G. Baffet

发表

The Mitogen-Activated Protein Kinase Kinase/Extracellular Signal-Regulated Kinase Cascade Activation Is a Key Signalling Pathway Involved in the Regulation of G1 Phase Progression in Proliferating Hepatocytes

C. Rescan, C. Guguen-Guillouzo, G. Zanninelli, 1999, Molecular and Cellular Biology.

GATA-1 is essential in EGF-mediated induction of nucleotide excision repair activity and ERCC1 expression through ERK2 in human hepatoma cells.

A. Guillouzo, G. Baffet, Lise O Andrieux, 2007, Cancer research.

ADAM12 in human liver cancers: TGF‐β‐regulated expression in stellate cells is associated with matrix remodeling

G. Baffet, O. Musso, B. Clement, 2003, Hepatology.

Fibrillar collagen scoring by second harmonic microscopy: a new tool in the assessment of liver fibrosis.

Christophe Odin, Bruno Turlin, Yann Le Grand, 2010, Journal of hepatology.

Orientation fields of nonlinear biological fibrils by second harmonic generation microscopy

G. Baffet, A. Renault, Y. Le Grand, 2008, Journal of microscopy.

Maintenance and reversibility of active albumin secretion by adult rat hepatocytes co-cultured with another liver epithelial cell type.

A. Guillouzo, C. Beaumont, C. Guguen-Guillouzo, 1983, Experimental cell research.

Molecular and tissue alterations of collagens in fibrosis.

S. Ricard-Blum, G. Baffet, N. Théret, 2018, Matrix biology : journal of the International Society for Matrix Biology.

RNAs containing mitochondrial ND6 and COI sequences present an abnormal structure in chemically induced rat hepatomas.

A. Kitzis, C. Guguen-Guillouzo, G. Baffet, 1989, Nucleic acids research.

ERK2 but not ERK1 plays a key role in hepatocyte replication: An RNAi‐mediated ERK2 knockdown approach in wild‐type and ERK1 null hepatocytes

J. Pouysségur, G. Pagès, G. Baffet, 2007, Hepatology.

The MAPK MEK 1 / 2-ERK 1 / 2 Pathway and Its Implication in Hepatocyte Cell Cycle Control

G. Baffet, C. Frémin, J. Guégan, 2013 .

Human T lymphocytes bioactivate heterocyclic aromatic amines by forming DNA adducts

G. Baffet, L. Vernhet, S. Langouët, 2016, Environmental and molecular mutagenesis.

The association of statins and taxanes: an efficient combination trigger of cancer cell apoptosis

B. Simon, L. Corcos, C. Le Jossic-Corcos, 2012, British Journal of Cancer.

MEK1/2 Overactivation Can Promote Growth Arrest by Mediating ERK1/2‐Dependent Phosphorylation of p70S6K

G. Baffet, S. Langouët, F. Ezan, 2014, Journal of cellular physiology.

Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42–Tuba pathway

Lisa Paysan, F. Saltel, V. Moreau, 2014, The Journal of cell biology.

MAPK signaling in cisplatin-induced death: predominant role of ERK1 over ERK2 in human hepatocellular carcinoma cells.

G. Baffet, S. Langouët, N. Théret, 2013, Carcinogenesis.

Growth factor dependence of progression through G1 and S phases of adult rat hepatocytes in vitro. Evidence of a mitogen restriction point in mid-late G1.

C. Guguen-Guillouzo, M. Bilodeau, P. Loyer, 1996, The Journal of biological chemistry.

Expression of coagulation factor V gene by normal adult human hepatocytes in primary culture

C. Guguen-Guillouzo, G. Baffet, B. Launois, 1991, British journal of haematology.

Aryl hydrocarbon receptor activation and cytochrome P450 1A induction by the mitogen-activated protein kinase inhibitor U0126 in hepatocytes.

A. Guillouzo, F. Guengerich, G. Baffet, 2004, Molecular pharmacology.

Aryl hydrocarbon receptor activation and cytochrome P450 1A induction by the mitogen-activated protein kinase inhibitor U0126 in hepatocytes.

A. Guillouzo, F. Guengerich, G. Baffet, 2004, Molecular pharmacology.

Hepatocytes may produce laminin in fibrotic liver and in primary culture

A. Guillouzo, G. Baffet, B. Clement, 1988, Hepatology.

Chronic iron overload inhibits protein secretion by adult rat hepatocytes maintained in long-term primary culture.

G. Lescoat, M. Rissel, P. Brissot, 1989, European journal of cell biology.

Immunocytochemical evidence for the maintenance of cytochrome P-450 isozymes, NADPH cytochrome C reductase, and epoxide hydrolase in pure and mixed primary cultures of adult human hepatocytes.

M. Rissel, A. Guillouzo, F. Guengerich, 1986, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

In vitro long term differentiation and functionality of three-dimensional bioprinted primary human hepatocytes: application for in vivo engraftment

G. Baffet, S. Langouët, V. Legagneux, 2022, Biofabrication.

PI3K‐FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival

D. Gilot, C. Rescan, C. Guguen-Guillouzo, 2002, Hepatology.

Production of interleukin 6 by hepatoma cells.

M. Hattori, G. Baffet, J. Gauldie, 1990, Molecular biology & medicine.

MEK/ERK‐dependent uPAR expression is required for motility via phosphorylation of P70S6K in human hepatocarcinoma cells

G. Baffet, A. Bessard, F. Ezan, 2007, Journal of cellular physiology.

Skp2 induction and phosphorylation is associated with the late G1 phase of proliferating rat hepatocytes

C. Rescan, C. Guguen-Guillouzo, M. Bilodeau, 1999, FEBS letters.

Role of Oncogenes in Hepatocarcinogenesis

C. Guguen-Guillouzo, D. Glaise, G. Baffet, 1988 .

An MLCK‐dependent window in late G1 controls S phase entry of proliferating rodent hepatocytes via ERK‐p70S6K pathway

C. Rescan, G. Baffet, A. Bessard, 2006, Hepatology.

Multiple division cycles and long‐term survival of hepatocytes are distinctly regulated by extracellular signal‐regulated kinases ERK1 and ERK2

D. Gilot, J. Pouysségur, G. Pagès, 2009, Hepatology.

Autocrine activity of interleukin 6 secreted by hepatocarcinoma cell lines.

G. Baffet, J. Gauldie, G. Fey, 1991, Molecular biology & medicine.

Deferoxamine arrests in vitro the proliferation of porcine hepatocyte in G1 phase of the cell cycle.

G. Lescoat, B. Drénou, P. Brissot, 2008, Liver.

Determination of extracellular matrix collagen fibril architectures and pathological remodeling by polarization dependent second harmonic microscopy

J. Bellanger, G. Baffet, E. Schaub, 2017, Scientific Reports.

Regulation and role of p21 and p27 cyclin-dependent kinase inhibitors during hepatocyte differentiation and growth.

D. Gilot, C. Guguen-Guillouzo, D. Glaise, 2003, American journal of physiology. Gastrointestinal and liver physiology.

Incerase of cell surface hyaluronic acid during aging in human liver cells

A. Guillouzo, G. Baffet, M. Aubery, 1982, Mechanisms of Ageing and Development.

Differential expression of laminin chains and receptor (LBP-32) in fetal and neoplastic hepatocytes compared to normal adult hepatocytes in vivo and in culture.

A. Guillouzo, C. Guguen-Guillouzo, G. Baffet, 1990, The American journal of pathology.

Modulation of alkaline phosphodiesterase I in cultured rat hepatocytes.

M. Rissel, A. Guillouzo, G. Baffet, 1987, Biochimica et biophysica acta.

Biosynthesis of factor V by normal adult rat hepatocytes.

C. Guguen-Guillouzo, G. Baffet, R. Eloy, 1989, Thrombosis research.

RNAi-mediated ERK2 knockdown inhibits growth of tumor cells in vitro and in vivo

G. Baffet, A. Fautrel, A. Bessard, 2008, Oncogene.

Synthesis and phosphorylation of cytoskeleton components in foetal, regenerating and adult normal rat hepatocytes during culture

G. Baffet, B. Clement, S. Fischer, 1985, Molecular and Cellular Biochemistry.

The hepatocyte is a direct target for transforming-growth factor beta activation via the insulin-like growth factor II/mannose 6-phosphate receptor.

D. Gilot, C. Rescan, C. Guguen-Guillouzo, 2003, Journal of hepatology.

A plasma membrane protein is involved in cell contact-mediated regulation of tissue-specific genes in adult hepatocytes

C. Guguen-Guillouzo, D. Glaise, G. Baffet, 1991, The Journal of cell biology.

Growth control and cell cycle progression in cultured hepatocytes

C. Rescan, C. Guguen-Guillouzo, P. Loyer, 2000 .

The complexity of ERK1 and ERK2 MAPKs in multiple hepatocyte fate responses

G. Baffet, S. Langouët, N. Théret, 2012, Journal of cellular physiology.

The MAPK MEK1/2-ERK1/2 Pathway and Its Implication in Hepatocyte Cell Cycle Control

G. Baffet, C. Frémin, J. Guégan, 2012, International journal of hepatology.

RNAi‐mediated MEK1 knock‐down prevents ERK1/2 activation and abolishes human hepatocarcinoma growth in vitro and in vivo

G. Baffet, A. Bessard, S. Langouët, 2009, International journal of cancer.

Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42–Tuba pathway

Lisa Paysan, F. Saltel, V. Moreau, 2014, The Journal of cell biology.

Generation of proliferating human adult hepatocytes using optimized 3D culture conditions

G. Baffet, S. Langouët, V. Legagneux, 2021, Scientific reports.

Gene regulation by interleukin 6.

M. Hattori, G. Baffet, H. Baumann, 1991, Biochimie.

The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-β-Induced Epithelial to Mesenchymal Transition

R. Rimokh, G. Baffet, Laurent Fattet, 2015, PloS one.

Characterization of goldfish fin cells in culture: some evidence of an epithelial cell profile.

G. Baffet, C. Cauty, J. Bobe, 2009, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Integrative analysis of high-throughput RNAi screen data identifies the FER and CRKL tyrosine kinases as new regulators of the mitogenic ERK-dependent pathways in transformed cells

N. Le Meur, G. Baffet, S. Langouët, 2014, BMC Genomics.

Modifications of phosphoproteins and protein kinases occurring with in vitro aging of cultured human cells.

A. Guillouzo, G. Baffet, A. Kahn, 1982, Gerontology.

Involvement of the serine/threonine p70S6 kinase in TGF-beta1-induced ADAM12 expression in cultured human hepatic stellate cells.

G. Baffet, B. Clement, U. Wewer, 2005, Journal of hepatology.

Increasing 3D Matrix Rigidity Strengthens Proliferation and Spheroid Development of Human Liver Cells in a Constant Growth Factor Environment

G. Baffet, S. Langouët, N. Théret, 2016, Journal of cellular biochemistry.

Mechanism in the sequential control of cell morphology and S phase entry by epidermal growth factor involves distinct MEK/ERK activations.

C. Rescan, C. Guguen-Guillouzo, H. Talarmin, 2001, Molecular biology of the cell.

Distinct effects of cell-cell communication and corticosteroids on the synthesis and distribution of cytokeratins in cultured rat hepatocytes.

C. Guguen-Guillouzo, P. Loyer, D. Glaise, 1991, Journal of cell science.

DNA sequences homologous to mitochondrial genes in nuclei from normal rat tissues and from rat hepatoma cells.

A. Kitzis, C. Guguen-Guillouzo, G. Baffet, 1989, Biochemical and biophysical research communications.

Increased level of the mitochondrial ND5 transcript in chemically induced rat hepatomas.

C. Guguen-Guillouzo, G. Baffet, N. Defer, 1989, Experimental cell research.

Structure of a cDNA clone specific to hepatoma cells with rearranged mitochondrial sequences.

G. Baffet, N. Defer, M. Corral, 1988, Nucleic acids research.

Expression and activation of cdks (1 and 2) and cyclins in the cell cycle progression during liver regeneration.

L. Meijer, C. Guguen-Guillouzo, P. Loyer, 1994, The Journal of biological chemistry.

Growth Factor Dependence of Progression through G and S Phases of Adult Rat Hepatocytes in Vitro

C. Guguen-Guillouzo, M. Bilodeau, P. Loyer, 1996, The Journal of Biological Chemistry.

A role for caspase-8 and c-FLIPL in proliferation and cell-cycle progression of primary hepatocytes.

M. Peter, O. Fardel, D. Lagadic-Gossmann, 2005, Carcinogenesis.

The knock-down of ERCC1 but not of XPF causes multinucleation.

G. Baffet, S. Langouët, F. Ezan, 2011, DNA repair.

Transcriptional Control of Liver Acute Phase Genes by Interleukin-6 and Leukemia Inhibitory Factor

M. Hattori, G. Baffet, G. Hocke, 1991 .

DMSO-free highly differentiated HepaRG spheroids for chronic toxicity, liver functions and genotoxicity studies

G. Baffet, F. Nesslany, S. Langouët, 2021, Archives of Toxicology.

3D culture of HepaRG cells in GelMa and its application to bioprinting of a multicellular hepatic model.

J. Fricain, G. Baffet, S. Langouët, 2020, Biomaterials.

[1-9-NαC]-crourorb A1 isolated from Croton urucurana latex induces G2/M cell cycle arrest and apoptosis in human hepatocarcinoma cells.

G. Baffet, F. Ezan, M. D. F. Matos, 2017, Toxicology letters.

Protease profiling of liver fibrosis reveals the ADAM metallopeptidase with thrombospondin type 1 motif, 1 as a central activator of transforming growth factor beta

P. Tufféry, B. Mari, G. Baffet, 2011, Hepatology.

Transient expression of c-fos and constant expression of c-myc in freshly isolated and cultured normal adult rat hepatocytes.

C. Guguen-Guillouzo, D. Glaise, G. Baffet, 1988, Oncogene research.

The B[a]P-increased intercellular communication via translocation of connexin-43 into gap junctions reduces apoptosis.

M. Rissel, M. Dimanche-Boitrel, D. Lagadic-Gossmann, 2010, Toxicology and applied pharmacology.

The liver-specific response to phenobarbital involves a transient increase in phosphorylation of a 34-kda nuclear protein in rat liver and in hepatocytes in culture.

L. Corcos, G. Baffet, 1995, Biochemical and biophysical research communications.

A robust collagen scoring method for human liver fibrosis by second harmonic microscopy.

Christophe Odin, Bruno Turlin, Yann Le Grand, 2010, Optics express.

Integrative analysis of high-throughput RNAi screen data identifies the FER and CRKL tyrosine kinases as new regulators of the mitogenic ERK-dependent pathways in transformed cells

N. Le Meur, G. Baffet, S. Langouët, 2014, BMC Genomics.

Generation of proliferating human adult hepatocytes using optimized 3D culture conditions

G. Baffet, S. Langouët, V. Legagneux, 2021, Scientific Reports.

Linear least square (LLS) method for pixel-resolution analysis of polarization dependent SHG images of collagen fibrils.

J. Bellanger, G. Baffet, D. Rouède, 2015, Optics express.

Use of hepatocyte co-cultures in the assessment of drug toxicity from chronic exposure.

M. Rissel, A. Guillouzo, G. Baffet, 1988, Xenobiotica; the fate of foreign compounds in biological systems.

Introducing the scanning air puff tonometer for biological studies.

Olivier Sire, Vincent Fleury, Alia Al-Kilani, 2010, Physical review. E, Statistical, nonlinear, and soft matter physics.

Highly selective extraction of spiralin from the Spiroplasma citri cell membrane with alkyl-N-sulfobetaines.

G. Baffet, H. Wróblewski, A. Blanchard, 1985, Biochimie.

Hydrocortisone modulates the production of extracellular material and albumin in long-term cocultures of adult rat hepatocytes with other liver epithelial cells.

A. Guillouzo, C. Guguen-Guillouzo, D. Glaise, 1982, Biochemical and biophysical research communications.