J. Shih

发表

Activation of Human Monoamine Oxidase B Gene Expression by a Protein Kinase C MAPK Signal Transduction Pathway Involves c-Jun and Egr-1*

W. K. Wong, X. Ou, Kevin S. Chen, 2002, The Journal of Biological Chemistry.

Monoamine oxidase A mediates prostate tumorigenesis and cancer metastasis.

Chun-Peng Liao, L. Chung, B. Stiles, 2014, The Journal of clinical investigation.

Behavioral outcomes of monoamine oxidase deficiency: preclinical and clinical evidence.

J. Shih, M. Bortolato, 2011, International review of neurobiology.

The mouse cortico-striatal projectome

Nicholas N. Foster, Monica Y. Song, Hong-wei Dong, 2016, Nature Neuroscience.

Monoamine oxidase: from genes to behavior.

J. Shih, K. Chen, M. Ridd, 1999, Annual review of neuroscience.

Serotonin Catabolism and the Formation and Fate of 5-Hydroxyindole Thiazolidine Carboxylic Acid*

J. Sweedler, N. Hatcher, Kevin S. Chen, 2006, Journal of Biological Chemistry.

Serotonin2A receptor gene polymorphism in mood disorders

Kevin S. Chen, J. Shih, K. Ohara, 1997, Biological Psychiatry.

Valproic Acid Induces Monoamine Oxidase A via Akt/Forkhead Box O1 Activation

J. Shih, J. Wu, 2011, Molecular Pharmacology.

Glyceraldehyde-3-Phosphate Dehydrogenase–Monoamine Oxidase B-Mediated Cell Death-Induced by Ethanol is Prevented by Rasagiline and 1-R-Aminoindan

G. Rajkowska, M. Youdim, X. Ou, 2009, Neurotoxicity Research.

No association of the MAOA gene with alcoholism among Han Chinese males in Taiwan

H. Ko, Kevin S. Chen, J. Shih, 2002, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

The aggression and behavioral abnormalities associated with monoamine oxidase A deficiency are rescued by acute inhibition of serotonin reuptake.

Kevin S. Chen, J. Shih, M. Bortolato, 2014, Journal of psychiatric research.

Tissue Distribution of Human Monoamine Oxidase A and B mRNA

R. Neve, J. Shih, N. Lan, 1990, Journal of neurochemistry.

Biochemical effects of the monoamine neurotoxins DSP‐4 and MDMA in specific brain regions of MAO‐B‐deficient mice

Kevin S. Chen, J. Shih, F. Fornai, 2001, Synapse.

The circadian rhythm of 5-HT biosynthetic and degradative enzymes in immortalized mouse neuroendocrine pineal cell line--a model for studying circadian rhythm.

Kevin S. Chen, J. Shih, Philip Yeung Lam, 2004, Life Science.

Brain injury and inflammation genes common to a number of neurological diseases and the genes involved in the genesis of GABAnergic neurons are altered in monoamine oxidase B knockout mice

B. Tabakoff, Kevin S. Chen, J. Shih, 2021, Brain Research.

Retinoic Acid Activates Monoamine Oxidase B Promoter in Human Neuronal Cells*

X. Ou, Kevin S. Chen, J. Shih, 2009, The Journal of Biological Chemistry.

Neither antisocial personality disorder nor antisocial alcoholism is associated with the MAO-A gene in Han Chinese males.

H. Ko, J. Shih, R. Lu, 2003, Alcoholism, clinical and experimental research.

Monoamine Oxidases Regulate Telencephalic Neural Progenitors in Late Embryonic and Early Postnatal Development

M. Mattson, J. Cadet, Kevin S. Chen, 2010, The Journal of Neuroscience.

Novel monoamine oxidase A knock out mice with human-like spontaneous mutation

J. Shih, M. Bortolato, A. Scott, 2008, Neuroreport.

Tissue-specific effects of estrogen on monoamine oxidase A and B in the rat.

J. Shih, D. Holschneider, T. Kumazawa, 1998, Life sciences.

Monoamine oxidase A is highly expressed in classical Hodgkin lymphoma

A. Mottok, C. Steidl, Chieh-Hsi Wu, 2017, The Journal of pathology.

Molecular neuroanatomy of human monoamine oxidases A and B revealed by quantitative enzyme radioautography and in situ hybridization histochemistry

P. Malherbe, J. Shih, J. Saura, 1996, Neuroscience.

Monoamine oxidase A and organic cation transporter 3 coordinate intracellular β1AR signaling to calibrate cardiac contractile function

J. Hell, J. Shih, N. Kaludercic, 2022, Basic Research in Cardiology.

Striatal Damage and Oxidative Stress Induced by the Mitochondrial Toxin Malonate Are Reduced in Clorgyline-Treated Rats and MAO-A Deficient Mice

D. Butterfield, K. Young, J. Shih, 2004, Neurochemical Research.

Cerebral cortical blood flow maps are reorganized in MAOB-deficient mice

O. Scremin, J. Shih, D. Holschneider, 1999, Brain Research.

Ginkgo biloba abolishes aggression in mice lacking MAO A.

J. Shih, I. Seif, K. Chen, 2000, Antioxidants & redox signaling.

Ketanserin and tetrabenazine abolish aggression in mice lacking monoamine oxidase A

M. Kung, J. Shih, I. Seif, 1999, Brain Research.

Lack of protection from ischemic injury of monoamine oxidase B-deficient mice following middle cerebral artery occlusion

O. Scremin, J. Shih, D. Holschneider, 1999, Neuroscience Letters.

Molecular Studies of 5‐HT Receptors a

J. Shih, Kevin Chen, 1990, Annals of the New York Academy of Sciences.

Monoamine Oxidase A–Mediated Enhanced Catabolism of Norepinephrine Contributes to Adverse Remodeling and Pump Failure in Hearts With Pressure Overload

D. Kass, R. Blakely, K. Pacak, 2010, Circulation research.

Monoamine oxidase B prompts mitochondrial and cardiac dysfunction in pressure overloaded hearts.

D. Kass, M. Lindsey, K. Pacak, 2014, Antioxidants & redox signaling.

Cloning of a novel monoamine oxidase cDNA from trout liver.

J. Shih, K. Chen, J. Grimsby, 1994, Molecular pharmacology.

Human monoamine oxidase A and B genes exhibit identical exon-intron organization.

J. Shih, N. Lan, K. Chen, 1991, Proceedings of the National Academy of Sciences of the United States of America.

R1, a Novel Repressor of the Human Monoamine Oxidase A*

S. Choi, X. Ou, J. Shih, 2005, Journal of Biological Chemistry.

Adverse Remodeling and Pump Failure in Hearts With Pressure Overload Mediated Enhanced Catabolism of Norepinephrine Contributes to − Monoamine Oxidase

D. Kass, R. Blakely, K. Pacak, 2009 .

Mitochondrial 4-HNE derived from MAO-A promotes mitoCa2+ overload in chronic postischemic cardiac remodeling

F. Lezoualc’h, O. Burlet-Schiltz, J. Shih, 2019, Cell Death & Differentiation.

Gene-environment interactions in antisocial behavior are mediated by early-life 5-HT 2A receptor activation

S. Scheggi, C. Gambarana, B. Wilkinson, 2020 .

Platelet MAO activity in depressed patients

G. Simpson, R. Sloane, J. Shih, 1981 .

Cardiac MAO-A inhibition protects against catecholamine-induced ventricular arrhythmias via enhanced diastolic calcium control

D. Hall, J. Shih, E. Abel, 2022, bioRxiv.

Decreased Methylation and Transcription Repressor Sp3 Up-regulated Human Monoamine Oxidase (MAO) B Expression during Caco-2 Differentiation*

W. K. Wong, J. Shih, Kevin Chen, 2003, Journal of Biological Chemistry.

Deletion of monoamine oxidase A in a prostate cancer model enhances anti-tumor immunity through reduced immune suppression.

J. Shih, A. Epstein, Julie K. Jang, 2022, Biochemical and biophysical research communications.

Yang-gan-wan protects mice against apoptosis induced by anti-Fas antibody (Jo2).

J. Shih, M. Yang, K. Chen, 2000, The American journal of Chinese medicine.

Site-directed mutagenesis of monoamine oxidase A and B: role of cysteines.

J. Shih, H. F. Wu, K. Chen, 1993, Molecular pharmacology.

Neurotransmitter signaling: a new frontier in colorectal cancer biology and treatment

Shannon M. Mumenthaler, H. Lenz, J. Millstein, 2022, Oncogene.

Transcription Factor E2F-Associated Phosphoprotein (EAPP), RAM2/CDCA7L/JPO2 (R1), and Simian Virus 40 Promoter Factor 1 (Sp1) Cooperatively Regulate Glucocorticoid Activation of Monoamine Oxidase B

X. Ou, J. Shih, J. Wu, 2011, Molecular Pharmacology.

Role of MAO A and B in neurotransmitter metabolism and behavior.

J. Shih, M. Ridd, K. Chen, 1999, Polish journal of pharmacology.

Analysis of the pharmacological and molecular heterogeneity of I(2)-imidazoline-binding proteins using monoamine oxidase-deficient mouse models.

J. Shih, A. Parini, I. Seif, 2000, Molecular pharmacology.

Type A monoamine oxidase is the target of an endogenous dopaminergic neurotoxin, N‐methyl(R)salsolinol, leading to apoptosis in SH‐SY5Y cells

Y. Akao, M. Naoi, J. Shih, 2006, Journal of neurochemistry.

Expression of human monoamine oxidase (MAO) A gene controlled by transcription factor Sp1.

J. Shih, Q. Zhu, K. Chen, 1995, Progress in brain research.

Identification of human monoamine oxidase (MAO) A and B gene promoters.

J. Shih, J. Grimsby, Q. Zhu, 1994, Journal of neural transmission. Supplementum.

The Deduced Amino Acid Sequences of Human Platelet and Frontal Cortex Monoamine Oxidase B Are Identical

J. Shih, Kevin Chen, Hsiu‐Fei Wu, 1993, Journal of neurochemistry.

Promoter Organization (MAO) A and B Genes and Activity of Human Monoamine Oxidase

J. Shih, J. Grimsby, Q. Zhu, 1992 .

Interaction of N‐(2‐Nitro‐4‐Azidophenyl)‐Serotonin with Two Types of Monoamine Oxidase in Rat Brain

J. Shih, Shiuan Chen, Qin‐Ping Xu, 1984, Journal of neurochemistry.

Monoamine Oxidases: From Tissue Homogenates to Transgenic Mice

J. Shih, 2007, Neurochemical Research.

Monoamine oxidase gene transcription in human cell lines: Treatment with psychoactive drugs and ethanol

J. Shih, J. Ekblom, Q. Zhu, 2005, Journal of Neural Transmission.

In Vivo and in Vitro Functions of Two Types of Mao

J. Shih, Kevin Chen, 2002 .

Effects of Carboxyl-terminal Truncations on the Activity and Solubility of Human Monoamine Oxidase B*

J. Shih, I. Rebrin, Kevin Chen, 2001, The Journal of Biological Chemistry.

Regulation of human monoamine oxidase B gene by Sp1 and Sp3.

W. K. Wong, J. Shih, K. Chen, 2001, Molecular pharmacology.

Molecular Biology of Monoamine Oxidase A and B: Their Role in the Degradation of Serotonin

J. Shih, J. Grimsby, K. Chen, 2000 .

Striatal Dopamine Metabolism in Monoamine Oxidase B‐Deficient Mice : A Brain Dialysis Study

J. Shih, F. Fornai, F. Giorgi, 1999, Journal of neurochemistry.

Monoamine oxidase A and B: structure, function, and behavior.

J. Shih, K. Chen, K. Chen, 1998, Advances in pharmacology.

Binding of the Imidazoline Ligand3H‐2‐Benzofuranyl‐2‐Imidazoline (BFI) to Human Brain and Platelets: Potentiation by Tranylcypromine and Role of MAO Isoforms

J. Shih, M. I. Steinberg, R. T. Pickard, 1999, Annals of the New York Academy of Sciences.

Transcription factor binding to the core promoter of the human monoamine oxidase B gene in the cerebral cortex and in blood cells

J. Shih, L. Oreland, M. Damberg, 1998, Neuroscience Letters.

Increased stress response and beta-phenylethylamine in MAOB-deficient mice.

J. Shih, T. Kumazawa, J. Adams, 1997, Nature genetics.

Developmental expression pattern of monoamine oxidases in sensory organs and neural crest derivatives

P. Gaspar, C. Alvarez, T. Vitalis, 2003, The Journal of comparative neurology.

Autoantibody profiling of monoamine oxidase A knockout mice, an autism spectrum disorder model

J. Shih, F. R. Sutandy, Guan-Da Syu, 2022, Brain, Behavior, and Immunity.

De novo microdeletion of Xp11.3 exclusively encompassing the monoamine oxidase A and B genes in a male infant with episodic hypotonia: a genomics approach to personalized medicine.

J. Graham, J. Shih, Ryan E O'Leary, 2012, European journal of medical genetics.

A novel role for GAPDH-MAO B cascade in ethanol-induced cellular damage

H. Meltzer, A. Sawa, M. Austin, 2010 .

The VNTR 2 repeat in MAOA and delinquent behavior in adolescence and young adulthood: associations and MAOA promoter activity

X. Ou, J. Shih, G. Guo, 2008, European Journal of Human Genetics.

Cognitive abnormalities and hippocampal alterations in monoamine oxidase A and B knockout mice

Richard F. Thompson, J. Shih, Chanpreet Singh, 2013, Proceedings of the National Academy of Sciences of the United States of America.

Increased stress response and β–phenylethylamine in MAOB–deficient mice

Takeshi Kumazawa, M. Toth, J. Shih, 1997, Nature Genetics.

Development and Characterization of Monoclonal Antibodies Specific to the Serotonin 5-HT2A Receptor

Mark Ellisman, J. Shih, C. Wu, 1998, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Forebrain-specific Expression of Monoamine Oxidase A Reduces Neurotransmitter Levels, Restores the Brain Structure, and Rescues Aggressive Behavior in Monoamine Oxidase A-deficient Mice*

J. Shih, I. Rebrin, I. Seif, 2007, Journal of Biological Chemistry.

Monoamine oxidase A and A/B knockout mice display autistic-like features.

Ryan D. Darling, R. Lin, C. Wellman, 2013, The international journal of neuropsychopharmacology.

Substrate and Inhibitor Specificities for Human Monoamine Oxidase A and B Are Influenced by a Single Amino Acid*

J. Shih, I. Rebrin, J C Shih, 2001, The Journal of Biological Chemistry.

Transcriptional regulation and multiple functions of MAO genes

J. Shih, J. Wu, Kevin Chen, 2011, Journal of Neural Transmission.

Monoamine oxidase inactivation: from pathophysiology to therapeutics.

J. Shih, M. Bortolato, Marco Bortolato, 2008, Advanced drug delivery reviews.

MAOA-a novel decision maker of apoptosis and autophagy in hormone refractory neuroendocrine prostate cancer cells

C. Pan, J. Shih, Hsin-Chen Lee, 2017, Scientific Reports.

Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA.

P. Gaspar, J. Shih, C. Babinet, 1995, Science.

Molecular biology of serotonin (5-HT) receptors

J. Shih, T. Gallaher, Kevin Chen, 1991, Pharmacology Biochemistry and Behavior.

From aggression to autism: new perspectives on the behavioral sequelae of monoamine oxidase deficiency

J. Shih, M. Bortolato, Gabriele Floris, 2018, Journal of Neural Transmission.

Mutations in monoamine oxidase (MAO) genes in mice lead to hypersensitivity to serotonin-enhancing drugs: implications for drug side effects in humans

D. Murphy, J. Shih, M. Fox, 2012, The Pharmacogenomics Journal.

The Degradation of Serotonin: Role of MAO

J. Shih, M. Bortolato, Kevin Chen, 2010 .

Monoamine oxidase A knockout mice exhibit impaired nicotine preference but normal responses to novel stimuli.

N. Hiroi, J. Shih, I. Seif, 2006, Human molecular genetics.

Monoamine oxidase in neuropsychiatry and behavior.

J. Shih, R. Thompson, Jean C. Shih, 1999, American journal of human genetics.

PSYCHIATRIC GENETICS '99 Monoamine Oxidase in Neuropsychiatry and Behavior

J. Shih, R. Thompson, 1999 .

An Extensive Repeat Structure Down‐Regulates Human Monoamine Oxidase A Promoter Activity Independent of an Initiator‐Like Sequence

J. Shih, Q. Zhu, 1997, Journal of neurochemistry.

Gene-environment interactions in antisocial behavior are mediated by early-life 5-HT2A receptor activation

C. Wellman, S. Scheggi, C. Gambarana, 2019, Neuropharmacology.

Altered gene expression in early postnatal monoamine oxidase A knockout mice

B. Tabakoff, J. Shih, S. Flink, 2017, Brain Research.

Insights into enzyme point mutation effect by molecular simulation: phenylethylamine oxidation catalyzed by monoamine oxidase A.

Jernej Stare, Janez Mavri, Miha Purg, 2016, Physical chemistry chemical physics : PCCP.

Monoamine Oxidase A is Required for Rapid Dendritic Remodeling in Response to Stress

C. Wellman, J. Shih, M. Bortolato, 2015, The international journal of neuropsychopharmacology.

Early postnatal inhibition of serotonin synthesis results in long-term reductions of perseverative behaviors, but not aggression, in MAO A-deficient mice

M. Coba, J. Shih, M. Bortolato, 2013, Neuropharmacology.

Altered cerebellar organization and function in monoamine oxidase A hypomorphic mice

Ryan D. Darling, N. Volkow, P. Thanos, 2012, Neuropharmacology.

NMDARs Mediate the Role of Monoamine Oxidase A in Pathological Aggression

A. Urbani, R. Frau, J. Shih, 2012, The Journal of Neuroscience.

Maladaptive defensive behaviours in monoamine oxidase A-deficient mice.

R. Frau, J. Shih, M. Bortolato, 2011, The international journal of neuropsychopharmacology.

Altered Expression of Tyrosine Hydroxylase in the Locus Coeruleus Noradrenergic System in Citalopram Neonatally Exposed Rats and Monoamine Oxidase A Knock Out Mice

Ryan D. Darling, R. Lin, J. Shih, 2011, Anatomical record.

Social Deficits and Perseverative Behaviors, but not Overt Aggression, in MAO-A Hypomorphic Mice

C. Wellman, J. Shih, M. Bortolato, 2011, Neuropsychopharmacology.

Monoamine oxidase A regulates neural differentiation of murine embryonic stem cells

J. Shih, Qi-Long Ying, Ping Li, 2011, Journal of Neural Transmission.

Behavioral Disinhibition and Reduced Anxiety-like Behaviors in Monoamine Oxidase B-Deficient Mice

J. Shih, M. Bortolato, S. Godar, 2009, Neuropsychopharmacology.

Regulation of monoamine oxidase A by the SRY gene on the Y chromosome

Yun-Fai Chris Lau, J. Shih, J. Wu, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Monoamine oxidase A and repressor R1 are involved in apoptotic signaling pathway.

X. Ou, J. Shih, Kevin Chen, 2006, Proceedings of the National Academy of Sciences of the United States of America.

J. Shih, C. Teng, Zhiping Zhang, 2006, Molecular endocrinology.

A Spontaneous Point Mutation Produces Monoamine Oxidase A/B Knock-out Mice with Greatly Elevated Monoamines and Anxiety-like Behavior*♦

J. Shih, D. Holschneider, I. Rebrin, 2004, Journal of Biological Chemistry.

MAO‐B knockout mice exhibit deficient habituation of locomotor activity but normal nicotine intake

N. Hiroi, J. Shih, M. Lee, 2004, Genes, brain, and behavior.

Cloning, after cloning, knock-out mice, and physiological functions of MAO A and B.

J. Shih, 2004, Neurotoxicology.

Heart rate dynamics in monoamine oxidase-A- and -B-deficient mice.

D. Chialvo, O. Scremin, J. Shih, 2002, American journal of physiology. Heart and circulatory physiology.

Biochemical, behavioral, physiologic, and neurodevelopmental changes in mice deficient in monoamine oxidase A or B

J. Shih, D. Holschneider, I. Seif, 2001, Brain Research Bulletin.

Regional cerebral cortical activation in monoamine oxidase A-deficient mice: differential effects of chronic versus acute elevations in serotonin and norepinephrine

O. Scremin, J. Shih, D. Holschneider, 2000, Neuroscience.

Phe208 and Ile199 in Human Monoamine Oxidase A and B Do Not Determine Substrate and Inhibitor Specificities as in Rat

J. Shih, Kevin Chen, R. M. Geha, 2000, Journal of neurochemistry.

Selective enhancement of emotional, but not motor, learning in monoamine oxidase A-deficient mice.

M. Fanselow, L. Chen, J. J. Kim, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Localization of monoamine oxidase A and B mRNA in the rat brain by in situ hybridization

T. Joh, J. Shih, J. Jahng, 1997, Synapse.

Bidirectional promoter of human monoamine oxidase A (MAO A) controlled by transcription factor Sp1

J. Shih, Q. Zhu, K. Chen, 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Valproic Acid Induces Monoamine Oxidase A via Akt/FoxO1 Activation

J. Shih, J. Wu, 2011 .

Possible interaction between MAOA and DRD2 genes associated with antisocial alcoholism among Han Chinese men in Taiwan

H. Ko, J. Shih, R. Lu, 2007, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Glucocorticoid and Androgen Activation of Monoamine Oxidase A Is Regulated Differently by R1 and Sp1*

X. Ou, J. Shih, Kevin Chen, 2006, Journal of Biological Chemistry.

Contributions of the DAT1 and DRD2 genes to serious and violent delinquency among adolescents and young adults

J. Shih, G. Guo, M. Roettger, 2007, Human Genetics.

Monoamine oxidase A (MAO A) inhibitors decrease glioma progression

Thomas C Chen, S. Groshen, J. Shih, 2016, Oncotarget.

Yang-Gan-Wan protects mice against experimental liver damage.

J. Shih, M. Yang, K. Chen, 2000, The American journal of Chinese medicine.

A transient placental source of serotonin for the fetal forebrain

E. Deneris, R. Blakely, P. Levitt, 2011, Nature.

Monoamine oxidase A inhibitor-near-infrared dye conjugate reduces prostate tumor growth.

J. Shih, B. Olenyuk, H. Zhau, 2015, Journal of the American Chemical Society.

Expression of Functional Human Monoamine Oxidase A and B cDNAs in Mammalian Cells

J. Shih, N. Lan, J. Shih, 1989, Journal of neurochemistry.

Regulation of MAO-A and MAO-B gene expression.

J. Shih, Kevin Chen, K. Chen, 2004, Current medicinal chemistry.

Dopamine metabolism by a monoamine oxidase mitochondrial shuttle activates the electron transport chain

Steven M. Graves, P. Greengard, D. Surmeier, 2019, Nature Neuroscience.

Effect of Monoamine oxidase A (MAOA) inhibitors on androgen‐sensitive and castration‐resistant prostate cancer cells

Chun-Peng Liao, M. Gross, S. Gaur, 2019, The Prostate.

Phase 2 trial of monoamine oxidase inhibitor phenelzine in biochemical recurrent prostate cancer

J. Pinski, M. Gross, T. Dorff, 2020, Prostate Cancer and Prostatic Diseases.

Phase 2 Trial of Monoamine Oxidase Inhibitor Phenelzine in Biochemical Recurrent Prostate Cancer

J. Pinski, M. Gross, T. Dorff, 2020, Prostate Cancer and Prostatic Diseases.

Increased baroreceptor response in mice deficient in monoamine oxidase A and B.

D. Chialvo, O. Scremin, J. Shih, 2002, American journal of physiology. Heart and circulatory physiology.

Promoter organization and activity of human monoamine oxidase (MAO) A and B genes

J. Shih, J. Grimsby, Q. Zhu, 1992, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Identification of 5‐Hydroxytryptamine1A Receptor Proteins in Bovine Frontal Cortex

J. Shih, Y. Takeuchi, Wu Yang, 1988, Journal of neurochemistry.

Photoaffinity Labeling of the 5‐HydroxytryptamineIA Receptor in Rat Hippocampus

J. Shih, R. Ransom, J. Shih, 1986, Journal of neurochemistry.

[3H]1‐[2‐(4‐Aminophenyl)Ethyl]‐4‐(3‐Trifluoromethylphenyl)Piperazine: A Selective Radioligand for 5‐HT1A Receptors in Rat Brain

J. Shih, R. Ransom, K. Asarch, 1986, Journal of neurochemistry.

A Trifluoromethylphenyl Piperazine Derivative with High Affinity for 5‐Hydroxytryptamine‐1A Sites in Rat Brain

J. Shih, R. Ransom, K. Asarch, 1985, Journal of neurochemistry.

Systematic screening for mutations in the human serotonin-2A (5-HT2A) receptor gene: Identification of two naturally occurring receptor variants and association analysis in schizophrenia

M. Rietschel, M. Nöthen, W. Maier, 1996, Human Genetics.

Inhibition of Monoamine Oxidase by Phenyl Azides

J. Shih, Shiuan Chen, S. Chen, 1985, Journal of neurochemistry.

Schizophrenia, Monoamine Oxidase Activity, and Cigarette Smoking

G. Simpson, J. Shih, Kevin Chen, 1999, Neuropsychopharmacology.

Breast cancer and neurotransmitters: emerging insights on mechanisms and therapeutic directions

H. Lenz, J. Millstein, D. Spicer, 2023, Oncogene.

Gene structure and expression of the mouse 5‐HT2 receptor

J. Shih, N. Lan, T. Gallaher, 1992, Journal of neuroscience research.

The human 5-HT2 receptor is encoded by a multiple intron-exon gene.

J. Shih, J. Grimsby, W. Yang, 1992, Brain research. Molecular brain research.

Structure and promoter organization of the human monoamine oxidase A and B genes.

J. Shih, J. Grimsby, Q. Zhu, 1993, Journal of psychiatry & neuroscience : JPN.

Characterization of the human 5-HT2A receptor gene promoter

J. Shih, Q. Zhu, Kevin Chen, 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Determination of transcription initiation sites and promoter activity of the human 5-HT2A receptor gene

J. Shih, Q. Zhu, Kevin Chen, 1995, Behavioural Brain Research.

Prenatal Exposure to Urban Air Nanoparticles in Mice Causes Altered Neuronal Differentiation and Depression-Like Responses

K. Berhane, T. Morgan, C. Finch, 2013, PloS one.

Near-Infrared MAO A Inhibitor (NMI) Outperformed FDA-Approved Chemotherapeutic Agents in Brain and Other Cancers: A Bioinformatic Analysis of NCI60 Screening Data

J. Shih, Qianhua Feng, Yihan Qian, 2021, Brain sciences.

Monoamine oxidase A and organic cation transporter 3 coordinate intracellular β1AR signaling to calibrate cardiac contractile function

J. Hell, J. Shih, N. Kaludercic, 2022, Basic Research in Cardiology.

Loss of MAOA in epithelia inhibits adenocarcinoma development, cell proliferation and cancer stem cells in prostate

Chun-Peng Liao, M. Gross, Chi-Hung Lin, 2018, Oncogene.

PAMs inhibits monoamine oxidase a activity and reduces glioma tumor growth, a potential adjuvant treatment for glioma

Chieh-Hsi Wu, J. Shih, C. Mao, 2020, BMC Complementary Medicine and Therapies.

Dual Functions of Transcription Factors, Transforming Growth Factor-β-inducible Early Gene (TIEG)2 and Sp3, Are Mediated by CACCC Element and Sp1 Sites of Human Monoamine Oxidase (MAO) B Gene*

X. Ou, J. Shih, Kevin Chen, 2004, Journal of Biological Chemistry.

Determination of regions important for monoamine oxidase (MAO) A and B substrate and inhibitor selectivities.

J. Shih, R. M. Geha, K. Chen, 1998, Journal of neural transmission. Supplementum.

Quantification and pharmacokinetic study of tumor-targeting agent MHI148-clorgyline amide in mouse plasma using liquid chromatography-electrospray ionization tandem mass spectrometry

J. Shih, B. Olenyuk, Zhijun Wang, 2017, Journal of pharmaceutical analysis.

Near-Infrared Monoamine Oxidase Inhibitor Biodistribution in a Glioma Mouse Model

J. Shih, R. Irwin, A. R. Escobedo, 2021, Pharmaceutical Research.

Down-Regulated GABAergic Expression in the Olfactory Bulb Layers of the Mouse Deficient in Monoamine Oxidase B and Administered With Amphetamine

J. Shih, H. Yin, T. Tien, 2010, Cellular and Molecular Neurobiology.

Differential effects of chronic amphetamine and baclofen administration on cAMP levels and phosphorylation of CREB in distinct brain regions of wild type and monoamine oxidase B‐deficient mice

J. Shih, S. Kalpana, H. Yin, 2006, Synapse.

Analysis of Conserved Active Site Residues in Monoamine Oxidase A and B and Their Three-dimensional Molecular Modeling*

J. Wouters, J. Shih, F. Ooms, 2002, The Journal of Biological Chemistry.

Influence of C Terminus on Monoamine Oxidase A and B Catalytic Activity

J. Shih, Kevin Chen, Hsiu‐Fei Wu, 1996, Journal of Neurochemistry.

Lack of protection of monoamine oxidase B-deficient mice from age-related spatial learning deficits in the Morris water maze.

O. Scremin, J. Shih, D. Holschneider, 1999, Life sciences.

Dinucleotide repeat (TG)23 polymorphism in the MAOB gene.

C. R. Cloninger, E. Devor, J. Shih, 1992, Nucleic acids research.

Design, synthesis, and biological activity of dual monoamine oxidase A and heat shock protein 90 inhibitors, N-Methylpropargylamine-conjugated 4-isopropylresorcinol for glioblastoma.

J. Shih, J. Liou, Kuo-Hsiang Chuang, 2023, European journal of medicinal chemistry.

MAO-A and -B gene knock-out mice exhibit distinctly different behavior.

J. Shih, J C Shih, K Chen, 1999, Neurobiology.

The expression of human MAO-A and B genes.

J. Shih, J. Grimsby, K. Chen, 1990, Journal of neural transmission. Supplementum.

Hyperserotoninemia and antiserotonin antibodies in autism and other disorders

B. King, G. Hanna, E. Ritvo, 1992, Journal of autism and developmental disorders.

Abnormal stress response and increased fighting behavior in mice lacking the bcr gene product.

J. Voncken, N. Heisterkamp, J. Groffen, 1998, International journal of molecular medicine.

Modulation of [3H]quinpirole binding at striatal D2 dopamine receptors by a monoamine oxidaseA-like site: evidence from radioligand binding studies and D2 receptor- and MAO(A)-deficient mice.

D. Grandy, J. Shih, I. Seif, 2001, Life sciences.

R1 Regulates Prostate Tumor Growth and Progression By Transcriptional Suppression of the E3 Ligase HUWE1 to Stabilize c-Myc

Chi-Hung Lin, J. Shih, H. Zhau, 2018, Molecular Cancer Research.

Insights into enzyme point mutation effect by molecular simulation: phenylethylamine oxidation catalyzed by monoamine oxidase A.

J. Shih, J. Mavri, Miha Purg, 2016, Physical chemistry chemical physics : PCCP.

Regulation of human monoamine oxidase B gene by Sp1 and Sp3.

J. Shih, Kevin Chen, Wai K. Wong, 2001, Molecular pharmacology.

Maladaptive defensive behaviours in monoamine oxidase A-deficient mice.

R. Frau, J. Shih, M. Bortolato, 2011, The international journal of neuropsychopharmacology.

Altered gene expression in early postnatal monoamine oxidase A knockout mice

B. Tabakoff, J. Shih, S. Flink, 2017, Brain Research.

N-Methylpropargylamine-Conjugated Hydroxamic Acids as Dual Inhibitors of Monoamine Oxidase A and Histone Deacetylase for Glioma Treatment.

J. Shih, Samir Mehndiratta, J. Liou, 2022, Journal of medicinal chemistry.

Molecular basis of human MAO A and B.

J. Shih, 1991, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.