Saurabh Menon

发表

Discovery and optimization of N-acyl and N-aroylpyrazolines as B-Raf kinase inhibitors.

J. Williams, C. Blackburn, M. Duffey, 2010, Bioorganic & medicinal chemistry letters.

Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors.

S. Adhikari, J. Brownell, Anya Lublinsky, 2020, Bioorganic & medicinal chemistry.

Genome-wide siRNA screen for modulators of cell death induced by proteasome inhibitor bortezomib.

E. Lightcap, Jie Yu, J. Blank, 2010, Cancer research.

Discovery and optimization of pyrazoline compounds as B-Raf inhibitors.

S. Langston, K. Garcia, C. Blackburn, 2010, Bioorganic & medicinal chemistry letters.

ACE2 X-Ray Structures Reveal a Large Hinge-bending Motion Important for Inhibitor Binding and Catalysis

Saurabh Menon, T. Parsons, M. Pantoliano, 2004, Journal of Biological Chemistry.

A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment

S. Tirrell, J. Newcomb, T. Soucy, 2018, Nature Medicine.

Optimization of tetrahydronaphthalene inhibitors of Raf with selectivity over hERG.

S. Adhikari, H. Mizutani, Mansoureh Rezaei, 2016, Bioorganic & medicinal chemistry letters.

TAK-676: A Novel Stimulator of Interferon Genes (STING) Agonist Promoting Durable IFN-dependent Antitumor Immunity in Preclinical Studies

T. Traore, V. Kolev, M. Okaniwa, 2022, Cancer research communications.

Design and optimization of potent and orally bioavailable tetrahydronaphthalene Raf inhibitors.

Yuan Tian, Hongbo Zeng, Mansoureh Rezaei, 2011, Journal of medicinal chemistry.

Automated High-Throughput Flow Cytometry for High-Content Screening in Antibody Development

Samson King, Patrick Leroy, Saurabh Menon, 2018, SLAS discovery : advancing life sciences R & D.

Use of combination treatment with the investigational RAF kinase inhibitor MLN2480 and the investigational MEK kinase inhibitor TAK-733 on the growth of BRAF-mutant and RAS-mutant preclinical models of melanoma and CRC.

J. Mettetal, P. Vincent, Julie Zhang, 2013 .