B. Evert

发表

Bcl-2 up-regulates ha-ras mRNA expression and induces c-Jun phosphorylation at Ser73 via an ERK-dependent pathway in PC 12 cells

T. Klockgether, C. Schwarz, J. Seyfried, 2002, Neuroreport.

CK2-dependent phosphorylation determines cellular localization and stability of ataxin-3.

B. Evert, U. Wüllner, J. Walter, 2009, Human molecular genetics.

Rapamycin alleviates toxicity of different aggregate-prone proteins.

D. Rubinsztein, B. Ravikumar, F. Menzies, 2006, Human molecular genetics.

Upregulation of miR-370 and miR-543 is associated with reduced expression of heat shock protein 40 in spinocerebellar ataxia type 3

S. Bonn, B. Evert, O. Brüstle, 2018, PloS one.

Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma.

T. Klockgether, N. Bogdanovic, E. Rosen, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Structural modeling of ataxin‐3 reveals distant homology to adaptins

Thomas Lengauer, M. Albrecht, B. Evert, 2002, Proteins.

Nuclear Aggregation of Polyglutamine-expanded Ataxin-3

B. Evert, U. Wüllner, P. Breuer, 2010, The Journal of Biological Chemistry.

Contributes to Development of CD4+ T Cell Control of Dendritic Cell Function γ Peroxisome Proliferator-Activated Receptor

B. Evert, I. Dani, P. Knolle, 2013 .

Peroxisome Proliferator-Activated Receptor γ Control of Dendritic Cell Function Contributes to Development of CD4+ T Cell Anergy

T. Klockgether, B. Evert, I. Dani, 2007, The Journal of Immunology.

Pathological consequences of VCP mutations on human striated muscle.

E. Wanker, A. Noegel, V. Kimonis, 2007, Brain : a journal of neurology.

Mutant valosin‐containing protein causes a novel type of frontotemporal dementia

K. Fliessbach, S. Mehta, V. Hans, 2005, Annals of neurology.

Neuronal intranuclear inclusions, dysregulation of cytokine expression and cell death in spinocerebellar ataxia type 3.

T. Klockgether, W. Stenzel, B. Evert, 2006, Clinical neuropathology.

Inhibition of Gap Junctions Sensitizes Primary Glioblastoma Cells for Temozolomide

H. Vatter, B. Evert, T. Pietsch, 2019, Cancers.

FOXO 4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3

T. Klockgether, B. Evert, A. Pfeifer, 2011 .

FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3.

T. Klockgether, B. Evert, A. Pfeifer, 2011, Human molecular genetics.

An arginine/lysine‐rich motif is crucial for VCP/p97‐mediated modulation of ataxin‐3 fibrillogenesis

S. Plassmann, E. Wanker, J. Suopanki, 2006, The EMBO journal.

Flupirtine and retigabine prevent L-glutamate toxicity in rat pheochromocytoma PC 12 cells.

J. Schulz, T. Klockgether, J. Seyfried, 2000, European journal of pharmacology.

Inflammatory Genes Are Upregulated in Expanded Ataxin-3-Expressing Cell Lines and Spinocerebellar Ataxia Type 3 Brains

T. Klockgether, B. Evert, U. Wüllner, 2001, The Journal of Neuroscience.

Inactivation of the mouse Atxn3 (ataxin-3) gene increases protein ubiquitination.

T. Klockgether, B. Evert, I. Schmitt, 2007, Biochemical and biophysical research communications.

Binding of copper is a mechanism of homocysteine toxicity leading to COX deficiency and apoptosis in primary neurons, PC12 and SHSY-5Y cells

T. Klockgether, B. Evert, U. Wüllner, 2006, Neurobiology of Disease.

Mutant huntingtin represses CBP, but not p300, by binding and protein degradation.

R. Roos, D. Rubinsztein, G. van Ommen, 2005, Molecular and cellular neurosciences.

Inhibition of Intercellular Cytosolic Traffic via Gap Junctions Reinforces Lomustine-Induced Toxicity in Glioblastoma Independent of MGMT Promoter Methylation Status

H. Vatter, B. Evert, T. Pietsch, 2021, Pharmaceuticals.

INFLUENCE OF PHARMACOGENETICS ON DRUG DISPOSITION AND RESPONSE

M. Eichelbaum, B. Evert, 1996, Clinical and experimental pharmacology & physiology.

Activators of alpha synuclein expression identified by reporter cell line-based high throughput drug screen

B. Evert, U. Wüllner, P. Breuer, 2021, Scientific Reports.

Potassium channel dysfunction and depolarized resting membrane potential in a cell model of SCA3

A. Spauschus, M. Herbst, T. Klockgether, 2006, Experimental Neurology.

Comprehensive analysis of the genetic factors determining expression and function of hepatic CYP2D6.

M Schwab, M. Eichelbaum, B. Evert, 2001, Pharmacogenetics.

The Role of MicroRNAs in Spinocerebellar Ataxia Type 3.

B. Evert, S. Krauß, 2019, Journal of molecular biology.

Upregulation of miR-25 and miR-181 Family Members Correlates with Reduced Expression of ATXN3 in Lymphocytes from SCA3 Patients.

B. Evert, R. Nalavade, S. Weber, 2018, MicroRNA.

Reciprocal Regulation between Bifunctional miR-9/9∗ and its Transcriptional Modulator Notch in Human Neural Stem Cell Self-Renewal and Differentiation

B. Evert, O. Brüstle, B. Roese-Koerner, 2016, Stem cell reports.

Excitation-induced ataxin-3 aggregation in neurons from patients with Machado–Joseph disease

J. Mertens, T. Klockgether, P. Hoffmann, 2011, Nature.

Gene dosage-dependent effects of bcl-2 expression on cellular survival and redox status.

J. Schulz, T. Klockgether, C. Schwarz, 2003, Free radical biology & medicine.

Overexpression of bcl-2 results in reduction of cytochrome c content and inhibition of complex I activity.

T. Klockgether, C. Schwarz, J. Seyfried, 2001, Biochemical and biophysical research communications.

Different methylation of the TNF-alpha promoter in cortex and substantia nigra: Implications for selective neuronal vulnerability

P. Riederer, B. Evert, U. Wüllner, 2008, Neurobiology of Disease.

Transcriptional changes in multiple system atrophy and Parkinson's disease putamen

T. Klockgether, A. Lees, M. Bonin, 2006, Experimental Neurology.

Ataxin-3 Represses Transcription via Chromatin Binding, Interaction with Histone Deacetylase 3, and Histone Deacetylation

T. Klockgether, B. Evert, U. Wüllner, 2006, The Journal of Neuroscience.

Mutant huntingtin represses CBP, but not p300, by binding and protein degradation

Josephine C. Dorsman, R. Roos, D. Rubinsztein, 2005, Molecular and Cellular Neuroscience.

The molecular biology of the autosomal‐dominant cerebellar ataxias

A. Spauschus, T. Klockgether, B. Evert, 2000, Movement disorders : official journal of the Movement Disorder Society.

Genes involved in hereditary ataxias

T. Klockgether, B. Evert, 1998, Trends in Neurosciences.

Cell death in polyglutamine diseases

T. Klockgether, B. Evert, U. Wüllner, 2000, Cell and Tissue Research.

Neuropathic pain in experimental autoimmune neuritis is associated with altered electrophysiological properties of nociceptive DRG neurons

H. Beck, A. Becker, B. Evert, 2017, Experimental Neurology.

Mechanisms of cell death in cerebellar disorders.

T. Klockgether, B. Evert, U. Wüllner, 1998, Restorative neurology and neuroscience.

Meclofenamate causes loss of cellular tethering and decoupling of functional networks in glioblastoma.

U. Hofmann, M. Meyer-Luehmann, J. Beck, 2021, Neuro-oncology.

High level expression of expanded full-length ataxin-3 in vitro causes cell death and formation of intranuclear inclusions in neuronal cells.

J. Schulz, M. Weller, T. Klockgether, 1999, Human molecular genetics.

Functional properties of CYP2D6 1 (wild-type) and CYP2D6 7 (His324Pro) expressed by recombinant baculovirus in insect cells

M. Eichelbaum, B. Evert, U. Zanger, 1997, Naunyn-Schmiedeberg's Archives of Pharmacology.

Cloning and sequencing of a new non-functional CYP2D6 allele: deletion of T1795 in exon 3 generates a premature stop codon.

M. Eichelbaum, B. Evert, E. Griese, 1994, Pharmacogenetics.

Is the molecular clock ticking differently in bipolar disorder? Methylation analysis of the clock gene ARNTL

H. Kapfhammer, B. Evert, R. Fuchs, 2018, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

Gene Expression Profiling in Ataxin‐3 Expressing Cell Lines Reveals Distinct Effects of Normal and Mutant Ataxin‐3

T. Klockgether, B. Evert, U. Wüllner, 2003, Journal of neuropathology and experimental neurology.

ATXN3 controls DNA replication and transcription by regulating chromatin structure

N. Mailand, Kristijan Ramadan, V. Smits, 2023, Nucleic acids research.

The human MJD gene: genomic structure and functional characterization of the promoter region.

T. Klockgether, B. Evert, I. Schmitt, 2003, Gene.

Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma.

Michael T Heneka, Thomas Klockgether, T. Klockgether, 2006, Proceedings of the National Academy of Sciences of the United States of America.

A missense mutation in exon 6 of the CYP2D6 gene leading to a histidine 324 to proline exchange is associated with the poor metabolizer phenotype of sparteine

M. Eichelbaum, B. Evert, E. Griese, 1994, Naunyn-Schmiedeberg's Archives of Pharmacology.

A missense mutation in exon 6 of the CYP2D6 gene to a histidine 324 to proline exchange is associated with the poor metabolizer phenotype of sparteine leading

B. Evert, E. Griese, Michel Eicheibaum, 1994 .

Downregulation of MGMT expression by targeted editing of DNA methylation enhances temozolomide sensitivity in glioblastoma

B. Evert, U. Wüllner, P. Breuer, 2023, Neoplasia.

Nonsteroidal anti-inflammatory drugs repress (cid:1) -secretase gene promoter activity by the activation of PPAR (cid:2)

T. Klockgether, N. Bogdanovic, E. Rosen, 2005 .

FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3.

T. Klockgether, B. Evert, A. Pfeifer, 2011, Human molecular genetics.

Neuropathic pain in experimental autoimmune neuritis is associated with altered electrophysiological properties of nociceptive DRG neurons

H. Beck, A. Becker, B. Evert, 2017, Experimental Neurology.

Spinocerebellar Ataxia Type 3 Pathophysiology—Implications for Translational Research and Clinical Studies

B. Evert, P. Breuer, Ullrich Wüllner, 2024, International journal of molecular sciences.

The Alpha-Synuclein Gene (SNCA) is a Genomic Target of Methyl-CpG Binding Protein 2 (MeCP2)—Implications for Parkinson’s Disease and Rett Syndrome

Amit Sharma, B. Evert, Hassan Khazneh, 2024, Molecular neurobiology.