S. Korsmeyer

发表

BCL-2 family: regulators of cell death.

D. Chao, S. Korsmeyer, S J Korsmeyer, 1998, Annual review of immunology.

BID: a novel BH3 domain-only death agonist.

C. Milliman, D. Chao, S. Korsmeyer, 1996, Genes & development.

Bcl-2 initiates a new category of oncogenes: regulators of cell death.

S. Korsmeyer, 1992, Blood.

Differentiation and cell death: lessons from the immune system.

G. Linette, S. Korsmeyer, 1994, Current opinion in cell biology.

Evidence for involvement of Bax and p53, but not caspases, in radiation‐induced cell death of cultured postnatal hippocampal neurons

Mark D. Johnson, S. London, M. Mayberg, 1998, Journal of neuroscience research.

Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

S. Korsmeyer, M. Vila, R. Djaldetti, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Reactive oxygen species and the regulation of cell death by the Bcl-2 gene family.

Z. Oltvai, G. Linette, S. Korsmeyer, 1995, Biochimica et biophysica acta.

p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD

M. Mann, S. Korsmeyer, J. Andersen, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Expression During Murine Development

S. Korsmeyer, D. Novack, 2007 .

Peripheral T-cell lymphoma in lckpr-bcl-2 transgenic mice.

G. Linette, J. Hess, S. Korsmeyer, 1995, Blood.

BCL-XL-regulated apoptosis in T cell development.

D. Chao, S. Korsmeyer, 1997, International immunology.

Biochemical and Genetic Analysis of the Mitochondrial Response of Yeast to BAX and BCL-X L

M. Bassik, J. Jockel, S. Korsmeyer, 2000 .

Interleukln 7-dependent B Lymphocyte Precursor Cells Are Ultrasensitive to Apoptmis

D. Goodhead, E. Wright, S. Korsmeyer, 2003 .

Adenovirus E1B 19-kDa Death Suppressor Protein Interacts with Bax but Not with Bad*

P. Branton, E. Yang, S. Korsmeyer, 1996, The Journal of Biological Chemistry.

BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases.

J. Xiang, D. Chao, S. Korsmeyer, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)

T. McDonnell, S. Korsmeyer, 1991, Nature.

Neurotrophins Support the Development of Diverse Sensory Axon Morphologies

W D Snider, W. Snider, C. Knudson, 1999, The Journal of Neuroscience.

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

R. Schreiber, C. Milliman, G. Núñez, 1990, Nature.

Chloroquine‐Induced Neuronal Cell Death Is p53 and Bcl‐2 Family‐Dependent But Caspase‐Independent

R. Schmidt, R. Flavell, K. Roth, 2001, Journal of neuropathology and experimental neurology.

Bax Involvement in p53-Mediated Neuronal Cell Death

P. Schwartzkroin, C. Knudson, S. Korsmeyer, 1998, The Journal of Neuroscience.

Bcl-2 maintains B cell memory

S. Korsmeyer, T. McDonnell, G. Núñez, 1991, Nature.

Detection of the apoptosis-suppressing oncoprotein bc1-2 in hormone-refractory human prostate cancers.

D. Chopin, M. Colombel, M. Benson, 1993, The American journal of pathology.

Regulators of cell death.

S. Korsmeyer, 1995, Trends in genetics : TIG.

Apoptotic death of lymphocytes in murine acquired immunodeficiency syndrome: Involvement of Fas‐Fas ligand interaction

S. Korsmeyer, S. Korsmeyer, J. Russell, 1995, European journal of immunology.

Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points.

G. Linette, L. Glimcher, S. Hedrick, 1994, Immunity.

Bcl-XL and Bcl-2 repress a common pathway of cell death

G. Linette, C. Thompson, L. Boise, 1995, The Journal of experimental medicine.

Human bcl-2 Gene Attenuates the Ability of Rabbit Lens Epithelial Cells against H2O2-induced Apoptosis through Down-regulation of the αB-crystallin Gene*

H. Xiang, S. Korsmeyer, J. Reddan, 2001, The Journal of Biological Chemistry.

BAX Contributes to Apoptotic-Like Death Following Neonatal Hypoxia-Ischemia: Evidence for Distinct Apoptosis Pathways

D. Holtzman, C. Knudson, Junjeong Choi, 2001, Molecular medicine.

Differences in Bcl‐2‐ and Bax‐independent function in regulating apoptosis in sensory neuron populations

A. Davies, G. Middleton, S. Korsmeyer, 2000, The European journal of neuroscience.

Errors of homeostasis and deregulated apoptosis.

S. Korsmeyer, J. Rinkenberger, 1997, Current opinion in genetics & development.

BCL-2 gene family and the regulation of programmed cell death.

S. Korsmeyer, 1995, Cancer research.

Mcl-1 deficiency results in peri-implantation embryonic lethality.

K. Roth, B. Klocke, S. Korsmeyer, 2000, Genes & development.

Phosphorylation of BCL‐2 regulates ER Ca2+ homeostasis and apoptosis

Tullio Pozzan, Luca Scorrano, S. Korsmeyer, 2004, The EMBO journal.

Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation.

G. Linette, S. Korsmeyer, Y. Li, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Developmental regulation of the Bcl‐2 protein and susceptibility to cell death in B lymphocytes.

L. Ding, G. Núñez, S. Korsmeyer, 1994, The EMBO journal.

Enhanced Oxidative Stress and Altered Antioxidants in Brains of Bcl‐2‐Deficient Mice

S. Korsmeyer, I. Ziv, E. Melamed, 1998, Journal of neurochemistry.

Tuberin activates the proapoptotic molecule BAD

G. Krupitza, M. Rosner, S. Korsmeyer, 2006, Oncogene.

BID mediates neuronal cell death after oxygen/ glucose deprivation and focal cerebral ischemia

N. Plesnila, M. Moskowitz, D. Kohane, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Phase I trial and clinical pharmacology of 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl)-1-nitrosourea.

P. Woolley, P. Schein, S. Korsmeyer, 1981, Cancer research.

BCL-2 family members and the mitochondria in apoptosis.

S. Korsmeyer, A. Gross, J. M. McDonnell, 1999, Genes & development.

Motor neuron degeneration is attenuated in bax‐deficient neurons in vitro

J. Rothstein, S. Korsmeyer, M. Knudson, 1999, Journal of neuroscience research.

Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction

S. Korsmeyer, J. Tilly, C. Knudson, 1997, Nature Medicine.

Caspase-2 deficiency prevents programmed germ cell death resulting from cytokine insufficiency but not meiotic defects caused by loss of ataxia telangiectasia-mutated (Atm) gene function

S. Korsmeyer, Y. Taketani, J. Tilly, 2001, Cell Death and Differentiation.

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.

S. Korsmeyer, S. Korsmeyer, W. Hickey, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Bcl-2 protein expression during murine development.

S. Korsmeyer, S. Korsmeyer, D. Novack, 1994, The American journal of pathology.

Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A.

Susan S. Taylor, M. Mann, S. Korsmeyer, 1999, Molecular cell.

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis.

S. Korsmeyer, T. Mak, E. Cheng, 2001, Molecular cell.

Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis.

S. Korsmeyer, J. Zha, M. Wei, 2000, Science.

tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c.

V. Mootha, S. Korsmeyer, M. Ashiya, 2000, Genes & development.

Molecular rearrangements of the MLL gene are present in most cases of infant acute myeloid leukemia and are strongly correlated with monocytic or myelomonocytic phenotypes.

I. Bernstein, P. Sorensen, S. Korsmeyer, 1994, The Journal of clinical investigation.

Prevention of lymphocyte cell death in sepsis improves survival in mice.

S. Korsmeyer, R. Hotchkiss, J. Cobb, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Development expression of Hox11 and specification of splenic cell fate.

S. Korsmeyer, C. Roberts, S. Korsmeyer, 1995, The American journal of pathology.

Multiple Bcl-2 family members demonstrate selective dimerizations with Bax.

Z. Oltvai, S. Korsmeyer, C. Thompson, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Isolation of single-copy human genes from a library of yeast artificial chromosome clones.

D. Schlessinger, S. Korsmeyer, M. Olson, 1989, Science.

Deregulated Bcl-2-immunoglobulin transgene expands a resting but responsive immunoglobulin M and D-expressing B-cell population

S. Korsmeyer, T. McDonnell, G. Núñez, 1990, Molecular and cellular biology.

Immunolocalization of the Bcl-2 protein within hematopoietic neoplasms.

S. Korsmeyer, S. Korsmeyer, D. Hockenbery, 1991, Blood.

Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c

S. Korsmeyer, M. Wei, M. Saito, 2000, Cell Death and Differentiation.

Inhibition of virus-induced neuronal apoptosis by Bax

S. Korsmeyer, S. Korsmeyer, G. Oyler, 1999, Nature Medicine.

Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2.

G Waksman, S. Korsmeyer, G. Waksman, 1997, Proceedings of the National Academy of Sciences of the United States of America.

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.

S. Korsmeyer, J. Golden, G. Evan, 2000, Molecular cell.

Widespread Elimination of Naturally Occurring Neuronal Death inBax-Deficient Mice

S. Korsmeyer, C. Keller-Peck, W. Snider, 1998, The Journal of Neuroscience.

Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines.

S. Korsmeyer, G. Núñez, S. Korsmeyer, 1990, Journal of immunology.

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

S. Korsmeyer, T. Dyke, C. Knudson, 1997, Nature.

Hematopoietic malignancies demonstrate loss-of-function mutations of BAX.

S. Korsmeyer, G. Waksman, J. Meijerink, 1998, Blood.

Bax accelerates tumorigenesis in p53-deficient mice.

S. Korsmeyer, Y. Lin, C. Knudson, 2001, Cancer research.

Heterodimerization with Bax is required for Bcl-2 to repress cell death.

Z. Oltvai, S. Korsmeyer, S. Korsmeyer, 1995, Current topics in microbiology and immunology.

Bax-Dependent Spermatogonia Apoptosis Is Required for Testicular Development and Spermatogenesis1

S. Korsmeyer, C. Knudson, L. Russell, 2002, Biology of reproduction.

bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS.

S. Korsmeyer, D. Merry, S. Korsmeyer, 1994, Development.

Alternative promoters and exons, somatic mutation and deregulation of the Bcl‐2‐Ig fusion gene in lymphoma.

S. Korsmeyer, U. Jaeger, M. Seto, 1988, The EMBO journal.

Growth- and tumor-promoting effects of deregulated BCL2 in human B-lymphoblastoid cells.

S. Korsmeyer, M. Seto, G. Núñez, 1989, Proceedings of the National Academy of Sciences of the United States of America.

A chemical genomics approach toward understanding the global functions of the target of rapamycin protein (TOR).

M. Johnston, L. Riles, S. Korsmeyer, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Combination chemotherapy for locally advanced pancreatic cancer: equivalence to external beam irradiation and implication for future management.

D. Stablein, P. Woolley, P. Schein, 1983, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death.

Z. Oltvai, S. Korsmeyer, J. Shutter, 1993, Seminars in cancer biology.

Chromosomal translocations in lymphoid malignancies reveal novel proto-oncogenes.

S. Korsmeyer, S. Korsmeyer, 1992, Annual review of immunology.

Targeting of Bcl-2 to the mitochondrial outer membrane by a COOH-terminal signal anchor sequence.

S. Korsmeyer, S. Korsmeyer, G. Shore, 1993, The Journal of biological chemistry.

BAX enhances paclitaxel-induced apoptosis through a p53-independent pathway.

S. Korsmeyer, S. Cannistra, S. Korsmeyer, 1996, Proceedings of the National Academy of Sciences of the United States of America.

A negative regulatory element in the bcl-2 5'-untranslated region inhibits expression from an upstream promoter

S. Korsmeyer, S. Korsmeyer, R. L. Young, 1993, Molecular and cellular biology.

MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis.

R. D. Hanson, S. Korsmeyer, J. Hess, 1998, Proceedings of the National Academy of Sciences of the United States of America.

bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis.

S. Korsmeyer, S. Lowe, M. McCurrach, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Defects in yolk sac hematopoiesis in Mll-null embryos.

S. Korsmeyer, J. Hess, S. Korsmeyer, 1997, Blood.

Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis.

S. Korsmeyer, R. Hotchkiss, J. Cobb, 1999, Journal of immunology.

Expression of Bcl-2 and Bcl-2-Ig fusion transcripts in normal and neoplastic cells.

S. Korsmeyer, M. Seto, W. Graninger, 1987, The Journal of clinical investigation.

Role of membrane anchor domain of Bcl-2 in suppression of apoptosis caused by E1B-defective adenovirus.

Z. Oltvai, S. Korsmeyer, P. Branton, 1994, The Journal of biological chemistry.

Untangling the web: mitochondrial fission and apoptosis.

S. Korsmeyer, S. Oakes, S. Korsmeyer, 2004, Developmental cell.

Suppression of developmental retinal cell death but not of photoreceptor degeneration in Bax-deficient mice.

S. Korsmeyer, C. Knudson, S. Korsmeyer, 1998, Investigative ophthalmology & visual science.

Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development.

R. D. Hanson, S. Korsmeyer, F. Ruddle, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Hyperglycemia induces apoptosis in pre-implantation embryos through cell death effector pathways

S. Korsmeyer, C. Knudson, S. Korsmeyer, 1998, Nature Medicine.

Bcl-2 initiates a new category of oncogenes: regulators of cell death.

S. Korsmeyer, S J Korsmeyer, 1992, Blood.

Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes.

S. Korsmeyer, S. Korsmeyer, C. Sentman, 1993, Journal of immunology.

A major human immunodeficiency virus type 1-initiated killing pathway distinct from apoptosis

S. Korsmeyer, S. Korsmeyer, A. Riva, 1997, Journal of virology.

Constitutive expression of human Bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis.

S. Korsmeyer, K. Kohn, P. O'Connor, 1993, Cancer research.

BCLW mediates survival of postmitotic Sertoli cells by regulating BAX activity.

S. Korsmeyer, C. Thompson, C. Knudson, 2001, Developmental biology.