Yuta Tanaka

发表

Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 3. Evaluation of 5-amino-linked thiazolo[5,4-d]pyrimidine and thiazolo[5,4-b]pyridine derivatives.

Biching Sang, J. Yano, M. Hirose, 2012, Bioorganic & medicinal chemistry.

Discovery of potent Mcl-1/Bcl-xL dual inhibitors by using a hybridization strategy based on structural analysis of target proteins.

Yuta Tanaka, T. Kawamoto, T. Ishikawa, 2013, Journal of medicinal chemistry.

Discovery of novel serine palmitoyltransferase inhibitors as cancer therapeutic agents.

Yuta Tanaka, B. Saito, Kazunobu Aoyama, 2018, Bioorganic & medicinal chemistry.

Molecular dynamics study-guided identification of cyclic amine structures as novel hydrophobic tail components of hPPARγ agonists.

K. Matsuno, N. Matsuura, Yuta Tanaka, 2014, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of hedgehog signaling inhibitor with novel core system.

S. Sasaki, T. Ohashi, Yuta Tanaka, 2015, Bioorganic & medicinal chemistry.

A new brain‐penetrant glucosylceramide synthase inhibitor as potential Therapeutics for Gaucher disease

H. Oki, Yuta Tanaka, T. Onishi, 2021, Journal of neurochemistry.

Discovery of Novel Allosteric Inhibitors of Deoxyhypusine Synthase.

M. Klein, K. Ogawa, M. Okaniwa, 2020, Journal of medicinal chemistry.

Discovery of Brain-Penetrant Glucosylceramide Synthase Inhibitors with a Novel Pharmacophore.

H. Oki, T. Ohashi, Yuta Tanaka, 2022, Journal of medicinal chemistry.

Structural design and synthesis of arylalkynyl amide-type peroxisome proliferator-activated receptor γ (PPARγ)-selective antagonists based on the helix12-folding inhibition hypothesis.

M. Makishima, K. Matsuno, N. Matsuura, 2015, European journal of medicinal chemistry.

New Series of Potent Allosteric Inhibitors of Deoxyhypusine Synthase

M. Klein, M. Okaniwa, Yuta Tanaka, 2020, ACS medicinal chemistry letters.

Discovery of the investigational drug TAK-441, a pyrrolo[3,2-c]pyridine derivative, as a highly potent and orally active hedgehog signaling inhibitor: modification of the core skeleton for improved solubility.

S. Sasaki, T. Ohashi, Yuta Tanaka, 2012, Bioorganic & medicinal chemistry.

Discovery of the investigational drug TAK-441, a pyrrolo[3,2-c]pyridine derivative, as a highly potent and orally active hedgehog signaling inhibitor: modification of the core skeleton for improved solubility.

S. Sasaki, T. Ohashi, Yuta Tanaka, 2012, Bioorganic & medicinal chemistry.