J. Simard

发表

PBI-4050 Reduces Stellate Cell Activation and Liver Fibrosis through Modulation of Intracellular ATP Levels and the Liver Kinase B1/AMP-Activated Protein Kinase/Mammalian Target of Rapamycin Pathway

J. Richard, B. Grouix, F. Sarra-Bournet, 2018, The Journal of Pharmacology and Experimental Therapeutics.

PBI-4050 Reduces Stellate Cell Activation and Liver Fibrosis through Modulation of Intracellular ATP Levels and the Liver Kinase B1/AMP-Activated Protein Kinase/Mammalian Target of Rapamycin Pathway

J. Richard, B. Grouix, F. Sarra-Bournet, 2018, The Journal of Pharmacology and Experimental Therapeutics.

Interaction between silver nanoparticles of 20 nm (AgNP20) and human neutrophils: induction of apoptosis and inhibition of de novo protein synthesis by AgNP20 aggregates

J. Simard, M. Poirier, Michelle A. Poirier, 2014, Journal of applied toxicology : JAT.

Silver Nanoparticles Induce Degradation of the Endoplasmic Reticulum Stress Sensor Activating Transcription Factor-6 Leading to Activation of the NLRP-3 Inflammasome

J. Simard, F. Vallières, V. Lavastre, 2015, The Journal of Biological Chemistry.

S100A8 and S100A9 Induce Cytokine Expression and Regulate the NLRP3 Inflammasome via ROS-Dependent Activation of NF-κB1

J. Simard, P. Tessier, A. Cesaro, 2013, PloS one.

Damage-Associated Molecular Pattern S100A9 Increases Bactericidal Activity of Human Neutrophils by Enhancing Phagocytosis

J. Simard, P. Tessier, D. Girard, 2011, The Journal of Immunology.

Induction of neutrophil degranulation by S100A9 via a MAPK‐dependent mechanism

J. Simard, P. Tessier, D. Girard, 2010, Journal of leukocyte biology.

Activation of human AML14.3D10 eosinophils by nanoparticles: Modulatory activity on apoptosis and cytokine production

J. Simard, F. Vallières, V. Lavastre, 2016, Journal of immunotoxicology.

Human S100A9 potentiates IL‐8 production in response to GM‐CSF or fMLP via activation of a different set of transcription factors in neutrophils

J. Simard, P. Tessier, D. Girard, 2014, FEBS letters.

A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors: GPR40 and GPR84.

J. Richard, R. Hébert, B. Grouix, 2018, The American journal of pathology.

Silver nanoparticles induce irremediable endoplasmic reticulum stress leading to unfolded protein response dependent apoptosis in breast cancer cells

J. Simard, D. Girard, Isabelle Durocher, 2016, Apoptosis.

Silver nanoparticles of 70 nm and 20 nm affect differently the biology of human neutrophils

J. Simard, M. Poirier, Michelle A. Poirier, 2016, Journal of immunotoxicology.

Prolonged cultures of unstimulated human neutrophils lead to the apparition and persistence of rest-in-plate structures (RIPs) recognized by professional phagocytes in vitro and in vivo.

J. Simard, F. Vallières, D. Girard, 2015, The international journal of biochemistry & cell biology.

PBI-4050 via GPR40 activation improves adenine-induced kidney injury in mice.

R. Hébert, B. Grouix, M. Leduc, 2019, Clinical science.

Gold nanoparticles induce apoptosis, endoplasmic reticulum stress events and cleavage of cytoskeletal proteins in human neutrophils.

J. Simard, D. Girard, Claudie Noël, 2016, Toxicology in vitro : an international journal published in association with BIBRA.

Curcumin inhibits agent-induced human neutrophil functions in vitro and lipopolysaccharide-induced neutrophilic infiltration in vivo.

J. Simard, D. Girard, F. Antoine, 2013, International immunopharmacology.

Viscum album agglutinin-I (VAA-I) increases cell surface expression of cytoskeletal proteins in apoptotic human neutrophils

J. Simard, D. Girard, M. Simon, 2013, Human & experimental toxicology.

Fatty acid mimetic PBI-4547 restores metabolic homeostasis via GPR84 in mice with non-alcoholic fatty liver disease

S. LaPlante, B. Grouix, F. Sarra-Bournet, 2020, Scientific Reports.

Quinoline-3-carboxamides such as tasquinimod are not specific inhibitors of S100A9.

J. Simard, P. Tessier, M. Pelletier, 2018, Blood advances.

PBI-4050 reduces stellate cell activation and liver fibrosis through modulation of intracellular ATP levels and LKB1-AMPK-mTOR pathway

J. Richard, B. Grouix, F. Sarra-Bournet, 2018 .