P. Abel

发表

Relationship between α1-Adrenergic Receptor-Induced Contraction and Extracellular Signal-Regulated Kinase Activation in the Bovine Inferior Alveolar Artery

W. B. Jeffries, C. Hague, P. Gonzalez-Cabrera, 2002, Journal of Pharmacology and Experimental Therapeutics.

Effects of isoxuprine and nylidrin on adrenoreceptors in rat vas deferens.

P. Abel, K. Minneman, A. Fox, 1985, Journal of autonomic pharmacology.

Respiratory dysfunction progresses with age in Kcna1‐null mice, a model of sudden unexpected death in epilepsy

P. Abel, K. Simeone, T. Simeone, 2018, Epilepsia.

Neuropeptide Y Potentiates Contraction and Inhibits Relaxation of Rabbit Coronary Arteries

P. Abel, C. Han, Chide Han, 1987, Journal of cardiovascular pharmacology.

Neuropeptide γ‐(l‐9)‐Peptide: A Major Product of the Posttranslational Processing of γ‐Preprotachykinin in Rat Tissues

R. Murphy, S. Lovas, P. Abel, 1993 .

Upregulation of RGS2: a new mechanism for pirfenidone amelioration of pulmonary fibrosis

T. Casale, S. Rennard, P. Abel, 2016, Respiratory Research.

1 – Pharmacodynamics: Mechanisms of Drug Action∗

P. Abel, F. Dowd, 2016 .

Regulator of G protein signaling 2 is a key modulator of airway hyperresponsiveness.

T. Casale, P. Abel, R. Panettieri, 2012, The Journal of allergy and clinical immunology.

α‐Adrenoceptor Assays

P. Abel, Neha Jain, 2012, Current protocols in pharmacology.

Effect of IL-13 and IL-13 Mutant (IL-13E13K) on Airway Hyperresponsiveness (AHR) and Airway Smooth Muscle (ASM) In Mice

R. Puri, R. Townley, P. Abel, 2007 .

Identification of upregulated phosphoinositide 3-kinase γ as a target to suppress breast cancer cell migration and invasion.

P. Abel, Yan Xie, Y. Tu, 2013, Biochemical pharmacology.

Vasopressin response in collecting ducts of rats resistant to mineralocorticoid hypertension.

W. B. Jeffries, P. Abel, W. Pettinger, 1991, Hypertension.

Endothelium, vasopressin receptors, and resistance to DOCA-salt hypertension.

W. B. Jeffries, P. Abel, W. Pettinger, 1993, The American journal of physiology.

Tonic Inhibitory Role for cAMP in α1a-Adrenergic Receptor Coupling to Extracellular Signal-Regulated Kinases 1/2

W. B. Jeffries, Lei Xiao, P. Gonzalez-Cabrera, 2002, Journal of Pharmacology and Experimental Therapeutics.

8 – Adrenergic Agonists

P. Abel, M. Piascik, Y. Tu, 2017 .

Relationship of alpha-1 Adrenergic Receptor Occupancy to Tissue Response

P. Abel, K. Minneman, 1987 .

Enhanced release of endothelium-derived relaxing factor in mineralocorticoid hypertension.

W. B. Jeffries, P. Abel, W. Pettinger, 1992, Hypertension.

TGF-β1-induced miR-424 promotes pulmonary myofibroblast differentiation by targeting Slit2 protein expression.

K. Bailey, P. Abel, Yan Xie, 2020, Biochemical pharmacology.

Effect of interleukin 13 on bronchial hyperresponsiveness and the bronchoprotective effect of beta-adrenergic bronchodilators and corticosteroids.

R. Townley, P. Abel, N. Qutna, 2009, Annals of Allergy, Asthma & Immunology.

Upregulated P-Rex1 exacerbates human airway smooth muscle hyperplasia in asthma.

T. Casale, P. Abel, R. Panettieri, 2019, The Journal of allergy and clinical immunology.

Effect of IL-1β and TNF-α vs IL-13 on bronchial hyperresponsiveness, β2-adrenergic responses and cellularity of bronchial alveolar lavage fluid.

R. Townley, P. Abel, M. Horiba, 2011, Autonomic & autacoid pharmacology.

KMT5B is required for early motor development

P. Abel, H. Stessman, E. Bredahl, 2022, Frontiers in Genetics.

N‐terminal bis‐(2‐Chloroethyl)amino and Fluorosulphonyl Analogues of Calcitonin Gene‐Related Peptide(8‐37): Irreversible Antagonists at Calcitonin Gene‐Related Peptide Receptors

P. Abel, D. Smith, M. Hulce, 2007, Chemical biology & drug design.

Functional calcitonin gene-related peptide subtype 2 receptors in porcine coronary arteries are identified as calcitonin gene-related peptide subtype 1 receptors by radioligand binding and reverse transcription-polymerase chain reaction.

W. B. Jeffries, P. Abel, D. Smith, 2001, The Journal of pharmacology and experimental therapeutics.

Limitations in using peptide drugs to characterize calcitonin gene-related peptide receptors.

P. Abel, D. Smith, D. Waugh, 1999, The Journal of pharmacology and experimental therapeutics.

Targeting Phosphoinositide 3-Kinase γ in Airway Smooth Muscle Cells to Suppress Interleukin-13-Induced Mouse Airway Hyperresponsiveness

T. Casale, R. Townley, P. Abel, 2012, Journal of Pharmacology and Experimental Therapeutics.

Phorbol myristate acetate suppresses breast cancer cell growth via down-regulation of P-Rex1 expression

T. Wei, P. Abel, Yan Xie, 2016, Protein & Cell.

5 – Introduction to Autonomic Nervous System Drugs

P. Abel, M. Piascik, 2016 .

TGF- β 1-induced miR-424 promotes pulmonary myofibroblast differentiation by targeting Slit2 protein expression inhibitor into HLFs reduced TGF- β 1-induced expression of classic myofibroblast differentiation markers including

K. Bailey, P. Abel, Yan Xie, 2022 .

RGS2 Repression Exacerbates Airway Hyperresponsiveness and Remodeling in Asthma

T. Casale, P. Abel, R. Panettieri, 2015 .

Characterization of the alpha1-adrenoceptor subtype activating extracellular signal-regulated kinase in submandibular gland acinar cells.

M. Bruchas, P. Abel, M. Toews, 2008, European journal of pharmacology.

Characterization of the α 1 -Adrenoceptor Subtype Activating Extracellular Signal-Regulated Kinase in Submandibular Gland Acinar Cells

M. Bruchas, P. Abel, M. Toews, 2008 .

Submandibular Gland Acinar Cells Express Multiple α1-Adrenoceptor Subtypes

M. Bruchas, P. Abel, M. Scofield, 2004, Journal of Pharmacology and Experimental Therapeutics.

Norepinephrine sensitivity and membrane potentials of caudal arterial muscle in DOCA-salt, Dahl, and SHR hypertension in rat.

P. Abel, K. Hermsmeyer, A. Trapani, 1982 .

Heterogeneity of alpha 1-adrenergic receptors revealed by chlorethylclonidine.

P. Abel, K. Minneman, C. Han, 1987, Molecular pharmacology.

Regulation of β-adrenoceptor density and function in rat vas deferens

P. Abel, K. Minneman, J. May, 1986 .

Neuropeptide Y: vasoconstrictor effects and possible role in cerebral vasospasm after experimental subarachnoid hemorrhage

P. Abel, J. Mcdonald, Chide Han, 1988, Brain Research.

Thyroid status and adrenergic receptor subtypes in the rat: comparison of receptor density and responsiveness.

P. Abel, K. Minneman, A. Fox, 1985, The Journal of pharmacology and experimental therapeutics.

Expression of genes encoding antimicrobial and bradykinin-related peptides in skin of the stream brown frog Rana sakuraii

H. Vaudry, P. Abel, J. Leprince, 2007, Peptides.

Vasodilator drug effects on internal mammary artery and saphenous vein grafts.

R. Guyton, P. Abel, C. Hatcher, 1988, Journal of the American College of Cardiology.

DHHC protein‐dependent palmitoylation protects regulator of G‐protein signaling 4 from proteasome degradation

P. Abel, Yan Xie, Y. Tu, 2010, FEBS letters.

Occupancy of alpha 1-adrenergic receptors and contraction of rat vas deferens.

P. Abel, K. Minneman, A. Fox, 1983, Molecular pharmacology.

High efficiency coupling of alpha-1 adrenergic receptors to inositol phospholipid metabolism revealed by denervation of rat vas deferens.

P. Abel, K. Minneman, G. K. Mumford, 1988, The Journal of pharmacology and experimental therapeutics.

Radioligand binding using 125I-labeled peptides.

W. B. Jeffries, P. Abel, D. Waugh, 1997, Methods in molecular biology.

Analysis of data from "cold saturation" radioligand binding experiments.

W. B. Jeffries, P. Abel, D. Waugh, 1997, Methods in molecular biology.

Mitochondrial dynamics regulates migration and invasion of breast cancer cells

Juan Zhang, P. Abel, Youguo Huang, 2012, Oncogene.

Effects of neuropeptide Y on contraction, relaxation, and membrane potential of rabbit cerebral arteries.

P. Abel, C. Han, 1989, Journal of Cardiovascular Pharmacology.

α1Adrenoceptor subtypes linked to different mechanisms for increasing intracellular Ca2+ in smooth muscle

P. Abel, K. Minneman, Chide Han, 1987, Nature.

Progressive cardiorespiratory dysfunction in Kv1.1 knockout mice may provide temporal biomarkers of pending sudden unexpected death in epilepsy (SUDEP): The contribution of orexin

P. Abel, K. Simeone, T. Simeone, 2020, Epilepsia.

Activation of alpha 1-adrenoceptors increases [3H]inositol metabolism in rat vas deferens and caudal artery.

P. Abel, K. Minneman, A. Fox, 1985, European journal of pharmacology.

Solvent effects on coupling yields during rapid solid-phase synthesis of CGRP(8-37) employing in situ neutralization.

P. Abel, D. Smith, M. Hulce, 2008, The journal of peptide research : official journal of the American Peptide Society.

Sympathetic denervation does not alter the density or properties of alpha-1 adrenergic receptors in rat vas deferens.

P. Abel, K. Minneman, T. Martin, 1985, The Journal of pharmacology and experimental therapeutics.

Identification of muscarinic receptor subtypes in mouse parotid gland.

P. Abel, L. Potter, M. Makoid, 1996, The American journal of physiology.

Submandibular gland acinar cells express multiple alpha1-adrenoceptor subtypes.

M. Bruchas, P. Abel, M. Scofield, 2004, The Journal of pharmacology and experimental therapeutics.

Transforming growth factor (TGF)-β1-induced miR-133a inhibits myofibroblast differentiation and pulmonary fibrosis

T. Wei, P. Abel, Yan Xie, 2019, Cell Death & Disease.

TGF‐β1‐induced miR‐424 Mediates Pulmonary Myofibroblast Differentiation via Targeting Slit2

K. Bailey, P. Abel, Yan Xie, 2019, The FASEB Journal.

Up-regulated miR-133a orchestrates epithelial-mesenchymal transition of airway epithelial cells

P. Abel, Linjie Chen, Xiaobai He, 2018, Scientific Reports.

Epigenetic Regulation of Phosphatidylinositol 3,4,5-Triphosphate-dependent Rac Exchanger 1 Gene Expression in Prostate Cancer Cells*

P. Abel, Yan Xie, Y. Tu, 2011, The Journal of Biological Chemistry.

Breast cancer migration and invasion depend on proteasome degradation of regulator of G-protein signaling 4.

T. Wei, P. Abel, Yan Xie, 2009, Cancer research.

Phosphoinositide 3-Kinase γ Regulates Airway Smooth Muscle Contraction by Modulating Calcium Oscillations

T. Casale, P. Abel, Yan Xie, 2010, Journal of Pharmacology and Experimental Therapeutics.

Chronic reserpine treatment alters sensitivity and membrane potential of the rabbit saphenous artery.

P. Abel, K. Goto, P. Urquilla, 1981, Journal of Pharmacology and Experimental Therapeutics.

Human alphaCGRP-8-37

P. Abel, C. K. Taylor, 2007 .

H. Vaudry, P. Abel, P. Cosette, 2005, General and comparative endocrinology.

Changes in mechanical events and adenosine 3',5'-monophosphate levels induced by enantiomers of isoproterenol in isolated rat atria and uteri.

G. Amidon, P. Abel, C. Buckner, 1975, The Journal of pharmacology and experimental therapeutics.

Evidence that neuromedin U may regulate gut motility in reptiles but not in mammals.

P. Abel, J. Hicks, J. Conlon, 1989, European journal of pharmacology.

Binding of agonists and antagonists to β-adrenoceptors in rat vas deferens: relationship to functional response

P. Abel, K. Minneman, J. May, 1985, Naunyn-Schmiedeberg's Archives of Pharmacology.

Reserpine-induced postjunctional supersensitivity in rat vas deferens and caudal artery without changes in alpha adrenergic receptors.

P. Abel, K. Minneman, J. Barakeh, 1985, The Journal of pharmacology and experimental therapeutics.

Gβγ Signaling Promotes Breast Cancer Cell Migration and Invasion

P. Abel, Yan Xie, Y. Tu, 2010, Journal of Pharmacology and Experimental Therapeutics.

Alpha-2 adrenoceptor subtype causing nitric oxide-mediated vascular relaxation in rats.

P. Abel, C. Bockman, I. Gonzalez-Cabrera, 1996, The Journal of pharmacology and experimental therapeutics.

High levels of NPY in rabbit cerebrospinal fluid and immunohistochemical analysis of possible sources

P. Abel, J. Mcdonald, Chide Han, 1988, Brain Research.

Isolation, structural characterization and pharmacological activity of dog neuromedin U

P. Abel, J. Conlon, C. Bockman, 1991, Peptides.

Airway relaxation mechanisms and structural basis of osthole for improving lung function in asthma

T. Casale, T. Wei, P. Abel, 2020, Science Signaling.

Studies on the effects of enantiomers of soterenol, trimetoquinol and salbutamol on beta adrenergic receptors of isolated guinea-pig atria and trachea.

P. Abel, C. Buckner, 1974, The Journal of pharmacology and experimental therapeutics.

Epigenetic repression of regulator of G‐protein signaling 2 promotes androgen‐independent prostate cancer cell growth

Z. Gatalica, P. Abel, Yan Xie, 2012, International journal of cancer.

The role of voltage-gated potassium channels in the regulation of mouse uterine contractility

Ryan C Smith, P. Abel, M. E. Bradley, 2007, Reproductive biology and endocrinology : RB&E.

Primary structure and pharmacological activity of a nonapeptide related to neuromedin U isolated from chicken intestine

P. Abel, S. Harvey, J. Conlon, 1991, Peptides.

Comparison of alpha 1-adrenergic receptor subtypes distinguished by chlorethylclonidine and WB 4101.

P. Abel, K. Minneman, C. Han, 1988, Molecular pharmacology.

Drugs of Abuse

P. Abel, C. Bockman, F. Dowd, 2017 .

"Spare" alpha 1-adrenergic receptors and the potency of agonists in rat vas deferens.

P. Abel, K. Minneman, 1984, Molecular pharmacology.

Quantification of steady state expression of mRNA for alpha-1 adrenergic receptor subtypes using reverse transcription and a competitive polymerase chain reaction.

W. B. Jeffries, P. Abel, M. Scofield, 1995, The Journal of pharmacology and experimental therapeutics.

Alpha 1-adrenoceptor subtypes linked to different mechanisms for increasing intracellular Ca2+ in smooth muscle.

P. Abel, K. Minneman, C. Han, 1987, Nature.

Alpha-1 adrenergic receptor binding and contraction of rat caudal artery.

P. Abel, K. Minneman, 1986, The Journal of pharmacology and experimental therapeutics.

Relationship between α1-adrenoreceptor density and functional response of rat vas deferens

P. Abel, K. Minneman, 1984, Naunyn-Schmiedeberg's Archives of Pharmacology.

9 – Adrenergic Antagonists

P. Abel, M. Piascik, 2017 .

Differential actions of lamprey peptide methionine-tyrosine at Y1 and Y2 neuropeptide Y receptors

P. Abel, J. Conlon, J. Porter, 1994, Regulatory Peptides.

Regional distribution of alpha 1-adrenoceptor subtypes in rat kidney.

W. B. Jeffries, P. Abel, W. Pettinger, 1991, The Journal of pharmacology and experimental therapeutics.

β1- andβ2-adrenoceptor binding and functional response in right and left atria of rat heart

P. Abel, K. Minneman, Kenneth P. Minneman, 1985, Naunyn-Schmiedeberg's Archives of Pharmacology.

Pharmacological Characterization of Novel α-Calcitonin Gene-Related Peptide (CGRP) Receptor Peptide Antagonists That Are Selective for Human CGRP Receptors

P. Abel, D. Smith, M. Hulce, 2006, Journal of Pharmacology and Experimental Therapeutics.

Binding and functional characterization of alpha-2 adrenergic receptor subtypes on pig vascular endothelium.

W. B. Jeffries, P. Abel, C. Bockman, 1993, The Journal of pharmacology and experimental therapeutics.

Heterogeneous expression of alpha 1-adrenoceptor subtypes among rat nephron segments.

W. B. Jeffries, P. Abel, M. Scofield, 1993, Molecular pharmacology.

Effects of trout endothelin on the motility of gastrointestinal smooth muscle from the trout and rat.

P. Abel, J. Conlon, S. Holmgren, 2001, General and Comparative Endocrinology.

Results Increased Drp 1 protein levels in human invasive breast carcinomas and metastases to lymph nodes

Juan Zhang, P. Abel, Youguo Huang, 2016 .

Inhibition of human internal mammary artery contractions. An in vitro study of vasodilators.

R. Guyton, P. Abel, C. Hatcher, 1992, The Journal of thoracic and cardiovascular surgery.

Phorbol myristate acetate suppresses breast cancer cell growth via down-regulation of P-Rex1 expression

T. Wei, P. Abel, Yan Xie, 2016, Protein & Cell.

Neuropeptide gamma-(1-9)-peptide: a major product of the posttranslational processing of gamma-preprotachykinin in rat tissues.

R. Murphy, S. Lovas, P. Abel, 1993, Journal of neurochemistry.

Regulator of G-protein signaling 2 repression exacerbates airway hyper-responsiveness and remodeling in asthma.

T. Casale, P. Abel, R. Panettieri, 2014, American journal of respiratory cell and molecular biology.

Membrane Electrical Mechanism of Basilar Artery Constriction and Pial Artery Dilation by Norepinephrine

P. Abel, D. Harder, K. Hermsmeyer, 1981, Circulation research.

Synthesis and biological activity of C-terminally truncated fragments of human alpha-calcitonin gene-related peptide.

R. Murphy, T. Adrian, P. Abel, 1993, Journal of medicinal chemistry.

G{beta}{gamma} signaling promotes breast cancer cell migration and invasion

P. Abel, Yan Xie, Y. Tu, 2010 .

Purification and characterization of antimicrobial and vasorelaxant peptides from skin extracts and skin secretions of the North American pig frog Rana grylio

P. Abel, F. Knoop, J. Conlon, 2000, Regulatory Peptides.

Trophic Effect of Norepinephrine on the Rat Portal Vein in Organ Culture

P. Abel, K. Hermsmeyer, A. Trapani, 1980, Circulation research.

T helper 17 cells and corticosteroid insensitivity in severe asthma.

T. Casale, P. Abel, Yan Xie, 2021, The Journal of allergy and clinical immunology.

Relationship between alpha 1-adrenoceptor density and functional response of rat vas deferens. Studies with phenoxybenzamine.

P. Abel, K. Minneman, 1984, Naunyn-Schmiedeberg's archives of pharmacology.

Unaltered membrane properties of arterial muscle in Dahl strain genetic hypertension.

F. D. Ingram, N. Matsuki, P. Abel, 1981, The American journal of physiology.

Sympathetic Cross‐Innervation of SHR and Genetic Controls Suggests a Trophic Influence on Vascular Muscle Membranes

P. Abel, K. Hermsmeyer, KENT HERMSMEYER, 1981, Circulation research.

Vasopressin receptor mediated contraction and [3H]inositol metabolism in rat tail artery.

P. Abel, A. Fox, P. Friedman, 1987, European journal of pharmacology.

Modifications to the N-terminus but not the C-terminus of calcitonin gene-related peptide(8-37) produce antagonists with increased affinity.

P. Abel, D. Smith, M. Hulce, 2003, Journal of medicinal chemistry.

Up-regulated miR-133a orchestrates epithelial-mesenchymal transition of airway epithelial cells

P. Abel, Linjie Chen, Xiaobai He, 2018, Scientific Reports.

Role of conformational constraints of position 7 of the disulphide bridge of h-alpha-CGRP derivatives in their agonist versus antagonist properties.

P. Abel, D. Smith, S. Saha, 2009, The journal of peptide research : official journal of the American Peptide Society.

Pharmacological properties of serotonin receptor subtypes mediating contraction of bovine inferior alveolar arteries.

P. Abel, H. O’Donohue, C. Bockman, 2004, Archives of oral biology.

Effect of interleukin 13 on bronchial hyperresponsiveness and the bronchoprotective effect of beta-adrenergic bronchodilators and corticosteroids.

R. Townley, P. Abel, N. Qutna, 2009, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Identification of upregulated phosphoinositide 3-kinase γ as a target to suppress breast cancer cell migration and invasion.

P. Abel, Yan Xie, Y. Tu, 2013, Biochemical pharmacology.

Reproductive Biology and Endocrinology Open Access the Role of Voltage-gated Potassium Channels in the Regulation of Mouse Uterine Contractility

Ryan C Smith, P. Abel, M. E. Bradley, 2022 .

G (cid:1)(cid:2) Signaling Promotes Breast Cancer Cell Migration and Invasion

P. Abel, Yan Xie, Y. Tu, 2010 .

G (cid:1)(cid:2) Signaling Promotes Breast Cancer Cell Migration and Invasion

P. Abel, Yan Xie, Y. Tu, 2010 .

Breast cancer migration and invasion depend on proteasome degradation of regulator of G-protein signaling 4.

T. Wei, P. Abel, Yan Xie, 2009, Cancer research.

Beta 1- and beta 2-adrenoceptor binding and functional response in right and left atria of rat heart.

P. Abel, K. Minneman, E. N. Juberg, 1985, Naunyn-Schmiedeberg's archives of pharmacology.