Chuen-Mao Yang

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High Glucose Induces Reactive Oxygen Species-Dependent Matrix Metalloproteinase-9 Expression and Cell Migration in Brain Astrocytes

H. Hsieh, Chih‐Chung Lin, L. Hsiao, 2013, Molecular Neurobiology.

Tumor necrosis factor-α induces MMP-9 expression via p 42 / p 44 MAPK , JNK , and nuclear factor-κ B in A 549 cells

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2008 .

Tumor necrosis factor-alpha induces MMP-9 expression via p42/p44 MAPK, JNK, and nuclear factor-kappaB in A549 cells.

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2008, Toxicology and applied pharmacology.

Interleukin‐1β induces MMP‐9 expression via p42/p44 MAPK, p38 MAPK, JNK, and nuclear factor‐κB signaling pathways in human tracheal smooth muscle cells

Chih‐Chung Lin, Chuen-Mao Yang, Chiang-Wen Lee, 2007 .

Involvement of MAPKs and NF-kappaB in LPS-induced VCAM-1 expression in human tracheal smooth muscle cells.

Chuen-Mao Yang, Chiang-Wen Lee, Wei-Ning Lin, 2007, Cellular signalling.

Involvement of p42/p44 MAPK, JNK, and NF‐κB in IL‐1β‐induced ICAM‐1 expression in human pulmonary epithelial cells

Chih‐Chung Lin, Chuen-Mao Yang, F. Lin, 2005 .

Involvement of p42/p44 MAPK, p38 MAPK, JNK, and NF-κB in IL-1β-induced VCAM-1 expression in human tracheal smooth muscle cells

Chih‐Chung Lin, Chuen-Mao Yang, Chiang-Wen Lee, 2005 .

Involvement of p42/p44 MAPK, p38 MAPK, JNK and nuclear factor‐kappa B in interleukin‐1β‐induced matrix metalloproteinase‐9 expression in rat brain astrocytes

H. Hsieh, Chuen-Mao Yang, Cheng-Ying Wu, 2004, Journal of neurochemistry.

Carbon Monoxide Releasing Molecule-3 Enhances Heme Oxygenase-1 Induction via ROS-Dependent FoxO1 and Nrf2 in Brain Astrocytes

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2021, Oxidative medicine and cellular longevity.

Bradykinin induces matrix metalloproteinase‐9 expression and cell migration through a PKC‐δ‐dependent ERK/Elk‐1 pathway in astrocytes

H. Hsieh, Chuen-Mao Yang, Cheng-Ying Wu, 2008, Glia.

HO-1 Upregulation by Kaempferol via ROS-Dependent Nrf2-ARE Cascade Attenuates Lipopolysaccharide-Mediated Intercellular Cell Adhesion Molecule-1 Expression in Human Pulmonary Alveolar Epithelial Cells

L. Hsiao, Chuen-Mao Yang, Wei-Ning Lin, 2022, Antioxidants.

Tumor necrosis factor-alpha induces VCAM-1-mediated inflammation via c-Src-dependent transactivation of EGF receptors in human cardiac fibroblasts

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2015, Journal of Biomedical Science.

Overexpression of HO-1 protects against TNF-alpha-mediated airway inflammation by down-regulation of TNFR1-dependent oxidative stress.

Chih‐Chung Lin, Chuen-Mao Yang, Chiang-Wen Lee, 2009, The American journal of pathology.

Overexpression of HO-1 protects against TNF-alpha-mediated airway inflammation by down-regulation of TNFR1-dependent oxidative stress

Chuen-Mao Yang, I-Ta Lee, 2010 .

RTA 408 Inhibits Interleukin-1β-Induced MMP-9 Expression via Suppressing Protein Kinase-Dependent NF-κB and AP-1 Activation in Rat Brain Astrocytes

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2019, International journal of molecular sciences.

Haem oxygenase‐1 up‐regulation by rosiglitazone via ROS‐dependent Nrf2‐antioxidant response elements axis or PPARγ attenuates LPS‐mediated lung inflammation

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2018, British journal of pharmacology.

IL‐1β induces MMP‐9 expression via a Ca2+‐dependent CaMKII/JNK/c‐JUN cascade in rat brain astrocytes

H. Hsieh, Chuen-Mao Yang, Cheng-Ying Wu, 2009, Glia.

Protein Kinase C-δ Transactivates Platelet-derived Growth Factor Receptor-α in Mechanical Strain-induced Collagenase 3 (Matrix Metalloproteinase-13) Expression by Osteoblast-like Cells*

C. Tseng, H. Hsieh, L. Hsiao, 2009, The Journal of Biological Chemistry.

Cigarette smoke particle-phase extract induces HO-1 expression in human tracheal smooth muscle cells: role of the c-Src/NADPH oxidase/MAPK/Nrf2 signaling pathway.

Chih‐Chung Lin, Chuen-Mao Yang, I-Ta Lee, 2010, Free radical biology & medicine.

TNF‐α induces matrix metalloproteinase‐9 expression in A549 cells: Role of TNFR1/TRAF2/PKCα‐dependent signaling pathways

Chih‐Chung Lin, Chuen-Mao Yang, I-Ta Lee, 2010, Journal of cellular physiology.

Cardiovascular , Pulmonary and Renal Pathology Overexpression of HO-1 Protects against TNF-- Mediated Airway Inflammation by Down-Regulation of TNFR 1-Dependent Oxidative Stress

Chih‐Chung Lin, Chuen-Mao Yang, Chiang-Wen Lee, 2010 .

Induction of COX-2/PGE(2)/IL-6 is crucial for cigarette smoke extract-induced airway inflammation: Role of TLR4-dependent NADPH oxidase activation.

Chih‐Chung Lin, Chuen-Mao Yang, Chiang-Wen Lee, 2010, Free Radical Biology & Medicine.

Lipoteichoic Acid Induces HO-1 Expression via the TLR2/MyD88/c-Src/NADPH Oxidase Pathway and Nrf2 in Human Tracheal Smooth Muscle Cells1

Chih‐Chung Lin, Chuen-Mao Yang, Chiang-Wen Lee, 2008, The Journal of Immunology.

Smooth Muscle Cells Pathway and Nrf2 in Human Tracheal via the TLR2/MyD88/c-Src/NADPH Oxidase Lipoteichoic Acid Induces HO-1 Expression

Chih‐Chung Lin, Chuen-Mao Yang, Chiang-Wen Lee, 2008 .

Diminished COX-2/PGE2-Mediated Antiviral Response Due to Impaired NOX/MAPK Signaling in G6PD-Knockdown Lung Epithelial Cells

Chuen-Mao Yang, D. Chiu, Yi-Hsuan Wu, 2016, PloS one.

Bradykinin‐mediated cell proliferation depends on transactivation of EGF receptor in corneal fibroblasts

Chuen-Mao Yang, Ching-Yi Cheng, H. Tseng, 2012, Journal of cellular physiology.

Resveratrol inhibits BK‐induced COX‐2 transcription by suppressing acetylation of AP‐1 and NF‐&kgr;B in human rheumatoid arthritis synovial fibroblasts

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2017, Biochemical pharmacology.

EV71 induces COX‐2 expression via c‐Src/PDGFR/PI3K/Akt/p42/p44 MAPK/AP‐1 and NF‐κB in rat brain astrocytes

H. Hsieh, Chuen-Mao Yang, I-Ta Lee, 2010, Journal of cellular physiology.

Lipopolysaccharide induces ICAM-1 expression via a c-Src/NADPH oxidase/ROS-dependent NF-κB pathway in human pulmonary alveolar epithelial cells.

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2016, American journal of physiology. Lung cellular and molecular physiology.

Kainic Acid‐Induced Neurotrophic Activities in Developing Cortical Neurons

Chuen-Mao Yang, Yi-Hsuan Lee, C. Chiu, 2000, Journal of neurochemistry.

Induction of heme oxygenase-1 attenuates lipopolysaccharide-induced cyclooxygenase-2 expression in mouse brain endothelial cells

Chuen-Mao Yang, Ruey-Horng Shih, 2010, Journal of Neuroinflammation.

Up‐regulation of PYK2/PKCα‐dependent haem oxygenase‐1 by CO‐releasing molecule‐2 attenuates TNF‐α‐induced lung inflammation

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2017, British journal of pharmacology.

Transforming growth factor-β1 induces matrix metalloproteinase-9 and cell migration in astrocytes: roles of ROS-dependent ERK- and JNK-NF-κB pathways

H. Hsieh, Chuen-Mao Yang, Wen-Bin Wu, 2010, Journal of Neuroinflammation.

The role of matrix metalloproteinase-9 in pro-inflammatory factors-induced brain inflammation and neurodegenerative diseases

H. Hsieh, Chuen-Mao Yang, 2014 .

Tumor Necrosis Factor-α Enhances Neutrophil Adhesiveness: Induction of Vascular Cell Adhesion Molecule-1 via Activation of Akt and CaM Kinase II and Modifications of Histone Acetyltransferase and Histone Deacetylase 4 in Human Tracheal Smooth Muscle Cells

W. Aird, Chih‐Chung Lin, Chuen-Mao Yang, 2008, Molecular Pharmacology.

transactivation in A549 cells

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2010 .

IL‐1β induces expression of matrix metalloproteinase‐9 and cell migration via a c‐Src‐dependent, growth factor receptor transactivation in A549 cells

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2010, British journal of pharmacology.

Induction of HO-1 by Mevastatin Mediated via a Nox/ROS-Dependent c-Src/PDGFRα/PI3K/Akt/Nrf2/ARE Cascade Suppresses TNF-α-Induced Lung Inflammation

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2020, Journal of clinical medicine.

Thrombin Enhanced Matrix Metalloproteinase-9 Expression and Migration of SK-N-SH Cells via PAR-1, c-Src, PYK2, EGFR, Erk1/2 and AP-1

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2016, Molecular Neurobiology.

Thrombin/Matrix Metalloproteinase-9-Dependent SK-N-SH Cell Migration is Mediated Through a PLC/PKC/MAPKs/NF-κB Cascade

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2015, Molecular Neurobiology.

PAR1‐dependent COX‐2/PGE2 production contributes to cell proliferation via EP2 receptors in primary human cardiomyocytes

H. Hsieh, Chuen-Mao Yang, Pei-Ling Chi, 2014, British journal of pharmacology.

Enterovirus 71 induces integrin β1/EGFR‐Rac1‐dependent oxidative stress in SK‐N‐SH cells: Role of HO‐1/CO in viral replication

H. Hsieh, Chuen-Mao Yang, I-Ta Lee, 2011, Journal of cellular physiology.

NADPH oxidase-mediated redox signal contributes to lipoteichoic acid-induced MMP-9 upregulation in brain astrocytes

H. Hsieh, Chih‐Chung Lin, L. Hsiao, 2012, Journal of Neuroinflammation.

Chinese Herbs and Repurposing Old Drugs as Therapeutic Agents in the Regulation of Oxidative Stress and Inflammation in Pulmonary Diseases

Chuen-Mao Yang, Chien-Chung Yang, 2021, Journal of inflammation research.

High-Glucose-Derived Oxidative Stress-Dependent Heme Oxygenase-1 Expression from Astrocytes Contributes to the Neuronal Apoptosis

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2016, Molecular Neurobiology.

Deletion of the FHL2 gene attenuates the formation of atherosclerotic lesions after a cholesterol-enriched diet.

Chuen-Mao Yang, H. Yeh, P. Chu, 2010, Life sciences.

Functional coupling expression of COX-2 and cPLA2 induced by ATP in rat vascular smooth muscle cells: role of ERK1/2, p38 MAPK, and NF-kappaB.

Chih‐Chung Lin, Chuen-Mao Yang, Wei-Ning Lin, 2009, Cardiovascular research.

Reactive Oxygen Species-Dependent c-Fos/Activator Protein 1 Induction Upregulates Heme Oxygenase-1 Expression by Bradykinin in Brain Astrocytes.

H. Hsieh, Chuen-Mao Yang, Cheng-Ying Wu, 2010, Antioxidants & redox signaling.

Anti-Inflammatory Effects of Rhamnetin on Bradykinin-Induced Matrix Metalloproteinase-9 Expression and Cell Migration in Rat Brain Astrocytes

L. Hsiao, Chuen-Mao Yang, Chien-Chung Yang, 2022, International journal of molecular sciences.

Neuroprotective Effects of Dehydroepiandrosterone Sulfate Through Inhibiting Expression of Matrix Metalloproteinase-9 from Bradykinin-Challenged Astroglia

Pei-Shan Liu, Tsong-Hai Lee, H. Hsieh, 2018, Molecular Neurobiology.

IL-1β Induces MMP-9-Dependent Brain Astrocytic Migration via Transactivation of PDGF Receptor/NADPH Oxidase 2-Derived Reactive Oxygen Species Signals

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2014, Molecular Neurobiology.

Multiple Factors from Bradykinin-Challenged Astrocytes Contribute to the Neuronal Apoptosis: Involvement of Astroglial ROS, MMP-9, and HO-1/CO System

H. Hsieh, Chih‐Chung Lin, L. Hsiao, 2013, Molecular Neurobiology.

NADPH oxidase 2-derived reactive oxygen species signal contributes to bradykinin-induced matrix metalloproteinase-9 expression and cell migration in brain astrocytes

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2012, Cell Communication and Signaling.

Oxidized low‐density lipoprotein induces matrix metalloproteinase‐9 expression via a p42/p44 and JNK‐dependent AP‐1 pathway in brain astrocytes

H. Hsieh, Chuen-Mao Yang, Cheng-Ying Wu, 2009, Glia.

Oxidized Low-Density Lipoprotein-Induced Matrix Metalloproteinase-9 Expression via PKC-δ/p42/p44 MAPK/Elk-1 Cascade in Brain Astrocytes

H. Hsieh, Chuen-Mao Yang, Cheng-Ying Wu, 2009, Neurotoxicity research.

Mechanisms underlying oxidized low‐density lipoprotein‐induced matrix metalloproteinase‐9 expression in astrocytes

Chuen-Mao Yang, Hui-Hsin Wang, 2007 .

Up-regulation of ROS-Dependent Matrix Metalloproteinase-9 from High-Glucose-Challenged Astrocytes Contributes to the Neuronal Apoptosis

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2014, Molecular Neurobiology.

Substance P-induced activation of p42/44 mitogen-activated protein kinase associated with cell proliferation in human tracheal smooth muscle cells.

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2002, Cellular signalling.

Participation of lipopolysaccharide in hyperplasic adipose expansion: Involvement of NADPH oxidase/ROS/p42/p44 MAPK‐dependent Cyclooxygenase‐2

Kuo-Yang Huang, Chuen-Mao Yang, Wei-Ning Lin, 2022, Journal of cellular and molecular medicine.

Lipopolysaccharide promoted proliferation and adipogenesis of preadipocytes through JAK/STAT and AMPK-regulated cPLA2 expression

Kuo-Yang Huang, Chuen-Mao Yang, Wei-Ning Lin, 2019, International journal of medical sciences.

Thrombin induces ICAM-1 expression in human lung epithelial cells via c-Src/PDGFR/PI3K/Akt-dependent NF-κB/p300 activation.

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2014, Clinical science.

AdipoR-increased intracellular ROS promotes cPLA2 and COX-2 expressions via activation of PKC and p300 in adiponectin-stimulated human alveolar type II cells.

Chuen-Mao Yang, Wei-Ning Lin, Chi-Sheng Wu, 2016, American journal of physiology. Lung cellular and molecular physiology.

Tumour necrosis factor- a - and interleukin-1 b -stimulated cell proliferation through activation of mitogen-activated protein kinase in canine tracheal smooth muscle cells

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2022 .

20‐Hydroxyeicosatetraenoic acid inhibits ATP‐induced COX‐2 expression via peroxisome proliferator activator receptor‐α in vascular smooth muscle cells

C. Tseng, Chuen-Mao Yang, chan-Jung liang, 2011, British journal of pharmacology.

via Toll-like receptor 2 in tracheal smooth muscle cells Lipoteichoic acid-stimulated p42/p44 MAPK activation

Chuen-Mao Yang, Chiang-Wen Lee, C. Chien, 2016 .

Enterovirus 71 modulates a COX‐2/PGE2/cAMP‐dependent viral replication in human neuroblastoma cells: Role of the c‐Src/EGFR/p42/p44 MAPK/CREB signaling pathway

H. Hsieh, Chuen-Mao Yang, I-Ta Lee, 2011, Journal of cellular biochemistry.

Interleukin‐1β induces ICAM‐1 expression enhancing leukocyte adhesion in human rheumatoid arthritis synovial fibroblasts: Involvement of ERK, JNK, AP‐1, and NF‐κB

H. Hsieh, Chih‐Chung Lin, L. Hsiao, 2010, Journal of cellular physiology.

Lipoteichoic Acid Induces Matrix Metalloproteinase-9 Expression via Transactivation of PDGF Receptors and NF-κB Activation in Rat Brain Astrocytes

H. Hsieh, Chuen-Mao Yang, Cheng-Ying Wu, 2010, Neurotoxicity Research.

Sphingosine 1‐phosphate induces EGFR expression via Akt/NF‐κB and ERK/AP‐1 pathways in rat vascular smooth muscle cells

H. Hsieh, Chuen-Mao Yang, Cheng-Ying Wu, 2008 .

EV71 induces VCAM-1 expression via PDGF receptor, PI3-K/Akt, p38 MAPK, JNK and NF-kappaB in vascular smooth muscle cells.

H. Hsieh, Chuen-Mao Yang, J. Horng, 2007, Cellular signalling.

IL‐1β‐induced expression of cytosolic phospholipase A2 in human synovial fibroblast of rheumatoid arthritis

Chuen-Mao Yang, Pei-Ling Chi, 2007 .

Sphingosine‐1‐phosphate induces COX‐2 expression via PI3K/Akt and p42/p44 MAPK pathways in rat vascular smooth muscle cells

H. Hsieh, Chuen-Mao Yang, Chou-Bing Wu, 2006, Journal of cellular physiology.

Transcriptional regulation of VCAM‐1 expression by tumor necrosis factor‐α in human tracheal smooth muscle cells: Involvement of MAPKs, NF‐κB, p300, and histone acetylation

J. Pouysségur, Chih‐Chung Lin, Chuen-Mao Yang, 2006 .

OxLDL induces mitogen-activated protein kinase activation mediated via PI3-kinase/Akt in vascular smooth muscle cells Published, JLR Papers in Press, June 16, 2003. DOI 10.1194/jlr.M300006-JLR200

L. Hsiao, Chuen-Mao Yang, C. Chien, 2003, Journal of Lipid Research.

Upregulation of COX-2 and PGE2 Induced by TNF-α Mediated Through TNFR1/MitoROS/PKCα/P38 MAPK, JNK1/2/FoxO1 Cascade in Human Cardiac Fibroblasts

L. Hsiao, Chuen-Mao Yang, Chien-Chung Yang, 2021, Journal of inflammation research.

5,8-Dihydroxy-4 ′, 7-dimethoxyflavone Attenuates TNF-α-Induced Expression of Vascular Cell Adhesion Molecule-1 through EGFR/PKCα/PI3K/Akt/Sp1-Dependent Induction of Heme Oxygenase-1 in Human Cardiac Fibroblasts

L. Hsiao, Chuen-Mao Yang, Chien-Chung Yang, 2022, Oxidative medicine and cellular longevity.

Mevastatin ameliorates sphingosine 1‐phosphate‐induced COX‐2/PGE2‐dependent cell migration via FoxO1 and CREB phosphorylation and translocation

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2015, British journal of pharmacology.

Heme oxygenase‐1 induction by rosiglitazone via PKC&agr;/AMPK&agr;/p38 MAPK&agr;/SIRT1/PPAR&ggr; pathway suppresses lipopolysaccharide‐mediated pulmonary inflammation

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2018, Biochemical pharmacology.

Sphingosine 1-Phosphate Induces Cyclooxygenase-2/Prostaglandin E2 Expression via PKCα-dependent Mitogen-Activated Protein Kinases and NF-κB Cascade in Human Cardiac Fibroblasts

L. Hsiao, Chuen-Mao Yang, Chien-Chung Yang, 2020, Frontiers in Pharmacology.

Sphingosine 1-Phosphate-Induced ICAM-1 Expression via NADPH Oxidase/ROS-Dependent NF-κB Cascade on Human Pulmonary Alveolar Epithelial Cells

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2016, Front. Pharmacol..

Sphingosine-1-Phosphate Mediates ICAM-1-Dependent Monocyte Adhesion through p38 MAPK and p42/p44 MAPK-Dependent Akt Activation

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2015, PloS one.

Sphingosine‐1‐Phosphate Mediates COX‐2 Expression and PGE2/IL‐6 Secretion via c‐Src‐Dependent AP‐1 Activation

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2015, Journal of cellular physiology.

Pharmacological andfunctional characterization ofbradykinin receptors incanine cultured tracheal epithelial cells

S. Pan, Chuen-Mao Yang, S. Luo, 1996 .

TNF- (cid:2) induces cytosolic phospholipase A 2 expression via Jak2/PDGFR-dependent Elk-1/p300 activation in human lung epithelial cells

L. Hsiao, Chuen-Mao Yang, I-Ta Lee, 2014 .

TNF-α induces matrix metalloproteinase-9-dependent soluble intercellular adhesion molecule-1 release via TRAF2-mediated MAPKs and NF-κB activation in osteoblast-like MC3T3-E1 cells

H. Hsieh, L. Hsiao, Chuen-Mao Yang, 2014, Journal of Biomedical Science.

Thrombin Induces EGF Receptor Expression and Cell Proliferation via a PKC(&dgr;)/c-Src–Dependent Pathway in Vascular Smooth Muscle Cells

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2009, Arteriosclerosis, thrombosis, and vascular biology.

PKC-delta/c-Src-mediated EGF receptor transactivation regulates thrombin-induced COX-2 expression and PGE(2) production in rat vascular smooth muscle cells.

H. Hsieh, Chuen-Mao Yang, Chi-Chin Sun, 2008, Biochimica et biophysica acta.

TNF‐α‐induced expression of cytosolic phospholipase A2 in human synovial fibroblast of rheumatoid arthritis

Chuen-Mao Yang, Chun Liu, 2007 .

Tumor necrosis factor-α-induced cyclooxygenase-2 expression in human tracheal smooth muscle cells : involvement of p42/p44 and p38 mitogen-activated protein kinases and nuclear factor-κB

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2004 .

Induction of cyclooxygenase-2 expression in human tracheal smooth muscle cells by interleukin-1beta: involvement of p42/p44 and p38 mitogen-activated protein kinases and nuclear factor-kappaB.

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2004, Journal of biomedical science.

Induction of cyclooxygenase-2 by lipopolysaccharide in canine tracheal smooth muscle cells: involvement of p42/p44 and p38 mitogen-activated protein kinases and nuclear factor-kappaB pathways.

L. Hsiao, Chuen-Mao Yang, S. Luo, 2003, Cellular signalling.

Interleukin-1β-induced cyclooxygenase-2 expression is mediated through activation of p42/44 and p38 MAPKS, and NF-κB pathways in canine tracheal smooth muscle cells

L. Hsiao, Chuen-Mao Yang, S. Luo, 2002 .

c-Src/Pyk2/EGFR/PI3K/Akt/CREB-activated pathway contributes to human cardiomyocyte hypertrophy: Role of COX-2 induction

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2015, Molecular and Cellular Endocrinology.

Adenosine triphosphate regulates NADPH oxidase activity leading to hydrogen peroxide production and COX-2/PGE2 expression in A549 cells.

Wan-Ling Wu, Chih‐Chung Lin, Chuen-Mao Yang, 2012, American journal of physiology. Lung cellular and molecular physiology.

Tumor Necrosis Factor-α-Induced C-C Motif Chemokine Ligand 20 Expression through TNF Receptor 1-Dependent Activation of EGFR/p38 MAPK and JNK1/2/FoxO1 or the NF-κB Pathway in Human Cardiac Fibroblasts

L. Hsiao, Chuen-Mao Yang, Chien-Chung Yang, 2022, International journal of molecular sciences.

TNF-α-Induced cPLA2 Expression via NADPH Oxidase/Reactive Oxygen Species-Dependent NF-κB Cascade on Human Pulmonary Alveolar Epithelial Cells

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2016, Front. Pharmacol..

Induction of cytosolic phospholipase A2 by lipopolysaccharide in canine tracheal smooth muscle cells: involvement of MAPKs and NF-kappaB pathways.

L. Hsiao, Chuen-Mao Yang, Chiang-Wen Lee, 2006, Cellular signalling.

Lysophosphatidylcholine induces cyclooxygenase-2-dependent IL-6 expression in human cardiac fibroblasts

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2018, Cellular and Molecular Life Sciences.

Transactivation of Src, PDGF receptor, and Akt is involved in IL‐1β‐induced ICAM‐1 expression in A549 cells

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2007, Journal of cellular physiology.

Induction of Heme Oxygenase-1 by 15d-Prostaglandin J2 Mediated via a ROS-Dependent Sp1 and AP-1 Cascade Suppresses Lipopolysaccharide-Triggered Interleukin-6 Expression in Mouse Brain Microvascular Endothelial Cells

L. Hsiao, Chuen-Mao Yang, Chien-Chung Yang, 2022, Antioxidants.

Carbon Monoxide Releasing Molecule-2-Upregulated ROS-Dependent Heme Oxygenase-1 Axis Suppresses Lipopolysaccharide-Induced Airway Inflammation

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2019, International journal of molecular sciences.

CO-Releasing Molecule-2 Induces Nrf2/ARE-Dependent Heme Oxygenase-1 Expression Suppressing TNF-α-Induced Pulmonary Inflammation

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2019, Journal of clinical medicine.

Carbon monoxide ameliorates Staphylococcus aureus-elicited COX-2/IL-6/MMP-9-dependent human aortic endothelial cell migration and inflammatory responses.

Chuen-Mao Yang, Wei-Ning Lin, R. Jiang, 2018, Immunology letters.

Arachidonic Acid Induces ARE/Nrf2-Dependent Heme Oxygenase-1 Transcription in Rat Brain Astrocytes

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2018, Molecular Neurobiology.

Heme Oxygenase-1 Induction by Carbon Monoxide Releasing Molecule-3 Suppresses Interleukin-1β-Mediated Neuroinflammation

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2017, Front. Mol. Neurosci..

The CO donor CORM‐2 inhibits LPS‐induced vascular cell adhesion molecule‐1 expression and leukocyte adhesion in human rheumatoid synovial fibroblasts

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2014, British journal of pharmacology.

Cigarette smoke extract upregulates heme oxygenase-1 via PKC/NADPH oxidase/ROS/PDGFR/PI3K/Akt pathway in mouse brain endothelial cells

L. Hsiao, Chuen-Mao Yang, Y. Kou, 2011, Journal of Neuroinflammation.

Cigarette smoke extract induces HO‐1 expression in mouse cerebral vascular endothelial cells: Involvement of c‐Src/NADPH oxidase/PDGFR/JAK2/STAT3 pathway

H. Hsieh, Chuen-Mao Yang, I-Ta Lee, 2010, Journal of cellular physiology.

Up-regulation of heme oxygenase-1 protects against cold injury-induced brain damage: a laboratory-based study.

Chuen-Mao Yang, Ruey-Horng Shih, Wei‐Hsuan Tung, 2010, Journal of neurotrauma.

Nox2/ROS-dependent human antigen R translocation contributes to TNF-α-induced SOCS-3 expression in human tracheal smooth muscle cells.

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2014, American journal of physiology. Lung cellular and molecular physiology.

Nox 2 / ROS-dependent human antigen R translocation contributes to TNF-- induced SOCS-3 expression in human tracheal smooth muscle cells

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2014 .

c-Src/Jak2/PDGFR/PKCδ-Dependent MMP-9 Induction Is Required for Thrombin-Stimulated Rat Brain Astrocytes Migration

H. Hsieh, Chih‐Chung Lin, L. Hsiao, 2014, Molecular Neurobiology.

Thrombin Induces COX-2 and PGE2 Expression via PAR1/PKCalpha/MAPK-Dependent NF-kappaB Activation in Human Tracheal Smooth Muscle Cells

L. Hsiao, Chuen-Mao Yang, Chien-Chung Yang, 2022, Mediators of inflammation.

Exercise modulates platelet-nasopharyngeal carcinoma cell aggregation and subsequent tissue factor and matrix metalloproteinase activities.

Chuen-Mao Yang, J. Wang, Yu-wen Chen, 2007, Journal of applied physiology.

Bradykinin-stimulated p42/p44 MAPK activation associated with cell proliferation in corneal keratocytes.

L. Hsiao, Chuen-Mao Yang, Ching-Yi Cheng, 2004, Cellular signalling.

Characterization of Bradykinin Receptors in Canine Cultured Corneal Epithelial Cells: Pharmacological and Functional Studies

L. Hsiao, Chuen-Mao Yang, C. Chien, 2002, Journal of Biomedical Science.

Characterization of bradykinin receptors in canine cultured corneal epithelial cells: pharmacological and functional studies.

L. Hsiao, Chuen-Mao Yang, C. Chien, 2002, Journal of biomedical science.

Pharmacological characterization of bradykinin receptors in canine cultured tracheal smooth muscle cells

Chuen-Mao Yang, S. Luo, H. Hsia, 1995, British journal of pharmacology.

Endothelin-1 induces VCAM-1 expression-mediated inflammation via receptor tyrosine kinases and Elk/p300 in human tracheal smooth muscle cells.

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2015, American journal of physiology. Lung cellular and molecular physiology.

Induction of Cyclooxygenase-2 Expression in Human Tracheal Smooth Muscle Cells by Interleukin-1β: Involvement of p42/p44 and p38 Mitogen-Activated Protein Kinases and Nuclear Factor-κB

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2004, Journal of Biomedical Science.

Carbon monoxide releasing molecule-2 protects against particulate matter-induced lung inflammation by inhibiting TLR2 and 4/ROS/NLRP3 inflammasome activation.

Pei-Ming Chu, Chuen-Mao Yang, Chiang-Wen Lee, 2019, Molecular immunology.

c-Src-dependent transactivation of PDGFR contributes to TNF-α-induced MMP-9 expression and functional impairment in osteoblasts.

Chuen-Mao Yang, I-Ta Lee, Pei-Ling Chi, 2014, Bone.

Lysophosphatidylcholine-induced mitochondrial fission contributes to collagen production in human cardiac fibroblasts[S]

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2019, Journal of Lipid Research.

Heme oxygenase 1 attenuates interleukin-1β-induced cytosolic phospholipase A2 expression via a decrease in NADPH oxidase/reactive oxygen species/activator protein 1 activation in rheumatoid arthritis synovial fibroblasts.

L. Hsiao, Chuen-Mao Yang, Yuh-Lien Chen, 2012, Arthritis and rheumatism.

Effect of phorbol ester on phosphoinositide hydrolysis and calcium mobilization in cultured canine tracheal smooth muscle cells

Chuen-Mao Yang, S. Luo, T. Sung, 1994, Naunyn-Schmiedeberg's Archives of Pharmacology.

ATP stimulates PGE(2)/cyclin D1-dependent VSMCs proliferation via STAT3 activation: role of PKCs-dependent NADPH oxidase/ROS generation.

Chih‐Chung Lin, Chuen-Mao Yang, J. Wang, 2013, Biochemical pharmacology.

IL‐1β induces urokinse‐plasminogen activator expression and cell migration through PKCα, JNK1/2, and NF‐κB in A549 cells

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2009, Journal of cellular physiology.

Calmodulin kinase II-dependent transactivation of PDGF receptors mediates astrocytic MMP-9 expression and cell motility induced by lipoteichoic acid

H. Hsieh, Chuen-Mao Yang, Hui-Hsin Wang, 2010, Journal of Neuroinflammation.

Thrombin Mediates Migration of Rat Brain Astrocytes via PLC, Ca2+, CaMKII, PKCα, and AP-1-Dependent Matrix Metalloproteinase-9 Expression

H. Hsieh, Chih‐Chung Lin, L. Hsiao, 2013, Molecular Neurobiology.

Tumour necrosis factor-α enhances bradykinin-induced signal transduction via activation of Ras/Raf/MEK/MAPK in canine tracheal smooth muscle cells

L. Hsiao, Chuen-Mao Yang, S. Luo, 2001 .

Role of NADPH oxidase/ROS in pro-inflammatory mediators-induced airway and pulmonary diseases.

Chuen-Mao Yang, I-Ta Lee, 2012, Biochemical pharmacology.

Resveratrol Attenuates Staphylococcus Aureus-Induced Monocyte Adhesion through Downregulating PDGFR/AP-1 Activation in Human Lung Epithelial Cells

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2018, International journal of molecular sciences.

TNF-α Mediates PKCδ/JNK1/2/c-Jun-Dependent Monocyte Adhesion via ICAM-1 Induction in Human Retinal Pigment Epithelial Cells

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2015, PloS one.

Resveratrol inhibits Staphylococcus aureus-induced TLR2/MyD88/NF-κB-dependent VCAM-1 expression in human lung epithelial cells.

Chih‐Chung Lin, Chuen-Mao Yang, R. Cho, 2014, Clinical science.

HO-1 Induction by CO-RM2 Attenuates TNF-α-Induced Cytosolic Phospholipase A2 Expression via Inhibition of PKCα-Dependent NADPH Oxidase/ROS and NF-κB

L. Hsiao, Chuen-Mao Yang, I-Ta Lee, 2014, Mediators of inflammation.

NADPH oxidase/ROS-dependent PYK2 activation is involved in TNF-α-induced matrix metalloproteinase-9 expression in rat heart-derived H9c2 cells.

L. Hsiao, Chuen-Mao Yang, I-Ta Lee, 2013, Toxicology and applied pharmacology.

c-Src-dependent MAPKs/AP-1 activation is involved in TNF-α-induced matrix metalloproteinase-9 expression in rat heart-derived H9c2 cells.

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2013, Biochemical pharmacology.

Astrocyte as the Modulator in Brain Inflammation and Neurodegenerative Disorders

H. Hsieh, Chuen-Mao Yang, 2016 .

Role of Redox Signaling in Neuroinflammation and Neurodegenerative Diseases

H. Hsieh, Chuen-Mao Yang, 2013, BioMed research international.

Galangin Inhibits LPS-Induced MMP-9 Expression via Suppressing Protein Kinase-Dependent AP-1 and FoxO1 Activation in Rat Brain Astrocytes

L. Hsiao, Chuen-Mao Yang, Chien-Chung Yang, 2020, Journal of inflammation research.

Galangin Inhibits Thrombin-Induced MMP-9 Expression in SK-N-SH Cells via Protein Kinase-Dependent NF-κB Phosphorylation

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2018, International journal of molecular sciences.

Pristimerin Inhibits MMP-9 Expression and Cell Migration Through Attenuating NOX/ROS-Dependent NF-κB Activation in Rat Brain Astrocytes Challenged with LPS

L. Hsiao, Chuen-Mao Yang, C. Kuo, 2020, Journal of inflammation research.

Sphingosine 1-phosphate induces EGFR expression via Akt/NF-kappaB and ERK/AP-1 pathways in rat vascular smooth muscle cells.

H. Hsieh, Chuen-Mao Yang, Cheng-Ying Wu, 2008, Journal of cellular biochemistry.

Mevastatin-Induced AP-1-Dependent HO-1 Expression Suppresses Vascular Cell Adhesion Molecule-1 Expression and Monocyte Adhesion on Human Pulmonary Alveolar Epithelial Cells Challenged with TNF-α

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2020, Biomolecules.

High Glucose Induces Reactive Oxygen Species-Dependent Matrix Metalloproteinase-9 Expression and Cell Migration in Brain Astrocytes

H. Hsieh, Chih‐Chung Lin, L. Hsiao, 2013, Molecular Neurobiology.

20-HETE inhibits the proliferation of vascular smooth muscle cells via transforming growth factor-β Published, JLR Papers in Press, October 4, 2007.

Chuen-Mao Yang, H. Ives, chan-Jung liang, 2008, Journal of Lipid Research.

Novel laminin 5 gamma 2-chain fragments potentiating the limbal epithelial cell outgrowth on amniotic membrane.

H. Hsieh, Chuen-Mao Yang, Ching-Yi Cheng, 2009, Investigative ophthalmology & visual science.

Regulation of 5-hydroxytryptamine-induced calcium mobilization by cAMP-elevating agents in cultured canine tracheal smooth muscle cells

L. Fan, Chuen-Mao Yang, C. Chiu, 1996, Pflügers Archiv - European Journal of Physiology.

Effects of CAMP elevating agents on carbachol-induced phosphoinositide hydrolysis and calcium mobilization in cultured canine tracheal smooth muscle cells

L. Fan, Chuen-Mao Yang, C. Chiu, 1996 .

P2Y2 receptor‐mediated proliferation of C6 glioma cells via activation of Ras/Raf/MEK/MAPK pathway

Chih‐Chung Lin, Chuen-Mao Yang, S. Luo, 2000, British journal of pharmacology.

Upregulation of COX-2/PGE2 by ET-1 Mediated Through Ca2+-Dependent Signals in Mouse Brain Microvascular Endothelial Cells

H. Hsieh, Chih‐Chung Lin, L. Hsiao, 2014, Molecular Neurobiology.

NADPH oxidase 2-derived reactive oxygen species signal contributes to bradykinin-induced matrix metalloproteinase-9 expression and cell migration in brain astrocytes

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2012, Cell Communication and Signaling.

Lipoteichoic acid-stimulated p42/p44 MAPK activation via Toll-like receptor 2 in tracheal smooth muscle cells.

Chuen-Mao Yang, Chiang-Wen Lee, C. Chien, 2004, American journal of physiology. Lung cellular and molecular physiology.

Calcium mobilization induced by endothelins and sarafotoxin in cultured canine tracheal smooth muscle cells

Chuen-Mao Yang, R. Ong, J. Hsieh, 1994, Naunyn-Schmiedeberg's Archives of Pharmacology.

TNF- (cid:68) enhances neutrophil adhesiveness: Induction of VCAM-1 via activation of Akt and CaM kinaseII and modifications of HAT and HDAC4 in human tracheal smooth muscle cells

W. Aird, Chih‐Chung Lin, Chuen-Mao Yang, 2008 .

Bradykinin B2 receptor-mediated proliferation via activation of the Ras/Raf/MEK/MAPK pathway in rat vascular smooth muscle cells.

L. Hsiao, Chuen-Mao Yang, C. Chien, 2003, Journal of biomedical science.

Photosensitizer Targeting: Mitochondrion-Targeted Photosensitizer Enhances Mitochondrial Reactive Oxygen Species and Mitochondrial Calcium-Mediated Apoptosis

T. Peng, Chuen-Mao Yang, M. Jou, 2005 .

ATP Mediates NADPH Oxidase/ROS Generation and COX-2/PGE2 Expression in A549 Cells: Role of P2 Receptor-Dependent STAT3 Activation

Wan-Ling Wu, Chih‐Chung Lin, L. Hsiao, 2013, PloS one.

NF-kappaB Signaling Pathways in Neurological Inflammation: A Mini Review

Chuen-Mao Yang, Chen-Yu Wang, Ruey-Horng Shih, 2015, Front. Mol. Neurosci..

BK-induced COX-2 expression via PKC-delta-dependent activation of p42/p44 MAPK and NF-kappaB in astrocytes.

P. Parker, H. Hsieh, Chuen-Mao Yang, 2007, Cellular signalling.

BK‐induced COX‐2 expression via PKC‐δ‐dependent activation of p42/p44 MAPK and NF‐κB in astrocytes

H. Hsieh, Chuen-Mao Yang, 2006 .

Interleukin‐1 Receptor Antagonist (IL‐1RA) Prevents Apoptosis in Ex Vivo Expansion of Human Limbal Epithelial Cells Cultivated on Human Amniotic Membrane

Chuen-Mao Yang, Ching-Yi Cheng, Chi-Chin Sun, 2006, Stem cells.

IL-1β Promotes Corneal Epithelial Cell Migration by Increasing MMP-9 Expression through NF-κB- and AP-1-Dependent Pathways

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2013, PloS one.

PI3-K/Akt/JNK/NF-κB is essential for MMP-9 expression and outgrowth in human limbal epithelial cells on intact amniotic membrane.

H. Hsieh, L. Hsiao, Chuen-Mao Yang, 2012, Stem cell research.

Role of matrix metalloproteinase-9 in ex vivo expansion of human limbal epithelial cells cultured on human amniotic membrane.

Chuen-Mao Yang, Ching-Yi Cheng, C. Chien, 2005, Investigative ophthalmology & visual science.

Inflammatory Signalings Involved in Airway and Pulmonary Diseases

Chuen-Mao Yang, I-Ta Lee, 2013, Mediators of inflammation.

Curcumin Nanoparticles Ameliorate ICAM-1 Expression in TNF-α-Treated Lung Epithelial Cells through p47 phox and MAPKs/AP-1 Pathways

Chun-ching Lin, Chuen-Mao Yang, Chiang-Wen Lee, 2013, PloS one.

Protective effects of (-)-epigallocatechin-3-gallate against TNF-α-induced lung inflammation via ROS-dependent ICAM-1 inhibition.

Chih‐Chung Lin, Chuen-Mao Yang, P. Hsieh, 2013, The Journal of nutritional biochemistry.

Enterovirus 71 induces COX-2 expression via MAPKs, NF-kappaB, and AP-1 in SK-N-SH cells: Role of PGE(2) in viral replication.

H. Hsieh, Chuen-Mao Yang, Wei‐Hsuan Tung, 2010, Cellular signalling.

Antimuscarinic action of liriodenine, isolated from Fissistigma glaucescens, in canine tracheal smooth muscle

C. H. Lin, C. Teng, Chuen-Mao Yang, 1994, British journal of pharmacology.

5‐Hydroxytryptamine receptor‐mediated phosphoinositide hydrolysis in canine cultured tracheal smooth muscle cells

Chuen-Mao Yang, C. Yang, R. Ong, 1994, British journal of pharmacology.

Activation and induction of cytosolic phospholipase A2 by TNF‐α mediated through Nox2, MAPKs, NF‐κB, and p300 in human tracheal smooth muscle cells

Chih‐Chung Lin, Chuen-Mao Yang, Chiang-Wen Lee, 2011, Journal of cellular physiology.

Activation and induction of cytosolic phospholipase A2 by IL‐1β in human tracheal smooth muscle cells: Role of MAPKs/p300 and NF‐κB

Chih‐Chung Lin, Chuen-Mao Yang, Chiang-Wen Lee, 2010, Journal of cellular biochemistry.

Involvement of MAPKs and NF-kappaB in tumor necrosis factor alpha-induced vascular cell adhesion molecule 1 expression in human rheumatoid arthritis synovial fibroblasts.

H. Hsieh, Chih‐Chung Lin, L. Hsiao, 2010, Arthritis and rheumatism.

IL-1 beta promotes A549 cell migration via MAPKs/AP-1- and NF-kappaB-dependent matrix metalloproteinase-9 expression.

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2009, Cellular signalling.

Involvement of MAPKs, NF-kappaB and p300 co-activator in IL-1beta-induced cytosolic phospholipase A2 expression in canine tracheal smooth muscle cells.

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2008, Toxicology and applied pharmacology.

Intracellular signalings underlying bradykinin-induced matrix metalloproteinase-9 expression in rat brain astrocyte-1.

H. Hsieh, Chuen-Mao Yang, M. Jou, 2004, Cellular signalling.

Intracellular signaling mechanisms underlying the expression of pro-inflammatory mediators in airway diseases.

H. Hsieh, Chuen-Mao Yang, Chiang-Wen Lee, 2005, Chang Gung medical journal.

Bradykinin B2 Receptor-Mediated Proliferation via Activation of the Ras/Raf/MEK/MAPK Pathway in Rat Vascular Smooth Muscle Cells

L. Hsiao, Chuen-Mao Yang, C. Chien, 2003, Journal of Biomedical Science.

Mitogenic effect of oxidized low‐density lipoprotein on vascular smooth muscle cells mediated by activation of Ras/Raf/MEK/MAPK pathway

S. Pan, Chih‐Chung Lin, L. Hsiao, 2001, British journal of pharmacology.

Lipopolysaccharide enhances bradykinin‐induced signal transduction via activation of Ras/Raf/MEK/MAPK in canine tracheal smooth muscle cells

Chien-Huang Lin, L. Hsiao, Chuen-Mao Yang, 2000, British journal of pharmacology.

ET‐1 induces COX‐2/PGE2 expression via an ETA/B/PKCδ/c‐Src/PI3K/Akt‐dependent pathway in murine osteoblast‐like MC3T3‐E1 cells

Chuen-Mao Yang, Ying-yi Li, 2012 .

ET-1 induces COX-2 / PGE 2 expression via an ET A / B / PKC / cSrc / PI 3 K / Akt-dependent pathway in murine osteoblast-like MC 3 T 3E 1 cells

Chuen-Mao Yang, Ying-yi Li, 2012 .

Bradykinin‐induced p42/p44 MAPK phosphorylation and cell proliferation via Src, EGF receptors, and PI3‐K/Akt in vascular smooth muscle cells

H. Hsieh, L. Hsiao, Chuen-Mao Yang, 2005, Journal of cellular physiology.

Lipopolysaccharide induces VCAM-1 expression and neutrophil adhesion to human tracheal smooth muscle cells: involvement of Src/EGFR/PI3-K/Akt pathway.

Chih‐Chung Lin, Chuen-Mao Yang, S. Luo, 2008, Toxicology and applied pharmacology.

Visualization of melatonin’s multiple mitochondrial levels of protection against mitochondrial Ca2+‐mediated permeability transition and beyond in rat brain astrocytes

C. Chiao, T. Peng, R. Reiter, 2010, Journal of pineal research.

Retraction of publication.

Chuen-Mao Yang, Y. Lau, Jin-Chung Chen, 1998, JPMA. The Journal of the Pakistan Medical Association.

TNF-α induces cytosolic phospholipase A2 expression via Jak2/PDGFR-dependent Elk-1/p300 activation in human lung epithelial cells.

L. Hsiao, Chuen-Mao Yang, I-Ta Lee, 2014, American journal of physiology. Lung cellular and molecular physiology.

Upregulation of COX-2/PGE2 by ET-1 Mediated Through Ca2+-Dependent Signals in Mouse Brain Microvascular Endothelial Cells

H. Hsieh, Chih‐Chung Lin, L. Hsiao, 2014, Molecular Neurobiology.

TNF-α Induces Cytosolic Phospholipase A2 Expression in Human Lung Epithelial Cells via JNK1/2- and p38 MAPK-Dependent AP-1 Activation

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2013, PloS one.

Up-regulation of COX-2/PGE2 by endothelin-1 via MAPK-dependent NF-κB pathway in mouse brain microvascular endothelial cells

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2013, Cell Communication and Signaling.

c-Src-dependent EGF receptor transactivation contributes to ET-1-induced COX-2 expression in brain microvascular endothelial cells

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2012, Journal of Neuroinflammation.

Mechanical Strain Induces Collagenase-3 (MMP-13) Expression in MC3T3-E1 Osteoblastic Cells*

Yu-Chen Huang, L. Hsiao, Chuen-Mao Yang, 2004, Journal of Biological Chemistry.

Sphingosine 1-Phosphate-Upregulated COX-2/PGE2 System Contributes to Human Cardiac Fibroblast Apoptosis: Involvement of MMP-9-Dependent Transactivation of EGFR Cascade

L. Hsiao, Chuen-Mao Yang, Chien-Chung Yang, 2022, Oxidative medicine and cellular longevity.

IL‐1β induces proMMP‐9 expression via c‐Src‐dependent PDGFR/PI3K/Akt/p300 cascade in rat brain astrocytes

C. Tseng, H. Hsieh, Chuen-Mao Yang, 2008, Journal of neurochemistry.

Endothelin‐1 enhances cell migration via matrix metalloproteinase‐9 up‐regulation in brain astrocytes

H. Hsieh, Chuen-Mao Yang, Cheng-Ying Wu, 2010, Journal of neurochemistry.

Japanese encephalitis virus induces matrix metalloproteinase‐9 in rat brain astrocytes via NF‐κB signalling dependent on MAPKs and reactive oxygen species

Wei-June Chen, H. Hsieh, Chuen-Mao Yang, 2010, British journal of pharmacology.

Induction of HO-1 by carbon monoxide releasing molecule-2 attenuates thrombin-induced COX-2 expression and hypertrophy in primary human cardiomyocytes.

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2015, Toxicology and applied pharmacology.

Involvement of FoxO1, Sp1, and Nrf2 in Upregulation of Negative Regulator of ROS by 15d-PGJ2 Attenuates H2O2-Induced IL-6 Expression in Rat Brain Astrocytes

L. Hsiao, Chuen-Mao Yang, Chien-Chung Yang, 2022, Neurotoxicity Research.

Cytosolic phospholipase A2 induction and prostaglandin E2 release by interleukin-1β via the myeloid differentiation factor 88-dependent pathway and cooperation of p300, Akt, and NF-κB activity in human rheumatoid arthritis synovial fibroblasts.

H. Hsieh, L. Hsiao, Chuen-Mao Yang, 2011, Arthritis and rheumatism.

TNF-α induces MMP-9 expression via activation of Src/EGFR, PDGFR/PI3K/Akt cascade and promotion of NF-κB/p300 binding in human tracheal smooth muscle cells

Chih‐Chung Lin, Chuen-Mao Yang, Chiang-Wen Lee, 2007 .

Role of TLR4/NADPH oxidase/ROS-activated p38 MAPK in VCAM-1 expression induced by lipopolysaccharide in human renal mesangial cells

Chih‐Chung Lin, Chuen-Mao Yang, I-Ta Lee, 2012, Cell Communication and Signaling.

NADPH Oxidase/ROS-Dependent VCAM-1 Induction on TNF-α-Challenged Human Cardiac Fibroblasts Enhances Monocyte Adhesion

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2016, Front. Pharmacol..

Activation of ROS/NF-kappaB and Ca2+/CaM kinase II are necessary for VCAM-1 induction in IL-1beta-treated human tracheal smooth muscle cells.

Chih‐Chung Lin, Chuen-Mao Yang, Chiang-Wen Lee, 2009, Toxicology and applied pharmacology.

CO Induces Nrf2-Dependent Heme Oxygenase-1 Transcription by Cooperating with Sp1 and c-Jun in Rat Brain Astrocytes

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2014, Molecular Neurobiology.

Cigarette smoke extract induces COX-2 expression via a PKCalpha/c-Src/EGFR, PDGFR/PI3K/Akt/NF-kappaB pathway and p300 in tracheal smooth muscle cells.

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2009, American journal of physiology. Lung cellular and molecular physiology.

Cardiovascular , Pulmonary and Renal Pathology Cooperation of TLR 2 with MyD 88 , PI 3 K , and Rac 1 in Lipoteichoic Acid – Induced cPLA 2 / COX-2 – Dependent Airway Inflammatory Responses

Chih‐Chung Lin, Chuen-Mao Yang, Chiang-Wen Lee, 2010 .

Bradykinin‐stimulated phosphoinositide metabolism in cultured canine tracheal smooth muscle cells

Chuen-Mao Yang, S. Luo, C. Yang, 1994, British journal of pharmacology.

Thrombin-stimulated cell proliferation mediated through activation of Ras/Raf/MEK/MAPK pathway in canine cultured tracheal smooth muscle cells.

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2002, Cellular signalling.

Tumor necrosis factor-alpha induces VCAM-1-mediated inflammation via c-Src-dependent transactivation of EGF receptors in human cardiac fibroblasts

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2015, Journal of Biomedical Science.

TNF-alpha induces MMP-9 expression via activation of Src/EGFR, PDGFR/PI3K/Akt cascade and promotion of NF-kappaB/p300 binding in human tracheal smooth muscle cells.

Chih‐Chung Lin, Chuen-Mao Yang, Chiang-Wen Lee, 2007, American journal of physiology. Lung cellular and molecular physiology.

Cigarette smoke extract induces COX-2 expression via a PKC / cSrc / EGFR , PDGFR / PI 3 K / Akt / NF-B pathway and p 300 in tracheal smooth muscle cells

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2009 .

TLR4‐dependent induction of vascular adhesion molecule‐1 in rheumatoid arthritis synovial fibroblasts: Roles of cytosolic phospholipase A2α/cyclooxygenase‐2

H. Hsieh, Chuen-Mao Yang, Cheng-Ying Wu, 2010, Journal of cellular physiology.

Nitric oxide production by endothelin‐1 enhances astrocytic migration via the tyrosine nitration of matrix metalloproteinase‐9

H. Hsieh, Chuen-Mao Yang, Hui-Hsin Wang, 2011, Journal of cellular physiology.

Muscarinic regulation of cytosolic free calcium in canine tracheal smooth muscle cells: Ca2+ requirement for phospholipase C activation

Chuen-Mao Yang, C. Yang, S. Chou, 1993, British journal of pharmacology.

Lysophosphatidylcholine induces cyclooxygenase-2-dependent IL-6 expression in human cardiac fibroblasts

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2018, Cellular and Molecular Life Sciences.

Induction of HO-1 by 5, 8-Dihydroxy-4′,7-Dimethoxyflavone via Activation of ROS/p38 MAPK/Nrf2 Attenuates Thrombin-Induced Connective Tissue Growth Factor Expression in Human Cardiac Fibroblasts

L. Hsiao, Chuen-Mao Yang, Chien-Chung Yang, 2020, Oxidative medicine and cellular longevity.

Lipopolysaccharide-Induced Matrix Metalloproteinase-9 Expression Associated with Cell Migration in Rat Brain Astrocytes

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2019, International journal of molecular sciences.

Warm-up exercise suppresses platelet-eosinophil/neutrophil aggregation and platelet-promoted release of eosinophil/neutrophil oxidant products enhanced by severe exercise in men

Chuen-Mao Yang, J. Wang, Hsiang Yen, 2006, Thrombosis and Haemostasis.

Cigarette smoke extract induces cytosolic phospholipase A2 expression via NADPH oxidase, MAPKs, AP-1, and NF-κB in human tracheal smooth muscle cells

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2009 .

Pharmacological and functional characterization of bradykinin receptors in canine cultured tracheal epithelial cells

S. Pan, Chuen-Mao Yang, S. Luo, 1996, British journal of pharmacology.

The carotenoid lutein enhances matrix metalloproteinase‐9 production and phagocytosis through intracellular ROS generation and ERK1/2, p38 MAPK, and RARβ activation in murine macrophages

Chuen-Mao Yang, Wen-Bin Wu, Chih‐Li Chen, 2013, Journal of leukocyte biology.

Cigarette smoke extract regulates cytosolic phospholipase A2 expression via NADPH oxidase/MAPKs/AP‐1 and p300 in human tracheal smooth muscle cells

Chih‐Chung Lin, Chuen-Mao Yang, I-Ta Lee, 2011, Journal of cellular biochemistry.

Japanese encephalitis virus induces matrix metalloproteinase-9 expression via a ROS/c-Src/PDGFR/PI3K/Akt/MAPKs-dependent AP-1 pathway in rat brain astrocytes

Wei-June Chen, Chih‐Chung Lin, L. Hsiao, 2012, Journal of Neuroinflammation.

Interleukin-1beta induces MMP-9 expression via p42/p44 MAPK, p38 MAPK, JNK, and nuclear factor-kappaB signaling pathways in human tracheal smooth muscle cells.

Chih‐Chung Lin, Chuen-Mao Yang, Chiang-Wen Lee, 2007, Journal of cellular physiology.

Endothelin‐ and Sarafotoxin‐Induced Phosphoinositide Hydrolysis in Cultured Canine Tracheal Smooth Muscle Cells

Chuen-Mao Yang, C. Yang, R. Ong, 1994, Journal of neurochemistry.

Regulation of cyclooxygenase‐2 and cytosolic phospholipase A2 gene expression by lipopolysaccharide through the RNA‐binding protein HuR: involvement of NADPH oxidase, reactive oxygen species and mitogen‐activated protein kinases

Chih‐Chung Lin, Chuen-Mao Yang, Hsin-Yi Cheng, 2011, British journal of pharmacology.

Tumour necrosis factor‐α‐ and interleukin‐1β‐stimulated cell proliferation through activation of mitogen‐activated protein kinase in canine tracheal smooth muscle cells

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2000 .

Up-regulation of ROS-Dependent Matrix Metalloproteinase-9 from High-Glucose-Challenged Astrocytes Contributes to the Neuronal Apoptosis

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2014, Molecular Neurobiology.

Multiple Factors from Bradykinin-Challenged Astrocytes Contribute to the Neuronal Apoptosis: Involvement of Astroglial ROS, MMP-9, and HO-1/CO System

H. Hsieh, Chih‐Chung Lin, L. Hsiao, 2013, Molecular Neurobiology.

BK‐induced cytosolic phospholipase A2 expression via sequential PKC‐δ, p42/p44 MAPK, and NF‐κB activation in rat brain astrocytes

P. Parker, H. Hsieh, Chuen-Mao Yang, 2006 .

Uncoupling of bradykinin‐induced phosphoinositide hydrolysis and Ca2+ mobilization by phorbol ester in canine cultured tracheal epithelial cells

S. Pan, Chuen-Mao Yang, S. Luo, 1998, British journal of pharmacology.

Inhibition of 5‐hydroxytryptamine‐induced phosphoinositide hydrolysis and Ca2+ mobilization in canine cultured tracheal smooth muscle cells by phorbol ester

Chuen-Mao Yang, C. Chiu, C. Yang, 1997, British journal of pharmacology.

Intracellular calcium in canine cultured tracheal smooth muscle cells is regulated by M3 muscarinic receptors

Chuen-Mao Yang, Y. Yo, Yen‐Yi Wang, 1993, British journal of pharmacology.

Transactivation of EGFR/PI3K/Akt involved in ATP‐induced inflammatory protein expression and cell motility

Chih‐Chung Lin, Chuen-Mao Yang, Hui-Hsin Wang, 2012, Journal of cellular physiology.

Cigarette smoke extract induces cytosolic phospholipase A2 expression via NADPH oxidase, MAPKs, AP-1, and NF-kappaB in human tracheal smooth muscle cells.

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2009, Free radical biology & medicine.

Neuroprotective Effects of Dehydroepiandrosterone Sulfate Through Inhibiting Expression of Matrix Metalloproteinase-9 from Bradykinin-Challenged Astroglia

Pei-Shan Liu, Tsong-Hai Lee, H. Hsieh, 2018, Molecular Neurobiology.

Involvement of p42/p44 MAPK, JNK, and NF-kappaB in IL-1beta-induced ICAM-1 expression in human pulmonary epithelial cells.

Chih‐Chung Lin, Chuen-Mao Yang, F. Lin, 2005, Journal of cellular physiology.

BK Induces cPLA2 Expression via an Autocrine Loop Involving COX-2-Derived PGE2 in Rat Brain Astrocytes

H. Hsieh, Chih‐Chung Lin, L. Hsiao, 2014, Molecular Neurobiology.

BK-induced cytosolic phospholipase A2 expression via sequential PKC-delta, p42/p44 MAPK, and NF-kappaB activation in rat brain astrocytes.

P. Parker, H. Hsieh, Chuen-Mao Yang, 2006, Journal of cellular physiology.

Bradykinin‐induced phosphoinositide hydrolysis and Ca2+ mobilization in canine cultured tracheal epithelial cells

S. Pan, Chuen-Mao Yang, S. Luo, 1999, British journal of pharmacology.

EV 71 induces COX-2 expression and PGE 2 synthesis through cSrc / EGFR / p 42 / p 44 MAPK-dependent CREB signaling in SKN-SH cells

H. Hsieh, Chuen-Mao Yang, I-Ta Lee, 2010 .

Lung inflammation caused by adenosine-5'-triphosphate is mediated via Ca2+/PKCs-dependent COX-2/PGE2 induction.

Wan-Ling Wu, Chih‐Chung Lin, L. Hsiao, 2013, The international journal of biochemistry & cell biology.

Muscarinic receptor subtypes coupled to generation of different second messengers in isolated tracheal smooth muscle cells

Chuen-Mao Yang, T. Sung, C. Yang, 1991, British journal of pharmacology.

Differential involvement of PKC-dependent MAPKs activation in lipopolysaccharide-induced AP-1 expression in human tracheal smooth muscle cells.

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2009, Cellular signalling.

Arachidonic Acid Induces ARE/Nrf2-Dependent Heme Oxygenase-1 Transcription in Rat Brain Astrocytes

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2017, Molecular Neurobiology.

The effect of cyclic AMP elevating agents on bradykinin‐ and carbachol‐induced signal transduction in canine cultured tracheal smooth muscle cells

Chuen-Mao Yang, S. Luo, C. Yang, 1994, British journal of pharmacology.

Semicarbazide‐sensitive Amine Oxidase from the Smooth Muscles of Dog Aorta and Trachea: Activation by the MAO‐A Inhibitor Clorgyline

Chuen-Mao Yang, P. Yu, C. Fang, 1992, The Journal of pharmacy and pharmacology.

Interleukin-1beta-induced cyclooxygenase-2 expression is mediated through activation of p42/44 and p38 MAPKS, and NF-kappaB pathways in canine tracheal smooth muscle cells.

L. Hsiao, Chuen-Mao Yang, S. Luo, 2002, Cellular signalling.

CO Induces Nrf2-Dependent Heme Oxygenase-1 Transcription by Cooperating with Sp1 and c-Jun in Rat Brain Astrocytes

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2015, Molecular Neurobiology.

c-Src/Jak2/PDGFR/PKCδ-Dependent MMP-9 Induction Is Required for Thrombin-Stimulated Rat Brain Astrocytes Migration

H. Hsieh, Chih‐Chung Lin, L. Hsiao, 2014, Molecular Neurobiology.

c‐Src‐dependent transactivation of EGFR mediates CORM‐2‐induced HO‐1 expression in human tracheal smooth muscle cells

H. Hsieh, Chih‐Chung Lin, L. Hsiao, 2015, Journal of cellular physiology.

Transforming growth factor-β1 induces matrix metalloproteinase-9 and cell migration in astrocytes: roles of ROS-dependent ERK- and JNK-NF-κB pathways

H. Hsieh, Chuen-Mao Yang, Wen-Bin Wu, 2010, Journal of Neuroinflammation.

Activation of mitogen-activated protein kinase by oxidized low-density lipoprotein in canine cultured vascular smooth muscle cells.

S. Pan, Chih‐Chung Lin, L. Hsiao, 2000, Cellular signalling.

TLR4‐dependent induction of vascular adhesion molecule‐1 in rheumatoid arthritis synovial fibroblasts: Roles of cytosolic phospholipase A2α/cyclooxygenase‐2

H. Hsieh, Chuen-Mao Yang, Cheng-Ying Wu, 2010, Journal of cellular physiology.

Cooperation of TLR2 with MyD88, PI3K, and Rac1 in lipoteichoic acid-induced cPLA2/COX-2-dependent airway inflammatory responses.

Chih‐Chung Lin, Chuen-Mao Yang, Chiang-Wen Lee, 2010, The American journal of pathology.

TNF-α Induces Cytosolic Phospholipase A2 Expression in Human Lung Epithelial Cells via JNK1/2- and p38 MAPK-Dependent AP-1 Activation

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2013, PloS one.

Reactive Oxygen Species-Dependent Activation of EGFR/Akt/p38 Mitogen-Activated Protein Kinase and JNK1/2/FoxO1 and AP-1 Pathways in Human Pulmonary Alveolar Epithelial Cells Leads to Up-Regulation of COX-2/PGE2 Induced by Silica Nanoparticles

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2023, Biomedicines.

BK Induces cPLA2 Expression via an Autocrine Loop Involving COX-2-Derived PGE2 in Rat Brain Astrocytes

H. Hsieh, Chih‐Chung Lin, L. Hsiao, 2014, Molecular Neurobiology.

TNF- (cid:2) induces cytosolic phospholipase A 2 expression via Jak2/PDGFR-dependent Elk-1/p300 activation in human lung epithelial cells

L. Hsiao, Chuen-Mao Yang, I-Ta Lee, 2014 .

Tumor necrosis factor-alpha-induced cyclooxygenase-2 expression in human tracheal smooth muscle cells: involvement of p42/p44 and p38 mitogen-activated protein kinases and nuclear factor-kappaB.

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2004, Cellular signalling.

CALL FOR PAPERS Biomarkers in Lung Diseases: from Pathogenesis to Prediction to New Therapies Endothelin-1 induces VCAM-1 expression-mediated inflammation via receptor tyrosine kinases and Elk/p300 in human tracheal smooth muscle cells

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2015 .

IL-1 beta promotes A549 cell migration via MAPKs/AP-1- and NF-kappaB-dependent matrix metalloproteinase-9 expression.

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2009, Cellular signalling.

W. Aird, Chih‐Chung Lin, Chuen-Mao Yang, 2008, Molecular Pharmacology.

Thrombin Induces EGF Receptor Expression and Cell Proliferation via a PKC(&dgr;)/c-Src–Dependent Pathway in Vascular Smooth Muscle Cells

H. Hsieh, Chih‐Chung Lin, Chuen-Mao Yang, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Bradykinin induces matrix metalloproteinase‐9 expression and cell migration through a PKC‐δ‐dependent ERK/Elk‐1 pathway in astrocytes

H. Hsieh, Chuen-Mao Yang, Cheng-Ying Wu, 2008, Glia.

Lipopolysaccharide induces ICAM-1 expression via a c-Src/NADPH oxidase/ROS-dependent NF-κB pathway in human pulmonary alveolar epithelial cells.

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2016, American journal of physiology. Lung cellular and molecular physiology.

P2y2 receptor-stimulated phosphoinositide hydrolysis and Ca2+ mobilization in tracheal epithelial cells

S. Pan, Chuen-Mao Yang, Wen Wu, 2000 .

P 2 Y 2 receptor-stimulated phosphoinositide hydrolysis and Ca 2 1 mobilization in tracheal epithelial cells

S. Pan, Chuen-Mao Yang, Y. Tsai, 2000 .

Pharmacological and functional characterization of bradykinin receptors in rat cultured vascular smooth muscle cells.

S. Pan, Chih‐Chung Lin, Chuen-Mao Yang, 1999, Cellular signalling.

Sphingosine‐1‐Phosphate Mediates COX‐2 Expression and PGE2/IL‐6 Secretion via c‐Src‐Dependent AP‐1 Activation

Chih‐Chung Lin, L. Hsiao, Chuen-Mao Yang, 2015, Journal of cellular physiology.

Mechanisms underlying the inhibitory effect of propofol on the contraction of canine airway smooth muscle.

S. Pan, Chih‐Chung Lin, Chuen-Mao Yang, 1999, Anesthesiology.