, metaiodobenzylguanidine, metformin and phenformin

N. Ikegaki, Sarah Lomahan, T. Tran, 2013, International journal of molecular medicine.

The MYCN enigma: significance of MYCN expression in neuroblastoma.

N. Cheung, R. Seeger, N. Ikegaki, 2006, Cancer research.

Neuroblastoma and Neuroblastic Tumors

H. Shimada, N. Ikegaki, 2018 .

Augmented expression of MYC and/or MYCN protein defines highly aggressive MYC-driven neuroblastoma: a Children's Oncology Group study

A. Look, A. Naranjo, J. Gastier-Foster, 2015, British Journal of Cancer.

Expression of TrkC in favorable human neuroblastomas.

A. Nakagawara, N. Ikegaki, G. Brodeur, 1996, Oncogene.

Genetic and Histopathological Heterogeneity of Neuroblastoma and Precision Therapeutic Approaches for Extremely Unfavorable Histology Subgroups

H. Shimada, N. Ikegaki, 2022, Biomolecules.

Neuroblastoma Pathology

N. Ikegaki, B. Pawel, A. Sementa, 2019, Neuroblastoma.

Subgrouping of Unfavorable Histology Neuroblastomas With Immunohistochemistry Toward Precision Prognosis and Therapy Stratification.

H. Shimada, N. Ikegaki, 2019, JCO precision oncology.

Neuroblastoma Pathology and Classification for Precision Prognosis and Therapy Stratification

H. Shimada, N. Ikegaki, 2019, Neuroblastoma.

Combined Replenishment of miR-34a and let-7b by Targeted Nanoparticles Inhibits Tumor Growth in Neuroblastoma Preclinical Models.

D. Ferrari, D. Brown, D. Ribatti, 2020, Small.

Enhancing sustained-release local therapy: Single versus dual chemotherapy for the treatment of neuroblastoma.

D. Kaplan, L. Wood, H. Shimada, 2020, Surgery.

Neuroblastoma of undifferentiated subtype, prognostic significance of prominent nucleolar formation, and MYC/MYCN protein expression: A report from the Children's Oncology Group

A. Look, A. Naranjo, J. Gastier-Foster, 2013, Cancer.

The biological effects of antisense N-myc expression in human neuroblastoma.

C. Manohar, N. Ikegaki, S. Cohn, 1994, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

ZPK inhibits PKA induced transcriptional activation by CREB and blocks retinoic acid induced neuronal differentiation

D. Pleasure, N. Ikegaki, C. Reddy, 1999, Oncogene.

Molecular dissection of TrkA signal transduction pathways mediating differentiation in human neuroblastoma cells

J. Trojanowski, V. Lee, A. Eggert, 2000, Oncogene.

Biological significance of EPHA 2 expression in neuroblastoma

N. Ikegaki, Huaqing Zhao, B. Kung, 2022 .

The effects of gamma interferon on the natural killer and tumor cells of children with neuroblastoma. A preliminary report

R. Kennett, N. Ikegaki, L. Lampson, 1989, Cancer.

Relationship between bcl-2 and myc gene expression in human neuroblastoma.

A. Nakagawara, N. Ikegaki, G. Brodeur, 1995, Cancer letters.

MYCN protein expression as a predictor of neuroblastoma prognosis.

B. Gallie, V. Ling, H. Yeger, 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

High-level expression of angiogenic factors is associated with advanced tumor stage in human neuroblastomas.

A. Eggert, N. Ikegaki, G. Brodeur, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Unified Nomenclature for Eph Family Receptors and Their Ligands, the Ephrins

T Pawson, C. Goodman, T. Pawson, 1997, Cell.

p75 mediated apoptosis in neuroblastoma cells is inhibited by expression of TrkA.

A. Eggert, N. Ikegaki, G. Brodeur, 2000, Medical and pediatric oncology.

De novo Identification of MIZ-1 (ZBTB17) Encoding a MYC-Interacting Zinc-Finger Protein as a New Favorable Neuroblastoma Gene

E. Rappaport, R. Seeger, N. Ikegaki, 2007, Clinical Cancer Research.

Implications of EPHB6, EFNB2, and EFNB3 expressions in human neuroblastoma.

M. E. Robinson, B. M. Cohen, A. Cnaan, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Expression of the neurotrophin receptor TrkA down-regulates expression and function of angiogenic stimulators in SH-SY5Y neuroblastoma cells.

A. Eggert, N. Ikegaki, A. Evans, 2002, Cancer research.

MYC-family protein overexpression and prominent nucleolar formation represent prognostic indicators and potential therapeutic targets for aggressive high-MKI neuroblastomas: a report from the children’s oncology group

A. Look, A. Naranjo, J. Gastier-Foster, 2017, Oncotarget.

Disseminated injection of vincristine‐loaded silk gel improves the suppression of neuroblastoma tumor growth

D. Kaplan, B. Chiu, N. Ikegaki, 2018, Surgery.

Stage 4 S Neuroblastoma Molecular , Histologic , and Immunohistochemical Characteristics and Presence of 2 Distinct Patterns of MYCN Protein Overexpression — A Report From the Children ’ s Oncology Group

F. Hazard, A. Naranjo, J. Gastier-Foster, 2021 .

Stage 4S Neuroblastoma

F. Hazard, A. Naranjo, J. Gastier-Foster, 2020, The American journal of surgical pathology.

Inhibition of N-myc expression and induction of apoptosis by iron chelation in human neuroblastoma cells.

R. Kennett, N. Ikegaki, Randal K. Wada, 2001, Cancer research.

Iron Chelation in Human Neuroblastoma Cells Expression and Induction of Apoptosis by-myc Inhibition of N Updated

R. Kennett, N. Ikegaki, C. Frantz, 2001 .

Prolonged N-myc protein half-life in a neuroblastoma cell line lacking N-myc amplification.

Joseph A. DiGiuseppe, R. Kennett, N. Ikegaki, 1990, Oncogene.

Identification and characterization of the NMYC gene product in human neuroblastoma cells by monoclonal antibodies with defined specificities.

R. Kennett, N. Ikegaki, R. H. Kennett, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Purification and characterization of hemoglobin-hydrolyzing acidic thiol protease induced by leupeptin in rat liver.

K. Tanaka, N. Ikegaki, A. Ichihara, 1984, The Journal of biological chemistry.

High-level expression of EPHB6, EFNB2, and EFNB3 is associated with low tumor stage and high TrkA expression in human neuroblastomas.

A. Cnaan, W. London, N. Ikegaki, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

A variant transcript encoding an isoform of the human protein tyrosine kinase EPHB2 is generated by alternative splicing and alternative use of polyadenylation signals

D. Pleasure, N. Ikegaki, G. Brodeur, 1998, Oncogene.

Identification of epitope recognized by an anti-c-myc monoclonal antibody that cross-reacts with E. coli sigma factor using phage display libraries.

B. Kay, R. Kennett, N. Ikegaki, 1996, Immunotechnology : an international journal of immunological engineering.

Modulation of N-myc expression alters the invasiveness of neuroblastoma

C. Thiele, N. Ikegaki, S. Cohn, 1997, Clinical & Experimental Metastasis.

Association among EPHB2, TrkA, and MYCN expression in low-stage neuroblastomas.

A. Cnaan, N. Ikegaki, A. Evans, 2001, Medical and pediatric oncology.

High-Level Expression of EPHB 6 , EFNB 2 , and EFNB 3 Is Associated with Low Tumor Stage and High TrkA Expression in Human Neuroblastomas 1

A. Cnaan, W. London, N. Ikegaki, 1999 .

Age Inherently Links to Histology to Define Histoprognostic Classification of Peripheral Neuroblastic Tumors.

H. Shimada, K. Beiske, N. Ikegaki, 2020, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Replicating and identifying large cell neuroblastoma using high-dose intra-tumoral chemotherapy and automated digital analysis.

D. Kaplan, Lingdao Sha, H. Shimada, 2019, Journal of pediatric surgery.

The expression and modulation of proteins associated with physiological cell death in neuroblastoma cells.

N. Ikegaki, M. Kastumata, Y. Tsujimoto, 1994, Progress in clinical and biological research.

Expression o f t he N eurotrophin R eceptor T rkB I s Associated W ith U nfavorable O utcome i n W ilms' T umor

A. Cnaan, A. Eggert, N. Ikegaki, 2001 .

Expression and function of Trk-C in favourable human neuroblastomas.

S. Baylin, A. Nakagawara, N. Ikegaki, 1997, European journal of cancer.

Neuroblastoma of undifferentiated subtype, prognostic significance of prominent nucleolar formation, and MYC/MYCN protein expression: A report from the Children's Oncology Group

A. Look, A. Naranjo, J. Gastier-Foster, 2013, Cancer.

in a Neuroepithelioma Cell Line Protein myc in Decreased Cell Growth without Reduction of c-Expression Results myc Antisense Inhibition of Single Copy N-Updated

L. Neckers, R. Kennett, N. Ikegaki, 2006 .

Effect of 20-epi-1alpha,25-dihydroxyvitamin D3 on the proliferation of human neuroblastoma: role of cell cycle regulators and the Myc-Id2 pathway.

N. Ikegaki, Kiranmai Gumireddy, Leslie N. Sutton, 2003, Biochemical pharmacology.

Antisense inhibition of N-myc reduces cell growth but does not affect c-myc expression in the neuroepithelioma cell line CHP100.

L. Neckers, R. Kennett, N. Ikegaki, 1991, Progress in clinical and biological research.

A Perspective on the CD47-SIRPA Axis in High-Risk Neuroblastoma

N. Ikegaki, Xao X. Tang, Hiroyuki Shimada, 2024, Current oncology.

Induction of hemoglobin-hydrolase activity by the thiol-protease inhibitors leupeptin and antipain in adult rat liver cells in primary culture.

N. Ikegaki, K. Tanaka, A. Ichihara, 1979, Biochemical and biophysical research communications.