Defeng Wu

发表

Role of p38 MAPK in CYP2E1-dependent Arachidonic Acid Toxicity*

Defeng Wu, A. Cederbaum, 2003, The Journal of Biological Chemistry.

Cytochrome P4502E1, oxidative stress, JNK, and autophagy in acute alcohol-induced fatty liver.

Defeng Wu, A. Cederbaum, Xiaodong Wang, 2012, Free radical biology & medicine.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

Synergistic toxicity induced by prolonged glutathione depletion and inhibition of nuclear factor-kappaB signaling in liver cells.

Defeng Wu, A. Cederbaum, J. Jiménez-López, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

Role of Itk signalling in the interaction between influenza A virus and T-cells.

Defeng Wu, Song-Liang Wang, Ji-Long Chen, 2012, The Journal of general virology.

Effect of pyridine on the expression of cytochrome P450 isozymes in primary rat hepatocyte culture

Defeng Wu, A. Cederbaum, S. A. Ramin, 1997, Molecular and Cellular Biochemistry.

Cytochrome P450 2E1 potentiates ethanol induction of hypoxia and HIF-1α in vivo.

Lixia Gan, Defeng Wu, A. Cederbaum, 2013, Free radical biology & medicine.

CYP2E1 Potentiates Ethanol-induction of Hypoxia and HIF-1 α in vivo

Lixia Gan, Defeng Wu, A. Cederbaum, 2013 .

Synergistic toxic interactions between CYP2E1, LPS/TNFα, and JNK/p38 MAP kinase and their implications in alcohol-induced liver injury.

Defeng Wu, A. Cederbaum, Xiaodong Wang, 2015, Advances in experimental medicine and biology.

CYP2E1, oxidative stress and MAPK signaling pathways in alcohol-induced hepatotoxicity

Defeng Wu, A. Cederbaum, Lili Yang, 2014 .

CYP2E1 Sensitizes the Liver to LPS- and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases

Defeng Wu, A. Cederbaum, Xiaodong Wang, 2011, International journal of hepatology.

Cytochrome P4502E1 sensitizes to tumor necrosis factor alpha–induced liver injury through activation of mitogen‐activated protein kinases in mice

Defeng Wu, A. Cederbaum, 2008, Hepatology.

Alcohol steatosis and cytotoxicity: the role of cytochrome P4502E1 and autophagy.

Defeng Wu, A. Cederbaum, Xiaodong Wang, 2012, Free radical biology & medicine.

Development and properties of HepG2 cells that constitutively express CYP2E1.

Defeng Wu, A. Cederbaum, 2008, Methods in molecular biology.

Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells.

Defeng Wu, A. Cederbaum, 2006, American journal of physiology. Gastrointestinal and liver physiology.

Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1.

Defeng Wu, A. Cederbaum, 2005, Toxicology and applied pharmacology.

CYP2E1-Dependent Toxicity and Up-Regulation of Antioxidant Genes

Defeng Wu, A. Cederbaum, N. Nieto, 2001, Journal of Biomedical Science.

CYP2E1-dependent toxicity and up-regulation of antioxidant genes.

Defeng Wu, A. Cederbaum, N. Nieto, 2001 .

Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice.

Defeng Wu, A. Cederbaum, Xiaodong Wang, 2010, Free radical biology & medicine.

Hepatotoxicity mediated by pyrazole (cytochrome P450 2E1) plus tumor necrosis factor alpha treatment occurs in c‐Jun N‐terminal kinase 2−/− but not in c‐Jun N‐terminal kinase 1−/− mice

Defeng Wu, A. Cederbaum, Xiaodong Wang, 2011, Hepatology.

Activation of ASK-1 and downstream MAP kinases in cytochrome P4502E1 potentiated tumor necrosis factor alpha liver injury.

Defeng Wu, A. Cederbaum, 2010, Free radical biology & medicine.

Immunochemical identification and localization of cytochrome P-450HSj isozyme, an enzyme related to nitrosamine metabolism, in human gastric mucosa and gastric carcinoma

X. Pan, Defeng Wu, Yu-Dong Shen, 1989 .

Cyclosporine a protects against arachidonic acid toxicity in rat hepatocytes: Role of CYP2E1 and mitochondria

Defeng Wu, A. Cederbaum, Arthur I. Cederbaum, 2002, Hepatology.

Sulforaphane induces Nrf2 and protects against CYP2E1-dependent binge alcohol-induced liver steatosis.

Jianjun Lin, Defeng Wu, Richard Zhou, 2014, Biochimica et biophysica acta.

Interaction of 1-Hydroxyethyl Radical With Glutathione, Ascorbic Acid and α-Tocopherol

Defeng Wu, A. Cederbaum, D. Stoyanovsky, 1998 .

CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophagy in HepG2 E47 cells.

Defeng Wu, A. Cederbaum, Xiaodong Wang, 2010, Biochemical and biophysical research communications.

Cannabidiol protects liver from binge alcohol-induced steatosis by mechanisms including inhibition of oxidative stress and increase in autophagy.

Defeng Wu, A. Cederbaum, Zhenfeng Zhang, 2014, Free radical biology & medicine.

Nitric oxide donors prevent while the nitric oxide synthase inhibitor L-NAME increases arachidonic acid plus CYP2E1-dependent toxicity.

Defeng Wu, A. Cederbaum, 2006, Toxicology and applied pharmacology.

Ethanol Induction of CYP2A5: Permissive Role for CYP2E1

Defeng Wu, A. Cederbaum, J. Zhuge, 2011, Drug Metabolism and Disposition.

Ethanol Induction of CYP 2 A 5 : Permissive Role for CYP 2 E 1

Defeng Wu, A. Cederbaum, J. Zhuge, 2011 .

Ethanol-induction of Cytochrome P 450 2 A 5 : Permissive Role for CYP 2 E 1

Defeng Wu, A. Cederbaum, J. Zhuge, 2010 .

Role of nitric oxide and nuclear factor-kappaB in the CYP2E1 potentiation of tumor necrosis factor alpha hepatotoxicity in mice.

Defeng Wu, A. Cederbaum, Cijie Xu, 2009, Free radical biology & medicine.

BarA/UvrY differentially regulates prodigiosin biosynthesis and swarming motility in Serratia marcescens FS14.

Y. Wang, Dongqing Xu, Defeng Wu, 2022, Research in microbiology.

An inhibitor of cathepsin K, icariin suppresses cartilage and bone degradation in mice of collagen-induced arthritis.

Yonggang Liu, Defeng Wu, Siguo Liu, 2013, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Increased Cell Proliferation by Various Doses of Xenoestrogen in MFC-7 Cell Through Tyrosine Phosphatase Shp2

Juan Wang, Defeng Wu, Zhaokai Wang, 2015 .

Alcohol, Oxidative Stress, and Free Radical Damage

Defeng Wu, A. Cederbaum, 2003, Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism.

Ethanol Cytotoxicity to a Transfected HepG2 Cell Line Expressing Human Cytochrome P4502E1*

Defeng Wu, A. Cederbaum, D. Wu, 1996, The Journal of Biological Chemistry.

Oxidative Stress and Alcoholic Liver Disease

Defeng Wu, A. Cederbaum, Defeng Wu1, 2009, Seminars in liver disease.

Ethanol and arachidonic acid produce toxicity in hepatocytes from pyrazole-treated rats with high levels of CYP2E1

Defeng Wu, A. Cederbaum, 2004, Molecular and Cellular Biochemistry.

Differential roles for ArcA and ArcB homologues in swarming motility in Serratia marcescens FS14

Dongqing Xu, Defeng Wu, T. Ran, 2018, Antonie van Leeuwenhoek.

Role of oxidative stress in alcohol-induced liver injury

Defeng Wu, A. Cederbaum, Yongke Lu, 2009, Archives of Toxicology.

Presence of functionally active cytochrome P‐450IIE1 in the plasma membrane of rat hepatocytes

Defeng Wu, A. Cederbaum, D. Wu, 1992, Hepatology.

Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1-JNK1 pathway in HepG2 cells.

Defeng Wu, A. Cederbaum, Xiaodong Wang, 2011, Free radical biology & medicine.

Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK☆

Defeng Wu, A. Cederbaum, 2013, Redox biology.

Glutathione Depletion in CYP2E1-Expressing Liver Cells Induces Toxicity Due to the Activation of p38 Mitogen-Activated Protein Kinase and Reduction of Nuclear Factor-κB DNA Binding Activity

Defeng Wu, A. Cederbaum, 2004, Molecular Pharmacology.

Glutathione Depletion in CYP 2 E 1-Expressing Liver Cells Induces Toxicity Due to the Activation of p 38 Mitogen-Activated Protein Kinase and Reduction of Nuclear Factor-B DNA Binding Activity

Defeng Wu, A. Cederbaum, 2004 .

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652

Lee, Duchen, Izzo, 2016 .

Characterization of a novel exported esterase Rv3036c from Mycobacterium tuberculosis.

Defeng Wu, Siguo Liu, H. Pang, 2014, Protein expression and purification.

Oxidative Stress , JNK and Autophagy in Acute Alcohol-induced Fatty Liver

Defeng Wu, A. Cederbaum, Xiaodong Wang, 2013 .

Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1.

Defeng Wu, A. Cederbaum, D. Wu, 2001, Alcoholism, clinical and experimental research.

Ethanol-induced apoptosis to stable HepG2 cell lines expressing human cytochrome P-4502E1.

Defeng Wu, A. Cederbaum, D. Wu, 1999, Alcoholism, clinical and experimental research.

Alcohol steatosis and cytotoxicity: the role of cytochrome P4502E1 and autophagy.

Defeng Wu, A. Cederbaum, Xiaodong Wang, 2012, Free radical biology & medicine.

CYP2E1-dependent toxicity and oxidative stress in HepG2 cells.

Defeng Wu, A. Cederbaum, M. Marí, 2001, Free radical biology & medicine.