A. Zanotto-Filho

发表

Retinol induces the ERK1/2-dependent phosphorylation of CREB through a pathway involving the generation of reactive oxygen species in cultured Sertoli cells.

I. Izquierdo, M. Cammarota, L. Bevilaqua, 2006, Cellular signalling.

ConBr lectin modulates MAPKs and Akt pathways and triggers autophagic glioma cell death by a mechanism dependent upon caspase-8 activation.

A. Zanotto-Filho, K. Nascimento, B. Cavada, 2020, Biochimie.

Scavenging and antioxidant potential of physiological taurine concentrations against different reactive oxygen/nitrogen species

F. Klamt, A. Zanotto-Filho, J. Moreira, 2010, Pharmacological reports : PR.

Changes in Cell Cycle and Up-Regulation of Neuronal Markers During SH-SY5Y Neurodifferentiation by Retinoic Acid are Mediated by Reactive Species Production and Oxidative Stress

Diana C. Rostirolla, D. Gelain, A. Zanotto-Filho, 2017, Molecular Neurobiology.

Efficient identification of novel anti-glioma lead compounds by machine learning models.

C. Andrade, A. Zanotto-Filho, B. J. Neves, 2019, European journal of medicinal chemistry.

CFL1 expression levels as a prognostic and drug resistance marker in nonsmall cell lung cancer

F. Klamt, E. Shacter, A. Zanotto-Filho, 2010, Cancer.

Proteasome inhibitor MG132 induces selective apoptosis in glioblastoma cells through inhibition of PI3K/Akt and NFkappaB pathways, mitochondrial dysfunction, and activation of p38-JNK1/2 signaling

A. Zanotto-Filho, J. Moreira, E. Braganhol, 2012, Investigational New Drugs.

The curry spice curcumin selectively inhibits cancer cells growth in vitro and in preclinical model of glioblastoma.

A. Zanotto-Filho, J. Moreira, R. Zanin, 2012, The Journal of nutritional biochemistry.

Retinol up-regulates the receptor for advanced glycation endproducts (RAGE) by increasing intracellular reactive species.

D. Gelain, A. Zanotto-Filho, J. Moreira, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

Xanthine oxidase-dependent ROS production mediates vitamin A pro-oxidant effects in cultured Sertoli cells

A. Zanotto-Filho, J. Moreira, R. Schröder, 2008, Free radical research.

Antioxidants improve oxaliplatin-induced peripheral neuropathy in tumor-bearing mice model: role of spinal cord oxidative stress and inflammation.

D. Gelain, A. Zanotto-Filho, J. Moreira, 2021, The journal of pain.

Extracellular HSP70 Activates ERK1/2, NF-kB and Pro-Inflammatory Gene Transcription Through Binding with RAGE in A549 Human Lung Cancer Cells

Diana C. Rostirolla, A. Zanotto-Filho, J. Moreira, 2017, Cellular Physiology and Biochemistry.

Boldine induces cell cycle arrest and apoptosis in T24 human bladder cancer cell line via regulation of ERK, AKT, and GSK-3β.

C. Barrios, F. Figueiró, A. Zanotto-Filho, 2014, Urologic oncology.

Chronic ozone exposure alters the secondary metabolite profile, antioxidant potential, anti-inflammatory property, and quality of red pepper fruit from Capsicum baccatum.

D. Gelain, A. Zanotto-Filho, J. Moreira, 2016, Ecotoxicology and environmental safety.

The NF kappa B-mediated control of RS and JNK signaling in vitamin A-treated cells: duration of JNK-AP-1 pathway activation may determine cell death or proliferation.

F. Klamt, D. Gelain, A. Zanotto-Filho, 2009, Biochemical pharmacology.

N-acetylcysteine and alpha-lipoic acid improve antioxidant defenses and decrease oxidative stress, inflammation and serum lipid levels in ovariectomized rats via estrogen-independent mechanisms.

E. B. Parisotto, A. Zamoner, A. Zanotto-Filho, 2019, The Journal of nutritional biochemistry.

Antioxidant Profile Characterization of a Commercial Paullinia cupana (Guarana) Extracts

D. Gelain, A. Zanotto-Filho, J. Moreira, 2016 .

Taurine prevents enhancement of acetylcholinesterase activity induced by acute ethanol exposure and decreases the level of markers of oxidative stress in zebrafish brain

F. Klamt, A. Zanotto-Filho, J. Moreira, 2010, Neuroscience.

Gastrin-releasing peptide receptor antagonist effects on an animal model of sepsis.

E. A. Bernard, R. Roesler, M. Cammarota, 2006, American journal of respiratory and critical care medicine.

Retinoic acid induces apoptosis by a non-classical mechanism of ERK1/2 activation.

M. Cammarota, D. Gelain, A. Zanotto-Filho, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

Retinol and retinoic acid modulate catalase activity in Sertoli cells by distinct and gene expression-independent mechanisms.

F. Klamt, D. Gelain, A. Zanotto-Filho, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

Retinol increases catalase activity and protein content by a reactive species-dependent mechanism in Sertoli cells.

F. Klamt, D. Gelain, A. Zanotto-Filho, 2008, Chemico-biological interactions.

Combined Gene Expression and RNAi Screening to Identify Alkylation Damage Survival Pathways from Fly to Human

U. Suresh, Yidong Chen, A. Zanotto-Filho, 2016, PloS one.

Potential of Total Polyphenols from Barbatimão against Different Reactive Oxygen/Nitrogen Species

W. L. Priamo, A. Zanotto-Filho, J. Moreira, 2015 .

Late autophagy inhibitor chloroquine improves efficacy of the histone deacetylase inhibitor SAHA and temozolomide in gliomas

A. Zanotto-Filho, J. Moreira, G. Lenz, 2019, Biochemical pharmacology.

Omics-based identification of an NRF2-related auranofin resistance signature in cancer: Insights into drug repurposing

M. Santos-Silva, A. Zanotto-Filho, N. Stefanes, 2022, Comput. Biol. Medicine.

Alkylating Agent–Induced NRF2 Blocks Endoplasmic Reticulum Stress–Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis

Yidong Chen, Xavier Bernard, A. Bishop, 2016, Molecular Cancer Therapeutics.

Aminonaphthoquinone induces oxidative stress in Staphylococcus aureus.

A. Zanotto-Filho, A. Brandelli, J. Henriques, 2006, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Sorafenib improves alkylating therapy by blocking induced inflammation, invasion and angiogenesis in breast cancer cells.

Yidong Chen, A. Bishop, A. Zanotto-Filho, 2018, Cancer letters.

Evaluation of antioxidant effect of extracts of Symphyopappus casarettoi.

A. Zanotto-Filho, J. Moreira, A. Coitinho, 2007, Fitoterapia.

Comparison between proliferative and neuron-like SH-SY5Y cells as an in vitro model for Parkinson disease studies

Fabio Klamt, Alfeu Zanotto-Filho, Flávio Kapczinski, 2010, Brain Research.

TLR4 expression and functionality are downregulated in glioblastoma cells and in tumor-associated macrophages: a new mechanism of immune evasion?

A. Zanotto-Filho, F. Visioli, T. Fazolo, 2021, Biochimica et biophysica acta. Molecular basis of disease.

NFκB inhibitors induce cell death in glioblastomas.

Alfeu Zanotto-Filho, Rodrigo J S Dalmolin, José Cláudio Fonseca Moreira, 2011, Biochemical pharmacology.

Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas.

I. J. Bristot, F. Figueiró, D. Gelain, 2015, Cancer letters.

Thioredoxin reductase-1 levels are associated with NRF2 pathway activation and tumor recurrence in non-small cell lung cancer.

D. Gelain, A. Zanotto-Filho, J. Moreira, 2021, Free radical biology & medicine.

Curcumin-loaded lipid-core nanocapsules as a strategy to improve pharmacological efficacy of curcumin in glioma treatment.

A. Zanotto-Filho, J. Moreira, S. Guterres, 2013, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

The lectin DrfL inhibits cell migration, adhesion and triggers autophagy-dependent cell death in glioma cells

A. Zanotto-Filho, K. Nascimento, B. Cavada, 2022, Glycoconjugate Journal.

Inflammatory landscape of human brain tumors reveals an NFκB dependent cytokine pathway associated with mesenchymal glioblastoma.

D. Gelain, A. Zanotto-Filho, J. Moreira, 2017, Cancer letters.

Embryonic Stem Cell-Related Protein L1TD1 Is Required for Cell Viability, Neurosphere Formation, and Chemoresistance in Medulloblastoma.

A. Zanotto-Filho, J. Moreira, O. Okamoto, 2015, Stem cells and development.

COX-2 promotes mammary adipose tissue inflammation, local estrogen biosynthesis, and carcinogenesis in high-sugar/fat diet treated mice.

D. Gelain, A. Zanotto-Filho, J. Moreira, 2021, Cancer letters.

BRCA-1 depletion impairs pro-inflammatory polarization and activation of RAW 264.7 macrophages in a NF-κB-dependent mechanism

F. Figueiró, D. Gelain, A. Zanotto-Filho, 2019, Molecular and Cellular Biochemistry.

Nucleotide receptors control IL-8/CXCL8 and MCP-1/CCL2 secretions as well as proliferation in human glioma cells.

A. Zanotto-Filho, J. Sévigny, F. Bahrami, 2015, Biochimica et biophysica acta.

The oxidation of HSP70 is associated with functional impairment and lack of stimulatory capacity

D. Gelain, A. Zanotto-Filho, J. Moreira, 2014, Cell Stress and Chaperones.

Supplementation with vitamin A enhances oxidative stress in the lungs of rats submitted to aerobic exercise.

C. Matté, D. Gelain, A. Zanotto-Filho, 2015, Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.

Retinol and retinoic acid increase MMP-2 activity by different pathways in cultured Sertoli cells

A. Zanotto-Filho, R. B. de Oliveira, J. Moreira, 2007, Free radical research.

The pharmacological NFkappaB inhibitors BAY117082 and MG132 induce cell arrest and apoptosis in leukemia cells through ROS-mitochondria pathway activation.

F. Klamt, A. Zanotto-Filho, J. Moreira, 2010, Cancer letters.

The oxidation of HSP70 is associated with functional impairment and lack of stimulatory capacity

D. Gelain, A. Zanotto-Filho, J. Moreira, 2014, Cell Stress and Chaperones.

Preventive supplementation with fresh and preserved peach attenuates CCl4-induced oxidative stress, inflammation and tissue damage.

D. Gelain, A. Zanotto-Filho, J. Moreira, 2014, The Journal of nutritional biochemistry.

Lectin from Dioclea violacea induces autophagy in U87 glioma cells.

A. Zanotto-Filho, K. Nascimento, B. Cavada, 2019, International journal of biological macromolecules.

Resveratrol-loaded lipid-core nanocapsules treatment reduces in vitro and in vivo glioma growth.

F. Figueiró, A. Zanotto-Filho, J. Moreira, 2013, Journal of biomedical nanotechnology.

Differential effects of retinol and retinoic acid on cell proliferation: A role for reactive species and redox-dependent mechanisms in retinol supplementation

A. Zanotto-Filho, J. Moreira, R. Schröder, 2008, Free radical research.

The role of two putative nitroreductases, Frm2p and Hbn1p, in the oxidative stress response in Saccharomyces cerevisiae

D. Bonatto, A. Zanotto-Filho, J. Moreira, 2009, Yeast.

Gastrin-Releasing Peptide Receptor Antagonism Induces Protection from Lethal Sepsis: Involvement of Toll-like Receptor 4 Signaling

R. Roesler, D. Gelain, A. Zanotto-Filho, 2012, Molecular medicine.

Curcumin Supplementation Decreases Intestinal Adiposity Accumulation, Serum Cholesterol Alterations, and Oxidative Stress in Ovariectomized Rats

D. Gelain, A. Zanotto-Filho, J. Moreira, 2015, Oxidative medicine and cellular longevity.

Role of toll-like receptor 4 and sex in 6-hydroxydopamine–induced behavioral impairments and neurodegeneration in mice

D. Gelain, A. Zanotto-Filho, R. Prediger, 2021, Neurochemistry International.

Classification algorithms applied to blood-based transcriptome meta-analysis to predict idiopathic Parkinson's disease

Marcelo Falchetti, Rui Daniel Prediger, Alfeu Zanotto-Filho, 2020, Comput. Biol. Medicine.

Antioxidant activities and free radical scavenging potential of Bauhinia microstachya (RADDI) MACBR. (Caesalpinaceae) extracts linked to their polyphenol content.

A. Zanotto-Filho, F. Dal-Pizzol, J. Moreira, 2007, Biological & pharmaceutical bulletin.

NRF2 Mediates Neuroblastoma Proliferation and Resistance to Retinoic Acid Cytotoxicity in a Model of In Vitro Neuronal Differentiation

D. Gelain, A. Zanotto-Filho, J. Moreira, 2015, Molecular Neurobiology.

In vitro optimization of retinoic acid–induced neuritogenesis and TH endogenous expression in human SH-SY5Y neuroblastoma cells by the antioxidant Trolox

I. J. Bristot, F. Klamt, D. Gelain, 2011, Molecular and Cellular Biochemistry.

Oral administration of curcumin relieves behavioral alterations and oxidative stress in the frontal cortex, hippocampus, and striatum of ovariectomized Wistar rats.

D. Gelain, A. Zanotto-Filho, J. Moreira, 2016, The Journal of nutritional biochemistry.

DNA-PKcs restricts Zika virus spreading and is required for effective antiviral response

A. Zanotto-Filho, L. Granella, D. Mansur, 2022, Frontiers in Immunology.

NFκB pathway analysis: An approach to analyze gene co-expression networks employing feedback cycles

Luigi Carro, Fabiane Cristine Dillenburg, Leila Ribeiro, 2017, Comput. Biol. Chem..

Reduced serum non-enzymatic antioxidant defense and increased lipid peroxidation in schizophrenic patients on a hypocaloric diet

A. Zanotto-Filho, J. Moreira, P. Belmonte-de-Abreu, 2012, Neuroscience Letters.

Gastrin-Releasing Peptide Receptor Antagonism Induces Protection from Lethal Sepsis: Involvement of Toll-like Receptor 4 Signaling

R. Roesler, D. Gelain, A. Zanotto-Filho, 2012, Molecular medicine.

The curry spice curcumin selectively inhibits cancer cells growth in vitro and in preclinical model of glioblastoma.

A. Zanotto-Filho, J. Moreira, R. Zanin, 2012, The Journal of nutritional biochemistry.

Comparison between proliferative and neuron-like SH-SY5Y cells as an in vitro model for Parkinson disease studies

F. Klamt, D. Gelain, A. Zanotto-Filho, 2010, Brain Research.

Sorafenib improves alkylating therapy by blocking induced inflammation, invasion and angiogenesis in breast cancer cells.

Yidong Chen, A. Zanotto-Filho, V. Masamsetti, 2018, Cancer letters.

CFL1 expression levels as a prognostic and drug resistance marker in nonsmall cell lung cancer

F. Klamt, E. Shacter, A. Zanotto-Filho, 2010, Cancer.

β-Caryophyllene Inhibits Oxaliplatin-Induced Peripheral Neuropathy in Mice: Role of Cannabinoid Type 2 Receptors, Oxidative Stress and Neuroinflammation

A. Zanotto-Filho, J. R. Santin, Jonathan Paulo Agnes, 2023, Antioxidants.

The pharmacological NFkappaB inhibitors BAY117082 and MG132 induce cell arrest and apoptosis in leukemia cells through ROS-mitochondria pathway activation.

F. Klamt, A. Zanotto-Filho, J. Moreira, 2010, Cancer letters.

N-(2-hydroxyl)propyl-3-trimethyl ammonium chitosan-coated gold nanoparticle-based platform for photothermal/ chemo-photodynamic therapy

A. Zanotto-Filho, Adriana P. Gerola, Patrícia Sangaletti, 2024, Journal of Molecular Liquids.