D. Wiest

发表

Control of early thymocyte development by the pre-T cell receptor complex: A receptor without a ligand?

M. Carleton, D. Wiest, M. Berger, 1999, Seminars in immunology.

HEB is required for the specification of fetal IL-17-producing γδ T cells

D. Wiest, Michele K. Anderson, J. Zúñiga-Pflücker, 2017, Nature Communications.

Constitutive Notch signalling promotes CD4 CD8 thymocyte differentiation in the absence of the pre-TCR complex, by mimicking pre-TCR signals.

M. Carleton, M. Ciofani, D. Wiest, 2007, International immunology.

Disruption of Supv3L1 damages the skin and causes sarcopenia, loss of fat, and death

K. Boekelheide, J. Sedivy, D. Wiest, 2009, Mammalian Genome.

Incomplete endoplasmic reticulum (ER) retention in immature thymocytes as revealed by surface expression of "ER-resident" molecular chaperones.

A. Singer, G. Kreibich, A. Bhandoola, 1997, Proceedings of the National Academy of Sciences of the United States of America.

The molecular chaperone calnexin is expressed on the surface of immature thymocytes in association with clonotype‐independent CD3 complexes.

A. Singer, D. Wiest, W. Burgess, 1995, The EMBO journal.

Towards a molecular understanding of the differential signals regulating alphabeta/gammadelta T lineage choice.

D. Wiest, J. Stadanlick, Sang-Yun Lee, 2010, Seminars in immunology.

Recent insights into the signals that control αβ/γδ‐lineage fate

D. Wiest, M. Haks, Juliette M. Lefebvre, 2006 .

Early Growth Response Genes Regulate B Cell Development, Proliferation, and Immune Response1

A. Simmons, J. Monroe, D. Wiest, 2008, The Journal of Immunology.

A novel recurrent chromosomal inversion implicates the homeobox gene Dlx5 in T-cell lymphomas from Lck-Akt2 transgenic mice.

S. Jhanwar, J. Testa, A. Di Cristofano, 2008, Cancer research.

In vitro functional correction of the mutation responsible for murine severe combined immune deficiency by small fragment homologous replacement.

H. Zayed, D. Wiest, R. McIvor, 2005, Human gene therapy.

Appl1 and Appl2 are Expendable for Mouse Development But Are Essential for HGF‐Induced Akt Activation and Migration in Mouse Embryonic Fibroblasts

J. Testa, Yinfei Tan, D. Wiest, 2016, Journal of cellular physiology.

Appl1 is dispensable for Akt signaling in vivo and mouse T‐cell development

J. Testa, Yinfei Tan, D. Wiest, 2010, Genesis.

Stage-Specific and Differential Notch Dependency at the αβ and γδ T Lineage Bifurcation

M. Ciofani, D. Wiest, H. Boehmer, 2006 .

Disruption of Thrombocyte and T Lymphocyte Development by a Mutation in ARPC1B

I. Barshack, Yu Nee Lee, N. Amariglio, 2017, The Journal of Immunology.

Developmental regulation of αβ T cell antigen receptor assembly in immature CD4+CD8+ thymocytes

A. Singer, D. Wiest, K. Kearse, 1995 .

Developmental regulation of alpha beta T cell antigen receptor expression results from differential stability of nascent TCR alpha proteins within the endoplasmic reticulum of immature and mature T cells.

A. Singer, D. Wiest, T. Nakayama, 1994, The EMBO journal.

Regulation of lineage commitment distinct from positive selection.

D. Wiest, D. Allman, D. Kappes, 1999, Science.

Loss of Zfp335 triggers cGAS/STING-dependent apoptosis of post-β selection pre-T cells

Y. Zhuang, D. Wiest, A. Contreras, 2021, bioRxiv.

TCR activation of ZAP70 is impaired in CD4+CD8+ thymocytes as a consequence of intrathymic interactions that diminish available p56lck.

A. Singer, R. Abe, D. Wiest, 1996, Immunity.

Characterization of a Colony‐Stimulating Factor Produced by the Human Monocytic Leukemia Cell Line, THP‐1

M. Dell'aquila, D. Wiest, G. Huffnagle, 1986, Journal of leukocyte biology.

Egr2 Is Required for Bcl-2 Induction during Positive Selection1

D. Wiest, J. Alberola-Ila, S. Kurella, 2008, The Journal of Immunology.

Epitope Thy-1 / CD 90 Bearing the 6 C 10 Carbohydrate Recognized by Increased Expression of T Cell Maturation + Peripheral CD 4

R. Hardy, D. Wiest, K. Hayakawa, 1999 .

Peripheral CD4+ T cell maturation recognized by increased expression of Thy-1/CD90 bearing the 6C10 carbohydrate epitope.

R. Hardy, D. Wiest, K. Hayakawa, 1999, Journal of immunology.

Limiting TCR expression leads to quantitative but not qualitative changes in thymic selection.

D. Wiest, D. Allman, D. Kappes, 1999, Journal of immunology.

Thymic Selection Quantitative But Not Qualitative Changes in Limiting TCR Expression Leads to

D. Wiest, D. Allman, D. Kappes, 1999 .

Role of a selecting ligand in shaping the murine γδ-TCR repertoire

Roland L. Dunbrack, D. Wiest, L. Teyton, 2018, Proceedings of the National Academy of Sciences.

Riddle Wrapped in an Enigma T Cell Effector Subsets: A δ γ Origins of

D. Wiest, S. Fahl, Francis J. Coffey, 2014 .

Faculty Opinions recommendation of γδ TCR ligands: the quest to solve a 500-million-year-old mystery.

D. Wiest, A. Contreras, 2020 .

Expression of intracisternal A-type particles is increased when a B-cell lymphoma differentiates into an immunoglobulin-secreting cell

D. Wiest, Y. Argon, J. Burkhardt, 1989, Journal of virology.

Investigation of the causal etiology in a patient with T-B+NK+ immunodeficiency

Andrew G. Sharo, S. Brenner, W. Leonard, 2022, Frontiers in Immunology.

Low Activation Threshold As a Mechanism for Ligand-Independent Signaling in Pre-T Cells 1

M. Ciofani, D. Wiest, M. Haks, 2003, The Journal of Immunology.

T−B+NK+ severe combined immunodeficiency caused by complete deficiency of the CD3ζ subunit of the T-cell antigen receptor complex

M. Krangel, X. Zhong, D. Wiest, 2007 .

T-B+NK+ severe combined immunodeficiency caused by complete deficiency of the CD3zeta subunit of the T-cell antigen receptor complex.

M. Krangel, X. Zhong, D. Wiest, 2007, Blood.

severe combined immunodeficiency caused by complete deficiency of the CD 3 subunit of the T-cell antigen receptor complex

L. Staudt, A. Rosenwald, W. Chan, 2007 .

Severe Combined Immunodeficiency Caused by Complete Deficiency of the CD 3 ζ Subunit of the T Cell Antigen Receptor Complex Running Title : Human SCID Due to Complete CD 3 ζ Deficiency

M. Krangel, X. Zhong, D. Wiest, 2006 .

Developmentally regulated expression of CD3 components independent of clonotypic T cell antigen receptor complexes on immature thymocytes

A. Singer, D. Wiest, K. Kearse, 1994, The Journal of experimental medicine.

Noncanonical mode of ERK action controls alternative αβ and γδ T cell lineage fates.

M. Carleton, S. Hedrick, D. Wiest, 2014, Immunity.

Unequal Contribution of Akt Isoforms in the Double-Negative to Double-Positive Thymocyte Transition1

T. Ludwig, P. Tsichlis, D. Wiest, 2007, The Journal of Immunology.

Ablation of ribosomal protein L22 selectively impairs alphabeta T cell development by activation of a p53-dependent checkpoint.

S. Shinton, R. Hardy, S. Anderson, 2007, Immunity.

Stage-specific and differential notch dependency at the alphabeta and gammadelta T lineage bifurcation.

M. Ciofani, D. Wiest, H. von Boehmer, 2006, Immunity.

Competitive Displacement of pTα by TCR-α During TCR Assembly Prevents Surface Coexpression of Pre-TCR and αβ TCR1

D. Wiest, J. Zúñiga-Pflücker, P. Hugo, 2000, The Journal of Immunology.

Competitive Displacement of pTa by TCR-a During TCR Assembly Prevents Surface Coexpression of Pre-TCR and ab TCR

D. Wiest, J. Zúñiga-Pflücker, P. Hugo, 2000 .

Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent.

M. Ciofani, D. Wiest, J. Zúñiga-Pflücker, 2009, Immunity.

Branching out to gain control: how the pre-TCR is linked to multiple functions.

M. Carleton, D. Wiest, A. Kruisbeek, 2000, Immunology today.

Competitive displacement of pT alpha by TCR-alpha during TCR assembly prevents surface coexpression of pre-TCR and alpha beta TCR.

D. Wiest, J. Zúñiga-Pflücker, P. Hugo, 2000, Journal of immunology.

The connecting peptide domain of pTα dictates weak association of the pre‐T cell receptor with the TCR ζ subunit

D. Wiest, P. Hugo, A. Steff, 1999 .

The connecting peptide domain of pT alpha dictates weak association of the pre-T cell receptor with the TCR zeta subunit.

D. Wiest, P. Hugo, A. Steff, 1999, European journal of immunology.

Regulatory Roles of Rpl22 in Hematopoiesis: An Old Dog with New Tricks.

D. Wiest, Minshi Wang, S. Fahl, 2015, Critical reviews in immunology.

Subunit Composition of Pre–T Cell Receptor Complexes Expressed by Primary Thymocytes: CD3δ Is Physically Associated but Not Functionally Required

D. Wiest, M. Berger, G. Bosma, 1997, The Journal of experimental medicine.

The Ras/MAPK Pathway Is Required for Generation of iNKT Cells

D. Wiest, J. Alberola-Ila, Taishan Hu, 2011, PloS one.

Transcription factors NFAT2 and Egr1 cooperatively regulate the maturation of T-lymphoma in vitro

D. Wiest, E. Koltsova, T. Vavilova, 2007, Biochemistry (Moscow).

Mutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects

I. Barshack, E. Eyal, N. Amariglio, 2016, The Journal of experimental medicine.

Using the Zebrafish Model to Study T Cell Development.

D. Wiest, Yong Zhang, 2016, Methods in molecular biology.

Towards a molecular understanding of the differential signals regulating αβ / γδ T lineage choice

D. Wiest, J. Stadanlick, Sang-Yun Lee, 2010 .

Development of promyelocytic leukemia zinc finger-expressing innate CD4 T cells requires stronger T-cell receptor signals than conventional CD4 T cells

K. Hogquist, P. Lapinski, P. King, 2012, Proceedings of the National Academy of Sciences.

Altered functional responsiveness of thymocyte subsets from CD3delta-deficient mice to TCR-CD3 engagement.

B. Alarcón, D. Wiest, M. Berger, 1998, International immunology.

Altered functional responsiveness of thymocyte subsets from CD 3 δ-deficient mice to TCR – CD 3 engagement

B. Alarcón, D. Wiest, M. Berger, 1998 .

Pre-TCR-Induced β-Catenin Facilitates Traversal through β-Selection1

D. Wiest, Mai Xu, J. Sen, 2009, The Journal of Immunology.

Sustained Expression of Pre-TCR Induced β-Catenin in Post-β-Selection Thymocytes Blocks T Cell Development1

D. Wiest, Mai Xu, M. Hossain, 2009, The Journal of Immunology.

Faculty Opinions recommendation of Interleukin-17-Producing γδ T Cells Originate from SOX13+ Progenitors that Are Independent of γδTCR Signaling.

D. Wiest, A. Contreras, 2020, Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.

Attenuation of γδTCR Signaling Efficiently Diverts Thymocytes to the αβ Lineage

M. Carleton, D. Wiest, M. Haks, 2005 .

Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules

R. Klausner, L. Glimcher, A. Singer, 1993, The Journal of experimental medicine.

A Role for Ly108 in the Induction of Promyelocytic Zinc Finger Transcription Factor in Developing Thymocytes

E. Wakeland, J. Cannons, P. Schwartzberg, 2013, The Journal of Immunology.

Differential Roles of IL-2–Inducible T Cell Kinase-Mediated TCR Signals in Tissue-Specific Localization and Maintenance of Skin Intraepithelial T Cells

D. Wiest, A. August, Q. Qi, 2010, The Journal of Immunology.

Thymocyte Transition Double-Negative to Double-Positive Unequal Contribution of Akt Isoforms in the

T. Ludwig, P. Tsichlis, D. Wiest, 2007 .

Extracellular Signal–Regulated Kinase (Erk) Activation by the Pre-T Cell Receptor in Developing Thymocytes in Vivo

D. Wiest, A. Michie, J. Zúñiga-Pflücker, 1999, The Journal of experimental medicine.

Signals transduced by CD3epsilon, but not by surface pre-TCR complexes, are able to induce maturation of an early thymic lymphoma in vitro.

M. Carleton, D. Wiest, M. Berger, 1999, Journal of immunology.

Faculty Opinions recommendation of Shared dependence on the DNA-binding factor TOX for the development of lymphoid tissue-inducer cell and NK cell lineages.

D. Wiest, J. Perrigoue, 2010 .

Faculty Opinions recommendation of γδ T cells: pleiotropic immune effectors with therapeutic potential in cancer.

D. Wiest, A. Contreras, 2020 .

Enforcement of γδ-lineage commitment by the pre–T-cell receptor in precursors with weak γδ-TCR signals

D. Wiest, J. Zúñiga-Pflücker, Payam Zarin, 2014, Proceedings of the National Academy of Sciences.

Loss of Zfp335 triggers cGAS/STING-dependent apoptosis of post-β selection thymocytes

Y. Zhuang, D. Wiest, A. Contreras, 2022, Nature Communications.

Developmental Arrest of T Cells in Rpl22-Deficient Mice Is Dependent upon Multiple p53 Effectors

M. Carleton, S. Anderson, G. Zambetti, 2011, The Journal of Immunology.

Ribosomal Protein Rpl22 Controls the Dissemination of T-cell Lymphoma.

J. Testa, D. Wiest, Shuyun Rao, 2016, Cancer research.

Early growth response 1 and NF-ATc1 act in concert to promote thymocyte development beyond the beta-selection checkpoint.

M. Ciofani, R. Benezra, D. Wiest, 2007, Journal of immunology.

Early Growth Response Transcription Factors Are Required for Development of CD4−CD8− Thymocytes to the CD4+CD8+ Stage1

P. Linsley, M. Carleton, D. Wiest, 2002, The Journal of Immunology.

Early Growth Response Transcription Factors Are Required for Development of CD4 CD8 Thymocytes to the CD4 CD8 Stage

Allan Jones, M. Carleton, D. Wiest, 2002 .

This information is current as Tissue Localization T Cells for Specific Peripheral δγ Thymic Cutting Edge : Intrinsic Programming of and Na

Joonsoo Kang, D. Wiest, M. Xia, 2010 .

Tissue LocalizationT Cells for Specific Peripheral d g Thymic Cutting Edge: Intrinsic Programming of

Joonsoo Kang, D. Wiest, Natasha Narayan, 2022 .

Positive Selection Egr2 Is Required for Bcl-2 Induction during

D. Wiest, J. Alberola-Ila, S. Kurella, 2022 .

Factor in Developing Thymocytes Promyelocytic Zinc Finger Transcription A Role for Ly108 in the Induction of

E. Wakeland, J. Cannons, D. Wiest, 2013 .

TCR‐mediated ThPOK induction promotes development of mature (CD24−) γδ thymocytes

X. Hua, D. Wiest, H. Lee, 2010, The EMBO journal.

Attenuation of gammadeltaTCR signaling efficiently diverts thymocytes to the alphabeta lineage.

M. Carleton, D. Wiest, M. Haks, 2005, Immunity.

Transmembrane polar residues of TCR beta chain are required for signal transduction.

L. Spain, I. Tietjen, D. Wiest, 1998, International immunology.

Architectural Changes in the TCR:CD3 Complex Induced by MHC:Peptide Ligation1

N. L. La Gruta, D. Wiest, D. Vignali, 2004, The Journal of Immunology.

Complex Induced by MHC:Peptide Ligation Architectural Changes in the TCR:CD3

N. Gruta, D. Wiest, D. Vignali, 2004 .

Developmental regulation of alpha beta T cell antigen receptor assembly in immature CD4+CD8+ thymocytes.

A. Singer, D. Wiest, K. Kearse, 1995, BioEssays : news and reviews in molecular, cellular and developmental biology.

Functional Genomic Landscape of Acute Myeloid Leukemia

Beth Wilmot, Erik Segerdell, Shannon K. McWeeney, 2018, Nature.

Noncanonical Mode of ERK Action Controls Alternative ab and gd T Cell Lineage Fates

M. Carleton, S. Hedrick, D. Wiest, 2014 .

Non-canonical mode of ERK action controls alternative αβ and γδ T lineage fates

M. Carleton, S. Hedrick, D. Wiest, 2014 .

γδ T cells get adaptive

D. Wiest, J. Strid, B. Silva-Santos, 2017, Nature Immunology.

A Novel Mechanism for B Cell Repertoire Maturation Based on Response by B Cell Precursors to Pre–B Receptor Assembly

T. Manser, S. Shinton, R. Hardy, 1998, The Journal of experimental medicine.

Subcellular localization of T-cell receptor complexes containing tyrosine-phosphorylated zeta proteins in immature CD4+CD8+ thymocytes.

A. Singer, D. Wiest, K. Kearse, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate

Aaron N. Chang, C. Murre, D. Wiest, 2017, Cell.

Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing.

B. Kennedy, S. Melov, D. Morris, 2017, Cell reports.

Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B.

A. Look, J. Testa, Rugang Zhang, 2012, Blood.

The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin.

Y. Wang, B. Karlan, J. Benítez, 2016, Cancer research.

The homeoprotein Dlx5 drives murine T-cell lymphomagenesis by directly transactivating Notch and upregulating Akt signaling

J. Testa, Yinfei Tan, Jinfei Xu, 2017, Oncotarget.

Mechanistic basis of pre–T cell receptor–mediated autonomous signaling critical for thymocyte development

M. Tokunaga, K. Sakata-Sogawa, D. Wiest, 2006, Nature Immunology.

The Ribosomal Protein Rpl22 Controls Ribosome Composition by Directly Repressing Expression of Its Own Paralog, Rpl22l1

Katherine H. Schreiber, B. Kennedy, P. Fink, 2013, PLoS genetics.

JUN is a key transcriptional regulator of the unfolded protein response in acute myeloid leukemia

S Balachandran, S. Fröhling, C. Scholl, 2017, Leukemia.

Control of hematopoietic stem cell emergence by antagonistic functions of ribosomal protein paralogs.

D. Wiest, Shuyun Rao, Qin Li, 2013, Developmental cell.

Fli‐1 regulates the DN2 to DN3 thymocyte transition and promotes γδ T‐cell commitment by enhancing TCR signal strength

D. Wiest, D. Izon, M. Smeets, 2014, European journal of immunology.

HEB is required for the specification of fetal IL-17-producing γδ T cells

D. Wiest, Michele K. Anderson, J. Zúñiga-Pflücker, 2017, Nature Communications.

Recurrent chromosomal rearrangements implicate oncogenes contributing to T‐cell lymphomagenesis in Lck‐MyrAkt2 transgenic mice

J. Testa, Yinfei Tan, D. Wiest, 2009, Genes, chromosomes & cancer.

Membrane biogenesis during B cell differentiation: most endoplasmic reticulum proteins are expressed coordinately

D. Wiest, D. Meyer, M. Hortsch, 1990, The Journal of cell biology.

Transmembrane polar residues of TCR β chain are required for signal transduction

I. Tietjen, D. Wiest, S. Fuller-Espie, 1998 .

Functional genomic landscape of acute myeloid leukaemia

R. Collins, D. Bottomly, S. McWeeney, 2018, Nature.

Rpl22 Loss Selectively Impairs αβ T Cell Development by Dysregulating Endoplasmic Reticulum Stress Signaling

D. Wiest, Nehal R Solanki, J. Stadanlick, 2016, The Journal of Immunology.

This information is current as Reticulum Stress Signaling Development by Dysregulating Endoplasmic T Cell βα Rpl 22 Loss Selectively Impairs

D. Wiest, Nehal R Solanki, J. Stadanlick, 2016 .

Ablation of Ribosomal Protein L22 Selectively Impairs αβ T Cell Development by Activation of a p53-Dependent Checkpoint

S. Shinton, R. Hardy, S. Anderson, 2007 .

NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma

Yi Zhao, Jian Hu, David C. Corney, 2020, Cell reports.

Early Growth Response 1 and NF-ATc1 Act in Concert to Promote Thymocyte Development beyond the β-Selection Checkpoint1

M. Ciofani, R. Benezra, D. Wiest, 2007, The Journal of Immunology.

Checkpoint-Selection β Development beyond the in Concert to Promote Thymocyte Early Growth Response 1 and NF-ATc 1 Act

M. Ciofani, R. Benezra, D. Wiest, 2007 .

Enforced Expression of Spi-B Reverses T Lineage Commitment and Blocks β-Selection 1

M. Carleton, L. Eisenlohr, L. Garrett-Sinha, 2005, The Journal of Immunology.

Subversion of T lineage commitment by PU.1 in a clonal cell line system.

Kevin Y. Tse, D. Wiest, E. Rothenberg, 2005, Developmental biology.

Activation-induced ubiquitination of the T cell antigen receptor.

V. Fried, B. Rellahan, A. Weissman, 1992, Science.

A Correction to the Protocol Titled "High-Sensitivity Detection and Quantitative Analysis of Native Protein-Protein Interactions and Multiprotein Complexes by Flow Cytometry" by A. G. Schrum et al.

E. Palmer, W. Schamel, L. Turka, 2007, Science's STKE.

High-Sensitivity Detection and Quantitative Analysis of Native Protein-Protein Interactions and Multiprotein Complexes by Flow Cytometry

E. Palmer, W. Schamel, L. Turka, 2007, Science's STKE.

The expression of membrane and secreted immunoglobulin during the in vitro differentiation of the murine B cell lymphoma CH12.

D. Wiest, M. Digel, Y. Argon, 1987, Journal of immunology.

Recent insights into PERK-dependent signaling from the stressed endoplasmic reticulum

D. Wiest, 2019 .

induction of the stemness factor, Lin28B Inactivation of ribosomal protein L22 promotes transformation by

J. Testa, Rugang Zhang, S. Hunger, 2012 .

Kri1l: a novel gene that links defective ribosome biogenesis to impaired hematopoiesis through excessive autophagy

D. Wiest, Yong Zhang, Yong Zhang, 2015 .

Rpl22 Loss Impairs the Development of B Lymphocytes by Activating a p53-Dependent Checkpoint

D. Wiest, Francis J. Coffey, Shawn P. Fahl, 2015, The Journal of Immunology.

CD45-deficient severe combined immunodeficiency caused by uniparental disomy

Roland L. Dunbrack, J. Testa, X. Zhong, 2012, Proceedings of the National Academy of Sciences.

A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development.

D. Singer, A. Singer, R. Abe, 1997, Immunity.

Correction of DNA protein kinase deficiency by spliceosome-mediated RNA trans-splicing and sleeping beauty transposon delivery.

M. Kay, J. Tolar, H. Zayed, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

RPL22L1 induction in colorectal cancer is associated with poor prognosis and 5-FU resistance

J. Testa, J. Hoffmann, D. Wiest, 2019, PloS one.

A Novel Germline Heterozygous BCL11B Variant Causing Severe Atopic Disease and Immune Dysregulation

M. Messing, A. Lehman, J. Milner, 2021, Frontiers in Immunology.

Multisystem Anomalies in Severe Combined Immunodeficiency with Mutant BCL11B.

Aashish N. Adhikari, R. Srinivasan, S. Brenner, 2016, The New England journal of medicine.

Redundant Role for Early Growth Response Transcriptional Regulators in Thymocyte Differentiation and Survival1

W. Tourtellotte, D. Wiest, J. Carter, 2007, The Journal of Immunology.

Tcra Enhancer Activation by Inducible Transcription Factors Downstream of Pre-TCR Signaling

D. Wiest, C. Hernández-Munain, B. del Blanco, 2012, The Journal of Immunology.

Pre-TCR Signaling Transcription Factors Downstream of Enhancer Activation by Inducible Tcra

D. Wiest, C. Hernández-Munain, A. García-Mariscal, 2012 .

The TCR ligand-inducible expression of CD73 marks γδ lineage commitment and a metastable intermediate in effector specification

D. Wiest, L. Thompson, J. Zúñiga-Pflücker, 2014, The Journal of experimental medicine.

On the dynamics of TCR:CD3 complex cell surface expression and downmodulation.

D. Wiest, D. Vignali, H. Liu, 2000, Immunity.

Interleukin-27 signaling serves as an immunological checkpoint for innate cytotoxic cells to promote hepatocellular carcinoma.

X. Wang, A. Dzutsev, G. Trinchieri, 2022, Cancer discovery.

ZAP-70 Protein Promotes Tyrosine Phosphorylation of T Cell Receptor Signaling Motifs (ITAMs) in Immature CD4+8+ Thymocytes with Limiting p56lck

A. Singer, R. Abe, D. Wiest, 1999, The Journal of experimental medicine.

Pre-TCR-induced beta-catenin facilitates traversal through beta-selection.

D. Wiest, Mai Xu, J. Sen, 2009, Journal of immunology.

Origins of γδ T Cell Effector Subsets: A Riddle Wrapped in an Enigma

D. Wiest, Francis J. Coffey, Shawn P. Fahl, 2014, The Journal of Immunology.

Cutting Edge: Intrinsic Programming of Thymic γδT Cells for Specific Peripheral Tissue Localization

Joonsoo Kang, D. Wiest, Yanming Wang, 2010, The Journal of Immunology.

Recent advances in understanding the development and function of γδ T cells

D. Wiest, A. Contreras, 2020, F1000Research.

The E protein-TCF1 axis controls γδ T cell development and effector fate

C. Murre, D. Wiest, A. Contreras, 2021, Cell reports.

Loss of Ribosomal Protein Paralog Rpl22-like1 Blocks Lymphoid Development without Affecting Protein Synthesis

D. Wiest, A. Contreras, J. Perrigoue, 2022, The Journal of Immunology.

Identification of a novel pre-TCR isoform in which the accessibility of the TCRβ subunit is determined by occupancy of the 'missing' V domain of pre-Tα

Roland L. Dunbrack, J. M. Sauder, M. Carleton, 2000 .

Structurally distinct T cell receptor complexes on developmentally distinct T cell populations in severe combined immunodeficiency mice expressing a TCR beta transgene.

A. Singer, Y. Takahama, D. Wiest, 1993, Journal of immunology.

Decreased signaling competence as a result of receptor overexpression: overexpression of CD4 reduces its ability to activate p56lck tyrosine kinase and to regulate T-cell antigen receptor expression in immature CD4+CD8+ thymocytes.

K. M. Abraham, R. Perlmutter, A. Singer, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Id3 Restricts γδ NKT Cell Expansion by Controlling Egr2 and c-Myc Activity

Y. Zhuang, D. Wiest, Baojun Zhang, 2018, The Journal of Immunology.

Ontogenic timing, T cell receptor signal strength, and Notch signaling direct γδ T cell functional differentiation in vivo

Christina R. Lee, D. Wiest, Michele K. Anderson, 2021, Cell reports.

The Role of MAPKs in B Cell Receptor-induced Down-regulation of Egr-1 in Immature B Lymphoma Cells*

A. Simmons, J. Monroe, D. Wiest, 2006, Journal of Biological Chemistry.

Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish

D. Balciunas, S. Shinton, R. Hardy, 2015, PloS one.

Faculty Opinions recommendation of Commensal microbiota promote lung cancer development via γδ T cells.

D. Wiest, A. Contreras, 2020 .

Control of Early T Cell Development by Notch and T Cell Receptor Signals

D. Wiest, Francis J. Coffey, D. MacCormack, 2016 .

Integration of T‐cell receptor, Notch and cytokine signals programs mouse γδ T‐cell effector differentiation

D. Wiest, Michele K. Anderson, J. Zúñiga-Pflücker, 2018, Immunology and cell biology.

Development of γδ T Cells, the Special-Force Soldiers of the Immune System.

D. Wiest, 2016, Methods in molecular biology.

Ribosomal protein control of hematopoietic stem cell transformation through direct, non-canonical regulation of metabolism

K. Pradhan, Amit Verma, S. Sykes, 2023, bioRxiv.

Identification of the Last Cog in a Ligand-Independent Signaling Machine?

D. Wiest, 2009, The Journal of Immunology.

Recent insights into the signals that control alphabeta/gammadelta-lineage fate.

D. Wiest, M. Haks, Juliette M. Lefebvre, 2006, Immunological reviews.

TCR Signaling Circuits in αβ/γδ T Lineage Choice

D. Wiest, D. Kappes, Shawn P. Fahl, 2018 .

Transcription factor EGR2 controls homing and pathogenicity of T_H17 cells in the central nervous system

Y. Belkaid, W. Leonard, J. O’Shea, 2023, Nature Immunology.

A Novel Mechanism for B Cell Repertoire Maturation Based on Response by B Cell Precursors to Pre–B Receptor Assembly

T. Manser, S. Shinton, R. Hardy, 1998, The Journal of experimental medicine.

Edinburgh Research Explorer The BRCA1-11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin.

B. Karlan, J. Benítez, P. Pharoah, 2018 .