P. Nambi

发表

Adrenomedullin decreases extracellular signal-regulated kinase activity through an increase in protein phosphatase-2A activity in mesangial cells.

D. Brooks, N. Parameswaran, P. Nambi, 2000, European journal of pharmacology.

Activation of multiple mitogen-activated protein kinases by recombinant calcitonin gene-related peptide receptor.

N. Aiyar, D. Brooks, N. Parameswaran, 2000, European journal of pharmacology.

Regulation of glomerular mesangial cell proliferation in culture by adrenomedullin.

D. Brooks, N. Parameswaran, P. Nambi, 1999, European journal of pharmacology.

Upregulation of osteopontin in ischemia-induced renal failure in rats: a role for ET-1?

H. Wu, P. Nambi, U. Prabhakar, 1997, Biochemical and biophysical research communications.

Gene-selective modulation by a synthetic oxysterol ligand of the liver X receptor Published, JLR Papers in Press, August 1, 2004. DOI 10.1194/jlr.M400257-JLR200

Liang Chen, P. Nambi, Ponnal Nambi, 2004, Journal of Lipid Research.

Quinoline-3-carboxamide containing sulfones as liver X receptor (LXR) agonists with binding selectivity for LXRbeta and low blood-brain penetration.

Anna Wilhelmsson, P. Nambi, M. Evans, 2010, Bioorganic & medicinal chemistry letters.

Adipocyte fatty acid-binding protein (aP2), a newly identified LXR target gene, is induced by LXR agonists in human THP-1 cells

P. Nambi, Qiangyuan Liu, E. Quinet, 2007, Molecular and Cellular Biochemistry.

Indazole-based liver X receptor (LXR) modulators with maintained atherosclerotic lesion reduction activity but diminished stimulation of hepatic triglyceride synthesis.

Robert Steffan, Anna Wilhelmsson, T. Bonn, 2008, Journal of medicinal chemistry.

LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse[S]

P. Nambi, M. Evans, Wenyan Zhong, 2009, Journal of Lipid Research.

Renal vasopressin receptor expression and function in rats following spaceflight.

C. Wade, D. Brooks, B. Olson, 2000, Journal of applied physiology.

Mechanism of adrenomedullin-stimulated hyaluronic acid release in rat mesangial cells.

D. Brooks, N. Parameswaran, P. Nambi, 1999, European journal of pharmacology.

SB203580 reverses adrenomedullin's effect on proliferation and apoptosis in cultured mesangial cells.

D. Brooks, N. Parameswaran, P. Nambi, 1999, European journal of pharmacology.

Desensitization and resensitization of adrenomedullin-sensitive receptor in rat mesangial cells.

N. Aiyar, H. Wu, D. Brooks, 2000, European journal of pharmacology.

Receptor activity modifying proteins interaction with human and porcine calcitonin receptor-like receptor (CRLR) in HEK-293 cells

N. Aiyar, P. Nambi, J. Disa, 2001, Molecular and Cellular Biochemistry.

Determination of the molecular size of frog and turkey erythrocyte .beta.-adrenergic receptors by radiation inactivation

M. Caron, R. Lefkowitz, P. Nambi, 1984 .

Endothelin and Heart Failure

G. Feuerstein, P. Nambi, M. Clozel, 2001, Heart Failure Reviews.

Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells

A. Dorner, P. Nambi, M. Evans, 2008, Journal of Translational Medicine.

Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase. Structural alterations in the beta-adrenergic receptor revealed by photoaffinity labeling.

M. Caron, R. Lefkowitz, P. Nambi, 1982, The Journal of biological chemistry.

Endothelin stimulates 86Rb efflux in rat glioma C6-Bu-1 cells

N. Aiyar, P. Nambi, M. Gleason, 1991, Neuropeptides.

Oxytocin induces a transient increase in cytosolic free [Ca2+] in renal tubular epithelial cells: evidence for oxytocin receptors on LLC-PK1 cells.

H. Sarau, N. Aiyar, P. Nambi, 1988, Molecular pharmacology.

Endothelin and the kidney

P. Nambi, 2000 .

Activation of glomerular mesangial cells by hepatocyte growth factor through tyrosine kinase and protein kinase C.

B. Olson, N. Laping, P. Nambi, 1998, Biochemical pharmacology.

Desensitization of the beta-adrenergic receptor of frog erythrocytes. Recovery and characterization of the down-regulated receptors in sequestered vesicles.

B. Strulovici, M. Caron, R. Lefkowitz, 1983, The Journal of biological chemistry.

Endothelin and platelet function.

E. Ohlstein, P. Nambi, M. Given, 1990, Thrombosis research.

Transforming Growth Factor-β-Mediated Proliferation of Renal Tubular Epithelial Cells Involves Pertussis Toxin-Sensitive G Protein- and Protein Kinase C-Dependent Pathways

P. Nambi, Hsiao-ling Wu, 1998, Pharmacology.

Biochemical characterization of phosphorylated beta-adrenergic receptors from catecholamine-desensitized turkey erythrocytes.

S. Crooke, P. Nambi, J. Stadel, 1986, Biochemistry.

GW3965, a synthetic liver X receptor (LXR) agonist, reduces angiotensin II‐mediated pressor responses in Sprague–Dawley rats

P. Nambi, Q.-Y. Liu, J. Hennan, 2007, British journal of pharmacology.

5-(5,6-Dichloro-2-indolyl)-2-methoxy-2,4-pentadienamides: novel and selective inhibitors of the vacuolar H+-ATPase of osteoclasts with bone antiresorptive activity.

P. Nambi, C. Parini, S. Gagliardi, 1998, Journal of medicinal chemistry.

Sex difference in the antidiuretic activity of vasopressin in the rat.

D. Brooks, P. Nambi, L. Share, 1993, The American journal of physiology.

Identification and characterization of a novel endothelin receptor that binds both ETA- and ETB-selective ligands.

N. Aiyar, D. Brooks, P. Nambi, 1997, Molecular pharmacology.

Contribution of endogenous endothelin-1 to the maintenance of vascular tone: role of nitric oxide.

P. Nambi, M. Gellai, T. Fletcher, 1997, Pharmacology.

Nonpeptide endothelin receptor antagonists. II. Pharmacological characterization of SB 209670.

J. D. Elliott, S. Douglas, R. Ruffolo, 1994, The Journal of pharmacology and experimental therapeutics.

Effect of thrombin on proliferation, contraction and prostaglandin production of rat glomerular mesangial cells in culture.

P. Nambi, T. Groom, G. Dytko, 1992, The Journal of pharmacology and experimental therapeutics.

Distribution and functional role of renal ET receptor subtypes in normotensive and hypertensive rats.

P. Nambi, M. Gellai, M. Pullen, 1994, Kidney international.

Sirolimus upregulates aP2 expression in human monocytes and macrophages.

P. Nambi, Q.-Y. Liu, 2004, Transplantation proceedings.

125I-labeled p-azidobenzylcarazolol, a photoaffinity label for the beta-adrenergic receptor. Characterization of the ligand and photoaffinity labeling of beta 1- and beta 2-adrenergic receptors.

M. Caron, R. Lefkowitz, P. Nambi, 1982, The Journal of biological chemistry.

Endothelin receptor subtype distribution predisposes coronary arteries to damage.

L. Tierney, P. Nambi, C. Louden, 2000, The American journal of pathology.

Coronary arterial lesions in dogs treated with an endothelin receptor antagonist.

P. Nambi, C. Louden, H. Solleveld, 1998, Journal of cardiovascular pharmacology.

Abstract 1453: LXR-623, a novel Liver X Receptor modulator, displays neutral lipid effects in Cholesteryl Ester Transfer Protein-expressing species and inhibits atherosclerotic lesion progression in Low Density Lipoprotein receptor knockout mice

P. Nambi, J. Keith, R. Steffan, 2007 .

Regulation of topoisomerase I and II activities by cyclic nucleotide- and phospholipid-dependent protein kinases. Effects of interactions between the two transduction pathways.

S. Crooke, P. Nambi, J. Bartus, 1991, Receptor.

11 - Endothelin Receptors in Neural Systems

P. Nambi, P. Lysko, P. G. Lysko, 1993 .

Expression of human preproendothelin-1 cDNA in COS cells results in the production of mature vasoactive endothelin-1.

A. Dilella, N. Elshourbagy, E. Ohlstein, 1991, Biochemical and biophysical research communications.

Identification of endothelin receptors in various regions of rat brain

G. Feuerstein, P. Nambi, M. Pullen, 1990, Neuropeptides.

Nonpeptide endothelin receptor antagonists. VII: Binding characteristics of [3H]SB 209670, a novel nonpeptide antagonist of endothelin receptors.

N. Aiyar, H. Wu, R. Ruffolo, 1996, Journal of Pharmacology and Experimental Therapeutics.

Distribution of Neutral Endopeptidase Activity along the Rat and Rabbit Nephron

P. Nambi, R. Edwards, M. Pullen, 1999, Pharmacology.

Absence of endothelin receptors and receptor mRNA in mammalian fibroblasts transformed with SV40 or ras oncogene

G. Hofmann, P. Nambi, M. Mattern, 1997, Molecular and Cellular Biochemistry.

Binding characteristics of [125I]TTA 386, ETA-selective antagonist

P. Nambi, G. Brown, M. Pullen, 1997, Neuropeptides.

Correlation between guanine nucleotide effect and reversible binding property of endothelin analogs

N. Aiyar, P. Nambi, M. Pullen, 1996, Neuropeptides.

Identification of ETB receptor subtypes using linear and truncated analogs of ET

D. Brooks, P. Nambi, M. Gellai, 1995, Neuropeptides.

[125I]-BQ3020, a potent ETB-selective agonist, displays species differences in its binding characteristics

P. Nambi, M. Pullen, 1995, Neuropeptides.

Identification of a novel endothelin receptor in Xenopus laevis liver

P. Nambi, M. Pullen, C. Kumar, 1994, Neuropeptides.

Identification and characterization of triosephosphate isomerase that specifically interacts with the integrin αIIb cytoplasmic domain

G. Feuerstein, P. Nambi, Qiangyuan Liu, 2006 .

Molecular cloning and pharmacological characterization of bovine calcitonin receptor-like receptor from bovine aortic endothelial cells.

N. Aiyar, Z. Ao, S. Douglas, 2002, Biochemical pharmacology.

Homologous desensitization of calcitonin gene-related peptide response in rat glomerular mesangial cells in culture

N. Aiyar, G. Feuerstein, P. Nambi, 1992, Molecular and Cellular Biochemistry.

Differential effects of guanine nucleotides on [125I]-hCGRP(8–37) binding to porcine lung and human neuroblastoma cell membranes

N. Aiyar, P. Nambi, J. Disa, 1997, Neuropeptides.

Identification and characterization of calcitonin gene-related peptide receptors in porcine renal medullary membranes.

N. Aiyar, G. Feuerstein, P. Nambi, 1991, Endocrinology.

Dexamethasone down-regulates the expression of endothelin receptors in vascular smooth muscle cells.

H. Wu, N. Elshourbagy, P. Nambi, 1992, The Journal of biological chemistry.

Measurement of responses from Gi-, Gs-, or Gq-coupled receptors by a multiple response element/cAMP response element-directed reporter assay.

L. Fitzgerald, H. Wu, P. Nambi, 1999, Analytical biochemistry.

Protein kinase C regulates TNF-alpha production by human monocytes.

S. Kassis, P. Nambi, U. Prabhakar, 1993, European cytokine network.

Photoaffinity labeling of β-adrenergic receptors in mammalian tissues

D. Sibley, M. Caron, R. Lefkowitz, 1984 .

Species differences in the binding characteristics of [125I]IRL-1620, a potent agonist specific for endothelin-B receptors.

P. Nambi, W. Spielman, M. Pullen, 1994, The Journal of pharmacology and experimental therapeutics.

Reversal of postischemic acute renal failure with a selective endothelinA receptor antagonist in the rat.

P. Nambi, M. Gellai, R. DeWolf, 1994, The Journal of clinical investigation.

SYMPOSIUM Experimental Biology 1995 Endothelin Receptors: Role in Renal Function and Dysfunction ENDOTHELIN RECEPTORS IN NORMAL AND DISEASED KIDNEYS

P. Nambi, 1996 .

Endothelin receptors in normal and diseased kidneys.

P. Nambi, 1996, Clinical and experimental pharmacology & physiology.

Okadaic acid stimulates caspase-like activities and induces apoptosis of cultured rat mesangial cells

D. Brooks, N. Parameswaran, P. Nambi, 2004, Molecular and Cellular Biochemistry.

Effect of nifedipine on cyclosporine A-induced nephrotoxicity, urinary endothelin excretion and renal endothelin receptor number.

D. Brooks, E. Ohlstein, P. Nambi, 1991, European journal of pharmacology.

Relationship of calcium and membrane guanylate cyclase in adrenocorticotropin-induced steroidogenesis.

N. Aiyar, R. Sharma, P. Nambi, 1982, Endocrinology.

Liver X receptor (LXR)-beta regulation in LXRalpha-deficient mice: implications for therapeutic targeting.

J. Gustafsson, Liang Chen, P. Nambi, 2006, Molecular pharmacology.

Evidence for involvement of protein kinase C in expression of intracellular adhesion molecule-1 (ICAM-1) by human vascular endothelial cells.

P. Nambi, C. Sung, A. Arleth, 1994, Pharmacology.

Characterization of a functional angiotensin II receptor in Xenopus laevis heart.

N. Aiyar, D. Bergsma, P. Nambi, 1994, Pharmacology.

Down regulation of kidney neutral endopeptidase mRNA, protein and activity during acute renal failure: Possible mechanism for ischemia-induced acute renal failure in rats?

L. Hersh, P. Nambi, U. Prabhakar, 1999, Molecular and Cellular Biochemistry.

A novel series of ETA selective antagonists

J. D. Elliott, E. Ohlstein, P. Nambi, 2002 .

An efficient approach to the synthesis of 1,3-diaryl-1,2,3,4-[4H]-tetrahydronaphthalene-2-carboxylic acids.

J. D. Elliott, E. Ohlstein, P. Nambi, 1998, Bioorganic & medicinal chemistry.

Novel Endothelin Receptors

P. Nambi, 1998 .

SB 209670, a rationally designed potent nonpeptide endothelin receptor antagonist.

S. Douglas, E. Ohlstein, P. Nambi, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Identification of endothelin receptor subtypes in human renal cortex and medulla using subtype-selective ligands.

N. Aiyar, H. Wu, E. Ohlstein, 1992, Endocrinology.

Comparison of endothelin binding and calcium mobilization in C6-BU-1 rat glioma and N18TG2 mouse neuroblastoma cells

H. Wu, T. Yue, G. Feuerstein, 1991, Neuropeptides.

Identification of endothelin receptors in cultured cerebellar neurons

H. Wu, G. Feuerstein, P. Nambi, 1991, Neuropeptides.

Inhibition of endothelin‐mediated topoisomerase I activation by pertussis toxin

H. Wu, P. Nambi, M. Mattern, 1990, FEBS letters.

Upregulation of renal endothelin receptors in rats with cyclosporine A-induced nephrotoxicity.

D. Brooks, P. Nambi, M. Pullen, 1990, European journal of pharmacology.

Catecholamine and guanine nucleotide activation of skeletal muscle adenylate cyclase.

P. Nambi, G. Drummond, 1979, Biochimica et biophysica acta.

Induction of c‐fos protein by activation of vasopressin receptors in smooth muscle cells

J. Moore, G. Evan, N. Aiyar, 1989, FEBS letters.

Epithelin mRNA expression in polycystic kidney disease

D. Brooks, P. Nambi, T. Fredrickson, 1999, Peptides.

Nonpeptide endothelin receptor antagonists. V: Prevention and reversal of acute renal failure in the rat by SB 209670.

J. D. Elliott, D. Brooks, E. Ohlstein, 1995, The Journal of pharmacology and experimental therapeutics.

Vasopressin-mediated inhibition of atrial natriuretic factor-stimulated cGMP accumulation in an established smooth muscle cell line.

N. Aiyar, S. Crooke, P. Nambi, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Vascular vasopressin receptors mediate phosphatidylinositol turnover and calcium efflux in an established smooth muscle cell line.

N. Aiyar, S. Crooke, P. Nambi, 1986, Life sciences.

Phorbol diester treatment promotes enhanced adenylate cyclase activity in frog erythrocytes.

D. Sibley, R. Lefkowitz, P. Nambi, 1986, Archives of biochemistry and biophysics.

Pharmacologic characterization of the novel, orally available endothelin-A--selective antagonist SB 247083.

J. D. Elliott, J. Luengo, S. Douglas, 1998, Journal of cardiovascular pharmacology.

Adenylate Cyclase in Heart and Skeletal Muscle

M. Sano, P. Nambi, G. Drummond, 1979 .

Increase in renal phorbol ester receptors in rats with cyclosporine A-induced nephrotoxicity.

H. Wu, D. Brooks, P. Nambi, 1991, European journal of pharmacology.

Vasopressin V1 receptors and inter-receptor regulation in vascular smooth muscle cells.

N. Aiyar, S. Crooke, P. Nambi, 1988, Biochemical pharmacology.

Endothelin inhibits vasopressin action in rat inner medullary collecting duct via the ETB receptor.

P. Nambi, R. Edwards, M. Pullen, 1993, The Journal of pharmacology and experimental therapeutics.

Involvement of G protein-coupled receptor kinase-6 in desensitization of CGRP receptors.

N. Aiyar, J. Benovic, P. Nambi, 2000, European journal of pharmacology.

Effect of pharmacologic plasminogen activator inhibitor‐1 inhibition on cell motility and tumor angiogenesis

D. Lawrence, P. Nambi, C. E. Leik, 2006, Journal of thrombosis and haemostasis : JTH.

Enhanced adenylate cyclase activity of turkey erythrocytes following treatment with beta-adrenergic receptor antagonists.

D. Sibley, R. Lefkowitz, P. Nambi, 1984, European Journal of Pharmacology.

Stimulation of Hyaluronan Synthetase by Platelet-Derived Growth Factor bb in Human Prostate Smooth Muscle Cells

P. Nambi, K. Thomas, M. Pullen, 2001, Pharmacology.

Vascular vasopressin receptors mediate inhibition of beta adrenergic receptor-induced cyclic AMP accumulation.

S. Crooke, P. Nambi, F. Stassen, 1986, The Journal of pharmacology and experimental therapeutics.

Characterization of canine renal endothelin receptor subtypes and their function.

D. Brooks, P. Nambi, M. Pullen, 1994, The Journal of pharmacology and experimental therapeutics.

Cell-free desensitization of catecholamine-sensitive adenylate cyclase. Agonist- and cAMP-promoted alterations in turkey erythrocyte beta-adrenergic receptors.

D. Sibley, R. Lefkowitz, P. Nambi, 1984, Journal of Biological Chemistry.

Cell-free Desensitization of Catecholamine-sensitive Adenylate

D. Sibley, R. Lefkowitz, P. Nambi, 1984 .

Further modification on phenyl acetic acid based quinolines as liver X receptor modulators.

Farooq Azam, Anna Wilhelmsson, James Jetter, 2007, Bioorganic & medicinal chemistry.

Discovery of phenyl acetic acid substituted quinolines as novel liver X receptor agonists for the treatment of atherosclerosis.

Christopher Miller, Farooq Azam, Anna Wilhelmsson, 2006, Journal of medicinal chemistry.

Discovery and SAR of cinnolines/quinolines as liver X receptor (LXR) agonists with binding selectivity for LXRbeta.

P. Nambi, Baihua Hu, Raymound Unwalla, 2009, Bioorganic & medicinal chemistry.

Biarylether amide quinolines as liver X receptor agonists.

Anna Wilhelmsson, John Ullrich, P. Nambi, 2009, Bioorganic & medicinal chemistry.

3-(3-Aryloxyaryl)imidazo[1,2-a]pyridine sulfones as liver X receptor agonists.

Robert Steffan, Anna Wilhelmsson, P. Nambi, 2010, Bioorganic & medicinal chemistry letters.

1,3-Diarylindan-2-carboxylic acids, potent and selective non-peptide endothelin receptor antagonists.

J. D. Elliott, N. Elshourbagy, K. Erhard, 1994, Journal of medicinal chemistry.

Phorbol ester-mediated inhibition of vasopressin and beta-adrenergic responses in a vascular smooth muscle cell line.

N. Aiyar, S. Crooke, P. Nambi, 1987, Molecular pharmacology.

Thrombin-mediated down-regulation of endothelin receptors in mesangial cells coincides with the down-regulation of neutral endopeptidase activity.

L. Hersh, H. Wu, P. Nambi, 1995, Molecular Pharmacology.

Selective inhibition of rat mesangial cell proliferation by a synthetic peptide derived from the sequence of the C2 region of PKCβ

P. Nambi, C. Albrightson, Hsiao-ling Wu, 1999, Peptides.

Solubilization of epinephrine‐specific α2‐adrenergic receptors from adrenocortical carcinoma

N. Aiyar, R. Sharma, P. Nambi, 1982, FEBS letters.

Adrenocorticotropin-dependent particulate guanylate cyclase in rat adrenal and adrenocortical carcinoma: comparison of its properties with soluble guanylate cyclase and its relationship with ACTH-induced steroidogenesis.

N. Aiyar, R. Sharma, P. Nambi, 1982, Archives of biochemistry and biophysics.

Adrenocorticotropic hormone-responsive guanylate cyclase in the particulate fraction of rat adrenal glands.

R. Sharma, P. Nambi, 1981, Endocrinology.

Phorbol diesters promote beta-adrenergic receptor phosphorylation and adenylate cyclase desensitization in duck erythrocytes.

D. Sibley, R. Lefkowitz, P. Nambi, 1984, Biochemical and biophysical research communications.

Human AT1 receptor is a single copy gene: Characterization in a stable cell line

J. Trill, N. Aiyar, D. Bergsma, 1994, Molecular and Cellular Biochemistry.

Nonpeptide endothelin receptor antagonists. I. Effects on binding and signal transduction on human endothelinA and endothelinB receptors.

J. D. Elliott, H. Wu, N. Elshourbagy, 1994, The Journal of pharmacology and experimental therapeutics.

Demonstration of ACTH-sensitive particulate guanylate cyclase in adrenocortical carcinoma.

R. Sharma, P. Nambi, 1981, Biochemical and biophysical research communications.

Nonpeptide endothelin receptor antagonists. III. Effect of SB 209670 and BQ123 on acute renal failure in anesthetized dogs.

J. D. Elliott, R. Ruffolo, D. Brooks, 1994, The Journal of pharmacology and experimental therapeutics.

Identification and characterization of vascular (V1) vasopressin receptors of an established smooth muscle cell line.

N. Aiyar, S. Crooke, P. Nambi, 1987, Molecular Pharmacology.

Novel endothelin receptors in the follicular membranes of Xenopus laevis oocytes mediate calcium responses by signal transduction through gap junctions.

P. Nambi, P. Nuthulaganti, M. Pullen, 1993, Molecular pharmacology.

Phosphorylation of the beta-adrenergic receptor accompanies catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase.

M. Caron, R. Lefkowitz, P. Nambi, 1983, Transactions of the Association of American Physicians.

Skeletal muscle adenylate cyclase: reconstitution of fluoride and guanylnucleotide sensitivity.

M. Sano, P. Nambi, G. Drummond, 1980, Archives of biochemistry and biophysics.

Identification and characterization of triosephosphate isomerase that specifically interacts with the integrin alphaIIb cytoplasmic domain.

G. Feuerstein, P. Nambi, Qiangyuan Liu, 2006, Biochemical pharmacology.

Isolation and expression of a novel angiotensin II receptor from Xenopus laevis heart.

N. Aiyar, D. Bergsma, C. Ellis, 1993, Molecular pharmacology.

P. Nambi, U. Prabhakar, 1999 .

Nonpeptide endothelin receptor antagonists. XI. Pharmacological characterization of SB 234551, a high-affinity and selective nonpeptide ETA receptor antagonist.

J. D. Elliott, J. Luengo, D. Brooks, 1998, The Journal of pharmacology and experimental therapeutics.

SB 234551, a novel endothelin--A receptor antagonist, unmasks endothelin-induced renal vasodilatation in the dog.

J. D. Elliott, D. Brooks, E. Ohlstein, 1998, Journal of cardiovascular pharmacology.

Evidence for the existence of endothelin-B receptor subtypes and their physiological roles in the rat.

P. Nambi, M. Gellai, M. Pullen, 1996, The American journal of physiology.

Stimulation of intracellular topoisomerase I activity by vasopressin and thrombin. Differential regulation by pertussis toxin.

N. Aiyar, S. Crooke, P. Nambi, 1989, The Biochemical journal.

Liver X Receptor (LXR)-β Regulation in LXRα-Deficient Mice: Implications for Therapeutic Targeting

J. Gustafsson, Liang Chen, P. Nambi, 2006, Molecular Pharmacology.

1-(3-Aryloxyaryl)benzimidazole sulfones are liver X receptor agonists.

Anna Wilhelmsson, P. Nambi, R. Bernotas, 2010, Bioorganic & medicinal chemistry letters.

G protein-coupled receptors in drug discovery.

N. Aiyar, P. Nambi, Nambi Aiyar, 2003, Assay and drug development technologies.

Activation of endothelin ETB receptors increases glomerular cGMP via an L-arginine-dependent pathway.

P. Nambi, R. Edwards, M. Pullen, 1992, The American journal of physiology.

Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptor.

M. Caron, R. Lefkowitz, P. Nambi, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Molecular Characterization of a Novel Human Endothelin Receptor Splice Variant*

N. Elshourbagy, P. Nambi, J. Adamou, 1996, The Journal of Biological Chemistry.

Effects of endothelin receptor antagonism and angiotensin-converting enzyme inhibition on cardiac and renal remodeling in the rat.

R. Willette, E. Ohlstein, P. Nambi, 1998, Journal of cardiovascular pharmacology.

Solubilization of rat liver vasopressin receptors as a complex with a guanine-nucleotide-binding protein and phosphoinositide-specific phospholipase C.

M. Minnich, N. Aiyar, C. F. Bennett, 1989, The Biochemical journal.

Endothelin B receptor modulates inflammatory pain and cutaneous inflammation.

Z. Ao, S. Douglas, E. Ohlstein, 1999, Molecular pharmacology.

Solubilization of Vasopressin Receptors

S. Crooke, P. Nambi, N. Aiyar, 1991 .

Solubilization of a guanine nucleotide-sensitive form of vasopressin V2 receptors from porcine kidney.

M. Minnich, N. Aiyar, S. Crooke, 1989, Archives of biochemistry and biophysics.

Sensitization of frog erythrocyte adenylate cyclase system by tumor-promoting phorbol diesters.

D. Sibley, R. Lefkowitz, P. Nambi, 1985, Canadian journal of physiology and pharmacology.

Molecular characterization and regulation of the human endothelin receptors.

D. Bergsma, H. Wu, N. Elshourbagy, 1993, The Journal of biological chemistry.

Nonpeptide endothelin receptor antagonists: IV. Identification of receptors in rabbit colonic mucosa and smooth muscle and correlation with physiological effects.

E. Ohlstein, P. Nambi, P. Smith, 1995, Journal of Pharmacology and Experimental Therapeutics.

Identification and characterization of endothelin receptors on rat osteoblastic osteosarcoma cells: down-regulation by 1,25-dihydroxy-vitamin D3.

H. Wu, P. Nambi, U. Prabhakar, 1995, Molecular pharmacology.

Cloning and characterization of a novel endothelin receptor from Xenopus heart.

H. Wu, P. Nambi, C. Kumar, 1994, The Journal of biological chemistry.

Rat kidney endothelin receptors in ischemia-induced acute renal failure.

P. Nambi, M. Gellai, M. Pullen, 1993, The Journal of pharmacology and experimental therapeutics.

Identification of endothelin receptor subtypes in rat kidney cortex using subtype-selective ligands.

N. Aiyar, H. Wu, P. Nambi, 1992, Molecular pharmacology.

4-(3-Aryloxyaryl)quinoline sulfones are potent liver X receptor agonists.

Anna Wilhelmsson, P. Nambi, M. Evans, 2010, Bioorganic & medicinal chemistry letters.

Desensitization of the turkey erythrocyte beta-adrenergic receptor in a cell-free system. Evidence that multiple protein kinases can phosphorylate and desensitize the receptor.

D. Sibley, R. Lefkowitz, P. Nambi, 1985, The Journal of biological chemistry.

Synthesis of 4-(3-biaryl)quinoline sulfones as potent liver X receptor agonists.

Anna Wilhelmsson, James Jetter, P. Nambi, 2010, Bioorganic & medicinal chemistry letters.

Functional and binding characterization of endothelin receptors in human bronchus: evidence for a novel endothelin B receptor subtype?

P. Nambi, D. Hay, M. Pullen, 1998, The Journal of pharmacology and experimental therapeutics.

Inhibition of formation of cyclic AMP and cyclic GMP by vasopressin in smooth-muscle cells is insensitive to pertussis toxin.

N. Aiyar, S. Crooke, P. Nambi, 1988, The Biochemical journal.

Transient forebrain ischemia alters acutely endothelin receptor density and immunoreactivity in gerbil brain.

R. Willette, E. Ohlstein, P. Nambi, 1993, Life sciences.

Desensitization of turkey erythrocyte adenylate cyclase. Beta-adrenergic receptor phosphorylation is correlated with attenuation of adenylate cyclase activity.

D. Sibley, M. Caron, R. Lefkowitz, 1984, The Journal of biological chemistry.

Homologous and heterologous desensitization mediated by vasopressin in smooth muscle cells.

N. Aiyar, S. Crooke, P. Nambi, 1989, Cellular Signalling.

Induction of functional beta-adrenergic receptors in rat aortic smooth muscle cells by sodium butyrate.

S. Crooke, P. Nambi, D. Schmidt, 1986, Biochemical pharmacology.

Characterization of a novel porcine endothelin(B) receptor splice variant.

H. Wu, N. Elshourbagy, P. Nambi, 2000, The Journal of pharmacology and experimental therapeutics.

Endothelin receptor binding and cellular signal transduction in neurohybrid NG108-15 cells

H. Wu, T. Yue, G. Feuerstein, 1991, Neuroscience.

Effects of various concomitant medications on gastric alcohol dehydrogenase and the first-pass metabolism of ethanol.

R. Palmer, P. Nambi, J. Wetherington, 1991, The American journal of gastroenterology.

A novel radiolabeled vasopressin antagonist: [3H-Phe]-desGlyd(CH2)5D-Tyr(Et)VAVP, [3H]-SK&F 101926.

N. Aiyar, S. Crooke, P. Nambi, 1987, Molecular Pharmacology.

Desensitization of vasopressin sensitive adenylate cyclase by vasopressin and phorbol esters.

N. Aiyar, S. Crooke, P. Nambi, 1990, Cellular signalling.

Solubilization and reconstitution of vasopressin V1 receptors of rat liver.

N. Aiyar, S. Crooke, P. Nambi, 1987, Molecular Pharmacology.

Carboxylic acid based quinolines as liver X receptor modulators that have LXRbeta receptor binding selectivity.

Lisa Nogle, Anna Wilhelmsson, James Jetter, 2008, Bioorganic & medicinal chemistry letters.

Involvement of cAMP-dependent protein kinase and pertussis toxin-sensitive G-proteins in CGRP mediated JNK activation in human neuroblastoma cell line

N. Aiyar, N. Parameswaran, P. Nambi, 2000, Neuropeptides.

Tu-P8:325 Way-254011, a novel liver X receptor modulator, inhibitss atherosclerotic lesion progression in apolipoprotein E knockout mice

P. Nambi, J. Keith, Qiangyuan Liu, 2006 .

Identification and Function of Putative ETB Receptor Subtypes in the Dog Kidney

D. Brooks, P. Nambi, M. Gellai, 1995, Journal of Cardiovascular Pharmacology.

4-(3-aryloxyaryl)quinoline alcohols are liver X receptor agonists.

Anna Wilhelmsson, John Ullrich, P. Nambi, 2009, Bioorganic & medicinal chemistry.

Effect of sirolimus on the cholesterol content of aortic arch in ApoE knockout mice.

P. Nambi, S. Adelman, M. Basso, 2003, Transplantation proceedings.

Photoaffinity labeling of turkey erythrocyte beta-adrenergic receptors: degradation of the Mr = 49,000 protein explains apparent heterogeneity.

D. Sibley, M. Caron, R. Lefkowitz, 1984, Biochemical and biophysical research communications.

Proteolysis of skeletal muscle adenylate cyclase. Destruction and reconstitution of fluoride and guanylnucleotide sensitivity.

P. Nambi, G. Drummond, 1980, Biochimica et biophysica acta.

Identification of cardiac endothelin binding sites in rats: downregulation of left atrial endothelin binding sites in response to myocardial infarction.

E. F. Smith, P. Nambi, J. Egan, 1991, Pharmacology.

Transforming growth factor-beta-mediated proliferation of renal tubular epithelial cells involves pertussis toxin-sensitive G protein-and protein kinase C-dependent pathways.

P. Nambi, Hsiao-ling Wu, 1998, Pharmacology.

Targeted disruption of the endothelin-B-receptor gene attenuates inflammatory nociception and cutaneous inflammation in mice.

Z. Ao, S. Douglas, E. Ohlstein, 2000, Journal of cardiovascular pharmacology.