C. Blackburn

发表

Discovery and optimization of N-acyl and N-aroylpyrazolines as B-Raf kinase inhibitors.

J. Williams, C. Blackburn, M. Duffey, 2010, Bioorganic & medicinal chemistry letters.

Potent histone deacetylase inhibitors derived from 4-(aminomethyl)-N-hydroxybenzamide with high selectivity for the HDAC6 isoform.

C. Blackburn, A. Gould, C. Barrett, 2013, Journal of medicinal chemistry.

Identification and characterization of amino-piperidinequinolones and quinazolinones as MCHr1 antagonists.

M. Maguire, Courtney A. Cullis, C. Blackburn, 2006, Bioorganic & medicinal chemistry letters.

Libraries of angiotensin converting enzyme inhibitors : Solid-phase synthesis and affinity selection

C. Blackburn, Hongqi Wang, Aruna Pingali, 1997 .

Parallel Synthesis of 3-Aminoimidazo[1,2-a]pyridines and -pyrazines by a New Three-Component Condensation.

C. Blackburn, B. Guan, K. Shiosaki, 2010 .

Characterization of a New Series of Non-covalent Proteasome Inhibitors with Exquisite Potency and Selectivity for the 20s Β5-subunit Figure S1 Activities of Compound 1 and Bortezomib in Cells

T. Soucy, E. Olhava, M. Sintchak, 2010 .

Histone deacetylase inhibitors derived from 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine and related heterocycles selective for the HDAC6 isoform.

C. Blackburn, A. Gould, C. Barrett, 2014, Bioorganic & medicinal chemistry letters.

Design, synthesis, and evaluation of naphthalene-sulfonamide antagonists of human CCR8.

S. Ghosh, T. Ocain, C. Blackburn, 2007, Journal of medicinal chemistry.

Tritium labelling of 2‐(O‐chlorophenyl)‐2‐(methylamino)‐Cyclohexanone (ketamine; CI‐581) by acid catalyzed exchange: An example of intramolecular competition for tritium between substituted aromatic and cyclohexanone rings

C. Blackburn, R. Ober, 1967 .

A three-component solid-phase synthesis of 3-aminoimidazo[1,2-a]azines

C. Blackburn, 1998 .

Parallel synthesis of 3-aminoimidazo[1,2-a]pyridines and pyrazines by a new three-component condensation

C. Blackburn, B. Guan, K. Shiosaki, 1998 .

A novel dealkylation affording 3-aminoimidazo[1,2-a]pyridines: access to new substitution patterns by solid-phase synthesis†

C. Blackburn, B. Guan, 2000 .

Polymer supports for solid‐phase organic synthesis

C. Blackburn, 1998 .

Identification and characterization of 4-aryl-3,4-dihydropyrimidin-2(1H)-ones as inhibitors of the fatty acid transporter FATP4.

Ying Sun, P. Raman, Courtney A. Cullis, 2006, Bioorganic & medicinal chemistry letters.

Redox-responsive crown ethers containing a direct link between the ferrocene redox-active centre and a benzo-crown ether. Crystal structures of a ferrocene benzo-15-crown-5 ligand and of its sodium complex

P. Beer, M. Drew, C. Blackburn, 1990 .

Identification and characterization of 4-aryl-3,4-dihydropyrimidin-2(1H)-ones as inhibitors of the fatty acid transporter FATP4.

Ying Sun, P. Raman, Courtney A. Cullis, 2006, Bioorganic & medicinal chemistry letters.

Discovery and characterization of aminopiperidinecoumarin melanin concentrating hormone receptor 1 antagonists.

Thomas Fey, Robin Shapiro, Ju Gao, 2005, Journal of medicinal chemistry.

FUNCTIONALIZED RESINS AND LINKERS FOR SOLID-PHASE SYNTHESIS OF SMALL MOLECULES

F. Albericio, C. Blackburn, S. Kates, 1999 .

Synthesis of 3-amino-1,2,4-benzothiadi- azine 1,1-dioxides via a tandem aza-Wittig/heterocumulene annulation.

S. Ghosh, C. Blackburn, G. Harriman, 2005, The Journal of organic chemistry.

Optimization of a series of dipeptides with a P3 β-neopentyl asparagine residue as non-covalent inhibitors of the chymotrypsin-like activity of human 20S proteasome

M. Sintchak, L. Dick, J. Blank, 2012 .

Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome.

Jonathan L Blank, Christopher Tsu, Christopher Blackburn, 2010, Bioorganic & medicinal chemistry letters.

Discovery and optimization of pyrazoline compounds as B-Raf inhibitors.

S. Langston, K. Garcia, C. Blackburn, 2010, Bioorganic & medicinal chemistry letters.

Redox-responsive crown ethers containing a conjugated link between the ferrocene moiety and a benzo crown ether

P. Beer, C. Blackburn, Harrison Sikanyika, 1990 .

Solid-phase synthesis of cyclic homodetic peptides.

C. Blackburn, S. Kates, 1997, Methods in enzymology.

Lewis acid complexes of 1,2-diketones and their derivatives: the synthesis of seven-membered rings

C. Blackburn, R. F. Childs, R. A. Kennedy, 1983 .

Metallocene bis(aza-crown ether) ligands and related compounds. Their syntheses, co-ordination chemistry, and electrochemical properties

A. Keefe, P. Beer, C. Blackburn, 1990 .

Lithium responsive fluorophores derived from Monoaza-12-crown-4 and coumarin. The influence of a methoxy side-arm on photophysical properties

C. Blackburn, K. LeCompte, M. E. Langmuir, 1994 .

Lithium redox-responsive ferrocene bis-tertiary amide derivatives

P. Beer, C. Blackburn, Harrison Sikanyika, 1988 .

Selective electrochemical recognition of the potassium guest cation in the presence of sodium and magnesium ions by a new ferrocenyl ionophore

P. Beer, C. Blackburn, Harrison Sikanyika, 1989 .

Redox-active crown ethers: transmission of cation binding to a redox centre via a conjugated link

C. Blackburn, J. Mcaleer, M. P. Andrews, 1987 .

Solid-phase synthesis of 2-amino-3-chloro-5- and 8-nitro-1,4-naphthoquinones: a new and general colorimetric test for resin-bound amines

C. Blackburn, 2005 .

Visual monitoring of solid-phase extraction using chromogenic fluorous synthesis supports.

C. Blackburn, 2012, ACS combinatorial science.

Synthesis of tritium labelled diphenhydramine hydrochloride (benadryl )

C. Blackburn, R. Ober, 1967 .

Specific tritium labelling of α -(p-methoxyphenyl)-α'-nitro-4 [3-(dimethylamino) propoxy] stilbene (CI-680) by catalytic deiodination

C. Blackburn, 1972 .

Carbon-14 and tritium labelling of m-(1-methyl-3-propyl-pyrrolidinyl)- phenol monohydrochloride (profadol; CI-572)

C. Blackburn, 1970 .

Identification of ortho-amino benzamides and nicotinamides as MCHr1 antagonists.

Anil Vasudevan, Christopher Blackburn, A. Vasudevan, 2005, Bioorganic & medicinal chemistry letters.

Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S β5-subunit

T. Soucy, E. Olhava, M. Sintchak, 2010, The Biochemical journal.

Design and optimization of potent and orally bioavailable tetrahydronaphthalene Raf inhibitors.

Yuan Tian, Hongbo Zeng, Mansoureh Rezaei, 2011, Journal of medicinal chemistry.

Identification of Potent and Selective Non-covalent Inhibitors of the Plasmodium falciparum Proteasome

M. Bogyo, L. Dick, C. Blackburn, 2014, Journal of the American Chemical Society.

Synthesis and biological evaluation of imidazole-based small molecule antagonists of the melanocortin 4 receptor (MC4-R).

Ping Li, Christopher Blackburn, C. Claiborne, 2004, Bioorganic & medicinal chemistry letters.

Identification and structure-activity relationships of a new series of Melanocortin-4 receptor antagonists.

C. Claiborne, C. Blackburn, T. Vos, 2006, Bioorganic & medicinal chemistry letters.

N,C-Capped dipeptides with selectivity for mycobacterial proteasome over human proteasomes: role of S3 and S1 binding pockets.

M. Sintchak, L. Dick, C. Nathan, 2013, Journal of the American Chemical Society.

Identification of aminopiperidine benzamides as MCHr1 antagonists.

A. Vasudevan, A. Souers, C. Blackburn, 2005, Bioorganic & medicinal chemistry letters.