C. Basbaum

发表

Tumor‐derived EMMPRIN (extracellular matrix metalloproteinase inducer) stimulates collagenase transcription through MAPK p38

Jian-Dong Li, B. Toole, M. Lim, 1998, FEBS letters.

Phorbol 12-Myristate 13-Acetate Up-regulates the Transcription of MUC2 Intestinal Mucin via Ras, ERK, and NF-κB*

Y. S. Kim, Jian-Dong Li, C. Basbaum, 2002, The Journal of Biological Chemistry.

The serous cell.

C. Basbaum, W. Finkbeiner, B. Jany, 1990, Annual review of physiology.

Concurrent increases in the storage and release of mucin-like molecules by rat airway epithelial cells in response to bacterial endotoxin.

C. Basbaum, J. Harkema, J. Hotchkiss, 1995, American journal of respiratory cell and molecular biology.

Quantitative fluorescence measurement of chloride transport mechanisms in phospholipid vesicles.

A. Verkman, C. Basbaum, R. Takla, 1989, Biochemistry.

Activation of NF-kappaB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells.

Jian-Dong Li, Y. Kim, M. Gallup, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Localization of Na pumps in the tracheal epithelium of the dog

C. Basbaum, J. Widdicombe, J. Y. Yee, 1979, The Journal of cell biology.

Stable differentiation of a human colon adenocarcinoma cell line by sodium butyrate is associated with multidrug resistance

B. Neuschwander‐Tetri, R. Dahiya, Y. Kim, 1994, Journal of cellular physiology.

Mapping of adrenergic receptors in the trachea by autoradiography.

P. Barnes, C. Basbaum, 1983, Experimental lung research.

Immune Complex-Dependent Remodeling of the Airway Vasculature in Response to a Chronic Bacterial Infection1

D. McDonald, N. Killeen, C. Basbaum, 2005, The Journal of Immunology.

Tobacco Smoke-induced Lung Cell Proliferation Mediated by Tumor Necrosis Factor α-converting Enzyme and Amphiregulin*

M. Gallup, C. Basbaum, S. Sidhu, 2003, Journal of Biological Chemistry.

Detection of occult tumor cells in lymph nodes from bladder cancer patients by MUC7 nested RT-PCR.

M. Stöckle, H. Kalthoff, C. Basbaum, 2004, European urology.

Adenosine up‐regulation of the mucin gene, MU2, in asthma

M. Gallup, N. McNamara, I. Maltseva, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A morphometric analysis of the autonomic innervation of cat tracheal glands.

J. Nadel, C. Basbaum, C. Murlas, 1980, Journal of the autonomic nervous system.

Altered mucin expression is a field change that accompanies mucinous (colloid) breast carcinoma histogenesis.

Z. Shao, S. Barsky, Z. Shao, 1998, Human pathology.

Wnt and Hedgehog Are Critical Mediators of Cigarette Smoke-Induced Lung Cancer

M. Gallup, C. Basbaum, S. Sidhu, 2006, PloS one.

Tobacco Smoke Control of Mucin Production in Lung Cells Requires Oxygen Radicals AP-1 and JNK*

M. Gallup, C. Basbaum, E. Gensch, 2004, Journal of Biological Chemistry.

Persistent mucin glycoprotein alterations in equine recurrent airway obstruction.

C. Basbaum, J. Harkema, N. E. Robinson, 2001, American journal of physiology. Lung cellular and molecular physiology.

Allergen-induced IL-9 directly stimulates mucin transcription in respiratory epithelial cells.

S. Wenzel, M. Gallup, C. Basbaum, 1999, The Journal of clinical investigation.

Signaling networks controlling mucin production in response to Gram-positive and Gram-negative bacteria

N. McNamara, C. Basbaum, 2001, Glycoconjugate Journal.

Localization of mucin (MUC2 and MUC3) messenger RNA and peptide expression in human normal intestine and colon cancer.

Y. Kim, C. Basbaum, J. Gum, 1994, Gastroenterology.

Squamous Transformation of Corneal Epithelial Cells is Stimulated by Inflammatory Mediators.

S. Reddy, N. McNamara, C. Basbaum, 2004 .

Chairman's Summary

C. Basbaum, 1991 .

Markers of mucus secretion and DNA levels in induced sputum from asthmatic and from healthy subjects.

H. Boushey, C. Basbaum, J. Fahy, 1993, The American review of respiratory disease.

A novel role for murine IL-4 in vivo: induction of MUC5AC gene expression and mucin hypersecretion.

R. Flavell, M. Gallup, C. Basbaum, 1997, American journal of respiratory cell and molecular biology.

Mucin gene (MUC 2 and MUC 5AC) upregulation by Gram-positive and Gram-negative bacteria.

Jian-Dong Li, J. Nadel, M. Gallup, 1998, Biochimica et biophysica acta.

Characterization of beta-adrenergic receptors in cultured bovine tracheal gland cells.

C. Basbaum, W. Finkbeiner, J. Madison, 1989, The American journal of physiology.

Long-lasting effects of chronic ozone exposure on rat nasal epithelium.

M. Gallup, C. Basbaum, E. Barr, 1999, American journal of respiratory cell and molecular biology.

Novel Cytoplasmic Proteins of Nontypeable Haemophilus influenzae Up-regulate Human MUC5AC Mucin Transcription via a Positive p38 Mitogen-activated Protein Kinase Pathway and a Negative Phosphoinositide 3-Kinase-Akt Pathway*

Jiahuai Han, Jian-Dong Li, C. Basbaum, 2002, The Journal of Biological Chemistry.

Leukotriene D4 Upregulates MUC2 Gene Transcription in Human Epithelial Cells

H. Ishinaga, C. Basbaum, K. Takeuchi, 2008, Pharmacology.

Localization of Mucin (MUCZ and MUC3) and Peptide Expression in Human Normal Cancer Messenger RNA Intestine and Colon

C. Basbaum, J. Gum, Y. S. Kim, 1994 .

Muscarinic receptors: evidence for a nonuniform distribution in tracheal smooth muscle and exocrine glands

C. Basbaum, J. Widdicombe, M. Grillo, 1984, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Characterization of human tracheal epithelial cells transformed by an origin-defective simian virus 40.

M. Welsh, J. Nadel, C. Basbaum, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease.

J. D. Li, Y. Kim, J. Nadel, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Human bronchus and intestine express the same mucin gene.

Y. Kim, M. Gallup, C. Basbaum, 1991, The Journal of clinical investigation.

Cloning of the Amino-terminal and 5′-Flanking Region of the HumanMUC5AC Mucin Gene and Transcriptional Up-regulation by Bacterial Exoproducts*

M. Gallup, C. Basbaum, N. Fan, 1998, The Journal of Biological Chemistry.

Enkephalinase inhibitor potentiates mammalian tachykinin-induced contraction in ferret trachea.

J. Nadel, C. Basbaum, K. Sekizawa, 1987, The Journal of pharmacology and experimental therapeutics.

Use of mucin antibodies and cDNA probes to quantify hypersecretion in vivo in human airways.

H. Boushey, C. Basbaum, J. Fahy, 1994, American journal of respiratory cell and molecular biology.

Mast cell chymase. A potent secretagogue for airway gland serous cells.

J. Nadel, C. Basbaum, S. Lazarus, 1989, Journal of immunology.

Autoradiographic localization of autonomic receptors in airway smooth muscle. Marked differences between large and small airways.

P. Barnes, J. Nadel, C. Basbaum, 1983, The American review of respiratory disease.

Muscarinic receptors in lung and trachea: autoradiographic localization using [3H]quinuclidinyl benzilate.

P. Barnes, J. Nadel, J. Roberts, 1982, European journal of pharmacology.

Establishment and characterization of a cell line derived from bovine tracheal glands

J. Nadel, C. Basbaum, W. Finkbeiner, 1986, In Vitro Cellular & Developmental Biology.

Receptors on airway gland cells.

C. Basbaum, W. Finkbeiner, J. Madison, 1990, The American review of respiratory disease.

Nontypeable Haemophilus influenzae lipoprotein P6 induces MUC5AC mucin transcription via TLR2-TAK1-dependent p38 MAPK-AP1 and IKKβ- IκBα-NF-κB signaling pathways

Jian-Dong Li, H. Jono, J. Lim, 2004 .

Localization of beta-adrenoreceptors in mammalian lung by light microscopic autoradiography.

P. Barnes, J. Nadel, C. Basbaum, 1982, Nature.

Pulmonary α-adrenoceptors: Autoradiographic localization using [3H]prazosin

P. Barnes, J. Nadel, C. Basbaum, 1983 .

cAMP immunocytochemistry provides evidence for functional VIP receptors in trachea.

P. Barnes, C. Basbaum, S. Lazarus, 1986, The American journal of physiology.

Neuropeptides degranulate serous cells of ferret tracheal glands.

J. Nadel, C. Basbaum, W. Finkbeiner, 1986, The American journal of physiology.

Innervation of the Airway Mucosa and Submucosa

C. Basbaum, 1984 .

Adrenergic and cholinergic receptors in submucosal glands of the ferret trachea: autoradiographic localization.

P. Barnes, J. Nadel, C. Basbaum, 1983, European journal of respiratory diseases. Supplement.

Modification of mucin gene expression in the airways of rats exposed to sulfur dioxide.

Y. Kim, M. Gallup, C. Basbaum, 1990, Biorheology.

Chronic Bacterial Infection the Airway Vasculature in Response to a Immune Complex-Dependent Remodeling of McDonald and Nigel

D. McDonald, N. Killeen, C. Basbaum, 2005 .

The architecture of nerves and ganglia of the ferret trachea as revealed by acetylcholinesterase histochemistry

D. McDonald, C. Basbaum, R. Mitchell, 1986, The Journal of comparative neurology.

In vivo activity of tracheal parasympathetic ganglion cells innervating tracheal smooth muscle

C. Basbaum, R. Mitchell, D. G. Baker, 1987, Brain Research.

Dog tracheal epithelial cells in culture synthesize sulfated macromolecular glycoconjugates and release them from the cell surface upon exposure to extracellular proteinases.

J. Nadel, C. Basbaum, L. S. Forsberg, 1987, Experimental lung research.

Long-term culture of normal and cystic fibrosis epithelial cells grown under serum-free conditions

C. Basbaum, J. Widdicombe, D. Gruenert, 1990, In Vitro Cellular & Developmental Biology.

Structural changes associated with fluid absorption by dog tracheal epithelium.

C. Basbaum, J. Widdicombe, I. Nathanson, 1986, Experimental lung research.

Mechanisms by which gram-positive bacteria and tobacco smoke stimulate mucin induction through the epidermal growth factor receptor (EGFR).

M. Gallup, C. Basbaum, E. Gensch, 2002, Novartis Foundation symposium.

Localization and release of lysozyme from ferret trachea: Effects of adrenergic and cholinergic drugs

J. Nadel, C. Basbaum, M. Tom-Moy, 2004, Cell and Tissue Research.

Neutrophil elastase and cathepsin G stimulate secretion from cultured bovine airway gland serous cells.

George, J. Nadel, C. Basbaum, 1990, The Journal of clinical investigation.

Bovine tracheal serous cell secretion: role of cAMP and cAMP-dependent protein kinase.

C. Basbaum, J. Widdicombe, W. Finkbeiner, 1992, The American journal of physiology.

Glycoconjugates secreted by bovine tracheal serous cells in culture.

C. Basbaum, W. Finkbeiner, J. Picard, 1988, Archives of biochemistry and biophysics.

Studies of tracheal secretion using serous cell cultures and monoclonal antibodies.

A. Paul, C. Basbaum, W. Finkbeiner, 1987, Biorheology.

Sp1 is involved in the transcriptional activation of lysozyme in epithelial cells.

M. Suico, T. Shuto, Tomoaki Koga, 2004, Biochemical and biophysical research communications.

Degradation of extracellular matrix by the trophoblastic cells of first‐trimester human placentas

R. Kramer, S. Fisher, C. Basbaum, 1985, Journal of cellular biochemistry.

Upregulation of the 72-kDa type IV collagenase in epithelial and stromal cells during rat tracheal gland morphogenesis.

M. Lim, C. Basbaum, A. Dohrman, 1995, Developmental biology.

Monoclonal Antibodies Directed Against Human Airway Secretions

C. Basbaum, W. Finkbeiner, 2007 .

Monoclonal antibodies directed against human airway secretions. Localization and characterization of antigens.

C. Basbaum, W. Finkbeiner, 1988, The American journal of pathology.

Myeloid ELF-1-like Factor Up-regulates Lysozyme Transcription in Epithelial Cells*

C. Basbaum, T. Miyata, A. Hisatsune, 1999, The Journal of Biological Chemistry.

Molecular cloning of the amino-terminal region of a rat MUC 2 mucin gene homologue. Evidence for expression in both intestine and airway.

Y. Kim, M. Gallup, C. Basbaum, 1994, The Journal of biological chemistry.

Sodium-pump density of cells from dog tracheal mucosa.

C. Basbaum, J. Widdicombe, E. Highland, 1985, The American journal of physiology.

AsialoGM1 and TLR5 cooperate in flagellin-induced nucleotide signaling to activate Erk1/2.

D. McKemy, M. Gallup, N. McNamara, 2006, American journal of respiratory cell and molecular biology.

Transcriptional regulation of the lysozyme gene in airway gland serous cells

Jian-Dong Li, H. Kai, K. Takeuchi, 1996, Journal of cellular biochemistry.

Extracellular matrix proteins regulate morphologic and biochemical properties of tracheal gland serous cells through integrins.

J. Tournier, C. Damsky, C. Basbaum, 1992, American journal of respiratory cell and molecular biology.

Ion contents and other properties of isolated cells from dog tracheal epithelium.

C. Basbaum, J. Widdicombe, E. Highland, 1981, The American journal of physiology.

Tracheal gland mucous cells stimulated in vitro with adrenergic and cholinergic drugs.

J. Nadel, C. Basbaum, A. Gashi, 1989, Tissue & cell.

Regulation of secretion from serous and mucous cells in the trachea.

C. Basbaum, 2008, Ciba Foundation symposium.

Localization of cAMP in dog and cat trachea: effects of beta-adrenergic agonists.

C. Basbaum, S. Lazarus, W. Gold, 1984, American Journal of Physiology.

Nontypeable Haemophilus influenzae lipoprotein P6 induces MUC5AC mucin transcription via TLR2-TAK1-dependent p38 MAPK-AP1 and IKKbeta-IkappaBalpha-NF-kappaB signaling pathways.

Jian-Dong Li, H. Jono, J. Lim, 2004, Biochemical and biophysical research communications.

Inhibition of mucin glycosylation by aryl-N-acetyl-alpha-galactosaminides in human colon cancer cells.

Y. Kim, C. Basbaum, J. Byrd, 1989, The Journal of biological chemistry.

Effects of magnesium ions on adrenergic nerve terminals

C. Basbaum, 1974, Journal of neurocytology.

Morphological studies of stimulated adrenergic axon varicosities in the mouse vas deferens

C. Basbaum, J. Heuser, 1979, The Journal of cell biology.

Exposure of human corneal epithelial cells to contact lenses in vitro suppresses the upregulation of human beta-defensin-2 in response to antigens of Pseudomonas aeruginosa.

N. McNamara, I. Maltseva, S. Fleiszig, 2007, Experimental eye research.

Identification of erythrocyte Gal alpha 1-3Gal glycosphingolipids with a mouse monoclonal antibody, Gal-13.

C. Basbaum, S. Shohet, U. Galili, 1987, The Journal of biological chemistry.

Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells

C. Basbaum, H. Lemjabbar, Hassan Lemjabbar, 2002, Nature Medicine.

Treatment of Cancer

E. Kun, C. Basbaum, V. Ossovskaya, 1998 .

Focalized proteolysis: spatial and temporal regulation of extracellular matrix degradation at the cell surface.

Z. Werb, C. Basbaum, 1996, Current opinion in cell biology.

Regulation of mucin gene expression in human tracheobronchial epithelial cells by thyroid hormone.

J. Koo, C. Basbaum, T. Gray, 2001, The Biochemical journal.

Plasticity in the airway epithelium.

C. Basbaum, B. Jany, 1990, The American journal of physiology.

A transformed human epithelial cell line that retains tight junctions post crisis

L. Chin, D. Friend, G. Cutting, 1992, In Vitro Cellular & Developmental Biology - Animal.

TACE/ADAM-17 Phosphorylation by PKC-Epsilon Mediates Premalignant Changes in Tobacco Smoke-Exposed Lung Cells

M. Gallup, C. Basbaum, S. Sidhu, 2011, PloS one.

CXCR4 expression reflects tumor progression and regulates motility of bladder cancer cells

P. Carroll, F. Waldman, C. Basbaum, 2005, International journal of cancer.

Transmission in airway ganglia of ferrets: Inhibition by norepinephrine

C. Basbaum, R. Mitchell, D. G. Baker, 1983, Neuroscience Letters.

ATP transduces signals from ASGM1, a glycolipid that functions as a bacterial receptor

David Julius, D. McKemy, D. Julius, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Induced hypothermia in peripheral nerve: Electron microscopic and electrophysiological observations

C. Basbaum, 1973, Journal of neurocytology.

The transcriptional responses of respiratory epithelial cells to Bordetella pertussis reveal host defensive and pathogen counter-defensive strategies.

T. Gingeras, J. Drenkow, D. Relman, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Sp1 protein contributes to airway-specific rat MUC 2 mucin gene transcription.

Y. Kim, M. Gallup, J. D. Li, 1997, Gene.

Pranlukast Inhibits NF-κB Activation and MUC2 Gene Expression in Cultured Human Epithelial Cells

Kazuhiko Takeuchi, H. Ishinaga, C. Basbaum, 2005, Pharmacology.

Characterization of quantitative mucin variants from a human colon cancer cell line.

Y. Kim, C. Basbaum, J. Byrd, 1987, Cancer research.

Control of mucin transcription by diverse injury-induced signaling pathways.

N. McNamara, C. Basbaum, E. Gensch, 1999, American journal of respiratory and critical care medicine.

Mechanism by which bacterial flagellin stimulates host mucin production.

N. McNamara, C. Basbaum, 2002, Advances in Experimental Medicine and Biology.

Mucin in disease. Modification of mucin gene expression in airway disease.

C. Basbaum, B. Jany, 1991, The American review of respiratory disease.

Roxithromycin Suppresses Mucin Gene Expression in Epithelial Cells

H. Ishinaga, C. Basbaum, K. Takeuchi, 2004, Pharmacology.

EMMPRIN regulates the canonical Wnt/β-catenin signaling pathway, a potential role in accelerating lung tumorigenesis

C. Basbaum, R. Nawroth, M. Retz, 2010, Oncogene.

Viral dsRNA activates mucin transcription in airway epithelial cells

N. McNamara, C. Basbaum, V. Londhe, 2003, FEBS letters.

Excitatory and inhibitory processes in hypothalamic conditioning in cats: role of the history of the negative stimulus.

C. Basbaum, E. Thomas, 1972, Journal of comparative and physiological psychology.

Distribution of lysozyme and mucin (MUC2 and MUC3) mRNA in human bronchus.

M. Cardone, Y. Kim, C. Basbaum, 1994, Experimental lung research.

Cigarette smoke disrupts the integrity of airway adherens junctions through the aberrant interaction of p120‐catenin with the cytoplasmic tail of MUC1

M. Gallup, N. McNamara, C. Basbaum, 2013, The Journal of pathology.

The microvesicle as a vehicle for EMMPRIN in tumor–stromal interactions

J. Lavail, C. Basbaum, S. Sidhu, 2004, Oncogene.

Lysozyme and Mucin cDNAs as Tools for the Study of Serous and Mucous Cell Differentiation

C. Basbaum, B. Jany, K. Takeuchi, 1992, Chest.

Synthesis and secretion of an albumin-like protein by cultured bovine tracheal gland serous cells.

C. Basbaum, C. Sommerhoff, J. Jacquot, 1988, Biochemical and biophysical research communications.

Expression of gelatinase A, a mediator of extracellular matrix remodeling, by tracheal gland serous cells in culture and in vivo.

Z. Werb, M. Polette, J. Tournier, 1994, The Journal of biological chemistry.

Airway Secretion: A Cell-Specific Analysis

C. Basbaum, W. Finkbeiner, 1988, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Toxicity of Chemical Components of Fine Particles Inhaled by Aged Rats: Effects of Concentration

M. Kleinman, C. Basbaum, D. Hyde, 2003, Journal of the Air & Waste Management Association.

New HIV-drug inhibits in vitro bladder cancer migration and invasion.

C. Basbaum, M. Retz, H. Tamamura, 2005, European urology.

Tracheal carbohydrate antigens identified by monoclonal antibodies.

C. Basbaum, W. Finkbeiner, L. S. Forsberg, 1986, Archives of biochemistry and biophysics.

Lung mucin production is stimulated by the air pollutant residual oil fly ash.

M. Gallup, C. Basbaum, J. Samet, 2000, Toxicology and applied pharmacology.

MUC5AC mucin gene regulation in pancreatic cancer cells.

C. Basbaum, D. Ahn, S. Crawley, 2006, International journal of oncology.

Cellular Mechanisms of Airway Secretion

D. Gail, C. Basbaum, E. Davidson, 1988 .

Autoradiographic studies of the distribution of 35sulfate label in ferret trachea: effects of stimulation.

J. Nadel, C. Basbaum, A. Gashi, 1987, Experimental lung research.

Regulation of airway secretory cells.

C. Basbaum, 1986, Clinics in chest medicine.

Characterization of a rat airway cDNA encoding a mucin-like protein.

Y. Kim, M. Gallup, C. Basbaum, 1993, Biochemical and Biophysical Research Communications - BBRC.

Regulation of secretion in cultured tracheal serous cells by protein kinases A and C.

G. Cherqui, C. Basbaum, J. Picard, 1991, American Journal of Physiology.

Tracheal submucosal gland serous cells stimulated in vitro with adrenergic and cholinergic agonists A morphometric study

J. Nadel, C. Basbaum, I. Ueki, 2004, Cell and Tissue Research.

Treatment of Cancer

E. Kun, C. Basbaum, V. Ossovskaya, 1998 .

Regulation of mucin gene expression in human tracheobronchial epithelial cells by thyroid hormone

J. Koo, C. Basbaum, P. Nettesheim, 2001 .

Prostaglandins and intracellular cyclic AMP in respiratory secretory cells.

C. Basbaum, S. Lazarus, W. Gold, 1984, The American review of respiratory disease.