D. Gelain

发表

Retinol induces the ERK1/2-dependent phosphorylation of CREB through a pathway involving the generation of reactive oxygen species in cultured Sertoli cells.

I. Izquierdo, M. Cammarota, L. Bevilaqua, 2006, Cellular signalling.

Ultra high frequency-electromagnetic field irradiation during pregnancy leads to an increase in erythrocytes micronuclei incidence in rat offspring.

H. Ferreira, D. Gelain, F. Dal-Pizzol, 2006, Life sciences.

Characterization and modulation of microglial phenotypes in an animal model of severe sepsis

D. Gelain, F. Dal-Pizzol, J. Moreira, 2019, Journal of cellular and molecular medicine.

Delayed neurochemical effects of prenatal exposure to MeHg in the cerebellum of developing rats.

D. Gelain, J. Moreira, L. Heimfarth, 2018, Toxicology letters.

Nuclear RXRα and RXRβ receptors exert distinct and opposite effects on RA-mediated neuroblastoma differentiation.

Diana C. Rostirolla, D. Gelain, J. Moreira, 2019, Biochimica et biophysica acta. Molecular cell research.

Changes in Cell Cycle and Up-Regulation of Neuronal Markers During SH-SY5Y Neurodifferentiation by Retinoic Acid are Mediated by Reactive Species Production and Oxidative Stress

Diana C. Rostirolla, D. Gelain, A. Zanotto-Filho, 2017, Molecular Neurobiology.

Oxidative stress in chronic obstructive pulmonary disease patients submitted to a rehabilitation program.

M. Andrades, D. Gelain, Ricardo Aurino Pinho, 2007, Respiratory medicine.

Antioxidant and Anti-Inflammatory Properties of Anacardium occidentale Leaf Extract

D. Gelain, J. Moreira, R. D. Albanus, 2017, Evidence-based complementary and alternative medicine : eCAM.

Subcellular distribution of human tyrosine hydroxylase isoforms 1 and 4 in SH‐SY5Y cells

D. Gelain, J. Moreira, P. Dickson, 2019, Journal of cellular biochemistry.

Retinol activates tyrosine hydroxylase acutely by increasing the phosphorylation of serine40 and then serine31 in bovine adrenal chromaffin cells

L. Bevilaqua, D. Gelain, J. Moreira, 2007, Journal of neurochemistry.

Vitamin A (retinol) downregulates the receptor for advanced glycation endproducts (RAGE) by oxidant-dependent activation of p38 MAPK and NF-kB in human lung cancer A549 cells.

D. Gelain, J. Moreira, F. Zeidán-Chuliá, 2013, Cellular signalling.

Vitamin A supplementation to pregnant and breastfeeding female rats induces oxidative stress in the neonatal lung.

D. Gelain, J. Moreira, M. Pasquali, 2010, Reproductive toxicology.

Determination of chemical and physical properties of Hyptis pectinata essential oil and their redox active profile

P. Alves, D. Gelain, J. Moreira, 2012 .

Effect of Paullinia cupana Mart. Commercial Extract During the Aging of Middle Age Wistar Rats: Differential Effects on the Hippocampus and Striatum

D. Gelain, J. Moreira, F. Zeidán-Chuliá, 2017, Neurochemical Research.

L‐NAME co‐treatment prevent oxidative damage in the lung of adult Wistar rats treated with vitamin A supplementation

Marcos Roberto Oliveira, D. Gelain, J. Moreira, 2012, Cell biochemistry and function.

Vitamin A (retinol) up-regulates the receptor for advanced glycation endproducts (RAGE) through p38 and Akt oxidant-dependent activation.

D. Gelain, J. Moreira, M. A. de Bittencourt Pasquali, 2011, Toxicology.

VITAMIN A SUPPLEMENTATION INDUCES OXIDATIVE STRESS AND DECREASES THE IMMUNOCONTENT OF CATALASE AND SUPEROXIDE DISMUTASE IN RAT LUNGS

F. Klamt, Marcos Roberto Oliveira, D. Gelain, 2009, Experimental lung research.

Retinol up-regulates the receptor for advanced glycation endproducts (RAGE) by increasing intracellular reactive species.

D. Gelain, A. Zanotto-Filho, J. Moreira, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

Participation of 47C>T SNP (Ala-9Val polymorphism) of the SOD2 gene in the intracellular environment of human peripheral blood mononuclear cells with and without lipopolysaccharides

D. Gelain, J. Moreira, C. Alho, 2012, Molecular and Cellular Biochemistry.

Effects of different products of peach (Prunus persica L. Batsch) from a variety developed in southern Brazil on oxidative stress and inflammatory parameters in vitro and ex vivo

D. Gelain, J. Moreira, T. K. Rabelo, 2014, Journal of clinical biochemistry and nutrition.

Retinol induces morphological alterations and proliferative focus formation through free radical-mediated activation of multiple signaling pathways

D. Gelain, J. Moreira, F. Caregnato, 2012, Acta Pharmacologica Sinica.

Antioxidants improve oxaliplatin-induced peripheral neuropathy in tumor-bearing mice model: role of spinal cord oxidative stress and inflammation.

D. Gelain, A. Zanotto-Filho, J. Moreira, 2021, The journal of pain.

Focussed microarray analysis of apoptosis in periodontitis and its potential pharmacological targeting by carvacrol.

D. Gelain, J. Moreira, V. Uitto, 2014, Archives of oral biology.

Antioxidant Activity and Mechanisms of Action of Natural Compounds Isolated from Lichens: A Systematic Review

D. Gelain, J. Moreira, J. Almeida, 2014, Molecules.

Anticancer activity of flavonoids isolated from Achyrocline satureioides in gliomas cell lines.

C. Klein, F. Figueiró, D. Gelain, 2018, Toxicology in vitro : an international journal published in association with BIBRA.

PACAP stimulates the sustained phosphorylation of tyrosine hydroxylase at serine 40.

D. Gelain, P. Dickson, P. Dunkley, 2007, Cellular signalling.

Transcriptomic analysis reveals pH-responsive antioxidant gene networks.

F. Klamt, D. Gelain, J. Moreira, 2012, Frontiers in bioscience.

Chronic ozone exposure alters the secondary metabolite profile, antioxidant potential, anti-inflammatory property, and quality of red pepper fruit from Capsicum baccatum.

D. Gelain, A. Zanotto-Filho, J. Moreira, 2016, Ecotoxicology and environmental safety.

Redox characterization of usnic acid and its cytotoxic effect on human neuron-like cells (SH-SY5Y).

D. Gelain, J. Moreira, F. Zeidán-Chuliá, 2012, Toxicology in vitro : an international journal published in association with BIBRA.

Anti-RAGE antibody selectively blocks acute systemic inflammatory responses to LPS in serum, liver, CSF and striatum

G. Leipnitz, D. Gelain, J. Moreira, 2017, Brain, Behavior, and Immunity.

Non-genomic, direct modulatory effect of 17β-estradiol, progesterone and their synthetic derivatives on the activity of human erythrocyte CuZn superoxide dismutase

D. Gelain, J. Moreira, D. Kemerich, 2013, Free radical research.

The NF kappa B-mediated control of RS and JNK signaling in vitamin A-treated cells: duration of JNK-AP-1 pathway activation may determine cell death or proliferation.

F. Klamt, D. Gelain, A. Zanotto-Filho, 2009, Biochemical pharmacology.

Major Components of Energy Drinks (Caffeine, Taurine, and Guarana) Exert Cytotoxic Effects on Human Neuronal SH-SY5Y Cells by Decreasing Reactive Oxygen Species Production

P. Ambrosi, D. Gelain, F. Zeidán-Chuliá, 2013, Oxidative medicine and cellular longevity.

Anti-inflammatory and antixidant properties of blend formulated with compounds of Malpighia emarginata D.C (acerola) and Camellia sinensis L. (green tea) in lipopolysaccharide-stimulated RAW 264.7 macrophages.

D. Gelain, J. Moreira, Hugo Miguel Lisboa Oliveira, 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Putative model for heat shock protein 70 complexation with receptor of advanced glycation end products through fluorescence proximity assays and normal mode analyses

R. Ligabue-Braun, D. Gelain, J. Moreira, 2016, Cell Stress and Chaperones.

N-acetyl-cysteine inhibits liver oxidative stress markers in BALB/c mice infected with Leishmania amazonensis

D. Gelain, F. Dal-Pizzol, J. Moreira, 2017, Memorias do Instituto Oswaldo Cruz.

The effects of retinol oral supplementation in 6-hydroxydopamine dopaminergic denervation model in Wistar rats

D. Gelain, J. Moreira, L. Petiz, 2019, Neurochemistry International.

Redox properties and cytoprotective actions of atranorin, a lichen secondary metabolite.

D. Gelain, J. Moreira, F. Caregnato, 2011, Toxicology in vitro : an international journal published in association with BIBRA.

Retinol (Vitamin A) Increases α-Synuclein, β-Amyloid Peptide, Tau Phosphorylation and RAGE Content in Human SH-SY5Y Neuronal Cell Line

D. Gelain, J. Moreira, M. A. de Bittencourt Pasquali, 2017, Neurochemical Research.

Antioxidant Profile Characterization of a Commercial Paullinia cupana (Guarana) Extracts

D. Gelain, A. Zanotto-Filho, J. Moreira, 2016 .

Shikimic acid inhibits LPS-induced cellular pro-inflammatory cytokines and attenuates mechanical hyperalgesia in mice.

D. Gelain, J. Moreira, L. Quintans-Júnior, 2016, International immunopharmacology.

Redox properties of Abarema cochliacarpos (Gomes) Barneby & Grime (Fabaceae) stem bark ethanol extract and fractions

D. Gelain, J. Moreira, C. Estevam, 2013, Natural product research.

Antinociceptive Activity and Redox Profile of the Monoterpenes (+)-Camphene, p-Cymene, and Geranyl Acetate in Experimental Models

D. Gelain, J. Moreira, L. Quintans-Júnior, 2013, ISRN toxicology.

Schistosoma mansoni infection causes oxidative stress and alters receptor for advanced glycation endproduct (RAGE) and tau levels in multiple organs in mice.

D. Gelain, R. B. de Oliveira, J. Moreira, 2013, International journal for parasitology.

Effect of N-salicyloyltryptamine (STP), a novel tryptamine analogue, on parameters of cell viability, oxidative stress, and immunomodulation in RAW 264.7 macrophages

D. Gelain, J. Moreira, J. Barbosa-Filho, 2013, Cell Biology and Toxicology.

Antioxidant, antinociceptive, and anti-inflammatory properties of the ethanolic extract of Combretum duarteanum in rodents.

D. Gelain, L. Quintans-Júnior, J. Tavares, 2011, Journal of medicinal food.

Coadministration of Branched-Chain Amino Acids and Lipopolysaccharide Causes Matrix Metalloproteinase Activation and Blood–Brain Barrier Breakdown

D. Gelain, F. Dal-Pizzol, J. Moreira, 2014, Molecular Neurobiology.

Redox homeostasis is compromised in vivo by the metabolites accumulating in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency in rat cerebral cortex and liver

G. Leipnitz, M. Wajner, C. Fernandes, 2013, Free radical research.

Evidence of increased reactive species formation by retinol, but not retinoic acid, in PC12 cells.

D. Gelain, J. Moreira, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

Mitochondrial bioenergetics deregulation caused by long-chain 3-hydroxy fatty acids accumulating in LCHAD and MTP deficiencies in rat brain: a possible role of mPTP opening as a pathomechanism in these disorders?

M. Wajner, D. Gelain, N. Gregersen, 2014, Biochimica et biophysica acta.

Retinoic acid downregulates thiol antioxidant defences and homologous recombination while promotes A549 cells sensitization to cisplatin.

Diana C. Rostirolla, L. Grun, F. Barbé-Tuana, 2019, Cellular signalling.

Redox-Active Profile Characterization of Remirea maritima Extracts and Its Cytotoxic Effect in Mouse Fibroblasts (L929) and Melanoma (B16F10) Cells

D. Gelain, J. Moreira, M. Fonseca, 2015, Molecules.

Anti-inflammatory property and redox profile of the leaves extract from Morinda citrifolia L.

D. Gelain, L. Quintans-Júnior, B. Lima, 2015 .

Supplementation with Achyrocline satureioides Inflorescence Extracts to Pregnant and Breastfeeding Rats Induces Tissue-Specific Changes in Enzymatic Activity and Lower Neonatal Survival

D. Gelain, J. Moreira, F. Zeidán-Chuliá, 2017, Biomedicines.

Structure–Activity Relationship of Terpenes with Anti‐Inflammatory Profile – A Systematic Review

D. Gelain, J. Moreira, L. Quintans-Júnior, 2014, Basic & clinical pharmacology & toxicology.

Vitamin A treatment induces apoptosis through an oxidant‐dependent activation of the mitochondrial pathway

F. Klamt, D. Gelain, F. Dal-Pizzol, 2008, Cell biology international.

Role of vitamin A oral supplementation on oxidative stress and inflammatory response in the liver of trained rats.

C. Matté, D. Gelain, J. Moreira, 2017, Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.

Choline and Cystine Deficient Diets in Animal Models with Hepatocellular Injury: Evaluation of Oxidative Stress and Expression of RAGE, TNF-α, and IL-1β

D. Gelain, Kívia Queiroz de Andrade, F. A. Moura, 2015, Oxidative medicine and cellular longevity.

Host–guest inclusion complexation of β-cyclodextrin and hecogenin acetate to enhance anti-hyperalgesic effect in an animal model of musculoskeletal pain

G. Zengin, D. Gelain, J. Almeida, 2017 .

Vitamin A Oral Supplementation Induces Oxidative Stress and Suppresses IL-10 and HSP70 in Skeletal Muscle of Trained Rats

C. Matté, D. Gelain, J. Moreira, 2017, Nutrients.

Morphological and oxidative alterations on Sertoli cells cytoskeleton due to retinol-induced reactive oxygen species

F. Klamt, D. Gelain, M. Polydoro, 2005, Molecular and Cellular Biochemistry.

Characterization and Evaluation of the Antioxidant Activity of Calamusenone, a Major Component of Hyptis pectinata (L.) Poit Essential Oil

P. Alves, D. Gelain, J. Moreira, 2017 .

Chemical composition, antinociceptive, anti-inflammatory and redox properties in vitro of the essential oil from Remirea maritima Aubl. (Cyperaceae)

D. Gelain, J. Moreira, A. Araújo, 2014, BMC Complementary and Alternative Medicine.

Phytochemical screening, antinociceptive and anti-inflammatory activities of Chrysopogon zizanioides essential oil

P. Alves, D. Gelain, J. Moreira, 2012 .

Article 27.indd

Paulina, José, P. Alves, 2012 .

Carvacrol suppresses LPS-induced pro-inflammatory activation in RAW 264.7 macrophages through ERK1/2 and NF-kB pathway.

D. Gelain, J. Moreira, L. Quintans-Júnior, 2019, International immunopharmacology.

Antinociceptive Activity of Atranorin in Mice Orofacial Nociception Tests

D. Gelain, J. Moreira, J. M. D. Santana, 2010, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Sperm quality and oxidative status as affected by homogenization of liquid-stored boar semen diluted in short- and long-term extenders.

D. Gelain, J. Moreira, M. Bernardi, 2017, Animal reproduction science.

Apoptotic signaling pathways induced by acute administration of branched-chain amino acids in an animal model of maple syrup urine disease

D. Gelain, J. Moreira, G. Scaini, 2017, Metabolic Brain Disease.

LDL Receptor Deficiency Does not Alter Brain Amyloid-β Levels but Causes an Exacerbation of Apoptosis.

A. D. de Bem, D. Gelain, J. Moreira, 2019, Journal of Alzheimer's disease : JAD.

Retinoic acid induces apoptosis by a non-classical mechanism of ERK1/2 activation.

M. Cammarota, D. Gelain, A. Zanotto-Filho, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

Retinol and retinoic acid modulate catalase activity in Sertoli cells by distinct and gene expression-independent mechanisms.

F. Klamt, D. Gelain, A. Zanotto-Filho, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

Retinol increases catalase activity and protein content by a reactive species-dependent mechanism in Sertoli cells.

F. Klamt, D. Gelain, A. Zanotto-Filho, 2008, Chemico-biological interactions.

Xanthine oxidase activity in patients with sepsis.

M. Andrades, D. Gelain, F. Dal-Pizzol, 2008, Clinical biochemistry.

Chronic administration of branched-chain amino acids impairs spatial memory and increases brain-derived neurotrophic factor in a rat model

J. Quevedo, D. Gelain, J. Moreira, 2013, Journal of Inherited Metabolic Disease.

Gold nanoparticles application to the treatment of brain dysfunctions related to metabolic diseases: evidence from experimental studies

D. Gelain, M. S. Rodrigues, P. C. Silveira, 2022, Metabolic Brain Disease.

Morinda citrifolia Linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration.

D. Gelain, L. Bonjardim, L. Quintans-Júnior, 2011, Journal of medicinal food.

A systematic review of human antioxidant genes.

F. Klamt, D. Gelain, J. Moreira, 2009, Frontiers in bioscience.

Serum Heat Shock Protein 70 Levels, Oxidant Status, and Mortality in Sepsis

J. Quevedo, D. Gelain, F. Dal-Pizzol, 2011, Shock.

Bioassay-guided evaluation of antioxidant and antinociceptive activities of carvacrol.

D. Gelain, J. Moreira, L. Bonjardim, 2010, Basic & clinical pharmacology & toxicology.

Antinociceptive effects of citronellal in formalin-, capsaicin-, and glutamate-induced orofacial nociception in rodents and its action on nerve excitability.

D. Gelain, D. P. de Sousa, L. Bonjardim, 2010, Journal of orofacial pain.

Antinociceptive, anti-inflammatory and antioxidant activities of aqueous extract from Remirea maritima (Cyperaceae).

D. Gelain, A. Barison, L. Bonjardim, 2013, Journal of ethnopharmacology.

Modulation in reproductive tissue redox profile in sexually receptive female rats after short-term exposure to male chemical cues.

D. Gelain, J. Moreira, M. R. de Oliveira, 2009, Chemical senses.

Plasma oxidative parameters and mortality in patients with severe burn injury

M. Andrades, D. Gelain, F. Dal-Pizzol, 2003, Intensive Care Medicine.

Metabolism of amino acids by cultured rat Sertoli cells.

E. A. Bernard, D. Gelain, M. Perry, 2005, Metabolism: clinical and experimental.

Extracellular Inosine is Modulated by H2O2 and Protects Sertoli Cells against Lipoperoxidation and Cellular Injury

E. A. Bernard, D. Gelain, J. C. Fonseca Moreira, 2004, Free radical research.

Extracellular purines from cells of seminiferous tubules

E. A. Bernard, D. Gelain, L. F. de Souza, 2003, Molecular and Cellular Biochemistry.

Inhibition of MDR1 expression by retinol treatment increases sensitivity to etoposide (VP16) in human neoplasic cell line.

F. Klamt, I. Grivicich, D. Gelain, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

Is There a Role for High Mobility Group Box 1 and the Receptor for Advanced Glycation End Products in the Genesis of Long-term Cognitive Impairment in Sepsis Survivors?

J. Quevedo, D. Gelain, F. Dal-Pizzol, 2012, Molecular medicine.

Participation of 47C>T SNP (Ala-9Val polymorphism) of the SOD2 gene in the intracellular environment of human peripheral blood mononuclear cells with and without lipopolysaccharides

D. Gelain, J. Moreira, C. Alho, 2012, Molecular and Cellular Biochemistry.

Antinociceptive action and redox properties of citronellal, an essential oil present in lemongrass.

D. Gelain, J. Moreira, D. P. de Sousa, 2011, Journal of medicinal food.

Bioactive compounds and protective effect of red and black rice brans extracts in human neuron-like cells (SH-SY5Y).

D. Gelain, J. Moreira, Eliseu Rodrigues, 2018, Food research international.

Acute Administration of Branched-Chain Amino Acids Increases the Pro-BDNF/Total-BDNF Ratio in the Rat Brain

D. Gelain, J. Moreira, M. Bogo, 2015, Neurochemical Research.

Extracellular inosine participates in tumor necrosis factor-alpha induced nitric oxide production in cultured Sertoli cells

E. A. Bernard, D. Gelain, M. Zim, 2006, Molecular and Cellular Biochemistry.

Extracellular inosine modulates ERK 1/2 and p38 phosphorylation in cultured Sertoli cells: possible participation in TNF-alpha modulation of ERK 1/2.

E. A. Bernard, D. Gelain, G. Lenz, 2005, Life sciences.

Effects of follicle-stimulating hormone and vitamin A upon purinergic secretion by rat Sertoli cells

D. Gelain, F. Dal-Pizzol, J. Moreira, 2005, Molecular and Cellular Biochemistry.

Changes in ectonucleotidase activities in rat Sertoli cells during sexual maturation

D. Gelain, E. Casali, A. Battastini, 2003, Molecular and Cellular Biochemistry.

Ectonucleotidase activities in Sertoli cells from immature rats.

E. A. Bernard, D. Gelain, E. Casali, 2001, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Review of the biological properties and toxicity of usnic acid

D. Gelain, L. Quintans-Júnior, A. Araújo, 2015, Natural product research.

β‐Cyclodextrin‐complexed (−)‐linalool produces antinociceptive effect superior to that of (−)‐linalool in experimental pain protocols

D. Gelain, J. Almeida, L. Quintans-Júnior, 2013, Basic & clinical pharmacology & toxicology.

Sulfite disrupts brain mitochondrial energy homeostasis and induces mitochondrial permeability transition pore opening via thiol group modification.

G. Leipnitz, M. Wajner, A. Wyse, 2014, Biochimica et biophysica acta.

Improvement of p-cymene antinociceptive and anti-inflammatory effects by inclusion in β-cyclodextrin.

D. Gelain, L. Bonjardim, L. Quintans-Júnior, 2013, Phytomedicine : international journal of phytotherapy and phytopharmacology.

A new animal diet based on human Western diet is a robust diet-induced obesity model: comparison to high-fat and cafeteria diets in term of metabolic and gut microbiota disruption

D. Gelain, J. Moreira, T. K. Rabelo, 2018, International Journal of Obesity.

Natural Bioactive Compounds from Fruits and Vegetables as Health Promoters: Part 2

E. Fernandes, A. C. Galvis-Sánchez, A. Duarte, 2016 .

Development of standardized extractive solution from Lippia sidoides by factorial design and their redox active profile

D. Gelain, J. Moreira, L. Soares, 2015 .

In vitro scavenging capacity of Organic Silicium (oral anti-aging) against reactive oxygen and nitrogen species

J. C. Cardoso, D. Gelain, B. Lima, 2014 .

Effects of Achyrocline satureioides Inflorescence Extracts against Pathogenic Intestinal Bacteria: Chemical Characterization, In Vitro Tests, and In Vivo Evaluation

L. Grun, F. Barbé-Tuana, D. Gelain, 2017, Evidence-based complementary and alternative medicine : eCAM.

Characterization of Blood Oxidative Stress in Type 2 Diabetes Mellitus Patients: Increase in Lipid Peroxidation and SOD Activity

D. Gelain, J. Moreira, M. Goulart, 2012, Oxidative medicine and cellular longevity.

Passiflora manicata (Juss.) aqueous leaf extract protects against reactive oxygen species and protein glycation in vitro and ex vivo models.

D. Gelain, J. Moreira, E. Schenkel, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Comparison between proliferative and neuron-like SH-SY5Y cells as an in vitro model for Parkinson disease studies

Fabio Klamt, Alfeu Zanotto-Filho, Flávio Kapczinski, 2010, Brain Research.

Induced pluripotent stem cell-derived astrocytes from patients with schizophrenia exhibit an inflammatory phenotype that affects vascularization

V. Palma, J. Nascimento, D. Gelain, 2022, bioRxiv.

Receptor for advanced glycation end products mediates sepsis-triggered amyloid-β accumulation, Tau phosphorylation, and cognitive impairment

J. Quevedo, D. Gelain, F. Dal-Pizzol, 2017, The Journal of Biological Chemistry.

Acute Brain Inflammation and Oxidative Damage Are Related to Long-Term Cognitive Deficits and Markers of Neurodegeneration in Sepsis-Survivor Rats

J. Quevedo, D. Gelain, F. Dal-Pizzol, 2014, Molecular Neurobiology.

Matrix Metalloproteinase-2 and Metalloproteinase-9 Activities are Associated with Blood–Brain Barrier Dysfunction in an Animal Model of Severe Sepsis

J. Quevedo, D. Gelain, F. Dal-Pizzol, 2013, Molecular Neurobiology.

Guarana (Paullinia cupana Mart.) Prevents β‐Amyloid Aggregation, Generation of Advanced Glycation‐end Products (AGEs), and Acrolein‐Induced Cytotoxicity on Human Neuronal‐Like Cells

D. Gelain, J. Moreira, F. Zeidán-Chuliá, 2014, Phytotherapy research : PTR.

Immunomodulatory Effect of Bifidobacterium, Lactobacillus, and Streptococcus Strains of Paraprobiotics in Lipopolysaccharide-Stimulated Inflammatory Responses in RAW-264.7 Macrophages

D. Gelain, F. Dal-Pizzol, P. Feuser, 2021, Current Microbiology.

NFκB inhibitors induce cell death in glioblastomas.

Alfeu Zanotto-Filho, Rodrigo J S Dalmolin, José Cláudio Fonseca Moreira, 2011, Biochemical pharmacology.

Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas.

I. J. Bristot, F. Figueiró, D. Gelain, 2015, Cancer letters.

In Vitro Neuroprotective Effect of Shikimic Acid Against Hydrogen Peroxide-Induced Oxidative Stress

D. Gelain, J. Moreira, F. Zeidán-Chuliá, 2015, Journal of Molecular Neuroscience.

In Vitro Neuroprotective Effect of Shikimic Acid Against Hydrogen Peroxide-Induced Oxidative Stress

D. Gelain, J. Moreira, F. Zeidán-Chuliá, 2015, Journal of Molecular Neuroscience.

Thioredoxin reductase-1 levels are associated with NRF2 pathway activation and tumor recurrence in non-small cell lung cancer.

D. Gelain, A. Zanotto-Filho, J. Moreira, 2021, Free radical biology & medicine.

Inflammatory landscape of human brain tumors reveals an NFκB dependent cytokine pathway associated with mesenchymal glioblastoma.

D. Gelain, A. Zanotto-Filho, J. Moreira, 2017, Cancer letters.

Hypoxia-Inducible Factor-1α (HIF-1α) Inhibition Impairs Retinoic Acid-Induced Differentiation in SH-SY5Y Neuroblastoma Cells, Leading to Reduced Neurite Length and Diminished Gene Expression Related to Cell Differentiation

D. Gelain, J. Moreira, J. Gasparotto, 2021, Neurochemical research.

Targeted inhibition of RAGE in substantia nigra of rats blocks 6-OHDA–induced dopaminergic denervation

D. Gelain, J. Moreira, M. Pasquali, 2017, Scientific Reports.

Caryocar brasiliense camb protects against genomic and oxidative damage in urethane-induced lung carcinogenesis

D. Gelain, C. Grisolia, E. Parra, 2015, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

COX-2 promotes mammary adipose tissue inflammation, local estrogen biosynthesis, and carcinogenesis in high-sugar/fat diet treated mice.

D. Gelain, A. Zanotto-Filho, J. Moreira, 2021, Cancer letters.

Developmental neurotoxicity of the hippocampus following in utero exposure to methylmercury: impairment in cell signaling

D. Gelain, J. Moreira, R. Pessoa-Pureur, 2017, Archives of Toxicology.

Animal Models of Metabolic Disorders in the Study of Neurodegenerative Diseases: An Overview

A. D. de Bem, D. Gelain, J. Moreira, 2021, Frontiers in Neuroscience.

Anti-NMDA Receptor Autoantibody Is an Independent Predictor of Hospital Mortality but Not Brain Dysfunction in Septic Patients

D. Gelain, F. Dal-Pizzol, R. Walz, 2019, Front. Neurol..

Activated peripheral blood mononuclear cell mediators trigger astrocyte reactivity

F. Klamt, D. Gelain, D. Leffa, 2019, Brain, Behavior, and Immunity.

Brain markers of neurodegeneration in sepsis survivor rats

J. Quevedo, D. Gelain, F. Dal-Pizzol, 2013, Critical Care.

Acute Brain Inflammation and Oxidative Damage Are Related to Long-Term Cognitive Deficits and Markers of Neurodegeneration in Sepsis-Survivor Rats

J. Quevedo, D. Gelain, F. Dal-Pizzol, 2013, Molecular Neurobiology.

Intranasal HSP70 administration protects against dopaminergic denervation and modulates neuroinflammatory response in the 6-OHDA rat model

D. Gelain, J. Moreira, J. Gasparotto, 2021, Brain, behavior, & immunity - health.

Obesity associated with coal ash inhalation triggers systemic inflammation and oxidative damage in the hippocampus of rats.

D. Gelain, Luis Felipe Silva Oliveira, J. C. Fonseca Moreira, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Oral administration of carvacrol/β-cyclodextrin complex protects against 6-hydroxydopamine-induced dopaminergic denervation

D. Gelain, J. Moreira, L. Quintans-Júnior, 2019, Neurochemistry International.

Systemic Inflammation Changes the Site of RAGE Expression from Endothelial Cells to Neurons in Different Brain Areas

D. Gelain, J. Moreira, T. K. Rabelo, 2018, Molecular Neurobiology.

Neurobehavioral and oxidative stress alterations following methylmercury and retinyl palmitate co‐administration in pregnant and lactating rats and their offspring

D. Gelain, D. P. Moraes, J. C. Fonseca Moreira, 2018, Neurotoxicology.

Effects of methylmercury and retinol palmitate co-administration in rats during pregnancy and breastfeeding: Metabolic and redox parameters in dams and their offspring.

D. Gelain, J. Moreira, D. P. Moraes, 2018, Ecotoxicology and environmental safety.

BRCA-1 depletion impairs pro-inflammatory polarization and activation of RAW 264.7 macrophages in a NF-κB-dependent mechanism

F. Figueiró, D. Gelain, A. Zanotto-Filho, 2019, Molecular and Cellular Biochemistry.

Hecogenin acetate inhibits reactive oxygen species production and induces cell cycle arrest and senescence in the A549 human lung cancer cell line.

D. Gelain, J. Moreira, L. Quintans-Júnior, 2014, Anti-cancer agents in medicinal chemistry.

The oxidation of HSP70 is associated with functional impairment and lack of stimulatory capacity

D. Gelain, A. Zanotto-Filho, J. Moreira, 2014, Cell Stress and Chaperones.

Vitamin A supplementation for different periods alters oxidative parameters in lungs of rats.

F. Klamt, D. Gelain, J. Moreira, 2009, Journal of medicinal food.

Hydroethanolic extracts from different genotypes of açaí (Euterpe oleracea) presented antioxidant potential and protected human neuron-like cells (SH-SY5Y).

D. Gelain, J. Moreira, A. Jablonski, 2017, Food chemistry.

Supplementation with vitamin A enhances oxidative stress in the lungs of rats submitted to aerobic exercise.

C. Matté, D. Gelain, A. Zanotto-Filho, 2015, Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.

Gene Expression Profile of NF-κB, Nrf2, Glycolytic, and p53 Pathways During the SH-SY5Y Neuronal Differentiation Mediated by Retinoic Acid

D. Gelain, J. Moreira, R. D. Albanus, 2014, Molecular Neurobiology.

Antioxidant Therapies for Neurodegenerative Diseases: Mechanisms, Current Trends, and Perspectives

D. Gelain, M. Trujillo, Guilherme Antônio Behr, 2012, Oxidative medicine and cellular longevity.

Obese rats are more vulnerable to inflammation, genotoxicity and oxidative stress induced by coal dust inhalation than non-obese rats.

J. da Silva, F. R. da Silva, D. Gelain, 2018, Ecotoxicology and environmental safety.

Short and long TNF‐alpha exposure recapitulates canonical astrogliosis events in human‐induced pluripotent stem cells‐derived astrocytes

D. Gelain, J. Moreira, A. Ventura, 2020, Glia.

Short and long TNF-alpha exposure recapitulates canonical astrogliosis events in human induced pluripotent stem cells-derived astrocytes

D. Gelain, J. Moreira, A. Ventura, 2019, bioRxiv.

Glycine Administration Alters MAPK Signaling Pathways and Causes Neuronal Damage in Rat Brain: Putative Mechanisms Involved in the Neurological Dysfunction in Nonketotic Hyperglycinemia

G. Leipnitz, M. Wajner, D. Gelain, 2017, Molecular Neurobiology.

The oxidation of HSP70 is associated with functional impairment and lack of stimulatory capacity

D. Gelain, A. Zanotto-Filho, J. Moreira, 2014, Cell Stress and Chaperones.

Altered expression of Alzheimer's disease-related genes in the cerebellum of autistic patients: a model for disrupted brain connectome and therapy

M. Casanova, A. Verkhratsky, D. Gelain, 2014, Cell Death and Disease.

Effects of 47C allele (rs4880) of the SOD2 gene in the production of intracellular reactive species in peripheral blood mononuclear cells with and without lipopolysaccharides induction

I. J. Bristot, D. Gelain, J. Moreira, 2014, Free radical research.

High fat diet-induced obesity causes a reduction in brain tyrosine hydroxylase levels and non-motor features in rats through metabolic dysfunction, neuroinflammation and oxidative stress

D. Gelain, J. Moreira, L. Heimfarth, 2020, Nutritional neuroscience.

PERIPHERAL BLOOD AS TOOL TO DETERMINE GENE EXPRESSION PATTERNS IN PATIENTS WITH PSYCHIATRIC, NEUROLOGICAL AND OTHER COMMON DISORDERS: A SYSTEMATIC REVIEW AND META-ANALYSIS PROTOCOL

D. Gelain, J. Moreira, C. Girardi, 2019 .

Chronic acrolein exposure in Wistar rats: The effects of guarana extracts

Diana C. Rostirolla, D. Gelain, J. Moreira, 2020 .

Aminochrome decreases NGF, GDNF and induces neuroinflammation in organotypic midbrain slice cultures

D. Gelain, J. Segura-Aguilar, C. S. Souza, 2018, Neurotoxicology.

Preventive supplementation with fresh and preserved peach attenuates CCl4-induced oxidative stress, inflammation and tissue damage.

D. Gelain, A. Zanotto-Filho, J. Moreira, 2014, The Journal of nutritional biochemistry.

Chronic retinyl palmitate supplementation to middle-aged Wistar rats disrupts the brain redox homeostasis and induces changes in emotional behavior.

D. Gelain, J. Moreira, F. Zeidán-Chuliá, 2015, Molecular nutrition & food research.

Evidence for the involvement of descending pain-inhibitory mechanisms in the attenuation of cancer pain by carvacrol aided through a docking study.

D. Gelain, M. Scotti, L. Scotti, 2014, Life sciences.

A longitudinal study of neurotrophic, oxidative, and inflammatory markers in first-onset depression in midlife women

M. Otto, L. Minuzzi, B. Frey, 2018, European Archives of Psychiatry and Clinical Neuroscience.

A statistical method to calculate blood contamination in the measurement of salivary hormones in healthy women.

B. Frey, D. Gelain, J. Moreira, 2017, Clinical biochemistry.

Effect of N-salicyloyltryptamine (STP), a novel tryptamine analogue, on parameters of cell viability, oxidative stress, and immunomodulation in RAW 264.7 macrophages

D. Gelain, J. Moreira, J. Barbosa-Filho, 2013, Cell Biology and Toxicology.

LPS leads to enhanced nuclear translocation of NF κ B and production of pro-infl ammatory cytokines [6,7]. NFkB is an inducible transcription factor that plays an essential role in the expression of a number of genes

I. J. Bristot, D. Gelain, J. Moreira, 2013 .

Coal and tire burning mixtures containing ultrafine and nanoparticulate materials induce oxidative stress and inflammatory activation in macrophages.

D. Gelain, J. Moreira, F. Caregnato, 2013, The Science of the total environment.

Cadmium stimulates MAPKs and Hsp27 phosphorylation in bovine adrenal chromaffin cells.

T. Posser, D. Gelain, C. Gonçalves, 2007, Toxicology.

Gastrin-Releasing Peptide Receptor Antagonism Induces Protection from Lethal Sepsis: Involvement of Toll-like Receptor 4 Signaling

R. Roesler, D. Gelain, A. Zanotto-Filho, 2012, Molecular medicine.

RAGE Against the Glycation Machine in Synucleinopathies: Time to Explore New Questions

D. Gelain, J. Moreira, T. Outeiro, 2023, Journal of Parkinson's disease.

Putative model for heat shock protein 70 complexation with receptor of advanced glycation end products through fluorescence proximity assays and normal mode analyses

R. Ligabue-Braun, D. Gelain, J. Moreira, 2016, Cell stress & chaperones (Print).

Curcumin Supplementation Decreases Intestinal Adiposity Accumulation, Serum Cholesterol Alterations, and Oxidative Stress in Ovariectomized Rats

D. Gelain, A. Zanotto-Filho, J. Moreira, 2015, Oxidative medicine and cellular longevity.

Guarana supplementation attenuated obesity, insulin resistance, and adipokines dysregulation induced by a standardized human Western diet via brown adipose tissue activation

R. Ligabue-Braun, D. Gelain, J. Moreira, 2019, Phytotherapy research : PTR.

Role of toll-like receptor 4 and sex in 6-hydroxydopamine–induced behavioral impairments and neurodegeneration in mice

D. Gelain, A. Zanotto-Filho, R. Prediger, 2021, Neurochemistry International.

Can electrons travel through actin microfilaments and generate oxidative stress in retinol treated Sertoli cell?

F. Klamt, C. Gottfried, D. Gelain, 2007, Molecular and Cellular Biochemistry.

NRF2 Mediates Neuroblastoma Proliferation and Resistance to Retinoic Acid Cytotoxicity in a Model of In Vitro Neuronal Differentiation

D. Gelain, A. Zanotto-Filho, J. Moreira, 2015, Molecular Neurobiology.

In vitro optimization of retinoic acid–induced neuritogenesis and TH endogenous expression in human SH-SY5Y neuroblastoma cells by the antioxidant Trolox

I. J. Bristot, F. Klamt, D. Gelain, 2011, Molecular and Cellular Biochemistry.

Oral administration of curcumin relieves behavioral alterations and oxidative stress in the frontal cortex, hippocampus, and striatum of ovariectomized Wistar rats.

D. Gelain, A. Zanotto-Filho, J. Moreira, 2016, The Journal of nutritional biochemistry.

The Janus Face of Resveratrol in Astroglial Cells

C. Gottfried, D. Gelain, J. Moreira, 2009, Neurotoxicity Research.

Increased tau phosphorylation and receptor for advanced glycation endproducts (RAGE) in the brain of mice infected with Leishmania amazonensis

Mario Roberto Senger, Felipe Dal-Pizzol, D. Gelain, 2015, Brain, Behavior, and Immunity.

Effects of chronic elevated ozone concentration on the redox state and fruit yield of red pepper plant Capsicum baccatum.

D. Gelain, J. Moreira, F. Reginatto, 2014, Ecotoxicology and environmental safety.

Neurochemical Research Retinol Effects Against 6-Hydroxydopamine-Induced Citotoxicity in SH-SY5Y Cells

D. Gelain, Jeferson Delgado, Alice Kunzler, 2018 .

Acute Administration of Branched-Chain Amino Acids Increases the Pro-BDNF/Total-BDNF Ratio in the Rat Brain

D. Gelain, J. Moreira, M. Bogo, 2015, Neurochemical Research.

Neurological impairment caused by Schistosoma mansoni systemic infection exhibits early features of idiopathic neurodegenerative disease

D. Gelain, F. Dal-Pizzol, H. Castro-Faria-Neto, 2021, The Journal of biological chemistry.

Immune neutralization of the receptor for advanced glycation end products reduce liver oxidative damage induced by an acute systemic injection of lipopolysaccharide

D. Gelain, J. Moreira, J. Gasparotto, 2018, Journal of biochemistry.

Is it all the RAGE? Defining the role of the receptor for advanced glycation end products in Parkinson's disease.

D. Gelain, J. Moreira, T. Outeiro, 2023, Journal of neurochemistry.

Increased alpha-synuclein and neuroinflammation in the substantia nigra triggered by systemic inflammation are reversed by targeted inhibition of the receptor for advanced glycation end products (RAGE).

D. Gelain, J. Gasparotto, C. Girardi, 2023, Journal of neurochemistry.

Retinol (Vitamin A) Increases α-Synuclein, β-Amyloid Peptide, Tau Phosphorylation and RAGE Content in Human SH-SY5Y Neuronal Cell Line

D. Gelain, J. Moreira, M. A. de Bittencourt Pasquali, 2017, Neurochemical Research.

Gastrin-Releasing Peptide Receptor Antagonism Induces Protection from Lethal Sepsis: Involvement of Toll-like Receptor 4 Signaling

R. Roesler, D. Gelain, A. Zanotto-Filho, 2012, Molecular medicine.

Anticancer activity of flavonoids isolated from Achyrocline satureioides in gliomas cell lines.

C. Klein, F. Figueiró, D. Gelain, 2018, Toxicology in vitro : an international journal published in association with BIBRA.

Redox characterization of usnic acid and its cytotoxic effect on human neuron-like cells (SH-SY5Y).

D. Gelain, J. Moreira, F. Zeidán-Chuliá, 2012, Toxicology in vitro : an international journal published in association with BIBRA.

Comparison between proliferative and neuron-like SH-SY5Y cells as an in vitro model for Parkinson disease studies

F. Klamt, D. Gelain, A. Zanotto-Filho, 2010, Brain Research.

Hydroethanolic extracts from different genotypes of açaí (Euterpe oleracea) presented antioxidant potential and protected human neuron-like cells (SH-SY5Y).

D. Gelain, J. Moreira, A. Jablonski, 2017, Food chemistry.

Turnera subulata Anti-Inflammatory Properties in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages.

D. Gelain, R. D. Albanus, M. A. de Bittencourt Pasquali, 2016, Journal of Medicinal Food.

Guarana (Paullinia cupana Mart.) Prevents β‐Amyloid Aggregation, Generation of Advanced Glycation‐end Products (AGEs), and Acrolein‐Induced Cytotoxicity on Human Neuronal‐Like Cells

D. Gelain, J. Moreira, F. Zeidán-Chuliá, 2014, Phytotherapy research : PTR.

Systemic Inflammation Changes the Site of RAGE Expression from Endothelial Cells to Neurons in Different Brain Areas

D. Gelain, J. Moreira, T. K. Rabelo, 2018, Molecular Neurobiology.

Coagulation biomarkers and coronavirus disease 2019 phenotyping: a prospective cohort study

D. Gelain, F. Dal-Pizzol, J. Moreira, 2023, Thrombosis Journal.

Transgenerational inheritance of methylmercury and vitamin A-induced toxicological effects in a Wistar rats environmental-based model.

D. Gelain, J. C. Fonseca Moreira, Pedro Ozorio Brum, 2024, Chemosphere.

Antinociceptive action and redox properties of citronellal, an essential oil present in lemongrass.

D. Gelain, J. Moreira, L. Bonjardim, 2011, Journal of medicinal food.

Sodium Propionate Oral Supplementation ameliorates Depressive-Like Behavior through Gut Microbiome and Histone 3 Epigenetic Regulation.

P. H. Rampelotto, D. Gelain, J. Gasparotto, 2024, The Journal of nutritional biochemistry.

Histone 3 Trimethylation Patterns are Associated with Resilience or Stress Susceptibility in a Rat Model of Major Depression Disorder.

D. Gelain, Pedro Ozorio Brum, Nauana Somensi, 2024, Molecular neurobiology.

Aging and neurodegeneration: From molecular mechanisms to therapeutic interventions.

D. Gelain, T. Outeiro, Patricia S. Brocardo, 2024, Journal of neurochemistry.

Biomarkers of methylmercury neurotoxicity and neurodevelopmental features: a systematic review.

D. Gelain, Alexsander Alves Teixeira, A. Panzenhagen, 2024, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.