K. Seldeen

发表

Multivalent binding and facilitated diffusion account for the formation of the Grb2-Sos1 signaling complex in a cooperative manner.

Amjad Farooq, Caleb B. McDonald, Jordan E Balke, 2012, Biochemistry.

Assembly of the Sos1-Grb2-Gab1 ternary signaling complex is under allosteric control.

Amjad Farooq, Caleb B. McDonald, V. Bhat, 2010, Archives of biochemistry and biophysics.

pH modulates the binding of early growth response protein 1 transcription factor to DNA

Caleb B. McDonald, V. Bhat, David C. Mikles, 2013, The FEBS journal.

Energetic coupling along an allosteric communication channel drives the binding of Jun‐Fos heterodimeric transcription factor to DNA

Caleb B. McDonald, V. Bhat, David C. Mikles, 2011, The FEBS journal.

Interactions of TRF2 with model telomeric ends.

S. Lindsay, K. Seldeen, Hongda Wang, 2007, Biochemical and biophysical research communications.

AGS and NIA Bench‐to Bedside Conference Summary: Osteoporosis and Soft Tissue (Muscle and Fat) Disorders

D. Kiel, D. Houston, R. Fielding, 2019, Journal of the American Geriatrics Society.

High Intensity Interval Training Improves Physical Performance and Frailty in Aged Mice

K. Seldeen, B. Troen, K. Personius, 2018, The journals of gerontology. Series A, Biological sciences and medical sciences.

Mouse Models of Frailty: an Emerging Field

K. Seldeen, B. Troen, M. Pang, 2015, Current Osteoporosis Reports.

BIOPHYSICAL ANALYSIS OF THE AP1-DNA INTERACTION

K. Seldeen, 2009 .

SRT2183 and SRT1720, but not Resveratrol, Inhibit Osteoclast Formation and Resorption in the Presence or Absence of Sirt1

K. Seldeen, B. Troen, R. Thiyagarajan, 2020, Journal of bone research.

Methamphetamine Induces Apoptosis of Microglia via the Intrinsic Mitochondrial-Dependent Pathway

K. Seldeen, A. Sharikova, A. Khmaladze, 2018, Journal of Neuroimmune Pharmacology.

A mouse model of vitamin D insufficiency: is there a relationship between 25(OH) vitamin D levels and obesity?

K. Seldeen, B. Troen, P. Yu, 2017, Nutrition & Metabolism.

Pinpointing a Role for Vitamin D in Frailty: A Time for Animal Models?

K. Seldeen, B. Troen, 2021, Advances in geriatric medicine and research.

Vitamin D Insufficiency Reduces Grip Strength, Grip Endurance and Increases Frailty in Aged C57Bl/6J Mice

K. Seldeen, B. Troen, R. Thiyagarajan, 2020, Nutrients.

Neuropeptide Y Y2 antagonist treated ovariectomized mice exhibit greater bone mineral density

C. Wahlestedt, L. Suva, S. Brothers, 2017, Neuropeptides.

Myeloid-Derived Suppressor Cells at the Intersection of Inflammaging and Bone Fragility

K. Seldeen, B. Troen, K. Kirkwood, 2018, Immunological investigations.

AP‐1 and Mitf interact with NFATc1 to stimulate cathepsin K promoter activity in osteoclast precursors

K. Seldeen, B. Troen, M. Pang, 2019, Journal of cellular biochemistry.

DNA plasticity is a key determinant of the energetics of binding of Jun-Fos heterodimeric transcription factor to genetic variants of TGACGTCA motif.

Caleb B. McDonald, V. Bhat, Brian J. Deegan, 2009, Biochemistry.

Thermodynamic analysis of the heterodimerization of leucine zippers of Jun and Fos transcription factors.

Caleb B. McDonald, Brian J. Deegan, K. Seldeen, 2008, Biochemical and biophysical research communications.

Tristetraprolin limits age-related expansion of myeloid-derived suppressor cells

P. Blackshear, K. Seldeen, S. Abrams, 2022, Frontiers in Immunology.

Basic nutritional investigationShort-term nicotinamide riboside treatment improves muscle quality and function in mice and increases cellular energetics and differentiating capacity of myogenic progenitors.

S. Andreadis, K. Seldeen, B. Troen, 2021, Nutrition.

Inhibition of glutaminolysis restores mitochondrial function in senescent stem cells

S. Andreadis, K. Seldeen, B. Troen, 2022, Cell reports.

Binding of the cSH3 domain of Grb2 adaptor to two distinct RXXK motifs within Gab1 docker employs differential mechanisms

Caleb B. McDonald, V. Bhat, Brian J. Deegan, 2011, Journal of molecular recognition : JMR.

Heat-induced fibrillation of BclXL apoptotic repressor.

I. Lednev, Caleb B. McDonald, V. Bhat, 2013, Biophysical chemistry.

Acidic pH promotes oligomerization and membrane insertion of the BclXL apoptotic repressor.

I. Lednev, Caleb B. McDonald, V. Bhat, 2012, Archives of biochemistry and biophysics.

Ligand binding and membrane insertion compete with oligomerization of the BclXL apoptotic repressor.

Caleb B. McDonald, V. Bhat, David C. Mikles, 2012, Journal of molecular biology.

Structural landscape of the proline-rich domain of Sos1 nucleotide exchange factor.

I. Lednev, Caleb B. McDonald, V. Bhat, 2013, Biophysical chemistry.

Dissecting the role of leucine zippers in the binding of bZIP domains of Jun transcription factor to DNA.

Caleb B. McDonald, V. Bhat, Brian J. Deegan, 2010, Biochemical and biophysical research communications.

Single nucleotide variants of the TGACTCA motif modulate energetics and orientation of binding of the Jun-Fos heterodimeric transcription factor.

Caleb B. McDonald, Brian J. Deegan, K. Seldeen, 2009, Biochemistry.

Evidence that the bZIP domains of the Jun transcription factor bind to DNA as monomers prior to folding and homodimerization.

Caleb B. McDonald, Brian J. Deegan, K. Seldeen, 2008, Archives of biochemistry and biophysics.

Coupling of folding and DNA-binding in the bZIP domains of Jun-Fos heterodimeric transcription factor.

Caleb B. McDonald, Brian J. Deegan, K. Seldeen, 2008, Archives of biochemistry and biophysics.

Allostery mediates ligand binding to Grb2 adaptor in a mutually exclusive manner

Caleb B. McDonald, V. Bhat, David C. Mikles, 2013, Journal of molecular recognition : JMR.

Bivalent binding drives the formation of the Grb2–Gab1 signaling complex in a noncooperative manner

Caleb B. McDonald, V. Bhat, David C. Mikles, 2012, The FEBS journal.

SH3 domains of Grb2 adaptor bind to PXpsiPXR motifs within the Sos1 nucleotide exchange factor in a discriminate manner.

Caleb B. McDonald, Brian J. Deegan, K. Seldeen, 2009, Biochemistry.

Structural basis of the differential binding of the SH3 domains of Grb2 adaptor to the guanine nucleotide exchange factor Sos1.

Caleb B. McDonald, Brian J. Deegan, K. Seldeen, 2008, Archives of biochemistry and biophysics.

Grb2 adaptor undergoes conformational change upon dimerization.

Marc S. Lewis, Caleb B. McDonald, Brian J. Deegan, 2008, Archives of biochemistry and biophysics.

Biophysical basis of the binding of WWOX tumor suppressor to WBP1 and WBP2 adaptors.

R. Aqeilan, Z. Nawaz, M. Sudol, 2012, Journal of molecular biology.

Biophysical analysis of binding of WW domains of the YAP2 transcriptional regulator to PPXY motifs within WBP1 and WBP2 adaptors.

Z. Nawaz, M. Sudol, L. Buffa, 2011, Biochemistry.

Absence of complement factor H reduces physical performance in C57BL6 mice.

J. Alexander, R. Quigg, K. Seldeen, 2020, Immunobiology.

High intensity interval training improves physical performance in aged female mice: A comparison of mouse frailty assessment tools

K. Seldeen, B. Troen, R. Thiyagarajan, 2019, Mechanisms of Ageing and Development.

Vitamin D: A Regulator of Metabolism and Inflammation

K. Seldeen, E. Cherniack, B. Troen, 2014 .

Ameliorating the hallmarks of cellular senescence in skeletal muscle myogenic progenitors in vitro and in vivo

Jianmin Wang, Song Liu, S. Andreadis, 2021, Science advances.

Absence of complement factor H alters bone architecture and dynamics.

J. Alexander, R. Quigg, K. Seldeen, 2018, Immunobiology.

Genetic variations within the ERE motif modulate plasticity and energetics of binding of DNA to the ERα nuclear receptor.

Caleb B. McDonald, V. Bhat, Brian J. Deegan, 2011, Archives of biochemistry and biophysics.

Binding of the ER R Nuclear Receptor to DNA Is Coupled to Proton Uptake †

Caleb B. McDonald, V. Bhat, Brian J. Deegan, 2010 .

Methionine adenosyltransferase2A inhibition restores metabolism to improve regenerative capacity and strength of aged skeletal muscle

S. Udin, S. Andreadis, K. Seldeen, 2023, Nature Communications.

Methamphetamine Induces Apoptosis of Microglia via the Intrinsic Mitochondrial-Dependent Pathway

K. Seldeen, A. Sharikova, A. Khmaladze, 2018, Journal of Neuroimmune Pharmacology.

Detection of bulky DNA lesions: DDB2 at the interface of chromatin and DNA repair in eukaryotes

K. Seldeen, Ling Zhang, Feng Gong, 2010, IUBMB life.

Structural and thermodynamic consequences of the replacement of zinc with environmental metals on estrogen receptor α–DNA interactions

Caleb B. McDonald, V. Bhat, Brian J. Deegan, 2011, Journal of molecular recognition : JMR.

Chronic vitamin D insufficiency impairs physical performance in C57BL/6J mice

K. Seldeen, B. Troen, J. Bard, 2018, Aging.

Ligand binding and membrane insertion compete with oligomerization of the BclXL apoptotic repressor.

Caleb B. McDonald, V. Bhat, David C. Mikles, 2012, Journal of molecular biology.

Proline restores mitochondrial function and reverses aging hallmarks in senescent cells

S. Andreadis, K. Seldeen, P. Lei, 2024, Cell Reports.

Biophysical analysis of binding of WW domains of the YAP2 transcriptional regulator to PPXY motifs within WBP1 and WBP2 adaptors.

Z. Nawaz, M. Sudol, L. Buffa, 2011, Biochemistry.

Biophysical basis of the binding of WWOX tumor suppressor to WBP1 and WBP2 adaptors.

R. Aqeilan, Z. Nawaz, M. Sudol, 2012, Journal of molecular biology.