P. Reeves

发表

Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration

Peter M. G. Munro, K. Palczewski, D. Athanasiou, 2016, Human molecular genetics.

A Conserved Proline Hinge Mediates Helix Dynamics and Activation of Rhodopsin.

K. South, P. Reeves, Steven O. Smith, 2020, Structure.

Do Plants Contain G Protein-Coupled Receptors?1[C][W][OPEN]

Graham J. G. Upton, C. Reynolds, G. Upton, 2013, Plant Physiology.

Structure and function in rhodopsin: High-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line

Roland Contreras, Nico Callewaert, Philip J. Reeves, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Opsin stability and folding: modulation by phospholipid bicelles.

H Gobind Khorana, H. Khorana, B. Wallace, 2007, Journal of molecular biology.

Retinitis Pigmentosa Mutants Provide Insight into the Role of the N-terminal Cap in Rhodopsin Folding, Structure, and Function*

C. Reynolds, C. A. Opefi, K. South, 2013, The Journal of Biological Chemistry.

Opsin is present as dimers in COS1 cells: identification of amino acids at the dimeric interface.

H. Khorana, P. Reeves, U. RajBhandary, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Assessing the effect of dynamics on the closed-loop protein-folding hypothesis

Christopher J. R. Illingworth, G. Upton, C. J. Illingworth, 2014, Journal of The Royal Society Interface.

NMR spectroscopy in studies of light-induced structural changes in mammalian rhodopsin: applicability of solution (19)F NMR.

J. Klein-Seetharaman, H. Khorana, P. Reeves, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Phase Behavior during Electrochemical Cycling of Ni‐Rich Cathode Materials for Li‐Ion Batteries

Chaodi Xu, C. Grey, P. Reeves, 2020, Advanced Energy Materials.

Light-driven activation of beta 2-adrenergic receptor signaling by a chimeric rhodopsin containing the beta 2-adrenergic receptor cytoplasmic loops.

Pere Garriga, H Gobind Khorana, H. Khorana, 2005, Biochemistry.

G Protein-Coupled Receptors Contain Two Conserved Packing Clusters.

P. Reeves, M. Eilers, Steven O. Smith, 2017, Biophysical journal.

Structure and function in rhodopsin: high level expression of a synthetic bovine opsin gene and its mutants in stable mammalian cell lines.

H. Khorana, R. Thurmond, P. Reeves, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Pushing the limit of 3d transition metal-based layered oxides that use both cation and anion redox for energy storage

M. Whittingham, Y. Meng, C. Grey, 2022, Nature Reviews Materials.

Beta‐lactamase topology probe analysis of the OutO NMePhe peptidase, and six other Out protein components of the Erwinia carotovora general secretion pathway apparatus

G. Salmond, P. Reeves, P. Douglas, 1994, Molecular microbiology.

The general secretion pathway of Erwinia carotovora subsp. carotovora: analysis of the membrane topology of OutC and OutF.

J. D. Thomas, G. Salmond, P. Reeves, 1997, Microbiology.

17O NMR Spectroscopy in Lithium-Ion Battery Cathode Materials: Challenges and Interpretation

C. Grey, P. Reeves, I. Seymour, 2022, Journal of the American Chemical Society.

Bulk Fatigue Induced by Surface Reconstruction in Layered Ni-Rich Oxide Cathodes for Liion Batteries

B. L. Mehdi, C. Grey, P. Reeves, 2020 .

Evolution of Structure and Lithium Dynamics in LiNi0.8Mn0.1Co0.1O2 (NMC811) Cathodes during Electrochemical Cycling

Kent J. Griffith, Chaodi Xu, C. Grey, 2019, Chemistry of Materials.

NMR spectroscopy of phosphorylated wild-type rhodopsin: mobility of the phosphorylated C-terminus of rhodopsin in the dark and upon light activation.

J. Klein-Seetharaman, H. Khorana, M. Sheves, 2004, Biochemistry.

Bulk fatigue induced by surface reconstruction in layered Ni-rich cathodes for Li-ion batteries

Chaodi Xu, C. Grey, P. Reeves, 2020, Nature Materials.

Differences in SMA-like polymer architecture dictate the conformational changes exhibited by the membrane protein rhodopsin encapsulated in lipid nano-particles

C. Tate, P. Reeves, B. Klumperman, 2021, Nanoscale.

Dipolar assisted rotational resonance NMR of tryptophan and tyrosine in rhodopsin

H. Khorana, M. Sheves, Shobini Jayaraman, 2004, Journal of biomolecular NMR.

Magic angle spinning NMR of the protonated retinylidene Schiff base nitrogen in rhodopsin: expression of 15N-lysine- and 13C-glycine-labeled opsin in a stable cell line.

S. O. Smith, H. Khorana, P. Reeves, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Bulk and Surface Chemistry of the Niobium MAX and MXene Phases from Multinuclear Solid-State NMR Spectroscopy.

Kent J. Griffith, C. Grey, Y. Gogotsi, 2020, Journal of the American Chemical Society.

Expression and purification of rhodopsin and its mutants from stable mammalian cell lines: application to NMR studies.

S. O. Smith, J. Klein-Seetharaman, H. Khorana, 1999, Biochemical Society transactions.

Structure and function in rhodopsin: peptide sequences in the cytoplasmic loops of rhodopsin are intimately involved in interaction with rhodopsin kinase.

H. Khorana, R. Thurmond, P. Reeves, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Molecular genetic analysis of global regulation of extracellular enzyme synthesis in Erwinia carotovora subspecies carotovora

G. Salmond, P. Reeves, P. Golby, 1994 .

Conditional mutations in OutE and OutL block exoenzyme secretion across the Erwinia carotovora outer membrane.

J. D. Thomas, G. Salmond, P. Reeves, 1998, FEMS microbiology letters.

Intrinsic Kinetic Limitations in Substituted Lithium Layered Transition-Metal Oxide Electrodes.

C. Grey, P. Reeves, Hao Liu, 2020, Journal of the American Chemical Society.

Synthesis, structure and magnetism of the new S = 1 kagome magnet NH4Ni2.5V2O7(OH)2⋅H2O

D. Boldrin, P. Reeves, A. Wills, 2018, Journal of physics. Condensed matter : an Institute of Physics journal.

Changes in interhelical hydrogen bonding upon rhodopsin activation.

Markus Eilers, H Gobind Khorana, H. Khorana, 2005, Journal of molecular biology.

Magic angle spinning nuclear magnetic resonance spectroscopy of G protein-coupled receptors.

P. Reeves, M. Eilers, Steven O. Smith, 2013, Methods in enzymology.

Evolution of lithium ordering with (de)-lithiation in β-LiVOPO4: insights through solid-state NMR and first principles DFT calculations

M. Whittingham, C. Grey, P. Reeves, 2020 .

Short-range ordering in a battery electrode, the 'cation-disordered' rocksalt Li1.25Nb0.25Mn0.5O2.

C. Grey, P. Reeves, M. Cliffe, 2019, Chemical communications.

Structural transitions of transmembrane helix 6 in the formation of metarhodopsin I.

A. Hirshfeld, C. Simmerling, M. Sheves, 2012, The journal of physical chemistry. B.

Free backbone carbonyls mediate rhodopsin activation

P. Reeves, M. Eilers, Steven O. Smith, 2016, Nature Structural &Molecular Biology.

Light activation of rhodopsin: insights from molecular dynamics simulations guided by solid-state NMR distance restraints.

V. Hornak, M. Sheves, P. Reeves, 2010, Journal of molecular biology.

Helix Movement is Coupled to Displacement of the Second Extracellular Loop in Rhodopsin Activation

Viktor Hornak, Markus Eilers, Philip J. Reeves, 2009, Nature Structural &Molecular Biology.

Structure and function in rhodopsin: destabilization of rhodopsin by the binding of an antibody at the N-terminal segment provides support for involvement of the latter in an intradiscal tertiary structure.

H. Khorana, P. Reeves, K. Cha, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Amino acid conservation and interactions in rhodopsin: probing receptor activation by NMR spectroscopy.

P. Reeves, M. Eilers, Steven O. Smith, 2014, Biochimica et biophysica acta.

Retinal orientation and interactions in rhodopsin reveal a two-stage trigger mechanism for activation

A. Hirshfeld, M. Sheves, P. Reeves, 2016, Nature Communications.

Uncovering the triggers for GPCR activation using solid-state NMR spectroscopy.

P. Reeves, Steven O. Smith, Naoki Kimata, 2015, Journal of magnetic resonance.

Designer short peptide surfactants stabilize G protein-coupled receptor bovine rhodopsin

H. Khorana, Shuguang Zhang, P. Reeves, 2006, Proceedings of the National Academy of Sciences.

The molecular and cellular basis of rhodopsin retinitis pigmentosa reveals potential strategies for therapy

D. Athanasiou, M. Aguilà, J. Bellingham, 2017, Progress in Retinal and Eye Research.

A pleiotropic reduced virulence (Rvi‐) mutant of Erwinia carotovora subspecies atroseptica is defective in flagella assembly proteins that are conserved in plant and animal bacterial pathogens

G. Salmond, P. Reeves, J. Hinton, 1993, Molecular microbiology.

The lux autoinducer regulates the production of exoenzyme virulence determinants in Erwinia carotovora and Pseudomonas aeruginosa.

P. Reeves, S. R. Chhabra, B. Bycroft, 1993, The EMBO journal.

The major secreted cellulase, CelV, of Erwinia carotovora subsp. carotovora is an important soft rot virulence factor

Denise S Walker, G. Salmond, P. Reeves, 1994 .

A novel strategy for the isolation of luxl homologues: evidence for the widespread distribution of a LuxR:Luxl superfamily in enteric bacteria

G. Salmond, P. Reeves, S. Swift, 1993, Molecular microbiology.

Molecular cloning and characterization of 13 out genes from Erwinia carotovora subspecies carotovora: genes encoding members of a general secretion pathway (GSP) widespread in Gram‐negative bacteria

Denise S Walker, G. Salmond, D. Whitcombe, 1993, Molecular microbiology.

Theluxautoinducer regulates theproduction of exoenzyme virulence determinants inErwinia carotovora andPseudomonas aeruginosa

G. Salmond, P. Reeves, M. Winson, 1993 .

Construction of Recombinant Cell Lines for GPCR Expression.

P. Reeves, 2021, Methods in molecular biology.

Characterizing the Structure and Phase Transition of Li2RuO3 Using Variable-Temperature 17O and 7Li NMR Spectroscopy

Kent J. Griffith, C. Grey, P. Reeves, 2019, Chemistry of Materials.

Computational studies of Family A and Family B GPCRs.

Christopher J. R. Illingworth, Graham J. G. Upton, C. Reynolds, 2007, Biochemical Society transactions.

Differential dynamics in the G protein-coupled receptor rhodopsin revealed by solution NMR.

J. Klein-Seetharaman, H. Schwalbe, H. Khorana, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Electrochemical Performance of Nanosized Disordered LiVOPO4

M. Whittingham, C. Grey, P. Reeves, 2018, ACS omega.

Membrance traffic wardens and protein secretion in Gram-negative bacteria

Philip J. Reeves, G. Salmond, P. Reeves, 1993 .

Membrane traffic wardens and protein secretion in gram-negative bacteria.

G. Salmond, P. Reeves, G P Salmond, 1993, Trends in biochemical sciences.

Expression systems for bovine rhodopsin: a review of the progress made in the Khorana laboratory

P. Reeves, 2023, Biophysical Reviews.

Structure and function in rhodopsin: A tetracycline-inducible system in stable mammalian cell lines for high-level expression of opsin mutants

Philip J. Reeves, H. Khorana, P. Reeves, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Rhodopsin kinase: expression in mammalian cells and a two-step purification.

H. Khorana, P. Reeves, E. Getmanova, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Structural and functional roles of small group-conserved amino acids present on helix-H7 in the β(2)-adrenergic receptor.

P. Reeves, M. Eilers, Steven O. Smith, 2011, Biochimica et biophysica acta.

Revisiting the charge compensation mechanisms in LiNi0.8Co0.2−yAlyO2 systems

Anton Van der Ven, C. Grey, G. Amatucci, 2019, Materials Horizons.

Rhodopsin kinase: two mAbs binding near the carboxyl terminus cause time-dependent inactivation.

H. Khorana, P. Reeves, L. Niu, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Structural Origins of Voltage Hysteresis in the Na-Ion Cathode P2–Na0.67[Mg0.28Mn0.72]O2: A Combined Spectroscopic and Density Functional Theory Study

C. Grey, P. Reeves, G. Cibin, 2021, Chemistry of materials : a publication of the American Chemical Society.

Structure and Mechanism in G Protein-coupled Receptors

H. Khorana, P. Reeves, Jong-Myoung Kim, 2002 .

Bruck Taddese, Graham J. G. Upton, Christopher A. Reynolds, 2013, Journal of The Royal Society Interface.

Effect of cultivar and soil characteristics on nutritional value in organic and conventional wheat

P. Reeves, L. Hoagland, K. Murphy, 2008 .

Magic angle spinning NMR of the protonated retinylidene Schiff base nitrogen in rhodopsin: Expression of 15 N-lysine- and 13 C-glycine-labeled opsin in a stable cell line (HEK293S cellsyG protein-coupled receptorysignal transductiony11-cis retinalyvisual pigment)

H. Khorana, P. Reeves, M. Eilers, 1999 .

The synthesis and high‐level expression of a β2‐adrenergic receptor gene in a tetracycline‐inducible stable mammalian cell line

H. Khorana, P. Reeves, P. Chelikani, 2006, Protein science : a publication of the Protein Society.

Location of the Retinal Chromophore in the Activated State of Rhodopsin*

H. Khorana, V. Hornak, A. Hirshfeld, 2009, Journal of Biological Chemistry.

Structure and function in rhodopsin: kinetic studies of retinal binding to purified opsin mutants in defined phospholipid-detergent mixtures serve as probes of the retinal binding pocket.

H. Khorana, P. Reeves, H G Khorana, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Solution NMR spectroscopy of [α-15N]lysine-labeled rhodopsin: The single peak observed in both conventional and TROSY-type HSQC spectra is ascribed to Lys-339 in the carboxyl-terminal peptide sequence

J. Klein-Seetharaman, H. Schwalbe, H. Khorana, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Solution 19F nuclear Overhauser effects in structural studies of the cytoplasmic domain of mammalian rhodopsin

J. Klein-Seetharaman, H. Schwalbe, H. Khorana, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Structure and function in rhodopsin: further elucidation of the role of the intradiscal cysteines, Cys-110, -185, and -187, in rhodopsin folding and function.

J. Klein-Seetharaman, H. Khorana, P. Reeves, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Magic angle spinning nuclear magnetic resonance of isotopically labeled rhodopsin.

H. Khorana, P. Reeves, M. Eilers, 2002, Methods in enzymology.

Highly conserved tyrosine stabilizes the active state of rhodopsin

P. Reeves, M. Eilers, Steven O. Smith, 2010, Proceedings of the National Academy of Sciences.

The Molecular Switching Mechanism at the Conserved D(E)RY Motif in Class-A GPCRs.

R. Böckmann, K. Fahmy, P. Reeves, 2016, Biophysical journal.

A pleiotropic reduced virulence (Rvi−) mutant of Erwinia carotovora subspecies atroseptica is defective in flagella assembly proteins that are conserved in plant and animal bacterial pathogens

G. Salmond, P. Reeves, J. Hinton, 1993, Molecular microbiology.

Short-range ordering in battery electrode, the ‘cation-disordered’

P. Reeves, M. Cliffe, I. Seymour, 2019 .

Do Plants Contain G Protein-Coupled Receptors?1[C][W][OPEN]

Graham J. G. Upton, P. Reeves, Bruck Taddese, 2013, Plant Physiology.

Molecular genetic analysis of extracellular enzyme secretion by Erwinia carotovora

P. Reeves, 1991 .

High-Level Expression, Single-Step Immunoaffinity Purification and Characterization of Human Tetraspanin Membrane Protein CD81

H. Khorana, Shuguang Zhang, P. Reeves, 2008, PloS one.

Opsin stability and folding: the role of Cys185 and abnormal disulfide bond formation in the intradiscal domain.

H. Khorana, P. Booth, P. Reeves, 2007, Journal of molecular biology.

Closed loop folding units from structural alignments: Experimental foldons revisited

Christopher J. R. Illingworth, Graham J. G. Upton, Kevin E. B. Parkes, 2010, J. Comput. Chem..

High-Level Expression , Single-Step Immunoaffinity Purification and Characterization of Human Tetraspanin Membrane Protein CD 81

H. Khorana, Shuguang Zhang, P. Reeves, 2008 .