D. Wojciechowicz

发表

Synthesis and evaluation of 4-anilino-6,7-dialkoxy-3-quinolinecarbonitriles as inhibitors of kinases of the Ras-MAPK signaling cascade.

D. Boschelli, D. Berger, M. Dutia, 2003, Bioorganic & medicinal chemistry letters.

4-Anilino-7-alkenylquinoline-3-carbonitriles as potent MEK1 kinase inhibitors.

D. Berger, M. Dutia, D. Powell, 2008, Bioorganic & medicinal chemistry.

Identification of Pyrazolo[1,5-a]pyrimidine-3-carboxylates as B-Raf Kinase Inhibitors.

D. Wojciechowicz, Steven C. Kim, L. Feldberg, 2009 .

Identification of pyrazolo[1,5-a]pyrimidine-3-carboxylates as B-Raf kinase inhibitors.

D. Wojciechowicz, Steven C. Kim, L. Feldberg, 2009, Bioorganic & medicinal chemistry letters.

Discovery of highly potent and selective type I B-Raf kinase inhibitors.

D. Berger, D. Powell, Nancy Torres, 2009, Bioorganic & medicinal chemistry letters.

Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors.

D. Berger, M. Dutia, D. Powell, 2009, Bioorganic & medicinal chemistry letters.

Hit to lead optimization of pyrazolo[1,5-a]pyrimidines as B-Raf kinase inhibitors.

D. Berger, D. Wojciechowicz, Steven C. Kim, 2009, Bioorganic & medicinal chemistry letters.

Phenylacetate inhibits isoprenoid biosynthesis and suppresses growth of human pancreatic carcinoma.

P. Paty, P. Paty, M. Brennan, 1998, Surgery.

Molecular identity and cellular distribution of advanced glycation endproduct receptors: relationship of p60 to OST-48 and p90 to 80K-H membrane proteins.

Alan W. Stitt, D. Wojciechowicz, H. Vlassara, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Hit to lead optimization of pyrazolo[1,5-a]pyrimidines as B-Raf kinase inhibitors.

D. Berger, D. Wojciechowicz, Steven C. Kim, 2009, Bioorganic & medicinal chemistry letters.

Novel sesterterpenoid and norsesterterpenoid RCE-protease inhibitors isolated from the marine sponge Hippospongia sp.

David E. Williams, R. Andersen, D. Wojciechowicz, 2002 .

Wheatgerm agglutinin-mediated toxicity in pancreatic cancer cells

P. Paty, P. Paty, D. Wojciechowicz, 1999, British Journal of Cancer.

B-Raf kinase inhibitors: hit enrichment through scaffold hopping.

Yongbo Hu, Robert Mallon, Larry Feldberg, 2010, Bioorganic & medicinal chemistry letters.

Identification of Galectin-3 As a High-Affinity Binding Protein for Advanced Glycation End Products (AGE): A New Member of the AGE-Receptor Complex

Yong Ming Li, A. Cerami, D. Wojciechowicz, 1995, Molecular medicine.

α-Agglutinin expression in Saccharomyces cerevisiae

P. Lipke, D. Wojciechowicz, 1989 .

Novel pyrazolopyrimidines as highly potent B-Raf inhibitors.

D. Berger, M. Dutia, D. Powell, 2009, Bioorganic & medicinal chemistry letters.

Beta 1-6 branching of N-linked carbohydrate is associated with K-ras mutation in human colon carcinoma cell lines.

P. Paty, D. Wojciechowicz, P. Park, 1995, Biochemical and biophysical research communications.

Synthesis and evaluation of 4-anilino-6,7-dialkoxy-3-quinolinecarbonitriles as inhibitors of kinases of the Ras-MAPK signaling cascade.

D. Boschelli, D. Berger, M. Dutia, 2003, Bioorganic & medicinal chemistry letters.

A 62-kilodalton tyrosine phosphoprotein constitutively present in primary chronic phase chronic myelogenous leukemia enriched lineage negative blast populations.

B. Clarkson, D. Wojciechowicz, A. Strife, 1994, Leukemia.

Attachment and multiplication, morphology and protein production of human fetal primary liver cells cultured in hormonally defined media

D. Wojciechowicz, J. Tanguay, U. Muller-eberhard, 1988, In Vitro Cellular & Developmental Biology.

Indazolylpyrazolopyrimidine as highly potent B-Raf inhibitors with in vivo activity.

D. Berger, M. Dutia, D. Powell, 2010, Journal of medicinal chemistry.

DNA-binding activity of papillomavirus proteins

D. Wojciechowicz, V. Defendi, R. Mallon, 1987, Journal of virology.

A turbidometric assay for measuring proteins in culture media.

D. Wojciechowicz, U. Muller-eberhard, M. De Falco, 1988, Journal of immunological methods.

Attachment and multiplication, morphology and protein production of human fetal primary liver cells cultured in hormonally defined media

D. Wojciechowicz, J. Tanguay, U. Muller-eberhard, 2007, In Vitro Cellular & Developmental Biology.

Aldisine alkaloids from the Philippine sponge Stylissa massa are potent inhibitors of mitogen-activated protein kinase kinase-1 (MEK-1).

M. K. Harper, C. Ireland, D. Wojciechowicz, 2002, Journal of medicinal chemistry.

Epithelial Tissue Hyperplasia Induced by the RAF Inhibitor PF-04880594 Is Attenuated by a Clinically Well-Tolerated Dose of the MEK Inhibitor PD-0325901

S. Yamazaki, D. Wojciechowicz, S. Bagrodia, 2012, Molecular Cancer Therapeutics.

Cell surface anchorage and ligand-binding domains of the Saccharomyces cerevisiae cell adhesion protein alpha-agglutinin, a member of the immunoglobulin superfamily

P. Lipke, D. Wojciechowicz, C. Lu, 1993, Molecular and cellular biology.

AG alpha 1 is the structural gene for the Saccharomyces cerevisiae alpha-agglutinin, a cell surface glycoprotein involved in cell-cell interactions during mating

P. Lipke, D. Wojciechowicz, J. Kurjan, 1989, Molecular and cellular biology.

CEA is the major PHA-L-reactive glycoprotein in colon carcinoma cell lines and tumors: relationship between K-ras activation and beta1-6 branching of N-linked carbohydrate on CEA.

P. Paty, D. Wojciechowicz, P. Park, 2000, Biochemical and biophysical research communications.

Characterization of lectin resistant cell populations derived from human colon carcinoma: correlation of K-Ras with beta1-6 branching of N-linked carbohydrate and CEA production.

P. Paty, D. Wojciechowicz, R. Mallon, 1999, Biochemical and biophysical research communications.

Phytohemagglutinin-L (PHA-L) lectin surface binding of N-linked beta 1-6 carbohydrate and its relationship to activated mutant ras in human pancreatic cancer cell lines.

P. Paty, P. Paty, D. Wojciechowicz, 1996, Cancer letters.

An enzyme-linked immunosorbent assay for the Raf/MEK1/MAPK signaling cascade.

D. Wojciechowicz, C. Kohler, Steven C. Kim, 2001, Analytical biochemistry.

Structure-based design of isoindoline-1,3-diones and 2,3-dihydrophthalazine-1,4-diones as novel B-Raf inhibitors.

D. Berger, D. Powell, D. Wojciechowicz, 2011, Bioorganic & medicinal chemistry letters.

Identification of 4-anilino-3-quinolinecarbonitrile inhibitors of mitogen-activated protein/extracellular signal-regulated kinase 1 kinase.

D. Berger, D. Powell, Biqi Wu, 2004, Molecular cancer therapeutics.

Wheatgerm agglutinin-mediated toxicity in pancreatic cancer cells.

P. Paty, P. Paty, D. Wojciechowicz, 1999 .

4-Anilino-7-alkenylquinoline-3-carbonitriles as potent MEK1 kinase inhibitors.

D. Berger, M. Dutia, D. Powell, 2008, Bioorganic & Medicinal Chemistry.