T. Ohashi

发表

Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 3. Evaluation of 5-amino-linked thiazolo[5,4-d]pyrimidine and thiazolo[5,4-b]pyridine derivatives.

Biching Sang, J. Yano, M. Hirose, 2012, Bioorganic & medicinal chemistry.

Ethyl 3-(1-Adamantyl)-2-diazo-3-oxopropanoate: Synthetic Use for the Preparation of Some Adamantane Derivatives

S. Eguchi, T. Ohashi, M. Itoh, 1993 .

Design, Synthesis, and Evaluation of 11C-Labeled 3-Acetyl-Indole Derivatives as a Novel Positron Emission Tomography Imaging Agent for Diacylglycerol Kinase Gamma (DGKγ) in Brain.

Ming-Rong Zhang, T. Ohashi, Tomoteru Yamasaki, 2021, Journal of medicinal chemistry.

Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 2. Synthesis and characterization of a novel imide-type prodrug for improving oral absorption.

M. Okaniwa, T. Miyazaki, T. Imada, 2012, Bioorganic & medicinal chemistry.

Synthesis and evaluation of hedgehog signaling inhibitor with novel core system.

S. Sasaki, T. Ohashi, Yuta Tanaka, 2015, Bioorganic & medicinal chemistry.

Design and synthesis of pyrrolo[3,2-d]pyrimidine human epidermal growth factor receptor 2 (HER2)/epidermal growth factor receptor (EGFR) dual inhibitors: exploration of novel back-pocket binders.

Toshimasa Tanaka, T. Ohashi, T. Ishikawa, 2012, Journal of medicinal chemistry.

Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors. 1. Exploration of [5,6]-fused bicyclic scaffolds.

H. Oki, Biching Sang, J. Yano, 2012, Journal of medicinal chemistry.

Discovery of pyrrolo[3,2-c]quinoline-4-one derivatives as novel hedgehog signaling inhibitors.

S. Sasaki, T. Ohashi, H. Tojo, 2012, Bioorganic & medicinal chemistry.

Synthetic Studies of Norzoanthamine. Preparation of the Diene-yne-diene Precursor of an ABC-ring Fragment

T. Ohashi, K. Suenaga, D. Uemura, 2005 .

Discovery of Brain-Penetrant Glucosylceramide Synthase Inhibitors with a Novel Pharmacophore.

H. Oki, T. Ohashi, Yuta Tanaka, 2022, Journal of medicinal chemistry.

Synergistic apoptotic effects in cancer cells by the combination of CLK and Bcl-2 family inhibitors

S. Sasaki, T. Miyazaki, T. Ohashi, 2020, PloS one.

CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor

Christopher S. Hughes, Jamie Rosner, S. McKinney, 2017, Nature Communications.

Chamber wall interactions with HBr/Cl2/O2 plasmas

V. M. Donnelly, T. Ohashi, A. Srivastava, 2015 .

Surface structure analysis of BaSi2(100) epitaxial film grown on Si(111) using CAICISS

T. Ohashi, M. Katayama, O. Kubo, 2015 .

CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor

Christopher S. Hughes, S. Aparicio, Jamie Rosner, 2017, Nature Communications.

Discovery of the investigational drug TAK-441, a pyrrolo[3,2-c]pyridine derivative, as a highly potent and orally active hedgehog signaling inhibitor: modification of the core skeleton for improved solubility.

S. Sasaki, T. Ohashi, Yuta Tanaka, 2012, Bioorganic & medicinal chemistry.

Perfect Composition Depth Profiling of Ionic Liquid Surfaces Using High-resolution RBS/ERDA

M. Lísal, T. Ohashi, K. Kimura, 2016, Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.

Design and synthesis of novel pyrimido[4,5-b]azepine derivatives as HER2/EGFR dual inhibitors.

Tomohiro Ohashi, Yoshikazu Ohta, Tomoyasu Ishikawa, 2013, Bioorganic & medicinal chemistry.