K. Higuchi

发表

COX-2 Is Essential for EGF Induction of Cell Proliferation in Gastric RGM1 Cells

A. Tarnawski, E. Sasaki, K. Tominaga, 2003, Digestive Diseases and Sciences.

Clinical features and therapeutic responses to proton pump inhibitor in patients with severe reflux esophagitis: A multicenter prospective observational study

K. Haruma, T. Joh, K. Higuchi, 2020, JGH open : an open access journal of gastroenterology and hepatology.

A diagnosis support system for capsule endoscopy

R. Sagawa, Y. Yagi, Y. Yagi, 2007, Inflammopharmacology.

In vivo trial of a driving system for a self-propelling capsule endoscope using a magnetic field (with video).

K. Higuchi, E. Morita, N. Ohtsuka, 2010, Gastrointestinal endoscopy.

Comparison of teprenone and famotidine against gastroduodenal mucosal damage in patients taking low‐dose aspirin

Takuya Inoue, Takeshi Azuma, Kazuhide Higuchi, 2014, Journal of gastroenterology and hepatology.

Guidelines for standardizing cleansing and disinfection of gastrointestinal endoscopes

T. Ohtsuka, H. Tajiri, T. Gotoda, 2019, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Autophagy Deficiency Diminishes Indomethacin-Induced Intestinal Epithelial Cell Damage through Activation of the ERK/Nrf2/HO-1 Pathway

K. Higuchi, T. Nakagawa, Takuya Inoue, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2015

K. Sugano, T. Kawano, M. Hongo, 2016, Journal of Gastroenterology.

Roles of epidermal growth factor and Na+/H+ exchanger-1 in esophageal epithelial defense against acid-induced injury.

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2006, American journal of physiology. Gastrointestinal and liver physiology.

Association Between Dinner-to-Bed Time and Gastro-Esophageal Reflux Disease

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2005, The American Journal of Gastroenterology.

Differences in Clinical Characteristics between Patients with Endoscopy-Negative Reflux Disease and Erosive Esophagitis in Japan

E. Sasaki, K. Tominaga, Toshio Watanabe, 2005, The American Journal of Gastroenterology.

Association between gastroesophageal flap valve, reflux esophagitis, Barrett's epithelium, and atrophic gastritis assessed by endoscopy in Japanese patients

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2003, Journal of Gastroenterology.

Small-intestinal hemorrhage caused by treatment with sorafenib for hepatocellular carcinoma and diagnosed by capsule endoscopy

K. Higuchi, T. Nishikawa, S. Nouda, 2013, Endoscopy.

The Super-Kamiokande detector

B. Viren, L. R. Sulak, M. Malek, 2003 .

Roles of cyclooxygenase 2 and microsomal prostaglandin E synthase 1 in rat acid reflux oesophagitis

E. Sasaki, K. Tominaga, Y. Fujiwara, 2005, Gut.

Safety and Efficacy of Laparoscopic Liver Resection for Colorectal Liver Metastasis With Obesity

K. Higuchi, K. Uchiyama, A. Asai, 2020, The American surgeon.

Preventive effect of ecabet sodium on low-dose aspirin-induced small intestinal mucosal injury: a randomized, double-blind, pilot study

K. Higuchi, S. Nouda, T. Kuramoto, 2019, BMC Gastroenterology.

Determination of the adequate dosage of rebamipide, a gastric mucoprotective drug, to prevent low-dose aspirin-induced gastrointestinal mucosal injury

K. Higuchi, S. Nouda, T. Kuramoto, 2016, Journal of clinical biochemistry and nutrition.

Role of neutrophils in a rat model of gastric ulcer recurrence caused by interleukin-1 beta.

Toshio Watanabe, K. Higuchi, T. Arakawa, 1997, The American journal of pathology.

Liver abscess caused by CTX-M-55-type extended-spectrum β-lactamase (ESBL)-producing Salmonella enteritidis.

K. Higuchi, A. Ukimura, Y. Ooi, 2014, Internal medicine.

Relevance of the Core 70 and IL-28B polymorphism and response-guided therapy of peginterferon alfa-2a ± ribavirin for chronic hepatitis C of Genotype 1b: a multicenter randomized trial, ReGIT-J study

M. Kudo, N. Nishida, K. Okazaki, 2013, Journal of Gastroenterology.

Neutrino-induced upward stopping muons in Super-Kamiokande

Minoru Yoshida, S. Kim, E. Blaufuss, 1999 .

PPAR-gamma ligands inhibit growth of human esophageal adenocarcinoma cells through induction of apoptosis, cell cycle arrest and reduction of ornithine decarboxylase activity.

Y. Fujiwara, K. Higuchi, T. Arakawa, 2001, International journal of oncology.

Endoscopic Diagnosis of the Invasion Depth of T1 Colorectal Carcinoma for Endoscopic Resection by Using Narrow-Band Imaging Magnification as Total Excisional Biopsy

K. Higuchi, Shinji Tanaka, S. Fukunishi, 2016, Digestion.

Indomethacin-induced intestinal epithelial cell damage is mediated by pVHL activation through the degradation of collagen I and HIF-1α.

K. Higuchi, T. Nakagawa, Y. Kojima, 2015, Biochemical and biophysical research communications.

Recurrent Peptic Ulcers in Patients Following Successful Helicobacter pylori Eradication: A Multicenter Study of 4940 Patients

K. Sugano, T. Ohkusa, K. Haruma, 2004, Helicobacter.

Validity of endoscopic classification of nonerosive reflux disease

M. Hongo, T. Joh, T. Chiba, 2007, Journal of Gastroenterology.

Long-term efficacy and safety of rabeprazole in patients taking low-dose aspirin with a history of peptic ulcers: a phase 2/3, randomized, parallel-group, multicenter, extension clinical trial

Mototsugu Kato, M. Fujishiro, Toshio Watanabe, 2015, Journal of clinical biochemistry and nutrition.

Laparoscopic and endoscopic cooperative surgery for intra-mucosal gastric carcinoma adjacent to the ulcer scars

K. Higuchi, T. Takeuchi, M. Aoki, 2018, World Journal of Surgical Oncology.

A long-lasting dipeptidyl peptidase-4 inhibitor, teneligliptin, as a preventive drug for the development of hepatic steatosis in high-fructose diet-fed ob/ob mice.

K. Higuchi, A. Asai, S. Fukunishi, 2017, International journal of molecular medicine.

The Relationship Between Postoperative Chemotherapy and Remnant Liver Regeneration and Outcomes After Hepatectomy for Colorectal Liver Metastasis

K. Higuchi, K. Uchiyama, A. Asai, 2018, Journal of Gastrointestinal Surgery.

Retrospective Study as First-Line Chemotherapy Combined Anti-VEGF Antibody with Fluoropyrimidine for Frail Patients with Unresectable or Metastatic Colorectal Cancer

K. Higuchi, T. Kii, M. Goto, 2013, Digestion.

Impact of modified FOLFOX‐6 for patients with gastric cancer and a gastrointestinal obstruction

K. Higuchi, T. Kii, M. Aoki, 2018, Asia-Pacific journal of clinical oncology.

Pharyngeal observation via transoral endoscopy using a lip cover‐type mouthpiece

N. Uedo, K. Higashino, R. Ishihara, 2019, Journal of Gastroenterology and Hepatology.

Guidelines for gastroenterological endoscopy in patients undergoing antithrombotic treatment

T. Matsui, K. Murakami, Mototsugu Kato, 2014, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Volumetric and Functional Regeneration of Remnant Liver after Hepatectomy

K. Higuchi, K. Uchiyama, A. Asai, 2018, Journal of Gastrointestinal Surgery.

Reduction of 15‐hydroxyprostaglandin dehydrogenase expression is an independent predictor of poor survival associated with enhanced cell proliferation in gastric adenocarcinoma

T. Sawada, K. Tominaga, Toshio Watanabe, 2010, Cancer science.

Massive Ascites Caused by Primary Diffuse Large B-cell Lymphoma of the Jejunum: A Case of a Rare Initial Symptom

K. Higuchi, Taro Iwatsubo, T. Takeuchi, 2020, Internal medicine.

Development of a New Contrast Endoscopic Method with Techno Color Blue P

K. Higuchi, E. Umegaki, T. Takeuchi, 2009 .

The Relationship Between the Number of Ports and Surgical Outcomes in Laparoscopic Hepatectomy

K. Higuchi, K. Uchiyama, A. Asai, 2019, Surgical laparoscopy, endoscopy & percutaneous techniques.

Laparoscopic Repeat Hepatic Resection for the Management of Liver Tumors

K. Higuchi, K. Uchiyama, A. Asai, 2019, Journal of Gastrointestinal Surgery.

The utility of the subcuticular suture in hepatic resection

K. Higuchi, K. Uchiyama, A. Asai, 2018, Contemporary oncology.

Comparison of resection site of standardized laparoscopic hepatic tumor resection

K. Higuchi, K. Uchiyama, A. Asai, 2018, Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques.

The role of advanced endoscopy in the management of inflammatory digestive diseases (upper gastrointestinal tract)

Mototsugu Kato, Y. Fujiwara, K. Higuchi, 2021, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Risk Factors for Nephrotoxicity due to Tacrolimus Therapy for Ulcerative Colitis

K. Higuchi, Y. Tatsumi, Takuya Inoue, 2022, Digestion.

Effects of Chronic Kidney Disease on Outcomes of Hepatic Resection

K. Higuchi, K. Uchiyama, A. Asai, 2020, Journal of Gastrointestinal Surgery.

Simvastatin Attenuates Intestinal Fibrosis Independent of the Anti-Inflammatory Effect by Promoting Fibroblast/Myofibroblast Apoptosis in the Regeneration/Healing Process from TNBS-Induced Colitis

K. Higuchi, E. Morita, T. Kuramoto, 2012, Digestive Diseases and Sciences.

Anti-Inflammatory Effects of Pravastatin on Helicobacter Pylori-Induced Gastritis in Mice

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2007, Digestive Diseases and Sciences.

Retrograde colon capsule endoscopy with the self‐propelling capsule endoscope: The first human trial (with videos)

K. Higuchi, S. Nouda, K. Ota, 2018, Digestive Endoscopy.

Evidence-based clinical practice guidelines for functional dyspepsia

K. Sugano, M. Hongo, K. Haruma, 2015, Journal of Gastroenterology.

Lipopolysaccharides accelerate hepatic steatosis in the development of nonalcoholic fatty liver disease in Zucker rats

K. Higuchi, A. Asai, S. Fukunishi, 2013, Journal of clinical biochemistry and nutrition.

Association between UGT1A1 gene polymorphism and safety and efficacy of irinotecan monotherapy as the third-line treatment for advanced gastric cancer

K. Higuchi, Ken Kato, T. Hamaguchi, 2019, Gastric Cancer.

Safety and Efficacy of S-1, a Novel Oral Fluorouracil Antitumor Drug, for a Chronic Renal Failure Patient Maintained on Hemodialysis

E. Sasaki, K. Tominaga, Toshio Watanabe, 2004, Oncology.

The Capsule Endoscopy Findings in S-1-induced Enteritis with Severe Diarrhea during Adjuvant Chemotherapy for Gastric Cancer (with Video)

K. Higuchi, S. Nouda, T. Takeuchi, 2017, Internal medicine.

Extremely minimal neuroendocrine tumor of the pancreas with stenosis of main pancreatic duct

K. Higuchi, K. Uchiyama, E. Umegaki, 2012 .

Small-cell Lung Cancer in a Young Adult Nonsmoking Patient with Ectopic Adrenocorticotropin (ACTH) Production.

K. Higuchi, Y. Fujisaka, Yosuke Tamura, 2016, Internal medicine.

Successful treatment with topical mesalazine for a patient with intractable crohn’s colitis

N. Oshitani, K. Higuchi, T. Arakawa, 2002 .

Type of second primary malignancy after achieving complete response by definitive chemoradiation therapy in patients with esophageal squamous cell carcinoma

J. Itami, K. Higuchi, Ken Kato, 2018, International Journal of Clinical Oncology.

Efficacy and Safety of Helicobacter pylori Eradication Therapy with Omeprazole, Amoxicillin and High- and Low-Dose Clarithromycin in Japanese Patients

K. Higuchi, T. Arakawa, C. Sakamoto, 2006, Clinical drug investigation.

Eradication of Helicobacter pylori With a Chinese Herbal Medicine Without Emergence of Resistant Colonies

Y. Fujiwara, K. Higuchi, T. Arakawa, 1999, American Journal of Gastroenterology.

Indomethacin can induce cell death in rat gastric parietal cells through alteration of some apoptosis‐ and autophagy‐associated molecules

Yuko Ito, K. Higuchi, M. Shibata, 2020, International journal of experimental pathology.

Metabolic Syndrome and Sarcopenia

K. Higuchi, A. Asai, S. Nishiguchi, 2021, Nutrients.

Marked Enhancement by Fish Meal of Helicobacter pylori‐induced Gastritis in Mongolian Gerbils

T. Sugimura, K. Wakabayashi, K. Higuchi, 2000, Japanese journal of cancer research : Gann.

Prevalence of gastroesophageal reflux disease and gastroesophageal reflux disease symptoms in Japan

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2005, Journal of gastroenterology and hepatology.

The Relationship between the SARC-F Score and the Controlling Nutritional Status Score in Gastrointestinal Diseases

K. Higuchi, A. Asai, T. Takeuchi, 2022, Journal of clinical medicine.

Grip Strength in Patients with Gastrointestinal Diseases

K. Higuchi, A. Asai, T. Takeuchi, 2022, Journal of clinical medicine.

The Relevance in the Neutrophil to Lymphocyte Ratio and the SARC-F Score in Gastrointestinal Diseases

K. Higuchi, A. Asai, T. Takeuchi, 2022, Journal of clinical medicine.

Prognostic Impact of the SARC-F Score in Gastrointestinal Advanced Cancers

K. Higuchi, A. Asai, T. Takeuchi, 2021, Cancers.

Comparison of SARC-F Score among Gastrointestinal Diseases

K. Higuchi, A. Asai, T. Takeuchi, 2021, Journal of clinical medicine.

Inflammatory Bowel Disease and Sarcopenia: Its Mechanism and Clinical Importance

K. Higuchi, A. Asai, S. Nishiguchi, 2021, Journal of clinical medicine.

Cancer Cachexia: Its Mechanism and Clinical Significance

K. Higuchi, A. Asai, S. Nishiguchi, 2021, International journal of molecular sciences.

R-etodolac induces E-cadherin and suppresses colitis-related mouse colon tumorigenesis.

K. Higuchi, E. Morita, T. Kuramoto, 2010, Oncology reports.

Long-term use of nonsteroidal anti-inflammatory drugs normalizes the kinetics of gastric epithelial cells in patients with Helicobacter pylori infection via attenuation of gastric mucosal inflammation

A. Tarnawski, K. Tominaga, Toshio Watanabe, 2009, Journal of Gastroenterology.

Regression of primary low-grade mucosa-associated lymphoid tissue lymphoma of duodenum after long-term treatment with clarithromycin

E. Sasaki, K. Tominaga, Toshio Watanabe, 2006, Scandinavian journal of gastroenterology.

Increased expression of epidermal growth factor receptors in basal cell hyperplasia of the oesophagus after acid reflux oesophagitis in rats

K. Tominaga, Y. Fujiwara, N. Oshitani, 2002, Alimentary pharmacology & therapeutics.

Platelet recovery after eradication of Helicobacter pylori in patients with idiopathic thrombocytopenic purpura

M. Hino, T. Yamane, K. Ohta, 2002, Annals of Hematology.

Efficacy and safety of laparoscopic hepatectomy for hepatocellular carcinoma comorbid with cirrhosis

K. Higuchi, K. Uchiyama, A. Asai, 2020, Przeglad gastroenterologiczny.

The Effects of Allogeneic Blood Transfusion in Hepatic Resection

K. Higuchi, K. Uchiyama, A. Asai, 2020, The American surgeon.

The Management of Recurrence within Six Months after Hepatic Resection for Colorectal Liver Metastasis

K. Higuchi, K. Uchiyama, A. Asai, 2019, Digestive Surgery.

Laparoscopic liver resection for patients with cardiac disease

K. Higuchi, K. Uchiyama, A. Asai, 2019, Contemporary oncology.

CLINICAL EVALUATION OF BLEEDING AFTER ENDOSCOPIC VARICEAL LIGATION

N. Suzuki, K. Higuchi, T. Arakawa, 1996 .

Serum zinc value in patients with hepatitis virus-related chronic liver disease: association with the histological degree of liver fibrosis and with the severity of varices in compensated cirrhosis

K. Higuchi, H. Imanishi, H. Iijima, 2014, Journal of clinical biochemistry and nutrition.

What are the risk factors for aggravation of esophageal varices in patients with hepatocellular carcinoma?

E. Sasaki, K. Tominaga, Toshio Watanabe, 2007, Journal of gastroenterology and hepatology.

Endoscopic gallbladder drainage for acute cholecystitis with high-risk surgical patients between transduodenal and transpapillary stenting

S. Ueno, K. Higuchi, T. Ogura, 2021, Endoscopic ultrasound.

Risk factors for adverse events associated with bile leak during EUS-guided hepaticogastrostomy

S. Ueno, K. Higuchi, T. Ogura, 2020, Endoscopic ultrasound.

Utility and problems of endoscopic submucosal dissection for early gastric cancer in elderly patients

K. Higuchi, M. Murano, E. Umegaki, 2012, Journal of gastroenterology and hepatology.

Exploratory Study of the Effectiveness of Granulocyte and Monocyte Adsorptive Apheresis Before Initiation of Steroids in Patients With Active Ulcerative Colitis (EXPECT Study): A Multicenter Prospective Clinical Trial

K. Higuchi, N. Aoyama, N. Kamata, 2020, Crohn's & colitis 360.

Small Intestinal Lesions in Patients with Anemia on Hemodialysis: A Two-Center, Cross-Sectional Study

K. Higuchi, T. Takeuchi, K. Ota, 2019, Digestion.

S. Ng, Justin C.Y. Wu, F. Chan, 2017, Gastroenterology.

Randomised clinical trial: prevention of recurrence of peptic ulcers by rabeprazole in patients taking low‐dose aspirin

M. Fujishiro, K. Higuchi, T. Arakawa, 2014, Alimentary pharmacology & therapeutics.

Inhibition by 16,16-Dimethyl Prostaglandin E2 of Tumor Necrosis Factor-α and Interleukin-1β Production and Messenger RNA Expression in Human Monocytes Stimulated by Helicobacter pylori

Y. Fujiwara, K. Higuchi, T. Arakawa, 1999, Digestive Diseases and Sciences.

Monocyte chemotactic protein-1 regulates leukocyte recruitment during gastric ulcer recurrence induced by tumor necrosis factor-α

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2004 .

Increased Expression of Cytokines and Adhesion Molecules in Rat Chronic Esophagitis

E. Sasaki, K. Tominaga, Toshio Watanabe, 2004, Digestion.

Comparison of the effects of rebamipide with those of cimetidine on chronic gastritis associated with Helicobacter pylori in Mongolian gerbils

E. Sasaki, K. Tominaga, Y. Fujiwara, 2003, Alimentary pharmacology & therapeutics.

Acid regulates inflammatory response in a rat model of induction of gastric ulcer recurrence by interleukin 1β

K. Tominaga, Y. Fujiwara, K. Higuchi, 2001, Gut.

Induction of signal transduction pathways in rat gastric epithelial cells stimulated with interleukin‐1β

Shokei Kim, H. Iwao, K. Tominaga, 2000 .

Recommendation of a newly developed slit-and-hole-type elastic hood for detection of more colon polyps

K. Higuchi, Takuya Inoue, M. Murano, 2008, Journal of Gastroenterology.

CASE REPORT: Esophagogastric Varices Due to Arterioportal Shunt in a Serous Cystadenoma of the Pancreas in von Hippel-Lindau Disease

A. Tamori, K. Wakasa, T. Shuin, 2003, Digestive Diseases and Sciences.

An immunosuppressive subtype of neutrophils identified in patients with hepatocellular carcinoma

K. Higuchi, A. Asai, S. Fukunishi, 2012, Journal of clinical biochemistry and nutrition.

Long-term feeding of a synthetic diet rich in disaccharides induces hepatic fibrosis in nonalcoholic fatty liver disease in Zucker rats.

T. Hanafusa, H. Nishio, Koichi Suzuki, 2009, International journal of molecular medicine.

Exacerbation of liver dysfunction in non-alcoholic steatohepatitis patients during the coronavirus disease 2019 (COVID-19) pandemic

K. Higuchi, A. Asai, S. Fukunishi, 2020, Journal of clinical biochemistry and nutrition.

Anti-inflammatory effect of two isoforms of COX in H. pylori-induced gastritis in mice: possible involvement of PGE2.

E. Sasaki, K. Tominaga, Toshio Watanabe, 2004, American journal of physiology. Gastrointestinal and liver physiology.

Neural invasion induces cachexia via astrocytic activation of neural route in pancreatic cancer

A. Ochiai, M. Ikeda, K. Higuchi, 2012, International journal of cancer.

The production of interferon-γ-inducible protein 10 by granulocytes and monocytes is associated with ulcerative colitis disease activity

Y. Fujiwara, N. Oshitani, K. Higuchi, 2007, Journal of Gastroenterology.

Leptin Promotes Gastric Ulcer Healing via Upregulation of Vascular Endothelial Growth Factor

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2010, Digestion.

Development of Fibrosis in Nonalcoholic Steatosis through Combination of a Synthetic Diet Rich in Disaccharide and Low-Dose Lipopolysaccharides in the Livers of Zucker (fa/fa) Rats

T. Hanafusa, H. Nishio, Koichi Suzuki, 2009, Journal of clinical biochemistry and nutrition.

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of High-Dose Rebamipide Treatment for Low-Dose Aspirin-Induced Moderate-to-Severe Small Intestinal Damage

Y. Naito, T. Yoshikawa, Toshio Watanabe, 2015, PloS one.

Correlation of MAP kinases with COX‐2 induction differs between MKN45 and HT29 cells

H. Iwao, E. Sasaki, K. Tominaga, 2004, Alimentary pharmacology & therapeutics.

Sitagliptin can inhibit the development of hepatic steatosis in high-fructose diet-fed ob/ob mice

K. Higuchi, A. Asai, Masaaki Ii, 2015, Journal of clinical biochemistry and nutrition.

Prostaglandins in the stomach: an update.

Y. Fujiwara, K. Higuchi, T. Arakawa, 1998, Journal of clinical gastroenterology.

Clinical efficacy and safety of endoscopic ultrasound‐guided gallbladder drainage replacement of percutaneous drainage: A multicenter retrospective study

M. Kudo, Tomohiro Watanabe, M. Takenaka, 2018, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Epiregulin stimulates proliferation of rabbit gastric cells in primary culture through autophosphorylation of the epidermal growth factor receptor.

E. Sasaki, Y. Fujiwara, K. Higuchi, 1997, European journal of pharmacology.

Ileal Bile Acid Transporter Inhibitor Improves Hepatic Steatosis by Ameliorating Gut Microbiota Dysbiosis in NAFLD Model Mice

K. Higuchi, T. Nakano, A. Asai, 2021, mBio.

Regenerative Therapy for Liver Cirrhosis Based on Intrahepatic Arterial Infusion of Autologous Subcutaneous Adipose Tissue-Derived Regenerative (Stem) Cells: Protocol for a Confirmatory Multicenter Uncontrolled Clinical Trial

M. Honda, S. Kaneko, K. Harada, 2020, JMIR research protocols.

Ileal bile acid transporter inhibitor improves hepatic steatosis by changing the gut microbiota dysbiosis in NAFLD model mice

T. Nakano, K. Higuchi, A. Asai, 2020 .

Dipeptidyl peptidase IV inhibition potentiates amino acid- and bile acid-induced bicarbonate secretion in rat duodenum.

K. Higuchi, J. Kaunitz, Takuya Inoue, 2012, American journal of physiology. Gastrointestinal and liver physiology.

M2b Monocytes Provoke Bacterial Pneumonia and Gut Bacteria–Associated Sepsis in Alcoholics

Sumihiro Suzuki, Makiko Kobayashi, K. Higuchi, 2015, The Journal of Immunology.

Risk factors and prediction of bleeding after gastric endoscopic submucosal dissection in patients on antithrombotic therapy: newly developed bleeding prediction application software, SAMURAI model

K. Murakami, Y. Naito, N. Yoshida, 2021, Journal of clinical biochemistry and nutrition.

Intermittent fasting prompted recovery from dextran sulfate sodium-induced colitis in mice

K. Higuchi, S. Fukuda, Takuya Inoue, 2017, Journal of clinical biochemistry and nutrition.

Indomethacin suppresses LAMP-2 expression and induces lipophagy and lipoapoptosis in rat enterocytes via the ER stress pathway

Yuko Ito, K. Higuchi, Takuya Inoue, 2015, Journal of Gastroenterology.

Long-term prospective pilot study with tranilast for the prevention of stricture progression in patients with Crohn’s disease

N. Oshitani, K. Higuchi, T. Arakawa, 2007, Gut.

Roles of cyclooxygenase-2 and prostaglandin E receptors in gastric mucosal defense in Helicobacter pylori-infected mice

K. Tominaga, Y. Fujiwara, N. Oshitani, 2007, Inflammopharmacology.

Overexpression of co-stimulatory molecules in peripheral mononuclear cells of Helicobacter pylori- positive peptic ulcer patients: possible difference in host responsiveness compared with non-ulcer patients

K. Higuchi, T. Arakawa, K. Kaneda, 2001, European journal of gastroenterology & hepatology.

The Super-Kamiokande Collaboration

E. Blaufuss, G. Sullivan, M. Takita, 1999 .

Dipeptidyl Peptidase IV Inhibition Prevents the Formation and Promotes the Healing of Indomethacin-Induced Intestinal Ulcers in Rats

K. Higuchi, J. Kaunitz, I. Kaji, 2014, Digestive Diseases and Sciences.

CD34+CD10+CD19− Cells in Patients with Unhealthy Alcohol Use Stimulate the M2b Monocyte Polarization

K. Higuchi, A. Chopra, A. Asai, 2022, Cells.

Hepatic F4/80+CD11b+CD68– cells influence the antibacterial response in irradiated mice with sepsis by Enterococcus faecalis

K. Higuchi, A. Asai, S. Fukunishi, 2021, Journal of leukocyte biology.

Short-Term Alcohol Abstinence Improves Antibacterial Defenses of Chronic Alcohol-Consuming Mice against Gut Bacteria-Associated Sepsis Caused by Enterococcus faecalis Oral Infection.

Sumihiro Suzuki, Makiko Kobayashi, K. Higuchi, 2017, The American journal of pathology.

Consuming Mice against Gut Bacteria e Associated Sepsis Caused by Enterococcus faecalis Oral Infection

Sumihiro Suzuki, Makiko Kobayashi, K. Higuchi, 2017 .

Pathophysiology and mechanisms of primary sarcopenia (Review).

K. Higuchi, A. Asai, S. Nishiguchi, 2021, International journal of molecular medicine.

Pharmacokinetics of Dexamethasone when Administered with Fosaprepitant for Chemotherapy-Induced Nausea and Vomiting and Differences in Dose-Dependent Antiemetic Effects

K. Higuchi, M. Goto, T. Terazawa, 2021, Asian Pacific journal of cancer prevention : APJCP.

A novel rat model to determine interaction between reflux oesophagitis and bronchial asthma

K. Tominaga, Y. Fujiwara, N. Oshitani, 2008, Gut.

Effect of chronic stress on gastric emptying and plasma ghrelin levels in rats.

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2008, Life sciences.

Cost-utility analysis of a ‘vonoprazan-first’ strategy versus ‘esomeprazole- or rabeprazole-first’ strategy in GERD

K. Higuchi, T. Takeuchi, A. Igarashi, 2019, Journal of Gastroenterology.

Successful treatment of giant rectal varices by modified percutaneous transhepatic obliteration with sclerosant: Report of a case.

A. Tamori, K. Tominaga, Toshio Watanabe, 2006, World journal of gastroenterology.

Randomised clinical trial: rabeprazole improves symptoms in patients with functional dyspepsia in Japan

M. Hongo, K. Haruma, K. Tominaga, 2013, Alimentary pharmacology & therapeutics.

Plummer–Vinson syndrome successfully treated by endoscopic dilatation

H. Kinoshita, K. Tominaga, Toshio Watanabe, 2007, Journal of gastroenterology and hepatology.

Letter to the EditorResponse

K. Higuchi, K. Hara, K. Yamao, 2012 .

Fatty acids in a high-fat diet potentially induce gastric parietal-cell damage and metaplasia in mice

K. Higuchi, S. Fukuda, Takamasa Ishikawa, 2017, Journal of Gastroenterology.

Subacute Combined Degeneration of the Spinal Cord Caused by Autoimmune Gastritis

K. Higuchi, T. Takeuchi, K. Ota, 2020, Internal medicine.

Interleukin-8 Stimulates Leukocyte Migration Across a Monolayer of Cultured Rabbit Gastric Epithelial Cells (Effect Associated with the Impairment of Gastric Epithelial Barrier Function)

A. Tarnawski, E. Sasaki, Y. Fujiwara, 1997, Digestive Diseases and Sciences.

Endoscopic bilateral revision after metal stent deployment for hepatic hilar obstruction using molting technique (with videos)

S. Ueno, K. Higuchi, T. Ogura, 2022, Therapeutic advances in gastroenterology.

Apoptosis, Dysbiosis and Expression of Inflammatory Cytokines are Sequential Events in the Development of 5‐Fluorouracil‐Induced Intestinal Mucositis in Mice

K. Higuchi, N. Hamouda, Kenjiro Matsumoto, 2017, Basic & clinical pharmacology & toxicology.

Mast cell chymase expression in Helicobacter pylori‐associated gastritis

T. Matsuo, M. Ohishi, K. Higuchi, 2003, Histopathology.

Dominant-negative mutant of c-Jun gene transfer: a novel therapeutic strategy for colorectal cancer

H. Mizuguchi, H. Iwao, E. Sasaki, 2004, Gene Therapy.

No Additive Effect Between Helicobacter pylori Infection and Portal Hypertensive Gastropathy on Inducible Nitric Oxide Synthase Expression in Gastric Mucosa of Cirrhotic Patients

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2004, Digestive Diseases and Sciences.

Lansoprazole, a Proton Pump Inhibitor, Suppresses Production of Tumor Necrosis Factor-α and Interleukin-1β Induced by Lipopolysaccharide and Helicobacter Pylori Bacterial Components in Human Monocytic Cells via Inhibition of Activation of Nuclear Factor-κB and Extracellular Signal-Regulated Kinase

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2009, Journal of clinical biochemistry and nutrition.

Clinical significance of gastroesophageal reflux disease with minimal change: a multicenter prospective observational study

K. Haruma, K. Higuchi, K. Nakada, 2022, Scientific Reports.

The Management of Recurrence of Hepatocellular Carcinoma Occurring Within 6 Months After Hepatic Resection: A Comparative Study Using a Propensity Score Matching Analysis

K. Higuchi, K. Uchiyama, A. Asai, 2021, Journal of Gastrointestinal Cancer.

Complete regression of recurrent esophageal carcinoma with reduced expression of glutathione S-transferase-π by treatment with continuous infusion of 5-fluorouracil and low-dose cisplatin infusion

H. Osugi, K. Tominaga, Toshio Watanabe, 1999, American Journal of Gastroenterology.

M2b macrophage elimination and improved resistance of mice with chronic alcohol consumption to opportunistic infections.

Sumihiro Suzuki, Makiko Kobayashi, K. Higuchi, 2015, The American journal of pathology.

Combined treatment with dipeptidyl peptidase 4 (DPP4) inhibitor sitagliptin and elemental diets reduced indomethacin-induced intestinal injury in rats via the increase of mucosal glucagon-like peptide-2 concentration

K. Higuchi, J. Kaunitz, S. Nouda, 2015, Journal of clinical biochemistry and nutrition.

Exogenous administration of mesenchymal stem cells ameliorates dextran sulfate sodium-induced colitis via anti-inflammatory action in damaged tissue in rats.

K. Ohta, K. Tominaga, Toshio Watanabe, 2008, Life sciences.

Sequential therapy involving an early switch from entecavir to pegylated interferon‐α in Japanese patients with chronic hepatitis B

A. Tamori, K. Higuchi, N. Kawada, 2018, Hepatology research : the official journal of the Japan Society of Hepatology.

A case of mucosa-associated lymphoid tissue lymphoma forming multiple lymphomatous polyposis in the small intestine.

K. Ohta, K. Tominaga, Toshio Watanabe, 2007, World journal of gastroenterology.

Rebamipide Prevents Delay of Acetic Acid-Induced Gastric Ulcer Healing Caused by Helicobacter pylori Infection in Mongolian Gerbils

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2002, Digestive Diseases and Sciences.

Development and validation of a simple and multifaceted instrument, GERD-TEST, for the clinical evaluation of gastroesophageal reflux and dyspeptic symptoms

K. Haruma, T. Joh, A. Oshio, 2017, World journal of gastroenterology.

Characteristics of refractory gastroesophageal reflux disease (GERD) symptoms -is switching proton pump inhibitors based on the patient's CYP2C19 genotype an effective management strategy?

K. Higuchi, T. Takeuchi, S. Harada, 2015, Internal medicine.

Dual antiplatelet therapy does not affect the incidence of low-dose aspirin-induced small intestinal mucosal injury in patients after percutaneous coronary intervention for coronary stenosis: a multicenter cross-sectional study

K. Tominaga, K. Higuchi, A. Asai, 2018, Journal of clinical biochemistry and nutrition.

Immunohistochemical Localization of Cells That Synthesize Leukotriene B4 in Human Gastric Mucosa

T. Shimizu, K. Higuchi, T. Arakawa, 1992, Journal of clinical gastroenterology.

Increased proliferation of middle to distal colonic cells during colorectal carcinogenesis in experimental murine ulcerative colitis.

K. Higuchi, I. Hirata, E. Morita, 2007, Oncology reports.

Neutrophil Accumulation in Development of Gastric Ulcer Induced by Submucosal Injection of Endothelin-1 in Rats

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2000, Digestive Diseases and Sciences.

Functional oesophageal epithelial defense against acid

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2006, InflammoPharmacology.

A randomized, placebo-controlled, double-blind clinical trial of rikkunshito for patients with non-erosive reflux disease refractory to proton-pump inhibitor: the G-PRIDE study

K. Haruma, H. Kusunoki, K. Murakami, 2014, Journal of Gastroenterology.

Strategies for peptic ulcer healing after 1 week proton pump inhibitor-based triple Helicobacter pylori eradication therapy in Japanese patients: differences of gastric ulcers and duodenal ulcers

K. Higuchi, E. Umegaki, T. Takeuchi, 2012, Journal of clinical biochemistry and nutrition.

Sofalcone, a gastroprotective drug, promotes gastric ulcer healing following eradication therapy for Helicobacter pylori: A randomized controlled comparative trial with cimetidine, an H2‐receptor antagonist

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2010, Journal of gastroenterology and hepatology.

Clinical utility of endoscopic ultrasound‐guided biliary drainage as a rescue of re‐intervention procedure for high‐grade hilar stricture

K. Higuchi, M. Kitano, T. Takeuchi, 2017, Journal of gastroenterology and hepatology.

Risk factors for postoperative bleeding and early death in percutaneous endoscopic gastrostomy: A multicenter retrospective study

K. Higuchi, Toshikazu Onishi, S. Nouda, 2021, Journal of gastroenterology and hepatology.

Colonoscopic differences of erosive and/or small ulcerative lesions for diagnosis of colonic inflammatory diseases

K. Higuchi, I. Hirata, E. Morita, 2010, Journal of gastroenterology and hepatology.

Clinical effects of adalimumab treatment with concomitant azathioprine in Japanese Crohn's disease patients.

K. Higuchi, S. Nouda, T. Kuramoto, 2013, World journal of gastroenterology.

Therapeutic Effects of Immunosuppressive Therapy After Anti-Viral Treatment in Patient Refractory Ulcerative Colitis with Cytomegalovirus Infection

K. Higuchi, E. Morita, Takuya Inoue, 2009 .

Therapeutic Drug Monitoring of Golimumab for the Prediction of Long-Term Clinical Remission in Patients with Ulcerative Colitis

K. Higuchi, Y. Tatsumi, Takuya Inoue, 2022, Digestion.

Comprehensive analysis of intestinal cytokine messenger RNA profile by real-time quantitative polymerase chain reaction in patients with inflammatory bowel disease.

N. Oshitani, K. Higuchi, T. Arakawa, 2003, International journal of molecular medicine.

Serum IL-13 Predicts Response to Golimumab in Bio-Naïve Ulcerative Colitis

K. Higuchi, T. Takeuchi, Shiro Nakamura, 2022, Journal of clinical medicine.

Oral Tacrolimus in Patients with Ulcerative Colitis

K. Higuchi, Takuya Inoue, K. Kakimoto, 2016 .

Production of Reactive Oxygen Species in Peripheral Blood is Increased in Individuals with Helicobacter pylori Infection and Decreased after its Eradication

E. Sasaki, K. Tominaga, Toshio Watanabe, 2006, Helicobacter.

Active and passive smoking and risk of ulcerative colitis: A case–control study in Japan

K. Sayama, Y. Hiasa, K. Higuchi, 2021, Journal of gastroenterology and hepatology.

Factors affecting response to proton pump inhibitor therapy in patients with gastroesophageal reflux disease: a multicenter prospective observational study

K. Haruma, K. Murakami, T. Joh, 2015, Journal of Gastroenterology.

Mechanisms of peptic ulcer recurrence: role of inflammation

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2002, InflammoPharmacology.

p59fyn is associated with the development of hepatic steatosis due to chronic ethanol consumption

K. Higuchi, S. Fukunishi, K. Miyaji, 2011, Journal of clinical biochemistry and nutrition.

The effects of a TGR5 agonist and a dipeptidyl peptidase IV inhibitor on dextran sulfate sodium‐induced colitis in mice

K. Higuchi, J. Kaunitz, S. Nouda, 2015, Journal of gastroenterology and hepatology.

Are gastroprotective drugs useful for gastric ulcer healing: Re-evaluation using current ICH E9 guidelines

K. Tominaga, Y. Fujiwara, N. Oshitani, 2007, Inflammopharmacology.

Prevention of NSAID-Induced Small Intestinal Mucosal Injury: Prophylactic Potential of Lansoprazole

K. Higuchi, K. Takeuchi, M. Murano, 2009, Journal of clinical biochemistry and nutrition.

Efficacy and endoscopic prediction of cytapheresis therapy in patients with refractory and steroid‐dependent ulcerative colitis

N. Oshitani, K. Higuchi, T. Arakawa, 2006 .

Efficacy and endoscopic prediction of cytapheresis therapy in patients with refractory and steroid-dependent ulcerative colitis

N. Oshitani, K. Higuchi, T. Arakawa, 2006 .

Nitric oxide stimulates prostaglandin synthesis in cultured rabbit gastric cells.

Y. Fujiwara, K. Higuchi, T. Arakawa, 1997, Prostaglandins.

Interleukin-10 gene transfer to peritoneal mesothelial cells suppresses peritoneal dissemination of gastric cancer cells due to a persistently high concentration in the peritoneal cavity

H. Iwao, M. Shiota, K. Tominaga, 2008, Cancer Gene Therapy.

In situ expression of cell adhesion molecules in chronic gastritis with Helicobacter pylori infection.

K. Higuchi, T. Arakawa, T. Kuroki, 1997, Journal of clinical gastroenterology.

Effect of a proton-pump inhibitor on intestinal microbiota in patients taking low-dose aspirin

K. Higuchi, T. Takeuchi, K. Ota, 2021, European Journal of Clinical Pharmacology.

Hepatectomy and liver regeneration in the results of treatment of colorectal liver metastasis

K. Higuchi, K. Uchiyama, A. Asai, 2020, Contemporary oncology.

Synergistic antitumor effect of combined 5-fluorouracil (5-FU) with 5-chloro-2,4-dihydroxypyridine on 5-FU-resistant gastric cancer cells: possible role of a dihydropyrimidine dehydrogenase-independent mechanism

E. Sasaki, K. Tominaga, Toshio Watanabe, 2007, Journal of Gastroenterology.

In vivo action of novel alkyl methyl quinolone alkaloids against Helicobacter pylori.

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2002, The Journal of antimicrobial chemotherapy.

Therapeutic Success with the Suppression of Helicobacter pylori of Intractable Gastric Ulcers

K. Higuchi, T. Arakawa, T. Fukuda, 1994 .

Gastrointestinal endoscopy in the era of the acute pandemic of coronavirus disease 2019: Recommendations by Japan Gastroenterological Endoscopy Society (Issued on April 9th, 2020)

H. Ogata, H. Tajiri, H. Inoue, 2020, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Induction of brain-derived neurotrophic factor in enteric glial cells stimulated by interleukin-1β via a c-Jun N-terminal kinase pathway.

K. Higuchi, T. Takeuchi, K. Ota, 2020, Journal of clinical biochemistry and nutrition.

New aspects of gastric adaptive relaxation, reflex after food intake for more food: involvement of capsaicin-sensitive sensory nerves and nitric oxide.

K. Higuchi, T. Arakawa, T. Kuroki, 1997, Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi.

Digest Itself? Prostaglandins, NSAIDs, and Gastric Mucosal Protection: Why Doesn't the Stomach

J. Wallace, E. Sasaki, K. Tominaga, 2009 .

EUS-guided versus percutaneous biliary access in patients with obstructive jaundice due to gastric cancer.

K. Higuchi, T. Ogura, D. Masuda, 2019, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Recent effectiveness of proton pump inhibitors for severe reflux esophagitis: the first multicenter prospective study in Japan

K. Haruma, T. Joh, K. Higuchi, 2015, Journal of clinical biochemistry and nutrition.

Mechanisms and Roles of Neutrophil Infiltration in Stress-Induced Gastric Injury in Rats

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2001, Digestive Diseases and Sciences.

Lafutidine, a histamine H2 receptor antagonist with mucosal protective properties, attenuates 5-fluorouracil-induced intestinal mucositis in mice through activation of extrinsic primary afferent neurons.

M. Tominaga, K. Higuchi, T. Takeuchi, 2017, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

Ligand for peroxisome proliferator-activated receptor-Γ inhibits proliferation and induces apoptosis of barrett's adenocarcinoma both in vitro and in vivo

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2003 .

EUS-guided cholecystoduodenostomy for acute cholecystitis with an anti-stent migration and anti-food impaction system; a pilot study

K. Higuchi, T. Takeuchi, S. Fukunishi, 2016, Therapeutic advances in gastroenterology.

Increased mRNA levels of transforming growth factor-beta1 and monocyte chemoattractant protein-1 in ulcer relapse caused by interleukin-1beta in rats.

H. Iwao, K. Tominaga, Y. Fujiwara, 1998, Digestive diseases and sciences.

Histologic diagnosis of pancreatic masses using 25-gauge endoscopic ultrasound needles with and without a core trap: a multicenter randomized trial

M. Kudo, M. Asada, K. Okazaki, 2016, Endoscopy.

Prospective histological evaluation of a 20G core trap with a forward-cutting bevel needle for EUS-FNA of pancreatic lesions

K. Higuchi, Y. Kurisu, T. Ogura, 2018, Surgical Endoscopy.

Novel adsorptive type apheresis device Immunopure for ulcerative colitis from clinical perspectives based on clinical trials: Japan and Europe

K. Higuchi, S. Kato, K. Kawasaki, 2021, Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.

Blue Mode Imaging may Improve the Detection and Visualization of Small-Bowel Lesions: A Capsule Endoscopy Study

K. Higuchi, E. Morita, S. Nouda, 2015, Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association.

Roles of ZO-1 and Epidermal Growth Factor in Esophageal Epithelial Defense against Acid

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2007, Digestion.

Perfectionism underlying psychological background correlated with the symptoms of functional dyspepsia

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2008, Journal of Gastroenterology.

Phenotypical and morphological analyses of intraepithelial and lamina propria lymphocytes in normal and regenerating gastric mucosa of rats in comparison with those in intestinal mucosa.

K. Higuchi, T. Arakawa, K. Kaneda, 2000, Archives of histology and cytology.

Present status and strategy of NSAIDs-induced small bowel injury

Toshio Watanabe, K. Higuchi, T. Arakawa, 2009, Journal of Gastroenterology.

Pentoxifylline Accelerates Gastric Ulcer Healing in Rats: Roles of Tumor Necrosis Factor Alpha and Neutrophils during the Early Phase of Ulcer Healing

Toshio Watanabe, Y. Fujiwara, K. Higuchi, 2000, Digestion.

TGF-beta signaling pathway: its role in gastrointestinal pathophysiology and modulation of ulcer healing.

A. Tarnawski, K. Higuchi, T. Arakawa, 2005, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

Crohn’s disease complicated by adult-onset Still’s disease

N. Oshitani, K. Higuchi, T. Arakawa, 2003, Journal of Gastroenterology.

[Peptic ulcer recurrence after successful eradication of Helicobacter pylori--clinical characteristics and management].

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2004, Nihon rinsho. Japanese journal of clinical medicine.

Comparison of the Effects of Vonoprazan and Lansoprazole for Treating Endoscopic Submucosal Dissection-Induced Artificial Ulcers

K. Tominaga, K. Higuchi, T. Takeuchi, 2018, Digestive Diseases and Sciences.

A case of retroperitoneal cystic lymphangioma in which cystic fluid analysis using EUS-FNA was useful for diagnosis

K. Higuchi, K. Uchiyama, Y. Kurisu, 2013 .

Primary hepatic MALT lymphoma associated with primary biliary cirrhosis.

T. Takubo, T. Hanafusa, K. Higuchi, 2010, Leukemia research.

Indomethacin treatment during initial period of acetic acid-induced rat gastric ulcer healing promotes persistent polymorphonuclear cell-infiltration and increases future ulcer recurrence

A. Tarnawski, Toshio Watanabe, K. Higuchi, 1996, Digestive Diseases and Sciences.

RoleofNeutrophils inaRatModelofGastric Ulcer Recurrence CausedbyInterleukin-1f3

Toshio Watanabe, K. Higuchi, T. Arakawa, 1997 .

Comparison of gastrointestinal symptoms and psychological factors of functional dyspepsia to peptic ulcer or panic disorder patients

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2007, Inflammopharmacology.

A case of senile woman diagnosed with autoimmune hepatitis, accompanied by hepatitis A virus infection

K. Higuchi, A. Asai, S. Fukunishi, 2012 .

Can Endoscopic Ultrasound-Guided Fine Needle Aspiration Offer Clinical Benefit for Thick-Walled Gallbladders?

K. Higuchi, Malak Mohamed, K. Uchiyama, 2014, Digestive Diseases and Sciences.

Examination on Factors Affecting Symptom Change after Drug Withdrawal in Patients with Mild Erosive Gastroesophageal Reflux Disease Undergoing Symptom-Controlled Maintenance Therapy with Acid-Secretion Inhibition Drugs

K. Higuchi, Taro Iwatsubo, T. Takeuchi, 2022, Digestion.

Randomised trial of acid inhibition by vonoprazan 10/20 mg once daily vs rabeprazole 10/20 mg twice daily in healthy Japanese volunteers (SAMURAI pH study)

Y. Fujiwara, K. Higuchi, Akinari Sawada, 2020, Alimentary pharmacology & therapeutics.

Rebamipide, a gastro-protective and anti-inflammatory drug, promotes gastric ulcer healing following eradication therapy for Helicobacter pylori in a Japanese population: a randomized, double-blind, placebo-controlled trial

A. Terano, K. Haruma, K. Murakami, 2007, Journal of Gastroenterology.

Efficacy of Prophylactic G-CSF in Patients Receiving FOLFIRINOX: A Preliminary Retrospective Study.

K. Higuchi, T. Kii, M. Goto, 2015, Internal medicine.

Asymptomatic Duodenal Metastasis From Small Cell Lung Cancer Diagnosed by Endoscopic Ultrasound-Guided Fine-Needle Aspiration

K. Higuchi, Y. Kurisu, T. Ogura, 2016 .

A review of treatment options for bile duct stones

K. Higuchi, T. Ogura, 2016, Expert review of gastroenterology & hepatology.

15th Anniversary of Rebamipide: Looking Ahead to the New Mechanisms and New Applications

T. Yoshikawa, A. Tarnawski, E. Sasaki, 2005, Digestive diseases and sciences.

Dislocation of tight junction proteins without F-actin disruption in inactive Crohn's disease.

Y. Fujiwara, N. Oshitani, K. Higuchi, 2005, International journal of molecular medicine.

Can Iodixanol Prevent Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis? A Prospective, Randomized, Controlled Trial

K. Higuchi, S. Fukunishi, T. Ogura, 2019, Digestive Diseases.

Effect of an Electronic Alert System on Hepatitis B Virus Reactivation in Patients Receiving Immunosuppressive Drug Therapy

K. Higuchi, A. Asai, T. Nishikawa, 2022, Journal of clinical medicine.

Fluoropyrimidine-induced intestinal mucosal injury is associated with the severity of chemotherapy-related diarrhea

K. Higuchi, T. Takeuchi, K. Ota, 2019, Scandinavian journal of gastroenterology.

Is eradication sufficient to heal gastric ulcers in patients infected with Helicobacter pylori? A randomized, controlled, prospective study

K. Tominaga, Y. Fujiwara, N. Oshitani, 2003, Alimentary pharmacology & therapeutics.

Long-term effect of Helicobacter pylori eradication on quality of life, body mass index, and newly developed diseases in Japanese patients with peptic ulcer disease.

Kazuhide Higuchi, Tetsuo Arakawa, Yasuhiro Fujiwara, 2002, Hepato-gastroenterology.

Influence of Rebamipide on Indometacin-induced Gastric Hemorrhage in Rats under Restraint Stress

K. Higuchi, T. Arakawa, T. Kuroki, 1999, Arzneimittelforschung.

Rebamipide prevents recurrence of gastric ulcers without affecting Helicobacter pylori status.

Y. Fujiwara, K. Higuchi, T. Arakawa, 1998, Digestive diseases and sciences.

Protective effect of rebamipide against ammonia-induced gastric mucosal lesions.

K. Tominaga, Y. Fujiwara, K. Higuchi, 1998, Digestive diseases and sciences.

Quality of ulcer healing influences the relapse of gastric ulcers in humans

K. Higuchi, T. Arakawa, H. Nebiki, 1997, Journal of gastroenterology and hepatology.

Transluminal stone removal from right intrahepatic bile duct using novel basket catheter

S. Ueno, K. Higuchi, T. Ogura, 2019, Endoscopy.

Prospective evaluation of digital single‐operator cholangioscope for diagnostic and therapeutic procedures (with videos)

M. Takenaka, K. Higuchi, M. Kitano, 2017, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Antiplatelet and/or anticoagulant treatment does not increase hemorrhagic adverse events during EUS-guided biliary drainage.

S. Ueno, K. Higuchi, T. Ogura, 2020, Gastrointestinal endoscopy.

Electrohydraulic Lithotripsy for Difficult Bile Duct Stones under Endoscopic Retrograde Cholangiopancreatography and Peroral Transluminal Cholangioscopy Guidance

K. Higuchi, T. Ogura, Akira Miyano, 2018, Gut and liver.

EUS-Guided Antegrade Biliary Stenting Using a Novel Fully Covered Metal Stent (with Video)

K. Higuchi, T. Ogura, Akira Miyano, 2018, Journal of Gastrointestinal Surgery.

Transluminal intrahepatic bile duct stone removal using a novel spiral basket catheter via the endoscopic ultrasound‐guided hepaticogastrostomy route (with video)

K. Higuchi, T. Ogura, Yoshitaro Yamamoto, 2022 .

Transluminal intrahepatic bile duct stone removal using a novel spiral basket catheter via the EUS-guided hepaticogastrostomy route (with video).

K. Higuchi, T. Ogura, Yoshitaro Yamamoto, 2021, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Transluminal common bile duct stone removal under digital cholangioscopic guidance

K. Higuchi, S. Fukunishi, T. Ogura, 2019, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Visualization and removal of intrahepatic bile duct stones through EUS-guided hepaticogastrostomy.

K. Higuchi, T. Takeuchi, S. Fukunishi, 2016, Gastrointestinal endoscopy.

Endoscopic sphincterotomy to prevent post-ERCP pancreatitis in patients with biliary neoplasms: a multicenter retrospective cohort study

M. Takenaka, K. Higuchi, H. Yamaue, 2020, Endoscopy International Open.

A feasibility study of digital single-operator cholangioscopy for diagnostic and therapeutic procedure (with videos)

K. Higuchi, Y. Kurisu, T. Ogura, 2017, Medicine.

Increased expression of transforming growth factor‐alpha and epidermal growth factor receptors in rat chronic reflux esophagitis

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2004, Journal of gastroenterology and hepatology.

Liu-Jun-Zi-Tang, a kampo medicine, promotes adaptive relaxation in isolated guinea pig stomachs.

K. Higuchi, T. Arakawa, A. Ishige, 1999, Drugs under experimental and clinical research.

[Pathogenesis and treatment of refractory gastroesophageal reflux disease in Japanese patients].

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2004, Nihon rinsho. Japanese journal of clinical medicine.

Autophagy deficiency exacerbates colitis through excessive oxidative stress and MAPK signaling pathway activation

K. Higuchi, S. Hosomi, T. Nakagawa, 2019, PloS one.

Probiotic Lactobacillus casei strain Shirota prevents indomethacin-induced small intestinal injury: involvement of lactic acid.

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2009, American journal of physiology. Gastrointestinal and liver physiology.

The Differential Diagnosis of Colorectal Polyps Using Colon Capsule Endoscopy

Yutaka Saito, K. Higuchi, S. Nouda, 2021, Internal medicine.

Prognostic value of K-ras mutation status and subtypes in endoscopic ultrasound-guided fine-needle aspiration specimens from patients with unresectable pancreatic cancer

Y. Yatabe, H. Imaoka, K. Higuchi, 2013, Journal of Gastroenterology.

Zinc deficiency delays gastric ulcer healing in rats

Toshio Watanabe, K. Higuchi, T. Arakawa, 1995, Digestive Diseases and Sciences.

Using Corticosteroids to Reshape the Gut Microbiome: Implications for Inflammatory Bowel Diseases

J. Gilbert, K. Higuchi, Yunwei Wang, 2015, Inflammatory bowel diseases.

Clinical Practice Guideline for Enteroscopy

T. Matsui, H. Ogata, K. Ohtsuka, 2017, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Guideline Clinical Practice Guideline for Enteroscopy

T. Matsui, H. Ogata, K. Ohtsuka, 2017 .

Adult intussusception caused by Yersinia enterocolitica enterocolitis.

K. Higuchi, Takuya Inoue, M. Murano, 2012, Internal medicine.

Multiple metastatic leiomyosarcoma of the pancreas: a first case report and review of the literature.

K. Higuchi, K. Uchiyama, Y. Kurisu, 2013, Internal medicine.

Microbiota-derived lactate accelerates colon epithelial cell turnover in starvation-refed mice

M. Yamazaki, K. Higuchi, K. Hase, 2013, Nature Communications.

Programmed Death 1 Ligand Expression in the Monocytes of Patients with Hepatocellular Carcinoma Depends on Tumor Progression

K. Higuchi, A. Asai, S. Fukunishi, 2020, Cancers.

Primary CD56+ NK/T-cell lymphoma of the rectum accompanied with refractory ulcerative colitis

K. Higuchi, I. Hirata, E. Morita, 2008, Journal of Gastroenterology.

Differential expression of vasoactive intestinal peptide receptor 1 expression in inflammatory bowel disease.

N. Oshitani, K. Higuchi, T. Arakawa, 2007, International journal of molecular medicine.

Tannin-phytobezoars with Gastric Outlet Obstruction Treated by Dissolution with Administration and Endoscopic Injection of Coca-ColaⓇ, Endoscopic Crushing, and Removal (with Video)

K. Higuchi, Taro Iwatsubo, T. Takeuchi, 2021, Internal medicine.

Efficacy and safety of hangeshashinto for treatment of GERD refractory to proton pump inhibitors

K. Higuchi, Takuya Inoue, M. Murano, 2019, Journal of Gastroenterology.

Differentiating intrahepatic splenosis from hepatocellular carcinoma

K. Higuchi, A. Asai, S. Fukunishi, 2022, Kanzo.

Recurrent Hepatic Inflammatory Pseudotumor in Asynchronism After Surgery of Inflammatory Pseudotumor Associated With Granulomatous Cholangitis

K. Higuchi, K. Uchiyama, Y. Kurisu, 2019, Journal of Medical Cases.

Clinical Outcome of Endoscopic Ultrasound-Guided Liver Abscess Drainage Using Self-Expandable Covered Metallic Stent (with Video)

K. Higuchi, M. Kitano, T. Takeuchi, 2015, Digestive Diseases and Sciences.

Giant liver cyst caused by tuberculosis infection and masquerading as malignant peritonitis

K. Higuchi, K. Uchiyama, Y. Kurisu, 2014, Endoscopy.

A Case of Eosinophilic Granuloma Presenting as a Small Submucosal Tumor

K. Higuchi, T. Takeuchi, Y. Kojima, 2017, Internal medicine.

Guidelines for Gastroenterological Endoscopy in Patients Undergoing Antithrombotic Treatment: 2017 Appendix on Anticoagulants Including Direct Oral Anticoagulants

N. Uedo, K. Murakami, Mototsugu Kato, 2018, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

The postoperative bleeding rate and its risk factors in patients on antithrombotic therapy who undergo gastric endoscopic submucosal dissection

K. Higuchi, E. Umegaki, T. Takeuchi, 2013, BMC Gastroenterology.

Successful hemostasis for refractory colonic diverticulum bleeding by clipping with polyglycolic acid sheets

K. Higuchi, Taro Iwatsubo, T. Takeuchi, 2021, VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy.

Effectiveness of second-look endoscopy after gastric endoscopic submucosal dissection in patients taking antithrombotic agents: a multicenter propensity score matching analysis

Y. Naito, N. Yoshida, H. Isomoto, 2022, Gastric Cancer.

Risk factors for perioperative bleeding in percutaneous endoscopic gastrostomy construction: A case series and retrospective preliminary investigation

K. Higuchi, T. Takeuchi, K. Ota, 2020, Geriatrics & gerontology international.

Is a proton-pump inhibitor necessary after endoscopic submucosal dissection for superficial esophageal neoplasms? A propensity score analysis

K. Higuchi, M. Shiba, Taro Iwatsubo, 2020, Therapeutic advances in gastroenterology.

Efficacy and safety of Helicobacter pylori eradication therapy immediately after endoscopic submucosal dissection

N. Uedo, I. Oda, Y. Naito, 2018, Journal of gastroenterology and hepatology.

Gastric ulcer healing after treatment of endoscopic submucosal dissection in Japanese: comparison of H2 receptor antagonist and proton pump inhibitor administration

K. Higuchi, E. Umegaki, T. Takeuchi, 2011, Journal of clinical biochemistry and nutrition.

Transluminal antegrade endoscopic lithotripsy for pancreatic duct stones (with video)

K. Higuchi, T. Ogura, N. Nishioka, 2018, Digestive Endoscopy.

Mo1321 PROSPECTIVE COMPARISON STUDY OF FRANSEEN NEEDLE AND STANDARD NEEDLE USE FOR PANCREATIC LESIONS UNDER EUS-GUIDANCE

S. Ueno, K. Higuchi, T. Ogura, 2018, Gastrointestinal Endoscopy.

Very Delayed Perforation after Esophageal Endoscopic Submucosal Dissection and Intralesional Triamcinolone Injection

K. Higuchi, Sang-Woong Lee, Taro Iwatsubo, 2022, Case Reports in Gastroenterology.

Risk factors for bleeding after endoscopic mucosal resection.

K. Tominaga, Toshio Watanabe, K. Higuchi, 2005, World journal of gastroenterology.

Efficacy and safety of 1-week Helicobacter pylori eradication therapy and 7-week rebamipide treatment after endoscopic submucosal dissection of early gastric cancer in comparison with 8-week PPI standard treatment: a randomized, controlled, prospective, multicenter study

N. Uedo, Y. Naito, N. Yagi, 2015, Gastric Cancer.

Treating an Intractable Jejunocutaneous Fistula by Endoscopic Metallic Stent Placement: A Case Report of Successful Palliative Endoscopic Treatment in a Case Demonstrating Peritoneal Dissemination with Terminal Stage Gastric Cancer

K. Higuchi, Taro Iwatsubo, T. Takeuchi, 2022, Internal medicine.

Sa1485 Risk Factors and Management Strategy for Ulcer Hemorrhage Following Gastric Endoscopic Submucosal Dissection in Patients on Antithrombotic Therapy

K. Higuchi, E. Umegaki, T. Takeuchi, 2013 .

EUS-Guided Antegrade Balloon Dilation From Right Hepatic Duct Combined With Retrograde Rendezvous Stent Placement.

K. Higuchi, M. Kitano, S. Fukunishi, 2015, Gastroenterology.

Endoscopic ultrasound-guided biliary drainage for right hepatic bile duct obstruction: novel technical tips

K. Higuchi, M. Kitano, Takuya Inoue, 2014, Endoscopy.

EUS-guided hepaticogastrostomy for hepatic hilar obstruction

K. Higuchi, E. Umegaki, T. Ogura, 2014, Endoscopy.

Double puncture of the stomach and duodenum during EUS-guided gallbladder drainage (with video)

K. Higuchi, T. Ogura, Atsushi Okuda, 2021, Endoscopic ultrasound.

Exploratory Research on Latent Esophageal Motility Disorders in Dysphagia Patients

K. Higuchi, T. Takeuchi, K. Ota, 2017, Digestion.

Superficial non-ampullary duodenal cancer identified by small-bowel capsule endoscopy: a case report (with video)

K. Higuchi, S. Nouda, T. Takeuchi, 2018, Clinical Journal of Gastroenterology.

Does the Novel Potassium-Competitive Acid Blocker Vonoprazan Cause More Hypergastrinemia than Conventional Proton Pump Inhibitors? A Multicenter Prospective Cross-Sectional Study

K. Tominaga, K. Higuchi, T. Takeuchi, 2018, Digestion.

No increase in gastric acid secretion in healthy Japanese over the past two decades

K. Higuchi, N. Ishimura, Y. Kinoshita, 2015, Journal of Gastroenterology.

A Case Series of Radiation-induced Hemorrhagic Gastroduodenitis

K. Higuchi, Taro Iwatsubo, T. Takeuchi, 2021, Internal medicine.

Gel immersion EUS-guided drainage for walled-off necrosis with poor visibility using a lumen-apposing metal stent (with video).

K. Higuchi, T. Ogura, Atsushi Okuda, 2022, Endoscopic ultrasound.

Adenocarcinoma arising in a heterotopic pancreas (Heinrich type III): a case report

K. Higuchi, N. Tanigawa, Y. Inoue, 2010, Journal of medical case reports.

Temporary insertion of a covered self-expandable metal stent to treat esophageal perforation due to endoscopic submucosal dissection.

K. Higuchi, T. Takeuchi, K. Ota, 2015, Internal medicine.

Temporary insertion of a covered self‐expandable metal stent for spontaneous esophageal rupture

K. Higuchi, T. Takeuchi, K. Ota, 2014, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Electrohydraulic Lithotripsy for Pancreatic Duct Stones Under Digital Single-Operator Pancreatoscopy (with Video)

K. Higuchi, T. Ogura, Akira Miyano, 2018, Digestive Diseases and Sciences.

Placement of a 6 mm, fully covered metal stent for main pancreatic head duct stricture due to chronic pancreatitis: a pilot study (with video)

K. Higuchi, M. Kitano, T. Takeuchi, 2016, Therapeutic advances in gastroenterology.

Innovation in Pancreatic Stents

K. Higuchi, T. Ogura, 2021, Gastrointestinal and Pancreatico-Biliary Diseases: Advanced Diagnostic and Therapeutic Endoscopy.

Pilot Study of Dumbbell-Type Covered Self-Expandable Metal Stent Deployment for Benign Pancreatic Duct Stricture (with Videos)

K. Higuchi, T. Ogura, Akira Miyano, 2018, Journal of Gastrointestinal Surgery.

Endoscopic Ultrasound-Guided Pancreatic Transmural Stenting and Transmural Intervention

K. Higuchi, H. Ohama, T. Ogura, 2019, Clinical endoscopy.

Narrow band imaging under less-air condition improves the visibility of superficial esophageal squamous cell carcinoma

N. Uedo, K. Higashino, R. Ishihara, 2020, BMC Gastroenterology.

A patient with obstructive jaundice.

K. Higuchi, T. Ogura, D. Masuda, 2013, Gastroenterology.

Placement of a novel fully covered metallic stent for refractory pancreatic duct stricture

K. Higuchi, Y. Kurisu, S. Fukunishi, 2015, Endoscopy.

Safe technique to treat occlusion of metallic endoscopic ultrasound-guided hepaticogastrostomy stent using a novel basket catheter (with video)

K. Higuchi, T. Ogura, A. Imoto, 2014, Endoscopy.

Non-steroidal anti-inflammatory drug-induced small intestinal damage is Toll-like receptor 4 dependent

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2007, Gut.

Potential predictors of disease progression for main‐duct intraductal papillary mucinous neoplasms of the pancreas

K. Higuchi, K. Uchiyama, Y. Kurisu, 2013, Journal of gastroenterology and hepatology.

Endoscopic Ultrasound-Guided Pancreatic Duct Drainage: Techniques and Literature Review of Transmural Stenting

K. Higuchi, T. Ogura, A. Imoto, 2020, Clinical endoscopy.

Technical tips for endoscopic ultrasound-guided hepaticogastrostomy.

K. Higuchi, T. Ogura, 2016, World journal of gastroenterology.

Comparison of the clinical impact of endoscopic ultrasound-guided choledochoduodenostomy and hepaticogastrostomy for bile duct obstruction with duodenal obstruction

H. Imaoka, K. Higuchi, M. Kitano, 2015, Endoscopy.

INDICATIONS FOR ENDOSCOPIC ULTRASOUND-GUIDED PANCREATIC DUCT DRAINAGE

K. Higuchi, T. Ogura, A. Imoto, 2020 .

Comparison Study between Double Bare Covered and Fully Covered Metal Stent during Endoscopic Ultrasound-Guided Choledochoduodenostomy (with Video)

K. Higuchi, T. Ogura, N. Nishioka, 2020, Digestive Diseases.

EUS-Guided Biliary Drainage

K. Higuchi, T. Ogura, 2019, Advanced Endoscopy.

Endoscopic ultrasound‐guided gallbladder drainage: Current status and future prospects

K. Higuchi, T. Ogura, 2019, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Evaluation of the safety of endoscopic radiofrequency ablation for malignant biliary stricture using a digital peroral cholangioscope (with videos)

K. Higuchi, T. Ogura, D. Masuda, 2017, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

EUS-FNA can be an effective procedure for the transesophageal drainage of a patient with intra-peritoneal abscess

K. Higuchi, S. Fukunishi, Y. Sasaki, 2015, Clinical Journal of Gastroenterology.

Endoscopic ultrasound‐guided choledochoduodenostomy using a thin stent delivery system in patients with unresectable malignant distal biliary obstruction: A prospective multicenter study

M. Kudo, M. Takenaka, K. Higuchi, 2019, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Multicenter prospective evaluation study of endoscopic ultrasound‐guided hepaticogastrostomy combined with antegrade stenting (with video)

M. Takenaka, K. Higuchi, Keiichi Hatamaru, 2018, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Technical tips of endoscopic ultrasound-guided choledochoduodenostomy.

K. Higuchi, T. Ogura, 2015, World journal of gastroenterology.

Comparison of the efficacy and safety of endoscopic ultrasound‐guided choledochoduodenostomy and hepaticogastrostomy for malignant distal biliary obstruction: Multicenter, randomized, clinical trial

M. Kudo, M. Takenaka, K. Higuchi, 2019, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Prospective clinical study of endoscopic ultrasound‐guided biliary drainage using novel balloon catheter (with video)

K. Higuchi, T. Ogura, D. Masuda, 2016, Journal of gastroenterology and hepatology.

Experimental Study of Endoscopic Ultrasound Guided Ethanol Injection in the Pancreas; Novel Strategy for Pancreatic Lesion

K. Higuchi, T. Arakawa, N. Mizuno, 2004 .

Electrohydraulic lithotripsy for pancreatic duct stones under temporary 6-mm fully covered metal stent placement

K. Higuchi, T. Ogura, Akira Miyano, 2018, Endoscopy.

Technical feasibility and safety of transluminal antegrade dilation for hepaticojejunostomy stricture using a novel fine-gauge electrocautery dilator (with video)

S. Ueno, K. Higuchi, R. Ashida, 2020, Endoscopy International Open.

Recanalization using diathermic dilator for stent obstruction due to tumor ingrowth

K. Higuchi, T. Ogura, A. Imoto, 2014, Endoscopy.

Endoscopic Evaluation of Neoadjuvant Chemotherapeutic Efficacy in Gastric Cancer before Gastrectomy Might be as Useful as Histological Assessment after Gastrectomy

Y. Hirose, K. Higuchi, Sang-Woong Lee, 2019, Digestion.

Hyperprogressive disease during nivolumab or irinotecan treatment in patients with advanced gastric cancer

K. Higuchi, Ken Kato, K. Nagashima, 2019, ESMO Open.

Expression of Gene for EIIIA- and EIIIB- Fibronectin, Fetal Types of Fibronectin, During Gastric Ulcer Healing in Rats

Shokei Kim, H. Iwao, K. Tominaga, 2001, Digestive Diseases and Sciences.

Torsion of an accessory spleen: a rare case preoperatively diagnosed and cured by single-port surgery

K. Higuchi, K. Uchiyama, Y. Narumi, 2015, Surgical Case Reports.

RETRACTED ARTICLE: Novel Therapeutic Approach Using Drug-loaded Adipose-derived Stem Cells for Pancreatic Cancer

K. Higuchi, M. Aoki, M. Goto, 2019, Scientific Reports.

Endoscopic ultrasound-guided hepaticogastrostomy combined with novel uncovered metal stent

K. Higuchi, T. Ogura, Akira Miyano, 2018, Endoscopy.

A novel endoscopic submucosal dissection technique for proton pump inhibitor-refractory gastroesophageal reflux disease

K. Higuchi, Takuya Inoue, T. Takeuchi, 2014, Scandinavian journal of gastroenterology.

Protective effect of roxatidine against indomethacin‐induced small intestinal mucosal injury in rats

K. Higuchi, M. Murano, E. Umegaki, 2010, Journal of gastroenterology and hepatology.

Effects of Oral L-Carnitine on Liver Functions after Transarterial Chemoembolization in Intermediate-Stage HCC Patients

K. Higuchi, A. Asai, S. Fukunishi, 2015, Mediators of inflammation.

Association between Administration of Antithrombotics and Intraperitoneal Hemorrhage in Patients Undergoing Percutaneous Interventions for Liver Diseases

K. Higuchi, A. Asai, S. Fukunishi, 2021, Journal of Clinical Medicine.

Cross‐reactivity of yeast antigens in human colon and peripheral leukocytes

K. Higuchi, T. Arakawa, K. Maeda, 2003, The Journal of pathology.

Endoscopic Findings of Ischemic Enteritis.

K. Higuchi, Takuya Inoue, K. Kawakami, 2015, Internal medicine.

Clinical impact of K-ras mutation analysis in EUS-guided FNA specimens from pancreatic masses.

Y. Yatabe, K. Higuchi, K. Hara, 2012, Gastrointestinal endoscopy.

Distinct Elevation of Levels of Anti-Caenorhabditis elegans Antibody in Sera of Patients with Inflammatory Bowel Disease

Y. Fujiwara, N. Oshitani, K. Higuchi, 2003, Clinical Diagnostic Laboratory Immunology.

Anti-Saccharmomyces cerevisiae Antibody in Inflammatory Bowel Disease

N. Oshitani, K. Higuchi, T. Arakawa, 2001 .

AP-1 and colorectal cancer

H. Iwao, E. Sasaki, K. Tominaga, 2006, InflammoPharmacology.

Massive Bleeding from a Small Intestinal Submucosal Tumor-like Arterial Malformation: An Unclassifiable Vascular Lesion Revealed by a Detailed Pathological Evaluation

Y. Hirose, K. Higuchi, S. Nouda, 2019, Internal medicine.

Immunopathological Features of Granuloma Formation in the Intestinal Mucosa of Patients with Crohn’s Disease

N. Oshitani, K. Higuchi, T. Arakawa, 2001 .

Ultra-structural study of the indomethacin-induced apoptosis and autophagy in rat gastric parietal cells

Yuko Ito, K. Higuchi, E. Abu-Dief, 2020, Ultrastructural pathology.

A previously undescribed form of intraductal papillary neoplasm of the bile duct

K. Higuchi, Y. Kurisu, E. Umegaki, 2013, Endoscopy.

Primary effusion lymphoma of T-cell origin with t(7;8)(q32;q13) in an HIV-negative patient with HCV-related liver cirrhosis and hepatocellular carcinoma positive for HHV6 and HHV8

T. Takubo, T. Hanafusa, K. Higuchi, 2011, Annals of Hematology.

Lansoprazole binding to the neutrophils in dextran sulfate sodium-induced rat colitis

Toshio Watanabe, K. Higuchi, T. Arakawa, 2006, InflammoPharmacology.

Effect of rebamipide on Helicobacter pylori infection in patients with peptic ulcer.

K. Higuchi, T. Arakawa, T. Kuroki, 1998, Digestive diseases and sciences.

Use of capsule endoscopy in patients with Crohn's disease in Japan: A multicenter survey

T. Hibi, H. Goto, N. Ohmiya, 2014, Journal of gastroenterology and hepatology.

Multiple Mesenteric Panniculitis as a Complication of Sjögren's Syndrome Leading to Ileus.

K. Higuchi, S. Nouda, Takuya Inoue, 2016, Internal medicine.

Evaluation of Deep Small Bowel Involvement by Double-Balloon Enteroscopy in Crohn's Disease

Y. Fujiwara, N. Oshitani, K. Higuchi, 2006, The American Journal of Gastroenterology.

Analysis of intestinal HLA-DR bound peptides and dysregulated immune responses to enteric flora in the pathogenesis of inflammatory bowel disease.

N. Oshitani, K. Higuchi, T. Arakawa, 2003, International journal of molecular medicine.

The efficacy of oral tacrolimus in patients with moderate/severe ulcerative colitis not receiving concomitant corticosteroid therapy.

K. Higuchi, S. Nouda, Takuya Inoue, 2013, Internal medicine.

Effects of oral tacrolimus as a rapid induction therapy in ulcerative colitis.

K. Higuchi, T. Arakawa, H. Yamagami, 2015, World journal of gastroenterology.

Evaluation of Portal Hypertensive Enteropathy by Scoring with Capsule Endoscopy: Is Transient Elastography of Clinical Impact?

K. Higuchi, E. Morita, S. Nouda, 2010, Journal of clinical biochemistry and nutrition.

[A case of ruptured ileal varices associated with alcoholic liver cirrhosis].

K. Higuchi, T. Arakawa, Seiko Yamaguchi, 2007, Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology.

EUS-guided FNA for biliary disease as first-line modality to obtain histological evidence

K. Higuchi, Y. Kurisu, S. Fukunishi, 2016, Therapeutic advances in gastroenterology.

Sarcopenia and Frailty in Liver Cirrhosis

K. Higuchi, A. Asai, S. Nishiguchi, 2021, Life.

Intra-gastric pH following single oral administrations of rabeprazole and esomeprazole: double-blind cross-over comparison

Mototsugu Kato, Y. Fujiwara, K. Higuchi, 2014, Journal of clinical biochemistry and nutrition.

Management of gastric fundal varices without gastro-renal shunt in 15 patients.

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2008, World journal of gastroenterology.

EUS-FNAで診断し，FDG-PETによる経時的変化を観察しえた黄色肉芽腫性胆嚢炎の1例

K. Higuchi, K. Uchiyama, Y. Kurisu, 2013 .

Liver dysfunction is associated with poor prognosis in patients after immune checkpoint inhibitor therapy

K. Higuchi, K. Uchiyama, A. Asai, 2020, Scientific Reports.

Efficacy of Postoperative Chemotherapy After Resection that Leaves No Macroscopically Visible Disease of Gastric Cancer with Positive Peritoneal Lavage Cytology (CY1) or Localized Peritoneum Metastasis (P1a): A Multicenter Retrospective Study

H. Katai, K. Higuchi, R. Makuuchi, 2019, Annals of Surgical Oncology.

Efficacy and safety of balloon-occluded endoscopic injection sclerotherapy as a prophylactic treatment for high-risk gastric fundal varices: a prospective, randomized, comparative clinical trial.

Y. Fujiwara, K. Higuchi, T. Arakawa, 2002, Gastrointestinal endoscopy.

Combined balloon-occluded embolization for treatment of concurrent duodenal, gastric, and esophageal varices: a case report.

R. Yamada, K. Nakamura, K. Tominaga, 2001, Gastrointestinal endoscopy.

Involvement of capsaicin-sensitive sensory nerves in gastric adaptive relaxation in isolated guinea-pig stomachs.

K. Higuchi, T. Arakawa, T. Fukuda, 1997, Digestion.

Geranylgeranylacetone suppresses colitis‑related mouse colon carcinogenesis.

K. Higuchi, S. Nouda, Takuya Inoue, 2015, Oncology reports.

Role of Nitric Oxide and Capsaicin-Sensitive Sensory Nerves in Gastric Receptive Relaxation and Adaptive Relaxation in Isolated Stomachs of Guinea Pigs

K. Higuchi, H. Uno, 2001 .

Structure of lamina propria lymphoid follicles and associated epithelium in the gastric mucosa during Helicobacter pylori infection in ulcer-bearing Mongolian gerbils.

K. Higuchi, T. Arakawa, T. Kuroki, 2000, Journal of submicroscopic cytology and pathology.

First report of a mucosa-associated lymphoid tissue (MALT) lymphoma of the esophagus diagnosed by endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA)

Y. Yatabe, K. Higuchi, K. Hara, 2012, Endoscopy.

Increased both PD–L1 and PD–L2 expressions on monocytes of patients with hepatocellular carcinoma was associated with a poor prognosis

K. Higuchi, A. Asai, S. Fukunishi, 2020, Scientific Reports.

Effect of Sofalcone on Localization of 15‐Hydroxyprostaglandin Dehydrogenase, An Enzyme That Metabolizes Prostaglandin E2, in Rat Gastric Mucosa: An Immunohistochemical Study

K. Higuchi, T. Arakawa, H. Nagura, 1992, Journal of clinical gastroenterology.

Obesity and Liver Cancer in Japan: A Comprehensive Review

K. Higuchi, A. Asai, S. Nishiguchi, 2021, AntiCancer Research.

Evaluation of Small Bowel Injury in Patients with Rheumatoid Arthritis by Capsule Endoscopy: Effects of Anti-Rheumatoid Arthritis Drugs

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2009, Digestion.

Growth inhibition of colon cancer cells by transfection of dominant-negative apoptosis signal-regulating kinase-1.

T. Nakao, H. Iwao, H. Ichijo, 2007, Oncology reports.

Endoscopic and Histopathological Evaluation of Collagenous Colitis

K. Higuchi, T. Kuramoto, Takuya Inoue, 2012, Digestion.

A Duodenal Ulcer Caused by Pancreatic Ductal Hypertension with Chronic Pancreatitis.

K. Higuchi, T. Mikami, Malak Mohamed, 2015, Internal medicine.

Geranylgeranylacetone, a gastromucoprotective drug, protects against NSAID-induced esophageal, gastroduodenal and small intestinal mucosal injury in healthy subjects: A prospective randomized study involving a comparison with famotidine.

K. Higuchi, S. Nouda, T. Kuramoto, 2014, Internal medicine.

A Social Program for the Early Detection of Pancreatic Cancer: The Kishiwada Katsuragi Project

M. Kudo, K. Higuchi, Y. Takeyama, 2017, Oncology.

Long-term efficacy of Helicobacter pylori eradication in patients with idiopathic thrombocytopenic purpura: 7-year follow-up prospective study

T. Nakao, T. Yamane, T. Yamane, 2009, Annals of Hematology.

Supragastric belching in Japan: lower prevalence and relevance for management of gastroesophageal reflux disease compared to United Kingdom

A. Masamune, Y. Fujiwara, K. Higuchi, 2020, Journal of Gastroenterology.

[Rumination syndrome in an adult with normal intelligence].

E. Sasaki, K. Tominaga, Toshio Watanabe, 2006, Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology.

Rikkunshito simultaneously improves dyspepsia correlated with anxiety in patients with functional dyspepsia: A randomized clinical trial (the DREAM study)

H. Kusunoki, K. Murakami, T. Chiba, 2018, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

VIDEO CUPSULE ENDOSCOPY WAS USEFUL IN EVALUATING THE SEVERITY OF HENOCH-SCHONLEIN PURPURA. REPORT OF A CASE

K. Higuchi, E. Morita, S. Nouda, 2008 .

Cigarette smoking and alcohol consumption associated with gastro-oesophageal reflux disease in Japanese men.

K. Tominaga, Y. Fujiwara, N. Oshitani, 2003, Scandinavian journal of gastroenterology.

Is Helicobacter pylori-Negative Duodenal Ulcer Masked by the High Prevalence of H. pylori Infection in the General Population?

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 1999, American Journal of Gastroenterology.

THE ROLE OF LINEAR ARRAY EUS FOR DIAGNOSIS OF PANCREATIC MALIGNANCIES IN THE CURRENT SITUATION

K. Higuchi, R. Ashida, Yoshifumi Arisaka, 2011, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Significance of Chymase-Dependent Matrix Metalloproteinase-9 Activation on Indomethacin-Induced Small Intestinal Damages in Rats

S. Takai, K. Higuchi, Takuya Inoue, 2010, Journal of Pharmacology and Experimental Therapeutics.

Role of Chymase-Dependent Matrix Metalloproteinase-9 Activation in Mice with Dextran Sodium Sulfate-Induced Colitis

S. Takai, M. Miyazaki, K. Higuchi, 2008, Journal of Pharmacology and Experimental Therapeutics.

Close association between activated platelets and neutrophils in the active phase of ulcerative colitis in humans

Y. Fujiwara, N. Oshitani, K. Higuchi, 2006, Inflammatory bowel diseases.

Cytomegalovirus infection in ulcerative colitis assessed by quantitative polymerase chain reaction: risk factors and effects of immunosuppressants

K. Tominaga, K. Higuchi, T. Mikami, 2018, Journal of clinical biochemistry and nutrition.

Outpatient Treatment of Moderately Severe Active Ulcerative Colitis with Pulsed Steroid Therapy and Conventional Steroid Therapy

N. Oshitani, K. Higuchi, T. Arakawa, 2003, Digestive Diseases and Sciences.

Efficacy and Effective Endoscopic Findings of Granulocyte and Monocyte Absorption Apheresis (GCAP) and Leukocytapheresis (LCAP) Therapy in Patients with Refractory Active Ulcerative Colitis (UC)

N. Oshitani, K. Higuchi, T. Arakawa, 2004 .

Effect of adalimumab on an enterocutaneous fistula in patients with Crohn's disease: a case series.

K. Higuchi, S. Nouda, Takuya Inoue, 2015, Internal medicine.

Oral tacrolimus for megacolon in patients with severe ulcerative colitis.

K. Higuchi, S. Nouda, Takuya Inoue, 2014, Internal medicine.

[Mechanism and management of drug-induced eating disorder].

K. Higuchi, T. Arakawa, T. Tanigawa, 2001, Nihon rinsho. Japanese journal of clinical medicine.

Significance of increased proliferation of immature plasma cells in the appendix of patients with ulcerative colitis.

Y. Fujiwara, N. Oshitani, K. Higuchi, 2005, International journal of molecular medicine.

Evidence-based clinical practice guidelines for functional dyspepsia 2021

T. Joh, T. Shimosegawa, Mototsugu Kato, 2022, Journal of Gastroenterology.

Host antitumor resistance improved by the macrophage polarization in a chimera model of patients with HCC

Makiko Kobayashi, K. Higuchi, F. Suzuki, 2017, Oncoimmunology.

Sildenafil-induced esophageal ulcers

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2001, American Journal of Gastroenterology.

Endoscopic resection of a cavernous haemangioma of the stomach.

K. Wakasa, Y. Fujiwara, K. Higuchi, 2002, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

[Post infectious irritable bowel syndrome experimental model].

N. Oshitani, K. Higuchi, T. Arakawa, 2006, Nihon rinsho. Japanese journal of clinical medicine.

Diagnosis of borderline adenomas of the stomach by endoscopic mucosal resection.

K. Wakasa, Y. Fujiwara, K. Higuchi, 1996, Endoscopy.

Food/nutrient intake and risk of atrophic gastritis among the Helicobacter pylori‐infected population of northeastern Japan

M. Inoue, S. Tsugane, S. Sasazuki, 2003, Cancer science.

Genetic and Epigenetic Markers to Identify High Risk Patients for Multiple Early Gastric Cancers after Treatment with Endoscopic Mucosal Resection

M. Fukuda, K. Higuchi, T. Arakawa, 2007, Journal of clinical biochemistry and nutrition.

Comparative study of conventional colonoscopy and pan-colonic narrow-band imaging system in the detection of neoplastic colonic polyps: a randomized, controlled trial

Takuya Inoue, Kazuhide Higuchi, Ken Kawakami, 2008, Journal of Gastroenterology.

Augmented O-GlcNAcylation alleviates inflammation-mediated colon carcinogenesis via suppression of acute inflammation

K. Higuchi, T. Nakagawa, Kazumasa Moriwaki, 2018, Journal of clinical biochemistry and nutrition.

Impact of age at diagnosis of head and neck cancer on incidence of metachronous cancer

N. Uedo, K. Higashino, R. Ishihara, 2019, BMC Cancer.

Pneumatosis cystoides intestinalis in a patient with ulcerative colitis.

K. Higuchi, T. Mikami, T. Takeuchi, 2017, Journal of gastrointestinal and liver diseases : JGLD.

Endoscopic resection of two granular cell tumours of the oesophagus.

K. Tominaga, Y. Fujiwara, K. Higuchi, 1999, European journal of gastroenterology & hepatology.

Oesophageal cavernous haemangioma diagnosed histologically, not by endoscopic procedures

N. Suzuki, K. Tominaga, Toshio Watanabe, 2000, Journal of gastroenterology and hepatology.

[The mechanisms of gastrointestinal mucosal injury and repair].

K. Kashima, K. Higuchi, T. Arakawa, 1998, Nihon rinsho. Japanese journal of clinical medicine.

Screening Tools for Sarcopenia

K. Higuchi, A. Asai, S. Nishiguchi, 2021, In Vivo.

Prognostic Impact of Ectopic Fat Deposition within Psoas Muscle in Stage IV Gastric Cancer Patients Undergoing Systemic Chemotherapy

K. Higuchi, Shiro Nakamura, T. Terazawa, 2022, Journal of Cancer.

Analysis of autonomic function during natural defecation in patients with irritable bowel syndrome using real-time recording with a wearable device

Y. Fujiwara, K. Higuchi, M. Shiba, 2022, PloS one.

Famotidine vs. omeprazole: a prospective randomized multicentre trial to determine efficacy in non‐erosive gastro‐oesophageal reflux disease

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2005, Alimentary pharmacology & therapeutics.

Gastroprotection by Liu-Jun-Zi-Tang (TJ-43): possible mediation of nitric oxide but not prostaglandins or sulfhydryls.

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 1999, Drugs under experimental and clinical research.

Novel transluminal treatment protocol for hepaticojejunostomy stricture using covered self-expandable metal stent

S. Ueno, K. Higuchi, T. Ogura, 2020, Surgical Endoscopy.

Spontaneous tearing of a duodenal metallic stent: a rare adverse event

K. Higuchi, T. Takeuchi, S. Fukunishi, 2015, Endoscopy.

Hole-making technique for the treatment for acute pancreatitis due to placement of a fully covered duodenal metallic stent

K. Higuchi, S. Fukunishi, T. Ogura, 2015, Endoscopy.

EUS-Guided Gallbladder Drainage Using an Improved Self-Expandable Covered Metal Stent with Anti-Stent Migration System (with Video)

K. Higuchi, T. Ogura, N. Nishioka, 2020, Digestive Diseases.

EUS-guided gallbladder drainage and hepaticogastrostomy for acute cholecystitis and obstructive jaundice (with video)

K. Higuchi, E. Umegaki, T. Ogura, 2014, Endoscopy.

Endoscopic ultrasound-guided gallbladder drainage: Results of long-term follow-up

K. Higuchi, H. Okasha, T. Ogura, 2018, Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association.

Stent release within scope channel technique to prevent stent migration during EUS-guided hepaticogastrostomy (with video)

K. Higuchi, T. Ogura, Akira Miyano, 2018, Endoscopic ultrasound.

EUS-guided hepaticojejunostomy combined with antegrade stent placement.

K. Higuchi, K. Uchiyama, Takuya Inoue, 2015, Gastrointestinal endoscopy.

One‐step deployment for EUS‐guided gallbladder drainage using a novel fully covered metal stent (with video)

S. Ueno, K. Higuchi, T. Ogura, 2020, Journal of hepato-biliary-pancreatic sciences.

Choledochoduodenal Fistula after the Placement of a Partially Covered Metal Stent for Unresectable Pancreatic Cancer.

K. Higuchi, Takuya Inoue, T. Takeuchi, 2016, Internal medicine.

Novel method of endoscopic ultrasound‐guided hepaticogastrostomy to prevent stent dysfunction

K. Higuchi, K. Uchiyama, Y. Kurisu, 2014, Journal of gastroenterology and hepatology.

EUS-guided hepaticogastrostomy combined with fine-gauge antegrade stenting: a pilot study

K. Higuchi, Malak Mohamed, E. Umegaki, 2014, Endoscopy.

Double-guidewire technique using a novel ERCP cannula for hepatic hilar obstruction

K. Higuchi, E. Umegaki, T. Ogura, 2014, Endoscopy.

EUS-guided hepaticojejunostomy using a 22G needle and novel 0.018-inch guidewire (with video)

S. Ueno, K. Higuchi, T. Ogura, 2022, Endoscopic ultrasound.

Partially covered self-expandable metal stent with antimigratory single flange plays important role during EUS-guided hepaticogastrostomy

S. Ueno, K. Higuchi, T. Ogura, 2022, Endoscopy international open.

Technical feasibility and safety of one-step deployment of EUS-guided hepaticogastrostomy using an 8-mm diameter metal stent with a fine-gauge stent delivery system (with video)

S. Ueno, K. Higuchi, T. Ogura, 2021, Endoscopic ultrasound.

Expanding indications for endoscopic ultrasound‐guided hepaticogastrostomy for patients with insufficient dilatation of the intrahepatic bile duct using a 22G needle combined with a novel 0.018‐inch guidewire (with video)

S. Ueno, K. Higuchi, T. Ogura, 2021, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

EUS‐guided hepaticogastrostomy for hepaticojejunostomy stricture using a 22G needle and a mechanical dilator (with video)

S. Ueno, K. Higuchi, T. Ogura, 2021, Journal of hepato-biliary-pancreatic sciences.

Endoscopic ultrasound‐guided hepaticogastrostomy for hepaticojejunostomy stricture using a one‐step stent deployment technique (with video)

K. Higuchi, T. Ogura, Atsushi Okuda, 2020, Journal of hepato-biliary-pancreatic sciences.

Transluminal antegrade biopsy using a novel forceps biopsy device for hepaticojejunostomy stricture

K. Higuchi, T. Ogura, Atsushi Okuda, 2020, Endoscopy.

Effect of echoendoscope angle on success of guidewire manipulation during endoscopic ultrasound-guided hepaticogastrostomy

S. Ueno, K. Higuchi, T. Ogura, 2020, Endoscopy.

Long-term outcomes of EUS-guided transluminal stent deployment for benign biliary disease: Multicenter clinical experience (with videos)

M. Kudo, M. Takenaka, K. Higuchi, 2019, Endoscopic ultrasound.

Technical feasibility of EUS-guided antegrade dilation for hepaticojejunostomy anastomotic stricture using novel endoscopic device (with videos)

K. Higuchi, T. Ogura, Akira Miyano, 2019, United European gastroenterology journal.

Intrahepatic bile duct stone removal through endoscopic ultrasound-guided hepaticogastrostomy using novel basket catheter under digital cholangioscopy guidance

K. Higuchi, T. Ogura, Akira Miyano, 2018, Endoscopy.

Technical Review of Developments in Endoscopic Ultrasound-Guided Hepaticogastrostomy

K. Higuchi, T. Ogura, 2021, Clinical endoscopy.

A CASE OF RADIATION PROCTITIS SUCCESSFULLY TREATED BY ARGON PLASMA COAGULATION THERAPY

Yoshihisa Watanabe, N. Oshitani, K. Higuchi, 2003 .

O-GlcNAcylation-mediated degradation of FBXL2 stabilizes FOXM1 to induce cancer progression.

K. Higuchi, Kazumasa Moriwaki, T. Takeuchi, 2020, Biochemical and biophysical research communications.

In Vitro Adaptive Cytoprotection in Gastric Cells Isolated from Rat Stomach

K. Higuchi, T. Arakawa, T. Fukuda, 1990, Journal of Clinical Gastroenterology.

USEFULNESS OF HEATER PROBE ON HEMOSTASIS OF LOCALIZED TELANGIECTASIA IN UPPER GASTROINTESTINAL TRACT: A REPORT OF THREE CASES

K. Higuchi, T. Arakawa, H. Satoh, 1994 .

Esophagogastric varices due to arterioportal shunt in a serous cystadenoma of the pancreas in von Hippel-Lindau disease.

A. Tamori, K. Wakasa, T. Shuin, 2003, Digestive diseases and sciences.

Administration of a standard dose of vonoprazan fumarate delays gastric emptying in Japanese healthy adults: a prospective clinical trial

K. Higuchi, K. Nakada, Taro Iwatsubo, 2021, Journal of Gastroenterology.

Small bowel injury by low-dose enteric-coated aspirin and treatment with misoprostol: a pilot study.

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2008, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Case of massive hematemesis by secondary aortic duodenal fistula 8 years after abdominal aortic aneurysm repair

K. Higuchi, T. Takeuchi, K. Ota, 2017, Geriatrics & Gerontology International.

A prospective, single-blind trial comparing wireless capsule endoscopy and double-balloon enteroscopy in patients with obscure gastrointestinal bleeding

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2008, Journal of Gastroenterology.

Can Endoscopic Ultrasound-Guided Fine Needle Aspiration Offer Clinical Benefit for Tumors of the Ampulla of Vater? -An Initial Study

Y. Yatabe, H. Imaoka, K. Higuchi, 2012, Endoscopic ultrasound.

Thoracic aorto-esophageal fistula following endovascular aneurysm repair.

K. Higuchi, K. Ota, Yoshimasa Hirata, 2015, Internal medicine.

Retrospective Comparison of mFOLFOXIRI With XELOX/SOX as Neoadjuvant Chemotherapy for Locally Advanced Rectal Cancer

K. Higuchi, K. Uchiyama, T. Kii, 2021, In Vivo.

Is proton pump inhibitor therapy for reflux esophagitis sufficient?: a large real-world survey of Japanese patients.

K. Haruma, T. Joh, K. Higuchi, 2013, Internal medicine.

Oxidized low-density lipoprotein levels circulating in plasma and deposited in the tissues: comparison between Helicobacter pylori-associated gastritis and acute myocardial infarction.

K. Higuchi, T. Arakawa, H. Itabe, 2004, American heart journal.

A Case of Eosinophilic Gastroenteritis Remission Achieved Steroid-Free With Mepolizumab

K. Higuchi, Yuki Hirata, Takahiko Nakamura, 2022, Gastro Hep Advances.

A case of mucinous cystadenocarcinoma of the pancreas with spontaneous rupture diagnosed by endoscopic retrograde pancreatography

K. Higuchi, K. Uchiyama, Y. Kurisu, 2013, Endoscopy.

Does colitis associated with primary sclerosing cholangitis represent an actual subset of ulcerative colitis?

S. Seki, N. Oshitani, K. Higuchi, 2003, Hepato-Gastroenterology.

Co-Administration of Saireito Enabled the Withdrawal of Corticosteroids in an Elderly Woman with Autoimmune Hepatitis.

K. Higuchi, A. Asai, S. Fukunishi, 2016, Internal medicine.

Yield of endoscopic ultrasound-guided fine needle aspiration and endoscopic retrograde cholangiopancreatography for solid pancreatic neoplasms

K. Higuchi, E. Sabet, T. Ogura, 2016, Scandinavian journal of gastroenterology.

Endoscopic Ultrasound-Guided Hepaticogastrostomy: Technical Review and Tips to Prevent Adverse Events

K. Higuchi, T. Ogura, 2020, Gut and liver.

Stent length is impact factor associated with stent patency in endoscopic ultrasound‐guided hepaticogastrostomy

K. Higuchi, S. Fukunishi, Kazuhiro Yamamoto, 2015, Journal of gastroenterology and hepatology.

Updated Efficacy Outcomes of Anti-PD-1 Antibodies plus Multikinase Inhibitors for Patients with Advanced Gastric Cancer with or without Liver Metastases in Clinical Trials

K. Higuchi, T. Yoshino, T. Kuwata, 2022, Clinical cancer research : an official journal of the American Association for Cancer Research.

Concurrent assessment of reservoir and emptying of the stomach for dyspepsia patients.

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2008, Hepato-gastroenterology.

Rosuvastatin as a potential preventive drug for the development of hepatocellular carcinoma associated with non-alcoholic fatty liver disease in mice.

K. Higuchi, A. Asai, Masaaki Ii, 2016, International journal of molecular medicine.

Rebamipide Reduces Delay in Gastric Ulcer Healing in Cyclooxygenase-2-Deficient Mice

E. Sasaki, K. Tominaga, Toshio Watanabe, 2005, Digestive Diseases and Sciences.

Comparison of the effects of individual symptoms of gastroesophageal reflux disease co‐existing functional dyspepsia on patients' daily lives: A prospective, observational study

M. Saruta, K. Haruma, A. Oshio, 2022, JGH open : an open access journal of gastroenterology and hepatology.

The early therapeutic response at 2 weeks is a crucial predictor of proton pump inhibitor-refractory gastroesophageal reflux disease

M. Saruta, K. Haruma, T. Joh, 2020, Esophagus.

Proton pump inhibitor monotherapy is effective to attenuate dyspepsia symptoms associated with gastroesophageal reflux disease: a multicenter prospective observational study

K. Haruma, T. Joh, K. Higuchi, 2019, Journal of Gastroenterology.

Therapy of gastroesophageal reflux disease and functional dyspepsia overlaps with symptoms after usual‐dose proton pump inhibitor: Acotiamide plus usual‐dose proton pump inhibitor versus double‐dose proton pump inhibitor

K. Tominaga, K. Higuchi, M. Kusano, 2017, Journal of gastroenterology and hepatology.

Rikkunshito improves symptoms in PPI-refractory GERD patients: a prospective, randomized, multicenter trial in Japan

Mio Tanaka, K. Tominaga, Y. Fujiwara, 2012, Journal of Gastroenterology.

Short-term and long-term outcome of endoluminal gastroplication for the treatment of GERD: the first multicenter trial in Japan

H. Kuwano, M. Asaka, Mototsugu Kato, 2009, Journal of Gastroenterology.

Experimental study of loop shape using 0.025-inch ERCP guidewires (with videos)

S. Ueno, K. Higuchi, T. Ogura, 2021, Endoscopy International Open.

Gastrointestinal: Knuckle guidewire insertion: Safe techniques of guidewire insertion into the pancreatobiliary tract using a novel 0.025‐inch guidewire

K. Higuchi, T. Ogura, N. Nishioka, 2019, Journal of gastroenterology and hepatology.

Single‐session multiple stent deployment using moving cell stent without dilating initial stent mesh to treat malignant hilar biliary obstruction (with videos)

M. Takenaka, S. Ueno, K. Higuchi, 2019, Journal of hepato-biliary-pancreatic sciences.

Hybrid placement technique for hepatic hilar obstruction using a new uncovered self-expandable metal stent

S. Ueno, K. Higuchi, S. Fukunishi, 2019, Endoscopy International Open.

Clinical evaluation of physician-controlled guidewire manipulation during endoscopic ultrasound-guided hepaticogastrostomy (with video)

S. Ueno, K. Higuchi, T. Ogura, 2021, Endoscopy International Open.

Clinical Impact of the Intra-scope Channel Stent Release Technique in Preventing Stent Migration During EUS-Guided Hepaticogastrostomy

K. Higuchi, Kazuhiro Yamamoto, T. Ogura, 2018, Journal of Gastrointestinal Surgery.

Liver impaction technique to prevent shearing of the guidewire during endoscopic ultrasound-guided hepaticogastrostomy

K. Higuchi, T. Takeuchi, S. Fukunishi, 2015, Endoscopy.

Prospective multicenter evaluation of moving cell metallic stents in endoscopic multiple stent deployment for hepatic hilar obstruction

M. Takenaka, S. Ueno, K. Higuchi, 2021, Journal of hepato-biliary-pancreatic sciences.

Reverse knuckle guidewire insertion technique for endoscopic ultrasound-guided hepaticogastrostomy using a novel 0.025-inch guidewire

S. Ueno, K. Higuchi, T. Ogura, 2020, Endoscopy.

Endoscopic ultrasound-guided biliary drainage with a novel fine-gauge balloon catheter: simplified technique using a coaxial guidewire

K. Higuchi, T. Takeuchi, S. Fukunishi, 2015, Endoscopy.

Novel guidewire with coiled tip improves technical success of guidewire manipulation during EUS-guided biliary drainage (with video)

S. Ueno, K. Higuchi, T. Ogura, 2022, Endoscopic ultrasound.

Moving scope technique for guidewire insertion during endoscopic ultrasound‐guided hepaticogastrostomy

S. Ueno, K. Higuchi, T. Ogura, 2021, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Technical tips for peroral transluminal cholangioscopy using novel single‐operator cholangioscope (with videos)

K. Higuchi, Y. Kurisu, T. Ogura, 2016, Journal of hepato-biliary-pancreatic sciences.

Endoscopic ultrasonography‐guided hepaticogastrostomy using a novel laser‐cut type partially covered self‐expandable metal stent (with video)

S. Ueno, K. Higuchi, Yasunobu Yamashita, 2021, Digestive Endoscopy.

Fistula formation after EUS-guided hepaticogastrostomy.

K. Higuchi, T. Takeuchi, S. Fukunishi, 2016, Gastrointestinal Endoscopy.

Does endoscopic ultrasound-guided biliary drainage really have clinical impact?

K. Higuchi, T. Ogura, 2015, World Journal of Gastroenterology.

Reintervention after deployment of several metal stents using novel fine‐gauge electrocautery dilator

K. Higuchi, T. Ogura, M. Yamada, 2019, Digestive Endoscopy.

Success of stent-in-stent deployment after intraductal radiofrequency ablation for hepatic hilar obstruction

S. Ueno, K. Higuchi, T. Ogura, 2019, Endoscopy.

Novel fine gauge electrocautery dilator for endoscopic ultrasound-guided biliary drainage: experimental and clinical evaluation study (with video)

T. Itoi, K. Higuchi, T. Iwashita, 2019, Endoscopy International Open.

Intraluminal water filling technique to prevent double mucosal puncture during EUS-guided choledochoduodenostomy.

K. Higuchi, T. Takeuchi, S. Fukunishi, 2016, Gastrointestinal endoscopy.

Endoscopic ultrasound-guided biliary drainage for malignant biliary obstruction with surgically altered anatomy: a multicenter prospective registration study

M. Kudo, M. Takenaka, K. Higuchi, 2020, Therapeutic advances in gastroenterology.

Endoscopic nasal biliary drainage-guided approach after endoscopic ultrasound-guided hepaticojejunostomy: safe stent exchange technique

S. Ueno, K. Higuchi, T. Ogura, 2020, Endoscopy.

EUS-Guided Hepaticojejunostomy Using Novel Plastic Stent Combined with Antegrade Metal Stent Placement

K. Higuchi, T. Ogura, N. Nishioka, 2018, Journal of Gastrointestinal Surgery.

Prospective comparison study between 19G needle with 0.025-inch guidewire and 22G needle with novel 0.018-inch guidewire during EUS-guided transhepatic biliary drainage (with video).

S. Ueno, K. Higuchi, T. Ogura, 2022, Gastrointestinal endoscopy.

Jumping technique for guidewire manipulation within an intrahepatic bile duct during EUS-guided biliary drainage (with video)

S. Ueno, K. Higuchi, T. Ogura, 2021, Endoscopic ultrasound.

Intrahepatic bile duct stone removal using peroral transluminal cholangioscopy (with videos)

K. Higuchi, T. Ogura, Atsushi Okuda, 2018, Endoscopic ultrasound.

Recanalization for Tight Bile Duct-Jejunum Anastomosis Stricture Using Peroral Transliminal Cholangioscopy (with Video)

K. Higuchi, T. Ogura, Akira Miyano, 2018, Digestive Diseases.

Propensity score matching analysis for adverse events of EUS-guided biliary drainage in advanced elderly patients (PEACE study)

K. Higuchi, N. Fujimori, T. Oono, 2022, Therapeutic advances in gastroenterology.

Reintervention technique with insertion of an uncovered metal stent by a 5.4-Fr delivery system for an occluded endoscopic ultrasound-guided hepaticogastrostomy stent

K. Higuchi, T. Ogura, Atsushi Okuda, 2021, Endoscopy.

Double intrahepatic bile duct puncture: a pitfall during endoscopic ultrasound-guided hepaticogastrostomy

K. Higuchi, T. Ogura, Akira Miyano, 2018, Endoscopy.

Fine-gauge balloon-assisted stent removal technique for ruptured EUS-guided hepaticojejunostomy plastic stents (with video)

S. Ueno, K. Higuchi, T. Ogura, 2020, Endoscopic ultrasound.

Ulcerogenicity and effect on inhibition of prostaglandin generation of indometacin farnesil, a prodrug of indomethacin, in rat gastric mucosa: comparison with indomethacin or loxoprofen.

K. Tominaga, K. Higuchi, T. Arakawa, 1995, Drugs under experimental and clinical research.

CASE REPORT: Asymptomatic Chronic Intestinal Ischemia Caused by Idiopathic Phlebosclerosis of Mesenteric Vein

A. Tamori, S. Seki, N. Oshitani, 2002, Digestive Diseases and Sciences.

New reduced volume preparation regimen in colon capsule endoscopy.

H. Tajiri, H. Goto, N. Ohmiya, 2012, World journal of gastroenterology.

Color Analysis for Segmenting Digestive Organs in VCE

Yasushi Yagi, Hai Vu, Tomio Echigo, 2010, 2010 20th International Conference on Pattern Recognition.

Effect of egualen sodium hydrate on small-intestinal mucosal damage induced by low-dose aspirin: a prospective randomized clinical trial

K. Higuchi, S. Nouda, T. Kuramoto, 2018, Journal of clinical biochemistry and nutrition.

Drug Delivery with Hyaluronic Acid-Coated Polymeric Micelles in Liver Fibrosis Therapy.

H. Yoshiji, A. Kuzuya, K. Higuchi, 2023, ACS biomaterials science & engineering.

Prevalence of symptomatic gastro‐oesophageal reflux disease in Japanese patients with peptic ulcer disease after eradication of Helicobacter pylori infection

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2004, Alimentary pharmacology & therapeutics.

Current Topics of Strategy of NSAID-Induced Small Intestinal Lesions

K. Higuchi, T. Kuramoto, Takuya Inoue, 2015, Digestion.

Expression of 4C8 antigen, a novel transendothelial migration‐associated molecule on activated T lymphocytes, in inflammatory bowel disease

N. Oshitani, K. Higuchi, T. Arakawa, 2002, The Journal of pathology.

Antegrade brushing cytology through the EUS-guided pancreatic duct drainage route (with video)

S. Ueno, K. Higuchi, T. Ogura, 2021, Endoscopic ultrasound.

[Morphological investigation of H. pylori and its culture method].

K. Tominaga, Y. Fujiwara, K. Higuchi, 2001, Nihon rinsho. Japanese journal of clinical medicine.

Feasibility, safety, and efficacy of the Stretta procedure in Japanese patients with gastroesophageal reflux disease: first report from Asia

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2007, Journal of Gastroenterology.

Comparative analysis of host responses related to immunosuppression between measles patients and vaccine recipients with live attenuated measles vaccines

K. Higuchi, N. Okabe, T. Tsuchiya, 2001, Archives of Virology.

Vonoprazan versus proton‐pump inhibitors for healing gastroesophageal reflux disease: A systematic review

T. Tango, K. Higuchi, T. Takeuchi, 2019, Journal of gastroenterology and hepatology.

Sitagliptin, a dipeptidyl peptidase-4 inhibitor, suppresses CXCL5 and SDF-1 and does not accelerate intestinal neoplasia formation in ApcMin/+ mice fed a high-fat diet.

K. Higuchi, S. Nouda, Takuya Inoue, 2017, Oncology letters.

A Prospective Study Regarding the Efficacy and Safety of the BNT162b2 Vaccine in Patients With Solid Malignancies Undergoing Systemic Chemotherapy

K. Higuchi, A. Ukimura, F. Ono, 2022, In Vivo.

Impact of age at diagnosis of head and neck cancer on incidence of metachronous cancer

N. Uedo, K. Higashino, R. Ishihara, 2019, BMC Cancer.

Monocyte chemotactic protein-1 regulates leukocyte recruitment during gastric ulcer recurrence induced by tumor necrosis factor-alpha.

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2004, American journal of physiology. Gastrointestinal and liver physiology.

Evaluation of the impact of linked color imaging for improving the visibility of colonic polyp.

K. Higuchi, S. Nouda, Takuya Inoue, 2019, Oncology letters.

Lumen-apposing metal stent deployment for walled-off necrosis using semi-free hand technique from the intestine.

K. Higuchi, T. Ogura, N. Nishioka, 2020, Hepatobiliary & pancreatic diseases international : HBPD INT.

Severe Anemia Caused by Gastric Antral Vascular Ectasia and Autoimmune Gastritis

K. Higuchi, Taro Iwatsubo, T. Takeuchi, 2022, Internal medicine.

Sa1431 EVALUATION OF THE SAFETY OF ENDOSCOPIC RADIOFREQUENCY ABLATION FOR MALIGNANT BILIARY STRICTURE USING A DIGITAL PERORAL CHOLANGIOSCOPE

S. Ueno, K. Higuchi, T. Ogura, 2019, Gastrointestinal Endoscopy.

Differential expression of homing receptor CD103 on lamina propria lymphocytes and association of CD103 with epithelial adhesion molecules in inflammatory bowel disease.

Y. Fujiwara, N. Oshitani, K. Higuchi, 2003, International journal of molecular medicine.

Effect of long-term proton pump inhibitor therapy and healing effect of irsogladine on nonsteroidal anti-inflammatory drug-induced small-intestinal lesions in healthy volunteers

K. Higuchi, S. Nouda, T. Kuramoto, 2015, Journal of clinical biochemistry and nutrition.

Dietary intake of vegetables, fruit, and antioxidants and risk of ulcerative colitis: A case-control study in Japan.

K. Sayama, Y. Hiasa, K. Higuchi, 2021, Nutrition (Burbank, Los Angeles County, Calif.).

IL12B rs6887695 polymorphism and interaction with alcohol intake in the risk of ulcerative colitis in Japan.

K. Sayama, Y. Hiasa, K. Higuchi, 2022, Cytokine.

Across-the-papilla side-by-side deployment of three braided stents for malignant hilar biliary obstruction

S. Ueno, K. Higuchi, T. Ogura, 2021, Endoscopy.

Risk Management for Gastrointestinal Endoscopy in Elderly Patients: Questionnaire for Patients Undergoing Gastrointestinal Endoscopy

Kazuhide Higuchi, Shinya Abe, Nozomi Takeuchi, 2009, Journal of clinical biochemistry and nutrition.

Successful treatment for infected biloma after endoscopic ultrasound-guided hepaticogastrostomy using double stent placement technique

K. Higuchi, T. Ogura, Akira Miyano, 2018 .

EUS‐guided antegrade biopsy for lower bile duct obstruction using novel biopsy device with tract dilatation system (with video)

K. Higuchi, T. Ogura, Yoshitaro Yamamoto, 2021, Journal of hepato-biliary-pancreatic sciences.

Towards an Interpretation of Intestinal Motility Using Capsule Endoscopy Image Sequences

Yasushi Yagi, Ryusuke Sagawa, Hai Vu, 2009, PSIVT.

Causal effect of anxiety and depression status on the symptoms of gastroesophageal reflux disease and functional dyspepsia during proton pump inhibitor therapy

K. Haruma, A. Oshio, K. Higuchi, 2022, Esophagus.

Clinical Questions and Answers on Gastrointestinal Endoscopy during the Novel Coronavirus Disease 2019 pandemic

H. Ogata, H. Tajiri, H. Inoue, 2020, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Splenic artery aneurysm masquerading as a pancreatic tumor – diagnosis by contrast-enhanced endoscopic ultrasound

K. Higuchi, Y. Kurisu, E. Umegaki, 2012, Endoscopy.

Bile aspiration cytology in diagnosis of bile duct carcinoma: factors associated with positive yields

K. Higuchi, Y. Kurisu, R. Ashida, 2012, Journal of hepato-biliary-pancreatic sciences.

Omnidirectional Vision Attachment for Medical Endoscopes

Yasushi Yagi, Ryusuke Sagawa, Tomio Echigo, 2008 .

Clinical characteristics of elderly patients with proton pump inhibitor-refractory non-erosive reflux disease from the G-PRIDE study who responded to rikkunshito

K. Haruma, H. Kusunoki, K. Murakami, 2014, BMC Gastroenterology.

Observation of the East-West Anisotropy of the Atmospheric Neutrino Flux

S. Kim, E. Blaufuss, G. Sullivan, 1999 .

Front & Back Matter

Y. Imai, K. Chayama, Furhawn A. Shah, 2013, Digestion.

Lafutidine can improve the quality of gastric ulcer healing in humans: a randomized, controlled, multicenter trial

K. Tominaga, Y. Fujiwara, N. Oshitani, 2006, InflammoPharmacology.

A Prospective Trial Comparing Wireless Capsule Endoscopy and Double-Balloon Enteroscopy in Patients with Obscure Gastrointestinal Bleeding

Masatsugu Shiba, Kazuhide Higuchi, Tetsuo Arakawa, 2006 .

Therapy of GERD and FD overlap with symptoms after usual-dose PPI: acotiamide plus usual-dose PPI vs. double-dose PPI

K. Tominaga, K. Higuchi, M. Kusano, 2017 .

Preventive effect of irsogladine or omeprazole on non-steroidal anti-inflammatory drug-induced esophagitis, peptic ulcers, and small intestinal lesions in humans, a prospective randomized controlled study

K. Higuchi, T. Kuramoto, Takuya Inoue, 2013, BMC Gastroenterology.

POTENTIAL OF AUTOFLUORESCENCE COLONOSCOPY FOR PATIENTS WITH ULCERATIVE COLITIS

N. Oshitani, K. Higuchi, T. Arakawa, 2007 .

ENDOLUMINAL THERAPIES FOR REFLUX ESOPHAGITIS

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2006 .

Sleep Disturbances and Refractory Gastroesophageal Reflux Disease Symptoms in Patients Receiving Once-Daily Proton Pump Inhibitors and Efficacy of Twice-Daily Rabeprazole Treatment

Y. Fujiwara, K. Higuchi, T. Arakawa, 2013, Digestion.

Sarcopenia, frailty and type 2 diabetes mellitus (Review).

K. Higuchi, A. Asai, S. Nishiguchi, 2021, Molecular medicine reports.

[Examination of distribution of Helicobacter pylori on gastric mucosa using dye endoscopy].

K. Higuchi, T. Arakawa, H. Sato, 1990, Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology.

A case of acute pancreatitis complicating acute fatty liver of pregnancy

K. Higuchi, R. Ashida, A. Fukuda, 2011 .

The dipeptidyl peptidase-4 inhibitor sitagliptin suppresses mouse colon tumorigenesis in type 2 diabetic mice.

K. Higuchi, S. Nouda, Takuya Inoue, 2016, Oncology reports.

Prospective comparison study of Franseen needle and standard needle use for pancreatic lesions under EUS guidance

K. Higuchi, Y. Kurisu, T. Ogura, 2019, Endoscopic Ultrasound.

Elevated O-GlcNAcylation stabilizes FOXM1 by its reduced degradation through GSK-3β inactivation in a human gastric carcinoma cell line, MKN45 cells.

K. Higuchi, Kazumasa Moriwaki, T. Takeuchi, 2018, Biochemical and biophysical research communications.

Correction to: Proton pump inhibitor monotherapy is effective to attenuate dyspepsia symptoms associated with gastroesophageal reflux disease: a multicenter prospective observational study

K. Haruma, T. Joh, K. Higuchi, 2019, Journal of Gastroenterology.

Investigation of the clinical significance and pathological features of lanthanum deposition in the gastric mucosa

K. Higuchi, Taro Iwatsubo, T. Takeuchi, 2020, BMC Gastroenterology.

[Extraintestinal complications in patients with ulcerative colitis].

N. Oshitani, K. Higuchi, T. Arakawa, 2005, Nihon rinsho. Japanese journal of clinical medicine.

Clinical trial of autologous adipose tissue-derived regenerative (stem) cells therapy for exploration of its safety and efficacy

M. Honda, S. Kaneko, K. Harada, 2021, Regenerative therapy.

Eradication therapy of Helicobacter pylori directly induces apoptosis in inflammation-related immunocytes in the gastric mucosa--possible mechanism for cure of peptic ulcer disease and MALT lymphoma with a low-grade malignancy.

K. Higuchi, T. Arakawa, T. Ohara, 2003, Hepato-gastroenterology.

High molecular protein of Helicobacter pylori responsible for inhibition of ornithine decarboxylase activity of human gastric cultured cells

Y. Yano, K. Tominaga, Y. Fujiwara, 2002, Alimentary pharmacology & therapeutics.

Relationship between peroxisome proliferator-activated receptor-gamma expression and differentiation of human esophageal squamous cell carcinoma.

E. Sasaki, K. Tominaga, Toshio Watanabe, 2005, Oncology reports.

Usefulness of polyethylene glycol solution with dimethylpolysiloxanes for bowel preparation before capsule endoscopy

K. Higuchi, E. Morita, T. Kuramoto, 2010, Journal of gastroenterology and hepatology.

Chemoresistance-Related Genes Profile in Specimens Obtained By Endoscopic Ultrasound-Guided Fine-Needle Aspiration (EUS-FNA)

M. Fukushima, K. Higuchi, T. Arakawa, 2006 .

Tu1553 Irsogladine, a Gastroprotective Drug, Protects Against NSAID-Induced Esophagitis, Peptic Ulcers, and Small Intestinal Mucosal Damages in Healthy Subjects: A Prospective Randomised Study of Comparison With Omeprazole

K. Higuchi, T. Kuramoto, Takuya Inoue, 2011 .

Gastrointestinal: Intrathoracic upside‐down stomach

Y. Fujiwara, K. Higuchi, T. Arakawa, 2001, Journal of Gastroenterology and Hepatology.

A case of gastric duplication evaluated by gastric emptying scintigraphy

Y. Fujiwara, K. Higuchi, T. Arakawa, 2002, Annals of Nuclear Medicine.

Effects of a novel endoscopic reporting system with voice recognition on the endoscopic procedure time and report preparation time: propensity score matching analysis

K. Higuchi, Taro Iwatsubo, T. Takeuchi, 2021, Journal of Gastroenterology.

A male case of autoimmune hepatitis with a episode of hepatocellular carcinoma after long-period steroid therapy

K. Higuchi, A. Asai, S. Fukunishi, 2013 .

Altered expression of both β-carotene 15,15' monooxygenase and lecithin:retinol acyltransferase in obese Zucker rats.

K. Higuchi, H. Miyazaki, H. Tamai, 2011, Journal of nutritional science and vitaminology.

Histological estimation of the efficacy of endoscopic laser coagulation therapy for diffuse antral vascular ectasia.

K. Tominaga, Y. Fujiwara, K. Higuchi, 2000, European journal of gastroenterology & hepatology.

Unique antmacterial mechanism(S) and in vivo efficacy of novel alkyl quinolone alkaloids against Helicobacter pylori

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2000 .

Evaluation of the clinical efficacy of colon capsule endoscopy in the detection of lesions of the colon: prospective, multicenter, open study.

H. Aihara, H. Tajiri, H. Goto, 2015, Gastrointestinal endoscopy.

What Kind of Capsule Endoscope Is Suitable for a Controllable Self-Propelling Capsule Endoscope? Experimental Study Using a Porcine Stomach Model for Clinical Application (with Videos)

Takuya Inoue, Kazuhide Higuchi, Naotake Ohtsuka, 2015, PloS one.

Clinical impact of recombinant thrombomodulin administration on disseminated intravascular coagulation due to severe acute cholangitis (Recover‐AC study)

M. Takenaka, K. Higuchi, T. Eguchi, 2021, Journal of hepato-biliary-pancreatic sciences.

Antegrade metal stent deployment under endoscopic ultrasound guidance using a novel uncovered metal stent with a fine-gauge stent delivery system

S. Ueno, K. Higuchi, T. Ogura, 2021, Endoscopy.

EUS-guided antegrade metal stent deployment using a novel fully covered metal stent with a fine gauge stent delivery system (with video)

S. Ueno, K. Higuchi, T. Ogura, 2021, Endoscopic ultrasound.

Antegrade stent deployment using a novel, covered metal stent through EUS-guided hepaticogastrostomy (with video)

K. Higuchi, T. Ogura, Nobu Nishioka, 2019, Endoscopic ultrasound.

Endoscopic ultrasound-guided hepaticogastrostomy combined with antegrade stenting using a double bare covered metal stent

K. Higuchi, T. Ogura, Akira Miyano, 2018, Endoscopy.

Simplified reintervention method of EUS-guided hepaticogastrostomy stent obstruction.

K. Higuchi, T. Takeuchi, S. Fukunishi, 2016, Gastrointestinal endoscopy.

Augmented expression of secondary lymphoid tissue chemokine and EBI1 ligand chemokine in Crohn’s disease

N. Oshitani, K. Higuchi, T. Arakawa, 2005, Journal of Clinical Pathology.

Differential Diagnosis of Pancreatobiliary Carcinoma from Autoimmune Pancreatitis-Related Diseases: A Report of Three Cases

K. Higuchi, N. Tanigawa, M. Tsuji, 2011, Journal of Gastrointestinal Cancer.

Endoscopic hemostasis for tumor bleeding using intraductal radiofrequency ablation

S. Ueno, K. Higuchi, T. Takeuchi, 2016, Endoscopy.

Relationship between Chemotherapy-Induced Diarrhea and Intestinal Microbiome Composition.

K. Higuchi, T. Takeuchi, K. Ota, 2023, Digestion.

Outcomes of endoscopic submucosal dissection for gastroesophageal reflux disease (ESD-G) for medication-refractory gastroesophageal reflux disease: 35 cases underwent ESD-G including 15 cases followed more than 5 years

K. Higuchi, Taro Iwatsubo, T. Takeuchi, 2021, BMC Gastroenterology.

Post Helicobacter pylori Gastric Diseases

K. Tominaga, K. Higuchi, 2019, Alcoholic/Non-Alcoholic Digestive Diseases.

Clinical Impact of Recombinant Soluble Thrombomodulin for Disseminated Intravascular Coagulation Associated with Severe Acute Cholangitis

K. Higuchi, T. Ogura, Akira Miyano, 2018, Gut and liver.

Slow‐wave photic stimulation relieves patient discomfort during esophagogastroduodenoscopy

Tsutomu Nomura, Kazuhide Higuchi, Tetsuo Arakawa, 2006, Journal of gastroenterology and hepatology.

Down-regulation of collagen I biosynthesis in intestinal epithelial cells exposed to indomethacin: a comparative proteome analysis.

H. Hayashi, K. Higuchi, Akiko Sakai, 2014, Journal of proteomics.

Endoscopic diagnosis of Whipple disease in a patient without gastrointestinal symptoms: A case report

K. Higuchi, T. Takeuchi, Yuki Hirata, 2021, DEN open.

M2b Monocytes Provoke Bacterial Pneumonia and Gut Bacteria–Associated Sepsis in Alcoholics

Sumihiro Suzuki, Makiko Kobayashi, K. Higuchi, 2015, The Journal of Immunology.

Differential expression of vasoactive intestinal peptide receptor 1 expression in inflammatory bowel disease.

N. Oshitani, K. Higuchi, T. Arakawa, 2007, International journal of molecular medicine.

Small bowel injury by low-dose enteric-coated aspirin and treatment with misoprostol: a pilot study.

K. Tominaga, Toshio Watanabe, Y. Fujiwara, 2008, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Co-Administration of Saireito Enabled the Withdrawal of Corticosteroids in an Elderly Woman with Autoimmune Hepatitis.

K. Higuchi, A. Asai, S. Fukunishi, 2016, Internal medicine.

[Gastrointestinal lesions in liver cirrhosis].

Y. Fujiwara, K. Higuchi, T. Arakawa, 1998, Nihon rinsho. Japanese journal of clinical medicine.

Measurement of radon concentrations at Super-Kamiokande

B. Viren, L. R. Sulak, Yugo Kanaya, 1999 .

Retraction Note: Novel Therapeutic Approach Using Drug-loaded Adipose-derived Stem Cells for Pancreatic Cancer

M. Aoki, K. Higuchi, M. Goto, 2021, Scientific Reports.

Successful digital cholangioscopy removal of a stent-retriever tip migrated into the periphery of the bile duct

K. Higuchi, T. Ogura, Akira Miyano, 2018, Endoscopy.

One-step stent deployment of EUS-guided hepaticogastrostomy using a novel covered metal stent with a fine-gauge stent delivery system (with video)

K. Higuchi, T. Ogura, M. Yamada, 2020, Endoscopic ultrasound.