M. Sasaki

发表

Interference by Huntingtin and Atrophin-1 with CBP-Mediated Transcription Leading to Cellular Toxicity

C A Ross, C. Ross, S. Tsuji, 2001, Science.

Poly(ADP-ribose) (PAR) polymer is a death signal

R. Koehler, T. Dawson, V. Dawson, 2006, Proceedings of the National Academy of Sciences.

Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality.

S. Wattler, M. Nehls, T. Dawson, 2004, Proceedings of the National Academy of Sciences of the United States of America.

DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase

T. Dawson, V. Dawson, T. Greco, 2007, Proceedings of the National Academy of Sciences.

Immunologic NO Synthase: Elevation in Severe AIDS Dementia and Induction by HIV-1 gp41

Justin C. McArthur, Jonathan D. Glass, Ted M. Dawson, 1996, Science.

AIF3 splicing switch triggers neurodegeneration

T. Dawson, V. Dawson, M. Sasaki, 2021, Molecular neurodegeneration.

Nuclear GAPDH cascade mediates pathological cardiac hypertrophy

Carlos A. Tristan, D. Kass, A. Sawa, 2019, bioRxiv.

The mitochondrial regulator PGC1α is induced by cGMP–PKG signaling and mediates the protective effects of phosphodiesterase 5 inhibition in heart failure

D. Kass, R. Karas, B. O’Rourke, 2021, FEBS letters.

Constitutive Inhibition of Transient Receptor Potential Canonical Type 6 (TRPC6) by O-GlcNAcylation at Threonine-221

D. Kass, M. Sasaki, N. Zachara, 2022, bioRxiv.

Blocking Nitric Oxide Toxicity

T. Dawson, V. Dawson, M. Sasaki, 2002 .

The involvement of nitric oxide in the enhanced expression of μ‐opioid receptors during intestinal inflammation in mice

T. Dawson, V. Dawson, M. Sasaki, 2005, British journal of pharmacology.

Damage-induced neuronal endopeptidase (DINE) is a unique metallopeptidase expressed in response to neuronal damage and activates superoxide scavengers.

S. Kiryu-Seo, H. Kiyama, S. Nakagomi, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Dynamic regulation of neuronal NO synthase transcription by calcium influx through a CREB family transcription factor-dependent mechanism.

D. Ginty, T. Dawson, V. Dawson, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Neuronal (type I) nitric oxide synthase regulates nuclear factor kappaB activity and immunologic (type II) nitric oxide synthase expression.

T. Dawson, V. Dawson, E. Frohman, 1997, Proceedings of the National Academy of Sciences of the United States of America.

PKG-Modified TSC2 Regulates mTORC1 Activity to Counter Adverse Cardiac Stress

Dong Ik Lee, David A. Kass, Jennifer E. Van Eyk, 2018, Nature.

Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis

M. Gurney, P. Huang, M. Beal, 1999, Neuroscience.

Unexpected Lack of Hypersensitivity in LRRK2 Knock-Out Mice to MPTP (1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine)

M. Beal, X. Li, T. Dawson, 2009, The Journal of Neuroscience.

The NO Signaling Pathway in the Brain Neural Injury, Neurological Disorders, and Aggression

T. Dawson, M. Sasaki, 2012 .

The NO Signaling Pathway in the Brain

T. Dawson, V. Dawson, M. Sasaki, 2000 .

Loss of locus coeruleus neurons and reduced startle in parkin null mice.

K. Lim, T. Dawson, V. Dawson, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of neuronal nitric oxide synthase and identification of novel nitric oxide signaling pathways.

T. Dawson, V. Dawson, M. Sasaki, 1998, Progress in brain research.

Nitric Oxide in Brain Ischemia/Reperfusion Injury

T. Dawson, V. Dawson, M. Sasaki, 2000 .

EndoG is dispensable in embryogenesis and apoptosis

T. Dawson, V. Dawson, M. Sasaki, 2006, Cell Death and Differentiation.

CHIP phosphorylation by protein kinase G enhances protein quality control and attenuates cardiac ischemic injury

Dong I. Lee, D. Kass, V. Agrawal, 2020, Nature Communications.

Functional Identification of Neuroprotective Molecules

T. Dawson, V. Dawson, M. Sasaki, 2010, PloS one.

The orphan nuclear receptor, steroidogenic factor 1, regulates neuronal nitric oxide synthase gene expression in pituitary gonadotropes.

T. Dawson, V. Dawson, M. Sasaki, 2002, Molecular endocrinology.

A disintegrin and metalloprotease with thrombospondin type1 motifs (ADAMTS-1) and IL-1 receptor type 1 mRNAs are simultaneously induced in nerve injured motor neurons.

M. Sasaki, R. Kato, S. Kita, 2001, Brain research. Molecular brain research.

PKG-Modified TSC2 Regulates mTORC1 Activity to Counter Adverse Cardiac Stress

Dong I. Lee, D. Kass, J. V. Van Eyk, 2018, Nature.

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications

James C. Campbell, Dong I. Lee, M. Zaccolo, 2017, BMC Pharmacology and Toxicology.

Transient receptor potential canonical type 6 (TRPC6) O-GlcNAcylation at Threonine-221 plays potent role in channel regulation

D. Kass, M. Sasaki, N. Zachara, 2023, iScience.