Sei Yoshida

发表

Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 3. Evaluation of 5-amino-linked thiazolo[5,4-d]pyrimidine and thiazolo[5,4-b]pyridine derivatives.

Biching Sang, J. Yano, M. Hirose, 2012, Bioorganic & medicinal chemistry.

Role of Ragulator in the Regulation of Mechanistic Target of Rapamycin Signaling in Podocytes and Glomerular Function.

K. Inoki, S. Nada, M. Okada, 2016, Journal of the American Society of Nephrology : JASN.

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice.

M. Hall, K. Inoki, D. Kwiatkowski, 2011, The Journal of clinical investigation.

Novel HER2 selective tyrosine kinase inhibitor, TAK‐165, inhibits bladder, kidney and androgen‐independent prostate cancer in vitro and in vivo

Mikio Namiki, Atsushi Mizokami, Sei Yoshida, 2006, International journal of urology : official journal of the Japanese Urological Association.

Design and synthesis of potent inhibitor of apoptosis (IAP) proteins antagonists bearing an octahydropyrrolo[1,2-a]pyrazine scaffold as a novel proline mimetic.

T. Kojima, M. Yabuki, Sei Yoshida, 2013, Journal of medicinal chemistry.

Antitumor activity of the selective pan-RAF inhibitor TAK-632 in BRAF inhibitor-resistant melanoma.

Tomoyasu Ishikawa, Akito Nakamura, Katherine Galvin, 2013, Cancer research.

Antitumor Activity and Pharmacodynamic Biomarkers of a Novel and Orally Available Small-Molecule Antagonist of Inhibitor of Apoptosis Proteins

M. Yabuki, Sei Yoshida, T. Ishikawa, 2012, Molecular Cancer Therapeutics.

Shigella deliver an effector protein to trigger host microtubule destabilization, which promotes Rac1 activity and efficient bacterial internalization

C. Sasakawa, E. Katayama, Sei Yoshida, 2002, The EMBO journal.

Coordination of the Rab5 Cycle on Macropinosomes

J. Swanson, Sei Yoshida, S. Straight, 2011, Traffic.

Coordination of the Rab 5 Cycle on Macropinosomes

J. Swanson, Sei Yoshida, S. Straight, 2011 .

CXCL12‐induced macropinocytosis modulates two distinct pathways to activate mTORC1 in macrophages

J. Swanson, Sei Yoshida, Regina Pacitto, 2017, Journal of leukocyte biology.

Capecitabine Regulates HSP90AB1 Expression and Induces Apoptosis via Akt/SMARCC1/AP-1/ROS Axis in T Cells

Sei Yoshida, Tao Liu, Hong Zheng, 2022, Oxidative medicine and cellular longevity.

Complementary DNA Microarray Analysis in Acute Lung Injury Induced by Lipopolysaccharide and Diesel Exhaust Particles

T. Yoshikawa, Sei Yoshida, K. Takeda, 2004, Experimental biology and medicine.

Lung expression of cytochrome P450 1A1 as a possible biomarker of exposure to diesel exhaust particles

T. Yoshikawa, Sei Yoshida, K. Takeda, 2002, Archives of Toxicology.

Circular dorsal ruffles disturb the growth factor-induced PI3K-AKT pathway in hepatocellular carcinoma Hep3B cells

Sei Yoshida, Yujie Liu, Zhongyang Shen, 2022, Cell communication and signaling : CCS.

Endoplasmic reticulum-associated degradation is required for nephrin maturation and kidney glomerular filtration function.

J. Hodgin, M. Bitzer, E. Otto, 2021, The Journal of clinical investigation.

Identification of a new class of potent Cdc7 inhibitors designed by putative pharmacophore model: Synthesis and biological evaluation of 2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-ones.

T. Miyazaki, Sei Yoshida, T. Ishikawa, 2017, Bioorganic & medicinal chemistry.

Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 2. Synthesis and characterization of a novel imide-type prodrug for improving oral absorption.

M. Okaniwa, T. Miyazaki, T. Imada, 2012, Bioorganic & medicinal chemistry.

Identification of Circular Dorsal Ruffles as Signal Platforms for the AKT pathways in Glomerular Podocytes

K. Inoki, Sei Yoshida, M. Torres, 2022, bioRxiv.

Macropinosomes as units of signal transduction

J. Swanson, Sei Yoshida, 2018, Philosophical Transactions of the Royal Society B.

Preclinical Safety Evaluation of Intraperitoneally Administered Cu-Conjugated Anti-EGFR Antibody NCAB001 for the Early Diagnosis of Pancreatic Cancer Using PET

A. Waki, Sei Yoshida, M. Ueno, 2022, Pharmaceutics.

Reinforcement of antitumor effect of micelles containing anticancer drugs by binding of an anti-tissue factor antibody without direct cytocidal effects.

Sei Yoshida, Y. Matsumura, M. Yasunaga, 2020, Journal of controlled release : official journal of the Controlled Release Society.

The Journal of Experimental Medicine CORRESPONDENCE

A. Abe, Sei Yoshida, S. Koyasu, 2005 .

Dorsal ruffles enhance activation of Akt by growth factors

J. Swanson, Sei Yoshida, L. Kotula, 2018, Journal of Cell Science.

Sequential signaling in plasma-membrane domains during macropinosome formation in macrophages

J. Swanson, A. Hoppe, Sei Yoshida, 2009, Journal of Cell Science.

Microtubule-Severing Activity of Shigella Is Pivotal for Intercellular Spreading

C. Sasakawa, A. Abe, E. Katayama, 2006, Science.

Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors. 1. Exploration of [5,6]-fused bicyclic scaffolds.

H. Oki, Biching Sang, J. Yano, 2012, Journal of medicinal chemistry.

Exploiting host microtubule dynamics: a new aspect of bacterial invasion.

C. Sasakawa, Sei Yoshida, 2003, Trends in microbiology.

Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes

Simon Tavaré, Masashi Narita, Shamith A. Samarajiwa, 2011, Science.

Emerging role of autophagy in kidney function, diseases and aging

K. Inoki, Z. Dong, C. Edelstein, 2012, Autophagy.

Differential signaling during macropinocytosis in response to M-CSF and PMA in macrophages

Joel A. Swanson, Olivia Alge, J. Swanson, 2015, Front. Physiol..

Aminopeptidase N regulated by zinc in human prostate participates in tumor cell invasion

M. Tatematsu, Sei Yoshida, S. Usui, 2001, International journal of cancer.

Design, synthesis, and biological activities of novel hexahydropyrazino[1,2-a]indole derivatives as potent inhibitors of apoptosis (IAP) proteins antagonists with improved membrane permeability across MDR1 expressing cells.

M. Yabuki, Sei Yoshida, T. Ishikawa, 2013, Bioorganic & medicinal chemistry.

Design, stereoselective synthesis, and biological evaluation of novel tri-cyclic compounds as inhibitor of apoptosis proteins (IAP) antagonists.

C. Mol, M. Yabuki, Sei Yoshida, 2013, Bioorganic & medicinal chemistry.

Increased phosphorylation of Akt in triple‐negative breast cancers

Sei Yoshida, Y. Ohta, Y. Tokuda, 2007, Cancer science.

T-3256336, a novel and orally available small molecule IAP antagonist, induced tumor cell death via induction of systemic TNF alpha production.

M. Yabuki, Sei Yoshida, T. Ishikawa, 2016, Biochemical and biophysical research communications.

Capecitabine Can Induce T Cell Apoptosis: A Potential Immunosuppressive Agent With Anti-Cancer Effect

Sei Yoshida, Lei Cao, Shuang Yang, 2021, Frontiers in Immunology.

HIF-1α/FOXO1 axis regulated autophagy is protective for β cell survival under hypoxia in human islets.

Sei Yoshida, Lanqiu Zhang, Yaojuan Liu, 2022, Biochimica et biophysica acta. Molecular basis of disease.

Enteropathogenic Escherichia coli activates the RhoA signaling pathway via the stimulation of GEF‐H1

C. Sasakawa, A. Abe, Sei Yoshida, 2004, The EMBO journal.

An inhibitor of apoptosis protein antagonist T-3256336 potentiates the antitumor efficacy of the Nedd8-activating enzyme inhibitor pevonedistat (TAK-924/MLN4924).

Peter G. Smith, M. Yabuki, Sei Yoshida, 2016, Biochemical and biophysical research communications.

Discovery of a selective kinase inhibitor (TAK-632) targeting pan-RAF inhibition: design, synthesis, and biological evaluation of C-7-substituted 1,3-benzothiazole derivatives.

Tomoyasu Ishikawa, Akito Nakamura, Terufumi Takagi, 2013, Journal of medicinal chemistry.

Redox Regulates Mammalian Target of Rapamycin Complex 1 (mTORC1) Activity by Modulating the TSC1/TSC2-Rheb GTPase Pathway*

K. Inoki, Tsukasa Suzuki, K. Guan, 2011, The Journal of Biological Chemistry.

2-Aminomethylthieno[3,2-d]pyrimidin-4(3H)-ones bearing 3-methylpyrazole hinge binding moiety: Highly potent, selective, and time-dependent inhibitors of Cdc7 kinase.

T. Miyazaki, Sei Yoshida, Misaki Homma, 2017, Bioorganic & medicinal chemistry.

Growth factor signaling to mTORC1 by amino acid–laden macropinosomes

K. Inoki, J. Swanson, Sei Yoshida, 2015, The Journal of cell biology.

Loss of PTEN promotes formation of signaling-capable clathrin-coated pits

Kenneth K. Y. Ho, S. Merajver, J. Swanson, 2017, Journal of Cell Science.

Metronomic capecitabine inhibits liver transplant rejection in rats by triggering recipients’ T cell ferroptosis

Sei Yoshida, Lei Cao, Tao Liu, 2023, World journal of gastroenterology.

Macropinocytosis, mTORC1 and cellular growth control

K. Inoki, J. Swanson, Sei Yoshida, 2017, Cellular and Molecular Life Sciences.

Translational nanomedicine potentiates immunotherapy in sarcoma by normalizing the microenvironment.

S. Akinaga, Sei Yoshida, Myrofora Panagi, 2022, Journal of controlled release : official journal of the Controlled Release Society.

Agent prophylactique/thérapeutique contre le cancer à expression de her2

Sei Yoshida, K. Yoshimura, Toshiyuki Fujioka, 2006 .

Use of combination treatment with the investigational RAF kinase inhibitor MLN2480 and the investigational MEK kinase inhibitor TAK-733 on the growth of BRAF-mutant and RAS-mutant preclinical models of melanoma and CRC.

J. Mettetal, P. Vincent, Julie Zhang, 2013 .

Metronomic capecitabine with rapamycin exerts an immunosuppressive effect by inducing ferroptosis of CD4+ T cells after liver transplantation in rat.

Sei Yoshida, Lei Cao, Tao Chen, 2023, International immunopharmacology.

Identification of circular dorsal ruffles as signal platforms for the AKT pathway in glomerular podocytes

K. Inoki, Sei Yoshida, M. Torres, 2023, Journal of cellular physiology.

Bordetella evades the host immune system by inducing IL-10 through a type III effector, BopN

A. Abe, Sei Yoshida, S. Koyasu, 2009, The Journal of experimental medicine.

Characterization and Stabilization of a New 64Cu-Labeled Anti-EGFR Antibody NCAB001 for the Early Detection of Pancreatic Cancer with Positron Emission Tomography

A. Waki, T. Higashi, Sei Yoshida, 2021, Pharmaceutics.

Identification of circular dorsal ruffles as signal platforms for the AKT pathway in glomerular podocytes

K. Inoki, Sei Yoshida, M. Torres, 2023, Journal of cellular physiology.