Brandon E. Aubol

发表

A conserved sequence motif bridges two protein kinases for enhanced phosphorylation and nuclear function of a splicing factor

J. Adams, Brandon E. Aubol, Laurent Fattet, 2020, The FEBS journal.

SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo

Stephen K Burley, Spencer Emtage, Shane Atwell, 2009, Molecular Cancer Therapeutics.

Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.

Masaki Tomimoto, Charles Kissinger, Anthony M Giannetti, 2008, Bioorganic & medicinal chemistry letters.

Murine DNA cytosine C(5)-methyltransferase: in vitro studies of de novo methylation spreading.

N. Reich, Brandon E. Aubol, 2003, Biochemical and biophysical research communications.

Initiation of Parental Genome Reprogramming in Fertilized Oocyte by Splicing Kinase SRPK1-Catalyzed Protamine Phosphorylation

C. Shao, M. Rosenfeld, Xiang-Dong Fu, 2020, Cell.

Mechanistic insights into Sky1p, a yeast homologue of the mammalian SR protein kinases.

J. Adams, G. Ghosh, Brandon E. Aubol, 2002, Biochemistry.

Molecular interactions connecting the function of the serine-arginine–rich protein SRSF1 to protein phosphatase 1

K. Wüthrich, P. Serrano, J. Adams, 2018, The Journal of Biological Chemistry.

Selective inhibition of MET protein receptor tyrosine kinase by SGX523

J. M. Sauder, S. Burley, J. Blaney, 2007 .

SRPK1 regulates RNA binding in a pre‐spliceosomal complex using a catalytic bypass mechanism

J. Adams, Brandon E. Aubol, 2022, The FEBS journal.

Disordered protein interactions for an ordered cellular transition: Cdc2-like kinase 1 is transported to the nucleus via its Ser–Arg protein substrate

J. Adams, Brandon E. Aubol, Laurent Fattet, 2019, The Journal of Biological Chemistry.

Mobilization of a splicing factor through a nuclear kinase-kinase complex.

J. Adams, Brandon E. Aubol, Laurent Fattet, 2018, The Biochemical journal.

Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex.

Albert C. Chen, J. Adams, A. Engler, 2020, Developmental cell.

Kinetic mechanism of human histidine triad nucleotide binding protein 1.

R. Wolfenden, J. Adams, Chin-Ju Park, 2013, Biochemistry.

Redirecting SR Protein Nuclear Trafficking through an Allosteric Platform.

P. Jennings, J. Adams, Brandon E. Aubol, 2017, Journal of molecular biology.

Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing.

Xiang-Dong Fu, J. Adams, Guowei Wu, 2016, Molecular cell.

Phosphoryl Transfer Step in the C-terminal Src Kinase Controls Src Recognition*

J. Adams, Brandon E. Aubol, Gongqin Sun, 2005, Journal of Biological Chemistry.

Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2.

Xiang-Dong Fu, Sutapa Chakrabarti, Xiang-Dong Fu, 2005, Molecular cell.

Coupling phosphoryl transfer and substrate interactions in protein kinases.

P. Jennings, J. Adams, L. Wong, 2005, Biochimica et biophysica acta.

Processive phosphorylation of alternative splicing factor/splicing factor 2

Xiang-Dong Fu, Sutapa Chakrabarti, Jennifer Shaffer, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Intra-domain Cross-talk Regulates Serine-arginine Protein Kinase 1-dependent Phosphorylation and Splicing Function of Transformer 2β1*

Michael A. Jamros, S. Stamm, J. Adams, 2015, The Journal of Biological Chemistry.

Microsoft Word - Tra2-SRPK1 (w rev comments).docx

Michael A. Jamros, S. Stamm, J. Adams, 2015 .

C 6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1

Manjula., Sunkara, S. Stamm, 2019 .

Dynamic coupling between the SH2 domain and active site of the COOH terminal Src kinase, Csk.

Osamu Miyashita, Virgil L. Woods, Jennifer Shaffer, 2004, Journal of molecular biology.

Nucleotide release sequences in the protein kinase SRPK1 accelerate substrate phosphorylation.

Ryan M. Plocinik, J. Adams, Brandon E. Aubol, 2012, Biochemistry.

Recruiting a Silent Partner for Activation of the Protein Kinase SRPK1

J. Adams, Brandon E. Aubol, 2014, Biochemistry.

Splicing kinase SRPK1 conforms to the landscape of its SR protein substrate.

Michael A. Jamros, J. Adams, Brandon E. Aubol, 2013, Biochemistry.

Partitioning RS domain phosphorylation in an SR protein through the CLK and SRPK protein kinases.

Ryan M. Plocinik, Xiang-Dong Fu, J. Adams, 2013, Journal of molecular biology.

Applying the brakes to multisite SR protein phosphorylation: substrate-induced effects on the splicing kinase SRPK1.

J. Adams, Brandon E. Aubol, 2011, Biochemistry.

N-terminus of the protein kinase CLK1 induces SR protein hyperphosphorylation.

Ryan M. Plocinik, Xiang-Dong Fu, J. Adams, 2014, The Biochemical journal.

Directional Phosphorylation and Nuclear Transport of the Splicing Factor SRSF1 Is Regulated by an RNA Recognition Motif.

K. Wüthrich, P. Serrano, J. Adams, 2016, Journal of molecular biology.

Nuclear protein kinase CLK1 uses a non-traditional docking mechanism to select physiological substrates.

P. Jennings, J. Adams, Brandon E. Aubol, 2015, The Biochemical journal.

CLK1 reorganizes the splicing factor U1-70K for early spliceosomal protein assembly

J. Adams, Brandon E. Aubol, Laurent Fattet, 2021, Proceedings of the National Academy of Sciences.

Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function.

Xiang-Dong Fu, P. Jennings, J. Adams, 2015, The Biochemical journal.

Chemical Clamping Allows for Efficient Phosphorylation of the RNA Carrier Protein Npl3*

J. Adams, G. Ghosh, Brandon E. Aubol, 2004, Journal of Biological Chemistry.

C6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1

S. Stamm, M. Bollen, J. Adams, 2011, Nucleic acids research.

Novel destabilization of nucleotide binding by the gamma phosphate of ATP in the yeast SR protein kinase Sky1p.

J. Adams, G. Ghosh, J. Shaffer, 2003, Biochemistry.