A. Gutierrez-Hartmann

发表

Ets transcription factors: nuclear effectors of the Ras-MAP-kinase signaling pathway.

B. Wasylyk, J. Hagman, A. Gutierrez-Hartmann, 1998, Trends in biochemical sciences.

GHF-1/Pit-1 Functions as a Cell-specific Integrator of Ras Signaling by Targeting the Ras Pathway to a Composite Ets-1/GHF-1 Response Element*

Michael C. Ostrowski, M. Ostrowski, A. Gutierrez-Hartmann, 1996, The Journal of Biological Chemistry.

The c-Jun δ-Domain Inhibits Neuroendocrine Promoter Activity in a DNA Sequence- and Pituitary-specific Manner*

A. Gutierrez-Hartmann, K. N. Farrow, N. Manning, 1996, The Journal of Biological Chemistry.

Persistent ERK/MAPK activation promotes lactotrope differentiation and diminishes tumorigenic phenotype.

M. Lucia, A. Gutierrez-Hartmann, Allyson Booth, 2014, Molecular endocrinology.

Ultrasound-mediated delivery of siESE complexed with microbubbles attenuates HER2+/- cell line proliferation and tumor growth in rodent models of breast cancer

A. Gutierrez-Hartmann, M. Borden, K. Song, 2019, Nanotheranostics.

Identification of Structural Domains of ESX Required for Breast Cell Transformation

A. Gutierrez-Hartmann, 2002 .

Epithelial and Mesenchymal Cell Biology Ets Transcription Factors Control Epithelial Maturation and Transit and Crypt-Villus Morphogenesis in the Mammalian Intestine

L. Sussel, A. Gutierrez-Hartmann, P. Jedlicka, 2010 .

Reconstitution of the protein kinase A response of the rat prolactin promoter: differential effects of distinct Pit-1 isoforms and functional interaction with Oct-1.

A. Gutierrez-Hartmann, M. Chiono, S. E. Diamond, 1999, Molecular endocrinology.

Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia

Christopher C. Porter, Michael Doubek, Kenneth Jones, 2015, Nature Genetics.

ETV6 germline mutations cause HDAC3/NCOR2 mislocalization and upregulation of interferon response genes

Kenneth L. Jones, E. Pietras, A. Gutierrez-Hartmann, 2020, JCI insight.

Cyclic adenosine 3',5'-monophosphate activation of the rat prolactin promoter is restricted to the pituitary-specific cell type.

A. Gutierrez-Hartmann, S. M. Jackson, K. Ocran, 1992, Molecular endocrinology.

Stable accumulation of a rat truncated repeat transcript in Xenopus oocytes.

J. Baxter, A. Gutierrez-Hartmann, 1986, Proceedings of the National Academy of Sciences of the United States of America.

ELF3 is a negative regulator of epithelial-mesenchymal transition in ovarian cancer cells

Samuel C. Mok, S. Mok, K. Wong, 2017, Oncotarget.

ESX induces transformation and functional epithelial to mesenchymal transition in MCF-12A mammary epithelial cells

J. Tentler, K. Brodsky, A. Gutierrez-Hartmann, 2004, Oncogene.

Mapping of ESE-1 subdomains required to initiate mammary epithelial cell transformation via a cytoplasmic mechanism

J. Tentler, A. Gutierrez-Hartmann, Jason D. Prescott, 2011, Molecular Cancer.

High Efficiency Molecular Delivery with Sequential Low-Energy Sonoporation Bursts

M. L. Calvisi, A. Gutierrez-Hartmann, M. Borden, 2015, Theranostics.

Identification of the functional components of the Ras signaling pathway regulating pituitary cell-specific gene expression

A. Gutierrez-Hartmann, G. Johnson, K. Conrad, 1994, Molecular and cellular biology.

Lipoprotein lipase gene expression in rat adipocytes is regulated by isoproterenol and insulin through different mechanisms.

R. Eckel, M. Raynolds, A. Gutierrez-Hartmann, 1990, Molecular endocrinology.

Helix-loop-helix proteins are present and differentially expressed in different cell lines from the anterior pituitary

K. Barnhart, A. Gutierrez-Hartmann, J. Hoeffler, 1993, Molecular and Cellular Endocrinology.

Interaction of Ets-1 and the POU-homeodomain protein GHF-1/Pit-1 reconstitutes pituitary-specific gene expression

B. Wasylyk, A. Gutierrez-Hartmann, A. Bradford, 1997, Molecular and cellular biology.

Functional interaction of c-Ets-1 and GHF-1/Pit-1 mediates Ras activation of pituitary-specific gene expression: mapping of the essential c-Ets-1 domain

B. Wasylyk, A. Gutierrez-Hartmann, A. Bradford, 1995, Molecular and cellular biology.

Structural and functional analysis of the differential effects of c-Jun and v-Jun on prolactin gene expression.

J. Tentler, A. Gutierrez-Hartmann, A. Bradford, 2004, Molecular endocrinology.

Somatostatin acts by inhibiting the cyclic 3',5'-adenosine monophosphate (cAMP)/protein kinase A pathway, cAMP response element-binding protein (CREB) phosphorylation, and CREB transcription potency.

J. Tentler, A. Gutierrez-Hartmann, J. Hadcock, 1997, Molecular endocrinology.

A Pit-1 threonine 220 phosphomimic reduces binding to monomeric DNA sites to inhibit Ras and estrogen stimulation of the prolactin gene promoter.

A. Gutierrez-Hartmann, A. Jean, D. Duval, 2010, Molecular endocrinology.

Ras Signaling and Transcriptional Synergy at a Flexible Ets-1/Pit-1 Composite DNA Element Is Defined by the Assembly of Selective Activation Domains*

A. Gutierrez-Hartmann, A. Jean, D. Duval, 2003, Journal of Biological Chemistry.

The Pit-1 Homeodomain and β-Domain Interact with Ets-1 and Modulate Synergistic Activation of the Rat Prolactin Promoter*

K. Brodsky, A. Gutierrez-Hartmann, A. Bradford, 2000, The Journal of Biological Chemistry.

The Ets dominant repressor En/Erm enhances intestinal epithelial tumorigenesis in ApcMin mice

A. Gutierrez-Hartmann, P. Jedlicka, X. Sui, 2009, BMC Cancer.

Cell-specific expression of transfected brain identifier repetitive DNAs.

J. Baxter, A. Gutierrez-Hartmann, S. Mellon, 1988, Nucleic acids research.

Nuclear and cytoplasmic LIMK1 enhances human breast cancer progression

A. Gutierrez-Hartmann, Brice V. McConnell, K. Koto, 2011, Molecular Cancer.

Insulin activation of rat prolactin promoter activity

A. Gutierrez-Hartmann, C. Keech, 1991, Molecular and Cellular Endocrinology.

Pituitary Ets-1 and GABP bind to the growth factor regulatory sites of the rat prolactin promoter.

A. Gutierrez-Hartmann, R. Schweppe, 2001, Nucleic acids research.

LPS-induced expression of the human IL-1 receptor antagonist gene is controlled by multiple interacting promoter elements.

A. Gutierrez-Hartmann, W. Arend, D. Eidlen, 1994, Journal of immunology.

Differential utilization of transcription activation subdomains by distinct coactivators regulates Pit-1 basal and Ras responsiveness.

A. Gutierrez-Hartmann, A. Jean, Patience Murapa, 2007, Molecular endocrinology.

Transforming growth factor-beta1 inhibits rat prolactin promoter activity in GH4 neuroendocrine cells.

A. Gutierrez-Hartmann, K. N. Farrow, Kathryn N. Farrow, 1999, DNA and cell biology.

A 26-Amino Acid Insertion Domain Defines a Functional Transcription Switch Motif in Pit-1β*

A. Gutierrez-Hartmann, S. E. Diamond, 1996, The Journal of Biological Chemistry.

Lipopolysaccharide and Raf-1 kinase regulate secretory interleukin-1 receptor antagonist gene expression by mutually antagonistic mechanisms

A. Gutierrez-Hartmann, W. Arend, C. Guthridge, 1997, Molecular and cellular biology.

Selective repression of rat prolactin gene by stable expression of dominant-negative ets in GH4 pituitary cells

J. Tentler, A. Gutierrez-Hartmann, A. Bradford, 2003, Endocrine.

Functional Components of Fibroblast Growth Factor (FGF) Signal Transduction in Pituitary Cells

A. Gutierrez-Hartmann, A. Bradford, A. Frazer-Abel, 1997, The Journal of Biological Chemistry.

Editorial: PRL-Releasing Peptide Stimulation of PRL Gene Transcription-Enter AKT.

A. Gutierrez-Hartmann, D. Duval, 2002, Endocrinology.

The 26-Amino Acid ß-Motif of the Pit-1ß Transcription Factor Is a Dominant and Independent Repressor Domain

A. Gutierrez-Hartmann, D. Duval, M. Jonsen, 2009 .

Pit-1beta reduces transcription and CREB-binding protein recruitment in a DNA context-dependent manner.

K. Brodsky, A. Gutierrez-Hartmann, M. Jonsen, 2005, The Journal of endocrinology.

Epidermal growth factor and Ras regulate gene expression in GH4 pituitary cells by separate, antagonistic signal transduction pathways

A. Gutierrez-Hartmann, C. A. Pickett, 1995, Molecular and cellular biology.

Interaction of basal positive and negative transcription elements controls repression of the proximal rat prolactin promoter in nonpituitary cells

A. Gutierrez-Hartmann, S. M. Jackson, D. Williamson, 1992, Molecular and cellular biology.

Combination of osteoinductive bone proteins differentiates mesenchymal C3H/10T1/2 cells specifically to the cartilage lineage

A. Gutierrez-Hartmann, B. Atkinson, J. Benedict, 1997, Journal of cellular biochemistry.

CEBPD suppresses prolactin expression and prolactinoma cell proliferation.

S. Melmed, H. Koeffler, A. Gutierrez-Hartmann, 2011, Molecular endocrinology.

Activation of the prolactin promoter in transfected GH3 cells by posterior pituitary cells.

A. Gutierrez-Hartmann, R. Bigsby, N. Ben-Jonathan, 1994, Endocrinology.

The Pit-1β Domain Dictates Active Repression and Alteration of Histone Acetylation of the Proximal Prolactin Promoter*

A. Gutierrez-Hartmann, S. E. Diamond, 2000, The Journal of Biological Chemistry.

The epithelial-specific ETS transcription factor ESX/ESE-1/Elf-3 modulates breast cancer-associated gene expression.

J. Tentler, A. Gutierrez-Hartmann, Arthur Gutierrez-Hartmann, 2003, DNA and cell biology.

Role of specific protein kinase C isozymes in mediating epidermal growth factor, thyrotropin-releasing hormone, and phorbol ester regulation of the rat prolactin promoter in GH4/GH4C1 pituitary cells.

A. Gutierrez-Hartmann, N. Manning, Y. Akita, 2002, Molecular endocrinology.

ETS transcription factors in endocrine systems

A. Gutierrez-Hartmann, A. Bradford, D. Duval, 2007, Trends in Endocrinology & Metabolism.

THE GROWTH HORMONE GENE FAMILY: STRUCTURE, EVOLUTION, EXPRESSION, AND REGULATION

N. Eberhardt, M. Karin, J. Baxter, 1982 .

Molecular mechanisms of ETS transcription factor-mediated tumorigenesis

A. Gutierrez-Hartmann, Adwitiya Kar, 2013, Critical reviews in biochemistry and molecular biology.

Transcriptional Control of the Cell Cycle in Mammary Gland Development and Tumorigenesis

H. Ford, A. Gutierrez-Hartmann, R. Coletta, 2004, Journal of Mammary Gland Biology and Neoplasia.

Identification of Cytoplasmic Proteins Interacting with the Mammary Cell Transforming Domain of Ese-1

A. Gutierrez-Hartmann, 2008 .

MicroRNAs Regulate Pituitary Development, and MicroRNA 26b Specifically Targets Lymphoid Enhancer Factor 1 (Lef-1), Which Modulates Pituitary Transcription Factor 1 (Pit-1) Expression*

Zichao Zhang, S. Florez, B. Amendt, 2010, The Journal of Biological Chemistry.

The ETS Transcription Factor ESE-1 Transforms MCF-12A Human Mammary Epithelial Cells via a Novel Cytoplasmic Mechanism

Meenakshi Singh, A. Gutierrez-Hartmann, K. Koto, 2004, Molecular and Cellular Biology.

Mechanism Epithelial Cells via a Novel Cytoplasmic Transforms MCF-12 A Human Mammary The ETS Transcription Factor ESE-1

Meenakshi Singh, A. Gutierrez-Hartmann, K. Koto, 2004 .

Ets Transcription Factors

A. Gutierrez-Hartmann, A. Bradford, 2000 .

Control of MicroRNA-21 expression in colorectal cancer cells by oncogenic epidermal growth factor/Ras signaling and Ets transcription factors.

A. Gutierrez-Hartmann, P. Jedlicka, N. Yaghi, 2012, DNA and cell biology.

Signaling pathways regulating pituitary lactotrope homeostasis and tumorigenesis.

A. Gutierrez-Hartmann, Allyson Booth, 2015, Advances in experimental medicine and biology.

Differential ability of various plasmid DNAs to sequester inhibitors of RNA polymerase III transcription.

J. Baxter, A. Gutierrez-Hartmann, 1987, DNA.

Benign mammary epithelial cells enhance the transformed phenotype of human breast cancer cells

J. Tentler, A. Gutierrez-Hartmann, P. Schedin, 2010, BMC Cancer.

Pituitary somatolactotropes evade an oncogenic response to Ras

A. Gutierrez-Hartmann, T. Trudeau, Allyson K. Roof, 2018, Molecular and Cellular Endocrinology.

Preoperative diagnosis of lymphocytic hypophysitis (adenohypophysitis) unresponsive to short course dexamethasone: case report.

A. Gutierrez-Hartmann, K. Lillehei, B. Kleinschmidt-DeMasters, 1992, Neurosurgery.

Distinct genetic alterations in the mitogen-activated protein kinase pathway dictate sensitivity of thyroid cancer cells to mitogen-activated protein kinase kinase 1/2 inhibition.

B. Haugen, A. Gutierrez-Hartmann, Vibha Sharma, 2009, Thyroid : official journal of the American Thyroid Association.

Targeted Intracellular Delivery of Trastuzumab Using Designer Phage Lambda Nanoparticles Alters Cellular Programs in Human Breast Cancer Cells.

A. D’Alessandro, A. Gutierrez-Hartmann, D. Simberg, 2021, ACS nano.

The vanishing physician-scientist?: The culture and politics of health care work

A. Gutierrez-Hartmann, 2010 .

Consider the context: Ras/ERK and PI3K/AKT/mTOR signaling outcomes are pituitary cell type-specific

A. Gutierrez-Hartmann, Allyson K. Roof, 2017, Molecular and Cellular Endocrinology.

ETS transcription factor ESE-1/Elf3 is an independent prognostic factor of survival in HR+HER2+ breast cancer patients

A. Thor, A. Gutierrez-Hartmann, S. Edgerton, 2020, Breast Cancer Research and Treatment.

Structure-function analysis of the rat prolactin promoter: phasing requirements of proximal cell-specific elements.

A. Gutierrez-Hartmann, S. M. Jackson, S. Siddiqui, 1991, Molecular endocrinology.

Identification of cis-acting promoter elements important for expression of the mouse glycoprotein hormone alpha-subunit gene in thyrotropes.

V. Sarapura, A. Gutierrez-Hartmann, W. Wood, 1990, Molecular endocrinology.

Purification and Mass Spectrometric Identification of GA-binding Protein (GABP) as the Functional Pituitary Ets Factor Binding to the Basal Transcription Element of the Prolactin Promoter*

K. Resing, N. Ahn, K. Brodsky, 2003, The Journal of Biological Chemistry.

Role of Helix-Loop-Helix Proteins in Gonadotropin Gene Expression

K. Barnhart, A. Gutierrez-Hartmann, J. Hoeffler, 1994 .

Analysis of rat prolactin promoter sequences that mediate pituitary-specific and 3',5'-cyclic adenosine monophosphate-regulated gene expression in vivo.

A. Gutierrez-Hartmann, C. Keech, 1989, Molecular endocrinology.

Conserved mechanisms of Ras regulation of evolutionary related transcription factors, Ets1 and Pointed P2

B. Wasylyk, A. Gutierrez-Hartmann, A. Bradford, 1997, Oncogene.

PRL-releasing peptide stimulation of PRL gene transcription--enter AKT.

A. Gutierrez-Hartmann, D. Duval, 2002, Endocrinology.

Ras mediates Src but not epidermal growth factor-receptor tyrosine kinase signaling pathways in GH4 neuroendocrine cells.

A. Gutierrez-Hartmann, C. A. Pickett, 1994, Proceedings of the National Academy of Sciences of the United States of America.

The Ras and protein kinase C signaling pathways are functionally antagonistic in GH4 neuroendocrine cells.

A. Gutierrez-Hartmann, K. Conrad, J. M. Oberwetter, 1993, Molecular endocrinology.

Ets transcription factors in intestinal morphogenesis, homeostasis and disease.

A. Gutierrez-Hartmann, P. Jedlicka, 2008, Histology and histopathology.

The 26-amino acid beta-motif of the Pit-1beta transcription factor is a dominant and independent repressor domain.

A. Gutierrez-Hartmann, D. Duval, M. Jonsen, 2009, Molecular endocrinology.

Structural characterization of the PIT-1/ETS-1 interaction: PIT-1 phosphorylation regulates PIT-1/ETS-1 binding

R. Kaptein, A. Gutierrez-Hartmann, D. Duval, 2002, Proceedings of the National Academy of Sciences of the United States of America.

The Balance of PI3K and ERK Signaling Is Dysregulated in Prolactinoma and Modulated by Dopamine.

H. Kiyokawa, A. Gutierrez-Hartmann, S. Jirawatnotai, 2018, Endocrinology.

Upstream stimulatory factor, a basic-helix-loop-helix-zipper protein, regulates the activity of the alpha-glycoprotein hormone subunit gene in pituitary cells.

A. Gutierrez-Hartmann, J. Hoeffler, S. M. Jackson, 1995, Molecular endocrinology.

ESE-1 is Required to Maintain the Transformed Phenotype of MCF-7 and ZR-75-1 Human Breast Cancer Cells

H. Horita, A. Gutierrez-Hartmann, J. Poczobutt, 2010 .

Elucidation of Homeoprotein Cart‐1 Function during In Vitro Chondrogenesis of C3H10T1/2 Micromass Cultures

A. Gutierrez-Hartmann, B. Atkinson, J. Benedict, 1996, Annals of the New York Academy of Sciences.

ESE-1 Knockdown Attenuates Growth in Trastuzumab-resistant HER2+ Breast Cancer Cells.

Bolin Liu, A. Gutierrez-Hartmann, Adwitiya Kar, 2017, Anticancer research.

ESE-1/ELF3 mRNA expression associates with poor survival outcomes in HER2+ breast cancer patients and is critical for tumorigenesis in HER2+ breast cancer cells

A. Gutierrez-Hartmann, Adwitiya Kar, 2017, Oncotarget.

Human IL-1 receptor antagonist promoter. Cell type-specific activity and identification of regulatory regions.

M. T. Brewer, A. Gutierrez-Hartmann, W. Arend, 1992, Journal of immunology.

Protein factors in thyrotropic tumor nuclear extracts bind to a region of the mouse thyrotropin beta-subunit promoter essential for expression in thyrotropes.

A. Gutierrez-Hartmann, W. Wood, E. Ridgway, 1990, Molecular endocrinology.

Identification of thyrotroph-specific factors and cis-acting sequences of the murine thyrotropin beta subunit gene.

A. Gutierrez-Hartmann, W. Wood, E. Ridgway, 1989, Molecular endocrinology.

The Ets dominant repressor En/Erm enhances intestinal epithelial tumorigenesis in ApcMin mice

A. Gutierrez-Hartmann, P. Jedlicka, X. Sui, 2009 .

Activation of the murine thyrotropin beta-subunit promoter by GH4 rat pituitary cell-free extracts.