A. Bennett

发表

Differential role of beta(1C) and beta(1A) integrin cytoplasmic variants in modulating focal adhesion kinase, protein kinase B/AKT, and Ras/Mitogen-activated protein kinase pathways.

M. Fornaro, L. Languino, C. A. Steger, 2000, Molecular biology of the cell.

Different Signaling Roles of SHPTP2 in Insulin-induced GLUT1 Expression and GLUT4 Translocation (*)

M. Birnbaum, B. Neel, A. Bennett, 1995, The Journal of Biological Chemistry.

Mice lacking MKP-1 and MKP-5 Reveal Hierarchical Regulation of Regenerative Myogenesis.

D. Gerrard, A. Bennett, Hao Shi, 2015, Journal of stem cell and regenerative biology.

Regulation of distinct stages of skeletal muscle differentiation by mitogen-activated protein kinases.

N. Tonks, A. Bennett, 1997, Science.

MAP kinase phosphatase‐1 deficiency impairs skeletal muscle regeneration and exacerbates muscular dystrophy

B. Olwin, A. Bennett, R. Flach, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver.

G. Cline, B. Rothermel, A. Bennett, 2005, Diabetes.

Studies on the Effects of Peroxisome Proliferators as Novel Ca2+ Mobilizing Agents Using Indo-1-Loaded Hepatocytes

Gary M Williams, O. Flint, A. Bennett, 1993 .

Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras.

C. Walsh, B. Neel, A. Bennett, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Loss of MKP-5 promotes myofiber survival by activating STAT3/Bcl-2 signaling during regenerative myogenesis

A. Bennett, Kisuk Min, A. Lawan, 2017, Skeletal Muscle.

SH2 Domain‐Containing Phosphatase‐2 Is a Novel Antifibrotic Regulator in Pulmonary Fibrosis

Guoying Yu, V. Aidinis, N. Kaminski, 2017, American journal of respiratory and critical care medicine.

Mitogen-Activated Protein Kinases and Mitogen-Activated Protein Kinase Phosphatases in Regenerative Myogenesis and Muscular Dystrophy

A. Bennett, Hao Shi, 2012 .

Role of MKP-1 in osteoclasts and bone homeostasis.

A. Bennett, Fatih Mercan, W. Cui, 2009, The American journal of pathology.

Deletion of mitogen-activated protein kinase phosphatase 1 modifies the response to mechanical bone marrow ablation in a mouse model.

A. Bennett, Qing Zhang, A. Vignery, 2009, Comparative medicine.

Improved regenerative myogenesis and muscular dystrophy in mice lacking Mkp5.

R. Flavell, A. Bennett, C. Dong, 2013, The Journal of clinical investigation.

SHP-2 complex formation with the SHP-2 substrate-1 during C2C12 myogenesis.

A. Bennett, L. Zhang, X. Liu, 2001, Journal of cell science.

Calcium signaling in the nucleus.

M. Leite, A. Bennett, D. Gomes, 2006, Canadian journal of physiology and pharmacology.

Gain-of-function/Noonan syndrome SHP-2/Ptpn11 mutants enhance calcium oscillations and impair NFAT signaling

B. Ehrlich, M. Estrada, P. Uhlén, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Epidermal Growth Factor-mediated Activation of the ETS Domain Transcription Factor Elk-1 Requires Nuclear Calcium*

B. Ehrlich, T. Pusl, A. Bennett, 2002, The Journal of Biological Chemistry.

O-GlcNAc transferase suppresses necroptosis and liver fibrosis

Jun Yu, Dongjun Chung, Min-Dian Li, 2019, bioRxiv.

A Phosphoproteomic Screen Identifies a Guanine Nucleotide Exchange Factor for Rab3A Protein as a Mitogen-activated Protein (MAP) Kinase Phosphatase-5-regulated MAP Kinase Target in Interleukin 6 (IL-6) Secretion and Myogenesis*

A. Bennett, Hao Shi, Woochul Chang, 2017, The Journal of Biological Chemistry.

SHP-2 Regulates Cell Growth by Controlling the mTOR/S6 Kinase 1 Pathway*

J. Blenis, A. Bennett, H. Qin, 2007, Journal of Biological Chemistry.

Low-dose Dasatinib Ameliorates Hypertrophic Cardiomyopathy in Noonan Syndrome with Multiple Lentigines

A. Bennett, A. Vinks, Kana Mizuno, 2021, Cardiovascular Drugs and Therapy.

Differential Role of b 1C and b 1A Integrin Cytoplasmic Variants in Modulating Focal Adhesion Kinase, Protein Kinase B/AKT, and Ras/Mitogen-activated Protein Kinase Pathways

M. Fornaro, L. Languino, C. A. Steger, 2000 .

The Major Vault Protein Is a Novel Substrate for the Tyrosine Phosphatase SHP-2 and Scaffold Protein in Epidermal Growth Factor Signaling*

E. Wiemer, A. Bennett, S. Kolli, 2004, Journal of Biological Chemistry.

Tyrosyl phosphorylation of PZR promotes hypertrophic cardiomyopathy in PTPN11-associated Noonan syndrome with multiple lentigines.

A. Bennett, J. Yi, S. Perla, 2020, JCI insight.

Alteration of rat liver endoplasmic reticulum Ca(2+)-ATPase thiol integrity by ciprofibrate, a peroxisome proliferator.

G. Williams, A. Bennett, Anton M. Bennett, 1993, Biochemical pharmacology.

Reduction of rat liver endoplasmic reticulum Ca(2+)-ATPase activity and mobilization of hepatic intracellular calcium by ciprofibrate, a peroxisome proliferator.

G. Williams, A. Bennett, 1992, Biochemical pharmacology.

Improving Obesity and Insulin Resistance by Targeting Skeletal Muscle MKP-1

A. Bennett, A. Lawan, 2020, Journal of cellular signaling.

Novel Role for SHP-2 in Nutrient-Responsive Control of S6 Kinase 1 Signaling

A. Bennett, Fatih Mercan, Hojin Lee, 2012, Molecular and Cellular Biology.

JAK2 and SHP2 Reciprocally Regulate Tyrosine Phosphorylation and Stability of Proapoptotic Protein ASK1*

W. Min, Luyang Yu, Haifeng Zhang, 2009, Journal of Biological Chemistry.

Loss of Mitogen-activated Protein Kinase Phosphatase-1 Protects from Hepatic Steatosis by Repression of Cell Death-inducing DNA Fragmentation Factor A (DFFA)-like Effector C (CIDEC)/Fat-specific Protein 27*

A. Bennett, R. Flach, Lei Zhang, 2011, The Journal of Biological Chemistry.

Low-dose dasatinib rescues cardiac function in Noonan syndrome.

Ivana Y. Kuo, B. Ehrlich, A. Bennett, 2016, JCI insight.

Approaches to the Identification of Protein Tyrosine Phosphatase Substrates

A. Bennett, T. Tiganis, 2010 .

Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors.

J. Herrington, A. Bennett, J. Ellman, 2022, European journal of medicinal chemistry.

Epidermal Growth Factor Receptor and the Adaptor Protein p52 Shc Are Speciﬁc Substrates of T-Cell Protein Tyrosine Phosphatase

N. Tonks, K. Ravichandran, A. Bennett, 1998 .

Epidermal Growth Factor Receptor and the Adaptor Protein p 52 Shc Are Specific Substrates of T-Cell Protein Tyrosine Phosphatase

N. Tonks, K. Ravichandran, A. Bennett, 1998 .

The seventh international RASopathies symposium: Pathways to a cure—expanding knowledge, enhancing research, and therapeutic discovery

B. Korf, E. I. Pierpont, B. Gelb, 2022, American Journal of Medical Genetics. Part A.

Vanillic Acid Excretion during Stress

A. Bennett, P. Smith, 1958, Nature.

Analysis of Protein Tyrosine Phosphatases and Substrates

A. Bennett, Fatih Mercan, 2010, Current protocols in molecular biology.

Proliferating Lines of Rat Liver Epithelial Cells

Gary M Williams, A. Bennett, G. Williams, 1993 .

Inositol 1,4,5-trisphosphate receptor type II (InsP3R-II) is reduced in obese mice, but metabolic homeostasis is preserved in mice lacking InsP3R-II.

G. Shulman, B. Ehrlich, A. Bennett, 2014, American journal of physiology. Endocrinology and metabolism.

Inositol 1,4,5-trisphosphate receptor type II (InsP3R-II) is reduced in obese mice, but metabolic homeostasis is preserved in mice lacking InsP3R-II.

G. Shulman, B. Ehrlich, A. Bennett, 2014, American journal of physiology. Endocrinology and metabolism.

The imprinted H19 lncRNA antagonizes let-7 microRNAs.

Chaochun Liu, Wang Min, Jing Ma, 2013, Molecular cell.

Protein tyrosine phosphatase function: the substrate perspective.

A. Bennett, T. Tiganis, 2007, The Biochemical journal.

c-Met Must Translocate to the Nucleus to Initiate Calcium Signals*♦

P. Várnai, T. Balla, M. Leite, 2008, Journal of Biological Chemistry.

An Assessment of the Therapeutic Landscape for the Treatment of Heart Disease in the RASopathies

A. Bennett, J. Yi, S. Perla, 2022, Cardiovascular Drugs and Therapy.

Noonan Syndrome-Associated SHP2 Dephosphorylates GluN2B to Regulate NMDA Receptor Function

C. Greer, A. Koleske, A. Bennett, 2018, Cell reports.

PZR Coordinates Shp2 Noonan and LEOPARD Syndrome Signaling in Zebrafish and Mice

A. Heck, J. den Hertog, A. Bennett, 2014, Molecular and Cellular Biology.

PZR coordinates Noonan and LEOPARD syndrome signaling in zebrafish and mice

A. Heck, A. Bennett, C. Preisinger, 2014 .

Physiological signaling specificity by protein tyrosine phosphatases.

A. Bennett, M. Soulsby, 2009, Physiology.

Noonan Syndrome-associated SHP-2/Ptpn11 Mutants Enhance SIRPα and PZR Tyrosyl Phosphorylation and Promote Adhesion-mediated ERK Activation*

A. Bennett, S. Eminaga, Seda Eminaga, 2008, Journal of Biological Chemistry.

SHP-2 Positively Regulates Myogenesis by Coupling to the Rho GTPase Signaling Pathway

J. Settleman, M. Fornaro, A. Bennett, 2004, Molecular and Cellular Biology.

MAPK phosphatase-1 facilitates the loss of oxidative myofibers associated with obesity in mice.

G. Shulman, A. Bennett, V. Samuel, 2009, The Journal of clinical investigation.

SHP‐2 regulates the phosphatidylinositide 3′‐kinase/Akt pathway and suppresses caspase 3‐mediated apoptosis

M. Fornaro, A. Bennett, M. Kontaridis, 2004, Journal of cellular physiology.

A Novel Role of Vascular Endothelial Cadherin in Modulating c-Src Activation and Downstream Signaling of Vascular Endothelial Growth Factor*

A. Bennett, Z. Jin, C. Ha, 2008, Journal of Biological Chemistry.

Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression

B. Neel, R. Freeman, A. Bennett, 1996, Molecular and cellular biology.

Mining the function of protein tyrosine phosphatases in health and disease.

A. Bennett, Hojin Lee, Kisuk Min, 2015, Seminars in cell & developmental biology.

Diversity and specificity of the mitogen-activated protein kinase phosphatase-1 functions

A. Bennett, Hao Shi, Florian Gatzke, 2012, Cellular and Molecular Life Sciences.

Essential Role for Mitogen-activated Protein (MAP) Kinase Phosphatase-1 in Stress-responsive MAP Kinase and Cell Survival Signaling*

A. Bennett, J. Wu, J. J. Wu, 2005, Journal of Biological Chemistry.

Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor.

C. Walsh, B. Neel, S. Shoelson, 1993, The Journal of biological chemistry.

Role of SHP-2 in Fibroblast Growth Factor Receptor-Mediated Suppression of Myogenesis in C2C12 Myoblasts

Lei Zhang, A. Bennett, Lei Zhang, 2002, Molecular and Cellular Biology.

DUSPs, twists and turns in the Journey to Vascular Inflammation

A. Bennett, 2018, The FEBS journal.

Mitogen-activated protein kinase phosphatase-1 – a potential therapeutic target in metabolic disease

A. Bennett, Rachel J. Roth Flach, 2010, Expert opinion on therapeutic targets.

The MAP kinase phosphatase, MKP-1, regulates BDNF-induced axon branching

G. Miyoshi, M. Chao, A. Bennett, 2010, Nature Neuroscience.

MAP kinase phosphatase-1 - a new player at the nexus between sarcopenia and metabolic disease

A. Bennett, R. Flach, 2010, Aging.

Mice lacking MAP kinase phosphatase-1 have enhanced MAP kinase activity and resistance to diet-induced obesity.

P. Neufer, G. Shulman, A. Bennett, 2006, Cell metabolism.

Dynamic regulation of pro- and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses

H. Chi, R. Flavell, A. Bennett, 2006, Proceedings of the National Academy of Sciences of the United States of America.

The Noncatalytic Amino Terminus of Mitogen-Activated Protein Kinase Phosphatase 1 Directs Nuclear Targeting and Serum Response Element Transcriptional Regulation

A. Bennett, J. Wu, Lei Zhang, 2005, Molecular and Cellular Biology.

Calcium-dependent O-GlcNAc signaling drives liver autophagy in adaptation to starvation

Xiaoyong Yang, B. Ehrlich, A. Bennett, 2017, Genes & development.

Identification of receptor protein tyrosine phosphatases (RPTPs) as regulators of receptor tyrosine kinases (RTKs) using an RPTP siRNA-RTK substrate screen.

A. Bennett, Hojin Lee, 2015, Methods in molecular biology.

Receptor Protein Tyrosine Phosphatase-Receptor Tyrosine Kinase Substrate Screen Identifies EphA2 as a Target for LAR in Cell Migration

A. Bennett, Hojin Lee, 2013, Molecular and Cellular Biology.

Hepatic inositol 1,4,5 trisphosphate receptor type 1 mediates fatty liver

G. Shulman, Xiaoyong Yang, B. Ehrlich, 2016, Hepatology communications.

Nucleoplasmic Calcium Is Required for Cell Proliferation*

M. Leite, A. Bennett, Wayne M. Grant, 2007, Journal of Biological Chemistry.

The sixth international RASopathies symposium: Precision medicine—From promise to practice

G. Rumbaugh, K. Walsh, N. Rosen, 2019, American journal of medical genetics. Part A.

SHP-2 activates signaling of the nuclear factor of activated T cells to promote skeletal muscle growth

B. Neel, M. Fornaro, Wentian Yang, 2006, The Journal of cell biology.

Epidermal Growth Factor Receptor and the Adaptor Protein p52Shc Are Specific Substrates of T-Cell Protein Tyrosine Phosphatase

N. Tonks, K. Ravichandran, A. Bennett, 1998, Molecular and Cellular Biology.

A novel site on dual-specificity phosphatase MKP7/DUSP16 is required for catalysis and MAPK binding

A. Bennett, Lei Zhang, E. Lolis, 2022, The Journal of biological chemistry.

Diversity and specificity of the mitogen-activated protein kinase phosphatase-1 functions

A. Bennett, Hao Shi, Florian Gatzke, 2012, Cellular and Molecular Life Sciences.

Hepatic Mitogen-Activated Protein Kinase Phosphatase 1 Selectively Regulates Glucose Metabolism and Energy Homeostasis

G. Shulman, A. Bennett, J. Camporez, 2014, Molecular and Cellular Biology.

MAP Kinase Phosphatase-5 Deficiency Protects Against Pressure Overload-Induced Cardiac Fibrosis

W. Koch, Xinbo Zhang, E. Gao, 2021, Frontiers in Immunology.

The tyrosine phosphatase SHP2 regulates recovery of endothelial adherens junctions through control of β-catenin phosphorylation

D. Geerts, P. Hordijk, A. Bennett, 2012, Molecular biology of the cell.

An allosteric site on MKP5 reveals a strategy for small-molecule inhibition

K. Anderson, N. Kaminski, Xinbo Zhang, 2020, Science Signaling.

Role of dual-specificity protein phosphatase DUSP10/MKP-5 in pulmonary fibrosis

Guoying Yu, V. Aidinis, N. Kaminski, 2019, American Journal of Physiology-Lung Cellular and Molecular Physiology.

Mitogen-activated protein kinase phosphatase-1 (MKP-1): a critical regulator of innate immune responses

H. Chi, R. Flavell, A. Bennett, 2007 .

Mitogen-Activated Protein Kinase Phosphatases in Metabolism

A. Bennett, A. Lawan, 2013 .

Nuclear and cytosolic calcium are regulated independently

P. Koulen, B. Ehrlich, M. Leite, 2003, Proceedings of the National Academy of Sciences of the United States of America.

SH2 Domain-Containing Phosphatase-SHP2 Attenuates Fibrotic Responses through Negative Regulation of Mitochondrial Metabolism in Lung Fibroblasts

V. Aidinis, A. Bennett, Demosthenes Bouros, 2023, Diagnostics.

Peroxisome proliferation–associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity

M. Dietrich, T. Horvath, M. Shanabrough, 2011, Nature Medicine.

Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus.

O. Ibraghimov-Beskrovnaya, P. Igarashi, S. Somlo, 2004, The Journal of clinical investigation.

Skeletal Muscle–Specific Deletion of MKP-1 Reveals a p38 MAPK/JNK/Akt Signaling Node That Regulates Obesity-Induced Insulin Resistance

Yaohui Nie, G. Shulman, C. Fernández-Hernando, 2018, Diabetes.

Hepatocyte-specific miR-33 deletion attenuates NAFLD-NASH-HCC progression

L. Goedeke, Y. Suárez, C. Fernández-Hernando, 2023, bioRxiv.

O-GlcNAc transferase/host cell factor C1 complex regulates gluconeogenesis by modulating PGC-1α stability.

J. Yates, Lin Zhao, Min-Dian Li, 2012, Cell metabolism.

Teaching an old dog new tricks: A new tool for protein tyrosine phosphatase substrate discovery

A. Bennett, 2023, The Journal of biological chemistry.

Mitogen-Activated Protein Kinase Regulation in Hepatic Metabolism

A. Bennett, A. Lawan, 2017, Trends in Endocrinology & Metabolism.

Calcium as a permissive factor but not an initiation factor in DNA synthesis induction in cultured rat hepatocytes by the peroxisome proliferator ciprofibrate.

G. Williams, A. Bennett, 1993, Biochemical pharmacology.

Mitogen-Activated Protein Kinase Phosphatases: No Longer Undruggable?

A. Bennett, Shanelle R. Shillingford, 2023, Annual review of pharmacology and toxicology.