D. Boyd

发表

Downregulation of MMP-9 in ERK-mutated stable transfectants inhibits glioma invasion in vitro

C. Gondi, D. Dinh, M. Gujrati, 2002, Oncogene.

Regulation of BAD phosphorylation at serine 112 by the Ras-mitogen-activated protein kinase pathway

G. Mills, R. Bast, M. Mao, 1999, Oncogene.

Douglas Boyd, D. Boyd, 1996, Cancer and Metastasis Reviews.

Effect of PD 098059, a specific inhibitor of mitogen-activated protein kinase kinase, on urokinase expression and in vitro invasion.

G. Nicolson, D. Boyd, C. Simon, 1996, Cancer research.

Regulation of urokinase‐type plasminogen activator expression by an ERK1‐dependent signaling pathway in a squamous cell carcinoma cell line

E. Lengyel, D. Boyd, J. Juarez, 1996, Journal of cellular biochemistry.

A region between -141 and -61 bp containing a proximal AP-1 is essential for constitutive expression of urokinase-type plasminogen activator receptor.

H. Allgayer, D. Boyd, H. Wang, 1999, European journal of biochemistry.

Stimulation of urokinase expression by TNF-alpha requires the activation of binding sites for the AP-1 and PEA3 transcription factors.

E. Lengyel, D. Boyd, J. Klostergaard, 1995, Biochimica et biophysica acta.

Involvement of a Mitogen-activated Protein Kinase Signaling Pathway in the Regulation of Urokinase Promoter Activity by c-Ha-ras(*)

E. Lengyel, D. Boyd, R. Gum, 1995, The Journal of Biological Chemistry.

ATF3 Represses 72-kDa Type IV Collagenase (MMP-2) Expression by Antagonizing p53-dependent trans-Activation of the Collagenase Promoter*

D. Boyd, Chunhong Yan, Heng Wang, 2002, The Journal of Biological Chemistry.

The Kruppel-like KLF4 Transcription Factor, a Novel Regulator of Urokinase Receptor Expression, Drives Synthesis of This Binding Site in Colonic Crypt Luminal Surface Epithelial Cells*

D. Boyd, M. S. Jamaluddin, Heng Wang, 2004, Journal of Biological Chemistry.

An orthotopic floor‐of‐mouth cancer model allows quantification of tumor invasion

C. Flaitz, D. Boyd, C. Simon, 1998, The Laryngoscope.

Gene expression profiling identifies activating transcription factor 3 as a novel contributor to the proapoptotic effect of curcumin.

J. Myers, D. Boyd, Chunhong Yan, 2005, Molecular cancer therapeutics.

An inhibitor of c-jun aminoterminal kinase (SP600125) represses c-Jun activation, DNA-binding and PMA-inducible 92-kDa type IV collagenase expression.

D. Boyd, M. Shin, C. Yan, 2002, Biochimica et biophysica acta.

Transgenic mice demonstrate novel promoter regions for tissue-specific expression of the urokinase receptor gene.

D. Boyd, Chunhong Yan, Yao Wang, 2003, The American journal of pathology.

CANCER C ELL H EPARANASE ACTIVITY A SSOCIATED W ITH INVASION A ND METASTASIS

G. Nicolson, D. Boyd, H. Wakabayashi, 1998 .

Cancer cell heparanase activity associated with invasion and metastasis.

T. Irimura, G. Nicolson, M. Nakajima, 1998, Advances in enzyme regulation.

PD 098059, an inhibitor of ERK1 activation, attenuates the in vivo invasiveness of head and neck squamous cell carcinoma

C. Flaitz, D. Boyd, C. Simon, 1999, British Journal of Cancer.

Identification of an histone H3 acetylated/K4-methylated-bound intragenic enhancer regulatory for urokinase receptor expression

H. Allgayer, I. Asangani, D. Boyd, 2007, Oncogene.

Elevated urokinase-type plasminogen activator receptor expression in a colon cancer cell line is due to a constitutively activated extracellular signal-regulated kinase-1-dependent signaling cascade

E. Lengyel, Y. Wang, D. Boyd, 1997, Oncogene.

Modulation of in vitro invasion of human glioblastoma cells by urokinase-type plasminogen activator receptor antibody.

F. Ali-Osman, S. Mohanam, J. S. Rao, 1993, Cancer research.

Identification of a novel nuclear factor-kappaB sequence involved in expression of urokinase-type plasminogen activator receptor.

H. Allgayer, G. Murrell, D. Boyd, 2000, European journal of biochemistry.

Characterization of the retinol and retinoic acid binding proteins in the human prostate.

F. Habib, D. Boyd, G. Chisholm, 1984, Cancer research.

In vitro inhibition of human glioblastoma cell line invasiveness by antisense uPA receptor

Z. Gokaslan, S. Mohanam, J. S. Rao, 1997, Oncogene.

A comparison of retinol binding in human hyperplastic and malignant prostate.

F. Habib, D. Boyd, G. Chisholm, 1985, British Journal of Cancer.

Urokinase-type Plasminogen Activator Receptor Antibody Invasion of Human Glioblastoma Cells by in Vitro Modulation of Updated

F. Ali-Osman, S. Mohanam, J. S. Rao, 2006 .

Characterization of the Retino! and Retinoic Acid Binding Proteins in the Human Prostate1

F. Habib, D. Boyd, G. Chisholm, 2006 .

Regulation of urokinase‐type plasminogen activator expression in squamous‐cell carcinoma of the oral cavity

G. Nicolson, G. Clayman, A. Mazar, 1993, International journal of cancer.

Divergent effect of n,n-dimethylformamide on the expression of urokinase and its receptor

A. Mazar, J. Henkin, D. Boyd, 1993 .

Insulin receptors with defective tyrosine kinase inhibit normal receptor function at the level of substrate phosphorylation.

A. Ullrich, J. Olefsky, H. Maegawa, 1988, The Journal of biological chemistry.

Role and regulation of expression of 92‐kDa type‐IV collagenase (MMP‐9) in 2 invasive squamous‐cell‐carcinoma cell lines of the oral cavity

G. Nicolson, H. Saya, G. Clayman, 1993, International journal of cancer.

Regulation of the Urokinase Receptor by Its Plasminogen Activator

D. Boyd, W. Hollas, 1991, Thrombosis and Haemostasis.

Urokinase-Dependent Proteolysis in Cultured Colon Cancer Is Directed by Its Receptor

D. Boyd, W. Hollas, 1991, Seminars in thrombosis and hemostasis.

Stimulation of urokinase-type plasminogen activator receptor expression by PMA requires JNK1-dependent and -independent signaling modules

H. Allgayer, A. Mazar, Y. Wang, 1998, Oncogene.

Tumor-specific transcription factor binding to an activator protein-2/Sp1 element of the urokinase-type plasminogen activator receptor promoter in a first large series of resected gastrointestinal cancers.

H. Allgayer, E. Lengyel, F. Schildberg, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Transcriptional Induction of the Urokinase Receptor Gene by a Constitutively Active Src

H. Allgayer, Hong Wang, A. Kraker, 1999, The Journal of Biological Chemistry.

Role of the urokinase receptor in facilitating extracellular matrix invasion by cultured colon cancer.

D. Boyd, F. Blasi, W. Hollas, 1991, Cancer research.

Requirement of an Upstream AP-1 Motif for the Constitutive and Phorbol Ester-inducible Expression of the Urokinase-type Plasminogen Activator Receptor Gene*

D. Boyd, W. Doe, C. Pfarr, 1996, The Journal of Biological Chemistry.

Combination of an Src Kinase Inhibitor with a Novel Pharmacological Antagonist of the Urokinase Receptor Diminishes in Vitro Colon Cancer Invasiveness

H. Kessler, D. Boyd, G. Gallick, 2004, Clinical Cancer Research.

Transcriptional activation of the urokinase receptor gene in invasive colon cancer

J. Skibber, D. Boyd, J. Juarez, 1994, International journal of cancer.

Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor.

B. Aggarwal, Y. Takada, X. Fang, 2004, The Journal of biological chemistry.

Regulation of the urokinase-type plasminogen activator receptor gene in different grades of human glioma cell lines.

S. Mohanam, J. S. Rao, S. Lakka, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Regulation of 92 kDa type IV collagenase expression by the jun aminoterminal kinase- and the extracellular signal-regulated kinase-dependent signaling cascades

E. Lengyel, D. Boyd, J. Juarez, 1997, Oncogene.

Expression cloning of novel regulators of 92 kDa type IV collagenase expression.

R. Nair, D. Boyd, 2005, Biochemical Society transactions.

Organ-site dependence for the production of urokinase-type plasminogen activator and metastasis by human renal cell carcinoma cells.

C. Bucana, C. Dinney, I. Fidler, 1997, The American journal of pathology.

Mechanisms of invasion by head and neck cancers.

G. Nicolson, D. Boyd, 1995, Cancer treatment and research.

Induction of M(r) 92,000 type IV collagenase expression in a squamous cell carcinoma cell line by fibroblasts.

E. Lengyel, G. Clayman, H. Sato, 1995, Cancer research.

Involvement of urokinase and its receptor in the invasiveness of human prostatic carcinoma cell lines.

A. Mazar, J. Henkin, D. Boyd, 1991, Cancer communications.

Transcriptional Control of Proteases

H. Allgayer, E. Lengyel, D. Boyd, 2002 .

Stimulation of 92-kDa Gelatinase B Promoter Activity by ras Is Mitogen-activated Protein Kinase Kinase 1-independent and Requires Multiple Transcription Factor Binding Sites Including Closely Spaced PEA3/ets and AP-1 Sequences (*)

E. Lengyel, H. Sato, D. Boyd, 1996, The Journal of Biological Chemistry.

KiSS-1 represses 92-kDa type IV collagenase expression by down-regulating NF-kappa B binding to the promoter as a consequence of Ikappa Balpha -induced block of p65/p50 nuclear translocation.

D. Boyd, H. Wang, C. Yan, 2001, The Journal of biological chemistry.

Regulation of matrix metalloproteinase gene expression

D. Boyd, Chunhong Yan, 2007, Journal of cellular physiology.

KiSS-1 Represses 92-kDa Type IV Collagenase Expression by Down-regulating NF-κB Binding to the Promoter as a Consequence of IκBα-induced Block of p65/p50 Nuclear Translocation*

D. Boyd, Chunhong Yan, Heng Wang, 2001, The Journal of Biological Chemistry.

Measurement of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Blood and Tissues: Clinical and Experimental Applications

L. Matrisian, G. Nicolson, D. Boyd, 1999, Annals of the New York Academy of Sciences.

Targeting of urokinase plasminogen activator receptor in human pancreatic carcinoma cells inhibits c-Met- and insulin-like growth factor-I receptor-mediated migration and invasion and orthotopic tumor growth in mice.

L. Ellis, Wenbiao Liu, F. Fan, 2005, Cancer research.

ZKSCAN3 is a master transcriptional repressor of autophagy.

A. Kamat, D. Boyd, S. Chauhan, 2013, Molecular cell.

The previously undescribed ZKSCAN3 (ZNF306) is a novel "driver" of colorectal cancer progression.

Douglas D Boyd, Stanley R Hamilton, Lin Yang, 2008, Cancer research.

A novel function of caspase‐8 in the regulation of androgen‐receptor‐driven gene expression

Zhengxin Wang, Hong Wu, D. Boyd, 2007, EMBO Journal.

Inducible changes in cell size and attachment area due to expression of a mutant SWI/SNF chromatin remodeling enzyme

Simion I. Chiosea, A. Fischer, S. Chiosea, 2004, Journal of Cell Science.

Unbiased Screening for Transcriptional Targets of ZKSCAN3 Identifies Integrin β4 and Vascular Endothelial Growth Factor as Downstream Targets*

Douglas D Boyd, Li Zhang, Lin Yang, 2008, Journal of Biological Chemistry.

Histone H3 Acetylation and H3 K4 Methylation Define Distinct Chromatin Regions Permissive for Transgene Expression

Douglas D. Boyd, D. Boyd, Chunhong Yan, 2006, Molecular and Cellular Biology.

A novel homologous recombination system to study 92 kDa type IV collagenase transcription demonstrates that the NFκB motif drives the transition from a repressed to an activated state of gene expression

B. Aggarwal, D. Boyd, Chunhong Yan, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Role of plasminogen activator and of 92-KDa type IV collagenase in glioblastoma invasion using anin vitro Matrigel model

L. Liotta, W. Stetler-Stevenson, F. Ali-Osman, 2005, Journal of Neuro-Oncology.

Genetic Deletion of Glycogen Synthase Kinase-3β Abrogates Activation of IκBα Kinase, JNK, Akt, and p44/p42 MAPK but Potentiates Apoptosis Induced by Tumor Necrosis Factor*

B. Aggarwal, Y. Takada, X. Fang, 2004, Journal of Biological Chemistry.

Gene trapping identifies chloride channel 4 as a novel inducer of colon cancer cell migration, invasion and metastases

D. Boyd, M. Yamamoto, T Ishiguro, 2010, British Journal of Cancer.

A Novel High-Throughput Screening System Identifies a Small Molecule Repressive for Matrix Metalloproteinase-9 Expression

Zhengxin Wang, R. Nair, D. Boyd, 2008, Molecular Pharmacology.

Activating transcription factor 3, a stress sensor, activates p53 by blocking its ubiquitination

Tsonwin Hai, D. Boyd, D. Lu, 2005, The EMBO journal.

MDM2 Mediates Ubiquitination and Degradation of Activating Transcription Factor 3*

Hua Lu, D. Boyd, Hongbo Wang, 2010, The Journal of Biological Chemistry.

Activation of Src kinase in primary colorectal carcinoma

Heike Allgayer, H. Allgayer, S. Curley, 2002, Cancer.

Targeted disruption of the K-Ras oncogene in an invasive colon cancer cell line down-regulates urokinase receptor expression and plasminogen-dependent proteolysis

H. Allgayer, T. Sasazuki, D. Boyd, 1999, British Journal of Cancer.

Transactivation of the Urokinase-type Plasminogen Activator Receptor Gene through a Novel Promoter Motif Bound with an Activator Protein-2α-related Factor*

H. Allgayer, D. Boyd, R. Bauer, 1999, The Journal of Biological Chemistry.

Plasticity in urokinase-type plasminogen activator receptor (uPAR) display in colon cancer yields metastable subpopulations oscillating in cell surface uPAR density--implications in tumor progression.

D. Boyd, J. Trevino, Y. Kitadai, 2006, Cancer research.

Expression Cloning Identifies Transgelin (SM22) as a Novel Repressor of 92-kDa Type IV Collagenase (MMP-9) Expression*

R. Nair, D. Boyd, J. Solway, 2006, Journal of Biological Chemistry.

Accelerated urokinase-receptor protein turnover triggered by interference with the addition of the glycolipid anchor.

Sean M. Hartig, D. Boyd, S. Chauhan, 2011, The Biochemical journal.

Expression of Urokinase and Its Receptor in Invasive and Non-Invasive Prostate Cancer Cell Lines

A. Mazar, J. Henkin, D. Boyd, 1992, Thrombosis and Haemostasis.

Repression of 92-kDa Type IV Collagenase Expression by MTA1 Is Mediated through Direct Interactions with the Promoter via a Mechanism, Which Is Both Dependent on and Independent of Histone Deacetylation*

D. Boyd, Chunhong Yan, Y. Toh, 2003, The Journal of Biological Chemistry.

ATF3 Regulates the Stability of p53: A Link to Cancer

D. Boyd, Chunhong Yan, 2006, Cell cycle.

Regulation of u-PAR gene expression by H2A.Z is modulated by the MEK–ERK/AP-1 pathway

D. Boyd, S. Chauhan, 2011, Nucleic acids research.

Interferons Inhibit Tumor Necrosis Factor-α-mediated Matrix Metalloproteinase-9 Activation via Interferon Regulatory Factor-1 Binding Competition with NF-κB*

B. Bauvois, D. Boyd, M. Seiki, 2002, The Journal of Biological Chemistry.

Regulation of the uPA gene in various grades of human glioma cells.

S. Mohanam, J. S. Rao, S. Lakka, 2001, International journal of oncology.

A urokinase-derived peptide (A6) increases survival of mice bearing orthotopically grown prostate cancer and reduces lymph node metastasis.

D. Boyd, G. Gallick, Sun-jin Kim, 2003, The American journal of pathology.

Inhibition of the p38 mitogen-activated protein kinase by SB 203580 blocks PMA-induced Mr 92,000 type IV collagenase secretion and in vitro invasion.

D. Boyd, C. Simon, H. Goepfert, 1998, Cancer research.

Interferons inhibit tumor necrosis factor-alpha-mediated matrix metalloproteinase-9 activation via interferon regulatory factor-1 binding competition with NF-kappa B.

B. Bauvois, D. Boyd, M. Seiki, 2002, The Journal of biological chemistry.

Up-regulation of urokinase-type plasminogen activator expression by the HER2/neu proto-oncogene.

E. Lengyel, M. Hung, D. Yu, 1995, Anticancer research.

Regulation of urokinase-type plasminogen activator expression by the v-mos oncogene.

A. Sabichi, M. Birrer, D. Boyd, 1995, Oncogene.

Decreased urokinase receptor expression by overexpression of the plasminogen activator in a colon cancer cell line.

A. Mazar, J. Henkin, D. Boyd, 1992, The Biochemical journal.

A bisanthracycline (WP631) represses uPAR gene expression and cell migration of RKO colon cancer cells by interfering with transcription factor binding to a chromatin-accessible -148/-124 promoter region.

R. Nair, D. Boyd, W. Priebe, 2005, Oncology research.

Insensitivity of laminin degradation directed by receptor bound urokinase to PAI-1 in cultured colon cancer.

D. Boyd, D D Boyd, J W Schlechte, 1990, Cancer communications.

Examination of the role of the urokinase receptor in human colon cancer mediated laminin degradation.

D. Boyd, D. Boyd, G. Murano, 1989, Cancer research.

Decoy molecules based on PNA-DNA chimeras and targeting Sp1 transcription factors inhibit the activity of urokinase-type plasminogen activator receptor (uPAR) promoter.

R. Gambari, E. Fabbri, M. Borgatti, 2005, Oncology research.

Examination of the role of the urokinase receptor in human colon cancer mediated laminin degradation.

D. Boyd, G. Murano, Warren Schlechte, 1989, Cancer Research.

ZKSCAN3 is a master transcriptional repressor of autophagy.

A. Kamat, D. Boyd, S. Chauhan, 2013, Molecular cell.

Gene expression profiling identifies activating transcription factor 3 as a novel contributor to the proapoptotic effect of curcumin.

J. Myers, D. Boyd, Chunhong Yan, 2005, Molecular cancer therapeutics.

Involvement of heparanase in tumor metastases: a new target in cancer therapy?

M. Nakajima, D. Boyd, 2004, Journal of the National Cancer Institute.