F. Marceau

发表

p 38 MAP kinase pathway regulates angiotensin II-induced contraction of rat vascular smooth muscle

S. Meloche, J. Landry, J. Huot, 2000 .

Lack of direct interaction between enalaprilat and the kinin B1 receptors

F. Marceau, G. Morissette, Jean-Philippe Couture, 2008, Peptides.

The kallikrein-kinin system: current and future pharmacological targets.

F. Marceau, N. Brown, N. Garbacki, 2005, Journal of pharmacological sciences.

NLRP3 promotes autophagy of urate crystals phagocytized by human osteoblasts

F. Marceau, P. Poubelle, I. Allaeys, 2013, Arthritis Research & Therapy.

Massive Cell Vacuolization Induced by Organic Amines Such as Procainamide

R. C.-Gaudreault, F. Marceau, E. Moreau, 2004, Journal of Pharmacology and Experimental Therapeutics.

The kallikrein-kininogen-kinin system: lessons from the quantification of endogenous kinins

J. Rouleau, F. Marceau, A. Adam, 2000, Peptides.

The contribution of angiotensin-converting enzyme (ACE) to the metabolism of kinins (bradykinin and des-Arg9-bradykinin) and effect of ACE inhibitors on their in vitro and in vivo metabolism

F. Marceau, A. Adam, C. Blais, 2001 .

High affinity capture and concentration of quinacrine in polymorphonuclear neutrophils via vacuolar ATPase-mediated ion trapping: comparison with other peripheral blood leukocytes and implications for the distribution of cationic drugs.

F. Marceau, C. Roy, Maria J. G. Fernandes, 2013, Toxicology and applied pharmacology.

Cation trapping by cellular acidic compartments: beyond the concept of lysosomotropic drugs.

F. Marceau, G. Morissette, R. Gaudreault, 2012, Toxicology and applied pharmacology.

Generation of kinins during preparation and storage of whole blood–derived platelet concentrates

R. Colman, F. Marceau, A. Désormeaux, 2007, Transfusion.

Met-Lys-bradykinin-Ser-Ser, a peptide produced by the neutrophil from kininogen, is metabolically activated by angiotensin converting enzyme in vascular tissue.

F. Marceau, C. Roy, A. Adam, 2011, Pharmacological research.

Altered frequency of a promoter polymorphism of the kinin B2 receptor gene in hypertensive African-Americans.

D. Bachvarov, F. Marceau, N. Brown, 2000, American journal of hypertension.

Characterization of two polymorphic sites in the human kinin B1 receptor gene: altered frequency of an allele in patients with a history of end-stage renal failure.

M. Landry, D. Bachvarov, F. Marceau, 1998, Journal of the American Society of Nephrology : JASN.

Altered frequency of a promoter polymorphic allele of the kinin B1 receptor gene in inflammatory bowel disease.

M. Landry, D. Bachvarov, F. Marceau, 1998, Gastroenterology.

The B1 receptors for kinins.

D. Bachvarov, J. Hess, F. Marceau, 1998, Pharmacological reviews.

Effect of allelic polymorphism of the B(1) and B(2) receptor genes on the contractile responses of the human umbilical vein to kinins.

M. Landry, D. Bachvarov, F. Marceau, 2000, The Journal of pharmacology and experimental therapeutics.

The degradation of bradykinin (BK) and of des-Arg9-BK in plasma.

F. Marceau, S. St.-Pierre, D. Regoli, 1981, Canadian journal of physiology and pharmacology.

Induction of beta 1-receptors for kinins in the rabbit by a bacterial lipopolysaccharide.

F. Marceau, D. Regoli, J. LaVigne, 1981, European journal of pharmacology.

Bifunctional ligands of the bradykinin B2 and B1 receptors: An exercise in peptide hormone plasticity

J. Fortin, F. Marceau, C. Roy, 2018, Peptides.

Kinin receptors in experimental inflammation.

F. Marceau, S. St.-Pierre, D. Regoli, 1980, Canadian journal of physiology and pharmacology.

Kinin B1 receptors: a review.

F. Marceau, 1995, Immunopharmacology.

Pharmacology of kinins: their relevance to tissue injury and inflammation.

F. Marceau, D. Regoli, J. Giroud, 1983, General pharmacology.

The kinin B1 receptor: an inducible G protein coupled receptor.

D. Bachvarov, F. Marceau, J. Larrivée, 1997, Canadian journal of physiology and pharmacology.

Cloning and pharmacological characterization of the rabbit bradykinin B2 receptor.

D. Bachvarov, F. Marceau, J. Larrivée, 1995, The Journal of pharmacology and experimental therapeutics.

C-C chemokine receptor-7 mediated endocytosis of antibody cargoes into intact cells

F. Marceau, G. Morissette, R. Lodge, 2013, Front. Pharmacol..

Mechanisms of action of antimalarials in inflammation: induction of apoptosis in human endothelial cells.

F. Marceau, E. Petitclerc, P. Poubelle, 1997, Journal of immunology.

Receptor-independent, vacuolar ATPase-mediated cellular uptake of histamine receptor-1 ligands: possible origin of pharmacological distortions and side effects.

F. Marceau, G. Morissette, R. Lodge, 2008, Toxicology and applied pharmacology.

Pharmacological profile of a bifunctional ligand of the formyl peptide receptor1 fused to the myc epitope.

F. Marceau, C. Roy, Maria J. G. Fernandes, 2015, International immunopharmacology.

Human interleukin‐1 induces a rapid relaxation of the rabbit isolated mesenteric artery

F. Marceau, E. Petitclerc, D. Deblois, 1991, British journal of pharmacology.

Effect of glucocorticoids, monokines and growth factors on the spontaneously developing responses of the rabbit isolated aorta to des‐Arg9‐bradykinin

F. Marceau, D. Deblois, J. Bouthillier, 1988, British journal of pharmacology.

In vivo protein‐DNA interactions at the kinin B1 receptor gene promoter: No modification on interleukin‐1 beta or lipopolysaccharide induction

D. Bachvarov, R. Drouin, F. Marceau, 2000, Journal of cellular biochemistry.

Induced by Tissue Injury Receptors 1 the Expression of the Kinin B Role of the Mitogen-Activated Protein Kinases in

D. Bachvarov, J. Landry, J. Huot, 1998 .

Role of the mitogen-activated protein kinases in the expression of the kinin B1 receptors induced by tissue injury.

D. Bachvarov, J. Landry, J. Huot, 1998, Journal of immunology.

Synergism between the contractile effect of epidermal growth factor and that of des‐Arg9‐bradykinin or of α.‐thrombin in rabbit aortic rings

F. Marceau, E. Petitclerc, D. Deblois, 1992, British journal of pharmacology.

Expression of kinin B1 receptor in fresh or cultured rabbit aortic smooth muscle: role of NF-κB

F. Marceau, G. Morissette, L. Lévesque, 2002 .

The Development of a Targeted and More Potent, Anti-Inflammatory Derivative of Colchicine: Implications for Gout.

G. Paré, F. Marceau, Philip Winter, 2020, Biochemical pharmacology.

A Nonpeptide Antagonist Reveals a Highly Glycosylated State of the Rabbit Kinin B1 Receptor

J. Fortin, F. Marceau, L. Gera, 2006, Molecular Pharmacology.

Effect of endogenous kinins, prostanoids, and NO on kinin B1 and B2 receptor expression in the rabbit.

D. Bachvarov, F. Marceau, J. Larrivée, 1999, American journal of physiology. Regulatory, integrative and comparative physiology.

Introduction: Natural product-based drug discovery in Immunopharmacology.

J. Talmadge, F. Marceau, F. Abe, 2016, International immunopharmacology.

Results Vascular Contractility Mediated by B 2 R in Rabbit Jugular Vein

D. Bachvarov, F. Marceau, J. Larrivée, 2000 .

Effect of endogenous kinins, prostanoids, and NO on kinin B1 and B2 receptor expression in the rabbit.

D. Bachvarov, F. Marceau, J. Larrivée, 1999, The American journal of physiology.

In Vivo Effects of Bradykinin B2 Receptor Agonists with Varying Susceptibility to Peptidases

F. Marceau, L. Gera, H. Bachelard, 2016, Front. Pharmacol..

Pharmacological evidence of bradykinin regeneration from extended sequences that behave as peptidase–activated B2 receptor agonists

F. Marceau, C. Roy, J. Bouthillier, 2014, Front. Pharmacol..

5 Drugs in the kallikrein-kinin system

F. Marceau, 2011 .

Effects of inactivation‐resistant agonists on the signalling, desensitization and down‐regulation of bradykinin B2 receptors

R. C.-Gaudreault, F. Marceau, A. Adam, 2009, British journal of pharmacology.

B-9972 (D-Arg-[Hyp3,Igl5,Oic7,Igl8]-bradykinin) Is an Inactivation-Resistant Agonist of the Bradykinin B2 Receptor Derived from the Peptide Antagonist B-9430 (D-Arg-[Hyp3,Igl5,D-Igl7,Oic8]-bradykinin): Pharmacologic Profile and Effective Induction of Receptor Degradation

J. Stewart, F. Marceau, G. Morissette, 2007, Journal of Pharmacology and Experimental Therapeutics.

Antagonist, partial agonist and antiproliferative actions of B‐9870 (CU201) as a function of the expression and density of the bradykinin B1 and B2 receptors

J. Stewart, F. Marceau, G. Morissette, 2007, British journal of pharmacology.

An in vitro reconstitution system to address the mechanism of the vascular expression of the bradykinin B₁ receptor in response to angiotensin converting enzyme inhibition.

F. Marceau, C. Roy, L. Gera, 2012, Vascular pharmacology.

Vascular mode of action of kinin B1 receptors and development of a cellular model for the investigation of these receptors

J. Grose, F. Marceau, F. Rioux, 1993, British journal of pharmacology.

Interleukin 8 (IL-8) induces the expression of kinin B1 receptor in human lung fibroblasts.

D. Bachvarov, F. Marceau, J. Larrivée, 1998, Biochemical and biophysical research communications.

De novo formation of vascular receptors for bradykinin.

F. Marceau, D. Regoli, J. Barabé, 1978, Canadian journal of physiology and pharmacology.

Quantification of des-Arg9-bradykinin using a chemiluminescence enzyme immunoassay: application to its kinetic profile during plasma activation.

F. Marceau, A. Adam, H. Ong, 1995, Journal of immunological methods.

In Vitro Pharmacological Profile of a New Small Molecule Bradykinin B2 Receptor Antagonist

F. Marceau, H. Ambrosi, A. Lesage, 2020, Frontiers in Pharmacology.

Bradykinin receptors: Agonists, antagonists, expression, signaling, and adaptation to sustained stimulation.

J. Fortin, F. Marceau, G. Morissette, 2020, International immunopharmacology.

D-Arg0-Bradykinin-Arg-Arg, a Latent Vasoactive Bradykinin B2 Receptor Agonist Metabolically Activated by Carboxypeptidases

F. Marceau, H. Bachelard, Xavier Charest-Morin, 2018, Front. Pharmacol..

Species-specific pharmacology of maximakinin, an amphibian homologue of bradykinin: putative prodrug activity at the human B2 receptor and peptidase resistance in rats

F. Marceau, H. Bachelard, Xavier Charest-Morin, 2017, PeerJ.

Effects of two novel non-peptide antagonists at the rabbit bradykinin B2 receptor

F. Marceau, P. Garratt, S. Houle, 2001, Peptides.

Non‐competitive pharmacological antagonism at the rabbit B1 receptor

J. Stewart, D. Bachvarov, F. Marceau, 2000, British journal of pharmacology.

Regulation of kinin‐induced contraction and DNA synthesis by inflammatory cytokines in the smooth muscle of the rabbit aorta

D. Bachvarov, F. Marceau, J. Larrivée, 1995, British journal of pharmacology.

S100A9 potentiates the activation of neutrophils by the etiological agent of gout, monosodium urate crystals

G. Paré, F. Marceau, P. Tessier, 2017, Journal of leukocyte biology.

Cloning and preliminary pharmacological characterization of the anaphylatoxin C5a receptor in the rabbit

D. Bachvarov, F. Marceau, S. St.-Pierre, 1999, British journal of pharmacology.

Hypotensive effects of Lys-des-Arg9-bradykinin and metabolically protected agonists of B1 receptors for kinins.

F. Marceau, D. Deblois, G. Drapeau, 1991, The Journal of pharmacology and experimental therapeutics.

Discovery of a Dual-Function Peptide That Combines Aminopeptidase N Inhibition and Kinin B1 Receptor Antagonism

J. Stewart, J. Fortin, F. Marceau, 2006, Journal of Pharmacology and Experimental Therapeutics.

A ligand-based approach to investigate the expression and function of angiotensin converting enzyme in intact human umbilical vein endothelial cells

F. Marceau, A. Adam, L. Gera, 2010, Peptides.

Prolonged signalling and trafficking of the bradykinin B2 receptor stimulated with the amphibian peptide maximakinin: insight into the endosomal inactivation of kinins.

F. Marceau, C. Roy, L. Gera, 2012, Pharmacological research.

Synthetic C5a receptor agonists. Pharmacology, metabolism and in vivo cardiovascular and hematologic effects.

F. Marceau, F. Rioux, D. Godin, 1993, Biochemical Pharmacology.

Effects of experimental conditions on the production of interleukin-1α and -1β by human endothelial cells cultured in vitro

F. Marceau, J. Grassi, Y. Frobert, 1992 .

Studies on the induction of pharmacological responses to des‐Arg9‐bradykinin in vitro and in vivo

F. Marceau, D. Deblois, J. Bouthillier, 1987, British journal of pharmacology.

Autophagic flux inhibition and lysosomogenesis ensuing cellular capture and retention of the cationic drug quinacrine in murine models

F. Marceau, J. Bouthillier, Xavier Charest-Morin, 2015, PeerJ.

Vacuolar ATPase-Mediated Cellular Concentration and Retention of Quinacrine: A Model for the Distribution of Lipophilic Cationic Drugs to Autophagic Vacuoles

F. Marceau, G. Morissette, J. Bouthillier, 2009, Drug Metabolism and Disposition.

Effects of the C5a anaphylatoxin and its relationship to cyclo‐oxygenase metabolites in rabbit vascular strips

F. Marceau, T. Hugli, 1985, British journal of pharmacology.

Cardiovascular expression of inflammatory signaling molecules, the kinin B1 receptor and COX2, in the rabbit: Effects of LPS, anti-inflammatory and anti-hypertensive drugs

F. Marceau, A. Désormeaux, A. Adam, 2008, Regulatory Peptides.

Role of Nuclear Factor-κB and Protein Kinase C Signaling in the Expression of the Kinin B1 Receptor in Human Vascular Smooth Muscle Cells

F. Marceau, G. Morissette, A. Adam, 2007, Molecular Pharmacology.

Role of Nuclear Factor- (cid:1) B and Protein Kinase C Signaling in the Expression of the Kinin B 1 Receptor in Human Vascular Smooth Muscle Cells

F. Marceau, G. Morissette, M. Moreau, 2007 .

Pharmacological modulation of the up-regulated responses to des-Arg9-bradykinin in vivo and in vitro.

F. Marceau, D. Deblois, J. Bouthillier, 1989, Immunopharmacology.

Fluorescent Ligands of the Bradykinin B1 Receptors: Pharmacologic Characterization and Application to the Study of Agonist-Induced Receptor Translocation and Cell Surface Receptor Expression

J. Stewart, F. Marceau, G. Morissette, 2009, Journal of Pharmacology and Experimental Therapeutics.

Design of Fluorescent Bradykinin Analogs: Application to Imaging of B2 Receptor-Mediated Agonist Endocytosis and Trafficking and Angiotensin-Converting Enzyme

F. Marceau, C. Roy, L. Gera, 2011, Journal of Pharmacology and Experimental Therapeutics.

Pulse exposure to protein synthesis inhibitors enhances vascular responses to des‐Arg9‐bradykinin: possible role of interleukin‐1

F. Marceau, D. Deblois, J. Bouthillier, 1991, British journal of pharmacology.

Structure and genomic organization of the human B1 receptor gene for kinins (BDKRB1).

D. Bachvarov, J. Hess, F. Marceau, 1996, Genomics.

Inhibition of human and rabbit arterial smooth muscle cell migration mediated by the kinin B1 receptor: role of receptor density and released mediators.

F. Marceau, G. Morissette, A. Adam, 2006, Canadian journal of physiology and pharmacology.

Contractile Effect of Anaphylatoxin C5a and of a Mimetic Peptide on the Human Umbilical Artery: Further Evidence for Leukocyte-Dependent Vasomotion

J. Fortin, F. Marceau, S. St.-Pierre, 2002, Journal of cardiovascular pharmacology.

Effects of experimental conditions on the production of interleukin-1 alpha and -1 beta by human endothelial cells cultured in vitro.

F. Marceau, J. Grassi, Y. Frobert, 1992, International journal of immunopharmacology.

Characterization of a fluorescent conjugate of the rabbit angiotensin AT1 receptor

J. Fortin, D. Bachvarov, F. Marceau, 2003, British journal of pharmacology.

Pharmacological modulation of interleukin 1 production by cultured endothelial cells from human umbilical veins.

F. Marceau, J. Grassi, P. Poubelle, 1990, Immunopharmacology.

Therapeutic options in inflammatory bowel disease: experimental evidence of a beneficial effect of kinin B1 receptor blockade

F. Marceau, D. Regoli, 2008, British journal of pharmacology.

Loss of function of vascular smooth muscle cells by nitric oxide‐dependent and ‐independent interactions with tumorigenic cells

F. Marceau, G. Morissette, E. Petitclerc, 2004, International journal of cancer.

Agonist-induced translocation of the kinin B(1) receptor to caveolae-related rafts.

D. Bachvarov, F. Marceau, T. Sabourin, 2002, Molecular pharmacology.

Lysosomotropic cationic drugs induce cytostatic and cytotoxic effects: Role of liposolubility and autophagic flux and antagonism by cholesterol ablation.

F. Marceau, Alexandre Parks, 2016, Toxicology and applied pharmacology.

Human kallikrein hK2 has low kininogenase activity while prostate-specific antigen (hK3) has none.

F. Marceau, C. Lazure, D. Deperthes, 1997, Biochimica et biophysica acta.

In Vitro Modeling of Bradykinin-Mediated Angioedema States

F. Marceau, J. Hébert, G. Rivard, 2020, Pharmaceuticals.

Measurement of Bradykinin Formation and Degradation in Blood Plasma: Relevance for Acquired Angioedema Associated With Angiotensin Converting Enzyme Inhibition and for Hereditary Angioedema Due to Factor XII or Plasminogen Gene Variants

F. Marceau, J. Hébert, K. Binkley, 2020, Frontiers in Medicine.

Rapid assay of human plasma carboxypeptidase N by high-performance liquid chromatographic separation of hippuryl-lysine and its product.

F. Marceau, S. St.-Pierre, A. Lussier, 1983, Journal of chromatography.

Characterization of a polymorphism in the coding region of the human C5a anaphylatoxin receptor

D. Bachvarov, F. Marceau, J. Bergeron, 1999, Immunogenetics.

Evidence for vascular tone regulation by resident or infiltrating leukocytes.

F. Marceau, François Marceau, 1996, Biochemical pharmacology.

expression in cultured cells intracellular retention and regulation of surface Studies on rabbit natural and recombinant tissue factors

J. Fortin, F. Marceau, A. Adam, 2016 .

Studies on rabbit natural and recombinant tissue factors: intracellular retention and regulation of surface expression in cultured cells.

J. Fortin, F. Marceau, A. Adam, 2005, American journal of physiology. Heart and circulatory physiology.

A Novel Nonpeptide Antagonist of the Kinin B1 Receptor: Effects at the Rabbit Receptor

J. Fortin, F. Marceau, G. Morissette, 2004, Journal of Pharmacology and Experimental Therapeutics.

Kininases and vascular responses to kinins.

F. Marceau, S. St.-Pierre, D. Regoli, 1982, European journal of pharmacology.

Cardiovascular effects of Sar-[D-Phe8]des-Arg9-bradykinin, a metabolically protected agonist of B1 receptor for kinins, in the anesthetized rabbit pretreated with a sublethal dose of bacterial lipopolysaccharide.

F. Marceau, F. Rioux, R. Audet, 1997, The Journal of pharmacology and experimental therapeutics.

Vascular smooth muscle contractility assays for inflammatory and immunological mediators.

J. Fortin, F. Marceau, G. Morissette, 2010, International immunopharmacology.

Inflammatory hyperalgesia induced by zymosan in the plantar tissue of the rat: effect of kinin receptor antagonists.

M. Landry, D. Bachvarov, F. Marceau, 2000, Immunopharmacology.

Development of a binding assay for the B1 receptors for kinins.

F. Marceau, F. Rioux, L. Lévesque, 1995, Immunopharmacology.

Wortmannin alters the intracellular trafficking of the bradykinin B2 receptor: role of phosphoinositide 3-kinase and Rab5.

F. Marceau, S. Houle, 2003, The Biochemical journal.

Cardiovascular actions of kinins in the rabbit.

F. Marceau, D. Regoli, B. Thériault, 1979, Canadian journal of physiology and pharmacology.

The rabbit mesenteric vein: a specific bioassay for substance P.

F. Marceau, A. Bérubé, D. Regoli, 1978, Canadian journal of physiology and pharmacology.

Bradykinin B₂ receptor-mediated transport into intact cells: anti-receptor antibody-based cargoes.

F. Marceau, G. Morissette, R. Lodge, 2011, European journal of pharmacology.

Dissociation of the vacuolar and macroautophagic cytopathology from the cytotoxicity induced by the lipophilic local anesthetic bupivacaine.

F. Marceau, G. Morissette, Marie-Thérèse Bawolak, 2011, Canadian journal of physiology and pharmacology.

Vacuolar ATPase-mediated sequestration of local anesthetics in swollen macroautophagosomes

F. Marceau, G. Morissette, Marie-Thérèse Bawolak, 2010, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

Intense pseudotransport of a cationic drug mediated by vacuolar ATPase: procainamide-induced autophagic cell vacuolization.

F. Marceau, G. Morissette, R. Lodge, 2008, Toxicology and applied pharmacology.

A Robust Bioassay of the Human Bradykinin B2 Receptor That Extends Molecular and Cellular Studies: The Isolated Umbilical Vein

F. Marceau, H. Bachelard, 2020, Pharmaceuticals.

The bradykinin B2 receptor antagonist icatibant (Hoe 140) blocks aminopeptidase N at micromolar concentrations: off-target alterations of signaling mediated by the bradykinin B1 and angiotensin receptors.

J. Fortin, F. Marceau, A. Adam, 2006, European journal of pharmacology.

Endogenous Aminopeptidase N Decreases the Potency of Peptide Agonists and Antagonists of the Kinin B1 Receptors in the Rabbit Aorta

J. Stewart, J. Fortin, F. Marceau, 2005, Journal of Pharmacology and Experimental Therapeutics.

The isolated human umbilical vein as a bioassay for kinin-generating proteases: An in vitro model for therapeutic angioedema agents.

A. Raghavan, F. Marceau, G. Rivard, 2016, Life sciences.

Bradykinin B2 receptor gene polymorphism is associated with altered urinary albumin/creatinine values in diabetic patients.

D. Bachvarov, F. Marceau, P. Maheux, 2002, Canadian journal of physiology and pharmacology.

A non-peptide antagonist unusually selective for the human form of the bradykinin B2 receptor.

J. Fortin, F. Marceau, G. Morissette, 2003, International immunopharmacology.

Expression of Metallopeptidases and Kinin Receptors in Swine Oropharyngeal Tissues: Effects of Angiotensin I-Converting Enzyme Inhibition and Inflammation

F. Marceau, A. Adam, W. Müller-Esterl, 2005, Journal of Pharmacology and Experimental Therapeutics.

Expression of metallopeptidases and kinin receptors in swine oropharyngeal tissues : effects of ACE inhibition and inflammation

F. Marceau, A. Adam, W. Müller-Esterl, 2005 .

Molecular identification and pharmacological profile of the bovine kinin B1 receptor

F. Marceau, G. Morissette, 2006, Biological chemistry.

Angiotensin converting enzyme inhibitor induced angio‐oedema: a review of the pathophysiology and risk factors

F. Marceau, E. Grouzmann, M. Lippmann, 2009, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

International Union of Pharmacology. XLV. Classification of the Kinin Receptor Family: from Molecular Mechanisms to Pathophysiological Consequences

F. Marceau, W. Müller-Esterl, L. M. Leeb-Lundberg, 2005, Pharmacological Reviews.

NTPDase1 (CD39) controls nucleotide-dependent vasoconstriction in mouse.

F. Marceau, J. Sévigny, G. Kauffenstein, 2010, Cardiovascular research.

N-Substituted 4-Aminobenzamides (Procainamide Analogs): An Assessment of Multiple Cellular Effects Concerning Ion Trapping

R. C.-Gaudreault, F. Marceau, E. Moreau, 2005, Molecular Pharmacology.

Mode of action of thrombin in the rabbit aorta

F. Marceau, F. Rioux, D. Godin, 1995, British journal of pharmacology.

Aminopeptidase modulation of the pharmacological responses to synthetic thrombin receptor agonists.

F. Marceau, F. Rioux, D. Godin, 1994, European journal of pharmacology.

Pharmacological characterization of the vascular permeability enhancing effects of kinins in the rabbit skin.

F. Marceau, D. Regoli, M. Knap, 1981, Canadian journal of physiology and pharmacology.

Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cells.

J. Landry, J. Huot, F. Houle, 1997, Circulation research.

Bradykinin receptor ligands: therapeutic perspectives

F. Marceau, D. Regoli, François Marceau, 2004, Nature Reviews Drug Discovery.

Dissociation of the antimicrobial activity of bacitracin USP from its renovascular effects

F. Marceau, E. Petitclerc, A. Toulouse, 1992, Antimicrobial Agents and Chemotherapy.

Recombinant Human Hemoglobin (rHb1.1) Selectively Inhibits Vasorelaxation Elicited by Nitric Oxide Donors in Rabbit Isolated Aortic Rings

F. Marceau, F. Rioux, G. Drapeau, 1995, Journal of cardiovascular pharmacology.

Recombinant human hemoglobin inhibits both constitutive and cytokine-induced nitric oxide-mediated relaxation of rabbit isolated aortic rings.

F. Marceau, R. Fielding, E. Petitclerc, 1994, Journal of cardiovascular pharmacology.

Abstracts from the 10th C1-inhibitor deficiency workshop

William H. Yang, A. Szilágyi, M. Margaglione, 2017, Allergy, Asthma & Clinical Immunology.

In vitro pharmacological profile of PHA-022121, a small molecule bradykinin B2 receptor antagonist in clinical development.

F. Marceau, E. Pardali, H. Ambrosi, 2022, International immunopharmacology.

Picomolar Sensitivity Analysis of Multiple Bradykinin-Related Peptides in the Blood Plasma of Patients With Hereditary Angioedema in Remission: A Pilot Study

F. Marceau, J. Hébert, G. Rivard, 2022, Frontiers in Allergy.

Increased fibrinolysis-induced bradykinin formation in hereditary angioedema confirmed using stored plasma and biotechnological inhibitors

F. Marceau, J. Hébert, G. Rivard, 2019, BMC Research Notes.

Comparing Pathways of Bradykinin Formation in Whole Blood From Healthy Volunteers and Patients With Hereditary Angioedema Due to C1 Inhibitor Deficiency

F. Marceau, J. Hébert, A. Bonnefoy, 2018, Front. Immunol..

Kinin receptors

D. Bachvarov, F. Marceau, 1998, Clinical reviews in allergy & immunology.

Trapping of adrenergic decongestant drugs into cellular endomembrane compartments: toxicological and pharmacological consequences.

F. Marceau, G. Morissette, J. Bouthillier, 2007, International immunopharmacology.

Mechanism of the contractile effect of diaspirin-cross-linked hemoglobin in rat isolated aorta strip denuded of endothelium as revealed using an oil-immersion procedure.

F. Marceau, K. Burhop, F. Rioux, 1996, Canadian journal of physiology and pharmacology.

Dual antagonists of the bradykinin B1 and B2 receptors based on a postulated common pharmacophore from existing non-peptide antagonists

F. Marceau, G. Morissette, J. Bouthillier, 2006, Biological chemistry.

Bradykinin B(2) receptor endocytosis, recycling, and down-regulation assessed using green fluorescent protein conjugates.

D. Bachvarov, F. Marceau, A. Adam, 2001, The Journal of pharmacology and experimental therapeutics.

C5a receptor antagonism coming of age for vascular pathology.

F. Marceau, E. Petitclerc, 2022, International immunopharmacology.

8 – Kinin B1 Receptor Induction and Inflammination

F. Marceau, 1997 .

p38 MAP kinase pathway regulates angiotensin II-induced contraction of rat vascular smooth muscle.

S. Meloche, J. Landry, J. Huot, 2000, American journal of physiology. Heart and circulatory physiology.

Effect of interferon-γ on inflammatory cytokine-induced bradykinin B1 receptor expression in human vascular cells.

F. Marceau, A. Adam, G. Koumbadinga, 2010, European journal of pharmacology.

Tumor cells expressing tissue factor influence the migration of smooth muscle cells in a catalytic activity-dependent way.

J. Fortin, F. Marceau, G. Morissette, 2009, Canadian journal of physiology and pharmacology.

Does zaltoprofen antagonize the bradykinin receptors?

F. Marceau, Marie-Thérèse Bawolak, 2007, Regulatory Peptides.

Pharmacological effects of recombinant human tissue kallikrein on bradykinin B2 receptors

A. Raghavan, F. Marceau, T. Kolodka, 2015, Pharmacology research & perspectives.

Bacitracin U.S.P. contains a factor that stimulates receptors for 5-hydroxytryptamine on rabbit aortic strips.

F. Marceau, D. Deblois, J. Bouthillier, 1990, Life sciences.

Bradykinin receptors in GtoPdb v.2021.3

F. Marceau, W. Müller-Esterl, R. Couture, 2021, IUPHAR/BPS Guide to Pharmacology CITE.

Development and in vivo evaluation of metabolically resistant antagonists of B1 receptors for kinins.

F. Marceau, D. Godin, L. Lévesque, 1993, The Journal of pharmacology and experimental therapeutics.

Effects of peptide and nonpeptide antagonists of bradykinin B2 receptors on the venoconstrictor action of bradykinin.

F. Marceau, J. Salvino, D. Sawutz, 1994, The Journal of pharmacology and experimental therapeutics.

Absence of ligand‐induced regulation of kinin receptor expression in the rabbit

D. Bachvarov, F. Marceau, S. Houle, 2001, British journal of pharmacology.

Bradykinin forming capacity of oversulfated chondroitin sulfate contaminated heparin in vitro.

D. Keire, F. Marceau, N. Brown, 2010, Biomaterials.

Altered cardiac bradykinin metabolism in experimental diabetes caused by the variations of angiotensin-converting enzyme and other peptidases

F. Marceau, A. Adam, H. Bachelard, 2010, Neuropeptides.

Kinin receptors: functional aspects.

J. Fortin, F. Marceau, A. Adam, 2002, International immunopharmacology.

Carboxypeptidase N (kininase I) activity in blood and synovial fluid from patients with arthritis.

F. Marceau, P. Poubelle, A. Beaulieu, 1987, Life sciences.

A tagged parathyroid hormone derivative as a carrier of antibody cargoes transported by the G protein coupled PTH1 receptor

J. Fortin, F. Marceau, P. Poubelle, 2014, Peptides.

Production and evaluation of parathyroid hormone receptor1 ligands with intrinsic or assembled peroxidase domains

F. Marceau, P. Poubelle, Xavier Charest-Morin, 2017, Scientific Reports.

Drugs of the Kallikrein–Kinin System: An Overview

F. Marceau, 2023, Drugs and Drug Candidates.

The ability of des-Arg9-bradykinin to relax rabbit isolated mesenteric arteries is acquired during in vitro incubation.

F. Marceau, D. Deblois, 1987, European journal of pharmacology.

Selective induction of cardiovascular responses to des-Arg9-bradykinin by bacterial endotoxin.

F. Marceau, S. St.-Pierre, A. Lussier, 1984, Pharmacology.

Effects of interleukin-1 receptor antagonist on three types of responses to interleukin-1 in rabbit isolated blood vessels.

F. Marceau, E. Petitclerc, D. Deblois, 1992, Journal of cardiovascular pharmacology.

Tissue Kallikrein Actions at the Rabbit Natural or Recombinant Kinin B2 Receptors

F. Marceau, A. Adam, G. Molinaro, 2003, Hypertension.

1 An in vitro reconstitution system to address the mechanism of the vascular expression of the bradykinin B 1 receptor in response to angiotensin converting enzyme inhibition

F. Marceau, C. Roy, L. Gera, 2017 .

Structural modification of the highly potent peptide bradykinin B1 receptor antagonist B9958.

J. Stewart, J. Fortin, F. Marceau, 2008, International immunopharmacology.

High agonist-independent clearance of rabbit kinin B1 receptors in cultured cells.

J. Fortin, F. Marceau, J. Bouthillier, 2003, American journal of physiology. Heart and circulatory physiology.

Further analysis of the upregulation of bradykinin B1 receptors in isolated rabbit aorta by using metabolic inhibitors.

F. Marceau, E. Petitclerc, F. Rioux, 1994, European journal of pharmacology.

Receptor tyrosine kinases as mediators of injury-induced bradykinin B1 receptor expression in rabbit aortic smooth muscle.

F. Marceau, A. Adam, E. Petitclerc, 2009, European journal of pharmacology.

Rapid protein synthesis and turnover is involved in interleukin-1-induced relaxation of the rabbit isolated mesenteric artery. Analysis of the arachidonate cascade.

F. Marceau, E. Petitclerc, P. Poubelle, 1994, The Journal of pharmacology and experimental therapeutics.

Epidermal growth factor-induced rapid relaxation of the isolated rabbit mesenteric artery.

F. Marceau, E. Petitclerc, P. Poubelle, 1994, European Journal of Pharmacology.

Assessment of cation trapping by cellular acidic compartments.

F. Marceau, C. Roy, J. Bouthillier, 2014, Methods in enzymology.

Biotechnological Fluorescent Ligands of the Bradykinin B1 Receptor: Protein Ligands for a Peptide Receptor

F. Marceau, Xavier Charest-Morin, 2016, PloS one.

A tagged parathyroid hormone derivative as a carrier of antibody cargoes transported by the G protein coupled PTH1 receptor

J. Fortin, F. Marceau, P. Poubelle, 2014, Peptides.

Antagonist-induced intracellular sequestration of rabbit bradykinin B(2) receptor.

D. Bachvarov, F. Marceau, J. Larrivée, 2000, Hypertension.

Inhibitory effects of cytoskeleton disrupting drugs and GDP-locked Rab mutants on bradykinin B₂ receptor cycling.

F. Marceau, C. Roy, R. Gaudreault, 2013, Pharmacological research.

N-terminal extended conjugates of the agonists and antagonists of both bradykinin receptor subtypes: Structure–activity relationship, cell imaging using ligands conjugated with fluorophores and prospect for functionally active cargoes

F. Marceau, C. Roy, L. Gera, 2012, Peptides.