D. Jacobsen

Price To Be Paid for Two-Metal Catalysis: Magnesium Ions That Accelerate Chemistry Unavoidably Limit Product Release from a Protein Kinase

Douglas M. Jacobsen, Charles L. Brooks, D. M. Jacobsen, 2012, Journal of the American Chemical Society.

Briefly bound to activate: transient binding of a second catalytic magnesium activates the structure and dynamics of CDK2 kinase for catalysis.

D. M. Jacobsen, M. Young, Z. Bao, 2011, Structure.

Effect of inhibition of sterol delta 14-reductase on accumulation of meiosis-activating sterol and meiotic resumption in cumulus-enclosed mouse oocytes in vitro.

D. Jacobsen, A. Byskov, C. Andersen, 2000, Journal of reproduction and fertility.

Carrier-mediated transport of folate compounds in L1210 cells. Initial rate kinetics and extent of duality of entry routes for folic acid and diastereomers of 5-methyltetrahydrohomofolate in the presence of physiological anions.

F. Sirotnak, D. Jacobsen, J. Barrueco, 1987, Biochemical pharmacology.

Proposed mechanism of therapeutic selectivity for 9-beta-D-arabinofuranosyl-2-fluoroadenine against murine leukemia based upon lower capacities for transport and phosphorylation in proliferative intestinal epithelium compared to tumor cells.

R. W. Brockman, F. Sirotnak, D. Jacobsen, 1987, Cancer research.

An investigation of the roles of magnesium ions in the catalytic cycle of the protein kinase CDK2: A molecular link between allosteric activation and catalytic activity

D. M. Jacobsen, D. Jacobsen, 2012 .

Fast implementation of a scan statistic for identifying chromosomal patterns of genome wide association studies

Eric Boerwinkle, Stephen T. Turner, Sharon L. R. Kardia, 2009, Comput. Stat. Data Anal..

Alteration of folate analogue transport following induced maturation of HL-60 leukemia cells. Early decline in mediated influx, relationship to commitment, and functional dissociation of entry and exit routes.

F. Sirotnak, D. Jacobsen, C. Yang, 1986, The Journal of biological chemistry.