B. Hansen

发表

In Situ Phosphorylation of Akt and ERK1/2 in Rat Mammary Gland, Colon, and Liver Following Treatment with Human Insulin and IGF-1

H. Hvid, J. Fels, R. K. Kirk, 2011, Toxicologic pathology.

Insulin aspart: a novel rapid-acting human insulin analogue.

S. Gammeltoft, B. Hansen, A. Lindholm, 1999, Expert opinion on investigational drugs.

Akt 2 influences glycogen synthase activity in human skeletal muscle through regulation of NH 2-terminal ( sites 2 2 a ) phosphorylation

P. Poulsen, A. Vaag, H. Beck-Nielsen, 2013 .

Akt2 influences glycogen synthase activity in human skeletal muscle through regulation of NH₂-terminal (sites 2 + 2a) phosphorylation.

P. Poulsen, A. Vaag, H. Beck-Nielsen, 2013, American journal of physiology. Endocrinology and metabolism.

No limiting role for glycogenin in determining maximal attainable glycogen levels in rat skeletal muscle.

W. Derave, B. Hansen, E. Richter, 2000, American journal of physiology. Endocrinology and metabolism.

Effects of glucose and insulin on development of impaired insulin action in muscle.

B. Hansen, E. Richter, T. Ploug, 1992, The American journal of physiology.

Insulin Signaling in Human Skeletal Muscle: Time Course and Effect of Exercise

B. Hansen, J. Wojtaszewski, E. Richter, 1997, Diabetes.

Insulin signaling and insulin sensitivity after exercise in human skeletal muscle.

B. Hansen, J. Markuns, L. Goodyear, 2000, Diabetes.

Increased phosphorylation of skeletal muscle glycogen synthase at NH2-terminal sites during physiological hyperinsulinemia in type 2 diabetes.

D. Hardie, K. Højlund, H. Beck-Nielsen, 2003, Diabetes.

Mechanisms limiting glycogen storage in muscle during prolonged insulin stimulation.

B. Hansen, E. Richter, S. Hansen, 1988, The American journal of physiology.

Wortmannin inhibits both insulin- and contraction-stimulated glucose uptake and transport in rat skeletal muscle.

B. Ursø, B. Hansen, J. Wojtaszewski, 1996, Journal of applied physiology.

Treatment with Insulin Analog X10 and IGF-1 Increases Growth of Colon Cancer Allografts

H. Hvid, J. Fels, B. Hansen, 2013, PloS one.

A framework for the in vitro evaluation of cancer-relevant molecular characteristics and mitogenic potency of insulin analogues

A. Renehan, D. Roberts, B. Hansen, 2015, Carcinogenesis.

Systematic Evaluation of the Metabolic to Mitogenic Potency Ratio for B10-Substituted Insulin Analogues

B. Hansen, E. Nishimura, C. Stidsen, 2012, PloS one.

Molecular Characterisation of Long-Acting Insulin Analogues in Comparison with Human Insulin, IGF-1 and Insulin X10

B. Hansen, C. Stidsen, R. Slaaby, 2012, PloS one.

Insulin therapy in diabetes and cancer risk: Current understanding and implications for future study

S. Gough, J. Tuomilehto, B. Hansen, 2011, Advances in therapy.

Insulin X10 revisited: a super-mitogenic insulin analogue

B. Hansen, D. Russell-Jones, P. Kurtzhals, 2011, Diabetologia.

AMP kinase activation ameliorates insulin resistance induced by free fatty acids in rat skeletal muscle.

B. Hansen, G. S. Olsen, 2002, American journal of physiology. Endocrinology and metabolism.

Increased insulin receptor binding and increased IGF-1 receptor binding are linked with increased growth of L6hIR cell xenografts in vivo

H. Hvid, B. Hansen, J. Brandt, 2020, Scientific Reports.

Quantitative Proteomics of Intestinal Mucosa From Male Mice Lacking Intestinal Epithelial Insulin Receptors

J. Ahnfelt-Rønne, T. Kislinger, H. Hvid, 2017, Endocrinology.

Partial rescue of in vivo insulin signalling in skeletal muscle by impaired insulin clearance in heterozygous carriers of a mutation in the insulin receptor gene

H. Vestergaard, K. Højlund, H. Beck-Nielsen, 2006, Diabetologia.

A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome

A. Chait, K. Bornfeldt, B. Hansen, 2018, Diabetes.

Cellular mechanism of nutritionally induced insulin resistance in Psammomys obesus: overexpression of protein kinase Cepsilon in skeletal muscle precedes the onset of hyperinsulinemia and hyperglycemia.

B. Hansen, Y. Ikeda, E. Ziv, 2001, Diabetes.

Glycogen concentration in human skeletal muscle: effect of prolonged insulin and glucose infusion

B. Hansen, E. Richter, B. Kiens, 1999, Scandinavian journal of medicine & science in sports.

The alpha2-5'AMP-activated protein kinase is a site 2 glycogen synthase kinase in skeletal muscle and is responsive to glucose loading.

B. Viollet, D. Hardie, P. Schjerling, 2004, Diabetes.

Glucose-induced insulin resistance of skeletal-muscle glucose transport and uptake.

B. Hansen, E. Richter, S. Hansen, 1988, The Biochemical journal.

l‐GLUTAMATE AND GLUTAMINE IMPROVE HAEMODYNAMIC FUNCTION AND RESTORE MYOCARDIAL GLYCOGEN CONTENT DURING POSTISCHAEMIC REPERFUSION: A RADIOACTIVE TRACER STUDY IN THE RAT ISOLATED HEART

H. Bøtker, B. Hansen, T. Nielsen, 2006, Clinical and experimental pharmacology & physiology.

Dysregulation of glycogen synthase COOH- and NH2-terminal phosphorylation by insulin in obesity and type 2 diabetes mellitus.

K. Højlund, H. Beck-Nielsen, B. Hansen, 2009, The Journal of clinical endocrinology and metabolism.

Cross-species reactive monoclonal antibodies against the extracellular domains of the insulin receptor and IGF1 receptor.

T. Pedersen, N. Blume, H. Hvid, 2019, Journal of immunological methods.

Sustained signalling from the insulin receptor after stimulation with insulin analogues exhibiting increased mitogenic potency.

H. Klein, B. Hansen, G. Danielsen, 1996, The Biochemical journal.

Impaired insulin activation and dephosphorylation of glycogen synthase in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment.

K. Højlund, H. Beck-Nielsen, B. Hansen, 2008, The Journal of clinical endocrinology and metabolism.

Synchronization in G0/G1 enhances the mitogenic response of cells overexpressing the human insulin receptor A isoform to insulin

B. Hansen, M. Oleksiewicz, Jette E. Svendsen, 2009, Cell Biology and Toxicology.

A novel high-affinity peptide antagonist to the insulin receptor.

J. Sturis, U. Ribel, B. Hansen, 2008, Biochemical and biophysical research communications.

Surface‐expressed insulin receptors as well as IGF‐I receptors both contribute to the mitogenic effects of human insulin and its analogues

B. Hansen, M. Oleksiewicz, N. Billestrup, 2015, Journal of applied toxicology : JAT.

Elucidating the Biological Roles of Insulin and Its Receptor in Murine Intestinal Growth and Function

J. Ahnfelt-Rønne, H. Hvid, B. Hansen, 2017, Endocrinology.

Phosphorylation-dependent Translocation of Glycogen Synthase to a Novel Structure during Glycogen Resynthesis*

D. Hardie, B. Hansen, J. Nielsen, 2005, Journal of Biological Chemistry.

Effects of glucagon-like peptide-1 (7-36)amide on insulin stimulated rat skeletal muscle glucose transport

B. Hansen, P. Jensen, E. Nepper-Christensen, 1998, Acta Diabetologica.

Preclinical exploration of combined glucagon inhibition and liver-preferential insulin for treatment of diabetes using in vitro assays and rat and mouse models

T. Pedersen, H. Hvid, B. Hansen, 2022, Diabetologia.

Synthesis and in vitro characterization of 1-(4-aminofurazan-3-yl)-5-dialkylaminomethyl-1H-[1,2,3]triazole-4-carboxylic acid derivatives. A new class of selective GSK-3 inhibitors.

B. Ursø, B. Hansen, Preben H Olesen, 2003, Journal of medicinal chemistry.

Unique expression pattern of the three insulin receptor family members in the rat mammary gland: dominance of IGF‐1R and IRR over the IR, and cyclical IGF‐1R expression

R. Klopfleisch, H. Hvid, I. Thorup, 2011, Journal of applied toxicology : JAT.

Stimulation of MC38 tumor growth by insulin analog X10 involves the serine synthesis pathway.

G. Stephanopoulos, M. V. Vander Heiden, H. Hvid, 2012, Endocrine-related cancer.

Insulin Analogues with Increased Mitogenic Potency – Are they Safe?

B. Hansen, 2008, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Activation of insulin receptors and IGF-1 receptors in COLO-205 colon cancer xenografts by insulin and insulin analogue X10 does not enhance growth under normo- or hypoglycaemic conditions

N. Blume, H. Hvid, B. Hansen, 2018, Diabetologia.

Molecular engineering of safe and efficacious oral basal insulin

E. Johansson, H. H. Refsgaard, U. Ribel, 2020, Nature Communications.

Structural and Biological Properties of the Drosophila Insulin-like Peptide 5 Show Evolutionary Conservation*

M. Tatar, V. Kiselyov, U. Ribel, 2010, The Journal of Biological Chemistry.

Isoform‐specific and exercise intensity‐dependent activation of 5′‐AMP‐activated protein kinase in human skeletal muscle

B. Hansen, J. Wojtaszewski, E. Richter, 2000, The Journal of physiology.

A-769662 activates AMPK beta1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle.

B. Hansen, J. Wojtaszewski, G. S. Olsen, 2009, American journal of physiology. Cell physiology.

Dual PPARα/γ activation provides enhanced improvement of insulin sensitivity and glycemic control in ZDF rats

J. Sturis, K. Wassermann, B. Hansen, 2003 .

Caffeine-induced impairment of insulin action but not insulin signaling in human skeletal muscle is reduced by exercise.

B. Ursø, W. Derave, F. Thong, 2002, Diabetes.

Muscle glycogen content affects insulin-stimulated glucose transport and protein kinase B activity.

W. Derave, B. Hansen, E. Richter, 2000, American journal of physiology. Endocrinology and metabolism.

Dual PPARalpha /gamma activation provides enhanced improvement of insulin sensitivity and glycemic control in ZDF rats.

J. Sturis, K. Wassermann, B. Hansen, 2003, American journal of physiology. Endocrinology and metabolism.

Intraintestinal and Parenteral Administration of an Insulin Analogue Leads to Comparable Activation of Signaling Downstream of the Insulin Receptor in the Small Intestine

J. Ahnfelt-Rønne, H. Hvid, B. Hansen, 2020, Journal of diabetes science and technology.

Agonism and Antagonism at the Insulin Receptor

B. Blagoev, V. Kiselyov, T. Pedersen, 2012, PloS one.

Use of Transgenic Models To Understand Effects of Exercise on Glucose Metabolism

B. Hansen, J. Wojtaszewski, 2002, Exercise and sport sciences reviews.

Differential aetiology and impact of phosphoinositide 3-kinase (PI3K) and Akt signalling in skeletal muscle on in vivo insulin action

P. Poulsen, A. Vaag, H. Beck-Nielsen, 2010, Diabetologia.

Akt2 influences glycogen synthase activity in human skeletal muscle through regulation of NH₂-terminal (sites 2 + 2a) phosphorylation.

P. Poulsen, A. Vaag, H. Beck-Nielsen, 2013, American journal of physiology. Endocrinology and metabolism.